1KEAA

Structure of a thermostable thymine-dna glycosylase
Total Genus 78
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
78
sequence length
217
structure length
217
Chain Sequence
DATNKKRKVFVSTILTFWNTDRRDFPWRHTRDPYVILITEILLRRTTAGHVKKIYDKFFVKYKCFEDILKTPKSEIAKDIKEIGLSNQRAEQLKELARVVINDYGGRVPRNRKAILDLPGVGKYTCAAVMCLAFGKKAAMVDANFVRVINRYFGGSYENLNYNHKALWELAETLVPGGKCRDFNLGLMDFSAIICAPRKPKCEKCGMSKLCSYYEKC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and activity of a thermostable thymine-DNA glycosylase: evidence for base twisting to remove mismatched normal DNA bases.
pubmed doi rcsb
molecule tags Hydrolase
source organism Methanothermobacter thermautotrophicus
molecule keywords Possible G-T mismatches repair enzyme
total genus 78
structure length 217
sequence length 217
ec nomenclature ec 3.2.2.-:
pdb deposition date 2001-11-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1keaA02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1keaA01
3OGDA 4OFAA 1LWVA 4AI5A 2YG8A 3I0WA 4B23A 4YOQA 2YG9A 1LMZA 1FN7A 2XHIA 3S6IA 2JHNA 1WEFA 4OFEA 1XQOA 4OFHA 1M3HA 2JHJA 4YPRA 3IHOA 5AN4A 2NOIA 3CVSA 3OH6A 4UNFA 4B24A 1PU6A 4PIIA 4EW4A 1KG4A 1N39A 4E9EA 1DIZA 1MUNA 2I5WA 5KN8A 3CWSA 1WEGA 1N3AA 2NOHA 1LWYA 3FHFA 4B22A 4B21A 1XQPA 3IH7A 1MPGA 4EW0A 3CVTA 2OFKA 3F0ZA 3FSPA 2NOEA 1RRQA 3KNTA 1ORNA 1HU0A 1PU8A 1YQRA 1XG7A 4EA5A 1M3QA 1KQJA 1P7MA 3G0QA 1LWWA 3I0XA 1MUDA 3KTUA 4E9GA 4EJZA 3OH9A 4AIAA 3CWUA 2NOFA 1ORPA 1KG2A 4HSBA 4DK9A 1YQLA 3FHGA 1EBMA 3CWAA 4EVVA 1YQKA 1KG5A 3F10A 4EJYA 1KG6A 4E9HA 3CW7A 5KN9A 1PU7A 3N0UA 1WEIA 5DPKA 3D4VA 1MUYA 1KO9A 1KG7A 3N5NX 2NOZA 4AI4A 2ABKA 1P59A 2OFIA 1RRSA 2H56A 5CHZA 1KG3A 4YPHA 4UOBA 4E9FA 1NGNA 2NOBA 3CWTA 2NOLA 1VRLA 1PVSA 4EA4A 1N3CA 1NKUA 1KEAA 1YQMA 2JG6A
chains in the Genus database with same CATH superfamily
