1JOLA

The crystal structure of the binary complex between folinic acid (leucovorin) and e. coli dihydrofolate reductase
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
159
structure length
159
Chain Sequence
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLDKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of Escherichia coli dihydrofolate reductase complexed with 5-formyltetrahydrofolate (folinic acid) in two space groups: evidence for enolization of pteridine O4.
pubmed doi rcsb
molecule keywords DIHYDROFOLATE REDUCTASE
molecule tags Oxidoreductase
total genus 45
structure length 159
sequence length 159
chains with identical sequence B
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 1996-02-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 1jolA00
3QG2A 1S3UA 1LUDA 3FL8A 2W9SA 4XT6A 3DFRA 5EAJA 3SRUX 4PTHA 3FY9X 4H98A 2BLAA 1RX7A 3QLYA 4EJ1A 4IXFX 4ELBA 2HM9A 2W3MA 3FQVA 1KMVA 3QFXA 1DR2A 3M09A 3NZ9X 3FRBX 3TD8A 1DRAA 3NTZA 1HFRA 1RX3A 3DL6A 4ELFA 1CD2A 3FRFX 4LAEX 4EIGA 1RA2A 4Q0EA 5U27A 1YHOA 4H95A 3FRDX 3R33A 4PTJA 2INQA 4P3RA 1RA1A 1RH3A 4KL9A 3KJRA 3TQAA 3ZPGA 1RA9A 2C2SA 4QLEA 4KM0A 1S3VA 3NXOA 3JTWA 4QLGA 3DGAA 2G6VA 3NXTA 5HSUA 1AOEA 3OAFA 3EIGA 1VJ3A 4HOGA 3E0BA 2OIPA 4NX7A 2W3VA 3F0VX 3NZDA 4I13A 2D5NA 4NX6A 4Q67A 4KYAA 3IROA 3QL0A 4KAKA 3K2HA 3HJ3A 4EILA 1CZ3A 3KY8A 3EEMA 5DXVA 3SRWX 3TQ9A 3S9UA 1DYIA 2FZJA 4KBNA 4KY4A 3L3RA 1DYRA 1J3KA 1DHIA 4Q0DA 5JA3A 3QLRA 3IX9A 2QK8A 5E8QA 2ZZAA 5HQYA 4PSYA 2HXVA 3SRRX 3QLWA 3JW5A 4DPHA 1DHFA 2CIGA 2C2TA 1J3IA 3EX8A 1RG7A 1M78A 2AZNA 1U72A 3SR5X 1DYHA 8DFRA 1M79A 1MVTA 1U70A 4ECKA 2W9HA 3F0QX 4ELEA 1DRFA 3QYOA 3FQ0A 4EIZA 3EEJA 2ITHA 1DYJA 2OBCA 3I3RA 4ELGA 3GYFA 1DF7A 3FREX 3SRQX 3QLXA 3D84X 4KLXA 1VDRA 3NZAX 1RB2A 3K47A 3CLBA 4M2XA 4XT4A 1RC4A 4IXED 3F0SX 3FQFA 1RD7A 3GHVA 1IA4A 4QI9A 4QHVA 3KFYA 3K45A 4DDRA 4DPDA 2JYBA 4P3QA 3UM6A 1IA2A 4DFRA 1E26A 1BOZA 3K74A 3KGYA 7DFRA 1J3JA 4FHBA 1RA3A 4X5IA 2FZIA 4KY8A 1JOLA 1OHJA 4KD7A 1U71A 1RX2A 1RX5A 3FS6A 1PDBA 1SEJA 4XT5A 5HVBA 3GHCA 4LAHX 2DHFA 1DHJA 4PSTA 4FGGA 1DR6A 3SRSX 1D1GA 1DG7A 3FYVX 4HOFA 1DDSA 1AI9A 3IA5A 5U26A 4LAGX 1M7AA 1BZFA 2CD2A 4XT8A 4QJZD 4DP3A 1S3WA 1KLKA 3QLZA 3F8ZA 1KMSA 1LY3A 3D80A 2HQPA 4CD2A 3QL3A 3CD2A 3NZ6X 1RX6A 1DLRA 4QJCA 2P4GA 4PDJA 3CSEA 3ROAA 3S3VA 1DR1A 3NRRA 4KEBA 4RGCA 3FY8X 2D0KA 4XE6X 5HT4A 2BL9A 2L28A 4OR7A 2LF1A 3JWFA 1LY4A 1RF7A 1IA1A 3M08A 5ECCA 3F0UX 3IRMA 1QZFA 3QYLA 4KFJA 3RO9A 3UM5A 4G3MA 3NU0A 1DLSA 1RE7A 2ANQA 1DG5A 4FGHA 4XRBA 4GH8A 3SGYA 3EEKA 3SAIA 5HVEA 3NZBX 3GI2A 5HI6A 5HSRA 4M7UA 1HFQA 3JSUA 3NXVA 4I1NA 2W9TA 5HF0X 1DR4A 4LEKX 2W3BA 1OHKA 1DREA 