1LOHA

Streptococcus pneumoniae hyaluronate lyase in complex with hexasaccharide hyaluronan substrate
Total Genus 258
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
258
sequence length
721
structure length
721
Chain Sequence
VKDTYTDRLDDWNGIIAGNQYYDSKNDQMAKLNQELEGKVADSLSSISSQADRIYLWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSMEWMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDPEHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGFYQDGSYIDHTNVAYTGAFGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAPLLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQSDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGFGLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTETDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFLGSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDSKKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYMLIPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVLKRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Hyaluronate Lyase
publication title Mechanism of hyaluronan degradation by Streptococcus pneumoniae hyaluronate lyase. Structures of complexes with the substrate.
pubmed doi rcsb
source organism Streptococcus pneumoniae
molecule tags Lyase
total genus 258
structure length 721
sequence length 721
ec nomenclature ec 4.2.2.1: Hyaluronate lyase.
pdb deposition date 2002-05-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02278 Lyase_8 Polysaccharide lyase family 8, super-sandwich domain
A PF02884 Lyase_8_C Polysaccharide lyase family 8, C-terminal beta-sandwich domain
A PF08124 Lyase_8_N Polysaccharide lyase family 8, N terminal alpha-helical domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.100 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Chondroitin AC/alginate lyase 1lohA02
2.60.220.10 Mainly Beta Sandwich Chondroitinase Ac; Chain A, domain 3 Polysaccharide lyase family 8-like, C-terminal 1lohA03
2.70.98.10 Mainly Beta Distorted Sandwich Beta-galactosidase; Chain A, domain 5 Beta-galactosidase; Chain A, domain 5 1lohA01
1F1SA 1HMUA 3AFLA 2XHNA 5JMFA 3VSNA 1F4HA 1N7OA 3SEPA 1MMYA 1JYVA 2WMKA 4DUWA 4OJZA 2ZQ0A 3Q1NA 1J0MA 1JOVA 5JMDA 1JYWA 1HM2A 1UG9A 3BGAA 3T2PA 1NS2A 4AQ0A 1NSZA 1MMXA 1OJMA 3I3EA 1JYNA 2WW2A 2XSGA 3MUY1 2CIQA 2WW0A 1HN1A 1F9GA 2BRPA 2WMFA 1LXMA 1N7NA 3NJXA 1QAZA 1JZ2A 1YQ2A 2WVZA 3DYMA 1DP0A 2WDAA 1MMUA 3I3BA 2JKAA 2X03A 1NSVA 5E1QA 1JZ6A 1X1HA 3VDCA 2WW3A 1HV6A 1RWGA 3OBAA 1K1XA 3NNBA 4D6CA 1SNZA 2WMIB 1K1WA 1JZ8A 3NREA 2WMHA 1RWFA 2WMGA 2Q1FA 2ZXQA 3A0OA 2BRVX 3T2OA 3T2QA 4D6FA 1L7KA 1L7JA 1JZ7A 4DUXA 2WZSA 4BZGA 3NJVA 4MMHA 2D73A 1NSRA 4TTGA 1NKGA 1LOHA 1ULVA 4NEIA 3IAPA 1RWCA 4OZVA 3VSMA 1NSUA 1PX4A 4D6HA 2CIRA 2E24A 1C82A 2FUQA 3DYOA 1NS0A 3VDAA 3T0BA 4DUVA 4D6EA 3T08A 2WVYA 2BRWA 1NSMA 3OS7A 1LURA 3OB8A 1EGUA 1RWHA 4D6GA 5A1AA 4D6DA 4D71A 3MUZ1 3MWXA 1LXKA 1NSSA 2HTAA 3CZJA 3J7HA 