1KU6B

Fasciculin 2-mouse acetylcholinesterase complex
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
61
structure length
61
Chain Sequence
TMCYSHTTTSRAILTNCGENSCYRKSRRHPPKMVLGRGCGCPPGDDNLEVKCCTSPDKCNY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insights into ligand interactions at the acetylcholinesterase peripheral anionic site.
pubmed doi rcsb
molecule keywords ACETYLCHOLINESTERASE
molecule tags Hydrolase/toxin
source organism Mus musculus
total genus 10
structure length 61
sequence length 61
ec nomenclature
pdb deposition date 2002-01-21
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.60.10 Mainly Beta Ribbon CD59 CD59 1ku6B00
3NDSA 5DU1A 2QJBC 1KFHA 2I9BE 1S4YA 1JGKA 1KTZB 1HOYA 1L4WA 1ZADA 3PLCA 1RL5A 2CCXA 2PJYC 3BT1U 2FD6U 2L5SA 1KXIA 1IJCA 1H0JA 1FASA 1HAAA 1CXOA 4OM5A 2X8BB 4DO8A 3NH7A 1KL8A 1MR6A 2QC1A 2H64C 1HC9B 2N99A 2GOOC 1KS6A 1NEAA 3LAQU 1W6BA 1IK8A 1ABTA 1ERGA 2H7ZB 3EVSC 4P7UA 1IDIA 1LSIA 1PLOA 1NORA 1TXBA 1COEA 2NBTA 1CHVS 1DRSA 3HH7A 4OM4A 1NTNA 4XJJA 1BTEA 1IDLA 1V6PA 1CREA 1B41B 5EBXA 4HQPF 1QM7A 1CODA 1NTXA 1RGJA 1XT3A 2LCRA 1CRFA 1TXAA 2MUOA 3KFDI 3U74U 2LA1A 1JBDA 1IKCA 1KBAA 2OFSA 1FF4A 4LFTA 4EY8B 5IMTD 1ONJA 1KU6B 3QB4B 1M9ZA 2H5FA 1NYUA 2BTXA 1G6MA 1TGXA 1ES7B 2MJ0A 2HLRA 2JQPA 3FEVA 1CB9A 3KFDE 1FFJA 2CDXA 2ABXA 1F94A 2K3GA 2CRTA 1NYSA 3BT2U 1CVOA 1IDHA 2MFAA 1IDGA 2MJYA 4UY2C 4QTIU 1JE9A 1KBSA 1F8UB 1LJZA 4BIKB 2JVEA 2PJYB 1QKEA 2J8BA 1LXHA 1NXBA 1KBTA 1IQ9A 5DZ5A 3VTSA 1YWHA 1CCQA 2MJ4A 1LX5B 3EBXA 1HAJA 2VLWA 2BHIA 1CDSA 2MUPA 1REWC 4FAOE 1CTXA 2H64B 1CXNA 1MAHF 1FRAA 2GOOB 2L03A 2CRSA 1KC4A 1FSSB 4ZQYA 1UG4A 1QKDA 1ERAA 2HLQA 4FAOC 2ERAA 4BDTB 2UWRA 4IYEA 2H62C 2UX2A 1CDRA 5IMYC 1CDQA 3NEQA 1I02A 1LXGA 2H62D 4AEAA 1BXPA 2H8UA 3U73U 3ERAA 2CTXA 1CDTA 2QJAC 1HC9A 1FSCA 1TFSA 4RUDA 6EBXA 5DO6A 1VB0A 2QJ9C 2H7ZA 2MHYA
chains in the Genus database with same CATH superfamily
