1KHOA

Crystal structure analysis of clostridium perfringens alpha-toxin isolated from avian strain swcp
Total Genus 141
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
141
sequence length
370
structure length
370
Chain Sequence
WDGKADGTGTHAMIATQGVTILENDLSSNEPEVIRNNLEILKQNMHDLQLGSTYPDYDKNAYDLYQDHFWDPDTDNNFTKDSKWYLSYSIPDTAESQIRKFSALARYEWKRGNYKQATFYLGEAMHYFGDADTPYHAANVTAVDSPGHVKFETFAEDRKDQYKINTTGSKTNDAFYSNILTNEDFNSWSKEFARSFAKTAKDLYYSHANMSCSWDEWDYAAKVALANSQKGTSGYIYRFLHDVSDGKDSSANKNVNELVAYITTGGEKYAGTDDYMYFGIKTKDGQTQEWTMDNPGNDFMTGSQDTYTFKLKDKNLKIDDIQNMWIRKSKYTEFGDDYKPANIKVIANGNVVLNKDINEWISGNSTYNIK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The first strain of Clostridium perfringens isolated from an avian source has an alpha-toxin with divergent structural and kinetic properties.
pubmed doi rcsb
molecule tags Toxin
source organism Clostridium perfringens
molecule keywords alpha-toxin
total genus 141
structure length 370
sequence length 370
chains with identical sequence B
ec nomenclature ec 3.1.4.3: Phospholipase C.
pdb deposition date 2001-11-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00882 Zn_dep_PLPC Zinc dependent phospholipase C
A PF01477 PLAT PLAT/LH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.575.10 Mainly Alpha Orthogonal Bundle P1 Nuclease P1 Nuclease 1khoA01
2.60.60.20 Mainly Beta Sandwich Lipoxygenase-1 PLAT/LH2 domain 1khoA02
2WXUA 5FBGA 1GPLA 2FGNA 1NO3A 3BNDA 2PPLA 1FGTA 3V98A 1P6DA 2FNQA 4WHAA 1QMDA 1LPBB 5FBCA 4CXPA 1LPAB 1RP1A 3PZWA 5FBBA 3O8YA 3V99A 5FBDA 3FG4A 1IK3A 2WY6A 1YGEA 1AH7A 1KHOA 1FGQA 4CXOA 1LNHA 1QM6A 1HU9A 5FBAA 3BNEA 2WXTA 4CXVA 1BU8A 4WFOA 3FG1A 1F8NA 2P0MA 1OLPA 1FGRA 3V92A 2FFZA 1N8SA 5FBFA 1RRHA 3CWZB 2IUKA 1FGOA 5EEOA 2SBLA 1CA1A 1Y4KA 1AK0A 1RRLA 1W52X 1ETHA 4DJ4A 3W52A 2OXEA 1JNQA 3BNBA 1P6EA 3SNGA 2IUJA 1HPLA 4QWTA 4NREA 1FGMA 2PVSA 1GYGA 5FB9A 4CWMA 3VF1A 2HUCA 1LOXA 1P5XA 1N8QA 3FG3A 1ROVA 3BNCA 4JDGA
chains in the Genus database with same CATH superfamily
2WXUA 5FBGA 1GPLA 2FGNA 1NO3A 3BNDA 4QEYA 2PPLA 1FGTA 3V98A 1P6DA 2FNQA 4WHAA 1QMDA 1LPBB 5FBCA 4CXPA 1LPAB 1RP1A 3PZWA 5FBBA 3O8YA 3V99A 5FBDA 3FG4A 1IK3A 2WY6A 1YGEA 1AH7A 1KHOA 1FGQA 4CXOA 1LNHA 1QM6A 1HU9A 2QZ7A 5FBAA 3BNEA 2WXTA 4CXVA 1BU8A 4WFOA 3FG1A 1F8NA 2P0MA 2XFEA 1OLPA 2XHHA 1FGRA 3V92A 2FFZA 1N8SA 5FBFA 1RRHA 2LRGA 3CWZB 3IBZA 2IUKA 1FGOA 5EEOA 2SBLA 1CA1A 2QNGA 1Y4KA 1AK0A 1RRLA 1W52X 1ETHA 4DJ4A 3W52A 2LG7A 2OXEA 1JNQA 3BNBA 1P6EA 3SNGA 2IUJA 2LGEA 1HPLA 2KXVA 4NREA 4QWTA 1FGMA 2PVSA 1GYGA 2XFDA 2XHJA 5FB9A 4CWMA 2KXTA 3VF1A 2HUCA 1LOXA 1P5XA 1N8QA 3FG3A 1ROVA 3BNCA 3U6GA 4JDGA
chains in the Genus database with same CATH topology