3IRNA 4M7VA 1JOMA 3F91A 3QLSA 3IA4A 1RA8A 5JG0X 4KJLA 1RB3A 3KJSA 4H96A 2W3WA 4M6KA 3DRCA 1DRBA 5ECXA 3F0XX 3CL9A 1RX4A 5CCCA 3ZPCA 3JWMA 1RX9A 2W3AA 1HFPA 3FQCA 3SQYX 4X5JA 2BLCA 3FYWX 5HT5A 3JW3A 2O7PA 3F8YA 5FDAA 1ZDRA 3NZCX 4X5HA 2FZHA 4M6JA 3NXYA 4HA7A 3FL9A 3LG4A 3GHWA 4OSGA 4M6LA 4KNEA 4X5GA 3SA2A 2ANOA 2GD9A 2BLBA 1TDRA 4HA9A 3QGTA 3UM8A 6DFRA 2W9GA 4P66A 3JVXA 4KJJA 3JWCA 4KJKA 3I8AX 4XECX 4G8ZX 2H2QA 3JWKA 2DRCA 3OCHA 3SA1A 4KM2A 3RG9A 1DISA 3F0BX 2XW7A 3EELA 5HF2X 3DAUA 3FQZA 1IA3A 3FQOA 3DL5A 3INVA 1S3YA 4Q6AA 4G95A 1DR7A 3DATA 5CC9A 5HUIA 4XT7A 1PD9A 4IXGX 1DR5A 3HBBA 3NXXA 1RX8A 4X5FA 3VCOA 3TQ8A 4PSSA 5DFRA 1DRHA 3NXRA 2KGKA 4HOEA 1DAJA 1PD8A 3TQBA 3SH2A 3Q1HA 1MVSA 3DG8A 4QLFA 4ELHA 1JUVA 5HQZA 3S7AA 1DG8A 5HPBA 4TU5X 4P68A 1DR3A 1AO8A 1DIUA 1RX1A 3N0HA 3FRAX 4H97A 2B3ZA 1DDRA
chains in the Genus database with same CATH superfamily
3QG2A 1S3UA 1LUDA 3FL8A 2W9SA 4XT6A 3DFRA 5EAJA 3SRUX 4PTHA 3FY9X 4H98A 2BLAA 1RX7A 3QLYA 4EJ1A 4IXFX 4ELBA 2HM9A 2W3MA 3FQVA 1KMVA 3QFXA 1DR2A 3M09A 3NZ9X 3FRBX 3TD8A 1DRAA 3NTZA 1HFRA 1RX3A 3DL6A 4ELFA 1CD2A 3FRFX 4LAEX 4EIGA 1RA2A 4Q0EA 5U27A 1YHOA 4H95A 3FRDX 3R33A 4PTJA 2INQA 4P3RA 1RA1A 1RH3A 4KL9A 3KJRA 3TQAA 3ZPGA 1RA9A 2C2SA 4QLEA 4KM0A 1S3VA 3NXOA 3JTWA 4QLGA 3DGAA 2G6VA 3NXTA 5HSUA 1AOEA 3OAFA 3EIGA 1VJ3A 4HOGA 3E0BA 2OIPA 4NX7A 2W3VA 3F0VX 3NZDA 4I13A 2D5NA 4NX6A 4Q67A 4KYAA 3IROA 3QL0A 4KAKA 3K2HA 3HJ3A 4EILA 1CZ3A 3KY8A 3EEMA 5DXVA 3SRWX 3TQ9A 3S9UA 1DYIA 2FZJA 4KBNA 4KY4A 3L3RA 1DYRA 1J3KA 1DHIA 4Q0DA 5JA3A 3QLRA 3IX9A 2QK8A 5E8QA 2ZZAA 5HQYA 4PSYA 2HXVA 3SRRX 3QLWA 3JW5A 4DPHA 1DHFA 2CIGA 2C2TA 1J3IA 3EX8A 1RG7A 1M78A 2AZNA 1U72A 3SR5X 1DYHA 8DFRA 1M79A 1MVTA 1U70A 4ECKA 2W9HA 3F0QX 4ELEA 1DRFA 3QYOA 3FQ0A 4EIZA 3EEJA 2ITHA 1DYJA 2OBCA 3I3RA 4ELGA 3GYFA 1DF7A 3FREX 3SRQX 3QLXA 3D84X 4KLXA 1VDRA 3NZAX 1RB2A 3K47A 3CLBA 4M2XA 4XT4A 1RC4A 4IXED 3F0SX 3FQFA 1RD7A 3GHVA 1IA4A 4QI9A 4QHVA 3KFYA 3K45A 4DDRA 4DPDA 2JYBA 4P3QA 3UM6A 1IA2A 4DFRA 1E26A 1BOZA 3K74A 3KGYA 7DFRA 1J3JA 4FHBA 1RA3A 4X5IA 2FZIA 4KY8A 1JOLA 1OHJA 4KD7A 1U71A 1RX2A 1RX5A 3FS6A 1PDBA 1SEJA 4XT5A 5HVBA 3GHCA 4LAHX 2DHFA 1DHJA 4PSTA 4FGGA 1DR6A 3SRSX 1D1GA 1DG7A 3FYVX 4HOFA 1DDSA 1AI9A 3IA5A 5U26A 4LAGX 1M7AA 1BZFA 2CD2A 4XT8A 4QJZD 4DP3A 1S3WA 1KLKA 3QLZA 3F8ZA 1KMSA 1LY3A 3D80A 2HQPA 4CD2A 3QL3A 3CD2A 3NZ6X 1RX6A 1DLRA 4QJCA 2P4GA 4PDJA 3CSEA 3ROAA 3S3VA 1DR1A 3NRRA 4KEBA 4RGCA 3FY8X 2D0KA 4XE6X 5HT4A 2BL9A 2L28A 4OR7A 2LF1A 3JWFA 1LY4A 1RF7A 1IA1A 3M08A 5ECCA 3F0UX 3IRMA 1QZFA 3QYLA 4KFJA 3RO9A 3UM5A 4G3MA 3NU0A 1DLSA 1RE7A 2ANQA 1DG5A 4FGHA 4XRBA 4GH8A 3SGYA 3EEKA 3SAIA 5HVEA 3NZBX 3GI2A 5HI6A 5HSRA 