3NDSA 5DU1A 2QJBC 1KFHA 2I9BE 1S4YA 1JGKA 1KTZB 1HOYA 1L4WA 1ZADA 3PLCA 1RL5A 2CCXA 2PJYC 3BT1U 2FD6U 2L5SA 1KXIA 1IJCA 1H0JA 1FASA 1HAAA 1CXOA 4OM5A 2X8BB 4DO8A 3NH7A 1KL8A 1MR6A 2QC1A 2H64C 1HC9B 2N99A 2GOOC 1KS6A 1NEAA 3LAQU 1W6BA 1IK8A 1ABTA 1ERGA 2H7ZB 3EVSC 4P7UA 1IDIA 1LSIA 1PLOA 1NORA 1TXBA 1COEA 2NBTA 1CHVS 1DRSA 3HH7A 4OM4A 1NTNA 4XJJA 1BTEA 1IDLA 1V6PA 1CREA 1B41B 5EBXA 4HQPF 1QM7A 1CODA 1NTXA 1RGJA 1XT3A 2LCRA 1CRFA 1TXAA 2MUOA 3KFDI 3U74U 2LA1A 1JBDA 1IKCA 1KBAA 2OFSA 1FF4A 4LFTA 4EY8B 5IMTD 1ONJA 1KU6B 3QB4B 1M9ZA 2H5FA 1NYUA 2BTXA 1G6MA 1TGXA 1ES7B 2MJ0A 2HLRA 2JQPA 3FEVA 1CB9A 3KFDE 1FFJA 2CDXA 2ABXA 1F94A 2K3GA 2CRTA 1NYSA 3BT2U 1CVOA 4KSNA 1IDHA 2MFAA 1IDGA 2MJYA 4UY2C 4QTIU 1JE9A 1KBSA 1F8UB 1LJZA 4BIKB 2JVEA 2PJYB 1QKEA 2J8BA 1LXHA 1NXBA 1KBTA 1IQ9A 5DZ5A 3VTSA 1YWHA 1CCQA 2MJ4A 1LX5B 3EBXA 1HAJA 2VLWA 2BHIA 1CDSA 2MUPA 1REWC 4FAOE 1CTXA 2H64B 1CXNA 1MAHF 1FRAA 2GOOB 2L03A 2CRSA 1KC4A 1FSSB 4ZQYA 1UG4A 1QKDA 1ERAA 2HLQA 4FAOC 2ERAA 4BDTB 2UWRA 4IYEA 2H62C 2UX2A 1CDRA 5IMYC 1CDQA 3NEQA 1I02A 1LXGA 2H62D 4AEAA 1BXPA 2H8UA 3U73U 3ERAA 2CTXA 1CDTA 2QJAC 1HC9A 1FSCA 1TFSA 4RUDA 6EBXA 5DO6A 1VB0A 2QJ9C 2H7ZA 2MHYA
chains in the Genus database with same CATH topology
3NDSA 5DU1A 2QJBC 1KFHA 2I9BE 1S4YA 1JGKA 1KTZB 1HOYA 1L4WA 1ZADA 3PLCA 1RL5A 2CCXA 2PJYC 3BT1U 2FD6U 2L5SA 1KXIA 1IJCA 1H0JA 1FASA 1HAAA 1CXOA 4OM5A 2X8BB 4DO8A 3NH7A 1KL8A 1MR6A 2QC1A 2H64C 1HC9B 2N99A 2GOOC 1KS6A 1NEAA 3LAQU 1W6BA 1IK8A 1ABTA 1ERGA 2H7ZB 3EVSC 4P7UA 1IDIA 1LSIA 1PLOA 1NORA 1TXBA 1COEA 2NBTA 1CHVS 1DRSA 3HH7A 4OM4A 1NTNA 4XJJA 1BTEA 1IDLA 1V6PA 1CREA 1B41B 5EBXA 4HQPF 1QM7A 1CODA 1NTXA 1RGJA 1XT3A 2LCRA 1CRFA 1TXAA 2MUOA 3KFDI 3U74U 2LA1A 1JBDA 1IKCA 1KBAA 2OFSA 1FF4A 4LFTA 4EY8B 5IMTD 1ONJA 1KU6B 3QB4B 1M9ZA 2H5FA 1NYUA 2BTXA 1G6MA 1TGXA 1ES7B 2MJ0A 2HLRA 2JQPA 3FEVA 1CB9A 3KFDE 1FFJA 2CDXA 2ABXA 1F94A 2K3GA 2CRTA 1NYSA 3BT2U 1CVOA 4KSNA 1IDHA 2MFAA 1IDGA 2MJYA 4UY2C 4QTIU 1JE9A 1KBSA 1F8UB 1LJZA 4BIKB 2JVEA 2PJYB 1QKEA 2J8BA 1LXHA 1NXBA 1KBTA 1IQ9A 5DZ5A 3VTSA 