1KG3A

Crystal structure of the core fragment of muty from e.coli at 1.55a resolution
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
224
structure length
224
Chain Sequence
MQASQFSAQVLDWYDKYGRKTLPWQIDKTPYKVWLSEVMLQQTQVATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGGKFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILDGNVKRVLARCYAVSGWPGKKEVENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSKPKCSLCPLQNGCIAAANNSWALYPGKKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords A/G-specific adenine glycosylase
publication title Analysis of the E.coli MutY DNA glycosylase structure and function by site-directed mutagenesis
rcsb
source organism Escherichia coli
molecule tags Hydrolase
total genus 81
structure length 224
sequence length 224
ec nomenclature ec 3.2.2.31: Adenine glycosylase.
pdb deposition date 2001-11-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00633 HHH Helix-hairpin-helix motif
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
A PF10576 EndIII_4Fe-2S Iron-sulfur binding domain of endonuclease III
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1kg3A02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1kg3A01
1NKUA 4UNFA 3OH6A 4AI4A 3CVSA 3F10A 1WEGA 3FHFA 4EJYA 1NGNA 4EA5A 1N39A 3KTUA 2JHNA 4YPHA 3CW7A 4DK9A 1ORNA 4OFHA 2OFIA 1MPGA 1RRQA 2NOEA 5KN9A 2YG8A 3CWAA 1ORPA 1P59A 1LWYA 1PU6A 4B22A 3FHGA 4B24A 1VRLA 1WEIA 1M3QA 1M3HA 4EA4A 1XQPA 1DIZA 3F0ZA 4PIIA 4YOQA 4EW4A 1KG6A 2NOLA 3CWTA 5CHZA 1LWWA 4AI5A 3FSPA 1KQJA 3D4VA 1KG3A 3G0QA 1YQMA 2OFKA 1FN7A 2NOZA 4YPRA 3N5NX 2I5WA 1LWVA 2H56A 3I0WA 4E9EA 1XG7A 5DPKA 3KNTA 1MUDA 1PU8A 4EVVA 3S6IA 4B23A 3OH9A 1XQOA 2JG6A 4EJZA 1MUYA 1PU7A 1HU0A 4E9FA 3IHOA 3CVTA 1KG7A 1LMZA 3IH7A 1N3AA 4E9GA 1YQLA 1KEAA 1KG4A 1RRSA 1KO9A 1MUNA 3N0UA 4UOBA 3OGDA 3CWUA 2NOFA 2JHJA 4HSBA 5AN4A 2YG9A 5KN8A 2XHIA 2NOIA 1N3CA 1EBMA 1YQRA 4OFEA 1WEFA 2ABKA 3I0XA 1KG2A 4E9HA 2NOBA 1P7MA 4OFAA 2NOHA 1YQKA 4AIAA 1PVSA 4B21A 3CWSA 1KG5A 4EW0A
chains in the Genus database with same CATH superfamily
