1KG3A

Crystal structure of the core fragment of muty from e.coli at 1.55a resolution
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
224
structure length
224
Chain Sequence
MQASQFSAQVLDWYDKYGRKTLPWQIDKTPYKVWLSEVMLQQTQVATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGGKFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILDGNVKRVLARCYAVSGWPGKKEVENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSKPKCSLCPLQNGCIAAANNSWALYPGKKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords A/G-specific adenine glycosylase
publication title Analysis of the E.coli MutY DNA glycosylase structure and function by site-directed mutagenesis
rcsb
source organism Escherichia coli
molecule tags Hydrolase
total genus 81
structure length 224
sequence length 224
ec nomenclature ec 3.2.2.31: Adenine glycosylase.
pdb deposition date 2001-11-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00633 HHH Helix-hairpin-helix motif
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
A PF10576 EndIII_4Fe-2S Iron-sulfur binding domain of endonuclease III
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1kg3A02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1kg3A01
2NOFA 2NOZA 1YQLA 2JG6A 2JHJA 4AIAA 4EW4A 1N3AA 3IH7A 1MUYA 5KN8A 1KG7A 4OFAA 1EBMA 1XQOA 3N5NX 1MUNA 3KTUA 1KEAA 1NGNA 4E9EA 1N39A 1PU6A 4B21A 3S6IA 1KQJA 3OH9A 4YPHA 3OGDA 4B23A 4OFHA 3D4VA 4E9HA 1WEFA 4EJZA 3FHFA 1P7MA 1DIZA 4AI4A 1ORPA 4EA4A 3F0ZA 2H56A 5CHZA 4UNFA 3OH6A 4E9GA 1KO9A 3I0XA 1KG6A 1RRSA 3I0WA 4EA5A 2JHNA 4B22A 2NOIA 1M3QA 2XHIA 3CVSA 3G0QA 3CWSA 1YQRA 1PU8A 1FN7A 4EJYA 1MPGA 1XG7A 2NOEA 4EVVA 1LWVA 5AN4A 1ORNA 1LWYA 3CVTA 1LWWA 5DPKA 4EW0A 3FHGA 4HSBA 1KG2A 1RRQA 2I5WA 4AI5A 3KNTA 1NKUA 1KG5A 2NOLA 1P59A 4B24A 1LMZA 2NOBA 1XQPA 5KN9A 3CW7A 4YOQA 1N3CA 4PIIA 1HU0A 4E9FA 1M3HA 1KG4A 2ABKA 2NOHA 4DK9A 3N0UA 1WEGA 2YG9A 2YG8A 3FSPA 1VRLA 2OFIA 1WEIA 3CWUA 2OFKA 4UOBA 4OFEA 1YQMA 3CWTA 3IHOA 1KG3A 1YQKA 1PU7A 4YPRA 3CWAA 1MUDA 1PVSA 3F10A
chains in the Genus database with same CATH superfamily