4M7UA 1HFQA 3JSUA 3NXVA 4I1NA 2W9TA 5HF0X 1DR4A 4LEKX 2W3BA 1OHKA 1DREA 3IRNA 4M7VA 1JOMA 3F91A 3QLSA 3IA4A 1RA8A 5JG0X 4KJLA 1RB3A 3KJSA 4H96A 2W3WA 4M6KA 3DRCA 1DRBA 5ECXA 3F0XX 3CL9A 1RX4A 5CCCA 3ZPCA 3JWMA 1RX9A 2W3AA 1HFPA 3FQCA 3SQYX 4X5JA 2BLCA 3FYWX 5HT5A 3JW3A 2O7PA 3F8YA 5FDAA 1ZDRA 3NZCX 4X5HA 2FZHA 4M6JA 3NXYA 4HA7A 3FL9A 3LG4A 3GHWA 4OSGA 4M6LA 4KNEA 4X5GA 3SA2A 2ANOA 2GD9A 2BLBA 1TDRA 4HA9A 3QGTA 3UM8A 6DFRA 2W9GA 4P66A 3JVXA 4KJJA 3JWCA 4KJKA 3I8AX 4XECX 4G8ZX 2H2QA 3JWKA 2DRCA 3OCHA 3SA1A 4KM2A 3RG9A 1DISA 3F0BX 2XW7A 3EELA 5HF2X 3DAUA 3FQZA 1IA3A 3FQOA 3DL5A 3INVA 1S3YA 4Q6AA 4G95A 1DR7A 3DATA 5CC9A 5HUIA 4XT7A 1PD9A 4IXGX 1DR5A 3HBBA 3NXXA 1RX8A 4X5FA 3VCOA 3TQ8A 4PSSA 5DFRA 1DRHA 3NXRA 2KGKA 4HOEA 1DAJA 1PD8A 3TQBA 3SH2A 3Q1HA 1MVSA 3DG8A 4QLFA 4ELHA 1JUVA 5HQZA 3S7AA 1DG8A 5HPBA 4TU5X 4P68A 1DR3A 1AO8A 1DIUA 1RX1A 3N0HA 3FRAX 4H97A 2B3ZA 1DDRA
chains in the Genus database with same CATH topology
3QG2A 1S3UA 1LUDA 3FL8A 2W9SA 4XT6A 3DFRA 5EAJA 3SRUX 4PTHA 3FY9X 4H98A 2BLAA 1RX7A 3QLYA 4EJ1A 4IXFX 4ELBA 2HM9A 2W3MA 3FQVA 1KMVA 3QFXA 1DR2A 3M09A 3NZ9X 3FRBX 3TD8A 1DRAA 3NTZA 1HFRA 1RX3A 3DL6A 4ELFA 1CD2A 3FRFX 4LAEX 4EIGA 1RA2A 4Q0EA 5U27A 1YHOA 4H95A 3FRDX 3R33A 4PTJA 2INQA 4P3RA 1RA1A 1RH3A 4KL9A 3KJRA 3TQAA 3ZPGA 1RA9A 2C2SA 4QLEA 4KM0A 1S3VA 3NXOA 3JTWA 4QLGA 3DGAA 2G6VA 3NXTA 5HSUA 1AOEA 3OAFA 3EIGA 1VJ3A 4HOGA 3E0BA 2OIPA 4NX7A 2W3VA 3F0VX 3NZDA 4I13A 2D5NA 4NX6A 4Q67A 4KYAA 3IROA 3QL0A 4KAKA 3K2HA 3HJ3A 4EILA 1CZ3A 3KY8A 3EEMA 5DXVA 3SRWX 3TQ9A 3S9UA 1DYIA 2FZJA 4KBNA 4KY4A 3L3RA 1DYRA 1J3KA 1DHIA 4Q0DA 5JA3A 3QLRA 3IX9A 2QK8A 5E8QA 2ZZAA 5HQYA 4PSYA 2HXVA 3SRRX 3QLWA 3JW5A 4DPHA 1DHFA 2CIGA 2C2TA 1J3IA 3EX8A 1RG7A 1M78A 2AZNA 1U72A 3SR5X 1DYHA 8DFRA 1M79A 1MVTA 1U70A 4ECKA 2W9HA 3F0QX 4ELEA 1DRFA 3QYOA 3FQ0A 4EIZA 3EEJA 2ITHA 1DYJA 2OBCA 3I3RA 4ELGA 3GYFA 1DF7A 3FREX 3SRQX 3QLXA 3D84X 4KLXA 1VDRA 3NZAX 1RB2A 3K47A 3CLBA 4M2XA 4XT4A 1RC4A 4IXED 3F0SX 3FQFA 1RD7A 3GHVA 1IA4A 4QI9A 4QHVA 3KFYA 3K45A 4DDRA 4DPDA 2JYBA 4P3QA 3UM6A 1IA2A 4DFRA 1E26A 1BOZA 3K74A 3KGYA 7DFRA 1J3JA 4FHBA 1RA3A 4X5IA 2FZIA 4KY8A 1JOLA 1OHJA 4KD7A 1U71A 1RX2A 1RX5A 3FS6A 1PDBA 1SEJA 4XT5A 5HVBA 3GHCA 4LAHX 2DHFA 1DHJA 4PSTA 4FGGA 1DR6A 3SRSX 1D1GA 1DG7A 3FYVX 4HOFA 1DDSA 1AI9A 3IA5A 5U26A 4LAGX 1M7AA 1BZFA 2CD2A 4XT8A 4QJZD 4DP3A 1S3WA 1KLKA 3QLZA 3F8ZA 1KMSA 1LY3A 3D80A 2HQPA 4CD2A 3QL3A 3CD2A 3NZ6X 1RX6A 1DLRA 4QJCA 2P4GA 4PDJA 3CSEA 3ROAA 3S3VA 1DR1A 3NRRA 4KEBA 4RGCA 3FY8X 2D0KA 4XE6X 5HT4A 2BL9A 2L28A 4OR7A 2LF1A 3JWFA 1LY4A 1RF7A 1IA1A 3M08A 5ECCA 3F0UX 3IRMA 1QZFA 3QYLA 4KFJA 3RO9A 3UM5A 4G3MA 3NU0A 1DLSA 1RE7A 2ANQA 