1KG2A

Crystal structure of the core fragment of muty from e.coli at 1.2a resolution
Total Genus 77
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
sequence length
224
structure length
224
Chain Sequence
MQASQFSAQVLDWYDKYGRKTLPWQIDKTPYKVWLSEVMLQQTQVATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGGKFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILDGNVKRVLARCYAVSGWPGKKEVENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSKPKCSLCPLQNGCIAAANNSWALYPGKKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords A/G-specific adenine glycosylase
publication title Analysis of the E.coli MutY DNA glycosylase structure and function by site-directed mutagenesis
rcsb
source organism Escherichia coli
molecule tags Hydrolase
total genus 77
structure length 224
sequence length 224
ec nomenclature ec 3.2.2.31: Adenine glycosylase.
pdb deposition date 2001-11-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00633 HHH Helix-hairpin-helix motif
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
A PF10576 EndIII_4Fe-2S Iron-sulfur binding domain of endonuclease III
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1kg2A02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1kg2A01
3CWSA 3G0QA 1MUDA 1PU6A 5KN9A 1YQRA 4OFEA 1LWWA 2NOFA 4PIIA 3CWAA 2OFKA 1ORNA 4EA5A 4OFAA 1MPGA 2XHIA 4UOBA 3CW7A 3FHFA 3CWUA 4B22A 1RRQA 1P59A 3OH6A 4OFHA 4YOQA 1NGNA 4AI4A 1PVSA 2NOZA 2YG9A 3N0UA 2NOHA 4YPHA 1XQPA 3OGDA 5KN8A 3CVSA 1KG4A 3I0XA 4E9EA 2H56A 1WEFA 3CVTA 4EW4A 4EJYA 2ABKA 5CHZA 2NOBA 5DPKA 1LWYA 3FHGA 2OFIA 3IHOA 3FSPA 1YQMA 1KG6A 2JHNA 1VRLA 2NOLA 1M3QA 1WEIA 3F0ZA 3N5NX 1KO9A 1YQKA 3D4VA 1NKUA 2JG6A 3OH9A 4UNFA 2NOEA 3I0WA 1M3HA 1P7MA 4E9GA 4AIAA 3KTUA 2NOIA 1XQOA 1KG7A 1EBMA 1N3AA 1KQJA 4EJZA 1MUYA 1MUNA 4E9FA 1KG2A 1ORPA 1KG3A 3S6IA 4EVVA 1FN7A 1LMZA 4EA4A 1PU7A 4B21A 1DIZA 1YQLA 4DK9A 4E9HA 1PU8A 1KG5A 1N39A 4B23A 4AI5A 2JHJA 1RRSA 4YPRA 1N3CA 1KEAA 2I5WA 1XG7A 3IH7A 4EW0A 1LWVA 3F10A 1HU0A 4B24A 3KNTA 4HSBA 2YG8A 3CWTA 5AN4A 1WEGA
chains in the Genus database with same CATH superfamily
