1JIZA

Crystal structure analysis of human macrophage elastase mmp-12
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
166
structure length
166
Chain Sequence
GFREMPGGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDFHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYGD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of human macrophage elastase (MMP-12) in complex with a hydroxamic acid inhibitor.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords macrophage elastase MMP-12
total genus 49
structure length 166
sequence length 166
chains with identical sequence B
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2001-07-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 1jizA00
1RM8A 1PWVA 2W13A 3AYKA 4GR8A 1QUAA 1HY7A 3KEJA 2AYKA 3B2ZA 3HDAP 4AXQA 1CIZA 5I4OA 3LJZA 2PJTA 5D1UA 4JIJA 4GWNA 3LILA 1FLSA 3LMCA 5L7FA 3ZUKA 4PKVA 1G49A 1XUCA 1UMTA 2ERQA 3HY7A 3LEAA 4JA1A 3HBUP 3VI1A 4PKUA 1JANA 966CA 2JSDA 3LGPA 3G42A 3MA2A 1OM6A 1S4BP 2OVZA 1ZP5A 5CZMA 5BOYA 3CKIA 1BKCE 1HOVA 5D1SA 1XURA 4I35A 2OY2A 1JIWP 1JKYA 1R55A 1C7KA 1J7NA 2X3BA 3L0TA 1HV5A 1IAEA 2W12A 3EDHA 5CXAA 4L63A 1GXDA 4L19A 3O2XA 1ZXCA 5I2ZA 4FXYP 1OS9A 4WZVA 3U1RA 2FV5A 1JK3A 2Y6DA 4DV8A 1D8MA 1GKCA 1G05A 4XM7A 3Q2GA 1QJIA 1MNCA 4JQGA 3B8ZA 3LK8A 3Q2HA 3K7NA 4WF6A 4GR3A 5I0LA 1Q3AA 3NX7A 2E2DA 1CXVA 1MMBA 1XFUA 3F18A 1OM8A 1B3DA 4XCTA 3LJTA 5B5PA 1G4KA 1MMQA 1IAGA 4J4MA 2ERPA 2DDFA 4A7BA 1QJJA 4AUOA 1QIBA 1OMJA 2D1OA 1JAPA 3LE9A 1DMTA 2MLSA 2JNPA 3KMEA 1ZTQA 3P1VA 2YB9A 3TS4A 1IABA 2E3XA 2WOAA 1JAOA 4H3XA 2JT6A 4PKWA 4XM8A 4H84A 4IN9A 1B8YA 3I7IA 2W0DA 3KECA 1K7GA 1JH1A 1RMZA 3F19A 1A85A 1YQYA 2DW1A 4H76A 1JAQA 1BKCA 4DF9A 5CUHA 3L0VA 1BQOA 1Z3JA 4GWMA 1K7QA 1XUDA 1JIZA 4L6TA 1OM7A 1R1HA 1O0TA 2MLRA 1PWWA 3LUMA 1KBCA 1PWUA 5BOTA 3F15A 1D8FA 2AIGP 5I12A 1BM6A 2OW9A 4FXQA 4EFSA 1SRPA 1CK7A 1G9KA 1XFVA 2USNA 4PKRA 3VTGA 1FBLA 1XFXA 1KUHA 1UTZA 2V4BA 2FV9A 2Y6CA 456CA 3WV2A 3DL1A 1EUBA 3KHIA 3DPFA 3EHXA 3HBVP 4JP4A 2TCLA 3EWJA 1SATA 2X3AA 2W14A 4A3WA 2OW1A 1ATLA 3HB2P 5L79A 2J0TA 4H82A 2JIHA 2WO9A 4H49A 4WKIA 2YIGA 3HDBA 3LUNA 1O0QA 1BZSA 4HMAA 1D5JA 4IUWA 1YCMA 3O64A 1GE6A 1YP1A 1IADA 3LIKA 1G12A 2O3EA 1FM1A 4DD8A 2I47A 2D1NA 1GKDA 3TSKA 1GE5A 4GUYA 4I03A 3V96B 2J83A 5BPAA 2K9CA 3HY9A 4PKQA 1PWPA 1KUKA 1WNIA 4H2EA 2O36A 3AIGA 3G5CA 1YOUA 1SLMA 1SLNA 3LQ0A 5D2BA 4XM6A 1CAQA 3ZXHA 3ZVSA 1KUGA 5I3MA 3K7LA 2L0RA 2POJA 2OXWA 3LJGA 3N2VA 4CTHA 1AKLA 4PKSA 3WV3A 4JPAA 3E8RA 1OO9A 3USNA 3EDIA 3HYGA 3RTSA 3KEKA 5JMYA 1KAPP 4H30A 1BIWA 3F1AA 2OW0A 2OXZA 2OXUA 1Y8JA 1MMRA 2SRTA 1D7XA 1I73A 2KRJA 3I7GA 2A8HA 4ZR5A 3DWBA 3EHYA 1IAAA 4FU4A 1DTHA 2OI0A 1AF0A 3KWVC 2Z2DA 1HFCA 2CLTA 2XS3A 1QIAA 1BSWA 1EAKA 1ROSA 3LIRA 3LKAA 5LABA 4DPEA 3EDZA 1R54A 3BA0A 1USNA 2HU6A 1IACA 