1KU6B

Fasciculin 2-mouse acetylcholinesterase complex
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
61
structure length
61
Chain Sequence
TMCYSHTTTSRAILTNCGENSCYRKSRRHPPKMVLGRGCGCPPGDDNLEVKCCTSPDKCNY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords ACETYLCHOLINESTERASE
publication title Structural insights into ligand interactions at the acetylcholinesterase peripheral anionic site.
pubmed doi rcsb
source organism Mus musculus
molecule tags Hydrolase/toxin
total genus 10
structure length 61
sequence length 61
ec nomenclature
pdb deposition date 2002-01-21
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.60.10 Mainly Beta Ribbon CD59 CD59 1ku6B00
4OM5A 1IKCA 1IK8A 1HOYA 2ERAA 4UY2C 2BTXA 1TGXA 3QB4B 3BT1U 1FF4A 1KXIA 2UWRA 1F94A 4EY8B 4IYEA 2K3GA 1HC9B 2H62D 2QJ9C 2J8BA 2CRSA 2L03A 1LXGA 1V6PA 3EBXA 1CVOA 2OFSA 1UG4A 3BT2U 1HAAA 2N99A 2QJAC 3NDSA 2H8UA 1LXHA 1M9ZA 5DU1A 3FEVA 1FASA 2MJ0A 2MJYA 1KBSA 2JQPA 4P7UA 1DRSA 1ERGA 4XJJA 1NYUA 2H62C 2CDXA 4FAOC 1XT3A 2HLRA 4HQPF 3NEQA 1JBDA 5IMYC 2MUOA 1W6BA 1NXBA 1TXAA 1NTNA 5DZ5A 1CB9A 1CXOA 1IDIA 3HH7A 3PLCA 2CTXA 2GOOB 3VTSA 2VLWA 1FFJA 2QC1A 4RUDA 1YWHA 1LX5B 2H5FA 1IJCA 1RGJA 1IDLA 1KL8A 2UX2A 1VB0A 1CDRA 2FD6U 1IDGA 1TFSA 1QKDA 4QTIU 3EVSC 1MAHF 1MR6A 1F8UB 1NYSA 2MJ4A 2GOOC 1HAJA 2PJYB 1KFHA 2MUPA 1CCQA 5IMTD 1KTZB 1QM7A 1LJZA 2MHYA 1CODA 2BHIA 4FAOE 2NBTA 2QJBC 2CCXA 1G6MA 1BXPA 2JVEA 2X8BB 2MFAA 2LCRA 1REWC 4AEAA 1KU6B 1BTEA 1CDQA 1QKEA 1S4YA 2LA1A 2PJYC 4BDTB 3ERAA 1ERAA 1FRAA 1RL5A 1I02A 2ABXA 2H7ZA 6EBXA 1KBTA 1ONJA 1FSCA 3KFDE 1FSSB 4DO8A 1CXNA 1ABTA 1JGKA 5EBXA 2L5SA 1PLOA 2H7ZB 1CDSA 1KC4A 5DO6A 1HC9A 1LSIA 3U74U 1CDTA 1CRFA 1CTXA 3LAQU 3NH7A 2H64B 4ZQYA 1KBAA 1NEAA 1B41B 2CRTA 2I9BE 1NTXA 2HLQA 1CREA 1L4WA 1TXBA 1ES7B 4LFTA 1JE9A 3KFDI 1KS6A 1CHVS 4BIKB 3U73U 1H0JA 1NORA 2H64C 4OM4A 1COEA 1IDHA 1IQ9A 1ZADA
chains in the Genus database with same CATH superfamily