3CWSA 3G0QA 1MUDA 1PU6A 5KN9A 1YQRA 4E7HA 4OFEA 1LWWA 3OYMA 2NOFA 4PIIA 3CWAA 2OFKA 1ORNA 4EA5A 4OFAA 1MPGA 2XHIA 3VW4A 4UOBA 3CW7A 3FHFA 2W04A 3S3NA 3CWUA 4B22A 1RRQA 3LCNA 1P59A 3OH6A 4OFHA 4YOQA 5FRMA 5FROA 4E7LA 1NGNA 4AI4A 1PVSA 2NOZA 2YG9A 3N0UA 3OYGA 2NOHA 4BE0A 4YPHA 3OYFA 4IKFA 3L2RA 2V75A 1XQPA 3OGDA 5KN8A 3CVSA 1U84A 3OYIA 1KG4A 3I0XA 4E9EA 4NZGA 2H56A 3OS2A 3OYCA 4BE1A 1WEFA 3NNQA 3CVTA 4EW4A 4ZTJA 4EJYA 2ABKA 4E7JA 5CHZA 2NOBA 5DPKA 3L2WA 1LWYA 3FHGA 2OFIA 3IHOA 3FSPA 1YQMA 1KG6A 2JHNA 1VRLA 2NOLA 1M3QA 1WEIA 3F0ZA 3N5NX 4BDYA 3OYBA 1KO9A 2JPSA 1YQKA 3D4VA 1NKUA 4E7KA 3R2XC 2JG6A 3OYJA 4UNFA 3OS1A 3OH9A 2NOEA 3I0WA 1M3HA 1P7MA 4E9GA 4AIAA 3KTUA 2NOIA 1XQOA 3OYEA 1KG7A 1EBMA 5FRNA 1N3AA 1KQJA 4EJZA 3OYAA 1MUYA 1MUNA 4E9FA 1KG2A 2W03A 1KG3A 1ORPA 3S6IA 4EVVA 1FN7A 1LMZA 4EA4A 1PU7A 4B21A 1DIZA 1YQLA 4BDZA 4DK9A 4E9HA 1PU8A 1KG5A 3S3OA 1N39A 4BACA 3OYKA 3L2VA 4B23A 4AI5A 3OYDA 2JHJA 3OY9A 1RRSA 4YPRA 1N3CA 1KEAA 2I5WA 3OS0A 3OYNA 3S3MA 3OYHA 4ZTFA 1XG7A 3IH7A 3L2QA 3L2UA 4EW0A 1LWVA 3F10A 1HU0A 4B24A 3OYLA 3KNTA 4HSBA 2YG8A 3CWTA 4E7IA 5AN4A 4BE2A 1WEGA
chains in the Genus database with same CATH topology
3CWSA 3G0QA 1MUDA 1PU6A 5KN9A 1YQRA 4OFEA 1LWWA 2NOFA 4PIIA 3CWAA 2OFKA 1ORNA 4EA5A 4OFAA 1MPGA 2XHIA 4UOBA 3CW7A 3FHFA 3CWUA 4B22A 1RRQA 1P59A 3OH6A 4OFHA 4YOQA 1NGNA 4AI4A 1PVSA 2NOZA 2YG9A 3N0UA 2NOHA 4YPHA 1XQPA 3OGDA 5KN8A 3CVSA 1KG4A 3I0XA 4E9EA 2H56A 1WEFA 3CVTA 4EW4A 4EJYA 2ABKA 5CHZA 2NOBA 5DPKA 1LWYA 3FHGA 2OFIA 3IHOA 3FSPA 1YQMA 1KG6A 2JHNA 1VRLA 2NOLA 1M3QA 1WEIA 3F0ZA 3N5NX 1KO9A 1YQKA 3D4VA 1NKUA 2JG6A 3OH9A 4UNFA 2NOEA 3I0WA 1M3HA 1P7MA 4E9GA 4AIAA 3KTUA 2NOIA 1XQOA 1KG7A 1EBMA 1N3AA 1KQJA 4EJZA 1MUYA 1MUNA 4E9FA 1KG2A 1ORPA 1KG3A 3S6IA 4EVVA 1FN7A 1LMZA 4EA4A 1PU7A 4B21A 1DIZA 1YQLA 4DK9A 4E9HA 1PU8A 1KG5A 1N39A 4B23A 4AI5A 2JHJA 1RRSA 4YPRA 1N3CA 1KEAA 2I5WA 1XG7A 3IH7A 4EW0A 1LWVA 3F10A 1HU0A 4B24A 3KNTA 4HSBA 2YG8A 3CWTA 5AN4A 1WEGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CWS A;  3G0Q A;  1MUD A;  1PU6 A;  5KN9 A;  1YQR A;  4OFE A;  1LWW A;  