2JT5A 4GF1A 3ELMA 1BUVM 1UMSA 1Y0VA 3EDGA 2RJQA 2OW2A 1PWQA 2WO8A 3RTTA 1SMPA 4XBHA 1Y93A 1C8TA 3DSLA 1HFSA 3OHLA 5I43A 2CKIA 4WK7A 2XS4A 4AIGA 1OS2A 1CQRA 4WKEA 5D1TA 1XFWA 2RJPA 4IJOA 4FVLA 3TT4A 3SHIA 1K7IA 1CGLA 1GE7A 1XFZA 1BKCI 3DNGA 5B5OA 2N8RA 1ASTA 2X7MA 1UEAA 1CGFA 3B92A 1ZVXA 1HTDA 2DW0A 3N2UA 2K2GA 4Q1LA 2MZIA 3UVCA 2X3CA 4ON1A 1AYKA 4ILWD 4R3VA 3P24A 3DPEA 3WV1A 1BQQM 2OZRA 1GO8P 1I1IP 4QKZA 1I76A 1SU3A 3LQBA 4HX3A 1R1JA 830CA 1ND1A 3F17A 4PKTA 1MMPA 4AYKA 1KUIA 4G9LA 1CGEA 1L6JA 2DDYA 1EB6A 2OY4A 1XFYA 1KUFA 1A86A 1GO7P 3GBOA 1QICA 3OHOA 2DW2A 3F16A 3TVCA 1C3IA 1UTTA 1R1IA 5D7WA 5H8XA 1BUDA 1JJ9A 1H71P 1ZXVA 3KMCA 2MZEA 3KRYA 2MZHA 4GQLA 4H1QA 2EROA 2OVXA 2W15A 5D3CA 1ZS0A 4G0DA 2QPJA 3AYUA 4GR0A
chains in the Genus database with same CATH superfamily
1RM8A 1PWVA 2W13A 3AYKA 4GR8A 1QUAA 1HY7A 3KEJA 2AYKA 3B2ZA 3HDAP 4L7AA 1CIZA 4AXQA 5I4OA 3LJZA 2PJTA 5D1UA 4JIJA 4GWNA 3LILA 1FLSA 3LMCA 5L7FA 3ZUKA 4PKVA 3DTIA 1G49A 1XUCA 1UMTA 2ERQA 3HY7A 3LEAA 4JA1A 3HBUP 3VI1A 4PKUA 1JANA 966CA 2JSDA 3LGPA 3G42A 3MA2A 1OM6A 1S4BP 2OVZA 1ZP5A 5CZMA 5BOYA 3CKIA 1BKCE 1HOVA 5D1SA 1XURA 4I35A 2OY2A 1JIWP 1JKYA 1R55A 1C7KA 1J7NA 2X3BA 3L0TA 1HV5A 1IAEA 2W12A 3EDHA 5CXAA 4L63A 1GXDA 4L19A 3O2XA 1ZXCA 5I2ZA 4FXYP 1OS9A 4WZVA 3U1RA 2FV5A 1JK3A 2Y6DA 4DV8A 3DTKA 1D8MA 1GKCA 1G05A 4XM7A 3Q2GA 1QJIA 1MNCA 4JQGA 3B8ZA 3LK8A 3Q2HA 3K7NA 4WF6A 4GR3A 5I0LA 1Q3AA 3NX7A 2E2DA 1CXVA 1MMBA 1XFUA 3F18A 1OM8A 1B3DA 4XCTA 3LJTA 5B5PA 1G4KA 1MMQA 1IAGA 4J4MA 2ERPA 2DDFA 4A7BA 1QJJA 4AUOA 1QIBA 1OMJA 2D1OA 1JAPA 3LE9A 1DMTA 2MLSA 2JNPA 3KMEA 1ZTQA 3P1VA 2YB9A 3TS4A 1IABA 2E3XA 2WOAA 1JAOA 4H3XA 2JT6A 4PKWA 4XM8A 4H84A 4IN9A 1B8YA 3I7IA 2W0DA 3KECA 1K7GA 1JH1A 1RMZA 3F19A 1A85A 1YQYA 2DW1A 4H76A 1JAQA 1BKCA 4DF9A 5CUHA 3L0VA 1BQOA 1Z3JA 4GWMA 1K7QA 1XUDA 1JIZA 4L6TA 1OM7A 1R1HA 1O0TA 2MLRA 1PWWA 3LUMA 1KBCA 1PWUA 5BOTA 3F15A 1D8FA 2AIGP 5I12A 1BM6A 2OW9A 4FXQA 4EFSA 1SRPA 1CK7A 1G9KA 1XFVA 2USNA 4PKRA 3VTGA 1FBLA 1XFXA 1KUHA 1UTZA 2V4BA 2FV9A 2Y6CA 456CA 3WV2A 3DL1A 1EUBA 3KHIA 3DPFA 3EHXA 3HBVP 4JP4A 2TCLA 3EWJA 1SATA 2X3AA 2W14A 4A3WA 2OW1A 1ATLA 3HB2P 5L79A 2J0TA 4H82A 2JIHA 2WO9A 4H49A 4WKIA 2YIGA 3HDBA 3LUNA 1O0QA 1BZSA 4HMAA 1D5JA 4IUWA 1YCMA 3O64A 1GE6A 1YP1A 1IADA 3LIKA 1G12A 2O3EA 1FM1A 4DD8A 2I47A 2D1NA 1GKDA 3TSKA 1GE5A 4GUYA 4I03A 3V96B 2J83A 5BPAA 2K9CA 3HY9A 4PKQA 1PWPA 1TVIA 1KUKA 1WNIA 4H2EA 2O36A 3AIGA 3G5CA 1YOUA 1SLMA 1SLNA 3LQ0A 5D2BA 4XM6A 1CAQA 3ZXHA 3ZVSA 1KUGA 5I3MA 3K7LA 2L0RA 2POJA 2OXWA 3LJGA 3N2VA 4CTHA 1AKLA 4PKSA 3WV3A 4JPAA 3E8RA 1OO9A 3USNA 3EDIA 3HYGA 3RTSA 3KEKA 5JMYA 1KAPP 4H30A 1BIWA 3F1AA 2OW0A 2OXZA 2OXUA 1Y8JA 1MMRA 2SRTA 1D7XA 1I73A 2KRJA 3I7GA 2A8HA 4ZR5A 3DTEA 3DWBA 3EHYA 1IAAA 4FU4A 1DTHA 2OI0A 1AF0A 3KWVC 2Z2DA 1HFCA 