3S3OA 4ZTJA 1NKUA 4UNFA 3OH6A 2JPSA 4AI4A 3CVSA 3F10A 1WEGA 3FHFA 4EJYA 1NGNA 4EA5A 3OYCA 1N39A 3KTUA 2W04A 2JHNA 4YPHA 3CW7A 4DK9A 1ORNA 4OFHA 2OFIA 1MPGA 3S3NA 1RRQA 2NOEA 5KN9A 2V75A 2YG8A 3CWAA 1ORPA 3OS0A 1P59A 1LWYA 1PU6A 4B22A 3FHGA 5FRMA 4B24A 1VRLA 1WEIA 4E7JA 1M3QA 1M3HA 4EA4A 4BACA 1XQPA 1DIZA 3F0ZA 4PIIA 4YOQA 4EW4A 3L2QA 5FROA 1KG6A 3R2XC 2NOLA 3CWTA 5CHZA 1LWWA 4AI5A 3OYLA 3FSPA 4BE1A 1KQJA 3D4VA 1KG3A 3G0QA 3L2VA 1YQMA 2OFKA 1FN7A 2NOZA 4YPRA 3N5NX 4E7LA 2I5WA 3OYNA 3OS2A 1LWVA 2H56A 3I0WA 4E9EA 1XG7A 4NZGA 5DPKA 3NNQA 3OYIA 3KNTA 4BDZA 3LCNA 3OYKA 1MUDA 3OYBA 1PU8A 4EVVA 3S6IA 4B23A 3OH9A 1XQOA 2JG6A 4EJZA 1MUYA 1PU7A 1HU0A 3OYAA 4E9FA 3OYMA 4E7IA 3IHOA 3OYGA 1KG7A 3L2UA 3CVTA 1U84A 1LMZA 3IH7A 1N3AA 4IKFA 3L2WA 4BE0A 4E9GA 1YQLA 1KEAA 1KG4A 1RRSA 1KO9A 1MUNA 3OYJA 3N0UA 4UOBA 4BDYA 3OGDA 3CWUA 2NOFA 2JHJA 4E7KA 4HSBA 5AN4A 3OYFA 2YG9A 3OS1A 5KN8A 3OY9A 2XHIA 3OYEA 2NOIA 4E7HA 1N3CA 1EBMA 3VW4A 1YQRA 3OYHA 4OFEA 1WEFA 2ABKA 3I0XA 1KG2A 4BE2A 4E9HA 2NOBA 3S3MA 1P7MA 4OFAA 3OYDA 2NOHA 1YQKA 4AIAA 4ZTFA 1PVSA 3L2RA 5FRNA 4B21A 3CWSA 1KG5A 4EW0A 2W03A
chains in the Genus database with same CATH topology
1NKUA 4UNFA 3OH6A 4AI4A 3CVSA 3F10A 1WEGA 3FHFA 4EJYA 1NGNA 4EA5A 1N39A 3KTUA 2JHNA 4YPHA 3CW7A 4DK9A 1ORNA 4OFHA 2OFIA 1MPGA 1RRQA 2NOEA 5KN9A 2YG8A 3CWAA 1ORPA 1P59A 1LWYA 1PU6A 4B22A 3FHGA 4B24A 1VRLA 1WEIA 1M3QA 1M3HA 4EA4A 1XQPA 1DIZA 3F0ZA 4PIIA 4YOQA 4EW4A 1KG6A 2NOLA 3CWTA 5CHZA 1LWWA 4AI5A 3FSPA 1KQJA 3D4VA 1KG3A 3G0QA 1YQMA 2OFKA 1FN7A 2NOZA 4YPRA 3N5NX 2I5WA 1LWVA 2H56A 3I0WA 4E9EA 1XG7A 5DPKA 3KNTA 1MUDA 1PU8A 4EVVA 3S6IA 4B23A 3OH9A 1XQOA 2JG6A 4EJZA 1MUYA 1PU7A 1HU0A 4E9FA 3IHOA 3CVTA 1KG7A 1LMZA 3IH7A 1N3AA 4E9GA 1YQLA 1KEAA 1KG4A 1RRSA 1KO9A 1MUNA 3N0UA 4UOBA 3OGDA 3CWUA 2NOFA 2JHJA 4HSBA 5AN4A 2YG9A 5KN8A 2XHIA 2NOIA 1N3CA 1EBMA 1YQRA 4OFEA 1WEFA 2ABKA 3I0XA 1KG2A 4E9HA 2NOBA 1P7MA 4OFAA 2NOHA 1YQKA 4AIAA 1PVSA 4B21A 3CWSA 1KG5A 4EW0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NKU A;  4UNF A;  3OH6 A;  4AI4 A;  3CVS A;  3F10 A;  1WEG A;  3FHF A;  4EJY A;  1NGN