3OGDA 4OFAA 3OY9A 1LWVA 4AI5A 4E7KA 2YG8A 3I0WA 4B23A 4YOQA 4BACA 3S3MA 4ZTFA 2YG9A 1LMZA 3L2QA 1FN7A 2XHIA 3S6IA 3OYBA 2JHNA 1WEFA 4OFEA 3OYKA 3OYFA 1XQOA 4OFHA 3NNQA 1M3HA 2JHJA 4YPRA 4E7HA 3IHOA 5AN4A 3VW4A 2NOIA 3CVSA 4IKFA 3OYNA 3OH6A 4UNFA 4B24A 3L2UA 1PU6A 4PIIA 4EW4A 1KG4A 1N39A 4E7IA 4E9EA 1DIZA 3OYDA 3L2WA 1MUNA 2I5WA 5KN8A 4BE2A 4BDYA 3CWSA 3OYMA 1WEGA 1N3AA 2NOHA 1LWYA 3FHFA 4E7JA 4B22A 4B21A 1XQPA 3IH7A 1MPGA 3OYAA 4EW0A 3OS0A 3LCNA 3CVTA 2OFKA 3L2RA 2W04A 3F0ZA 3FSPA 2NOEA 1RRQA 3KNTA 1ORNA 1HU0A 1PU8A 4BDZA 1YQRA 1XG7A 4EA5A 1M3QA 1KQJA 1P7MA 3G0QA 1LWWA 3I0XA 5FROA 3OYCA 1MUDA 3KTUA 4E9GA 4EJZA 3OH9A 4AIAA 4BE1A 3CWUA 2NOFA 1ORPA 1KG2A 4HSBA 4BE0A 4DK9A 3L2VA 3FHGA 3OYJA 1YQLA 3CWAA 4EVVA 1YQKA 1EBMA 1KG5A 3F10A 3OS1A 4EJYA 1KG6A 2W03A 4E9HA 1U84A 3CW7A 3OS2A 5KN9A 1PU7A 3N0UA 1WEIA 3OYLA 5DPKA 3D4VA 1MUYA 2JPSA 3S3NA 1KO9A 4ZTJA 1KG7A 3N5NX 3OYGA 3OYIA 3R2XC 3OYHA 3S3OA 5FRNA 2NOZA 4AI4A 2ABKA 1P59A 2OFIA 4NZGA 4E7LA 1RRSA 2H56A 5CHZA 1KG3A 4YPHA 4UOBA 4E9FA 1NGNA 2V75A 3OYEA 2NOBA 3CWTA 2NOLA 1VRLA 1PVSA 4EA4A 1N3CA 1NKUA 5FRMA 1KEAA 1YQMA 2JG6A
chains in the Genus database with same CATH topology
3OGDA 4OFAA 1LWVA 4AI5A 2YG8A 3I0WA 4B23A 4YOQA 2YG9A 1LMZA 1FN7A 2XHIA 3S6IA 2JHNA 1WEFA 4OFEA 1XQOA 4OFHA 1M3HA 2JHJA 4YPRA 3IHOA 5AN4A 2NOIA 3CVSA 3OH6A 4UNFA 4B24A 1PU6A 4PIIA 4EW4A 1KG4A 1N39A 4E9EA 1DIZA 1MUNA 2I5WA 5KN8A 3CWSA 1WEGA 1N3AA 2NOHA 1LWYA 3FHFA 4B22A 4B21A 1XQPA 3IH7A 1MPGA 4EW0A 3CVTA 2OFKA 3F0ZA 3FSPA 2NOEA 1RRQA 3KNTA 1ORNA 1HU0A 1PU8A 1YQRA 1XG7A 4EA5A 1M3QA 1KQJA 1P7MA 3G0QA 1LWWA 3I0XA 1MUDA 3KTUA 4E9GA 4EJZA 3OH9A 4AIAA 3CWUA 2NOFA 1ORPA 1KG2A 4HSBA 4DK9A 1YQLA 3FHGA 1EBMA 3CWAA 4EVVA 1YQKA 1KG5A 3F10A 4EJYA 1KG6A 4E9HA 3CW7A 5KN9A 1PU7A 3N0UA 1WEIA 5DPKA 3D4VA 1MUYA 1KO9A 1KG7A 3N5NX 2NOZA 4AI4A 2ABKA 1P59A 2OFIA 1RRSA 2H56A 5CHZA 1KG3A 4YPHA 4UOBA 4E9FA 1NGNA 2NOBA 3CWTA 2NOLA 1VRLA 1PVSA 4EA4A 1N3CA 1NKUA 1KEAA 1YQMA 2JG6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OGD A;  4OFA A;  1LWV A;  4AI5 A;  2YG8 A;  3I0W A;  4B23 A;  4YOQ A;  2YG9 A;  1LMZ A;  1FN7 A;  2XHI A;  3S6I A;  2JHN A;  1WEF A;  4OFE A;  1XQO A;  4OFH A;  1M3H A;  2JHJ A;  4YPR A;  3IHO