2CLTA 2XS3A 1QIAA 1BSWA 1EAKA 1ROSA 3LIRA 3LKAA 5LABA 4DPEA 3EDZA 1R54A 3BA0A 1OZ9A 1USNA 2HU6A 1IACA 2JT5A 4GF1A 3ELMA 1BUVM 1UMSA 1Y0VA 3EDGA 2RJQA 2OW2A 1PWQA 2WO8A 3RTTA 1SMPA 4XBHA 1Y93A 1C8TA 3DSLA 1HFSA 3OHLA 5I43A 2CKIA 4WK7A 2XS4A 4AIGA 1OS2A 1CQRA 1XM5A 4WKEA 5D1TA 1XFWA 2RJPA 4IJOA 4FVLA 3TT4A 3SHIA 1K7IA 1CGLA 1GE7A 1XFZA 1BKCI 3DNGA 5B5OA 2N8RA 1ASTA 2X7MA 1UEAA 1CGFA 3B92A 1ZVXA 1HTDA 2DW0A 3N2UA 2K2GA 4Q1LA 2MZIA 3UVCA 2X3CA 4ON1A 1AYKA 4ILWD 4R3VA 3P24A 3DPEA 3WV1A 1BQQM 2OZRA 1GO8P 1I1IP 4QKZA 1I76A 1SU3A 3LQBA 4HX3A 1R1JA 830CA 1ND1A 1XAXA 3F17A 4PKTA 1MMPA 4AYKA 1KUIA 4G9LA 1CGEA 1L6JA 2DDYA 1EB6A 2OY4A 1XFYA 1KUFA 1A86A 1GO7P 3GBOA 1QICA 3OHOA 2DW2A 3F16A 3TVCA 2YUFA 1C3IA 1UTTA 1R1IA 5D7WA 5H8XA 1BUDA 1JJ9A 1H71P 1ZXVA 3KMCA 2MZEA 3KRYA 2MZHA 4GQLA 4H1QA 2EROA 2OVXA 2W15A 5D3CA 1ZS0A 4G0DA 2QPJA 3AYUA 4GR0A
chains in the Genus database with same CATH topology
1RM8A 1PWVA 2W13A 3AYKA 4GR8A 1QUAA 1HY7A 3KEJA 2AYKA 3B2ZA 3HDAP 4L7AA 1CIZA 4AXQA 5I4OA 3LJZA 2PJTA 5D1UA 4JIJA 4GWNA 3LILA 1FLSA 3LMCA 5L7FA 3ZUKA 4PKVA 3DTIA 1G49A 1XUCA 1UMTA 2ERQA 3HY7A 3LEAA 4JA1A 3HBUP 3VI1A 4PKUA 1JANA 966CA 2JSDA 3LGPA 3G42A 3MA2A 1OM6A 1S4BP 2OVZA 1ZP5A 5CZMA 5BOYA 3CKIA 1BKCE 1HOVA 5D1SA 1XURA 4I35A 2OY2A 1JIWP 1JKYA 1R55A 1C7KA 1J7NA 2X3BA 3L0TA 1HV5A 1IAEA 2W12A 3EDHA 5CXAA 4L63A 1GXDA 4L19A 3O2XA 1ZXCA 5I2ZA 4FXYP 1OS9A 4WZVA 3U1RA 2FV5A 1JK3A 2Y6DA 4DV8A 3DTKA 1D8MA 1GKCA 1G05A 4XM7A 3Q2GA 1QJIA 1MNCA 4JQGA 3B8ZA 3LK8A 3Q2HA 3K7NA 4WF6A 4GR3A 5I0LA 1Q3AA 3NX7A 2E2DA 1CXVA 1MMBA 1XFUA 3F18A 1OM8A 1B3DA 4XCTA 3LJTA 5B5PA 1G4KA 1MMQA 1IAGA 4J4MA 2ERPA 2DDFA 4A7BA 1QJJA 4AUOA 1QIBA 1OMJA 2D1OA 1JAPA 3LE9A 1DMTA 2MLSA 2JNPA 3KMEA 1ZTQA 3P1VA 2YB9A 3TS4A 1IABA 2E3XA 2WOAA 1JAOA 4H3XA 2JT6A 4PKWA 4XM8A 4H84A 4IN9A 1B8YA 3I7IA 2W0DA 3KECA 1K7GA 1JH1A 1RMZA 3F19A 1A85A 1YQYA 2DW1A 4H76A 1JAQA 1BKCA 4DF9A 5CUHA 3L0VA 1BQOA 1Z3JA 4GWMA 1K7QA 1XUDA 1JIZA 4L6TA 1OM7A 1R1HA 1O0TA 2MLRA 1PWWA 3LUMA 1KBCA 1PWUA 5BOTA 3F15A 1D8FA 2AIGP 5I12A 1BM6A 2OW9A 4FXQA 4EFSA 1SRPA 1CK7A 1G9KA 1XFVA 2USNA 4PKRA 3VTGA 1FBLA 1XFXA 1KUHA 1UTZA 2V4BA 2FV9A 2Y6CA 456CA 3WV2A 3DL1A 1EUBA 3KHIA 3DPFA 3EHXA 3HBVP 4JP4A 2TCLA 3EWJA 1SATA 2X3AA 2W14A 4A3WA 2OW1A 1ATLA 3HB2P 5L79A 2J0TA 4H82A 2JIHA 2WO9A 4H49A 4WKIA 2YIGA 3HDBA 3LUNA 1O0QA 1BZSA 4HMAA 1D5JA 4IUWA 1YCMA 3O64A 1GE6A 1YP1A 1IADA 3LIKA 1G12A 2O3EA 1FM1A 4DD8A 2I47A 2D1NA 1GKDA 3TSKA 1GE5A 4GUYA 4I03A 3V96B 2J83A 5BPAA 2K9CA 3HY9A 4PKQA 1PWPA 1KUKA 1WNIA 4H2EA 2O36A 3AIGA 3G5CA 1YOUA 1SLMA 1SLNA 3LQ0A 5D2BA 4XM6A 1CAQA 3ZXHA 3ZVSA 1KUGA 5I3MA 3K7LA 2L0RA 2POJA 2OXWA 3LJGA 3N2VA 4CTHA 1AKLA 4PKSA 3WV3A 4JPAA 3E8RA 1OO9A 3USNA 3EDIA 3HYGA 3RTSA 3KEKA 5JMYA 1KAPP 4H30A 1BIWA 3F1AA 2OW0A 2OXZA 2OXUA 1Y8JA 1MMRA 