1I8QA 2WW1A 1HMWA 3DCDA 1J0NA 1NSXA 2WCOA 3DECA 3VD7A 1LF9A 1Z45A 3VD5A 1W3YA 1HM3A 4F10A 4F13A 2HTBA 3VD3A 3E7JA 2WMJA 1X1JA 1K1YA 1OJOA 1MMZA 3A24A 1F4AA 3NFVA 1OJPA 3MV11 1N7RA 1YGAA 1PX3A 2JKPA 4RNLA 3T0DA 3IMHA 1RW9A 3VD4A 3VDBA 1HN0A 1JYXA 4D72A 3I3DA 4BZEA 3K25A 3IAQA 4OK4A 1SO0A 3ECQA 4BZHA 3T0AA 1RWAA 4FNVA 3E80A 2FUTA 1NS8A 1LF6A 3E1F1 1X1IA 1JZ4A 1JZ5A 4OK2A 3T09A 1N7QA 2CISA 4MMIA 2WVXA 1CB8A 4OZWA 4BZFA 1NS4A 2JKEA 1TXKA 1N7PA 4E1YA 4D6JA 3DYPA 2E22A 3VD9A 2WVXB 1OJNA 3MV01 4D6IA 2WMIA 1MN0A 3WFAA 1NS7A 1JZ3A
chains in the Genus database with same CATH superfamily
3E32B 1IU7A 2XQWA 4BTXA 5JMFA 2BEDB 1N7OA 4D4AA 4DUWA 1WMOA 1PU4A 5ILYA 1HM2A 1UG9A 1AV4A 4K35A 4GTSB 4AQ0A 2ZISB 1NSZA 1W6JA 3EU8A 1HTYA 3BUBA 1OJMA 3G6JB 1JYNA 4Q2BA 3KBUC 1F9GA 3T33A 1H3AA 1W7CA 2CWTA 3AMOB 1TNYB 3P2CA 3QT9A 3H3KA 5GZKA 2CFWA 4LNBB 3DYMA 1DP0A 1MMUA 3HIIA 3QRYA 3PQIA 2OQEC 1N20A 5IKAA 2BB5A 1HZFA 1D8EB 1X81B 1QSJA 1QWUA 1DYUA 1TNBB 2SQCA 3SQCA 1W2ZA 1FP3A 3EJSA 3RSYA 1K1WA 1W5ZA 1N95B 4KFFA 3WA3A 3NREA 3GLYA 3PMMA 1HCUA 1O6QA 2WMGA 1N4SB 3K7XA 2ALWA 3A3VA 1L7JA 1R33A 1JZ7A 2WZSA 3DX2A 4BZGA 4GTPB 4MMHA 4AYRA 2JG0A 1NKGA 5CA3A 2F7RA 3IAPA 3VSMA 1DCEB 3KLSA 1PX4A 4WVCA 3D3IA 1H36A 3P5RA 4AYQA 5IL3A 5ILDA 2A73B 4DLQA 1O5MB 3Q7FB 2WO0A 3T0UA 2D5JA 1IQXA 3WIRA 2DROA 5JPNB 3T0BA 1SIHA 4DOEA 2F1BA 1X9DA 2V8JA 1OACA 2WVYA 3EJTA 1GHQA 2BRWA 4Z4JA 2V3NA 3K11A 2YFOA 5A1AA 4D6DA 4KFEA 4JJJA 1FBOA 2V8KA 5EAUA 2Y74A 3BVTA 1LXKA 3MUZ1 4FNQA 1N23A 1TN6B 1FT2B 2DRRA 1I8QA 5IKHA 1HMWA 2RDYA 2R2LB 2AHFA 3M74A 1SA4B 1WU6A 2EADA 2DRQA 3DECA 3SAEA 1LF9A 4BZHA 3DRAB 1HM3A 2D1WA 2HTBA 3KQ4A 2ONGA 3VD3A 1KWFA 1MMZA 4BTWA 1HXCA 3NFVA 1RJOA 2F18A 3MV11 3KSQB 3MI6A 4RNLA 1KZOB 2JKPA 3VXDA 1WU5A 3Q73B 3K25A 4BZEA 1FAEA 5FOBB 4OK4A 1IVVA 1D6UA 3AFJA 2V3PA 2B4FA 1RWAA 3BS6A 1NS8A 3M78A 1NL4B 1KZPB 1V5DA 2ZBLA 2WY8A 5E2JA 3T09A 1JZ5A 2CISA 5EATA 1CB8A 1NS4A 2JKEA 1LD7B 1N7PA 2E2VA 1CEMA 1UT9A 3MV01 3SDRA 1AGMA 5CD2A 2WMIA 4M76A 1IVXA 1O7DD 2H6FB 3M71A 1FBWA 1HMUA 3AFLA 3DX1A 3D4ZA 3BUPA 1TQSA 3SEPA 1FMIA 1GXOA 5GY3A 1QX1A 4ZG8A 1JOVA 1TN8B 3M01A 4YDOB 3SDUA 4RNQA 2OKXA 2CWVA 1MMXA 1AYXA 3I3EA 3W5NA 3MUY1 2CIQA 1NXCA 2WW0A 2BRPA 1IS9A 3HXCB 1N7NA 3NJXA 3CU7A 5EASA 1US1A 2H6IB 2CFLA 2WVZA 1MZCB 1FPPB 1IA7A 2WDAA 3W7UA 4DLOA 3W5MA 3S4CA 2C11A 2JKAA 3CZNA 5E1QA 3RRSA 3EJQA 5ILKA 2Z07A 1X1HA 3VDCA 2VN7A 3M7LA 1JRQA 1HXGA 3PZ4B 1TF4A 3BUDA 3NNBA 4D6CA 1G9JA 2WMIB 3E30B 3CZSA 3E73A 2F0YB 2V8IA 4KTPA 3DSVB 2H6HB 4AYOA 1D6ZA 2W0QA 1RWFA 2OW6A 3S4DA 3NBBA 4FNUA 1GAIA 2JJBA 3E34B 3S4AA 3NJVA 3QXQA 1NSRA 4TTGA 1LOHA 3SFYB 1GLMA 1R76A 2DRSA 2XWJB 4ZRQA 2ONHA 3D4YA 4MU9A 1F9OA 3ALAA 2A8ZA 1C82A 1TN7B 2FUQA 1NS0A 3VDAA 2RGKA 3DSTB 2G0DA 3T08A 3WA2X 5M7YA 3OS7A 1XWTA 1LURA 2WOFA 3SDTA 3UD1A 2OQEA 3Q79B 1H39A 1RWHA 4GTVB 1TNUB 2GOXA 3PYAA 4D1IA 4D71A 3MWXA 2HTAA 3ON6A 1NSSA 1H37A 1KS8A 4DODA 4LNGB 3M00A 3E37B 3J7HA 1O1RB 2E2UA 4Z4LA 1H13A 4GTOB 