1KG2A

Crystal structure of the core fragment of muty from e.coli at 1.2a resolution
Total Genus 77
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
sequence length
224
structure length
224
Chain Sequence
MQASQFSAQVLDWYDKYGRKTLPWQIDKTPYKVWLSEVMLQQTQVATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGGKFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILDGNVKRVLARCYAVSGWPGKKEVENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSKPKCSLCPLQNGCIAAANNSWALYPGKKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords A/G-specific adenine glycosylase
publication title Analysis of the E.coli MutY DNA glycosylase structure and function by site-directed mutagenesis
rcsb
source organism Escherichia coli
molecule tags Hydrolase
total genus 77
structure length 224
sequence length 224
ec nomenclature ec 3.2.2.31: Adenine glycosylase.
pdb deposition date 2001-11-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00633 HHH Helix-hairpin-helix motif
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
A PF10576 EndIII_4Fe-2S Iron-sulfur binding domain of endonuclease III
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1kg2A02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1kg2A01
3D4VA 4UNFA 5KN8A 1WEIA 1LMZA 3F0ZA 1RRQA 3I0WA 2I5WA 3CWSA 1YQRA 2OFIA 1LWWA 3FSPA 4E9HA 4OFHA 1P7MA 3F10A 1N3AA 4E9FA 1MUNA 2JHJA 3IHOA 1YQMA 1KG4A 4EVVA 3CWAA 3IH7A 4HSBA 1N3CA 3CW7A 1XQOA 3FHGA 3CVSA 4EJZA 1XG7A 3N5NX 2YG8A 1RRSA 2XHIA 5AN4A 4EW0A 1KEAA 3N0UA 3KTUA 3CVTA 4PIIA 1MUYA 1NKUA 2YG9A 1NGNA 2JHNA 1LWYA 1LWVA 3OH6A 4B23A 5KN9A 1KG3A 5CHZA 1KG2A 1YQKA 4EJYA 1PU7A 4OFEA 1KO9A 1VRLA 2NOLA 3G0QA 4AIAA 4AI5A 1DIZA 4EW4A 1YQLA 3CWUA 1FN7A 1MPGA 1XQPA 3I0XA 2OFKA 2NOZA 1PU8A 4E9GA 3FHFA 2ABKA 1M3HA 1KG5A 4B24A 1WEGA 4B22A 1ORPA 4YPHA 4OFAA 1MUDA 2JG6A 1WEFA 4YOQA 1KG6A 3S6IA 3KNTA 4B21A 2NOIA 1KQJA 3CWTA 2NOHA 1M3QA 4E9EA 2NOEA 4UOBA 1KG7A 4EA5A 3OH9A 1PU6A 2NOBA 2NOFA 4YPRA 1N39A 4EA4A 3OGDA 1P59A 1ORNA 1EBMA 4DK9A 4AI4A 1HU0A 2H56A 5DPKA 1PVSA
chains in the Genus database with same CATH superfamily