2NOF A;  4PII A;  3CWA A;  2OFK A;  1ORN A;  4EA5 A;  4OFA A;  1MPG A;  2XHI A;  4UOB A;  3CW7 A;  3FHF A;  3CWU A;  4B22 A;  1RRQ A;  1P59 A;  3OH6 A;  4OFH A;  4YOQ A;  1NGN A;  4AI4 A;  1PVS A;  2NOZ A;  2YG9 A;  3N0U A;  2NOH A;  4YPH A;  1XQP A;  3OGD A;  5KN8 A;  3CVS A;  1KG4 A;  3I0X A;  4E9E A;  2H56 A;  1WEF A;  3CVT A;  4EW4 A;  4EJY A;  2ABK A;  5CHZ A;  2NOB A;  5DPK A;  1LWY A;  3FHG A;  2OFI A;  3IHO A;  3FSP A;  1YQM A;  1KG6 A;  2JHN A;  1VRL A;  2NOL A;  1M3Q A;  1WEI A;  3F0Z A;  3N5N X;  1KO9 A;  1YQK A;  3D4V A;  1NKU A;  2JG6 A;  3OH9 A;  4UNF A;  2NOE A;  3I0W A;  1M3H A;  1P7M A;  4E9G A;  4AIA A;  3KTU A;  2NOI A;  1XQO A;  1KG7 A;  1EBM A;  1N3A A;  1KQJ A;  4EJZ A;  1MUY A;  1MUN A;  4E9F A;  1KG2 A;  1ORP A;  1KG3 A;  3S6I A;  4EVV A;  1FN7 A;  1LMZ A;  4EA4 A;  1PU7 A;  4B21 A;  1DIZ A;  1YQL A;  4DK9 A;  4E9H A;  1PU8 A;  1KG5 A;  1N39 A;  4B23 A;  4AI5 A;  2JHJ A;  1RRS A;  4YPR A;  1N3C A;  1KEA A;  2I5W A;  1XG7 A;  3IH7 A;  4EW0 A;  1LWV A;  3F10 A;  1HU0 A;  4B24 A;  3KNT A;  4HSB A;  2YG8 A;  3CWT A;  5AN4 A;  1WEG A; 
#chains in the Genus database with same CATH topology
 3CWS A;  3G0Q A;  1MUD A;  1PU6 A;  5KN9 A;  1YQR A;  4E7H A;  4OFE A;  1LWW A;  3OYM A;  2NOF A;  4PII A;  3CWA A;  2OFK A;  1ORN A;  4EA5 A;  4OFA A;  1MPG A;  2XHI A;  3VW4 A;  4UOB A;  3CW7 A;  3FHF A;  2W04 A;  3S3N A;  3CWU A;  4B22 A;  1RRQ A;  3LCN A;  1P59 A;  3OH6 A;  4OFH A;  4YOQ A;  5FRM A;  5FRO A;  4E7L A;  1NGN A;  4AI4 A;  1PVS A;  2NOZ A;  2YG9 A;  3N0U A;  3OYG A;  2NOH A;  4BE0 A;  4YPH A;  3OYF A;  4IKF A;  3L2R A;  2V75 A;  1XQP A;  3OGD A;  5KN8 A;  3CVS A;  1U84 A;  3OYI A;  1KG4 A;  3I0X A;  4E9E A;  4NZG A;  2H56 A;  3OS2 A;  3OYC A;  4BE1 A;  1WEF A;  3NNQ A;  3CVT A;  4EW4 A;  4ZTJ A;  4EJY A;  2ABK A;  4E7J A;  5CHZ A;  2NOB A;  5DPK A;  3L2W A;  1LWY A;  3FHG A;  2OFI A;  3IHO A;  3FSP A;  1YQM A;  1KG6 A;  2JHN A;  1VRL A;  2NOL A;  1M3Q A;  1WEI A;  3F0Z A;  3N5N X;  4BDY A;  3OYB A;  1KO9 A;  2JPS A;  1YQK A;  3D4V A;  1NKU A;  4E7K A;  3R2X C;  2JG6 