1KG4A

Crystal structure of the k142a mutant of e. coli muty (core fragment)
Total Genus 78
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
78
sequence length
224
structure length
224
Chain Sequence
MQASQFSAQVLDWYDKYGRKTLPWQIDKTPYKVWLSEVMLQQTQVATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGGKFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILDGNVARVLARCYAVSGWPGKKEVENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSKPKCSLCPLQNGCIAAANNSWALYPGKKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords A/G-specific adenine glycosylase
publication title Analysis of the E.coli MutY DNA glycosylase structure and function by site-directed mutagenesis
rcsb
source organism Escherichia coli
molecule tags Hydrolase
total genus 78
structure length 224
sequence length 224
ec nomenclature ec 3.2.2.31: Adenine glycosylase.
pdb deposition date 2001-11-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00633 HHH Helix-hairpin-helix motif
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
A PF10576 EndIII_4Fe-2S Iron-sulfur binding domain of endonuclease III
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1kg4A02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1kg4A01
2NOZA 1PVSA 1LMZA 1KQJA 4B24A 2NOLA 4OFEA 3CWUA 3FSPA 1NGNA 5KN8A 1LWYA 3OH9A 1KG7A 4B23A 2NOHA 1P59A 1XG7A 4AIAA 1XQOA 1MUYA 4YPHA 3CW7A 4UNFA 4EJZA 4E9FA 4AI5A 2I5WA 1YQKA 4EA4A 2NOIA 3N5NX 1KG2A 3OH6A 3F0ZA 3KTUA 1YQLA 2YG8A 4UOBA 1NKUA 5CHZA 1RRQA 3N0UA 3OGDA 1RRSA 2H56A 4HSBA 1YQMA 3CWTA 3KNTA 1N3AA 2NOEA 4YOQA 4EJYA 4PIIA 4E9GA 4EW0A 1MPGA 3F10A 1ORPA 2NOBA 1EBMA 3IH7A 3CWAA 1KG3A 1KG5A 3D4VA 5DPKA 2XHIA 4B21A 1LWVA 4E9EA 1DIZA 1M3QA 4OFAA 4OFHA 3G0QA 4EVVA 4EW4A 1ORNA 4E9HA 1WEFA 1YQRA 1LWWA 1P7MA 2YG9A 1KEAA 1MUDA 1PU8A 1WEIA 2NOFA 1PU7A 1WEGA 3CWSA 1HU0A 1FN7A 2JHNA 3CVSA 4AI4A 4B22A 3FHFA 2ABKA 3FHGA 3CVTA 1XQPA 3IHOA 1KG4A 3I0WA 3S6IA 2JG6A 4EA5A 3I0XA 1VRLA 2JHJA 1N39A 1KO9A 1PU6A 1M3HA 5KN9A 2OFKA 1KG6A 4DK9A 1MUNA 1N3CA 4YPRA 2OFIA 5AN4A
chains in the Genus database with same CATH superfamily
