1KG3A

Crystal structure of the core fragment of muty from e.coli at 1.55a resolution
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
224
structure length
224
Chain Sequence
MQASQFSAQVLDWYDKYGRKTLPWQIDKTPYKVWLSEVMLQQTQVATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGGKFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILDGNVKRVLARCYAVSGWPGKKEVENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSKPKCSLCPLQNGCIAAANNSWALYPGKKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Analysis of the E.coli MutY DNA glycosylase structure and function by site-directed mutagenesis
rcsb
source organism Escherichia coli
molecule tags Hydrolase
molecule keywords A/G-specific adenine glycosylase
total genus 81
structure length 224
sequence length 224
ec nomenclature ec 3.2.2.31: Adenine glycosylase.
pdb deposition date 2001-11-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00633 HHH Helix-hairpin-helix motif
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
A PF10576 EndIII_4Fe-2S Iron-sulfur binding domain of endonuclease III
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1kg3A02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1kg3A01
3FHGA 2JG6A 1MUDA 1MUNA 1N3CA 4EVVA 1KG6A 3I0XA 4EJZA 2H56A 4YPRA 2JHNA 4PIIA 1KG3A 1M3QA 3OH6A 1VRLA 5CHZA 4AIAA 2NOZA 1PVSA 1EBMA 1NKUA 1ORPA 4HSBA 3CWUA 1RRSA 1N39A 1KG5A 3S6IA 3KNTA 1HU0A 1KG7A 4YOQA 3CW7A 1LWVA 4B23A 1FN7A 5KN9A 5DPKA 4E9EA 4UOBA 1XQPA 4B21A 1YQRA 3IHOA 3CWTA 1LMZA 2NOFA 1KQJA 4B22A 4E9FA 1LWYA 4YPHA 4OFHA 3OH9A 1YQLA 4AI4A 1WEGA 4OFEA 1P59A 2I5WA 1KO9A 1YQKA 2OFIA 1ORNA 4E9HA 4EJYA 1XQOA 2ABKA 3CVTA 1DIZA 1PU8A 4EA4A 1WEFA 2YG9A 1M3HA 2XHIA 3CWAA 2OFKA 1PU7A 3F10A 3CVSA 4EA5A 3D4VA 1N3AA 1WEIA 4EW4A 3N0UA 2NOIA 5AN4A 4EW0A 3OGDA 1KEAA 4B24A 2NOBA 1MUYA 4OFAA 2YG8A 3CWSA 3FHFA 2JHJA 1XG7A 1YQMA 5KN8A 4E9GA 4DK9A 2NOHA 1MPGA 1P7MA 1RRQA 3F0ZA 1NGNA 3FSPA 4UNFA 1KG2A 1LWWA 1PU6A 3N5NX 4AI5A 2NOEA 3G0QA 3IH7A 3I0WA 2NOLA 1KG4A 3KTUA
chains in the Genus database with same CATH superfamily
