1KAVA

Human tyrosine phosphatase 1b complexed with an inhibitor
Total Genus 106
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
106
sequence length
297
structure length
297
Chain Sequence
EMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHED
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of protein tyrosine phosphatase 1B in complex with inhibitors bearing two phosphotyrosine mimetics.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords PROTEIN-TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1
total genus 106
structure length 297
sequence length 297
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2001-11-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 1kavA00
4WTYA 4AZ1A 1Q6NA 1T4JA 2OZ5A 1C86A 1X24A 2IMGA 2F46A 1WCHA 4ZRTA 3ZMQA 2QBQA 3QCMA 1Q6TA 1QZ0A 4D3RA 1SUGA 1GWZA 3BLUA 4JMJA 3O4UA 5GTJA 2R0BA 3CM3A 2B4OA 1YGRA 2CFVA 2CM8A 2CMBA 3MOWA 3D1QA 4D3QA 3ZM0A 1M3GA 2BZLA 1PA9A 2H4KA 5KADA 1XBOA 2B4SA 1T49A 5AWXA 4GRYA 3A5KA 5KAAA 2F70A 3QCCA 1I9TA 1Q6SA 2HCMA 4DGPA 1XM2A 5KA3A 3EU0A 5IBSA 3GXHA 3D1OA 3U96A 2ZMMA 4RKKA 2RF6A 2SHPA 1ZZWA 1PTUA 2NT2A 2QEPA 1PTTA 1Q6PA 5J8RA 1T48A 1NWEA 4GS0A 3RZ2A 2I6IA 2CMCA 3MOZA 4OHIA 1EEOA 2NV5A 4QUNA 2Y96A 2FH7A 1OEVA 3RO1A 4BJOA 4RI4A 3PS5A 1FPZA 3QCJA 4KYRA 3O5XA 5M43A 1PXHA 3D44A 2F6ZA 2I5XA 4JNBA 1JLNA 3S3HA 3OLRA 3AWFA 5K22A 5EHRA 2A8BA 4JMKA 1WRMA 2J16B 4GWFA 5IBMA 2PQ5A 2BV5A 2I3UA 1Q6MA 3S3KA 1YGUA 3RGOA 1VHRA 1ZC0A 2JJDA 4GE5A 5BX1A 2P4DA 1ZCLA 2C7SA 4R0TA 2CM2A 2B3OA 1OHCA 1BZHA 1PA1A 2HVLA 1C87A 4YAAA 4OHHA 4PVGA 5K23A 2BGEA 4I8NA 2I75A 1XXVA 2VEYA 5KA0A 5KACA 4RI5A 2E0TA 1A5YA 1YWFA 5LXQB 2GJTA 5K25A 1YTNA 3O4SA 2I42A 3QCFA 3EB1A 1YPTA 3ZMPA 3F81A 1NNYA 4OHLA 1D5RA 2NZ6A 2PT0A 1G1HA 4NNDA 2BGDA 5HDEA 1NL9A 1L8GA 2CNFA 3M4UA 4ICZA 1G4WR 3QCKA 5KA7A 4GE6A 3SR9A 4D3PA 4MBBA 3QCNA 2ZN7A 4H34A 3QKQA 2H4GA 1ZCKA 3QCLA 2CM3A 3S4OA 2H4VA 1R6HA 2ESBA 1BZCA 1OETA 4H1OA 2Y2FA 3F99A 3V0HA 5KA9A 5I6VA 2B4UA 2I4HA 3QKPA 3CWEA 5BZXA 1MKPA 1BZJA 3QCGA 3A5JA 1JF7A 1OEOX 1PTVA 3EMUA 3I36A 4JBCA 3V0DA 2PSZA 4GFUA 4KYQA 1PH0A 1YZ4A 4HJPA 2VEVA 4RHGA 1LQFA 4WU3A 3N0AA 1L8KA 2VEXA 3S3FA 5KA1A 3I7ZA 5K24A 4BPCA 4R0SA 1G7GA 2PBNA 1OESA 2VEUA 1PTYA 3QCEA 3D42A 3H2XA 3BLTA 2QBRA 1U25A 3D1HA 1XRIA 2OOQA 1FQ1A 3ZM1A 3F9AA 2Q47A 3V0GA 2CM7A 1C84A 1RPMA 1YN9A 4ZN5A 2FJNA 1NZ7A 1YFOA 1OHDA 4IKCA 1OEUA 3GXGA 2HNPA 4J51A 1YTSA 2PA5A 5BUGA 3ZV2A 4NWFA 4QBEA 3RGQA 4ZI4A 2NTAA 1ONZA 2CNGA 4GFVA 4HRFA 4WU2A 4NX8A 3V0IA 1Q1MA 2CMAA 3SMEA 4WOHA 3B7OA 1GFYA 4KI9A 5BZZA 2QDPA 3S4EA 1C85A 2QDCA 2CNHA 3V0EA 2WGPA 4OHEA 2Q05A 2QCTA 5K9VA 1PYNA 3MMJA 2I3RA 1P15A 4NWGA 2QBSA 1V3AA 2G59A 2NT7A 3OMHA 4NYHA 2AHSA 1NO6A 2I6JA 2HY3A 3BRHA 2QBPA 3O4TA 2B07A 1G1GA 1C83A 1OHEA 5KA4A 1FPRA 1I57A 3LJ8A 2CNEA 2J16A 2I6PA 2PI7A 1OEMX 2F6YA 2H04A 2M3VA 4S0GA 2HXPA 3ZM3A 1I9SA 2QDMA 3BM8A 1G1FA 1U26A 