2SRTA 1D7XA 1I73A 2KRJA 3I7GA 2A8HA 4ZR5A 3DTEA 3DWBA 3EHYA 1IAAA 4FU4A 1DTHA 2OI0A 1AF0A 3KWVC 2Z2DA 1HFCA 2CLTA 2XS3A 1QIAA 1BSWA 1EAKA 1ROSA 3LIRA 3LKAA 5LABA 4DPEA 3EDZA 1R54A 3BA0A 1USNA 2HU6A 1IACA 2JT5A 4GF1A 3ELMA 1BUVM 1UMSA 1Y0VA 3EDGA 2RJQA 2OW2A 1PWQA 2WO8A 3RTTA 1SMPA 4XBHA 1Y93A 1C8TA 3DSLA 1HFSA 3OHLA 5I43A 2CKIA 4WK7A 2XS4A 4AIGA 1OS2A 1CQRA 4WKEA 5D1TA 1XFWA 2RJPA 4IJOA 4FVLA 3TT4A 3SHIA 1K7IA 1CGLA 1GE7A 1XFZA 1BKCI 3DNGA 5B5OA 2N8RA 1ASTA 2X7MA 1UEAA 1CGFA 3B92A 1ZVXA 1HTDA 2DW0A 3N2UA 2K2GA 4Q1LA 2MZIA 3UVCA 2X3CA 4ON1A 1AYKA 4ILWD 4R3VA 3P24A 3DPEA 3WV1A 1BQQM 2OZRA 1GO8P 1I1IP 4QKZA 1I76A 1SU3A 3LQBA 4HX3A 1R1JA 830CA 1ND1A 3F17A 4PKTA 1MMPA 4AYKA 1KUIA 4G9LA 1CGEA 1L6JA 2DDYA 1EB6A 2OY4A 1XFYA 1KUFA 1A86A 1GO7P 3GBOA 1QICA 3OHOA 2DW2A 3F16A 3TVCA 2YUFA 1C3IA 1UTTA 1R1IA 5D7WA 5H8XA 1BUDA 1JJ9A 1H71P 1ZXVA 3KMCA 2MZEA 3KRYA 2MZHA 4GQLA 4H1QA 2EROA 2OVXA 2W15A 5D3CA 1ZS0A 4G0DA 2QPJA 3AYUA 4GR0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RM8 A;  1PWV A;  2W13 A;  3AYK A;  4GR8 A;  1QUA A;  1HY7 A;  3KEJ A;  2AYK A;  3B2Z A;  3HDA P;  4AXQ A;  1CIZ A;  5I4O A;  3LJZ A;  2PJT A;  5D1U A;  4JIJ A;  4GWN A;  3LIL A;  1FLS A;  3LMC A;  5L7F A;  3ZUK A;  4PKV A;  1G49 A;  1XUC A;  1UMT A;  2ERQ A;  3HY7 A;  3LEA A;  4JA1 A;  3HBU P;  3VI1 A;  4PKU A;  1JAN A;  966C A;  2JSD A;  3LGP A;  3G42 A;  3MA2 A;  1OM6 A;  1S4B P;  2OVZ A;  1ZP5 A;  5CZM A;  5BOY A;  3CKI A;  1BKC E;  1HOV A;  5D1S A;  1XUR A;  4I35 A;  2OY2 A;  1JIW P;  1JKY A;  1R55 A;  1C7K A;  1J7N A;  2X3B A;  3L0T A;  1HV5 A;  1IAE A;  2W12 A;  3EDH A;  5CXA A;  4L63 A;  1GXD A;  4L19 A;  3O2X A;  1ZXC A;  5I2Z A;  4FXY P;  1OS9 A;  4WZV A;  3U1R A;  2FV5 A;  1JK3 A;  2Y6D A;  4DV8 A;  1D8M A;  1GKC A;  1G05 A;  4XM7 A;  3Q2G A;  1QJI A;  1MNC A;  4JQG A;  3B8Z A;  3LK8 A;  3Q2H A;  3K7N A;  4WF6 A;  4GR3 A;  5I0L A;  1Q3A A;  3NX7 A;  2E2D A;  1CXV A;  1MMB A;  1XFU A;  3F18 A;  1OM8 A;  1B3D A;  4XCT A;  3LJT A;  5B5P A;  1G4K A;  1MMQ A;  1IAG A;  4J4M A;  2ERP A;  2DDF A;  4A7B A;  1QJJ A;  4AUO A;  1QIB A;  1OMJ A;  2D1O A;  1JAP A;  3LE9 A;  1DMT A;  2MLS A;  2JNP A;  3KME A;  1ZTQ A;  3P1V A;  2YB9 A;  3TS4 A;  1IAB A;  2E3X A;  2WOA A;  1JAO A;  4H3X A;  2JT6 A;  4PKW A;  4XM8 A;  4H84 A;  4IN9 A;  1B8Y A;  3I7I A;  2W0D A;  3KEC A;  1K7G A;  1JH1 A;  1RMZ A;  3F19 A;  1A85 A;  1YQY A;  2DW1 A;  4H76 A;  1JAQ A;  1BKC A;  4DF9 A;  5CUH A;  3L0V A;  1BQO A;  1Z3J A;  4GWM A;  1K7Q A;  1XUD A;  1JIZ A;  4L6T A;  1OM7 A;  1R1H A;  1O0T A;  2MLR A;  1PWW A;  3LUM A;  1KBC A;  1PWU A;  5BOT A;  3F15 A;  1D8F A;  2AIG P;  5I12 A;  1BM6 A;  2OW9 A;  4FXQ A;  4EFS A;  1SRP A;  1CK7 A;  1G9K A;  1XFV A;  2USN A;  4PKR A;  3VTG A;  1FBL A;  1XFX A;  1KUH A;  