1KG4A

Crystal structure of the k142a mutant of e. coli muty (core fragment)
Total Genus 78
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
78
sequence length
224
structure length
224
Chain Sequence
MQASQFSAQVLDWYDKYGRKTLPWQIDKTPYKVWLSEVMLQQTQVATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGGKFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILDGNVARVLARCYAVSGWPGKKEVENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSKPKCSLCPLQNGCIAAANNSWALYPGKKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Analysis of the E.coli MutY DNA glycosylase structure and function by site-directed mutagenesis
rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords A/G-specific adenine glycosylase
total genus 78
structure length 224
sequence length 224
ec nomenclature ec 3.2.2.31: Adenine glycosylase.
pdb deposition date 2001-11-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00633 HHH Helix-hairpin-helix motif
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
A PF10576 EndIII_4Fe-2S Iron-sulfur binding domain of endonuclease III
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1kg4A02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1kg4A01
1MUDA 1PVSA 1ORPA 1HU0A 1KEAA 1M3QA 5KN9A 2JHJA 1KQJA 4YPRA 2NOZA 5KN8A 1KG4A 5DPKA 4B24A 1PU7A 4UNFA 3OH9A 3D4VA 2I5WA 3OGDA 1KG5A 4EA4A 1YQMA 1M3HA 3F0ZA 1ORNA 3N0UA 1P7MA 2ABKA 1NGNA 3CWUA 4YPHA 1N3CA 2NOHA 1LWWA 1VRLA 1MUYA 2NOBA 4E9HA 4OFAA 1XQPA 3OH6A 1KG2A 1WEGA 1WEIA 1KG3A 2YG9A 1DIZA 4EA5A 1PU8A 2H56A 3FSPA 1KG6A 4AI5A 1YQLA 2OFIA 4EJYA 4AIAA 4PIIA 5CHZA 1N39A 3FHGA 4DK9A 1XG7A 3IHOA 4OFHA 2NOEA 3FHFA 1MUNA 1KG7A 1P59A 1N3AA 3KNTA 4EVVA 3CW7A 2NOFA 1LWVA 4B21A 1WEFA 3CVTA 2NOIA 1RRSA 1LWYA 1YQRA 2JG6A 3F10A 3CWTA 2YG8A 4AI4A 3I0XA 2OFKA 3KTUA 1NKUA 2NOLA 1RRQA 4UOBA 4E9EA 3CVSA 4E9GA 4EW0A 3CWSA 1KO9A 4B23A 4OFEA 3I0WA 1XQOA 1YQKA 3CWAA 1EBMA 5AN4A 3G0QA 3N5NX 4B22A 1FN7A 4EJZA 4YOQA 3S6IA 4HSBA 4EW4A 3IH7A 2XHIA 4E9FA 1PU6A 1MPGA 2JHNA 1LMZA
chains in the Genus database with same CATH superfamily