2BIJA 2F6VA 3S3EA 2F6WA 1G7FA 2J17A 4YR8B 3F9BA 2H03A 2AZRA 3I80A 2I4GA 4Y2EA 2CJZA 2I1YA 4Z6BA 1J4XA 1NWLA 1C88A 1YTWA 2HC1A 2F6TA 4OHDA 1AAXA 4ERCA 1KAVA 2VEWA 4QAPA 4HJQA 1LYVA 2HNQA 3V0FA 2GWOA 2F71A 4PYHA 2OC3A 1ECVA 1U24A 2F6FA 5KA8A 2YDUA 1LARA 4GRZA 4TVVA 1EENA 3QCIA 2HB1A 2B4PA 5KABA 3D9CA 1G4US 4QUMA 2H02A 2NLKA 4B04A 2CNIA 5EHPA 4RH9A 2P6XA 2I6OA 5KA2A 1Q6JA 1QXKA 2MBCA 1XXPA 4RDDA 2QCJA 3QCDA 3V0JA 3QCBA 3ZM2A 4Y14A 1KAKA 4QBWA 4R30A 1WAXA 4QAHA 2DXPA 2OUDA 3NMEA 2HC2A 2I6MA 4GE2A 1RXDA 3EAXA 5MMZB 2FJMA 2G6ZA 2A3KA 2B49A 3AWEA 2C46A 3F41A 1ONYA 3O3LA 5K9WA 2I4EA 2GP0A 3AWGA 3EZZA 4RH5A 3QCHA 4DGXA
chains in the Genus database with same CATH superfamily
4WTYA 4AZ1A 1Q6NA 1T4JA 2OZ5A 1C86A 1JBWA 1X24A 2IMGA 2F46A 1WCHA 4ZRTA 3ZMQA 2QBQA 3QCMA 1Q6TA 1QZ0A 4D3RA 1SUGA 1GWZA 3BLUA 4JMJA 2X5OA 3O4UA 4QDIA 5GTJA 2R0BA 3CM3A 2XPCA 2B4OA 1YGRA 2CFVA 2CM8A 2CMBA 3MOWA 3D1QA 4D3QA 3ZM0A 1M3GA 2BZLA 1PA9A 2UUOA 2H4KA 5KADA 1XBOA 2B4SA 1T49A 5AWXA 4GRYA 3A5KA 5KAAA 2F70A 2Y1OA 3QCCA 1I9TA 1Q6SA 2HCMA 4DGPA 1XM2A 5KA3A 3EU0A 5IBSA 3GXHA 3D1OA 3U96A 2ZMMA 4RKKA 2RF6A 2SHPA 1ZZWA 1PTUA 2NT2A 2QEPA 1PTTA 1Q6PA 5J8RA 1T48A 1NWEA 4GS0A 3RZ2A 2I6IA 2Y67A 2CMCA 3MOZA 4OHIA 1EEOA 2NV5A 4QUNA 2Y96A 2FH7A 1OEVA 3RO1A 4BJOA 4RI4A 2VOSA 3PS5A 1FPZA 3QCJA 2Y66A 2UAGA 4KYRA 3O5XA 5M43A 1PXHA 3D44A 2F6ZA 2I5XA 4JNBA 4BUCA 1JLNA 3S3HA 3OLRA 3AWFA 2AM1A 5K22A 5EHRA 3ZM6A 2A8BA 1UAGA 4BUBA 4JMKA 1WRMA 2J16B 4GWFA 5IBMA 2PQ5A 2BV5A 2I3UA 1Q6MA 3S3KA 1YGUA 3RGOA 1VHRA 1ZC0A 2JJDA 4GE5A 5BX1A 2P4DA 2GC5A 1ZCLA 2C7SA 4R0TA 2CM2A 2B3OA 1OHCA 1BZHA 1PA1A 2HVLA 1C87A 4YAAA 4OHHA 4PVGA 5K23A 3ZM5A 1GQQA 2BGEA 4I8NA 2I75A 1EEHA 1XXVA 2VEYA 5KA0A 5KACA 1W7KA 2E0TA 2VTDA 4RI5A 1A5YA 1YWFA 5LXQB 2GJTA 5K25A 3UAGA 1W78A 1YTNA 3O4SA 2I42A 3QCFA 2AM2A 3EB1A 1YPTA 1P3DA 3F81A 1NNYA 4OHLA 3ZMPA 1D5RA 2NZ6A 2PT0A 1G1HA 4NNDA 2BGDA 5HDEA 1NL9A 1L8GA 2CNFA 3M4UA 4ICZA 1G4WR 3QCKA 4UAGA 5KA7A 4GE6A 3SR9A 4D3PA 4MBBA 3QCNA 2ZN7A 4H34A 3QKQA 2H4GA 1ZCKA 3QCLA 5A5FA 2CM3A 3S4OA 1P31A 2H4VA 1R6HA 2ESBA 4CVLA 1BZCA 1OETA 3N2AA 2XJAA 4H1OA 2Y2FA 3F99A 3V0HA 5KA9A 5I6VA 2B4UA 2I4HA 3QKPA 3CWEA 5BZXA 3HN7A 1MKPA 1BZJA 2GCAA 3QCGA 3A5JA 1JF7A 1OEOX 1PTVA 3EMUA 3I36A 4JBCA 3V0DA 2PSZA 1E0DA 4GFUA 4KYQA 1PH0A 1YZ4A 4HJPA 2VEVA 4RHGA 1LQFA 4WU3A 3N0AA 1L8KA 2VEXA 3S3FA 5KA1A 3I7ZA 5K24A 4BPCA 4R0SA 1G7GA 2PBNA 1OESA 2VEUA 1PTYA 3QCEA 3D42A 3H2XA 3BLTA 2QBRA 1U25A 3D1HA 1XRIA 1O5ZA 1FQ1A 2OOQA 3ZM1A 3F9AA 2Q47A 3V0GA 2CM7A 1C84A 3PYZA 1RPMA 1YN9A 4ZN5A 2FJNA 1NZ7A 1YFOA 1OHDA 4IKCA 1OEUA 3GXGA 2HNPA 2UUPA 4J51A 1YTSA 2PA5A 5BUGA 3ZV2A 4NWFA 4QBEA 3RGQA 4ZI4A 2WTZA 2NTAA 1ONZA 2CNGA 4GFVA 4HRFA 4WU2A 4NX8A 3V0IA 1Q1MA 2CMAA 3SMEA 4WOHA 3B7OA 1GFYA 4KI9A 5BZZA 2QDPA 3S4EA 1C85A 2QDCA 2CNHA 3V0EA 2JFGA 2WGPA 4OHEA 2Q05A 2QCTA 5K9VA 3MVNA 1PYNA 3MMJA 2I3RA 1P15A 4NWGA 2QBSA 1V3AA 2G59A 