A;  4EA5 A;  1N39 A;  3KTU A;  2JHN A;  4YPH A;  3CW7 A;  4DK9 A;  1ORN A;  4OFH A;  2OFI A;  1MPG A;  1RRQ A;  2NOE A;  5KN9 A;  2YG8 A;  3CWA A;  1ORP A;  1P59 A;  1LWY A;  1PU6 A;  4B22 A;  3FHG A;  4B24 A;  1VRL A;  1WEI A;  1M3Q A;  1M3H A;  4EA4 A;  1XQP A;  1DIZ A;  3F0Z A;  4PII A;  4YOQ A;  4EW4 A;  1KG6 A;  2NOL A;  3CWT A;  5CHZ A;  1LWW A;  4AI5 A;  3FSP A;  1KQJ A;  3D4V A;  1KG3 A;  3G0Q A;  1YQM A;  2OFK A;  1FN7 A;  2NOZ A;  4YPR A;  3N5N X;  2I5W A;  1LWV A;  2H56 A;  3I0W A;  4E9E A;  1XG7 A;  5DPK A;  3KNT A;  1MUD A;  1PU8 A;  4EVV A;  3S6I A;  4B23 A;  3OH9 A;  1XQO A;  2JG6 A;  4EJZ A;  1MUY A;  1PU7 A;  1HU0 A;  4E9F A;  3IHO A;  3CVT A;  1KG7 A;  1LMZ A;  3IH7 A;  1N3A A;  4E9G A;  1YQL A;  1KEA A;  1KG4 A;  1RRS A;  1KO9 A;  1MUN A;  3N0U A;  4UOB A;  3OGD A;  3CWU A;  2NOF A;  2JHJ A;  4HSB A;  5AN4 A;  2YG9 A;  5KN8 A;  2XHI A;  2NOI A;  1N3C A;  1EBM A;  1YQR A;  4OFE A;  1WEF A;  2ABK A;  3I0X A;  1KG2 A;  4E9H A;  2NOB A;  1P7M A;  4OFA A;  2NOH A;  1YQK A;  4AIA A;  1PVS A;  4B21 A;  3CWS A;  1KG5 A;  4EW0 A; 
#chains in the Genus database with same CATH topology
 3S3O A;  4ZTJ A;  1NKU A;  4UNF A;  3OH6 A;  2JPS A;  4AI4 A;  3CVS A;  3F10 A;  1WEG A;  3FHF A;  4EJY A;  1NGN A;  4EA5 A;  3OYC A;  1N39 A;  3KTU A;  2W04 A;  2JHN A;  4YPH A;  3CW7 A;  4DK9 A;  1ORN A;  4OFH A;  2OFI A;  1MPG A;  3S3N A;  1RRQ A;  2NOE A;  5KN9 A;  2V75 A;  2YG8 A;  3CWA A;  1ORP A;  3OS0 A;  1P59 A;  1LWY A;  1PU6 A;  4B22 A;  3FHG A;  5FRM A;  4B24 A;  1VRL A;  1WEI A;  4E7J A;  1M3Q A;  1M3H A;  4EA4 A;  4BAC A;  1XQP A;  1DIZ A;  3F0Z A;  4PII A;  4YOQ A;  4EW4 A;  3L2Q A;  5FRO A;  1KG6 A;  3R2X C;  2NOL A;  3CWT A;  5CHZ A;  1LWW A;  4AI5 A;  3OYL A;  3FSP A;  4BE1 A;  1KQJ A;  3D4V A;  1KG3 A;  3G0Q A;  3L2V A;  1YQM A;  2OFK A;  1FN7 A;  2NOZ A;  4YPR A;  3N5N X;  4E7L A;  2I5W A;  3OYN A;  3OS2 A;  1LWV A;  2H56 A;  3I0W A;  4E9E A;  1XG7 A;  4NZG A;  5DPK A;  3NNQ A;  3OYI A;  3KNT A;  4BDZ A;  3LCN A;  3OYK A;  1MUD A;  3OYB A;  1PU8 A;  4EVV A;  3S6I A;  4B23 