A;  5AN4 A;  2NOI A;  3CVS A;  3OH6 A;  4UNF A;  4B24 A;  1PU6 A;  4PII A;  4EW4 A;  1KG4 A;  1N39 A;  4E9E A;  1DIZ A;  1MUN A;  2I5W A;  5KN8 A;  3CWS A;  1WEG A;  1N3A A;  2NOH A;  1LWY A;  3FHF A;  4B22 A;  4B21 A;  1XQP A;  3IH7 A;  1MPG A;  4EW0 A;  3CVT A;  2OFK A;  3F0Z A;  3FSP A;  2NOE A;  1RRQ A;  3KNT A;  1ORN A;  1HU0 A;  1PU8 A;  1YQR A;  1XG7 A;  4EA5 A;  1M3Q A;  1KQJ A;  1P7M A;  3G0Q A;  1LWW A;  3I0X A;  1MUD A;  3KTU A;  4E9G A;  4EJZ A;  3OH9 A;  4AIA A;  3CWU A;  2NOF A;  1ORP A;  1KG2 A;  4HSB A;  4DK9 A;  1YQL A;  3FHG A;  1EBM A;  3CWA A;  4EVV A;  1YQK A;  1KG5 A;  3F10 A;  4EJY A;  1KG6 A;  4E9H A;  3CW7 A;  5KN9 A;  1PU7 A;  3N0U A;  1WEI A;  5DPK A;  3D4V A;  1MUY A;  1KO9 A;  1KG7 A;  3N5N X;  2NOZ A;  4AI4 A;  2ABK A;  1P59 A;  2OFI A;  1RRS A;  2H56 A;  5CHZ A;  1KG3 A;  4YPH A;  4UOB A;  4E9F A;  1NGN A;  2NOB A;  3CWT A;  2NOL A;  1VRL A;  1PVS A;  4EA4 A;  1N3C A;  1NKU A;  1KEA A;  1YQM A;  2JG6 A; 
#chains in the Genus database with same CATH topology
 3OGD A;  4OFA A;  3OY9 A;  1LWV A;  4AI5 A;  4E7K A;  2YG8 A;  3I0W A;  4B23 A;  4YOQ A;  4BAC A;  3S3M A;  4ZTF A;  2YG9 A;  1LMZ A;  3L2Q A;  1FN7 A;  2XHI A;  3S6I A;  3OYB A;  2JHN A;  1WEF A;  4OFE A;  3OYK A;  3OYF A;  1XQO A;  4OFH A;  3NNQ A;  1M3H A;  2JHJ A;  4YPR A;  4E7H A;  3IHO A;  5AN4 A;  3VW4 A;  2NOI A;  3CVS A;  4IKF A;  3OYN A;  3OH6 A;  4UNF A;  4B24 A;  3L2U A;  1PU6 A;  4PII A;  4EW4 A;  1KG4 A;  1N39 A;  4E7I A;  4E9E A;  1DIZ A;  3OYD A;  3L2W A;  1MUN A;  2I5W A;  5KN8 A;  4BE2 A;  4BDY A;  3CWS A;  3OYM A;  1WEG A;  1N3A A;  2NOH A;  1LWY A;  3FHF A;  4E7J A;  4B22 A;  4B21 A;  1XQP A;  3IH7 A;  1MPG A;  3OYA A;  4EW0 A;  3OS0 A;  3LCN A;  3CVT A;  2OFK A;  3L2R A;  2W04 A;  3F0Z A;  3FSP A;  2NOE A;  1RRQ A;  3KNT A;  1ORN A;  1HU0 A;  1PU8 A;  4BDZ A;  1YQR A;  1XG7 A;  4EA5 A;  1M3Q A;  1KQJ A;  1P7M A;  3G0Q A;  1LWW A;  3I0X A;  5FRO A;  3OYC A;  1MUD A;  3KTU A;  4E9G A;  4EJZ A;  3OH9 A;  4AIA A;  4BE1 A;  3CWU