2NT7A 3OMHA 4NYHA 1GQYA 2AHSA 1NO6A 2I6JA 2HY3A 3BRHA 2QBPA 3LK7A 3O4TA 2B07A 1G1GA 1C83A 1OHEA 5KA4A 1FPRA 1I57A 3LJ8A 2CNEA 2J16A 4C12A 2I6PA 1FGSA 2PI7A 1OEMX 2F6YA 2H04A 2M3VA 4S0GA 2HXPA 3ZM3A 1I9SA 2QDMA 3BM8A 1G1FA 4ZIYA 1U26A 2BIJA 2F6VA 3S3EA 2F6WA 1G7FA 2JFFA 2J17A 3ZL8A 4YR8B 3F9BA 5A5EA 2H03A 4CVMA 2AZRA 3I80A 2I4GA 4Y2EA 2WJPA 2GCBA 2CJZA 2I1YA 4C13A 4Z6BA 4CVKA 1J4XA 1NWLA 1C88A 1YTWA 2JFHA 2HC1A 2F6TA 4OHDA 1AAXA 4ERCA 1KAVA 2VEWA 4QAPA 4HJQA 1LYVA 2HNQA 2Y68A 3V0FA 2GWOA 2F71A 3QCZA 4PYHA 2OC3A 1ECVA 1U24A 2F6FA 5KA8A 2YDUA 1LARA 2GC6A 4GRZA 4TVVA 1EENA 3QCIA 2HB1A 2B4PA 5KABA 3D9CA 1G4US 4QUMA 2H02A 2NLKA 4B04A 2CNIA 5EHPA 4RH9A 2P6XA 2VTEA 2I6OA 5KA2A 1J6UA 1Q6JA 1QXKA 2MBCA 1E8CA 1XXPA 4HV4A 4RDDA 2QCJA 3QCDA 3V0JA 3QCBA 2VORA 3ZM2A 4Y14A 1KAKA 4QBWA 4R30A 1WAXA 4QAHA 2F00A 4QF5A 2DXPA 2OUDA 3NMEA 2HC2A 1GG4A 2I6MA 1JBVA 4GE2A 1RXDA 3EAXA 5MMZB 2FJMA 2G6ZA 2A3KA 2B49A 3AWEA 2C46A 3F41A 1ONYA 3O3LA 5K9WA 3NRSA 2I4EA 2GP0A 3AWGA 3EZZA 4RH5A 3QCHA 4DGXA
chains in the Genus database with same CATH topology
4WTYA 4AZ1A 1Q6NA 1T4JA 2OZ5A 1C86A 1X24A 2IMGA 2F46A 1WCHA 4ZRTA 3ZMQA 2QBQA 3QCMA 1Q6TA 1QZ0A 4D3RA 1SUGA 1GWZA 3BLUA 4JMJA 3O4UA 5GTJA 2R0BA 3CM3A 2B4OA 1YGRA 2CFVA 2CM8A 2CMBA 3MOWA 3D1QA 4D3QA 3ZM0A 1M3GA 2BZLA 1PA9A 2H4KA 5KADA 1XBOA 2B4SA 1T49A 5AWXA 4GRYA 3A5KA 5KAAA 2F70A 3QCCA 1I9TA 1Q6SA 2HCMA 4DGPA 1XM2A 5KA3A 3EU0A 5IBSA 3GXHA 3D1OA 3U96A 2ZMMA 4RKKA 2RF6A 2SHPA 1ZZWA 1PTUA 2NT2A 2QEPA 1PTTA 1Q6PA 5J8RA 1T48A 1NWEA 4GS0A 3RZ2A 2I6IA 2CMCA 3MOZA 4OHIA 1EEOA 2NV5A 4QUNA 2Y96A 2FH7A 1OEVA 3RO1A 4BJOA 4RI4A 3PS5A 1FPZA 3QCJA 4KYRA 3O5XA 5M43A 1PXHA 3D44A 2F6ZA 2I5XA 4JNBA 1JLNA 3S3HA 3OLRA 3AWFA 5K22A 5EHRA 2A8BA 4JMKA 1WRMA 2J16B 4GWFA 5IBMA 2PQ5A 2BV5A 2I3UA 1Q6MA 3S3KA 1YGUA 3RGOA 1VHRA 1ZC0A 2JJDA 4GE5A 5BX1A 2P4DA 1ZCLA 2C7SA 4R0TA 2CM2A 2B3OA 1OHCA 1BZHA 1PA1A 2HVLA 1C87A 4YAAA 4OHHA 4PVGA 5K23A 2BGEA 4I8NA 2I75A 1XXVA 2VEYA 5KA0A 5KACA 4RI5A 2E0TA 1A5YA 1YWFA 5LXQB 2GJTA 5K25A 1YTNA 3O4SA 2I42A 3QCFA 3EB1A 1YPTA 3ZMPA 3F81A 1NNYA 4OHLA 1D5RA 2NZ6A 2PT0A 1G1HA 4NNDA 2BGDA 5HDEA 1NL9A 1L8GA 2CNFA 3M4UA 4ICZA 1G4WR 3QCKA 5KA7A 4GE6A 3SR9A 4D3PA 4MBBA 3QCNA 2ZN7A 4H34A 3QKQA 2H4GA 1ZCKA 3QCLA 2CM3A 3S4OA 2H4VA 1R6HA 2ESBA 1BZCA 1OETA 4H1OA 2Y2FA 3F99A 3V0HA 5KA9A 5I6VA 2B4UA 2I4HA 3QKPA 3CWEA 5BZXA 1MKPA 1BZJA 3QCGA 3A5JA 1JF7A 1OEOX 1PTVA 3EMUA 3I36A 4JBCA 3V0DA 2PSZA 4GFUA 4KYQA 1PH0A 1YZ4A 4HJPA 2VEVA 4RHGA 1LQFA 4WU3A 3N0AA 1L8KA 2VEXA 3S3FA 5KA1A 3I7ZA 5K24A 4BPCA 4R0SA 1G7GA 2PBNA 1OESA 2VEUA 1PTYA 3QCEA 3D42A 3H2XA 3BLTA 2QBRA 1U25A 3D1HA 1XRIA 2OOQA 1FQ1A 3ZM1A 3F9AA 2Q47A 3V0GA 2CM7A 1C84A 1RPMA 1YN9A 4ZN5A 2FJNA 1NZ7A 1YFOA 1OHDA 4IKCA 1OEUA 3GXGA 2HNPA 4J51A 1YTSA 2PA5A 5BUGA 3ZV2A 4NWFA 4QBEA 3RGQA 4ZI4A 2NTAA 1ONZA 2CNGA 4GFVA 4HRFA 4WU2A 4NX8A 3V0IA 1Q1MA 2CMAA 3SMEA 4WOHA 3B7OA 1GFYA 4KI9A 