3LCNA 4E7KA 3FHGA 2JG6A 1MUDA 1MUNA 1N3CA 4EVVA 3S3OA 3VW4A 3L2UA 1KG6A 3OYLA 3I0XA 4BDYA 4EJZA 3NNQA 2H56A 5FROA 4YPRA 2JHNA 4PIIA 1KG3A 1M3QA 3OH6A 1VRLA 5CHZA 3OYAA 3OYNA 4BDZA 4AIAA 2NOZA 1PVSA 1EBMA 4E7HA 1NKUA 1ORPA 4HSBA 3CWUA 1RRSA 3L2QA 4E7LA 1KG5A 1N39A 3L2RA 3S6IA 3KNTA 1HU0A 1KG7A 4YOQA 3CW7A 1LWVA 4B23A 3OYDA 5KN9A 5DPKA 1FN7A 4E9EA 2W04A 4UOBA 1XQPA 4B21A 3OYEA 1YQRA 3IHOA 3OYJA 3CWTA 1LMZA 2NOFA 2V75A 1KQJA 3OS0A 4B22A 3OYFA 3R2XC 4E7IA 3OYHA 4E9FA 3OYBA 1LWYA 4YPHA 4BE0A 4OFHA 3OH9A 1YQLA 4AI4A 1WEGA 4OFEA 1P59A 2I5WA 1KO9A 3OYKA 1YQKA 3OYMA 2OFIA 4BE2A 1ORNA 4E9HA 4EJYA 1U84A 1XQOA 2ABKA 3CVTA 1DIZA 1PU8A 4EA4A 3OS1A 1WEFA 2YG9A 1M3HA 2XHIA 3CWAA 3OYCA 3OY9A 2OFKA 1PU7A 3F10A 3CVSA 4EA5A 4IKFA 4BE1A 3D4VA 2W03A 1N3AA 4ZTJA 1WEIA 4EW4A 4ZTFA 3N0UA 2NOIA 5AN4A 4EW0A 3OGDA 1KEAA 4B24A 4BACA 2NOBA 3OYIA 5FRMA 1MUYA 4OFAA 2YG8A 3CWSA 3FHFA 2JHJA 1XG7A 3L2WA 1YQMA 4NZGA 5KN8A 3S3NA 3S3MA 5FRNA 3OS2A 4E9GA 4DK9A 2NOHA 1MPGA 1P7MA 3OYGA 1RRQA 3F0ZA 1NGNA 3FSPA 4UNFA 1KG2A 2JPSA 4E7JA 1LWWA 1PU6A 3N5NX 4AI5A 3L2VA 2NOEA 3G0QA 3IH7A 3I0WA 2NOLA 1KG4A 3KTUA
chains in the Genus database with same CATH topology
3FHGA 2JG6A 1MUDA 1MUNA 1N3CA 4EVVA 1KG6A 3I0XA 4EJZA 2H56A 4YPRA 2JHNA 4PIIA 1KG3A 1M3QA 3OH6A 1VRLA 5CHZA 4AIAA 2NOZA 1PVSA 1EBMA 1NKUA 1ORPA 4HSBA 3CWUA 1RRSA 1N39A 1KG5A 3S6IA 3KNTA 1HU0A 1KG7A 4YOQA 3CW7A 1LWVA 4B23A 1FN7A 5KN9A 5DPKA 4E9EA 4UOBA 1XQPA 4B21A 1YQRA 3IHOA 3CWTA 1LMZA 2NOFA 1KQJA 4B22A 4E9FA 1LWYA 4YPHA 4OFHA 3OH9A 1YQLA 4AI4A 1WEGA 4OFEA 1P59A 2I5WA 1KO9A 1YQKA 2OFIA 1ORNA 4E9HA 4EJYA 1XQOA 2ABKA 3CVTA 1DIZA 1PU8A 4EA4A 1WEFA 2YG9A 1M3HA 2XHIA 3CWAA 2OFKA 1PU7A 3F10A 3CVSA 4EA5A 3D4VA 1N3AA 1WEIA 4EW4A 3N0UA 2NOIA 5AN4A 4EW0A 3OGDA 1KEAA 4B24A 2NOBA 1MUYA 4OFAA 2YG8A 3CWSA 3FHFA 2JHJA 1XG7A 1YQMA 5KN8A 4E9GA 4DK9A 2NOHA 1MPGA 1P7MA 1RRQA 3F0ZA 1NGNA 3FSPA 4UNFA 1KG2A 1LWWA 1PU6A 3N5NX 4AI5A 2NOEA 3G0QA 3IH7A 3I0WA 2NOLA 1KG4A 3KTUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FHG A;  2JG6 A;  1MUD A;  1MUN A;  1N3C A;  4EVV A;  1KG6 A;  3I0X A;  4EJZ A;  2H56 A;  