5DGQA 3ANIA 1J0NA 1JCSB 5KKBA 2FBAA 1N9AB 1TQVA 3VD7A 1Z45A 3VD5A 2OOVA 1R34A 3E7JA 3A24A 3ANKA 3WKIA 5GW7A 1KSCA 1F4AA 2KXSA 4V1RA 1SA5B 4D4BA 1OJPA 5IK6A 3RJ3A 1TQWA 1KRFA 3UD2A 4BOJA 1V7VA 3EJRA 4J5TA 3DPYB 3I3DA 2CFKA 3IAQA 3BVWA 1SO0A 4FNRA 4FNVA 2AHGA 4FXGB 2CWUA 2WY7A 4KFDA 2YIKA 4OK2A 1N7QA 4MMIA 4D4DA 3N9HA 3QPFA 3SXXA 1N4QB 2WGQA 4E1YA 3VD9A 4CJ1A 2WVXB 3QDEA 3BVVA 1UMPA 1H35A 4GL3A 1NS7A 2B39A 4ZH5A 5DHIA 2WOHA 2VN4A 2YX9A 1XWQA 3QFZA 3RENA 2XHNA 3S4BA 4GTTB 3W7WA 2FV1A 3WKHA 2WYIA 5C05A 3CV5A 3BVXA 1MMYA 1QALA 2WMKA 1AVKA 2ZQ0A 3E33B 3Q1NA 1J0MA 5JMDA 4TF4A 3BGAA 3T2PA 3M7EA 2D8LA 1TNOB 1G9GA 5IK0A 1D6YA 4AYPA 2XSGA 4FXKB 3EJUA 1HN1A 2F7OA 2ZZRA 4YDEB 1QAZA 1JZ2A 3HXFB 3QSPA 3DDGA 3X40A 3Q78B 1TQUA 2RI8A 2X03A 3RX7A 1HX9A 1HWWA 3KSLB 1IA6A 1HV6A 3ACTA 3K5TA 3EZ8A 3SX1A 1RWGA 3OBAA 1S63B 3CIHA 1SNZA 1H54A 5ILZA 4Q88A 1QBQB 2J5CA 5AGDA 4D4CA 1EKMA 4GTRB 2ZXQA 3A0OA 3KIIA 1LD8B 3T2QA 4D6FA 1L7KA 2BBCA 4DUXA 1L2AA 1GXMA 1V7WA 5DGRA 4QT9A 2BB6A 1ULVA 3NBJA 3X42A 1FCEA 4OZVA 5DHKA 1N9EA 3X3XA 1NSUA 1VD5A 1WZZA 2FUZA 3W7XA 3DX3A 1K72A 3X3ZA 2CIRA 1JCQB 1H3BA 2E24A 3QWTA 1F9DA 2F7QA 3WKFA 1TQTA 2KXRA 1GA2A 4L6XA 3SDVA 5FO8B 4D6EA 3DX0A 3PYBA 4BTYA 4DUVA 1W4NA 1TNZB 3Q7AB 1TU5A 3OB8A 1EGUA 2Y73A 1O79A 2WINB 3M7BA 3EUVB 3WUXA 2BT3A 2C10A 3D51A 3WVFA 2YFNA 1V5CA 1SIIA 4L9PB 1N94B 3CZJA 4WU0A 3M02A 2RI9A 2WW1A 1LTXB 3BVUA 3EJPA 2WIIB 1N1ZA 1NSXA 1H3CA 3BUIA 2ZL8A 3PGBA 1O1TB 1W3YA 3WKGA 1FO3A 4F13A 2CFGA 3MPHA 1DL2A 2WMJA 3QXFA 1NC5A 3HXDB 3QR8A 3HI7A 2QNOA 3PZ2B 1C3DA 1QAFA 1W6KA 1N7RA 3M73A 1PX3A 1WU4A 4DI5A 3T0DA 1KSDA 3IMHA 3VDBA 1HN0A 3TY1A 4D72A 4XUVA 3G4FA 3BUQA 3H2WA 3ECQA 3WIQA 3QG0A 4FNSA 2FUTA 3DSUB 1G87A 3E1F1 1X1IA 3RX8A 4BOKA 1GXNA 2E2TA 1UI8A 2WVXA 1D8DB 4OZWA 1KREA 1SQCA 4D8OA 3W7SA 3TF4A 4D6JA 1TXKA 2FYVA 4EV5A 5IL8A 2E22A 1NI1B 1HXKA 3DDFA 2JF4A 1N4PB 1JZ3A 1G6IA 4FJQA 1F1SA 1O6HA 1A2VA 3QFYA 3M77A 3VSNA 1F4HA 1JS4A 1WMNA 1N4RB 3LZ9A 1JYVA 3DSWB 2IEJB 4FNTA 2AFAA 2CG1A 4OJZA 1H12A 1JYWA 1N24A 1QQFA 4ZH1A 1KSIA 4C1SA 1NS2A 3E6UA 2OOVC 4GTMB 3X3YA 3OXUA 2WW2A 1V7XA 4EV2A 4LNVA 3D5SA 2WMFA 1W6GA 1LXMA 3M75A 3QT3A 3GT5A 2EACA 1YQ2A 1QAKA 2NVPA 3I3BA 4ONTA 1N21A 3P5PA 1NSVA 1RKYA 2EAEA 1JZ6A 3W7TA 1FO2A 2WW3A 3M76A 4EHMB 4D1JA 1K1XA 2XFGA 1AVLA 3HXBB 1JZ8A 2F1AA 1S64B 2WMHA 2XN2A 2Q1FA 2CQTA 5ILJA 2BRVX 5M7IA 3D5RA 3F59A 3T2OA 3C72B 3H7LA 4GAXA 2D73A 3U7VA 2F7PA 2GH4A 2CG0A 1HXAA 2P0VA 4NEIA 3ACSA 1IQYA 1RWCA 1O6RA 3BLBA 3ANJA 3SDQA 4D6HA 2PNCA 3DYOA 2EABA 4TXTA 5KBPA 5IK9A 5JPMB 5FO9B 1KKTA 2WYHA 2GZ6A 5ILIA 4GTQB 3DSSB 3GZKA 1H14A 2PN5A 1KFGA 5CZLA 3PZ3B 1XW2A 1NSMA 4D94A 2F6DA 4L0GA 4D6GA 1IVWA 4V1SA 2FV0A 1RQ5A 4WVAA 1O1SB 1IVUA 3EU5B 1PS3A 3D50A 1GSZA 3X17A 2PMVA 1WMPA 4FNPA 2G02A 3M7CA 5MEHA 1W6CA 3RX5A 3DCDA 4YCRA 3WIWA 4KKJA 3N0GA 4FUSA 2CFDA 2WCOA 1SPUA 4F10A 3X41A 3Q75B 2NOJA 3M72A 4WVBA 1K1YA 3HIGA 1X1JA 1OJOA 5FO7B 3DSXB 3WC3A 2CQSA 1L1YA 3N0FA 1FT1B 2XN1A 3KN4A 4CJ0A 3LOYA 2ZIRB 1CLCA 3SFXB 1YGAA 3KBTC 4UFCA 1GAHA 1RW9A 3VD4A 1JYXA 4ZRPA 3OEDA 3PZ1B 2H6GB 3LVTA 3T0AA 1JCRB 3G4DA 2XWBB 3HXEB 4LIXA 2OW7A 3AMOA 3DX4A 4CE7A 3E80A 1LF6A 3D52A 2WYNA 5ILHA 4KTRA 1JZ4A 1N1BA 1N22A 1LVNA 4BZFA 5IM1A 3EQAA 1QWNA 3DYPA 4MBGB 3S9VA 4KKIA 1OJNA 3VW5A 4D6IA 1UI7A 2XN0A 1MN0A 3BLCA 3WFAA 1DOGA 2I07B 4EL8A 4K3AA