3D4VA 4UNFA 5KN8A 1WEIA 1LMZA 3F0ZA 1RRQA 3I0WA 2I5WA 3OYBA 3CWSA 1YQRA 3OS1A 4BE2A 2OFIA 3OYLA 1LWWA 3FSPA 4E9HA 4OFHA 1P7MA 4BDYA 3F10A 4E7IA 3OYIA 1N3AA 4E9FA 5FRNA 3LCNA 1MUNA 2JHJA 3IHOA 1YQMA 1KG4A 3S3MA 4E7HA 4EVVA 3R2XC 3CWAA 3IH7A 4HSBA 4E7JA 1N3CA 3CW7A 1XQOA 3FHGA 3CVSA 4IKFA 4EJZA 1XG7A 3N5NX 3S3NA 2YG8A 3L2RA 1RRSA 2XHIA 4NZGA 4ZTJA 5AN4A 4EW0A 1U84A 3L2UA 1KEAA 3OYGA 4ZTFA 3N0UA 3KTUA 3CVTA 4PIIA 4E7LA 1MUYA 1NKUA 2YG9A 1NGNA 2JHNA 1LWYA 3S3OA 3OH6A 1LWVA 2V75A 4B23A 5KN9A 1KG3A 5CHZA 1KG2A 3OYDA 1YQKA 2W03A 4EJYA 1PU7A 4OFEA 3L2VA 1KO9A 3L2WA 1VRLA 2NOLA 4E7KA 3G0QA 4AIAA 5FRMA 4AI5A 3OS0A 1DIZA 4EW4A 1YQLA 4BE1A 2W04A 3CWUA 1FN7A 3NNQA 1MPGA 3VW4A 2JPSA 1XQPA 3I0XA 2OFKA 2NOZA 1PU8A 4E9GA 3OYHA 3FHFA 3OS2A 3OYMA 2ABKA 3OYNA 1M3HA 1KG5A 3L2QA 3OYJA 4B24A 1WEGA 4B22A 3OYFA 3OYAA 4YPHA 4OFAA 1ORPA 1MUDA 2JG6A 1WEFA 4YOQA 1KG6A 3S6IA 3KNTA 4B21A 2NOIA 1KQJA 3CWTA 2NOHA 3OYEA 1M3QA 4E9EA 2NOEA 4UOBA 1KG7A 5FROA 4BACA 4EA5A 3OYCA 3OH9A 1PU6A 2NOBA 2NOFA 3OY9A 4YPRA 1N39A 4EA4A 3OGDA 1P59A 1ORNA 4BDZA 1EBMA 4DK9A 3OYKA 4BE0A 4AI4A 1HU0A 2H56A 5DPKA 1PVSA
chains in the Genus database with same CATH topology
3D4VA 4UNFA 5KN8A 1WEIA 1LMZA 3F0ZA 1RRQA 3I0WA 2I5WA 3CWSA 1YQRA 2OFIA 1LWWA 3FSPA 4E9HA 4OFHA 1P7MA 3F10A 1N3AA 4E9FA 1MUNA 2JHJA 3IHOA 1YQMA 1KG4A 4EVVA 3CWAA 3IH7A 4HSBA 1N3CA 3CW7A 1XQOA 3FHGA 3CVSA 4EJZA 1XG7A 3N5NX 2YG8A 1RRSA 2XHIA 5AN4A 4EW0A 1KEAA 3N0UA 3KTUA 3CVTA 4PIIA 1MUYA 1NKUA 2YG9A 1NGNA 2JHNA 1LWYA 1LWVA 3OH6A 4B23A 5KN9A 1KG3A 5CHZA 1KG2A 1YQKA 4EJYA 1PU7A 4OFEA 1KO9A 1VRLA 2NOLA 3G0QA 4AIAA 4AI5A 1DIZA 4EW4A 1YQLA 3CWUA 1FN7A 1MPGA 1XQPA 3I0XA 2OFKA 2NOZA 1PU8A 4E9GA 3FHFA 2ABKA 1M3HA 1KG5A 4B24A 1WEGA 4B22A 1ORPA 4YPHA 4OFAA 1MUDA 2JG6A 1WEFA 4YOQA 1KG6A 3S6IA 3KNTA 4B21A 2NOIA 1KQJA 3CWTA 2NOHA 1M3QA 4E9EA 2NOEA 4UOBA 1KG7A 4EA5A 3OH9A 1PU6A 2NOBA 2NOFA 4YPRA 1N39A 4EA4A 3OGDA 1P59A 1ORNA 1EBMA 4DK9A 4AI4A 1HU0A 2H56A 5DPKA 1PVSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3D4V A;  4UNF A;  5KN8 A;  1WEI A;  1LMZ A;  3F0Z A;  1RRQ A;  3I0W A;  