4BACA 4E7JA 3L2WA 2NOFA 4BDYA 5FRNA 2NOZA 1YQLA 4ZTFA 2JG6A 2JHJA 3L2RA 4AIAA 3OYDA 4EW4A 1N3AA 3IH7A 1MUYA 3L2QA 3NNQA 5KN8A 1KG7A 4OFAA 3OY9A 1XQOA 1EBMA 3N5NX 1MUNA 3OYMA 3KTUA 1KEAA 1NGNA 4E9EA 3OYIA 3OYNA 1PU6A 3OYEA 4B21A 1N39A 3S6IA 1KQJA 3OH9A 4YPHA 3OGDA 4B23A 4OFHA 5FRMA 3D4VA 4E9HA 1WEFA 3S3OA 3FHFA 4EJZA 3OYHA 1P7MA 4E7LA 3OYGA 3S3MA 1DIZA 4AI4A 1ORPA 4EA4A 4IKFA 3F0ZA 2H56A 5CHZA 3OYBA 3OYKA 4BE0A 4UNFA 3OH6A 4E9GA 1KO9A 3I0XA 1KG6A 5FROA 1RRSA 3I0WA 4EA5A 2JHNA 4B22A 2W03A 2NOIA 4ZTJA 1M3QA 2XHIA 3OYCA 3CVSA 4E7HA 3G0QA 3CWSA 1YQRA 1PU8A 1FN7A 3OS2A 4EJYA 1MPGA 1XG7A 2NOEA 4EVVA 3S3NA 5AN4A 1ORNA 3LCNA 1LWVA 1LWYA 3CVTA 1LWWA 4E7KA 5DPKA 4EW0A 2JPSA 3FHGA 4HSBA 1KG2A 1RRQA 3L2UA 2I5WA 3OYFA 1U84A 4AI5A 4BDZA 3KNTA 1NKUA 3OS1A 2V75A 1KG5A 2NOLA 1P59A 4B24A 1LMZA 4NZGA 2NOBA 1XQPA 5KN9A 3CW7A 4YOQA 3OS0A 3R2XC 1N3CA 4PIIA 1HU0A 3L2VA 4E9FA 3VW4A 3OYLA 4BE2A 1M3HA 1KG4A 2ABKA 2NOHA 4DK9A 4E7IA 3N0UA 1WEGA 2YG9A 2YG8A 3FSPA 1VRLA 2OFIA 1WEIA 3CWUA 2OFKA 4UOBA 4OFEA 1YQMA 3CWTA 3IHOA 2W04A 1KG3A 1YQKA 1PU7A 4YPRA 3OYAA 3OYJA 3CWAA 4BE1A 1MUDA 1PVSA 3F10A
chains in the Genus database with same CATH topology
2NOFA 2NOZA 1YQLA 2JG6A 2JHJA 4AIAA 4EW4A 1N3AA 3IH7A 1MUYA 5KN8A 1KG7A 4OFAA 1EBMA 1XQOA 3N5NX 1MUNA 3KTUA 1KEAA 1NGNA 4E9EA 1N39A 1PU6A 4B21A 3S6IA 1KQJA 3OH9A 4YPHA 3OGDA 4B23A 4OFHA 3D4VA 4E9HA 1WEFA 4EJZA 3FHFA 1P7MA 1DIZA 4AI4A 1ORPA 4EA4A 3F0ZA 2H56A 5CHZA 4UNFA 3OH6A 4E9GA 1KO9A 3I0XA 1KG6A 1RRSA 3I0WA 4EA5A 2JHNA 4B22A 2NOIA 1M3QA 2XHIA 3CVSA 3G0QA 3CWSA 1YQRA 1PU8A 1FN7A 4EJYA 1MPGA 1XG7A 2NOEA 4EVVA 1LWVA 5AN4A 1ORNA 1LWYA 3CVTA 1LWWA 5DPKA 4EW0A 3FHGA 4HSBA 1KG2A 1RRQA 2I5WA 4AI5A 3KNTA 1NKUA 1KG5A 2NOLA 1P59A 4B24A 1LMZA 2NOBA 1XQPA 5KN9A 3CW7A 4YOQA 1N3CA 4PIIA 1HU0A 4E9FA 1M3HA 1KG4A 2ABKA 2NOHA 4DK9A 3N0UA 1WEGA 2YG9A 2YG8A 3FSPA 1VRLA 2OFIA 1WEIA 3CWUA 2OFKA 4UOBA 4OFEA 1YQMA 3CWTA 3IHOA 1KG3A 1YQKA 1PU7A 4YPRA 3CWAA 1MUDA 1PVSA 3F10A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NOF A;  2NOZ A;  1YQL A;  2JG6 A;  2JHJ A;  4AIA A;  4EW4 A;  1N3A A;  3IH7 A;  1MUY