3OYCA 1MUDA 1PVSA 1ORPA 1HU0A 1KEAA 1M3QA 5KN9A 2JHJA 4ZTJA 1KQJA 4YPRA 4BDZA 2NOZA 5KN8A 4E7HA 1KG4A 5DPKA 4B24A 1PU7A 3OYEA 4UNFA 3OH9A 3D4VA 2V75A 2I5WA 3OGDA 1U84A 3LCNA 1KG5A 4EA4A 1YQMA 3OYIA 1M3HA 3F0ZA 1ORNA 3N0UA 1P7MA 4ZTFA 2ABKA 3OS0A 3OYLA 1NGNA 3CWUA 4YPHA 1N3CA 2NOHA 1LWWA 3R2XC 3S3OA 1VRLA 1MUYA 2NOBA 3OS1A 3OYMA 4E9HA 4OFAA 1XQPA 3OH6A 1KG2A 3OYFA 4E7KA 1WEGA 1WEIA 3L2UA 1KG3A 2YG9A 3OYGA 3S3MA 1DIZA 2W04A 4E7JA 5FRMA 4EA5A 1PU8A 2H56A 3FSPA 1KG6A 4AI5A 5FROA 1YQLA 2OFIA 4EJYA 4AIAA 4PIIA 5CHZA 1N39A 3FHGA 3OYBA 4BE2A 4DK9A 1XG7A 3IHOA 4OFHA 3NNQA 4E7IA 2NOEA 3FHFA 1MUNA 1KG7A 1P59A 1N3AA 3OYHA 3KNTA 4BE1A 3S3NA 4EVVA 5FRNA 3CW7A 2NOFA 1LWVA 4B21A 1WEFA 4BACA 3CVTA 2NOIA 3OS2A 1RRSA 1LWYA 1YQRA 2W03A 3L2RA 4IKFA 2JG6A 3F10A 3CWTA 2YG8A 4AI4A 3OYKA 3I0XA 2OFKA 3KTUA 3L2WA 1NKUA 2NOLA 3OYNA 1RRQA 4UOBA 4BDYA 4E9EA 3CVSA 4E9GA 4EW0A 3CWSA 1KO9A 4BE0A 4B23A 4OFEA 3I0WA 3VW4A 1XQOA 4NZGA 4E7LA 1YQKA 2JPSA 3OYAA 3CWAA 3L2VA 1EBMA 3OY9A 5AN4A 3G0QA 3N5NX 4B22A 1FN7A 4EJZA 4YOQA 3OYJA 3S6IA 4HSBA 4EW4A 3IH7A 3L2QA 2XHIA 4E9FA 3OYDA 1PU6A 1MPGA 2JHNA 1LMZA
chains in the Genus database with same CATH topology
1MUDA 1PVSA 1ORPA 1HU0A 1KEAA 1M3QA 5KN9A 2JHJA 1KQJA 4YPRA 2NOZA 5KN8A 1KG4A 5DPKA 4B24A 1PU7A 4UNFA 3OH9A 3D4VA 2I5WA 3OGDA 1KG5A 4EA4A 1YQMA 1M3HA 3F0ZA 1ORNA 3N0UA 1P7MA 2ABKA 1NGNA 3CWUA 4YPHA 1N3CA 2NOHA 1LWWA 1VRLA 1MUYA 2NOBA 4E9HA 4OFAA 1XQPA 3OH6A 1KG2A 1WEGA 1WEIA 1KG3A 2YG9A 1DIZA 4EA5A 1PU8A 2H56A 3FSPA 1KG6A 4AI5A 1YQLA 2OFIA 4EJYA 4AIAA 4PIIA 5CHZA 1N39A 3FHGA 4DK9A 1XG7A 3IHOA 4OFHA 2NOEA 3FHFA 1MUNA 1KG7A 1P59A 1N3AA 3KNTA 4EVVA 3CW7A 2NOFA 1LWVA 4B21A 1WEFA 3CVTA 2NOIA 1RRSA 1LWYA 1YQRA 2JG6A 3F10A 3CWTA 2YG8A 4AI4A 3I0XA 2OFKA 3KTUA 1NKUA 2NOLA 1RRQA 4UOBA 4E9EA 3CVSA 4E9GA 4EW0A 3CWSA 1KO9A 4B23A 4OFEA 3I0WA 1XQOA 1YQKA 3CWAA 1EBMA 5AN4A 3G0QA 3N5NX 4B22A 1FN7A 4EJZA 4YOQA 3S6IA 4HSBA 4EW4A 3IH7A 2XHIA 4E9FA 1PU6A 1MPGA 2JHNA 1LMZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1MUD A;  1PVS A;  1ORP A;  1HU0 A;  1KEA A;  1M3Q A;  5KN9 A;  2JHJ A;  1KQJ A;  4YPR