A;  3OH9 A;  1XQO A;  2JG6 A;  4EJZ A;  1MUY A;  1PU7 A;  1HU0 A;  3OYA A;  4E9F A;  3OYM A;  4E7I A;  3IHO A;  3OYG A;  1KG7 A;  3L2U A;  3CVT A;  1U84 A;  1LMZ A;  3IH7 A;  1N3A A;  4IKF A;  3L2W A;  4BE0 A;  4E9G A;  1YQL A;  1KEA A;  1KG4 A;  1RRS A;  1KO9 A;  1MUN A;  3OYJ A;  3N0U A;  4UOB A;  4BDY A;  3OGD A;  3CWU A;  2NOF A;  2JHJ A;  4E7K A;  4HSB A;  5AN4 A;  3OYF A;  2YG9 A;  3OS1 A;  5KN8 A;  3OY9 A;  2XHI A;  3OYE A;  2NOI A;  4E7H A;  1N3C A;  1EBM A;  3VW4 A;  1YQR A;  3OYH A;  4OFE A;  1WEF A;  2ABK A;  3I0X A;  1KG2 A;  4BE2 A;  4E9H A;  2NOB A;  3S3M A;  1P7M A;  4OFA A;  3OYD A;  2NOH A;  1YQK A;  4AIA A;  4ZTF A;  1PVS A;  3L2R A;  5FRN A;  4B21 A;  3CWS A;  1KG5 A;  4EW0 A;  2W03 A; 
#chains in the Genus database with same CATH homology
 1NKU A;  4UNF A;  3OH6 A;  4AI4 A;  3CVS A;  3F10 A;  1WEG A;  3FHF A;  4EJY A;  1NGN A;  4EA5 A;  1N39 A;  3KTU A;  2JHN A;  4YPH A;  3CW7 A;  4DK9 A;  1ORN A;  4OFH A;  2OFI A;  1MPG A;  1RRQ A;  2NOE A;  5KN9 A;  2YG8 A;  3CWA A;  1ORP A;  1P59 A;  1LWY A;  1PU6 A;  4B22 A;  3FHG A;  4B24 A;  1VRL A;  1WEI A;  1M3Q A;  1M3H A;  4EA4 A;  1XQP A;  1DIZ A;  3F0Z A;  4PII A;  4YOQ A;  4EW4 A;  1KG6 A;  2NOL A;  3CWT A;  5CHZ A;  1LWW A;  4AI5 A;  3FSP A;  1KQJ A;  3D4V A;  1KG3 A;  3G0Q A;  1YQM A;  2OFK A;  1FN7 A;  2NOZ A;  4YPR A;  3N5N X;  2I5W A;  1LWV A;  2H56 A;  3I0W A;  4E9E A;  1XG7 A;  5DPK A;  3KNT A;  1MUD A;  1PU8 A;  4EVV A;  3S6I A;  4B23 A;  3OH9 A;  1XQO A;  2JG6 A;  4EJZ A;  1MUY A;  1PU7 A;  1HU0 A;  4E9F A;  3IHO A;  3CVT A;  1KG7 A;  1LMZ A;  3IH7 A;  1N3A A;  4E9G A;  1YQL A;  1KEA A;  1KG4 A;  1RRS A;  1KO9 A;  1MUN A;  3N0U A;  4UOB A;  3OGD A;  3CWU A;  2NOF A;  2JHJ A;  4HSB A;  5AN4 A;  2YG9 A;  5KN8 A;  2XHI A;  2NOI A;  1N3C A;  1EBM A;  1YQR A;  4OFE A;  1WEF A;  2ABK A;  3I0X A;  1KG2 A;  4E9H A;  2NOB A;  1P7M A;  4OFA A;  2NOH A;  1YQK A;  4AIA A;  1PVS A;  4B21 A;  3CWS A;  1KG5 A;  4EW0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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