4OM5A 1IKCA 1IK8A 1HOYA 2ERAA 4UY2C 2BTXA 1TGXA 3QB4B 3BT1U 1FF4A 1KXIA 2UWRA 1F94A 4EY8B 4IYEA 2K3GA 1HC9B 2H62D 2QJ9C 2J8BA 2CRSA 2L03A 1LXGA 1V6PA 3EBXA 1CVOA 2OFSA 1UG4A 3BT2U 1HAAA 2N99A 2QJAC 3NDSA 2H8UA 1LXHA 1M9ZA 5DU1A 3FEVA 1FASA 2MJ0A 2MJYA 1KBSA 2JQPA 4P7UA 1DRSA 1ERGA 4XJJA 1NYUA 2H62C 2CDXA 4FAOC 1XT3A 2HLRA 4HQPF 3NEQA 1JBDA 5IMYC 2MUOA 1W6BA 1NXBA 1TXAA 1NTNA 5DZ5A 1CB9A 1CXOA 1IDIA 3HH7A 3PLCA 2CTXA 2GOOB 3VTSA 2VLWA 1FFJA 2QC1A 4RUDA 1YWHA 1LX5B 2H5FA 1IJCA 1RGJA 1IDLA 1KL8A 2UX2A 1VB0A 1CDRA 2FD6U 1IDGA 1TFSA 1QKDA 4QTIU 3EVSC 1MAHF 1MR6A 1F8UB 1NYSA 2MJ4A 2GOOC 1HAJA 2PJYB 1KFHA 2MUPA 1CCQA 5IMTD 1KTZB 1QM7A 1LJZA 2MHYA 1CODA 2BHIA 4FAOE 2NBTA 2QJBC 2CCXA 1G6MA 1BXPA 2JVEA 2X8BB 2MFAA 2LCRA 1REWC 4AEAA 1KU6B 1BTEA 1CDQA 1QKEA 1S4YA 2LA1A 2PJYC 4BDTB 3ERAA 1ERAA 1FRAA 1RL5A 1I02A 2ABXA 2H7ZA 6EBXA 1KBTA 1ONJA 1FSCA 3KFDE 1FSSB 4DO8A 1CXNA 1ABTA 1JGKA 5EBXA 2L5SA 1PLOA 2H7ZB 1CDSA 4KSNA 1KC4A 5DO6A 1HC9A 1LSIA 3U74U 1CDTA 1CRFA 1CTXA 3LAQU 3NH7A 2H64B 4ZQYA 1KBAA 1NEAA 1B41B 2CRTA 2I9BE 1NTXA 2HLQA 1CREA 1L4WA 1TXBA 1ES7B 4LFTA 1JE9A 3KFDI 1KS6A 1CHVS 4BIKB 3U73U 1H0JA 1NORA 2H64C 4OM4A 1COEA 1IDHA 1IQ9A 1ZADA
chains in the Genus database with same CATH topology
4OM5A 1IKCA 1IK8A 1HOYA 2ERAA 4UY2C 2BTXA 1TGXA 3QB4B 3BT1U 1FF4A 1KXIA 2UWRA 1F94A 4EY8B 4IYEA 2K3GA 1HC9B 2H62D 2QJ9C 2J8BA 2CRSA 2L03A 1LXGA 1V6PA 3EBXA 1CVOA 2OFSA 1UG4A 3BT2U 1HAAA 2N99A 2QJAC 3NDSA 2H8UA 1LXHA 1M9ZA 5DU1A 3FEVA 1FASA 2MJ0A 2MJYA 1KBSA 2JQPA 4P7UA 1DRSA 1ERGA 4XJJA 1NYUA 2H62C 2CDXA 4FAOC 1XT3A 2HLRA 4HQPF 3NEQA 1JBDA 5IMYC 2MUOA 1W6BA 1NXBA 1TXAA 1NTNA 5DZ5A 1CB9A 1CXOA 1IDIA 3HH7A 3PLCA 2CTXA 2GOOB 3VTSA 2VLWA 1FFJA 2QC1A 4RUDA 1YWHA 1LX5B 2H5FA 1IJCA 1RGJA 1IDLA 1KL8A 2UX2A 1VB0A 1CDRA 2FD6U 1IDGA 1TFSA 1QKDA 4QTIU 3EVSC 1MAHF 1MR6A 1F8UB 1NYSA 2MJ4A 2GOOC 1HAJA 2PJYB 1KFHA 2MUPA 1CCQA 5IMTD 1KTZB 1QM7A 1LJZA 2MHYA 1CODA 2BHIA 4FAOE 2NBTA 2QJBC 2CCXA 1G6MA 1BXPA 2JVEA 2X8BB 2MFAA 2LCRA 1REWC 4AEAA 1KU6B 1BTEA 1CDQA 1QKEA 1S4YA 2LA1A 2PJYC 4BDTB 