chains in the Genus database with same CATH topology
1F1SA 1HMUA 3AFLA 2XHNA 5JMFA 3VSNA 1F4HA 1N7OA 3SEPA 1MMYA 1JYVA 2WMKA 4DUWA 4OJZA 2ZQ0A 3Q1NA 1J0MA 1JOVA 5JMDA 1JYWA 1HM2A 1UG9A 3BGAA 3T2PA 1NS2A 4AQ0A 1NSZA 1MMXA 1OJMA 3I3EA 1JYNA 2WW2A 2XSGA 3MUY1 2CIQA 2WW0A 1HN1A 1F9GA 2BRPA 2WMFA 1LXMA 1N7NA 3NJXA 1QAZA 1JZ2A 1YQ2A 2WVZA 3DYMA 1DP0A 2WDAA 1MMUA 3I3BA 2JKAA 2X03A 1NSVA 5E1QA 1JZ6A 1X1HA 3VDCA 2WW3A 1HV6A 1RWGA 3OBAA 1K1XA 3NNBA 4D6CA 1SNZA 2WMIB 1K1WA 1JZ8A 3NREA 2WMHA 1RWFA 2WMGA 2Q1FA 2ZXQA 3A0OA 2BRVX 3T2OA 3T2QA 4D6FA 1L7KA 1L7JA 1JZ7A 4DUXA 2WZSA 4BZGA 3NJVA 4MMHA 2D73A 1NSRA 4TTGA 1NKGA 1LOHA 1ULVA 4NEIA 3IAPA 1RWCA 4OZVA 3VSMA 1NSUA 1PX4A 4D6HA 2CIRA 2E24A 1C82A 2FUQA 3DYOA 1NS0A 3VDAA 3T0BA 4DUVA 4D6EA 3T08A 2WVYA 2BRWA 1NSMA 3OS7A 1LURA 3OB8A 1EGUA 1RWHA 4D6GA 5A1AA 4D6DA 4D71A 3WVFA 3MUZ1 3MWXA 1LXKA 1NSSA 2HTAA 3CZJA 3J7HA 1I8QA 2WW1A 1HMWA 3DCDA 1J0NA 1NSXA 2WCOA 3DECA 3VD7A 1LF9A 1Z45A 3VD5A 1W3YA 1HM3A 4F10A 4F13A 2HTBA 3VD3A 3E7JA 2WMJA 1X1JA 1K1YA 1OJOA 1MMZA 3A24A 1F4AA 3NFVA 1OJPA 3MV11 1N7RA 1YGAA 1PX3A 2JKPA 4RNLA 3T0DA 3IMHA 1RW9A 3VD4A 3VDBA 1HN0A 4J5TA 4D72A 3I3DA 3TY1A 1JYXA 4BZEA 3K25A 3IAQA 4OK4A 1SO0A 3ECQA 4BZHA 3T0AA 1RWAA 3BS6A 4FNVA 3E80A 2FUTA 1NS8A 1LF6A 3E1F1 1X1IA 1JZ4A 1JZ5A 4OK2A 3T09A 1N7QA 2CISA 4MMIA 2WVXA 1CB8A 4OZWA 4BZFA 1NS4A 2JKEA 1TXKA 1N7PA 4E1YA 4D6JA 3DYPA 2E22A 3VD9A 2WVXB 1OJNA 3MV01 4D6IA 2WMIA 1MN0A 3BLCA 1NS7A 3WFAA 1JZ3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1F1S A;  1HMU A;  3AFL A;  2XHN A;  5JMF A;  3VSN A;  1F4H A;  1N7O A;  3SEP A;  1MMY A;  1JYV A;  2WMK A;  4DUW A;  4OJZ A;  2ZQ0 A;  3Q1N A;  1J0M A;  1JOV A;  5JMD A;  1JYW A;  1HM2 A;  1UG9 A;  3BGA A;  3T2P A;  1NS2 A;  4AQ0 A;  1NSZ A;  1MMX A;  1OJM A;  3I3E A;  1JYN A;  2WW2 A;  2XSG A;  3MUY 1;  2CIQ A;  2WW0 A;  1HN1 A;  1F9G A;  2BRP A;  2WMF A;  1LXM A;  1N7N A;  3NJX A;  1QAZ A;  1JZ2 A;  1YQ2 A;  2WVZ A;  3DYM A;  1DP0 A;  2WDA A;  1MMU A;  3I3B A;  2JKA A;  2X03 A;  1NSV A;  5E1Q A;  1JZ6 A;  1X1H A;  3VDC A;  2WW3 A;  1HV6 A;  1RWG A;  3OBA A;  1K1X A;  3NNB A;  4D6C A;  1SNZ A;  2WMI B;  1K1W A;  1JZ8 A;  3NRE A;  2WMH A;  1RWF A;  2WMG A;  2Q1F A;  2ZXQ A;  3A0O A;  2BRV X;  3T2O A;  3T2Q A;  4D6F A;  1L7K A;  1L7J A;  1JZ7 A;  4DUX A;  2WZS A;  4BZG A;  3NJV A;  4MMH A;  2D73 A;  1NSR A;  4TTG A;  1NKG A;  1LOH A;  1ULV A;  4NEI A;  3IAP A;  1RWC A;  4OZV A;  3VSM A;  1NSU A;  1PX4 A;  4D6H A;  2CIR A;  2E24 A;  1C82 A;  2FUQ A;  3DYO A;  1NS0 A;  3VDA A;  3T0B A;  4DUV A;  4D6E A;  3T08 A;  2WVY A;  