5BZZA 2QDPA 3S4EA 1C85A 2QDCA 2CNHA 3V0EA 2WGPA 4OHEA 2Q05A 2QCTA 5K9VA 1PYNA 3MMJA 2I3RA 1P15A 4NWGA 2QBSA 1V3AA 2G59A 2NT7A 3OMHA 4NYHA 2AHSA 1NO6A 2I6JA 2HY3A 3BRHA 2QBPA 3O4TA 2B07A 1G1GA 1C83A 1OHEA 5KA4A 1FPRA 1I57A 3LJ8A 2CNEA 2J16A 2I6PA 2PI7A 1OEMX 2F6YA 2H04A 2M3VA 4S0GA 2HXPA 3ZM3A 1I9SA 2QDMA 3BM8A 1G1FA 1U26A 2BIJA 2F6VA 3S3EA 2F6WA 1G7FA 2J17A 4YR8B 3F9BA 2H03A 2AZRA 3I80A 2I4GA 4Y2EA 2CJZA 2I1YA 4Z6BA 1J4XA 1NWLA 1C88A 1YTWA 2HC1A 2F6TA 4OHDA 1AAXA 4ERCA 1KAVA 2VEWA 4QAPA 4HJQA 1LYVA 2HNQA 3V0FA 2GWOA 2F71A 4PYHA 2OC3A 1ECVA 1U24A 2F6FA 5KA8A 2YDUA 1LARA 4GRZA 4TVVA 1EENA 3QCIA 2HB1A 2B4PA 5KABA 3D9CA 1G4US 4QUMA 2H02A 2NLKA 4B04A 2CNIA 5EHPA 4RH9A 2P6XA 2I6OA 5KA2A 1Q6JA 1QXKA 2MBCA 1XXPA 4RDDA 2QCJA 3QCDA 3V0JA 3QCBA 3ZM2A 4Y14A 1KAKA 4QBWA 4R30A 1WAXA 4QAHA 2DXPA 2OUDA 3NMEA 2HC2A 2I6MA 4GE2A 1RXDA 3EAXA 5MMZB 2FJMA 2G6ZA 2A3KA 2B49A 3AWEA 2C46A 3F41A 1ONYA 3O3LA 5K9WA 2I4EA 2GP0A 3AWGA 3EZZA 4RH5A 3QCHA 4DGXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WTY A;  4AZ1 A;  1Q6N A;  1T4J A;  2OZ5 A;  1C86 A;  1X24 A;  2IMG A;  2F46 A;  1WCH A;  4ZRT A;  3ZMQ A;  2QBQ A;  3QCM A;  1Q6T A;  1QZ0 A;  4D3R A;  1SUG A;  1GWZ A;  3BLU A;  4JMJ A;  3O4U A;  5GTJ A;  2R0B A;  3CM3 A;  2B4O A;  1YGR A;  2CFV A;  2CM8 A;  2CMB A;  3MOW A;  3D1Q A;  4D3Q A;  3ZM0 A;  1M3G A;  2BZL A;  1PA9 A;  2H4K A;  5KAD A;  1XBO A;  2B4S A;  1T49 A;  5AWX A;  4GRY A;  3A5K A;  5KAA A;  2F70 A;  3QCC A;  1I9T A;  1Q6S A;  2HCM A;  4DGP A;  1XM2 A;  5KA3 A;  3EU0 A;  5IBS A;  3GXH A;  3D1O A;  3U96 A;  2ZMM A;  4RKK A;  2RF6 A;  2SHP A;  1ZZW A;  1PTU A;  2NT2 A;  2QEP A;  1PTT A;  1Q6P A;  5J8R A;  1T48 A;  1NWE A;  4GS0 A;  3RZ2 A;  2I6I A;  2CMC A;  3MOZ A;  4OHI A;  1EEO A;  2NV5 A;  4QUN A;  2Y96 A;  2FH7 A;  1OEV A;  3RO1 A;  4BJO A;  4RI4 A;  3PS5 A;  1FPZ A;  3QCJ A;  4KYR A;  3O5X A;  5M43 A;  1PXH A;  3D44 A;  2F6Z A;  2I5X A;  4JNB A;  1JLN A;  3S3H A;  3OLR A;  3AWF A;  5K22 A;  5EHR A;  2A8B A;  4JMK A;  1WRM A;  2J16 B;  4GWF A;  5IBM A;  2PQ5 A;  2BV5 A;  2I3U A;  1Q6M A;  3S3K A;  1YGU A;  3RGO A;  1VHR A;  1ZC0 A;  2JJD A;  4GE5 A;  5BX1 A;  2P4D A;  1ZCL A;  2C7S A;  4R0T A;  2CM2 A;  2B3O A;  1OHC A;  1BZH A;  1PA1 A;  2HVL A;  1C87 A;  4YAA A;  4OHH A;  4PVG A;  5K23 A;  2BGE A;  4I8N A;  2I75 A;  1XXV A;  2VEY A;  5KA0 A;  5KAC A;  4RI5 A;  2E0T A;  1A5Y A;  1YWF A;  5LXQ B;  2GJT A;  5K25 A;  1YTN A;  3O4S A;  2I42 A;  3QCF A;  3EB1 A;  1YPT A;  3ZMP A;  3F81 A;  1NNY A;  4OHL A;  1D5R A;  2NZ6 A;  2PT0 A;  1G1H A;  4NND A;  2BGD A;  5HDE A;  1NL9 A;  1L8G A;  2CNF A;  3M4U A;  4ICZ A;  1G4W R;  3QCK A;  5KA7 A;  4GE6 A;  3SR9 A;  4D3P A;  4MBB A;  3QCN A;  2ZN7 A;  4H34 A;  3QKQ A;  2H4G A;  1ZCK A;  3QCL A;  2CM3 A;  3S4O A;  2H4V A;  1R6H A;  2ESB A;  1BZC A;  1OET A;  4H1O A;  2Y2F A;  3F99 A;  3V0H A;  5KA9 