A;  3OYJ A;  4UNF A;  3OS1 A;  3OH9 A;  2NOE A;  3I0W A;  1M3H A;  1P7M A;  4E9G A;  4AIA A;  3KTU A;  2NOI A;  1XQO A;  3OYE A;  1KG7 A;  1EBM A;  5FRN A;  1N3A A;  1KQJ A;  4EJZ A;  3OYA A;  1MUY A;  1MUN A;  4E9F A;  1KG2 A;  2W03 A;  1KG3 A;  1ORP A;  3S6I A;  4EVV A;  1FN7 A;  1LMZ A;  4EA4 A;  1PU7 A;  4B21 A;  1DIZ A;  1YQL A;  4BDZ A;  4DK9 A;  4E9H A;  1PU8 A;  1KG5 A;  3S3O A;  1N39 A;  4BAC A;  3OYK A;  3L2V A;  4B23 A;  4AI5 A;  3OYD A;  2JHJ A;  3OY9 A;  1RRS A;  4YPR A;  1N3C A;  1KEA A;  2I5W A;  3OS0 A;  3OYN A;  3S3M A;  3OYH A;  4ZTF A;  1XG7 A;  3IH7 A;  3L2Q A;  3L2U A;  4EW0 A;  1LWV A;  3F10 A;  1HU0 A;  4B24 A;  3OYL A;  3KNT A;  4HSB A;  2YG8 A;  3CWT A;  4E7I A;  5AN4 A;  4BE2 A;  1WEG A; 
#chains in the Genus database with same CATH homology
 3CWS A;  3G0Q A;  1MUD A;  1PU6 A;  5KN9 A;  1YQR A;  4OFE A;  1LWW A;  2NOF A;  4PII A;  3CWA A;  2OFK A;  1ORN A;  4EA5 A;  4OFA A;  1MPG A;  2XHI A;  4UOB A;  3CW7 A;  3FHF A;  3CWU A;  4B22 A;  1RRQ A;  1P59 A;  3OH6 A;  4OFH A;  4YOQ A;  1NGN A;  4AI4 A;  1PVS A;  2NOZ A;  2YG9 A;  3N0U A;  2NOH A;  4YPH A;  1XQP A;  3OGD A;  5KN8 A;  3CVS A;  1KG4 A;  3I0X A;  4E9E A;  2H56 A;  1WEF A;  3CVT A;  4EW4 A;  4EJY A;  2ABK A;  5CHZ A;  2NOB A;  5DPK A;  1LWY A;  3FHG A;  2OFI A;  3IHO A;  3FSP A;  1YQM A;  1KG6 A;  2JHN A;  1VRL A;  2NOL A;  1M3Q A;  1WEI A;  3F0Z A;  3N5N X;  1KO9 A;  1YQK A;  3D4V A;  1NKU A;  2JG6 A;  3OH9 A;  4UNF A;  2NOE A;  3I0W A;  1M3H A;  1P7M A;  4E9G A;  4AIA A;  3KTU A;  2NOI A;  1XQO A;  1KG7 A;  1EBM A;  1N3A A;  1KQJ A;  4EJZ A;  1MUY A;  1MUN A;  4E9F A;  1KG2 A;  1ORP A;  1KG3 A;  3S6I A;  4EVV A;  1FN7 A;  1LMZ A;  4EA4 A;  1PU7 A;  4B21 A;  1DIZ A;  1YQL A;  4DK9 A;  4E9H A;  1PU8 A;  1KG5 A;  1N39 A;  4B23 A;  4AI5 A;  2JHJ A;  1RRS A;  4YPR A;  1N3C A;  1KEA A;  2I5W A;  1XG7 A;  3IH7 A;  4EW0 A;  1LWV A;  3F10 A;  1HU0 A;  4B24 A;  3KNT A;  4HSB A;  2YG8 A;  3CWT A;  5AN4 A;  1WEG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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