A;  2NOZ A;  5KN8 A;  1KG4 A;  5DPK A;  4B24 A;  1PU7 A;  4UNF A;  3OH9 A;  3D4V A;  2I5W A;  3OGD A;  1KG5 A;  4EA4 A;  1YQM A;  1M3H A;  3F0Z A;  1ORN A;  3N0U A;  1P7M A;  2ABK A;  1NGN A;  3CWU A;  4YPH A;  1N3C A;  2NOH A;  1LWW A;  1VRL A;  1MUY A;  2NOB A;  4E9H A;  4OFA A;  1XQP A;  3OH6 A;  1KG2 A;  1WEG A;  1WEI A;  1KG3 A;  2YG9 A;  1DIZ A;  4EA5 A;  1PU8 A;  2H56 A;  3FSP A;  1KG6 A;  4AI5 A;  1YQL A;  2OFI A;  4EJY A;  4AIA A;  4PII A;  5CHZ A;  1N39 A;  3FHG A;  4DK9 A;  1XG7 A;  3IHO A;  4OFH A;  2NOE A;  3FHF A;  1MUN A;  1KG7 A;  1P59 A;  1N3A A;  3KNT A;  4EVV A;  3CW7 A;  2NOF A;  1LWV A;  4B21 A;  1WEF A;  3CVT A;  2NOI A;  1RRS A;  1LWY A;  1YQR A;  2JG6 A;  3F10 A;  3CWT A;  2YG8 A;  4AI4 A;  3I0X A;  2OFK A;  3KTU A;  1NKU A;  2NOL A;  1RRQ A;  4UOB A;  4E9E A;  3CVS A;  4E9G A;  4EW0 A;  3CWS A;  1KO9 A;  4B23 A;  4OFE A;  3I0W A;  1XQO A;  1YQK A;  3CWA A;  1EBM A;  5AN4 A;  3G0Q A;  3N5N X;  4B22 A;  1FN7 A;  4EJZ A;  4YOQ A;  3S6I A;  4HSB A;  4EW4 A;  3IH7 A;  2XHI A;  4E9F A;  1PU6 A;  1MPG A;  2JHN A;  1LMZ A; 
#chains in the Genus database with same CATH topology
 3OYC A;  1MUD A;  1PVS A;  1ORP A;  1HU0 A;  1KEA A;  1M3Q A;  5KN9 A;  2JHJ A;  4ZTJ A;  1KQJ A;  4YPR A;  4BDZ A;  2NOZ A;  5KN8 A;  4E7H A;  1KG4 A;  5DPK A;  4B24 A;  1PU7 A;  3OYE A;  4UNF A;  3OH9 A;  3D4V A;  2V75 A;  2I5W A;  3OGD A;  1U84 A;  3LCN A;  1KG5 A;  4EA4 A;  1YQM A;  3OYI A;  1M3H A;  3F0Z A;  1ORN A;  3N0U A;  1P7M A;  4ZTF A;  2ABK A;  3OS0 A;  3OYL A;  1NGN A;  3CWU A;  4YPH A;  1N3C A;  2NOH A;  1LWW A;  3R2X C;  3S3O A;  1VRL A;  1MUY A;  2NOB A;  3OS1 A;  3OYM A;  4E9H A;  4OFA A;  1XQP A;  3OH6 A;  1KG2 A;  3OYF A;  4E7K A;  1WEG A;  1WEI A;  3L2U A;  1KG3 A;  2YG9 A;  3OYG A;  3S3M A;  1DIZ A;  2W04 A;  4E7J A;  5FRM A;  4EA5 A;  1PU8 A;  2H56 A;  3FSP A;  1KG6 A;  4AI5 A;  5FRO A;  1YQL A;  2OFI A;  4EJY A;  4AIA A;  4PII A;  5CHZ A;  1N39 A;  3FHG A;  3OYB A;  4BE2 A;  4DK9 A;  1XG7 A;  3IHO A;  4OFH A;  3NNQ A;  4E7I A;  2NOE A;  3FHF A;  1MUN A;  1KG7 A;  1P59 