A;  5KN8 A;  1KG7 A;  4OFA A;  1EBM A;  1XQO A;  3N5N X;  1MUN A;  3KTU A;  1KEA A;  1NGN A;  4E9E A;  1N39 A;  1PU6 A;  4B21 A;  3S6I A;  1KQJ A;  3OH9 A;  4YPH A;  3OGD A;  4B23 A;  4OFH A;  3D4V A;  4E9H A;  1WEF A;  4EJZ A;  3FHF A;  1P7M A;  1DIZ A;  4AI4 A;  1ORP A;  4EA4 A;  3F0Z A;  2H56 A;  5CHZ A;  4UNF A;  3OH6 A;  4E9G A;  1KO9 A;  3I0X A;  1KG6 A;  1RRS A;  3I0W A;  4EA5 A;  2JHN A;  4B22 A;  2NOI A;  1M3Q A;  2XHI A;  3CVS A;  3G0Q A;  3CWS A;  1YQR A;  1PU8 A;  1FN7 A;  4EJY A;  1MPG A;  1XG7 A;  2NOE A;  4EVV A;  1LWV A;  5AN4 A;  1ORN A;  1LWY A;  3CVT A;  1LWW A;  5DPK A;  4EW0 A;  3FHG A;  4HSB A;  1KG2 A;  1RRQ A;  2I5W A;  4AI5 A;  3KNT A;  1NKU A;  1KG5 A;  2NOL A;  1P59 A;  4B24 A;  1LMZ A;  2NOB A;  1XQP A;  5KN9 A;  3CW7 A;  4YOQ A;  1N3C A;  4PII A;  1HU0 A;  4E9F A;  1M3H A;  1KG4 A;  2ABK A;  2NOH A;  4DK9 A;  3N0U A;  1WEG A;  2YG9 A;  2YG8 A;  3FSP A;  1VRL A;  2OFI A;  1WEI A;  3CWU A;  2OFK A;  4UOB A;  4OFE A;  1YQM A;  3CWT A;  3IHO A;  1KG3 A;  1YQK A;  1PU7 A;  4YPR A;  3CWA A;  1MUD A;  1PVS A;  3F10 A; 
#chains in the Genus database with same CATH topology
 4BAC A;  4E7J A;  3L2W A;  2NOF A;  4BDY A;  5FRN A;  2NOZ A;  1YQL A;  4ZTF A;  2JG6 A;  2JHJ A;  3L2R A;  4AIA A;  3OYD A;  4EW4 A;  1N3A A;  3IH7 A;  1MUY A;  3L2Q A;  3NNQ A;  5KN8 A;  1KG7 A;  4OFA A;  3OY9 A;  1XQO A;  1EBM A;  3N5N X;  1MUN A;  3OYM A;  3KTU A;  1KEA A;  1NGN A;  4E9E A;  3OYI A;  3OYN A;  1PU6 A;  3OYE A;  4B21 A;  1N39 A;  3S6I A;  1KQJ A;  3OH9 A;  4YPH A;  3OGD A;  4B23 A;  4OFH A;  5FRM A;  3D4V A;  4E9H A;  1WEF A;  3S3O A;  3FHF A;  4EJZ A;  3OYH A;  1P7M A;  4E7L A;  3OYG A;  3S3M A;  1DIZ A;  4AI4 A;  1ORP A;  4EA4 A;  4IKF A;  3F0Z A;  2H56 A;  5CHZ A;  3OYB A;  3OYK A;  4BE0 A;  4UNF A;  3OH6 A;  4E9G A;  1KO9 A;  3I0X A;  1KG6 A;  5FRO A;  1RRS A;  3I0W A;  4EA5 A;  2JHN A;  4B22 A;  2W03 A;  2NOI A;  4ZTJ A;  1M3Q A;  2XHI A;  3OYC A;  3CVS A;  4E7H A;  3G0Q A;  3CWS A;  1YQR A;  1PU8 A;  1FN7 A;  3OS2 A;  4EJY A;  1MPG A;  1XG7 A;  2NOE A;  4EVV A;  3S3N