1YWHA 1CCQA 2MJ4A 1LX5B 3EBXA 1HAJA 2VLWA 2BHIA 1CDSA 2MUPA 1REWC 4FAOE 1CTXA 2H64B 1CXNA 1MAHF 1FRAA 2GOOB 2L03A 2CRSA 1KC4A 1FSSB 4ZQYA 1UG4A 1QKDA 1ERAA 2HLQA 4FAOC 2ERAA 4BDTB 2UWRA 4IYEA 2H62C 2UX2A 1CDRA 5IMYC 1CDQA 3NEQA 1I02A 1LXGA 2H62D 4AEAA 1BXPA 2H8UA 3U73U 3ERAA 2CTXA 1CDTA 2QJAC 1HC9A 1FSCA 1TFSA 4RUDA 6EBXA 5DO6A 1VB0A 2QJ9C 2H7ZA 2MHYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3NDS A;  5DU1 A;  2QJB C;  1KFH A;  2I9B E;  1S4Y A;  1JGK A;  1KTZ B;  1HOY A;  1L4W A;  1ZAD A;  3PLC A;  1RL5 A;  2CCX A;  2PJY C;  3BT1 U;  2FD6 U;  2L5S A;  1KXI A;  1IJC A;  1H0J A;  1FAS A;  1HAA A;  1CXO A;  4OM5 A;  2X8B B;  4DO8 A;  3NH7 A;  1KL8 A;  1MR6 A;  2QC1 A;  2H64 C;  1HC9 B;  2N99 A;  2GOO C;  1KS6 A;  1NEA A;  3LAQ U;  1W6B A;  1IK8 A;  1ABT A;  1ERG A;  2H7Z B;  3EVS C;  4P7U A;  1IDI A;  1LSI A;  1PLO A;  1NOR A;  1TXB A;  1COE A;  2NBT A;  1CHV S;  1DRS A;  3HH7 A;  4OM4 A;  1NTN A;  4XJJ A;  1BTE A;  1IDL A;  1V6P A;  1CRE A;  1B41 B;  5EBX A;  4HQP F;  1QM7 A;  1COD A;  1NTX A;  1RGJ A;  1XT3 A;  2LCR A;  1CRF A;  1TXA A;  2MUO A;  3KFD I;  3U74 U;  2LA1 A;  1JBD A;  1IKC A;  1KBA A;  2OFS A;  1FF4 A;  4LFT A;  4EY8 B;  5IMT D;  1ONJ A;  1KU6 B;  3QB4 B;  1M9Z A;  2H5F A;  1NYU A;  2BTX A;  1G6M A;  1TGX A;  1ES7 B;  2MJ0 A;  2HLR A;  2JQP A;  3FEV A;  1CB9 A;  3KFD E;  1FFJ A;  2CDX A;  2ABX A;  1F94 A;  2K3G A;  2CRT A;  1NYS A;  3BT2 U;  1CVO A;  1IDH A;  2MFA A;  1IDG A;  2MJY A;  4UY2 C;  4QTI U;  1JE9 A;  1KBS A;  1F8U B;  1LJZ A;  4BIK B;  2JVE A;  2PJY B;  1QKE A;  2J8B A;  1LXH A;  1NXB A;  1KBT A;  1IQ9 A;  5DZ5 A;  3VTS A;  1YWH A;  1CCQ A;  2MJ4 A;  1LX5 B;  3EBX A;  1HAJ A;  2VLW A;  2BHI A;  1CDS A;  2MUP A;  1REW C;  4FAO E;  1CTX A;  2H64 B;  1CXN A;  1MAH F;  1FRA A;  2GOO B;  2L03 A;  2CRS A;  1KC4 A;  1FSS B;  4ZQY A;  1UG4 A;  1QKD A;  1ERA A;  2HLQ A;  4FAO C;  2ERA A;  4BDT B;  2UWR A;  4IYE A;  2H62 C;  2UX2 A;  1CDR A;  5IMY C;  1CDQ A;  3NEQ A;  1I02 A;  1LXG A;  2H62 D;  4AEA A;  1BXP A;  2H8U A;  3U73 U;  3ERA A;  2CTX A;  1CDT A;  2QJA C;  1HC9 A;  1FSC A;  1TFS A;  4RUD A;  6EBX A;  5DO6 A;  1VB0 A;  2QJ9 C;  2H7Z A;  2MHY A; 