1DG5A 4FGHA 4XRBA 4GH8A 3SGYA 3EEKA 3SAIA 5HVEA 3NZBX 3GI2A 5HI6A 5HSRA 4M7UA 1HFQA 3JSUA 3NXVA 4I1NA 2W9TA 5HF0X 1DR4A 4LEKX 2W3BA 1OHKA 1DREA 3IRNA 4M7VA 1JOMA 3F91A 3QLSA 3IA4A 1RA8A 5JG0X 4KJLA 1RB3A 3KJSA 4H96A 2W3WA 4M6KA 3DRCA 1DRBA 5ECXA 3F0XX 3CL9A 1RX4A 5CCCA 3ZPCA 3JWMA 1RX9A 2W3AA 1HFPA 3FQCA 3SQYX 4X5JA 2BLCA 3FYWX 5HT5A 3JW3A 2O7PA 3F8YA 5FDAA 1ZDRA 3NZCX 4X5HA 2FZHA 4M6JA 3NXYA 4HA7A 3FL9A 3LG4A 3GHWA 4OSGA 4M6LA 4KNEA 4X5GA 3SA2A 2ANOA 2GD9A 2BLBA 1TDRA 4HA9A 3QGTA 3UM8A 6DFRA 2W9GA 4P66A 3JVXA 4KJJA 3JWCA 4KJKA 3I8AX 4XECX 4G8ZX 2H2QA 3JWKA 2DRCA 3OCHA 3SA1A 4KM2A 3RG9A 1DISA 3F0BX 2XW7A 3EELA 5HF2X 3DAUA 3FQZA 1IA3A 3FQOA 3DL5A 3INVA 1S3YA 4Q6AA 4G95A 1DR7A 3DATA 5CC9A 5HUIA 4XT7A 1PD9A 4IXGX 1DR5A 3HBBA 3NXXA 1RX8A 4X5FA 3VCOA 3TQ8A 4PSSA 5DFRA 1DRHA 3NXRA 2KGKA 4HOEA 1DAJA 1PD8A 3TQBA 3SH2A 3Q1HA 1MVSA 3DG8A 4QLFA 4ELHA 1JUVA 5HQZA 3S7AA 1DG8A 5HPBA 4TU5X 4P68A 1DR3A 1AO8A 1DIUA 1RX1A 3N0HA 3FRAX 4H97A 2B3ZA 1DDRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QG2 A;  1S3U A;  1LUD A;  3FL8 A;  2W9S A;  4XT6 A;  3DFR A;  5EAJ A;  3SRU X;  4PTH A;  3FY9 X;  4H98 A;  2BLA A;  1RX7 A;  3QLY A;  4EJ1 A;  4IXF X;  4ELB A;  2HM9 A;  2W3M A;  3FQV A;  1KMV A;  3QFX A;  1DR2 A;  3M09 A;  3NZ9 X;  3FRB X;  3TD8 A;  1DRA A;  3NTZ A;  1HFR A;  1RX3 A;  3DL6 A;  4ELF A;  1CD2 A;  3FRF X;  4LAE X;  4EIG A;  1RA2 A;  4Q0E A;  5U27 A;  1YHO A;  4H95 A;  3FRD X;  3R33 A;  4PTJ A;  2INQ A;  4P3R A;  1RA1 A;  1RH3 A;  4KL9 A;  3KJR A;  3TQA A;  3ZPG A;  1RA9 A;  2C2S A;  4QLE A;  4KM0 A;  1S3V A;  3NXO A;  3JTW A;  4QLG A;  3DGA A;  2G6V A;  3NXT A;  5HSU A;  1AOE A;  3OAF A;  3EIG A;  1VJ3 A;  4HOG A;  3E0B A;  2OIP A;  4NX7 A;  2W3V A;  3F0V X;  3NZD A;  4I13 A;  2D5N A;  4NX6 A;  4Q67 A;  4KYA A;  3IRO A;  3QL0 A;  4KAK A;  3K2H A;  3HJ3 A;  4EIL A;  1CZ3 A;  3KY8 A;  3EEM A;  5DXV A;  3SRW X;  3TQ9 A;  3S9U A;  1DYI A;  2FZJ A;  4KBN A;  4KY4 A;  3L3R A;  1DYR A;  1J3K A;  1DHI A;  4Q0D A;  5JA3 A;  3QLR A;  3IX9 A;  2QK8 A;  5E8Q A;  2ZZA A;  5HQY A;  4PSY A;  2HXV A;  3SRR X;  3QLW A;  3JW5 A;  4DPH A;  1DHF A;  2CIG A;  2C2T A;  1J3I A;  3EX8 A;  1RG7 A;  1M78 A;  2AZN A;  1U72 A;  3SR5 X;  1DYH A;  8DFR A;  1M79 A;  1MVT A;  1U70 A;  4ECK A;  2W9H A;  3F0Q X;  4ELE A;  1DRF A;  3QYO A;  3FQ0 A;  4EIZ A;  3EEJ A;  2ITH A;  1DYJ A;  2OBC A;  3I3R A;  4ELG A;  3GYF A;  1DF7 A;  3FRE X;  3SRQ X;  3QLX A;  3D84 X;  4KLX A;  1VDR A;  3NZA X;  1RB2 A;  3K47 A;  3CLB A;  4M2X A;  4XT4 A;  1RC4 A;  4IXE D;  3F0S X;  3FQF A;  1RD7 A;  3GHV A;  1IA4 A;  4QI9 A;  4QHV A;  3KFY A;  3K45 A;  4DDR A;  4DPD A;  2JYB A;  4P3Q