A;  5I6V A;  2B4U A;  2I4H A;  3QKP A;  3CWE A;  5BZX A;  1MKP A;  1BZJ A;  3QCG A;  3A5J A;  1JF7 A;  1OEO X;  1PTV A;  3EMU A;  3I36 A;  4JBC A;  3V0D A;  2PSZ A;  4GFU A;  4KYQ A;  1PH0 A;  1YZ4 A;  4HJP A;  2VEV A;  4RHG A;  1LQF A;  4WU3 A;  3N0A A;  1L8K A;  2VEX A;  3S3F A;  5KA1 A;  3I7Z A;  5K24 A;  4BPC A;  4R0S A;  1G7G A;  2PBN A;  1OES A;  2VEU A;  1PTY A;  3QCE A;  3D42 A;  3H2X A;  3BLT A;  2QBR A;  1U25 A;  3D1H A;  1XRI A;  2OOQ A;  1FQ1 A;  3ZM1 A;  3F9A A;  2Q47 A;  3V0G A;  2CM7 A;  1C84 A;  1RPM A;  1YN9 A;  4ZN5 A;  2FJN A;  1NZ7 A;  1YFO A;  1OHD A;  4IKC A;  1OEU A;  3GXG A;  2HNP A;  4J51 A;  1YTS A;  2PA5 A;  5BUG A;  3ZV2 A;  4NWF A;  4QBE A;  3RGQ A;  4ZI4 A;  2NTA A;  1ONZ A;  2CNG A;  4GFV A;  4HRF A;  4WU2 A;  4NX8 A;  3V0I A;  1Q1M A;  2CMA A;  3SME A;  4WOH A;  3B7O A;  1GFY A;  4KI9 A;  5BZZ A;  2QDP A;  3S4E A;  1C85 A;  2QDC A;  2CNH A;  3V0E A;  2WGP A;  4OHE A;  2Q05 A;  2QCT A;  5K9V A;  1PYN A;  3MMJ A;  2I3R A;  1P15 A;  4NWG A;  2QBS A;  1V3A A;  2G59 A;  2NT7 A;  3OMH A;  4NYH A;  2AHS A;  1NO6 A;  2I6J A;  2HY3 A;  3BRH A;  2QBP A;  3O4T A;  2B07 A;  1G1G A;  1C83 A;  1OHE A;  5KA4 A;  1FPR A;  1I57 A;  3LJ8 A;  2CNE A;  2J16 A;  2I6P A;  2PI7 A;  1OEM X;  2F6Y A;  2H04 A;  2M3V A;  4S0G A;  2HXP A;  3ZM3 A;  1I9S A;  2QDM A;  3BM8 A;  1G1F A;  1U26 A;  2BIJ A;  2F6V A;  3S3E A;  2F6W A;  1G7F A;  2J17 A;  4YR8 B;  3F9B A;  2H03 A;  2AZR A;  3I80 A;  2I4G A;  4Y2E A;  2CJZ A;  2I1Y A;  4Z6B A;  1J4X A;  1NWL A;  1C88 A;  1YTW A;  2HC1 A;  2F6T A;  4OHD A;  1AAX A;  4ERC A;  1KAV A;  2VEW A;  4QAP A;  4HJQ A;  1LYV A;  2HNQ A;  3V0F A;  2GWO A;  2F71 A;  4PYH A;  2OC3 A;  1ECV A;  1U24 A;  2F6F A;  5KA8 A;  2YDU A;  1LAR A;  4GRZ A;  4TVV A;  1EEN A;  3QCI A;  2HB1 A;  2B4P A;  5KAB A;  3D9C A;  1G4U S;  4QUM A;  2H02 A;  2NLK A;  4B04 A;  2CNI A;  5EHP A;  4RH9 A;  2P6X A;  2I6O A;  5KA2 A;  1Q6J A;  1QXK A;  2MBC A;  1XXP A;  4RDD A;  2QCJ A;  3QCD A;  3V0J A;  3QCB A;  3ZM2 A;  4Y14 A;  1KAK A;  4QBW A;  4R30 A;  1WAX A;  4QAH A;  2DXP A;  2OUD A;  3NME A;  2HC2 A;  2I6M A;  4GE2 A;  1RXD A;  3EAX A;  5MMZ B;  2FJM A;  2G6Z A;  2A3K A;  2B49 A;  3AWE A;  2C46 A;  3F41 A;  1ONY A;  3O3L A;  5K9W A;  2I4E A;  2GP0 A;  3AWG A;  3EZZ A;  4RH5 A;  3QCH A;  4DGX A; 
#chains in the Genus database with same CATH topology
 4WTY A;  4AZ1 A;  1Q6N A;  1T4J A;  2OZ5 A;  1C86 A;  1JBW A;  1X24 A;  2IMG A;  2F46 A;  1WCH A;  4ZRT A;  3ZMQ A;  2QBQ A;  3QCM A;  1Q6T A;  1QZ0 A;  4D3R A;  1SUG A;  1GWZ A;  3BLU A;  4JMJ A;  2X5O A;  3O4U A;  4QDI A;  5GTJ A;  2R0B A;  3CM3 A;  2XPC A;  2B4O A;  1YGR A;  2CFV A;  2CM8 A;  2CMB A;  3MOW A;  3D1Q A;  4D3Q A;  3ZM0 A;  1M3G A;  2BZL A;  1PA9 A;  2UUO A;  2H4K A;  5KAD A;  1XBO A;  2B4S A;  1T49 A;  5AWX A;  4GRY A;  3A5K A;  5KAA A;  2F70 A;  2Y1O A;  3QCC