4YPR A;  2JHN A;  4PII A;  1KG3 A;  1M3Q A;  3OH6 A;  1VRL A;  5CHZ A;  4AIA A;  2NOZ A;  1PVS A;  1EBM A;  1NKU A;  1ORP A;  4HSB A;  3CWU A;  1RRS A;  1N39 A;  1KG5 A;  3S6I A;  3KNT A;  1HU0 A;  1KG7 A;  4YOQ A;  3CW7 A;  1LWV A;  4B23 A;  1FN7 A;  5KN9 A;  5DPK A;  4E9E A;  4UOB A;  1XQP A;  4B21 A;  1YQR A;  3IHO A;  3CWT A;  1LMZ A;  2NOF A;  1KQJ A;  4B22 A;  4E9F A;  1LWY A;  4YPH A;  4OFH A;  3OH9 A;  1YQL A;  4AI4 A;  1WEG A;  4OFE A;  1P59 A;  2I5W A;  1KO9 A;  1YQK A;  2OFI A;  1ORN A;  4E9H A;  4EJY A;  1XQO A;  2ABK A;  3CVT A;  1DIZ A;  1PU8 A;  4EA4 A;  1WEF A;  2YG9 A;  1M3H A;  2XHI A;  3CWA A;  2OFK A;  1PU7 A;  3F10 A;  3CVS A;  4EA5 A;  3D4V A;  1N3A A;  1WEI A;  4EW4 A;  3N0U A;  2NOI A;  5AN4 A;  4EW0 A;  3OGD A;  1KEA A;  4B24 A;  2NOB A;  1MUY A;  4OFA A;  2YG8 A;  3CWS A;  3FHF A;  2JHJ A;  1XG7 A;  1YQM A;  5KN8 A;  4E9G A;  4DK9 A;  2NOH A;  1MPG A;  1P7M A;  1RRQ A;  3F0Z A;  1NGN A;  3FSP A;  4UNF A;  1KG2 A;  1LWW A;  1PU6 A;  3N5N X;  4AI5 A;  2NOE A;  3G0Q A;  3IH7 A;  3I0W A;  2NOL A;  1KG4 A;  3KTU A; 
#chains in the Genus database with same CATH topology
 3LCN A;  4E7K A;  3FHG A;  2JG6 A;  1MUD A;  1MUN A;  1N3C A;  4EVV A;  3S3O A;  3VW4 A;  3L2U A;  1KG6 A;  3OYL A;  3I0X A;  4BDY A;  4EJZ A;  3NNQ A;  2H56 A;  5FRO A;  4YPR A;  2JHN A;  4PII A;  1KG3 A;  1M3Q A;  3OH6 A;  1VRL A;  5CHZ A;  3OYA A;  3OYN A;  4BDZ A;  4AIA A;  2NOZ A;  1PVS A;  1EBM A;  4E7H A;  1NKU A;  1ORP A;  4HSB A;  3CWU A;  1RRS A;  3L2Q A;  4E7L A;  1KG5 A;  1N39 A;  3L2R A;  3S6I A;  3KNT A;  1HU0 A;  1KG7 A;  4YOQ A;  3CW7 A;  1LWV A;  4B23 A;  3OYD A;  5KN9 A;  5DPK A;  1FN7 A;  4E9E A;  2W04 A;  4UOB A;  1XQP A;  4B21 A;  3OYE A;  1YQR A;  3IHO A;  3OYJ A;  3CWT A;  1LMZ A;  2NOF A;  2V75 A;  1KQJ A;  3OS0 A;  4B22 A;  3OYF A;  3R2X C;  4E7I A;  3OYH A;  4E9F A;  3OYB A;  1LWY A;  4YPH A;  4BE0 A;  4OFH A;  3OH9 A;  1YQL A;  4AI4 A;  1WEG A;  4OFE A;  1P59 A;  2I5W A;  1KO9 A;  3OYK A;  1YQK A;  3OYM A;  2OFI A;  4BE2 A;  1ORN A;  4E9H A;  4EJY A;  1U84 A;  1XQO