2I5W A;  3CWS A;  1YQR A;  2OFI A;  1LWW A;  3FSP A;  4E9H A;  4OFH A;  1P7M A;  3F10 A;  1N3A A;  4E9F A;  1MUN A;  2JHJ A;  3IHO A;  1YQM A;  1KG4 A;  4EVV A;  3CWA A;  3IH7 A;  4HSB A;  1N3C A;  3CW7 A;  1XQO A;  3FHG A;  3CVS A;  4EJZ A;  1XG7 A;  3N5N X;  2YG8 A;  1RRS A;  2XHI A;  5AN4 A;  4EW0 A;  1KEA A;  3N0U A;  3KTU A;  3CVT A;  4PII A;  1MUY A;  1NKU A;  2YG9 A;  1NGN A;  2JHN A;  1LWY A;  1LWV A;  3OH6 A;  4B23 A;  5KN9 A;  1KG3 A;  5CHZ A;  1KG2 A;  1YQK A;  4EJY A;  1PU7 A;  4OFE A;  1KO9 A;  1VRL A;  2NOL A;  3G0Q A;  4AIA A;  4AI5 A;  1DIZ A;  4EW4 A;  1YQL A;  3CWU A;  1FN7 A;  1MPG A;  1XQP A;  3I0X A;  2OFK A;  2NOZ A;  1PU8 A;  4E9G A;  3FHF A;  2ABK A;  1M3H A;  1KG5 A;  4B24 A;  1WEG A;  4B22 A;  1ORP A;  4YPH A;  4OFA A;  1MUD A;  2JG6 A;  1WEF A;  4YOQ A;  1KG6 A;  3S6I A;  3KNT A;  4B21 A;  2NOI A;  1KQJ A;  3CWT A;  2NOH A;  1M3Q A;  4E9E A;  2NOE A;  4UOB A;  1KG7 A;  4EA5 A;  3OH9 A;  1PU6 A;  2NOB A;  2NOF A;  4YPR A;  1N39 A;  4EA4 A;  3OGD A;  1P59 A;  1ORN A;  1EBM A;  4DK9 A;  4AI4 A;  1HU0 A;  2H56 A;  5DPK A;  1PVS A; 
#chains in the Genus database with same CATH topology
 3D4V A;  4UNF A;  5KN8 A;  1WEI A;  1LMZ A;  3F0Z A;  1RRQ A;  3I0W A;  2I5W A;  3OYB A;  3CWS A;  1YQR A;  3OS1 A;  4BE2 A;  2OFI A;  3OYL A;  1LWW A;  3FSP A;  4E9H A;  4OFH A;  1P7M A;  4BDY A;  3F10 A;  4E7I A;  3OYI A;  1N3A A;  4E9F A;  5FRN A;  3LCN A;  1MUN A;  2JHJ A;  3IHO A;  1YQM A;  1KG4 A;  3S3M A;  4E7H A;  4EVV A;  3R2X C;  3CWA A;  3IH7 A;  4HSB A;  4E7J A;  1N3C A;  3CW7 A;  1XQO A;  3FHG A;  3CVS A;  4IKF A;  4EJZ A;  1XG7 A;  3N5N X;  3S3N A;  2YG8 A;  3L2R A;  1RRS A;  2XHI A;  4NZG A;  4ZTJ A;  5AN4 A;  4EW0 A;  1U84 A;  3L2U A;  1KEA A;  3OYG A;  4ZTF A;  3N0U A;  3KTU A;  3CVT A;  4PII A;  4E7L A;  1MUY A;  1NKU A;  2YG9 A;  1NGN A;  2JHN A;  1LWY A;  3S3O A;  3OH6 A;  1LWV A;  2V75 A;  4B23 A;  5KN9 A;  1KG3 A;  5CHZ A;  1KG2 A;  3OYD A;  1YQK A;  2W03 A;  4EJY A;  1PU7 A;  4OFE A;  3L2V A;  1KO9 A;  3L2W A;  1VRL A;  2NOL A;  4E7K A;  3G0Q A;  4AIA A;  5FRM