A;  1I9T A;  1Q6S A;  2HCM A;  4DGP A;  1XM2 A;  5KA3 A;  3EU0 A;  5IBS A;  3GXH A;  3D1O A;  3U96 A;  2ZMM A;  4RKK A;  2RF6 A;  2SHP A;  1ZZW A;  1PTU A;  2NT2 A;  2QEP A;  1PTT A;  1Q6P A;  5J8R A;  1T48 A;  1NWE A;  4GS0 A;  3RZ2 A;  2I6I A;  2Y67 A;  2CMC A;  3MOZ A;  4OHI A;  1EEO A;  2NV5 A;  4QUN A;  2Y96 A;  2FH7 A;  1OEV A;  3RO1 A;  4BJO A;  4RI4 A;  2VOS A;  3PS5 A;  1FPZ A;  3QCJ A;  2Y66 A;  2UAG A;  4KYR A;  3O5X A;  5M43 A;  1PXH A;  3D44 A;  2F6Z A;  2I5X A;  4JNB A;  4BUC A;  1JLN A;  3S3H A;  3OLR A;  3AWF A;  2AM1 A;  5K22 A;  5EHR A;  3ZM6 A;  2A8B A;  1UAG A;  4BUB A;  4JMK A;  1WRM A;  2J16 B;  4GWF A;  5IBM A;  2PQ5 A;  2BV5 A;  2I3U A;  1Q6M A;  3S3K A;  1YGU A;  3RGO A;  1VHR A;  1ZC0 A;  2JJD A;  4GE5 A;  5BX1 A;  2P4D A;  2GC5 A;  1ZCL A;  2C7S A;  4R0T A;  2CM2 A;  2B3O A;  1OHC A;  1BZH A;  1PA1 A;  2HVL A;  1C87 A;  4YAA A;  4OHH A;  4PVG A;  5K23 A;  3ZM5 A;  1GQQ A;  2BGE A;  4I8N A;  2I75 A;  1EEH A;  1XXV A;  2VEY A;  5KA0 A;  5KAC A;  1W7K A;  2E0T A;  2VTD A;  4RI5 A;  1A5Y A;  1YWF A;  5LXQ B;  2GJT A;  5K25 A;  3UAG A;  1W78 A;  1YTN A;  3O4S A;  2I42 A;  3QCF A;  2AM2 A;  3EB1 A;  1YPT A;  1P3D A;  3F81 A;  1NNY A;  4OHL A;  3ZMP A;  1D5R A;  2NZ6 A;  2PT0 A;  1G1H A;  4NND A;  2BGD A;  5HDE A;  1NL9 A;  1L8G A;  2CNF A;  3M4U A;  4ICZ A;  1G4W R;  3QCK A;  4UAG A;  5KA7 A;  4GE6 A;  3SR9 A;  4D3P A;  4MBB A;  3QCN A;  2ZN7 A;  4H34 A;  3QKQ A;  2H4G A;  1ZCK A;  3QCL A;  5A5F A;  2CM3 A;  3S4O A;  1P31 A;  2H4V A;  1R6H A;  2ESB A;  4CVL A;  1BZC A;  1OET A;  3N2A A;  2XJA A;  4H1O A;  2Y2F A;  3F99 A;  3V0H A;  5KA9 A;  5I6V A;  2B4U A;  2I4H A;  3QKP A;  3CWE A;  5BZX A;  3HN7 A;  1MKP A;  1BZJ A;  2GCA A;  3QCG A;  3A5J A;  1JF7 A;  1OEO X;  1PTV A;  3EMU A;  3I36 A;  4JBC A;  3V0D A;  2PSZ A;  1E0D A;  4GFU A;  4KYQ A;  1PH0 A;  1YZ4 A;  4HJP A;  2VEV A;  4RHG A;  1LQF A;  4WU3 A;  3N0A A;  1L8K A;  2VEX A;  3S3F A;  5KA1 A;  3I7Z A;  5K24 A;  4BPC A;  4R0S A;  1G7G A;  2PBN A;  1OES A;  2VEU A;  1PTY A;  3QCE A;  3D42 A;  3H2X A;  3BLT A;  2QBR A;  1U25 A;  3D1H A;  1XRI A;  1O5Z A;  1FQ1 A;  2OOQ A;  3ZM1 A;  3F9A A;  2Q47 A;  3V0G A;  2CM7 A;  1C84 A;  3PYZ A;  1RPM A;  1YN9 A;  4ZN5 A;  2FJN A;  1NZ7 A;  1YFO A;  1OHD A;  4IKC A;  1OEU A;  3GXG A;  2HNP A;  2UUP A;  4J51 A;  1YTS A;  2PA5 A;  5BUG A;  3ZV2 A;  4NWF A;  4QBE A;  3RGQ A;  4ZI4 A;  2WTZ A;  2NTA A;  1ONZ A;  2CNG A;  4GFV A;  4HRF A;  4WU2 A;  4NX8 A;  3V0I A;  1Q1M A;  2CMA A;  3SME A;  4WOH A;  3B7O A;  1GFY A;  4KI9 A;  5BZZ A;  2QDP A;  3S4E A;  1C85 A;  2QDC A;  2CNH A;  3V0E A;  2JFG A;  2WGP A;  4OHE A;  2Q05 A;  2QCT A;  5K9V A;  3MVN A;  1PYN A;  3MMJ A;  2I3R A;  1P15 A;  4NWG A;  2QBS A;  1V3A A;  2G59 A;  2NT7 A;  3OMH A;  4NYH A;  1GQY A;  2AHS A;  1NO6 A;  2I6J A;  2HY3 A;  3BRH A;  2QBP A;  3LK7 A;  3O4T