#chains in the Genus database with same CATH topology
 3NDS A;  5DU1 A;  2QJB C;  1KFH A;  2I9B E;  1S4Y A;  1JGK A;  1KTZ B;  1HOY A;  1L4W A;  1ZAD A;  3PLC A;  1RL5 A;  2CCX A;  2PJY C;  3BT1 U;  2FD6 U;  2L5S A;  1KXI A;  1IJC A;  1H0J A;  1FAS A;  1HAA A;  1CXO A;  4OM5 A;  2X8B B;  4DO8 A;  3NH7 A;  1KL8 A;  1MR6 A;  2QC1 A;  2H64 C;  1HC9 B;  2N99 A;  2GOO C;  1KS6 A;  1NEA A;  3LAQ U;  1W6B A;  1IK8 A;  1ABT A;  1ERG A;  2H7Z B;  3EVS C;  4P7U A;  1IDI A;  1LSI A;  1PLO A;  1NOR A;  1TXB A;  1COE A;  2NBT A;  1CHV S;  1DRS A;  3HH7 A;  4OM4 A;  1NTN A;  4XJJ A;  1BTE A;  1IDL A;  1V6P A;  1CRE A;  1B41 B;  5EBX A;  4HQP F;  1QM7 A;  1COD A;  1NTX A;  1RGJ A;  1XT3 A;  2LCR A;  1CRF A;  1TXA A;  2MUO A;  3KFD I;  3U74 U;  2LA1 A;  1JBD A;  1IKC A;  1KBA A;  2OFS A;  1FF4 A;  4LFT A;  4EY8 B;  5IMT D;  1ONJ A;  1KU6 B;  3QB4 B;  1M9Z A;  2H5F A;  1NYU A;  2BTX A;  1G6M A;  1TGX A;  1ES7 B;  2MJ0 A;  2HLR A;  2JQP A;  3FEV A;  1CB9 A;  3KFD E;  1FFJ A;  2CDX A;  2ABX A;  1F94 A;  2K3G A;  2CRT A;  1NYS A;  3BT2 U;  1CVO A;  4KSN A;  1IDH A;  2MFA A;  1IDG A;  2MJY A;  4UY2 C;  4QTI U;  1JE9 A;  1KBS A;  1F8U B;  1LJZ A;  4BIK B;  2JVE A;  2PJY B;  1QKE A;  2J8B A;  1LXH A;  1NXB A;  1KBT A;  1IQ9 A;  5DZ5 A;  3VTS A;  1YWH A;  1CCQ A;  2MJ4 A;  1LX5 B;  3EBX A;  1HAJ A;  2VLW A;  2BHI A;  1CDS A;  2MUP A;  1REW C;  4FAO E;  1CTX A;  2H64 B;  1CXN A;  1MAH F;  1FRA A;  2GOO B;  2L03 A;  2CRS A;  1KC4 A;  1FSS B;  4ZQY A;  1UG4 A;  1QKD A;  1ERA A;  2HLQ A;  4FAO C;  2ERA A;  4BDT B;  2UWR A;  4IYE A;  2H62 C;  2UX2 A;  1CDR A;  5IMY C;  1CDQ A;  3NEQ A;  1I02 A;  1LXG A;  2H62 D;  4AEA A;  1BXP A;  2H8U A;  3U73 U;  3ERA A;  2CTX A;  1CDT A;  2QJA C;  1HC9 A;  1FSC A;  1TFS A;  4RUD A;  6EBX A;  5DO6 A;  1VB0 A;  2QJ9 C;  2H7Z A;  2MHY A; 