2NOZA 1PVSA 1LMZA 1KQJA 4B24A 2NOLA 3OS0A 4OFEA 3CWUA 3FSPA 1NGNA 4BE2A 5KN8A 3OYGA 1LWYA 3OYBA 3OH9A 1KG7A 3S3OA 4B23A 2NOHA 1P59A 1XG7A 3L2VA 4AIAA 1XQOA 1MUYA 4YPHA 3CW7A 4UNFA 3LCNA 4EJZA 4E9FA 4AI5A 2I5WA 1YQKA 4EA4A 4E7LA 2NOIA 4BDZA 3N5NX 3OY9A 1KG2A 3VW4A 3OH6A 4ZTFA 3F0ZA 5FRMA 3KTUA 4E7JA 1YQLA 3OYCA 3OYMA 3L2WA 2YG8A 4E7KA 4UOBA 1NKUA 5CHZA 3OYHA 3N0UA 3OGDA 3L2RA 1RRQA 1RRSA 2H56A 4HSBA 3OYNA 1YQMA 3CWTA 3KNTA 1N3AA 2NOEA 4YOQA 4EJYA 4ZTJA 4PIIA 2W04A 3OYAA 4E9GA 4EW0A 1MPGA 3F10A 1ORPA 2NOBA 1EBMA 3IH7A 3CWAA 4BE0A 3NNQA 1KG3A 1KG5A 3OYDA 3D4VA 3OS1A 5DPKA 3OYEA 2XHIA 4BE1A 4B21A 1LWVA 4E9EA 3OYKA 1DIZA 3L2UA 1M3QA 3OYJA 4OFAA 4OFHA 3G0QA 4EVVA 4EW4A 1ORNA 4E9HA 1WEFA 3OS2A 1YQRA 1LWWA 1P7MA 2YG9A 1KEAA 1MUDA 1PU8A 1WEIA 4BACA 2NOFA 1U84A 3R2XC 1PU7A 1WEGA 3CWSA 1HU0A 4E7IA 1FN7A 3S3NA 2JHNA 3L2QA 3OYFA 3CVSA 2JPSA 4AI4A 4B22A 3FHFA 2ABKA 2OFIA 3OYLA 3FHGA 3CVTA 1XQPA 4E7HA 5FROA 3IHOA 1KG4A 3I0WA 3S6IA 2JG6A 4EA5A 3I0XA 3OYIA 1VRLA 2JHJA 1N39A 1KO9A 3S3MA 1PU6A 4IKFA 1M3HA 5KN9A 2OFKA 2W03A 1KG6A 4DK9A 5FRNA 4NZGA 1MUNA 1N3CA 4YPRA 2V75A 4BDYA 5AN4A
chains in the Genus database with same CATH topology
2NOZA 1PVSA 1LMZA 1KQJA 4B24A 2NOLA 4OFEA 3CWUA 3FSPA 1NGNA 5KN8A 1LWYA 3OH9A 1KG7A 4B23A 2NOHA 1P59A 1XG7A 4AIAA 1XQOA 1MUYA 4YPHA 3CW7A 4UNFA 4EJZA 4E9FA 4AI5A 2I5WA 1YQKA 4EA4A 2NOIA 3N5NX 1KG2A 3OH6A 3F0ZA 3KTUA 1YQLA 2YG8A 4UOBA 1NKUA 5CHZA 1RRQA 3N0UA 3OGDA 1RRSA 2H56A 4HSBA 1YQMA 3CWTA 3KNTA 1N3AA 2NOEA 4YOQA 4EJYA 4PIIA 4E9GA 4EW0A 1MPGA 3F10A 1ORPA 2NOBA 1EBMA 3IH7A 3CWAA 1KG3A 1KG5A 3D4VA 5DPKA 2XHIA 4B21A 1LWVA 4E9EA 1DIZA 1M3QA 4OFAA 4OFHA 3G0QA 4EVVA 4EW4A 1ORNA 4E9HA 1WEFA 1YQRA 1LWWA 1P7MA 2YG9A 1KEAA 1MUDA 1PU8A 1WEIA 2NOFA 1PU7A 1WEGA 3CWSA 1HU0A 1FN7A 2JHNA 3CVSA 4AI4A 4B22A 3FHFA 2ABKA 3FHGA 3CVTA 1XQPA 3IHOA 1KG4A 3I0WA 3S6IA 2JG6A 4EA5A 3I0XA 1VRLA 2JHJA 1N39A 1KO9A 1PU6A 1M3HA 5KN9A 2OFKA 1KG6A 4DK9A 1MUNA 1N3CA 4YPRA 2OFIA 5AN4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NOZ A;  1PVS A;  1LMZ A;  1KQJ A;  4B24 A;  2NOL A;  4OFE A;  3CWU A;  