3ERAA 1ERAA 1FRAA 1RL5A 1I02A 2ABXA 2H7ZA 6EBXA 1KBTA 1ONJA 1FSCA 3KFDE 1FSSB 4DO8A 1CXNA 1ABTA 1JGKA 5EBXA 2L5SA 1PLOA 2H7ZB 1CDSA 4KSNA 1KC4A 5DO6A 1HC9A 1LSIA 3U74U 1CDTA 1CRFA 1CTXA 3LAQU 3NH7A 2H64B 4ZQYA 1KBAA 1NEAA 1B41B 2CRTA 2I9BE 1NTXA 2HLQA 1CREA 1L4WA 1TXBA 1ES7B 4LFTA 1JE9A 3KFDI 1KS6A 1CHVS 4BIKB 3U73U 1H0JA 1NORA 2H64C 4OM4A 1COEA 1IDHA 1IQ9A 1ZADA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4OM5 A;  1IKC A;  1IK8 A;  1HOY A;  2ERA A;  4UY2 C;  2BTX A;  1TGX A;  3QB4 B;  3BT1 U;  1FF4 A;  1KXI A;  2UWR A;  1F94 A;  4EY8 B;  4IYE A;  2K3G A;  1HC9 B;  2H62 D;  2QJ9 C;  2J8B A;  2CRS A;  2L03 A;  1LXG A;  1V6P A;  3EBX A;  1CVO A;  2OFS A;  1UG4 A;  3BT2 U;  1HAA A;  2N99 A;  2QJA C;  3NDS A;  2H8U A;  1LXH A;  1M9Z A;  5DU1 A;  3FEV A;  1FAS A;  2MJ0 A;  2MJY A;  1KBS A;  2JQP A;  4P7U A;  1DRS A;  1ERG A;  4XJJ A;  1NYU A;  2H62 C;  2CDX A;  4FAO C;  1XT3 A;  2HLR A;  4HQP F;  3NEQ A;  1JBD A;  5IMY C;  2MUO A;  1W6B A;  1NXB A;  1TXA A;  1NTN A;  5DZ5 A;  1CB9 A;  1CXO A;  1IDI A;  3HH7 A;  3PLC A;  2CTX A;  2GOO B;  3VTS A;  2VLW A;  1FFJ A;  2QC1 A;  4RUD A;  1YWH A;  1LX5 B;  2H5F A;  1IJC A;  1RGJ A;  1IDL A;  1KL8 A;  2UX2 A;  1VB0 A;  1CDR A;  2FD6 U;  1IDG A;  1TFS A;  1QKD A;  4QTI U;  3EVS C;  1MAH F;  1MR6 A;  1F8U B;  1NYS A;  2MJ4 A;  2GOO C;  1HAJ A;  2PJY B;  1KFH A;  2MUP A;  1CCQ A;  5IMT D;  1KTZ B;  1QM7 A;  1LJZ A;  2MHY A;  1COD A;  2BHI A;  4FAO E;  2NBT A;  2QJB C;  2CCX A;  1G6M A;  1BXP A;  2JVE A;  2X8B B;  2MFA A;  2LCR A;  1REW C;  4AEA A;  1KU6 B;  1BTE A;  1CDQ A;  1QKE A;  1S4Y A;  2LA1 A;  2PJY C;  4BDT B;  3ERA A;  1ERA A;  1FRA A;  1RL5 A;  1I02 A;  2ABX A;  2H7Z A;  6EBX A;  1KBT A;  1ONJ A;  1FSC A;  3KFD E;  1FSS B;  4DO8 A;  1CXN A;  1ABT A;  1JGK A;  5EBX A;  2L5S A;  1PLO A;  2H7Z B;  1CDS A;  1KC4 A;  5DO6 A;  1HC9 A;  1LSI A;  3U74 U;  1CDT A;  1CRF A;  1CTX A;  3LAQ U;  3NH7 A;  2H64 B;  4ZQY A;  1KBA A;  1NEA A;  1B41 B;  2CRT A;  2I9B E;  1NTX A;  2HLQ A;  1CRE A;  1L4W A;  1TXB A;  1ES7 B;  4LFT A;  1JE9 A;  3KFD I;  1KS6 A;  1CHV S;  4BIK B;  3U73 U;  1H0J A;  1NOR A;  2H64 C;  4OM4 A;  1COE A;  1IDH A;  1IQ9 A;  1ZAD A; 