1UTZ A;  2V4B A;  2FV9 A;  2Y6C A;  456C A;  3WV2 A;  3DL1 A;  1EUB A;  3KHI A;  3DPF A;  3EHX A;  3HBV P;  4JP4 A;  2TCL A;  3EWJ A;  1SAT A;  2X3A A;  2W14 A;  4A3W A;  2OW1 A;  1ATL A;  3HB2 P;  5L79 A;  2J0T A;  4H82 A;  2JIH A;  2WO9 A;  4H49 A;  4WKI A;  2YIG A;  3HDB A;  3LUN A;  1O0Q A;  1BZS A;  4HMA A;  1D5J A;  4IUW A;  1YCM A;  3O64 A;  1GE6 A;  1YP1 A;  1IAD A;  3LIK A;  1G12 A;  2O3E A;  1FM1 A;  4DD8 A;  2I47 A;  2D1N A;  1GKD A;  3TSK A;  1GE5 A;  4GUY A;  4I03 A;  3V96 B;  2J83 A;  5BPA A;  2K9C A;  3HY9 A;  4PKQ A;  1PWP A;  1KUK A;  1WNI A;  4H2E A;  2O36 A;  3AIG A;  3G5C A;  1YOU A;  1SLM A;  1SLN A;  3LQ0 A;  5D2B A;  4XM6 A;  1CAQ A;  3ZXH A;  3ZVS A;  1KUG A;  5I3M A;  3K7L A;  2L0R A;  2POJ A;  2OXW A;  3LJG A;  3N2V A;  4CTH A;  1AKL A;  4PKS A;  3WV3 A;  4JPA A;  3E8R A;  1OO9 A;  3USN A;  3EDI A;  3HYG A;  3RTS A;  3KEK A;  5JMY A;  1KAP P;  4H30 A;  1BIW A;  3F1A A;  2OW0 A;  2OXZ A;  2OXU A;  1Y8J A;  1MMR A;  2SRT A;  1D7X A;  1I73 A;  2KRJ A;  3I7G A;  2A8H A;  4ZR5 A;  3DWB A;  3EHY A;  1IAA A;  4FU4 A;  1DTH A;  2OI0 A;  1AF0 A;  3KWV C;  2Z2D A;  1HFC A;  2CLT A;  2XS3 A;  1QIA A;  1BSW A;  1EAK A;  1ROS A;  3LIR A;  3LKA A;  5LAB A;  4DPE A;  3EDZ A;  1R54 A;  3BA0 A;  1USN A;  2HU6 A;  1IAC A;  2JT5 A;  4GF1 A;  3ELM A;  1BUV M;  1UMS A;  1Y0V A;  3EDG A;  2RJQ A;  2OW2 A;  1PWQ A;  2WO8 A;  3RTT A;  1SMP A;  4XBH A;  1Y93 A;  1C8T A;  3DSL A;  1HFS A;  3OHL A;  5I43 A;  2CKI A;  4WK7 A;  2XS4 A;  4AIG A;  1OS2 A;  1CQR A;  4WKE A;  5D1T A;  1XFW A;  2RJP A;  4IJO A;  4FVL A;  3TT4 A;  3SHI A;  1K7I A;  1CGL A;  1GE7 A;  1XFZ A;  1BKC I;  3DNG A;  5B5O A;  2N8R A;  1AST A;  2X7M A;  1UEA A;  1CGF A;  3B92 A;  1ZVX A;  1HTD A;  2DW0 A;  3N2U A;  2K2G A;  4Q1L A;  2MZI A;  3UVC A;  2X3C A;  4ON1 A;  1AYK A;  4ILW D;  4R3V A;  3P24 A;  3DPE A;  3WV1 A;  1BQQ M;  2OZR A;  1GO8 P;  1I1I P;  4QKZ A;  1I76 A;  1SU3 A;  3LQB A;  4HX3 A;  1R1J A;  830C A;  1ND1 A;  3F17 A;  4PKT A;  1MMP A;  4AYK A;  1KUI A;  4G9L A;  1CGE A;  1L6J A;  2DDY A;  1EB6 A;  2OY4 A;  1XFY A;  1KUF A;  1A86 A;  1GO7 P;  3GBO A;  1QIC A;  3OHO A;  2DW2 A;  3F16 A;  3TVC A;  1C3I A;  1UTT A;  1R1I A;  5D7W A;  5H8X A;  1BUD A;  1JJ9 A;  1H71 P;  1ZXV A;  3KMC A;  2MZE A;  3KRY A;  2MZH A;  4GQL A;  4H1Q A;  2ERO A;  2OVX A;  2W15 A;  5D3C A;  1ZS0 A;  4G0D A;  2QPJ A;  3AYU A;  4GR0 A; 
#chains in the Genus database with same CATH topology