2BRW A;  1NSM A;  3OS7 A;  1LUR A;  3OB8 A;  1EGU A;  1RWH A;  4D6G A;  5A1A A;  4D6D A;  4D71 A;  3MUZ 1;  3MWX A;  1LXK A;  1NSS A;  2HTA A;  3CZJ A;  3J7H A;  1I8Q A;  2WW1 A;  1HMW A;  3DCD A;  1J0N A;  1NSX A;  2WCO A;  3DEC A;  3VD7 A;  1LF9 A;  1Z45 A;  3VD5 A;  1W3Y A;  1HM3 A;  4F10 A;  4F13 A;  2HTB A;  3VD3 A;  3E7J A;  2WMJ A;  1X1J A;  1K1Y A;  1OJO A;  1MMZ A;  3A24 A;  1F4A A;  3NFV A;  1OJP A;  3MV1 1;  1N7R A;  1YGA A;  1PX3 A;  2JKP A;  4RNL A;  3T0D A;  3IMH A;  1RW9 A;  3VD4 A;  3VDB A;  1HN0 A;  1JYX A;  4D72 A;  3I3D A;  4BZE A;  3K25 A;  3IAQ A;  4OK4 A;  1SO0 A;  3ECQ A;  4BZH A;  3T0A A;  1RWA A;  4FNV A;  3E80 A;  2FUT A;  1NS8 A;  1LF6 A;  3E1F 1;  1X1I A;  1JZ4 A;  1JZ5 A;  4OK2 A;  3T09 A;  1N7Q A;  2CIS A;  4MMI A;  2WVX A;  1CB8 A;  4OZW A;  4BZF A;  1NS4 A;  2JKE A;  1TXK A;  1N7P A;  4E1Y A;  4D6J A;  3DYP A;  2E22 A;  3VD9 A;  2WVX B;  1OJN A;  3MV0 1;  4D6I A;  2WMI A;  1MN0 A;  3WFA A;  1NS7 A;  1JZ3 A; 
#chains in the Genus database with same CATH topology
 3E32 B;  1IU7 A;  2XQW A;  4BTX A;  5JMF A;  2BED B;  1N7O A;  4D4A A;  4DUW A;  1WMO A;  1PU4 A;  5ILY A;  1HM2 A;  1UG9 A;  1AV4 A;  4K35 A;  4GTS B;  4AQ0 A;  2ZIS B;  1NSZ A;  1W6J A;  3EU8 A;  1HTY A;  3BUB A;  1OJM A;  3G6J B;  1JYN A;  4Q2B A;  3KBU C;  1F9G A;  3T33 A;  1H3A A;  1W7C A;  2CWT A;  3AMO B;  1TNY B;  3P2C A;  3QT9 A;  3H3K A;  5GZK A;  2CFW A;  4LNB B;  3DYM A;  1DP0 A;  1MMU A;  3HII A;  3QRY A;  3PQI A;  2OQE C;  1N20 A;  5IKA A;  2BB5 A;  1HZF A;  1D8E B;  1X81 B;  1QSJ A;  1QWU A;  1DYU A;  1TNB B;  2SQC A;  3SQC A;  1W2Z A;  1FP3 A;  3EJS A;  3RSY A;  1K1W A;  1W5Z A;  1N95 B;  4KFF A;  3WA3 A;  3NRE A;  3GLY A;  3PMM A;  1HCU A;  1O6Q A;  2WMG A;  1N4S B;  3K7X A;  2ALW A;  3A3V A;  1L7J A;  1R33 A;  1JZ7 A;  2WZS A;  3DX2 A;  4BZG A;  4GTP B;  4MMH A;  4AYR A;  2JG0 A;  1NKG A;  5CA3 A;  2F7R A;  3IAP A;  3VSM A;  1DCE B;  3KLS A;  1PX4 A;  4WVC A;  3D3I A;  1H36 A;  3P5R A;  4AYQ A;  5IL3 A;  5ILD A;  2A73 B;  4DLQ A;  1O5M B;  3Q7F B;  2WO0 A;  3T0U A;  2D5J A;  1IQX A;  3WIR A;  2DRO A;  5JPN B;  3T0B A;  1SIH A;  4DOE A;  2F1B A;  1X9D A;  2V8J A;  1OAC A;  2WVY A;  3EJT A;  1GHQ A;  2BRW A;  4Z4J A;  2V3N A;  3K11 A;  2YFO A;  5A1A A;  4D6D A;  4KFE A;  4JJJ A;  1FBO A;  2V8K A;  5EAU A;  2Y74 A;  3BVT A;  1LXK A;  3MUZ 1;  4FNQ A;  1N23 A;  1TN6 B;  1FT2 B;  2DRR A;  1I8Q A;  5IKH A;  1HMW A;  2RDY A;  2R2L B;  2AHF A;  3M74 A;  1SA4 B;  1WU6 A;  2EAD A;  2DRQ A;  3DEC A;  3SAE A;  1LF9 A;  4BZH A;  3DRA B;  1HM3 A;  2D1W A;  2HTB A;  3KQ4 A;  2ONG A;  3VD3 A;  1KWF A;  1MMZ A;  4BTW A;  1HXC A;  3NFV A;  1RJO A;  2F18 A;  3MV1 1;  3KSQ B;  3MI6 A;  4RNL A;  1KZO B;  2JKP A;  3VXD A;  1WU5 A;  3Q73 B;  3K25 A;  4BZE A;  1FAE A;  5FOB B;  4OK4 A;  1IVV A;  1D6U A;  3AFJ A;  2V3P A;  2B4F A;  1RWA A;  3BS6 A;  1NS8 A;  3M78 A;  1NL4 B;  1KZP B;  1V5D A;  2ZBL A;  