#chains in the Genus database with same CATH homology
 3NDS A;  5DU1 A;  2QJB C;  1KFH A;  2I9B E;  1S4Y A;  1JGK A;  1KTZ B;  1HOY A;  1L4W A;  1ZAD A;  3PLC A;  1RL5 A;  2CCX A;  2PJY C;  3BT1 U;  2FD6 U;  2L5S A;  1KXI A;  1IJC A;  1H0J A;  1FAS A;  1HAA A;  1CXO A;  4OM5 A;  2X8B B;  4DO8 A;  3NH7 A;  1KL8 A;  1MR6 A;  2QC1 A;  2H64 C;  1HC9 B;  2N99 A;  2GOO C;  1KS6 A;  1NEA A;  3LAQ U;  1W6B A;  1IK8 A;  1ABT A;  1ERG A;  2H7Z B;  3EVS C;  4P7U A;  1IDI A;  1LSI A;  1PLO A;  1NOR A;  1TXB A;  1COE A;  2NBT A;  1CHV S;  1DRS A;  3HH7 A;  4OM4 A;  1NTN A;  4XJJ A;  1BTE A;  1IDL A;  1V6P A;  1CRE A;  1B41 B;  5EBX A;  4HQP F;  1QM7 A;  1COD A;  1NTX A;  1RGJ A;  1XT3 A;  2LCR A;  1CRF A;  1TXA A;  2MUO A;  3KFD I;  3U74 U;  2LA1 A;  1JBD A;  1IKC A;  1KBA A;  2OFS A;  1FF4 A;  4LFT A;  4EY8 B;  5IMT D;  1ONJ A;  1KU6 B;  3QB4 B;  1M9Z A;  2H5F A;  1NYU A;  2BTX A;  1G6M A;  1TGX A;  1ES7 B;  2MJ0 A;  2HLR A;  2JQP A;  3FEV A;  1CB9 A;  3KFD E;  1FFJ A;  2CDX A;  2ABX A;  1F94 A;  2K3G A;  2CRT A;  1NYS A;  3BT2 U;  1CVO A;  4KSN A;  1IDH A;  2MFA A;  1IDG A;  2MJY A;  4UY2 C;  4QTI U;  1JE9 A;  1KBS A;  1F8U B;  1LJZ A;  4BIK B;  2JVE A;  2PJY B;  1QKE A;  2J8B A;  1LXH A;  1NXB A;  1KBT A;  1IQ9 A;  5DZ5 A;  3VTS A;  1YWH A;  1CCQ A;  2MJ4 A;  1LX5 B;  3EBX A;  1HAJ A;  2VLW A;  2BHI A;  1CDS A;  2MUP A;  1REW C;  4FAO E;  1CTX A;  2H64 B;  1CXN A;  1MAH F;  1FRA A;  2GOO B;  2L03 A;  2CRS A;  1KC4 A;  1FSS B;  4ZQY A;  1UG4 A;  1QKD A;  1ERA A;  2HLQ A;  4FAO C;  2ERA A;  4BDT B;  2UWR A;  4IYE A;  2H62 C;  2UX2 A;  1CDR A;  5IMY C;  1CDQ A;  3NEQ A;  1I02 A;  1LXG A;  2H62 D;  4AEA A;  1BXP A;  2H8U A;  3U73 U;  3ERA A;  2CTX A;  1CDT A;  2QJA C;  1HC9 A;  1FSC A;  1TFS A;  4RUD A;  6EBX A;  5DO6 A;  1VB0 A;  2QJ9 C;  2H7Z A;  2MHY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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