 1RM8 A;  1PWV A;  2W13 A;  3AYK A;  4GR8 A;  1QUA A;  1HY7 A;  3KEJ A;  2AYK A;  3B2Z A;  3HDA P;  4L7A A;  1CIZ A;  4AXQ A;  5I4O A;  3LJZ A;  2PJT A;  5D1U A;  4JIJ A;  4GWN A;  3LIL A;  1FLS A;  3LMC A;  5L7F A;  3ZUK A;  4PKV A;  3DTI A;  1G49 A;  1XUC A;  1UMT A;  2ERQ A;  3HY7 A;  3LEA A;  4JA1 A;  3HBU P;  3VI1 A;  4PKU A;  1JAN A;  966C A;  2JSD A;  3LGP A;  3G42 A;  3MA2 A;  1OM6 A;  1S4B P;  2OVZ A;  1ZP5 A;  5CZM A;  5BOY A;  3CKI A;  1BKC E;  1HOV A;  5D1S A;  1XUR A;  4I35 A;  2OY2 A;  1JIW P;  1JKY A;  1R55 A;  1C7K A;  1J7N A;  2X3B A;  3L0T A;  1HV5 A;  1IAE A;  2W12 A;  3EDH A;  5CXA A;  4L63 A;  1GXD A;  4L19 A;  3O2X A;  1ZXC A;  5I2Z A;  4FXY P;  1OS9 A;  4WZV A;  3U1R A;  2FV5 A;  1JK3 A;  2Y6D A;  4DV8 A;  3DTK A;  1D8M A;  1GKC A;  1G05 A;  4XM7 A;  3Q2G A;  1QJI A;  1MNC A;  4JQG A;  3B8Z A;  3LK8 A;  3Q2H A;  3K7N A;  4WF6 A;  4GR3 A;  5I0L A;  1Q3A A;  3NX7 A;  2E2D A;  1CXV A;  1MMB A;  1XFU A;  3F18 A;  1OM8 A;  1B3D A;  4XCT A;  3LJT A;  5B5P A;  1G4K A;  1MMQ A;  1IAG A;  4J4M A;  2ERP A;  2DDF A;  4A7B A;  1QJJ A;  4AUO A;  1QIB A;  1OMJ A;  2D1O A;  1JAP A;  3LE9 A;  1DMT A;  2MLS A;  2JNP A;  3KME A;  1ZTQ A;  3P1V A;  2YB9 A;  3TS4 A;  1IAB A;  2E3X A;  2WOA A;  1JAO A;  4H3X A;  2JT6 A;  4PKW A;  4XM8 A;  4H84 A;  4IN9 A;  1B8Y A;  3I7I A;  2W0D A;  3KEC A;  1K7G A;  1JH1 A;  1RMZ A;  3F19 A;  1A85 A;  1YQY A;  2DW1 A;  4H76 A;  1JAQ A;  1BKC A;  4DF9 A;  5CUH A;  3L0V A;  1BQO A;  1Z3J A;  4GWM A;  1K7Q A;  1XUD A;  1JIZ A;  4L6T A;  1OM7 A;  1R1H A;  1O0T A;  2MLR A;  1PWW A;  3LUM A;  1KBC A;  1PWU A;  5BOT A;  3F15 A;  1D8F A;  2AIG P;  5I12 A;  1BM6 A;  2OW9 A;  4FXQ A;  4EFS A;  1SRP A;  1CK7 A;  1G9K A;  1XFV A;  2USN A;  4PKR A;  3VTG A;  1FBL A;  1XFX A;  1KUH A;  1UTZ A;  2V4B A;  2FV9 A;  2Y6C A;  456C A;  3WV2 A;  3DL1 A;  1EUB A;  3KHI A;  3DPF A;  3EHX A;  3HBV P;  4JP4 A;  2TCL A;  3EWJ A;  1SAT A;  2X3A A;  2W14 A;  4A3W A;  2OW1 A;  1ATL A;  3HB2 P;  5L79 A;  2J0T A;  4H82 A;  2JIH A;  2WO9 A;  4H49 A;  4WKI A;  2YIG A;  3HDB A;  3LUN A;  1O0Q A;  1BZS A;  4HMA A;  1D5J A;  4IUW A;  1YCM A;  3O64 A;  1GE6 A;  1YP1 A;  1IAD A;  3LIK A;  1G12 A;  2O3E A;  1FM1 A;  4DD8 A;  2I47 A;  2D1N A;  1GKD A;  3TSK A;  1GE5 A;  4GUY A;  4I03 A;  3V96 B;  2J83 A;  5BPA A;  2K9C A;  3HY9 A;  4PKQ A;  1PWP A;  1TVI A;  1KUK A;  1WNI A;  4H2E A;  2O36 A;  3AIG A;  3G5C A;  1YOU A;  1SLM A;  1SLN A;  3LQ0 A;  5D2B A;  4XM6 A;  1CAQ A;  3ZXH A;  3ZVS A;  1KUG A;  5I3M A;  3K7L A;  2L0R A;  2POJ A;  2OXW A;  3LJG A;  3N2V A;  4CTH A;  1AKL A;  4PKS A;  3WV3 A;  4JPA A;  3E8R A;  1OO9 A;  3USN A;  3EDI A;  3HYG A;  3RTS A;  3KEK A;  5JMY A;  1KAP P;  4H30 A;  1BIW A;  3F1A A;  2OW0 A;  2OXZ A;  2OXU A;  1Y8J A;  1MMR A;  2SRT A;  1D7X A;  1I73 A;  2KRJ A;  3I7G A;  2A8H A;  4ZR5 A;  3DTE A;  3DWB A;  3EHY A;  1IAA A;  4FU4 A;  1DTH A;  2OI0 A;  1AF0 A;  3KWV C;  2Z2D A;  1HFC A;  2CLT A;  2XS3 A;  1QIA A;  1BSW A;  1EAK A;  1ROS A;  3LIR A;  3LKA A;  5LAB A;  4DPE A;  3EDZ A;  1R54 A;  3BA0 A;  1OZ9 A;  