A;  5AN4 A;  1ORN A;  3LCN A;  1LWV A;  1LWY A;  3CVT A;  1LWW A;  4E7K A;  5DPK A;  4EW0 A;  2JPS A;  3FHG A;  4HSB A;  1KG2 A;  1RRQ A;  3L2U A;  2I5W A;  3OYF A;  1U84 A;  4AI5 A;  4BDZ A;  3KNT A;  1NKU A;  3OS1 A;  2V75 A;  1KG5 A;  2NOL A;  1P59 A;  4B24 A;  1LMZ A;  4NZG A;  2NOB A;  1XQP A;  5KN9 A;  3CW7 A;  4YOQ A;  3OS0 A;  3R2X C;  1N3C A;  4PII A;  1HU0 A;  3L2V A;  4E9F A;  3VW4 A;  3OYL A;  4BE2 A;  1M3H A;  1KG4 A;  2ABK A;  2NOH A;  4DK9 A;  4E7I A;  3N0U A;  1WEG A;  2YG9 A;  2YG8 A;  3FSP A;  1VRL A;  2OFI A;  1WEI A;  3CWU A;  2OFK A;  4UOB A;  4OFE A;  1YQM A;  3CWT A;  3IHO A;  2W04 A;  1KG3 A;  1YQK A;  1PU7 A;  4YPR A;  3OYA A;  3OYJ A;  3CWA A;  4BE1 A;  1MUD A;  1PVS A;  3F10 A; 
#chains in the Genus database with same CATH homology
 2NOF A;  2NOZ A;  1YQL A;  2JG6 A;  2JHJ A;  4AIA A;  4EW4 A;  1N3A A;  3IH7 A;  1MUY A;  5KN8 A;  1KG7 A;  4OFA A;  1EBM A;  1XQO A;  3N5N X;  1MUN A;  3KTU A;  1KEA A;  1NGN A;  4E9E A;  1N39 A;  1PU6 A;  4B21 A;  3S6I A;  1KQJ A;  3OH9 A;  4YPH A;  3OGD A;  4B23 A;  4OFH A;  3D4V A;  4E9H A;  1WEF A;  4EJZ A;  3FHF A;  1P7M A;  1DIZ A;  4AI4 A;  1ORP A;  4EA4 A;  3F0Z A;  2H56 A;  5CHZ A;  4UNF A;  3OH6 A;  4E9G A;  1KO9 A;  3I0X A;  1KG6 A;  1RRS A;  3I0W A;  4EA5 A;  2JHN A;  4B22 A;  2NOI A;  1M3Q A;  2XHI A;  3CVS A;  3G0Q A;  3CWS A;  1YQR A;  1PU8 A;  1FN7 A;  4EJY A;  1MPG A;  1XG7 A;  2NOE A;  4EVV A;  1LWV A;  5AN4 A;  1ORN A;  1LWY A;  3CVT A;  1LWW A;  5DPK A;  4EW0 A;  3FHG A;  4HSB A;  1KG2 A;  1RRQ A;  2I5W A;  4AI5 A;  3KNT A;  1NKU A;  1KG5 A;  2NOL A;  1P59 A;  4B24 A;  1LMZ A;  2NOB A;  1XQP A;  5KN9 A;  3CW7 A;  4YOQ A;  1N3C A;  4PII A;  1HU0 A;  4E9F A;  1M3H A;  1KG4 A;  2ABK A;  2NOH A;  4DK9 A;  3N0U A;  1WEG A;  2YG9 A;  2YG8 A;  3FSP A;  1VRL A;  2OFI A;  1WEI A;  3CWU A;  2OFK A;  4UOB A;  4OFE A;  1YQM A;  3CWT A;  3IHO A;  1KG3 A;  1YQK A;  1PU7 A;  4YPR A;  3CWA A;  1MUD A;  1PVS A;  3F10 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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