#chains in the Genus database with same CATH topology
 4OM5 A;  1IKC A;  1IK8 A;  1HOY A;  2ERA A;  4UY2 C;  2BTX A;  1TGX A;  3QB4 B;  3BT1 U;  1FF4 A;  1KXI A;  2UWR A;  1F94 A;  4EY8 B;  4IYE A;  2K3G A;  1HC9 B;  2H62 D;  2QJ9 C;  2J8B A;  2CRS A;  2L03 A;  1LXG A;  1V6P A;  3EBX A;  1CVO A;  2OFS A;  1UG4 A;  3BT2 U;  1HAA A;  2N99 A;  2QJA C;  3NDS A;  2H8U A;  1LXH A;  1M9Z A;  5DU1 A;  3FEV A;  1FAS A;  2MJ0 A;  2MJY A;  1KBS A;  2JQP A;  4P7U A;  1DRS A;  1ERG A;  4XJJ A;  1NYU A;  2H62 C;  2CDX A;  4FAO C;  1XT3 A;  2HLR A;  4HQP F;  3NEQ A;  1JBD A;  5IMY C;  2MUO A;  1W6B A;  1NXB A;  1TXA A;  1NTN A;  5DZ5 A;  1CB9 A;  1CXO A;  1IDI A;  3HH7 A;  3PLC A;  2CTX A;  2GOO B;  3VTS A;  2VLW A;  1FFJ A;  2QC1 A;  4RUD A;  1YWH A;  1LX5 B;  2H5F A;  1IJC A;  1RGJ A;  1IDL A;  1KL8 A;  2UX2 A;  1VB0 A;  1CDR A;  2FD6 U;  1IDG A;  1TFS A;  1QKD A;  4QTI U;  3EVS C;  1MAH F;  1MR6 A;  1F8U B;  1NYS A;  2MJ4 A;  2GOO C;  1HAJ A;  2PJY B;  1KFH A;  2MUP A;  1CCQ A;  5IMT D;  1KTZ B;  1QM7 A;  1LJZ A;  2MHY A;  1COD A;  2BHI A;  4FAO E;  2NBT A;  2QJB C;  2CCX A;  1G6M A;  1BXP A;  2JVE A;  2X8B B;  2MFA A;  2LCR A;  1REW C;  4AEA A;  1KU6 B;  1BTE A;  1CDQ A;  1QKE A;  1S4Y A;  2LA1 A;  2PJY C;  4BDT B;  3ERA A;  1ERA A;  1FRA A;  1RL5 A;  1I02 A;  2ABX A;  2H7Z A;  6EBX A;  1KBT A;  1ONJ A;  1FSC A;  3KFD E;  1FSS B;  4DO8 A;  1CXN A;  1ABT A;  1JGK A;  5EBX A;  2L5S A;  1PLO A;  2H7Z B;  1CDS A;  4KSN A;  1KC4 A;  5DO6 A;  1HC9 A;  1LSI A;  3U74 U;  1CDT A;  1CRF A;  1CTX A;  3LAQ U;  3NH7 A;  2H64 B;  4ZQY A;  1KBA A;  1NEA A;  1B41 B;  2CRT A;  2I9B E;  1NTX A;  2HLQ A;  1CRE A;  1L4W A;  1TXB A;  1ES7 B;  4LFT A;  1JE9 A;  3KFD I;  1KS6 A;  1CHV S;  4BIK B;  3U73 U;  1H0J A;  1NOR A;  2H64 C;  4OM4 A;  1COE A;  1IDH A;  1IQ9 A;  1ZAD A; 