1USN A;  2HU6 A;  1IAC A;  2JT5 A;  4GF1 A;  3ELM A;  1BUV M;  1UMS A;  1Y0V A;  3EDG A;  2RJQ A;  2OW2 A;  1PWQ A;  2WO8 A;  3RTT A;  1SMP A;  4XBH A;  1Y93 A;  1C8T A;  3DSL A;  1HFS A;  3OHL A;  5I43 A;  2CKI A;  4WK7 A;  2XS4 A;  4AIG A;  1OS2 A;  1CQR A;  1XM5 A;  4WKE A;  5D1T A;  1XFW A;  2RJP A;  4IJO A;  4FVL A;  3TT4 A;  3SHI A;  1K7I A;  1CGL A;  1GE7 A;  1XFZ A;  1BKC I;  3DNG A;  5B5O A;  2N8R A;  1AST A;  2X7M A;  1UEA A;  1CGF A;  3B92 A;  1ZVX A;  1HTD A;  2DW0 A;  3N2U A;  2K2G A;  4Q1L A;  2MZI A;  3UVC A;  2X3C A;  4ON1 A;  1AYK A;  4ILW D;  4R3V A;  3P24 A;  3DPE A;  3WV1 A;  1BQQ M;  2OZR A;  1GO8 P;  1I1I P;  4QKZ A;  1I76 A;  1SU3 A;  3LQB A;  4HX3 A;  1R1J A;  830C A;  1ND1 A;  1XAX A;  3F17 A;  4PKT A;  1MMP A;  4AYK A;  1KUI A;  4G9L A;  1CGE A;  1L6J A;  2DDY A;  1EB6 A;  2OY4 A;  1XFY A;  1KUF A;  1A86 A;  1GO7 P;  3GBO A;  1QIC A;  3OHO A;  2DW2 A;  3F16 A;  3TVC A;  2YUF A;  1C3I A;  1UTT A;  1R1I A;  5D7W A;  5H8X A;  1BUD A;  1JJ9 A;  1H71 P;  1ZXV A;  3KMC A;  2MZE A;  3KRY A;  2MZH A;  4GQL A;  4H1Q A;  2ERO A;  2OVX A;  2W15 A;  5D3C A;  1ZS0 A;  4G0D A;  2QPJ A;  3AYU A;  4GR0 A; 
#chains in the Genus database with same CATH homology
 1RM8 A;  1PWV A;  2W13 A;  3AYK A;  4GR8 A;  1QUA A;  1HY7 A;  3KEJ A;  2AYK A;  3B2Z A;  3HDA P;  4L7A A;  1CIZ A;  4AXQ A;  5I4O A;  3LJZ A;  2PJT A;  5D1U A;  4JIJ A;  4GWN A;  3LIL A;  1FLS A;  3LMC A;  5L7F A;  3ZUK A;  4PKV A;  3DTI A;  1G49 A;  1XUC A;  1UMT A;  2ERQ A;  3HY7 A;  3LEA A;  4JA1 A;  3HBU P;  3VI1 A;  4PKU A;  1JAN A;  966C A;  2JSD A;  3LGP A;  3G42 A;  3MA2 A;  1OM6 A;  1S4B P;  2OVZ A;  1ZP5 A;  5CZM A;  5BOY A;  3CKI A;  1BKC E;  1HOV A;  5D1S A;  1XUR A;  4I35 A;  2OY2 A;  1JIW P;  1JKY A;  1R55 A;  1C7K A;  1J7N A;  2X3B A;  3L0T A;  1HV5 A;  1IAE A;  2W12 A;  3EDH A;  5CXA A;  4L63 A;  1GXD A;  4L19 A;  3O2X A;  1ZXC A;  5I2Z A;  4FXY P;  1OS9 A;  4WZV A;  3U1R A;  2FV5 A;  1JK3 A;  2Y6D A;  4DV8 A;  3DTK A;  1D8M A;  1GKC A;  1G05 A;  4XM7 A;  3Q2G A;  1QJI A;  1MNC A;  4JQG A;  3B8Z A;  3LK8 A;  3Q2H A;  3K7N A;  4WF6 A;  4GR3 A;  5I0L A;  1Q3A A;  3NX7 A;  2E2D A;  1CXV A;  1MMB A;  1XFU A;  3F18 A;  1OM8 A;  1B3D A;  4XCT A;  3LJT A;  5B5P A;  1G4K A;  1MMQ A;  1IAG A;  4J4M A;  2ERP A;  2DDF A;  4A7B A;  1QJJ A;  4AUO A;  1QIB A;  1OMJ A;  2D1O A;  1JAP A;  3LE9 A;  1DMT A;  2MLS A;  2JNP A;  3KME A;  1ZTQ A;  3P1V A;  2YB9 A;  3TS4 A;  1IAB A;  2E3X A;  2WOA A;  1JAO A;  4H3X A;  2JT6 A;  4PKW A;  4XM8 A;  4H84 A;  4IN9 A;  1B8Y A;  3I7I A;  2W0D A;  3KEC A;  1K7G A;  1JH1 A;  1RMZ A;  3F19 A;  1A85 A;  1YQY A;  2DW1 A;  4H76 A;  1JAQ A;  1BKC A;  4DF9 A;  5CUH A;  3L0V A;  1BQO A;  1Z3J A;  4GWM A;  1K7Q A;  1XUD A;  1JIZ A;  4L6T A;  1OM7 