A;  4AI5 A;  3OS0 A;  1DIZ A;  4EW4 A;  1YQL A;  4BE1 A;  2W04 A;  3CWU A;  1FN7 A;  3NNQ A;  1MPG A;  3VW4 A;  2JPS A;  1XQP A;  3I0X A;  2OFK A;  2NOZ A;  1PU8 A;  4E9G A;  3OYH A;  3FHF A;  3OS2 A;  3OYM A;  2ABK A;  3OYN A;  1M3H A;  1KG5 A;  3L2Q A;  3OYJ A;  4B24 A;  1WEG A;  4B22 A;  3OYF A;  3OYA A;  4YPH A;  4OFA A;  1ORP A;  1MUD A;  2JG6 A;  1WEF A;  4YOQ A;  1KG6 A;  3S6I A;  3KNT A;  4B21 A;  2NOI A;  1KQJ A;  3CWT A;  2NOH A;  3OYE A;  1M3Q A;  4E9E A;  2NOE A;  4UOB A;  1KG7 A;  5FRO A;  4BAC A;  4EA5 A;  3OYC A;  3OH9 A;  1PU6 A;  2NOB A;  2NOF A;  3OY9 A;  4YPR A;  1N39 A;  4EA4 A;  3OGD A;  1P59 A;  1ORN A;  4BDZ A;  1EBM A;  4DK9 A;  3OYK A;  4BE0 A;  4AI4 A;  1HU0 A;  2H56 A;  5DPK A;  1PVS A; 
#chains in the Genus database with same CATH homology
 3D4V A;  4UNF A;  5KN8 A;  1WEI A;  1LMZ A;  3F0Z A;  1RRQ A;  3I0W A;  2I5W A;  3CWS A;  1YQR A;  2OFI A;  1LWW A;  3FSP A;  4E9H A;  4OFH A;  1P7M A;  3F10 A;  1N3A A;  4E9F A;  1MUN A;  2JHJ A;  3IHO A;  1YQM A;  1KG4 A;  4EVV A;  3CWA A;  3IH7 A;  4HSB A;  1N3C A;  3CW7 A;  1XQO A;  3FHG A;  3CVS A;  4EJZ A;  1XG7 A;  3N5N X;  2YG8 A;  1RRS A;  2XHI A;  5AN4 A;  4EW0 A;  1KEA A;  3N0U A;  3KTU A;  3CVT A;  4PII A;  1MUY A;  1NKU A;  2YG9 A;  1NGN A;  2JHN A;  1LWY A;  1LWV A;  3OH6 A;  4B23 A;  5KN9 A;  1KG3 A;  5CHZ A;  1KG2 A;  1YQK A;  4EJY A;  1PU7 A;  4OFE A;  1KO9 A;  1VRL A;  2NOL A;  3G0Q A;  4AIA A;  4AI5 A;  1DIZ A;  4EW4 A;  1YQL A;  3CWU A;  1FN7 A;  1MPG A;  1XQP A;  3I0X A;  2OFK A;  2NOZ A;  1PU8 A;  4E9G A;  3FHF A;  2ABK A;  1M3H A;  1KG5 A;  4B24 A;  1WEG A;  4B22 A;  1ORP A;  4YPH A;  4OFA A;  1MUD A;  2JG6 A;  1WEF A;  4YOQ A;  1KG6 A;  3S6I A;  3KNT A;  4B21 A;  2NOI A;  1KQJ A;  3CWT A;  2NOH A;  1M3Q A;  4E9E A;  2NOE A;  4UOB A;  1KG7 A;  4EA5 A;  3OH9 A;  1PU6 A;  2NOB A;  2NOF A;  4YPR A;  1N39 A;  4EA4 A;  3OGD A;  1P59 A;  1ORN A;  1EBM A;  4DK9 A;  4AI4 A;  1HU0 A;  2H56 A;  5DPK A;  1PVS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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