A;  2B07 A;  1G1G A;  1C83 A;  1OHE A;  5KA4 A;  1FPR A;  1I57 A;  3LJ8 A;  2CNE A;  2J16 A;  4C12 A;  2I6P A;  1FGS A;  2PI7 A;  1OEM X;  2F6Y A;  2H04 A;  2M3V A;  4S0G A;  2HXP A;  3ZM3 A;  1I9S A;  2QDM A;  3BM8 A;  1G1F A;  4ZIY A;  1U26 A;  2BIJ A;  2F6V A;  3S3E A;  2F6W A;  1G7F A;  2JFF A;  2J17 A;  3ZL8 A;  4YR8 B;  3F9B A;  5A5E A;  2H03 A;  4CVM A;  2AZR A;  3I80 A;  2I4G A;  4Y2E A;  2WJP A;  2GCB A;  2CJZ A;  2I1Y A;  4C13 A;  4Z6B A;  4CVK A;  1J4X A;  1NWL A;  1C88 A;  1YTW A;  2JFH A;  2HC1 A;  2F6T A;  4OHD A;  1AAX A;  4ERC A;  1KAV A;  2VEW A;  4QAP A;  4HJQ A;  1LYV A;  2HNQ A;  2Y68 A;  3V0F A;  2GWO A;  2F71 A;  3QCZ A;  4PYH A;  2OC3 A;  1ECV A;  1U24 A;  2F6F A;  5KA8 A;  2YDU A;  1LAR A;  2GC6 A;  4GRZ A;  4TVV A;  1EEN A;  3QCI A;  2HB1 A;  2B4P A;  5KAB A;  3D9C A;  1G4U S;  4QUM A;  2H02 A;  2NLK A;  4B04 A;  2CNI A;  5EHP A;  4RH9 A;  2P6X A;  2VTE A;  2I6O A;  5KA2 A;  1J6U A;  1Q6J A;  1QXK A;  2MBC A;  1E8C A;  1XXP A;  4HV4 A;  4RDD A;  2QCJ A;  3QCD A;  3V0J A;  3QCB A;  2VOR A;  3ZM2 A;  4Y14 A;  1KAK A;  4QBW A;  4R30 A;  1WAX A;  4QAH A;  2F00 A;  4QF5 A;  2DXP A;  2OUD A;  3NME A;  2HC2 A;  1GG4 A;  2I6M A;  1JBV A;  4GE2 A;  1RXD A;  3EAX A;  5MMZ B;  2FJM A;  2G6Z A;  2A3K A;  2B49 A;  3AWE A;  2C46 A;  3F41 A;  1ONY A;  3O3L A;  5K9W A;  3NRS A;  2I4E A;  2GP0 A;  3AWG A;  3EZZ A;  4RH5 A;  3QCH A;  4DGX A; 
#chains in the Genus database with same CATH homology
 4WTY A;  4AZ1 A;  1Q6N A;  1T4J A;  2OZ5 A;  1C86 A;  1X24 A;  2IMG A;  2F46 A;  1WCH A;  4ZRT A;  3ZMQ A;  2QBQ A;  3QCM A;  1Q6T A;  1QZ0 A;  4D3R A;  1SUG A;  1GWZ A;  3BLU A;  4JMJ A;  3O4U A;  5GTJ A;  2R0B A;  3CM3 A;  2B4O A;  1YGR A;  2CFV A;  2CM8 A;  2CMB A;  3MOW A;  3D1Q A;  4D3Q A;  3ZM0 A;  1M3G A;  2BZL A;  1PA9 A;  2H4K A;  5KAD A;  1XBO A;  2B4S A;  1T49 A;  5AWX A;  4GRY A;  3A5K A;  5KAA A;  2F70 A;  3QCC A;  1I9T A;  1Q6S A;  2HCM A;  4DGP A;  1XM2 A;  5KA3 A;  3EU0 A;  5IBS A;  3GXH A;  3D1O A;  3U96 A;  2ZMM A;  4RKK A;  2RF6 A;  2SHP A;  1ZZW A;  1PTU A;  2NT2 A;  2QEP A;  1PTT A;  1Q6P A;  5J8R A;  1T48 A;  1NWE A;  4GS0 A;  3RZ2 A;  2I6I A;  2CMC A;  3MOZ A;  4OHI A;  1EEO A;  2NV5 A;  4QUN A;  2Y96 A;  2FH7 A;  1OEV A;  3RO1 A;  4BJO A;  4RI4 A;  3PS5 A;  1FPZ A;  3QCJ A;  4KYR A;  3O5X A;  5M43 A;  1PXH A;  3D44 A;  2F6Z A;  2I5X A;  4JNB A;  1JLN A;  3S3H A;  3OLR A;  3AWF A;  5K22 A;  5EHR A;  2A8B A;  4JMK A;  1WRM A;  2J16 B;  4GWF A;  5IBM A;  2PQ5 A;  2BV5 A;  2I3U A;  1Q6M A;  3S3K A;  1YGU A;  3RGO A;  1VHR A;  1ZC0 A;  2JJD A;  4GE5 A;  5BX1 A;  2P4D A;  1ZCL A;  2C7S A;  4R0T A;  2CM2 A;  2B3O A;  1OHC A;  1BZH A;  1PA1 A;  2HVL A;  1C87 A;  4YAA A;  4OHH A;  4PVG A;  5K23 A;  2BGE A;  4I8N A;  2I75 A;  1XXV A;  2VEY A;  5KA0 A;  5KAC A;  4RI5 A;  2E0T A;  1A5Y A;  1YWF A;  5LXQ B;  2GJT A;  5K25 