A;  1R1H A;  1O0T A;  2MLR A;  1PWW A;  3LUM A;  1KBC A;  1PWU A;  5BOT A;  3F15 A;  1D8F A;  2AIG P;  5I12 A;  1BM6 A;  2OW9 A;  4FXQ A;  4EFS A;  1SRP A;  1CK7 A;  1G9K A;  1XFV A;  2USN A;  4PKR A;  3VTG A;  1FBL A;  1XFX A;  1KUH A;  1UTZ A;  2V4B A;  2FV9 A;  2Y6C A;  456C A;  3WV2 A;  3DL1 A;  1EUB A;  3KHI A;  3DPF A;  3EHX A;  3HBV P;  4JP4 A;  2TCL A;  3EWJ A;  1SAT A;  2X3A A;  2W14 A;  4A3W A;  2OW1 A;  1ATL A;  3HB2 P;  5L79 A;  2J0T A;  4H82 A;  2JIH A;  2WO9 A;  4H49 A;  4WKI A;  2YIG A;  3HDB A;  3LUN A;  1O0Q A;  1BZS A;  4HMA A;  1D5J A;  4IUW A;  1YCM A;  3O64 A;  1GE6 A;  1YP1 A;  1IAD A;  3LIK A;  1G12 A;  2O3E A;  1FM1 A;  4DD8 A;  2I47 A;  2D1N A;  1GKD A;  3TSK A;  1GE5 A;  4GUY A;  4I03 A;  3V96 B;  2J83 A;  5BPA A;  2K9C A;  3HY9 A;  4PKQ A;  1PWP A;  1KUK A;  1WNI A;  4H2E A;  2O36 A;  3AIG A;  3G5C A;  1YOU A;  1SLM A;  1SLN A;  3LQ0 A;  5D2B A;  4XM6 A;  1CAQ A;  3ZXH A;  3ZVS A;  1KUG A;  5I3M A;  3K7L A;  2L0R A;  2POJ A;  2OXW A;  3LJG A;  3N2V A;  4CTH A;  1AKL A;  4PKS A;  3WV3 A;  4JPA A;  3E8R A;  1OO9 A;  3USN A;  3EDI A;  3HYG A;  3RTS A;  3KEK A;  5JMY A;  1KAP P;  4H30 A;  1BIW A;  3F1A A;  2OW0 A;  2OXZ A;  2OXU A;  1Y8J A;  1MMR A;  2SRT A;  1D7X A;  1I73 A;  2KRJ A;  3I7G A;  2A8H A;  4ZR5 A;  3DTE A;  3DWB A;  3EHY A;  1IAA A;  4FU4 A;  1DTH A;  2OI0 A;  1AF0 A;  3KWV C;  2Z2D A;  1HFC A;  2CLT A;  2XS3 A;  1QIA A;  1BSW A;  1EAK A;  1ROS A;  3LIR A;  3LKA A;  5LAB A;  4DPE A;  3EDZ A;  1R54 A;  3BA0 A;  1USN A;  2HU6 A;  1IAC A;  2JT5 A;  4GF1 A;  3ELM A;  1BUV M;  1UMS A;  1Y0V A;  3EDG A;  2RJQ A;  2OW2 A;  1PWQ A;  2WO8 A;  3RTT A;  1SMP A;  4XBH A;  1Y93 A;  1C8T A;  3DSL A;  1HFS A;  3OHL A;  5I43 A;  2CKI A;  4WK7 A;  2XS4 A;  4AIG A;  1OS2 A;  1CQR A;  4WKE A;  5D1T A;  1XFW A;  2RJP A;  4IJO A;  4FVL A;  3TT4 A;  3SHI A;  1K7I A;  1CGL A;  1GE7 A;  1XFZ A;  1BKC I;  3DNG A;  5B5O A;  2N8R A;  1AST A;  2X7M A;  1UEA A;  1CGF A;  3B92 A;  1ZVX A;  1HTD A;  2DW0 A;  3N2U A;  2K2G A;  4Q1L A;  2MZI A;  3UVC A;  2X3C A;  4ON1 A;  1AYK A;  4ILW D;  4R3V A;  3P24 A;  3DPE A;  3WV1 A;  1BQQ M;  2OZR A;  1GO8 P;  1I1I P;  4QKZ A;  1I76 A;  1SU3 A;  3LQB A;  4HX3 A;  1R1J A;  830C A;  1ND1 A;  3F17 A;  4PKT A;  1MMP A;  4AYK A;  1KUI A;  4G9L A;  1CGE A;  1L6J A;  2DDY A;  1EB6 A;  2OY4 A;  1XFY A;  1KUF A;  1A86 A;  1GO7 P;  3GBO A;  1QIC A;  3OHO A;  2DW2 A;  3F16 A;  3TVC A;  2YUF A;  1C3I A;  1UTT A;  1R1I A;  5D7W A;  5H8X A;  1BUD A;  1JJ9 A;  1H71 P;  1ZXV A;  3KMC A;  2MZE A;  3KRY A;  2MZH A;  4GQL A;  4H1Q A;  2ERO A;  2OVX A;  2W15 A;  5D3C A;  1ZS0 A;  4G0D A;  2QPJ A;  3AYU A;  4GR0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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