3FSP A;  1NGN A;  5KN8 A;  1LWY A;  3OH9 A;  1KG7 A;  4B23 A;  2NOH A;  1P59 A;  1XG7 A;  4AIA A;  1XQO A;  1MUY A;  4YPH A;  3CW7 A;  4UNF A;  4EJZ A;  4E9F A;  4AI5 A;  2I5W A;  1YQK A;  4EA4 A;  2NOI A;  3N5N X;  1KG2 A;  3OH6 A;  3F0Z A;  3KTU A;  1YQL A;  2YG8 A;  4UOB A;  1NKU A;  5CHZ A;  1RRQ A;  3N0U A;  3OGD A;  1RRS A;  2H56 A;  4HSB A;  1YQM A;  3CWT A;  3KNT A;  1N3A A;  2NOE A;  4YOQ A;  4EJY A;  4PII A;  4E9G A;  4EW0 A;  1MPG A;  3F10 A;  1ORP A;  2NOB A;  1EBM A;  3IH7 A;  3CWA A;  1KG3 A;  1KG5 A;  3D4V A;  5DPK A;  2XHI A;  4B21 A;  1LWV A;  4E9E A;  1DIZ A;  1M3Q A;  4OFA A;  4OFH A;  3G0Q A;  4EVV A;  4EW4 A;  1ORN A;  4E9H A;  1WEF A;  1YQR A;  1LWW A;  1P7M A;  2YG9 A;  1KEA A;  1MUD A;  1PU8 A;  1WEI A;  2NOF A;  1PU7 A;  1WEG A;  3CWS A;  1HU0 A;  1FN7 A;  2JHN A;  3CVS A;  4AI4 A;  4B22 A;  3FHF A;  2ABK A;  3FHG A;  3CVT A;  1XQP A;  3IHO A;  1KG4 A;  3I0W A;  3S6I A;  2JG6 A;  4EA5 A;  3I0X A;  1VRL A;  2JHJ A;  1N39 A;  1KO9 A;  1PU6 A;  1M3H A;  5KN9 A;  2OFK A;  1KG6 A;  4DK9 A;  1MUN A;  1N3C A;  4YPR A;  2OFI A;  5AN4 A; 
#chains in the Genus database with same CATH topology
 2NOZ A;  1PVS A;  1LMZ A;  1KQJ A;  4B24 A;  2NOL A;  3OS0 A;  4OFE A;  3CWU A;  3FSP A;  1NGN A;  4BE2 A;  5KN8 A;  3OYG A;  1LWY A;  3OYB A;  3OH9 A;  1KG7 A;  3S3O A;  4B23 A;  2NOH A;  1P59 A;  1XG7 A;  3L2V A;  4AIA A;  1XQO A;  1MUY A;  4YPH A;  3CW7 A;  4UNF A;  3LCN A;  4EJZ A;  4E9F A;  4AI5 A;  2I5W A;  1YQK A;  4EA4 A;  4E7L A;  2NOI A;  4BDZ A;  3N5N X;  3OY9 A;  1KG2 A;  3VW4 A;  3OH6 A;  4ZTF A;  3F0Z A;  5FRM A;  3KTU A;  4E7J A;  1YQL A;  3OYC A;  3OYM A;  3L2W A;  2YG8 A;  4E7K A;  4UOB A;  1NKU A;  5CHZ A;  3OYH A;  3N0U A;  3OGD A;  3L2R A;  1RRQ A;  1RRS A;  2H56 A;  4HSB A;  3OYN A;  1YQM A;  3CWT A;  3KNT A;  1N3A A;  2NOE A;  4YOQ A;  4EJY A;  4ZTJ A;  4PII A;  2W04 A;  3OYA A;  4E9G A;  4EW0 A;  1MPG A;  3F10 A;  1ORP A;  2NOB A;  1EBM A;  3IH7 A;  3CWA A;  4BE0 A;  3NNQ A;  1KG3 A;  1KG5 A;  3OYD A;  3D4V A;  3OS1 A;  5DPK A;  3OYE A;  2XHI A;  4BE1 A;  4B21 