#chains in the Genus database with same CATH homology
 4OM5 A;  1IKC A;  1IK8 A;  1HOY A;  2ERA A;  4UY2 C;  2BTX A;  1TGX A;  3QB4 B;  3BT1 U;  1FF4 A;  1KXI A;  2UWR A;  1F94 A;  4EY8 B;  4IYE A;  2K3G A;  1HC9 B;  2H62 D;  2QJ9 C;  2J8B A;  2CRS A;  2L03 A;  1LXG A;  1V6P A;  3EBX A;  1CVO A;  2OFS A;  1UG4 A;  3BT2 U;  1HAA A;  2N99 A;  2QJA C;  3NDS A;  2H8U A;  1LXH A;  1M9Z A;  5DU1 A;  3FEV A;  1FAS A;  2MJ0 A;  2MJY A;  1KBS A;  2JQP A;  4P7U A;  1DRS A;  1ERG A;  4XJJ A;  1NYU A;  2H62 C;  2CDX A;  4FAO C;  1XT3 A;  2HLR A;  4HQP F;  3NEQ A;  1JBD A;  5IMY C;  2MUO A;  1W6B A;  1NXB A;  1TXA A;  1NTN A;  5DZ5 A;  1CB9 A;  1CXO A;  1IDI A;  3HH7 A;  3PLC A;  2CTX A;  2GOO B;  3VTS A;  2VLW A;  1FFJ A;  2QC1 A;  4RUD A;  1YWH A;  1LX5 B;  2H5F A;  1IJC A;  1RGJ A;  1IDL A;  1KL8 A;  2UX2 A;  1VB0 A;  1CDR A;  2FD6 U;  1IDG A;  1TFS A;  1QKD A;  4QTI U;  3EVS C;  1MAH F;  1MR6 A;  1F8U B;  1NYS A;  2MJ4 A;  2GOO C;  1HAJ A;  2PJY B;  1KFH A;  2MUP A;  1CCQ A;  5IMT D;  1KTZ B;  1QM7 A;  1LJZ A;  2MHY A;  1COD A;  2BHI A;  4FAO E;  2NBT A;  2QJB C;  2CCX A;  1G6M A;  1BXP A;  2JVE A;  2X8B B;  2MFA A;  2LCR A;  1REW C;  4AEA A;  1KU6 B;  1BTE A;  1CDQ A;  1QKE A;  1S4Y A;  2LA1 A;  2PJY C;  4BDT B;  3ERA A;  1ERA A;  1FRA A;  1RL5 A;  1I02 A;  2ABX A;  2H7Z A;  6EBX A;  1KBT A;  1ONJ A;  1FSC A;  3KFD E;  1FSS B;  4DO8 A;  1CXN A;  1ABT A;  1JGK A;  5EBX A;  2L5S A;  1PLO A;  2H7Z B;  1CDS A;  4KSN A;  1KC4 A;  5DO6 A;  1HC9 A;  1LSI A;  3U74 U;  1CDT A;  1CRF A;  1CTX A;  3LAQ U;  3NH7 A;  2H64 B;  4ZQY A;  1KBA A;  1NEA A;  1B41 B;  2CRT A;  2I9B E;  1NTX A;  2HLQ A;  1CRE A;  1L4W A;  1TXB A;  1ES7 B;  4LFT A;  1JE9 A;  3KFD I;  1KS6 A;  1CHV S;  4BIK B;  3U73 U;  1H0J A;  1NOR A;  2H64 C;  4OM4 A;  1COE A;  1IDH A;  1IQ9 A;  1ZAD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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