A;  1N3A A;  3OYH A;  3KNT A;  4BE1 A;  3S3N A;  4EVV A;  5FRN A;  3CW7 A;  2NOF A;  1LWV A;  4B21 A;  1WEF A;  4BAC A;  3CVT A;  2NOI A;  3OS2 A;  1RRS A;  1LWY A;  1YQR A;  2W03 A;  3L2R A;  4IKF A;  2JG6 A;  3F10 A;  3CWT A;  2YG8 A;  4AI4 A;  3OYK A;  3I0X A;  2OFK A;  3KTU A;  3L2W A;  1NKU A;  2NOL A;  3OYN A;  1RRQ A;  4UOB A;  4BDY A;  4E9E A;  3CVS A;  4E9G A;  4EW0 A;  3CWS A;  1KO9 A;  4BE0 A;  4B23 A;  4OFE A;  3I0W A;  3VW4 A;  1XQO A;  4NZG A;  4E7L A;  1YQK A;  2JPS A;  3OYA A;  3CWA A;  3L2V A;  1EBM A;  3OY9 A;  5AN4 A;  3G0Q A;  3N5N X;  4B22 A;  1FN7 A;  4EJZ A;  4YOQ A;  3OYJ A;  3S6I A;  4HSB A;  4EW4 A;  3IH7 A;  3L2Q A;  2XHI A;  4E9F A;  3OYD A;  1PU6 A;  1MPG A;  2JHN A;  1LMZ A; 
#chains in the Genus database with same CATH homology
 1MUD A;  1PVS A;  1ORP A;  1HU0 A;  1KEA A;  1M3Q A;  5KN9 A;  2JHJ A;  1KQJ A;  4YPR A;  2NOZ A;  5KN8 A;  1KG4 A;  5DPK A;  4B24 A;  1PU7 A;  4UNF A;  3OH9 A;  3D4V A;  2I5W A;  3OGD A;  1KG5 A;  4EA4 A;  1YQM A;  1M3H A;  3F0Z A;  1ORN A;  3N0U A;  1P7M A;  2ABK A;  1NGN A;  3CWU A;  4YPH A;  1N3C A;  2NOH A;  1LWW A;  1VRL A;  1MUY A;  2NOB A;  4E9H A;  4OFA A;  1XQP A;  3OH6 A;  1KG2 A;  1WEG A;  1WEI A;  1KG3 A;  2YG9 A;  1DIZ A;  4EA5 A;  1PU8 A;  2H56 A;  3FSP A;  1KG6 A;  4AI5 A;  1YQL A;  2OFI A;  4EJY A;  4AIA A;  4PII A;  5CHZ A;  1N39 A;  3FHG A;  4DK9 A;  1XG7 A;  3IHO A;  4OFH A;  2NOE A;  3FHF A;  1MUN A;  1KG7 A;  1P59 A;  1N3A A;  3KNT A;  4EVV A;  3CW7 A;  2NOF A;  1LWV A;  4B21 A;  1WEF A;  3CVT A;  2NOI A;  1RRS A;  1LWY A;  1YQR A;  2JG6 A;  3F10 A;  3CWT A;  2YG8 A;  4AI4 A;  3I0X A;  2OFK A;  3KTU A;  1NKU A;  2NOL A;  1RRQ A;  4UOB A;  4E9E A;  3CVS A;  4E9G A;  4EW0 A;  3CWS A;  1KO9 A;  4B23 A;  4OFE A;  3I0W A;  1XQO A;  1YQK A;  3CWA A;  1EBM A;  5AN4 A;  3G0Q A;  3N5N X;  4B22 A;  1FN7 A;  4EJZ A;  4YOQ A;  3S6I A;  4HSB A;  4EW4 A;  3IH7 A;  2XHI A;  4E9F A;  1PU6 A;  1MPG A;  2JHN A;  1LMZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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