2WY8 A;  5E2J A;  3T09 A;  1JZ5 A;  2CIS A;  5EAT A;  1CB8 A;  1NS4 A;  2JKE A;  1LD7 B;  1N7P A;  2E2V A;  1CEM A;  1UT9 A;  3MV0 1;  3SDR A;  1AGM A;  5CD2 A;  2WMI A;  4M76 A;  1IVX A;  1O7D D;  2H6F B;  3M71 A;  1FBW A;  1HMU A;  3AFL A;  3DX1 A;  3D4Z A;  3BUP A;  1TQS A;  3SEP A;  1FMI A;  1GXO A;  5GY3 A;  1QX1 A;  4ZG8 A;  1JOV A;  1TN8 B;  3M01 A;  4YDO B;  3SDU A;  4RNQ A;  2OKX A;  2CWV A;  1MMX A;  1AYX A;  3I3E A;  3W5N A;  3MUY 1;  2CIQ A;  1NXC A;  2WW0 A;  2BRP A;  1IS9 A;  3HXC B;  1N7N A;  3NJX A;  3CU7 A;  5EAS A;  1US1 A;  2H6I B;  2CFL A;  2WVZ A;  1MZC B;  1FPP B;  1IA7 A;  2WDA A;  3W7U A;  4DLO A;  3W5M A;  3S4C A;  2C11 A;  2JKA A;  3CZN A;  5E1Q A;  3RRS A;  3EJQ A;  5ILK A;  2Z07 A;  1X1H A;  3VDC A;  2VN7 A;  3M7L A;  1JRQ A;  1HXG A;  3PZ4 B;  1TF4 A;  3BUD A;  3NNB A;  4D6C A;  1G9J A;  2WMI B;  3E30 B;  3CZS A;  3E73 A;  2F0Y B;  2V8I A;  4KTP A;  3DSV B;  2H6H B;  4AYO A;  1D6Z A;  2W0Q A;  1RWF A;  2OW6 A;  3S4D A;  3NBB A;  4FNU A;  1GAI A;  2JJB A;  3E34 B;  3S4A A;  3NJV A;  3QXQ A;  1NSR A;  4TTG A;  1LOH A;  3SFY B;  1GLM A;  1R76 A;  2DRS A;  2XWJ B;  4ZRQ A;  2ONH A;  3D4Y A;  4MU9 A;  1F9O A;  3ALA A;  2A8Z A;  1C82 A;  1TN7 B;  2FUQ A;  1NS0 A;  3VDA A;  2RGK A;  3DST B;  2G0D A;  3T08 A;  3WA2 X;  5M7Y A;  3OS7 A;  1XWT A;  1LUR A;  2WOF A;  3SDT A;  3UD1 A;  2OQE A;  3Q79 B;  1H39 A;  1RWH A;  4GTV B;  1TNU B;  2GOX A;  3PYA A;  4D1I A;  4D71 A;  3MWX A;  2HTA A;  3ON6 A;  1NSS A;  1H37 A;  1KS8 A;  4DOD A;  4LNG B;  3M00 A;  3E37 B;  3J7H A;  1O1R B;  2E2U A;  4Z4L A;  1H13 A;  4GTO B;  5DGQ A;  3ANI A;  1J0N A;  1JCS B;  5KKB A;  2FBA A;  1N9A B;  1TQV A;  3VD7 A;  1Z45 A;  3VD5 A;  2OOV A;  1R34 A;  3E7J A;  3A24 A;  3ANK A;  3WKI A;  5GW7 A;  1KSC A;  1F4A A;  2KXS A;  4V1R A;  1SA5 B;  4D4B A;  1OJP A;  5IK6 A;  3RJ3 A;  1TQW A;  1KRF A;  3UD2 A;  4BOJ A;  1V7V A;  3EJR A;  4J5T A;  3DPY B;  3I3D A;  2CFK A;  3IAQ A;  3BVW A;  1SO0 A;  4FNR A;  4FNV A;  2AHG A;  4FXG B;  2CWU A;  2WY7 A;  4KFD A;  2YIK A;  4OK2 A;  1N7Q A;  4MMI A;  4D4D A;  3N9H A;  3QPF A;  3SXX A;  1N4Q B;  2WGQ A;  4E1Y A;  3VD9 A;  4CJ1 A;  2WVX B;  3QDE A;  3BVV A;  1UMP A;  1H35 A;  4GL3 A;  1NS7 A;  2B39 A;  4ZH5 A;  5DHI A;  2WOH A;  2VN4 A;  2YX9 A;  1XWQ A;  3QFZ A;  3REN A;  2XHN A;  3S4B A;  4GTT B;  3W7W A;  2FV1 A;  3WKH A;  2WYI A;  5C05 A;  3CV5 A;  3BVX A;  1MMY A;  1QAL A;  2WMK A;  1AVK A;  2ZQ0 A;  3E33 B;  3Q1N A;  1J0M A;  5JMD A;  4TF4 A;  3BGA A;  3T2P A;  3M7E A;  2D8L A;  1TNO B;  1G9G A;  5IK0 A;  1D6Y A;  4AYP A;  2XSG A;  4FXK B;  3EJU A;  1HN1 A;  2F7O A;  2ZZR A;  4YDE B;  1QAZ A;  1JZ2 A;  3HXF B;  3QSP A;  3DDG A;  3X40 A;  3Q78 B;  1TQU A;  2RI8 A;  2X03 A;  3RX7 A;  1HX9 A;  1HWW A;  3KSL B;  1IA6 A;  1HV6 A;  3ACT A;  3K5T A;  3EZ8 A;  3SX1 A;  1RWG A;  3OBA A;  1S63 B;  3CIH A;  1SNZ A;  1H54 A;  5ILZ A;  4Q88 A;  1QBQ B;  2J5C A;  5AGD