A;  3UM6 A;  1IA2 A;  4DFR A;  1E26 A;  1BOZ A;  3K74 A;  3KGY A;  7DFR A;  1J3J A;  4FHB A;  1RA3 A;  4X5I A;  2FZI A;  4KY8 A;  1JOL A;  1OHJ A;  4KD7 A;  1U71 A;  1RX2 A;  1RX5 A;  3FS6 A;  1PDB A;  1SEJ A;  4XT5 A;  5HVB A;  3GHC A;  4LAH X;  2DHF A;  1DHJ A;  4PST A;  4FGG A;  1DR6 A;  3SRS X;  1D1G A;  1DG7 A;  3FYV X;  4HOF A;  1DDS A;  1AI9 A;  3IA5 A;  5U26 A;  4LAG X;  1M7A A;  1BZF A;  2CD2 A;  4XT8 A;  4QJZ D;  4DP3 A;  1S3W A;  1KLK A;  3QLZ A;  3F8Z A;  1KMS A;  1LY3 A;  3D80 A;  2HQP A;  4CD2 A;  3QL3 A;  3CD2 A;  3NZ6 X;  1RX6 A;  1DLR A;  4QJC A;  2P4G A;  4PDJ A;  3CSE A;  3ROA A;  3S3V A;  1DR1 A;  3NRR A;  4KEB A;  4RGC A;  3FY8 X;  2D0K A;  4XE6 X;  5HT4 A;  2BL9 A;  2L28 A;  4OR7 A;  2LF1 A;  3JWF A;  1LY4 A;  1RF7 A;  1IA1 A;  3M08 A;  5ECC A;  3F0U X;  3IRM A;  1QZF A;  3QYL A;  4KFJ A;  3RO9 A;  3UM5 A;  4G3M A;  3NU0 A;  1DLS A;  1RE7 A;  2ANQ A;  1DG5 A;  4FGH A;  4XRB A;  4GH8 A;  3SGY A;  3EEK A;  3SAI A;  5HVE A;  3NZB X;  3GI2 A;  5HI6 A;  5HSR A;  4M7U A;  1HFQ A;  3JSU A;  3NXV A;  4I1N A;  2W9T A;  5HF0 X;  1DR4 A;  4LEK X;  2W3B A;  1OHK A;  1DRE A;  3IRN A;  4M7V A;  1JOM A;  3F91 A;  3QLS A;  3IA4 A;  1RA8 A;  5JG0 X;  4KJL A;  1RB3 A;  3KJS A;  4H96 A;  2W3W A;  4M6K A;  3DRC A;  1DRB A;  5ECX A;  3F0X X;  3CL9 A;  1RX4 A;  5CCC A;  3ZPC A;  3JWM A;  1RX9 A;  2W3A A;  1HFP A;  3FQC A;  3SQY X;  4X5J A;  2BLC A;  3FYW X;  5HT5 A;  3JW3 A;  2O7P A;  3F8Y A;  5FDA A;  1ZDR A;  3NZC X;  4X5H A;  2FZH A;  4M6J A;  3NXY A;  4HA7 A;  3FL9 A;  3LG4 A;  3GHW A;  4OSG A;  4M6L A;  4KNE A;  4X5G A;  3SA2 A;  2ANO A;  2GD9 A;  2BLB A;  1TDR A;  4HA9 A;  3QGT A;  3UM8 A;  6DFR A;  2W9G A;  4P66 A;  3JVX A;  4KJJ A;  3JWC A;  4KJK A;  3I8A X;  4XEC X;  4G8Z X;  2H2Q A;  3JWK A;  2DRC A;  3OCH A;  3SA1 A;  4KM2 A;  3RG9 A;  1DIS A;  3F0B X;  2XW7 A;  3EEL A;  5HF2 X;  3DAU A;  3FQZ A;  1IA3 A;  3FQO A;  3DL5 A;  3INV A;  1S3Y A;  4Q6A A;  4G95 A;  1DR7 A;  3DAT A;  5CC9 A;  5HUI A;  4XT7 A;  1PD9 A;  4IXG X;  1DR5 A;  3HBB A;  3NXX A;  1RX8 A;  4X5F A;  3VCO A;  3TQ8 A;  4PSS A;  5DFR A;  1DRH A;  3NXR A;  2KGK A;  4HOE A;  1DAJ A;  1PD8 A;  3TQB A;  3SH2 A;  3Q1H A;  1MVS A;  3DG8 A;  4QLF A;  4ELH A;  1JUV A;  5HQZ A;  3S7A A;  1DG8 A;  5HPB A;  4TU5 X;  4P68 A;  1DR3 A;  1AO8 A;  1DIU A;  1RX1 A;  3N0H A;  3FRA X;  4H97 A;  2B3Z A;  1DDR A; 
#chains in the Genus database with same CATH topology