2WXUA 5FBGA 1GPLA 2FGNA 1NO3A 3BNDA 2PPLA 1FGTA 3V98A 1P6DA 2FNQA 4WHAA 1QMDA 1LPBB 5FBCA 4CXPA 1LPAB 1RP1A 3PZWA 5FBBA 3O8YA 3V99A 5FBDA 3FG4A 1IK3A 2WY6A 1YGEA 1AH7A 1KHOA 1FGQA 4CXOA 1LNHA 1QM6A 1HU9A 5FBAA 3BNEA 2WXTA 4CXVA 1BU8A 4WFOA 3FG1A 1F8NA 2P0MA 1OLPA 1FGRA 3V92A 2FFZA 1N8SA 5FBFA 1RRHA 3CWZB 2IUKA 1FGOA 5EEOA 2SBLA 1CA1A 1Y4KA 1AK0A 1RRLA 1W52X 1ETHA 4DJ4A 3W52A 2OXEA 1JNQA 3BNBA 1P6EA 3SNGA 2IUJA 1HPLA 4QWTA 4NREA 1FGMA 2PVSA 1GYGA 5FB9A 4CWMA 3VF1A 2HUCA 1LOXA 1P5XA 1N8QA 3FG3A 1ROVA 3BNCA 4JDGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WXU A;  5FBG A;  1GPL A;  2FGN A;  1NO3 A;  3BND A;  2PPL A;  1FGT A;  3V98 A;  1P6D A;  2FNQ A;  4WHA A;  1QMD A;  1LPB B;  5FBC A;  4CXP A;  1LPA B;  1RP1 A;  3PZW A;  5FBB A;  3O8Y A;  3V99 A;  5FBD A;  3FG4 A;  1IK3 A;  2WY6 A;  1YGE A;  1AH7 A;  1KHO A;  1FGQ A;  4CXO A;  1LNH A;  1QM6 A;  1HU9 A;  5FBA A;  3BNE A;  2WXT A;  4CXV A;  1BU8 A;  4WFO A;  3FG1 A;  1F8N A;  2P0M A;  1OLP A;  1FGR A;  3V92 A;  2FFZ A;  1N8S A;  5FBF A;  1RRH A;  3CWZ B;  2IUK A;  1FGO A;  5EEO A;  2SBL A;  1CA1 A;  1Y4K A;  1AK0 A;  1RRL A;  1W52 X;  1ETH A;  4DJ4 A;  3W52 A;  2OXE A;  1JNQ A;  3BNB A;  1P6E A;  3SNG A;  2IUJ A;  1HPL A;  4QWT A;  4NRE A;  1FGM A;  2PVS A;  1GYG A;  5FB9 A;  4CWM A;  3VF1 A;  2HUC A;  1LOX A;  1P5X A;  1N8Q A;  3FG3 A;  1ROV A;  3BNC A;  4JDG A; 
#chains in the Genus database with same CATH topology
 2WXU A;  5FBG A;  1GPL A;  2FGN A;  1NO3 A;  3BND A;  4QEY A;  2PPL A;  1FGT A;  3V98 A;  1P6D A;  2FNQ A;  4WHA A;  1QMD A;  1LPB B;  5FBC A;  4CXP A;  1LPA B;  1RP1 A;  3PZW A;  5FBB A;  3O8Y A;  3V99 A;  5FBD A;  3FG4 A;  1IK3 A;  2WY6 A;  1YGE A;  1AH7 A;  1KHO A;  1FGQ A;  4CXO A;  1LNH A;  1QM6 A;  1HU9 A;  2QZ7 A;  5FBA A;  3BNE A;  2WXT A;  4CXV A;  1BU8 A;  4WFO A;  3FG1 A;  1F8N A;  2P0M A;  2XFE A;  1OLP A;  2XHH A;  1FGR A;  3V92 A;  2FFZ A;  1N8S A;  5FBF A;  1RRH A;  2LRG A;  3CWZ B;  3IBZ A;  2IUK A;  1FGO A;  5EEO A;  2SBL A;  1CA1 A;  2QNG A;  1Y4K A;  1AK0 A;  1RRL A;  1W52 X;  1ETH A;  4DJ4 A;  3W52 A;  2LG7 A;  2OXE A;  1JNQ A;  3BNB A;  1P6E A;  3SNG A;  2IUJ A;  2LGE A;  1HPL A;  2KXV A;  4NRE A;  4QWT A;  1FGM A;  2PVS A;  1GYG A;  2XFD A;  2XHJ A;  5FB9 A;  4CWM A;  2KXT A;  3VF1 A;  2HUC A;  1LOX A;  1P5X A;  1N8Q A;  3FG3 A;  1ROV A;  3BNC A;  3U6G A;  4JDG A; 
#chains in the Genus database with same CATH homology
 2WXU A;  5FBG A;  1GPL A;  2FGN A;  1NO3 A;  3BND A;  2PPL A;  1FGT A;  3V98 A;  1P6D A;  2FNQ A;  4WHA A;  1QMD A;  1LPB B;  5FBC A;  4CXP A;  1LPA B;  1RP1 A;  3PZW A;  5FBB A;  3O8Y A;  3V99 A;  5FBD A;  3FG4 A;  1IK3 A;  2WY6 A;  1YGE A;  1AH7 A;  1KHO A;  1FGQ A;  4CXO A;  1LNH A;  1QM6 A;  1HU9 A;  5FBA A;  3BNE A;  2WXT A;  4CXV A;  1BU8 A;  4WFO A;  3FG1 A;  1F8N A;  2P0M A;  1OLP A;  1FGR A;  3V92 A;  2FFZ A;  1N8S A;  5FBF A;  1RRH A;  3CWZ B;  2IUK A;  1FGO A;  5EEO A;  2SBL A;  1CA1 A;  1Y4K A;  1AK0 A;  1RRL A;  1W52 X;  1ETH A;  4DJ4 A;  3W52 A;  2OXE A;  1JNQ A;  3BNB A;  1P6E A;  3SNG A;  2IUJ A;  1HPL A;  4QWT A;  4NRE A;  1FGM A;  2PVS A;  1GYG A;  5FB9 A;  4CWM A;  3VF1 A;  2HUC A;  1LOX A;  1P5X A;  1N8Q A;  3FG3 A;  1ROV A;  3BNC A;  4JDG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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