A;  2NOF A;  1ORP A;  1KG2 A;  4HSB A;  4BE0 A;  4DK9 A;  3L2V A;  3FHG A;  3OYJ A;  1YQL A;  3CWA A;  4EVV A;  1YQK A;  1EBM A;  1KG5 A;  3F10 A;  3OS1 A;  4EJY A;  1KG6 A;  2W03 A;  4E9H A;  1U84 A;  3CW7 A;  3OS2 A;  5KN9 A;  1PU7 A;  3N0U A;  1WEI A;  3OYL A;  5DPK A;  3D4V A;  1MUY A;  2JPS A;  3S3N A;  1KO9 A;  4ZTJ A;  1KG7 A;  3N5N X;  3OYG A;  3OYI A;  3R2X C;  3OYH A;  3S3O A;  5FRN A;  2NOZ A;  4AI4 A;  2ABK A;  1P59 A;  2OFI A;  4NZG A;  4E7L A;  1RRS A;  2H56 A;  5CHZ A;  1KG3 A;  4YPH A;  4UOB A;  4E9F A;  1NGN A;  2V75 A;  3OYE A;  2NOB A;  3CWT A;  2NOL A;  1VRL A;  1PVS A;  4EA4 A;  1N3C A;  1NKU A;  5FRM A;  1KEA A;  1YQM A;  2JG6 A; 
#chains in the Genus database with same CATH homology
 3OGD A;  4OFA A;  1LWV A;  4AI5 A;  2YG8 A;  3I0W A;  4B23 A;  4YOQ A;  2YG9 A;  1LMZ A;  1FN7 A;  2XHI A;  3S6I A;  2JHN A;  1WEF A;  4OFE A;  1XQO A;  4OFH A;  1M3H A;  2JHJ A;  4YPR A;  3IHO A;  5AN4 A;  2NOI A;  3CVS A;  3OH6 A;  4UNF A;  4B24 A;  1PU6 A;  4PII A;  4EW4 A;  1KG4 A;  1N39 A;  4E9E A;  1DIZ A;  1MUN A;  2I5W A;  5KN8 A;  3CWS A;  1WEG A;  1N3A A;  2NOH A;  1LWY A;  3FHF A;  4B22 A;  4B21 A;  1XQP A;  3IH7 A;  1MPG A;  4EW0 A;  3CVT A;  2OFK A;  3F0Z A;  3FSP A;  2NOE A;  1RRQ A;  3KNT A;  1ORN A;  1HU0 A;  1PU8 A;  1YQR A;  1XG7 A;  4EA5 A;  1M3Q A;  1KQJ A;  1P7M A;  3G0Q A;  1LWW A;  3I0X A;  1MUD A;  3KTU A;  4E9G A;  4EJZ A;  3OH9 A;  4AIA A;  3CWU A;  2NOF A;  1ORP A;  1KG2 A;  4HSB A;  4DK9 A;  1YQL A;  3FHG A;  1EBM A;  3CWA A;  4EVV A;  1YQK A;  1KG5 A;  3F10 A;  4EJY A;  1KG6 A;  4E9H A;  3CW7 A;  5KN9 A;  1PU7 A;  3N0U A;  1WEI A;  5DPK A;  3D4V A;  1MUY A;  1KO9 A;  1KG7 A;  3N5N X;  2NOZ A;  4AI4 A;  2ABK A;  1P59 A;  2OFI A;  1RRS A;  2H56 A;  5CHZ A;  1KG3 A;  4YPH A;  4UOB A;  4E9F A;  1NGN A;  2NOB A;  3CWT A;  2NOL A;  1VRL A;  1PVS A;  4EA4 A;  1N3C A;  1NKU A;  1KEA A;  1YQM A;  2JG6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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