 3QG2 A;  1S3U A;  1LUD A;  3FL8 A;  2W9S A;  4XT6 A;  3DFR A;  5EAJ A;  3SRU X;  4PTH A;  3FY9 X;  4H98 A;  2BLA A;  1RX7 A;  3QLY A;  4EJ1 A;  4IXF X;  4ELB A;  2HM9 A;  2W3M A;  3FQV A;  1KMV A;  3QFX A;  1DR2 A;  3M09 A;  3NZ9 X;  3FRB X;  3TD8 A;  1DRA A;  3NTZ A;  1HFR A;  1RX3 A;  3DL6 A;  4ELF A;  1CD2 A;  3FRF X;  4LAE X;  4EIG A;  1RA2 A;  4Q0E A;  5U27 A;  1YHO A;  4H95 A;  3FRD X;  3R33 A;  4PTJ A;  2INQ A;  4P3R A;  1RA1 A;  1RH3 A;  4KL9 A;  3KJR A;  3TQA A;  3ZPG A;  1RA9 A;  2C2S A;  4QLE A;  4KM0 A;  1S3V A;  3NXO A;  3JTW A;  4QLG A;  3DGA A;  2G6V A;  3NXT A;  5HSU A;  1AOE A;  3OAF A;  3EIG A;  1VJ3 A;  4HOG A;  3E0B A;  2OIP A;  4NX7 A;  2W3V A;  3F0V X;  3NZD A;  4I13 A;  2D5N A;  4NX6 A;  4Q67 A;  4KYA A;  3IRO A;  3QL0 A;  4KAK A;  3K2H A;  3HJ3 A;  4EIL A;  1CZ3 A;  3KY8 A;  3EEM A;  5DXV A;  3SRW X;  3TQ9 A;  3S9U A;  1DYI A;  2FZJ A;  4KBN A;  4KY4 A;  3L3R A;  1DYR A;  1J3K A;  1DHI A;  4Q0D A;  5JA3 A;  3QLR A;  3IX9 A;  2QK8 A;  5E8Q A;  2ZZA A;  5HQY A;  4PSY A;  2HXV A;  3SRR X;  3QLW A;  3JW5 A;  4DPH A;  1DHF A;  2CIG A;  2C2T A;  1J3I A;  3EX8 A;  1RG7 A;  1M78 A;  2AZN A;  1U72 A;  3SR5 X;  1DYH A;  8DFR A;  1M79 A;  1MVT A;  1U70 A;  4ECK A;  2W9H A;  3F0Q X;  4ELE A;  1DRF A;  3QYO A;  3FQ0 A;  4EIZ A;  3EEJ A;  2ITH A;  1DYJ A;  2OBC A;  3I3R A;  4ELG A;  3GYF A;  1DF7 A;  3FRE X;  3SRQ X;  3QLX A;  3D84 X;  4KLX A;  1VDR A;  3NZA X;  1RB2 A;  3K47 A;  3CLB A;  4M2X A;  4XT4 A;  1RC4 A;  4IXE D;  3F0S X;  3FQF A;  1RD7 A;  3GHV A;  1IA4 A;  4QI9 A;  4QHV A;  3KFY A;  3K45 A;  4DDR A;  4DPD A;  2JYB A;  4P3Q A;  3UM6 A;  1IA2 A;  4DFR A;  1E26 A;  1BOZ A;  3K74 A;  3KGY A;  7DFR A;  1J3J A;  4FHB A;  1RA3 A;  4X5I A;  2FZI A;  4KY8 A;  1JOL A;  1OHJ A;  4KD7 A;  1U71 A;  1RX2 A;  1RX5 A;  3FS6 A;  1PDB A;  1SEJ A;  4XT5 A;  5HVB A;  3GHC A;  4LAH X;  2DHF A;  1DHJ A;  4PST A;  4FGG A;  1DR6 A;  3SRS X;  1D1G A;  1DG7 A;  3FYV X;  4HOF A;  1DDS A;  1AI9 A;  3IA5 A;  5U26 A;  4LAG X;  1M7A A;  1BZF A;  2CD2 A;  4XT8 A;  4QJZ D;  4DP3 A;  1S3W A;  1KLK A;  3QLZ A;  3F8Z A;  1KMS A;  1LY3 A;  3D80 A;  2HQP A;  4CD2 A;  3QL3 A;  3CD2 A;  3NZ6 X;  1RX6 A;  1DLR A;  4QJC A;  2P4G A;  4PDJ A;  3CSE A;  3ROA A;  3S3V A;  1DR1 A;  3NRR A;  4KEB A;  4RGC A;  3FY8 X;  2D0K A;  4XE6 X;  5HT4 A;  2BL9 A;  2L28 A;  4OR7 A;  2LF1 A;  3JWF A;  1LY4 A;  1RF7 A;  1IA1 A;  3M08 A;  5ECC A;  3F0U X;  3IRM A;  1QZF A;  3QYL A;  4KFJ A;  3RO9 A;  3UM5 A;  4G3M A;  3NU0 A;  1DLS A;  1RE7 A;  2ANQ A;  1DG5 A;  4FGH A;  4XRB A;  4GH8 A;  3SGY A;  3EEK A;  3SAI A;  5HVE A;  3NZB X;  3GI2 A;  5HI6 A;  5HSR A;  4M7U A;  1HFQ A;  3JSU A;  3NXV A;  4I1N A;  2W9T A;  5HF0 X;  1DR4 A;  4LEK X;  2W3B A;  1OHK A;  1DRE A;  3IRN A;  4M7V A;  1JOM A;  3F91 A;  3QLS A;  3IA4 A;  1RA8 A;  5JG0 X;  4KJL A;  1RB3 A;  3KJS A;  4H96 