A;  1LWV A;  4E9E A;  3OYK A;  1DIZ A;  3L2U A;  1M3Q A;  3OYJ A;  4OFA A;  4OFH A;  3G0Q A;  4EVV A;  4EW4 A;  1ORN A;  4E9H A;  1WEF A;  3OS2 A;  1YQR A;  1LWW A;  1P7M A;  2YG9 A;  1KEA A;  1MUD A;  1PU8 A;  1WEI A;  4BAC A;  2NOF A;  1U84 A;  3R2X C;  1PU7 A;  1WEG A;  3CWS A;  1HU0 A;  4E7I A;  1FN7 A;  3S3N A;  2JHN A;  3L2Q A;  3OYF A;  3CVS A;  2JPS A;  4AI4 A;  4B22 A;  3FHF A;  2ABK A;  2OFI A;  3OYL A;  3FHG A;  3CVT A;  1XQP A;  4E7H A;  5FRO A;  3IHO A;  1KG4 A;  3I0W A;  3S6I A;  2JG6 A;  4EA5 A;  3I0X A;  3OYI A;  1VRL A;  2JHJ A;  1N39 A;  1KO9 A;  3S3M A;  1PU6 A;  4IKF A;  1M3H A;  5KN9 A;  2OFK A;  2W03 A;  1KG6 A;  4DK9 A;  5FRN A;  4NZG A;  1MUN A;  1N3C A;  4YPR A;  2V75 A;  4BDY A;  5AN4 A; 
#chains in the Genus database with same CATH homology
 2NOZ A;  1PVS A;  1LMZ A;  1KQJ A;  4B24 A;  2NOL A;  4OFE A;  3CWU A;  3FSP A;  1NGN A;  5KN8 A;  1LWY A;  3OH9 A;  1KG7 A;  4B23 A;  2NOH A;  1P59 A;  1XG7 A;  4AIA A;  1XQO A;  1MUY A;  4YPH A;  3CW7 A;  4UNF A;  4EJZ A;  4E9F A;  4AI5 A;  2I5W A;  1YQK A;  4EA4 A;  2NOI A;  3N5N X;  1KG2 A;  3OH6 A;  3F0Z A;  3KTU A;  1YQL A;  2YG8 A;  4UOB A;  1NKU A;  5CHZ A;  1RRQ A;  3N0U A;  3OGD A;  1RRS A;  2H56 A;  4HSB A;  1YQM A;  3CWT A;  3KNT A;  1N3A A;  2NOE A;  4YOQ A;  4EJY A;  4PII A;  4E9G A;  4EW0 A;  1MPG A;  3F10 A;  1ORP A;  2NOB A;  1EBM A;  3IH7 A;  3CWA A;  1KG3 A;  1KG5 A;  3D4V A;  5DPK A;  2XHI A;  4B21 A;  1LWV A;  4E9E A;  1DIZ A;  1M3Q A;  4OFA A;  4OFH A;  3G0Q A;  4EVV A;  4EW4 A;  1ORN A;  4E9H A;  1WEF A;  1YQR A;  1LWW A;  1P7M A;  2YG9 A;  1KEA A;  1MUD A;  1PU8 A;  1WEI A;  2NOF A;  1PU7 A;  1WEG A;  3CWS A;  1HU0 A;  1FN7 A;  2JHN A;  3CVS A;  4AI4 A;  4B22 A;  3FHF A;  2ABK A;  3FHG A;  3CVT A;  1XQP A;  3IHO A;  1KG4 A;  3I0W A;  3S6I A;  2JG6 A;  4EA5 A;  3I0X A;  1VRL A;  2JHJ A;  1N39 A;  1KO9 A;  1PU6 A;  1M3H A;  5KN9 A;  2OFK A;  1KG6 A;  4DK9 A;  1MUN A;  1N3C A;  4YPR A;  2OFI A;  5AN4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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