A;  4D4C A;  1EKM A;  4GTR B;  2ZXQ A;  3A0O A;  3KII A;  1LD8 B;  3T2Q A;  4D6F A;  1L7K A;  2BBC A;  4DUX A;  1L2A A;  1GXM A;  1V7W A;  5DGR A;  4QT9 A;  2BB6 A;  1ULV A;  3NBJ A;  3X42 A;  1FCE A;  4OZV A;  5DHK A;  1N9E A;  3X3X A;  1NSU A;  1VD5 A;  1WZZ A;  2FUZ A;  3W7X A;  3DX3 A;  1K72 A;  3X3Z A;  2CIR A;  1JCQ B;  1H3B A;  2E24 A;  3QWT A;  1F9D A;  2F7Q A;  3WKF A;  1TQT A;  2KXR A;  1GA2 A;  4L6X A;  3SDV A;  5FO8 B;  4D6E A;  3DX0 A;  3PYB A;  4BTY A;  4DUV A;  1W4N A;  1TNZ B;  3Q7A B;  1TU5 A;  3OB8 A;  1EGU A;  2Y73 A;  1O79 A;  2WIN B;  3M7B A;  3EUV B;  3WUX A;  2BT3 A;  2C10 A;  3D51 A;  3WVF A;  2YFN A;  1V5C A;  1SII A;  4L9P B;  1N94 B;  3CZJ A;  4WU0 A;  3M02 A;  2RI9 A;  2WW1 A;  1LTX B;  3BVU A;  3EJP A;  2WII B;  1N1Z A;  1NSX A;  1H3C A;  3BUI A;  2ZL8 A;  3PGB A;  1O1T B;  1W3Y A;  3WKG A;  1FO3 A;  4F13 A;  2CFG A;  3MPH A;  1DL2 A;  2WMJ A;  3QXF A;  1NC5 A;  3HXD B;  3QR8 A;  3HI7 A;  2QNO A;  3PZ2 B;  1C3D A;  1QAF A;  1W6K A;  1N7R A;  3M73 A;  1PX3 A;  1WU4 A;  4DI5 A;  3T0D A;  1KSD A;  3IMH A;  3VDB A;  1HN0 A;  3TY1 A;  4D72 A;  4XUV A;  3G4F A;  3BUQ A;  3H2W A;  3ECQ A;  3WIQ A;  3QG0 A;  4FNS A;  2FUT A;  3DSU B;  1G87 A;  3E1F 1;  1X1I A;  3RX8 A;  4BOK A;  1GXN A;  2E2T A;  1UI8 A;  2WVX A;  1D8D B;  4OZW A;  1KRE A;  1SQC A;  4D8O A;  3W7S A;  3TF4 A;  4D6J A;  1TXK A;  2FYV A;  4EV5 A;  5IL8 A;  2E22 A;  1NI1 B;  1HXK A;  3DDF A;  2JF4 A;  1N4P B;  1JZ3 A;  1G6I A;  4FJQ A;  1F1S A;  1O6H A;  1A2V A;  3QFY A;  3M77 A;  3VSN A;  1F4H A;  1JS4 A;  1WMN A;  1N4R B;  3LZ9 A;  1JYV A;  3DSW B;  2IEJ B;  4FNT A;  2AFA A;  2CG1 A;  4OJZ A;  1H12 A;  1JYW A;  1N24 A;  1QQF A;  4ZH1 A;  1KSI A;  4C1S A;  1NS2 A;  3E6U A;  2OOV C;  4GTM B;  3X3Y A;  3OXU A;  2WW2 A;  1V7X A;  4EV2 A;  4LNV A;  3D5S A;  2WMF A;  1W6G A;  1LXM A;  3M75 A;  3QT3 A;  3GT5 A;  2EAC A;  1YQ2 A;  1QAK A;  2NVP A;  3I3B A;  4ONT A;  1N21 A;  3P5P A;  1NSV A;  1RKY A;  2EAE A;  1JZ6 A;  3W7T A;  1FO2 A;  2WW3 A;  3M76 A;  4EHM B;  4D1J A;  1K1X A;  2XFG A;  1AVL A;  3HXB B;  1JZ8 A;  2F1A A;  1S64 B;  2WMH A;  2XN2 A;  2Q1F A;  2CQT A;  5ILJ A;  2BRV X;  5M7I A;  3D5R A;  3F59 A;  3T2O A;  3C72 B;  3H7L A;  4GAX A;  2D73 A;  3U7V A;  2F7P A;  2GH4 A;  2CG0 A;  1HXA A;  2P0V A;  4NEI A;  3ACS A;  1IQY A;  1RWC A;  1O6R A;  3BLB A;  3ANJ A;  3SDQ A;  4D6H A;  2PNC A;  3DYO A;  2EAB A;  4TXT A;  5KBP A;  5IK9 A;  5JPM B;  5FO9 B;  1KKT A;  2WYH A;  2GZ6 A;  5ILI A;  4GTQ B;  3DSS B;  3GZK A;  1H14 A;  2PN5 A;  1KFG A;  5CZL A;  3PZ3 B;  1XW2 A;  1NSM A;  4D94 A;  2F6D A;  4L0G A;  4D6G A;  1IVW A;  4V1S A;  2FV0 A;  1RQ5 A;  4WVA A;  1O1S B;  1IVU A;  3EU5 B;  1PS3 A;  3D50 A;  1GSZ A;  3X17 A;  2PMV A;  1WMP A;  4FNP A;  2G02 A;  3M7C A;  5MEH A;  1W6C A;  3RX5 A;  3DCD A;  4YCR A;  3WIW A;  4KKJ A;  3N0G A;  4FUS A;  2CFD A;  2WCO A;  1SPU A;  4F10 A;  3X41 A;  3Q75 B;  2NOJ A;  