A;  2W3W A;  4M6K A;  3DRC A;  1DRB A;  5ECX A;  3F0X X;  3CL9 A;  1RX4 A;  5CCC A;  3ZPC A;  3JWM A;  1RX9 A;  2W3A A;  1HFP A;  3FQC A;  3SQY X;  4X5J A;  2BLC A;  3FYW X;  5HT5 A;  3JW3 A;  2O7P A;  3F8Y A;  5FDA A;  1ZDR A;  3NZC X;  4X5H A;  2FZH A;  4M6J A;  3NXY A;  4HA7 A;  3FL9 A;  3LG4 A;  3GHW A;  4OSG A;  4M6L A;  4KNE A;  4X5G A;  3SA2 A;  2ANO A;  2GD9 A;  2BLB A;  1TDR A;  4HA9 A;  3QGT A;  3UM8 A;  6DFR A;  2W9G A;  4P66 A;  3JVX A;  4KJJ A;  3JWC A;  4KJK A;  3I8A X;  4XEC X;  4G8Z X;  2H2Q A;  3JWK A;  2DRC A;  3OCH A;  3SA1 A;  4KM2 A;  3RG9 A;  1DIS A;  3F0B X;  2XW7 A;  3EEL A;  5HF2 X;  3DAU A;  3FQZ A;  1IA3 A;  3FQO A;  3DL5 A;  3INV A;  1S3Y A;  4Q6A A;  4G95 A;  1DR7 A;  3DAT A;  5CC9 A;  5HUI A;  4XT7 A;  1PD9 A;  4IXG X;  1DR5 A;  3HBB A;  3NXX A;  1RX8 A;  4X5F A;  3VCO A;  3TQ8 A;  4PSS A;  5DFR A;  1DRH A;  3NXR A;  2KGK A;  4HOE A;  1DAJ A;  1PD8 A;  3TQB A;  3SH2 A;  3Q1H A;  1MVS A;  3DG8 A;  4QLF A;  4ELH A;  1JUV A;  5HQZ A;  3S7A A;  1DG8 A;  5HPB A;  4TU5 X;  4P68 A;  1DR3 A;  1AO8 A;  1DIU A;  1RX1 A;  3N0H A;  3FRA X;  4H97 A;  2B3Z A;  1DDR A; 
#chains in the Genus database with same CATH homology
 3QG2 A;  1S3U A;  1LUD A;  3FL8 A;  2W9S A;  4XT6 A;  3DFR A;  5EAJ A;  3SRU X;  4PTH A;  3FY9 X;  4H98 A;  2BLA A;  1RX7 A;  3QLY A;  4EJ1 A;  4IXF X;  4ELB A;  2HM9 A;  2W3M A;  3FQV A;  1KMV A;  3QFX A;  1DR2 A;  3M09 A;  3NZ9 X;  3FRB X;  3TD8 A;  1DRA A;  3NTZ A;  1HFR A;  1RX3 A;  3DL6 A;  4ELF A;  1CD2 A;  3FRF X;  4LAE X;  4EIG A;  1RA2 A;  4Q0E A;  5U27 A;  1YHO A;  4H95 A;  3FRD X;  3R33 A;  4PTJ A;  2INQ A;  4P3R A;  1RA1 A;  1RH3 A;  4KL9 A;  3KJR A;  3TQA A;  3ZPG A;  1RA9 A;  2C2S A;  4QLE A;  4KM0 A;  1S3V A;  3NXO A;  3JTW A;  4QLG A;  3DGA A;  2G6V A;  3NXT A;  5HSU A;  1AOE A;  3OAF A;  3EIG A;  1VJ3 A;  4HOG A;  3E0B A;  2OIP A;  4NX7 A;  2W3V A;  3F0V X;  3NZD A;  4I13 A;  2D5N A;  4NX6 A;  4Q67 A;  4KYA A;  3IRO A;  3QL0 A;  4KAK A;  3K2H A;  3HJ3 A;  4EIL A;  1CZ3 A;  3KY8 A;  3EEM A;  5DXV A;  3SRW X;  3TQ9 A;  3S9U A;  1DYI A;  2FZJ A;  4KBN A;  4KY4 A;  3L3R A;  1DYR A;  1J3K A;  1DHI A;  4Q0D A;  5JA3 A;  3QLR A;  3IX9 A;  2QK8 A;  5E8Q A;  2ZZA A;  5HQY A;  4PSY A;  2HXV A;  3SRR X;  3QLW A;  3JW5 A;  4DPH A;  1DHF A;  2CIG A;  2C2T A;  1J3I A;  3EX8 A;  1RG7 A;  1M78 A;  2AZN A;  1U72 A;  3SR5 X;  1DYH A;  8DFR A;  1M79 A;  1MVT A;  1U70 A;  4ECK A;  2W9H A;  3F0Q X;  4ELE A;  1DRF A;  3QYO A;  3FQ0 A;  4EIZ A;  3EEJ A;  2ITH A;  1DYJ A;  2OBC A;  3I3R A;  4ELG A;  3GYF A;  1DF7 A;  3FRE X;  3SRQ X;  3QLX A;  3D84 X;  4KLX A;  1VDR A;  3NZA X;  1RB2 A;  3K47 A;  