A;  1YTN A;  3O4S A;  2I42 A;  3QCF A;  3EB1 A;  1YPT A;  3ZMP A;  3F81 A;  1NNY A;  4OHL A;  1D5R A;  2NZ6 A;  2PT0 A;  1G1H A;  4NND A;  2BGD A;  5HDE A;  1NL9 A;  1L8G A;  2CNF A;  3M4U A;  4ICZ A;  1G4W R;  3QCK A;  5KA7 A;  4GE6 A;  3SR9 A;  4D3P A;  4MBB A;  3QCN A;  2ZN7 A;  4H34 A;  3QKQ A;  2H4G A;  1ZCK A;  3QCL A;  2CM3 A;  3S4O A;  2H4V A;  1R6H A;  2ESB A;  1BZC A;  1OET A;  4H1O A;  2Y2F A;  3F99 A;  3V0H A;  5KA9 A;  5I6V A;  2B4U A;  2I4H A;  3QKP A;  3CWE A;  5BZX A;  1MKP A;  1BZJ A;  3QCG A;  3A5J A;  1JF7 A;  1OEO X;  1PTV A;  3EMU A;  3I36 A;  4JBC A;  3V0D A;  2PSZ A;  4GFU A;  4KYQ A;  1PH0 A;  1YZ4 A;  4HJP A;  2VEV A;  4RHG A;  1LQF A;  4WU3 A;  3N0A A;  1L8K A;  2VEX A;  3S3F A;  5KA1 A;  3I7Z A;  5K24 A;  4BPC A;  4R0S A;  1G7G A;  2PBN A;  1OES A;  2VEU A;  1PTY A;  3QCE A;  3D42 A;  3H2X A;  3BLT A;  2QBR A;  1U25 A;  3D1H A;  1XRI A;  2OOQ A;  1FQ1 A;  3ZM1 A;  3F9A A;  2Q47 A;  3V0G A;  2CM7 A;  1C84 A;  1RPM A;  1YN9 A;  4ZN5 A;  2FJN A;  1NZ7 A;  1YFO A;  1OHD A;  4IKC A;  1OEU A;  3GXG A;  2HNP A;  4J51 A;  1YTS A;  2PA5 A;  5BUG A;  3ZV2 A;  4NWF A;  4QBE A;  3RGQ A;  4ZI4 A;  2NTA A;  1ONZ A;  2CNG A;  4GFV A;  4HRF A;  4WU2 A;  4NX8 A;  3V0I A;  1Q1M A;  2CMA A;  3SME A;  4WOH A;  3B7O A;  1GFY A;  4KI9 A;  5BZZ A;  2QDP A;  3S4E A;  1C85 A;  2QDC A;  2CNH A;  3V0E A;  2WGP A;  4OHE A;  2Q05 A;  2QCT A;  5K9V A;  1PYN A;  3MMJ A;  2I3R A;  1P15 A;  4NWG A;  2QBS A;  1V3A A;  2G59 A;  2NT7 A;  3OMH A;  4NYH A;  2AHS A;  1NO6 A;  2I6J A;  2HY3 A;  3BRH A;  2QBP A;  3O4T A;  2B07 A;  1G1G A;  1C83 A;  1OHE A;  5KA4 A;  1FPR A;  1I57 A;  3LJ8 A;  2CNE A;  2J16 A;  2I6P A;  2PI7 A;  1OEM X;  2F6Y A;  2H04 A;  2M3V A;  4S0G A;  2HXP A;  3ZM3 A;  1I9S A;  2QDM A;  3BM8 A;  1G1F A;  1U26 A;  2BIJ A;  2F6V A;  3S3E A;  2F6W A;  1G7F A;  2J17 A;  4YR8 B;  3F9B A;  2H03 A;  2AZR A;  3I80 A;  2I4G A;  4Y2E A;  2CJZ A;  2I1Y A;  4Z6B A;  1J4X A;  1NWL A;  1C88 A;  1YTW A;  2HC1 A;  2F6T A;  4OHD A;  1AAX A;  4ERC A;  1KAV A;  2VEW A;  4QAP A;  4HJQ A;  1LYV A;  2HNQ A;  3V0F A;  2GWO A;  2F71 A;  4PYH A;  2OC3 A;  1ECV A;  1U24 A;  2F6F A;  5KA8 A;  2YDU A;  1LAR A;  4GRZ A;  4TVV A;  1EEN A;  3QCI A;  2HB1 A;  2B4P A;  5KAB A;  3D9C A;  1G4U S;  4QUM A;  2H02 A;  2NLK A;  4B04 A;  2CNI A;  5EHP A;  4RH9 A;  2P6X A;  2I6O A;  5KA2 A;  1Q6J A;  1QXK A;  2MBC A;  1XXP A;  4RDD A;  2QCJ A;  3QCD A;  3V0J A;  3QCB A;  3ZM2 A;  4Y14 A;  1KAK A;  4QBW A;  4R30 A;  1WAX A;  4QAH A;  2DXP A;  2OUD A;  3NME A;  2HC2 A;  2I6M A;  4GE2 A;  1RXD A;  3EAX A;  5MMZ B;  2FJM A;  2G6Z A;  2A3K A;  2B49 A;  3AWE A;  2C46 A;  3F41 A;  1ONY A;  3O3L A;  5K9W A;  2I4E A;  2GP0 A;  3AWG A;  3EZZ A;  4RH5 A;  3QCH A;  4DGX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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