A;  2ABK A;  3CVT A;  1DIZ A;  1PU8 A;  4EA4 A;  3OS1 A;  1WEF A;  2YG9 A;  1M3H A;  2XHI A;  3CWA A;  3OYC A;  3OY9 A;  2OFK A;  1PU7 A;  3F10 A;  3CVS A;  4EA5 A;  4IKF A;  4BE1 A;  3D4V A;  2W03 A;  1N3A A;  4ZTJ A;  1WEI A;  4EW4 A;  4ZTF A;  3N0U A;  2NOI A;  5AN4 A;  4EW0 A;  3OGD A;  1KEA A;  4B24 A;  4BAC A;  2NOB A;  3OYI A;  5FRM A;  1MUY A;  4OFA A;  2YG8 A;  3CWS A;  3FHF A;  2JHJ A;  1XG7 A;  3L2W A;  1YQM A;  4NZG A;  5KN8 A;  3S3N A;  3S3M A;  5FRN A;  3OS2 A;  4E9G A;  4DK9 A;  2NOH A;  1MPG A;  1P7M A;  3OYG A;  1RRQ A;  3F0Z A;  1NGN A;  3FSP A;  4UNF A;  1KG2 A;  2JPS A;  4E7J A;  1LWW A;  1PU6 A;  3N5N X;  4AI5 A;  3L2V A;  2NOE A;  3G0Q A;  3IH7 A;  3I0W A;  2NOL A;  1KG4 A;  3KTU A; 
#chains in the Genus database with same CATH homology
 3FHG A;  2JG6 A;  1MUD A;  1MUN A;  1N3C A;  4EVV A;  1KG6 A;  3I0X A;  4EJZ A;  2H56 A;  4YPR A;  2JHN A;  4PII A;  1KG3 A;  1M3Q A;  3OH6 A;  1VRL A;  5CHZ A;  4AIA A;  2NOZ A;  1PVS A;  1EBM A;  1NKU A;  1ORP A;  4HSB A;  3CWU A;  1RRS A;  1N39 A;  1KG5 A;  3S6I A;  3KNT A;  1HU0 A;  1KG7 A;  4YOQ A;  3CW7 A;  1LWV A;  4B23 A;  1FN7 A;  5KN9 A;  5DPK A;  4E9E A;  4UOB A;  1XQP A;  4B21 A;  1YQR A;  3IHO A;  3CWT A;  1LMZ A;  2NOF A;  1KQJ A;  4B22 A;  4E9F A;  1LWY A;  4YPH A;  4OFH A;  3OH9 A;  1YQL A;  4AI4 A;  1WEG A;  4OFE A;  1P59 A;  2I5W A;  1KO9 A;  1YQK A;  2OFI A;  1ORN A;  4E9H A;  4EJY A;  1XQO A;  2ABK A;  3CVT A;  1DIZ A;  1PU8 A;  4EA4 A;  1WEF A;  2YG9 A;  1M3H A;  2XHI A;  3CWA A;  2OFK A;  1PU7 A;  3F10 A;  3CVS A;  4EA5 A;  3D4V A;  1N3A A;  1WEI A;  4EW4 A;  3N0U A;  2NOI A;  5AN4 A;  4EW0 A;  3OGD A;  1KEA A;  4B24 A;  2NOB A;  1MUY A;  4OFA A;  2YG8 A;  3CWS A;  3FHF A;  2JHJ A;  1XG7 A;  1YQM A;  5KN8 A;  4E9G A;  4DK9 A;  2NOH A;  1MPG A;  1P7M A;  1RRQ A;  3F0Z A;  1NGN A;  3FSP A;  4UNF A;  1KG2 A;  1LWW A;  1PU6 A;  3N5N X;  4AI5 A;  2NOE A;  3G0Q A;  3IH7 A;  3I0W A;  2NOL A;  1KG4 A;  3KTU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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