3CLB A;  4M2X A;  4XT4 A;  1RC4 A;  4IXE D;  3F0S X;  3FQF A;  1RD7 A;  3GHV A;  1IA4 A;  4QI9 A;  4QHV A;  3KFY A;  3K45 A;  4DDR A;  4DPD A;  2JYB A;  4P3Q A;  3UM6 A;  1IA2 A;  4DFR A;  1E26 A;  1BOZ A;  3K74 A;  3KGY A;  7DFR A;  1J3J A;  4FHB A;  1RA3 A;  4X5I A;  2FZI A;  4KY8 A;  1JOL A;  1OHJ A;  4KD7 A;  1U71 A;  1RX2 A;  1RX5 A;  3FS6 A;  1PDB A;  1SEJ A;  4XT5 A;  5HVB A;  3GHC A;  4LAH X;  2DHF A;  1DHJ A;  4PST A;  4FGG A;  1DR6 A;  3SRS X;  1D1G A;  1DG7 A;  3FYV X;  4HOF A;  1DDS A;  1AI9 A;  3IA5 A;  5U26 A;  4LAG X;  1M7A A;  1BZF A;  2CD2 A;  4XT8 A;  4QJZ D;  4DP3 A;  1S3W A;  1KLK A;  3QLZ A;  3F8Z A;  1KMS A;  1LY3 A;  3D80 A;  2HQP A;  4CD2 A;  3QL3 A;  3CD2 A;  3NZ6 X;  1RX6 A;  1DLR A;  4QJC A;  2P4G A;  4PDJ A;  3CSE A;  3ROA A;  3S3V A;  1DR1 A;  3NRR A;  4KEB A;  4RGC A;  3FY8 X;  2D0K A;  4XE6 X;  5HT4 A;  2BL9 A;  2L28 A;  4OR7 A;  2LF1 A;  3JWF A;  1LY4 A;  1RF7 A;  1IA1 A;  3M08 A;  5ECC A;  3F0U X;  3IRM A;  1QZF A;  3QYL A;  4KFJ A;  3RO9 A;  3UM5 A;  4G3M A;  3NU0 A;  1DLS A;  1RE7 A;  2ANQ A;  1DG5 A;  4FGH A;  4XRB A;  4GH8 A;  3SGY A;  3EEK A;  3SAI A;  5HVE A;  3NZB X;  3GI2 A;  5HI6 A;  5HSR A;  4M7U A;  1HFQ A;  3JSU A;  3NXV A;  4I1N A;  2W9T A;  5HF0 X;  1DR4 A;  4LEK X;  2W3B A;  1OHK A;  1DRE A;  3IRN A;  4M7V A;  1JOM A;  3F91 A;  3QLS A;  3IA4 A;  1RA8 A;  5JG0 X;  4KJL A;  1RB3 A;  3KJS A;  4H96 A;  2W3W A;  4M6K A;  3DRC A;  1DRB A;  5ECX A;  3F0X X;  3CL9 A;  1RX4 A;  5CCC A;  3ZPC A;  3JWM A;  1RX9 A;  2W3A A;  1HFP A;  3FQC A;  3SQY X;  4X5J A;  2BLC A;  3FYW X;  5HT5 A;  3JW3 A;  2O7P A;  3F8Y A;  5FDA A;  1ZDR A;  3NZC X;  4X5H A;  2FZH A;  4M6J A;  3NXY A;  4HA7 A;  3FL9 A;  3LG4 A;  3GHW A;  4OSG A;  4M6L A;  4KNE A;  4X5G A;  3SA2 A;  2ANO A;  2GD9 A;  2BLB A;  1TDR A;  4HA9 A;  3QGT A;  3UM8 A;  6DFR A;  2W9G A;  4P66 A;  3JVX A;  4KJJ A;  3JWC A;  4KJK A;  3I8A X;  4XEC X;  4G8Z X;  2H2Q A;  3JWK A;  2DRC A;  3OCH A;  3SA1 A;  4KM2 A;  3RG9 A;  1DIS A;  3F0B X;  2XW7 A;  3EEL A;  5HF2 X;  3DAU A;  3FQZ A;  1IA3 A;  3FQO A;  3DL5 A;  3INV A;  1S3Y A;  4Q6A A;  4G95 A;  1DR7 A;  3DAT A;  5CC9 A;  5HUI A;  4XT7 A;  1PD9 A;  4IXG X;  1DR5 A;  3HBB A;  3NXX A;  1RX8 A;  4X5F A;  3VCO A;  3TQ8 A;  4PSS A;  5DFR A;  1DRH A;  3NXR A;  2KGK A;  4HOE A;  1DAJ A;  1PD8 A;  3TQB A;  3SH2 A;  3Q1H A;  1MVS A;  3DG8 A;  4QLF A;  4ELH A;  1JUV A;  5HQZ A;  3S7A A;  1DG8 A;  5HPB A;  4TU5 X;  4P68 A;  1DR3 A;  1AO8 A;  1DIU A;  1RX1 A;  3N0H A;  3FRA X;  4H97 A;  2B3Z A;  1DDR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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