3M72 A;  4WVB A;  1K1Y A;  3HIG A;  1X1J A;  1OJO A;  5FO7 B;  3DSX B;  3WC3 A;  2CQS A;  1L1Y A;  3N0F A;  1FT1 B;  2XN1 A;  3KN4 A;  4CJ0 A;  3LOY A;  2ZIR B;  1CLC A;  3SFX B;  1YGA A;  3KBT C;  4UFC A;  1GAH A;  1RW9 A;  3VD4 A;  1JYX A;  4ZRP A;  3OED A;  3PZ1 B;  2H6G B;  3LVT A;  3T0A A;  1JCR B;  3G4D A;  2XWB B;  3HXE B;  4LIX A;  2OW7 A;  3AMO A;  3DX4 A;  4CE7 A;  3E80 A;  1LF6 A;  3D52 A;  2WYN A;  5ILH A;  4KTR A;  1JZ4 A;  1N1B A;  1N22 A;  1LVN A;  4BZF A;  5IM1 A;  3EQA A;  1QWN A;  3DYP A;  4MBG B;  3S9V A;  4KKI A;  1OJN A;  3VW5 A;  4D6I A;  1UI7 A;  2XN0 A;  1MN0 A;  3BLC A;  3WFA A;  1DOG A;  2I07 B;  4EL8 A;  4K3A A; 
#chains in the Genus database with same CATH homology
 1F1S A;  1HMU A;  3AFL A;  2XHN A;  5JMF A;  3VSN A;  1F4H A;  1N7O A;  3SEP A;  1MMY A;  1JYV A;  2WMK A;  4DUW A;  4OJZ A;  2ZQ0 A;  3Q1N A;  1J0M A;  1JOV A;  5JMD A;  1JYW A;  1HM2 A;  1UG9 A;  3BGA A;  3T2P A;  1NS2 A;  4AQ0 A;  1NSZ A;  1MMX A;  1OJM A;  3I3E A;  1JYN A;  2WW2 A;  2XSG A;  3MUY 1;  2CIQ A;  2WW0 A;  1HN1 A;  1F9G A;  2BRP A;  2WMF A;  1LXM A;  1N7N A;  3NJX A;  1QAZ A;  1JZ2 A;  1YQ2 A;  2WVZ A;  3DYM A;  1DP0 A;  2WDA A;  1MMU A;  3I3B A;  2JKA A;  2X03 A;  1NSV A;  5E1Q A;  1JZ6 A;  1X1H A;  3VDC A;  2WW3 A;  1HV6 A;  1RWG A;  3OBA A;  1K1X A;  3NNB A;  4D6C A;  1SNZ A;  2WMI B;  1K1W A;  1JZ8 A;  3NRE A;  2WMH A;  1RWF A;  2WMG A;  2Q1F A;  2ZXQ A;  3A0O A;  2BRV X;  3T2O A;  3T2Q A;  4D6F A;  1L7K A;  1L7J A;  1JZ7 A;  4DUX A;  2WZS A;  4BZG A;  3NJV A;  4MMH A;  2D73 A;  1NSR A;  4TTG A;  1NKG A;  1LOH A;  1ULV A;  4NEI A;  3IAP A;  1RWC A;  4OZV A;  3VSM A;  1NSU A;  1PX4 A;  4D6H A;  2CIR A;  2E24 A;  1C82 A;  2FUQ A;  3DYO A;  1NS0 A;  3VDA A;  3T0B A;  4DUV A;  4D6E A;  3T08 A;  2WVY A;  2BRW A;  1NSM A;  3OS7 A;  1LUR A;  3OB8 A;  1EGU A;  1RWH A;  4D6G A;  5A1A A;  4D6D A;  4D71 A;  3WVF A;  3MUZ 1;  3MWX A;  1LXK A;  1NSS A;  2HTA A;  3CZJ A;  3J7H A;  1I8Q A;  2WW1 A;  1HMW A;  3DCD A;  1J0N A;  1NSX A;  2WCO A;  3DEC A;  3VD7 A;  1LF9 A;  1Z45 A;  3VD5 A;  1W3Y A;  1HM3 A;  4F10 A;  4F13 A;  2HTB A;  3VD3 A;  3E7J A;  2WMJ A;  1X1J A;  1K1Y A;  1OJO A;  1MMZ A;  3A24 A;  1F4A A;  3NFV A;  1OJP A;  3MV1 1;  1N7R A;  1YGA A;  1PX3 A;  2JKP A;  4RNL A;  3T0D A;  3IMH A;  1RW9 A;  3VD4 A;  3VDB A;  1HN0 A;  4J5T A;  4D72 A;  3I3D A;  3TY1 A;  1JYX A;  4BZE A;  3K25 A;  3IAQ A;  4OK4 A;  1SO0 A;  3ECQ A;  4BZH A;  3T0A A;  1RWA A;  3BS6 A;  4FNV A;  3E80 A;  2FUT A;  1NS8 A;  1LF6 A;  3E1F 1;  1X1I A;  1JZ4 A;  1JZ5 A;  4OK2 A;  3T09 A;  1N7Q A;  2CIS A;  4MMI A;  2WVX A;  1CB8 A;  4OZW A;  4BZF A;  1NS4 A;  2JKE A;  1TXK A;  1N7P A;  4E1Y A;  4D6J A;  3DYP A;  2E22 A;  3VD9 A;  2WVX B;  1OJN A;  3MV0 1;  4D6I A;  2WMI A;  1MN0 A;  3BLC A;  1NS7 A;  3WFA A;  1JZ3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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