1LOHA

Streptococcus pneumoniae hyaluronate lyase in complex with hexasaccharide hyaluronan substrate
Total Genus 258
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
258
sequence length
721
structure length
721
Chain Sequence
b'VKDTYTDRLDDWNGIIAGNQYYDSKNDQMAKLNQELEGKVADSLSSISSQADRIYLWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSMEWMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDPEHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGFYQDGSYIDHTNVAYTGAFGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAPLLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQSDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGFGLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTETDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFLGSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDSKKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYMLIPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVLKRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKL'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Hyaluronate Lyase
publication title Mechanism of hyaluronan degradation by Streptococcus pneumoniae hyaluronate lyase. Structures of complexes with the substrate.
pubmed doi rcsb
source organism Streptococcus pneumoniae
molecule tags Lyase
total genus 258
structure length 721
sequence length 721
ec nomenclature ec 4.2.2.1: Hyaluronate lyase.
pdb deposition date 2002-05-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02278 Lyase_8 Polysaccharide lyase family 8, super-sandwich domain
A PF02884 Lyase_8_C Polysaccharide lyase family 8, C-terminal beta-sandwich domain
A PF08124 Lyase_8_N Polysaccharide lyase family 8, N terminal alpha-helical domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.100 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Chondroitin AC/alginate lyase 1lohA02
2.60.220.10 Mainly Beta Sandwich Chondroitinase Ac; Chain A, domain 3 Polysaccharide lyase family 8-like, C-terminal 1lohA03
2.70.98.10 Mainly Beta Distorted Sandwich Beta-galactosidase; Chain A, domain 5 Beta-galactosidase; Chain A, domain 5 1lohA01
3MV01 1JZ7A 1K1XA 4FNVA 3VDBA 4OZVA 1LOHA 2WW2A 4D6CA 3AFLA 1NSVA 2WVXA 3NNBA 1ULVA 1JYXA 2JKPA 1HM3A 1OJNA 3SEPA 1EGUA 2X03A 2E22A 5A1AA 1C82A 3MV11 1F9GA 2HTBA 4OK2A 2JKAA 3MUZ1 1JZ3A 1MMYA 3VSNA 1L7JA 3T2PA 2WMIB 2WW0A 1NS2A 3T2QA 4D72A 3I3EA 1W3YA 3VD4A 1N7PA 1HN0A 4D6FA 1NKGA 1YGAA 3T0DA 3DYPA 2CIQA 1CB8A 4D6DA 1J0MA 3WFAA 1SO0A 3E1F1 2BRWA 4DUWA 4BZHA 1MMXA 1JZ4A 2FUQA 1JZ8A 1JYNA 3E80A 2WMIA 4D6JA 1RWCA 3IAQA 1RWGA 1HN1A 1RWAA 1PX4A 1NSZA 2XHNA 1LF9A 2D73A 2WZSA 4MMIA 1RWHA 3J7HA 2WW1A 3OBAA 1NSXA 1K1YA 5JMFA 2CIRA 3I3BA 3MUY1 5JMDA 1F1SA 1I8QA 3VSMA 4E1YA 1NS8A 3T08A 1JYWA 3NFVA 2BRPA 1L7KA 3NREA 3OS7A 1PX3A 1HM2A 1MMZA 3VDAA 4OJZA 1F4HA 3T2OA 2WDAA 1MMUA 1NSUA 2ZXQA 1LURA 3NJXA 1JZ2A 4MMHA 4RNLA 4D6IA 3Q1NA 1F4AA 1NS4A 2WW3A 4NEIA 1N7QA 2FUTA 2WVYA 1JZ6A 4DUVA 4BZGA 4OZWA 2WMHA 2WMGA 4F13A 2WMFA 1J0NA 1NS7A 2WVZA 3T09A 1QAZA 1JZ5A 3A0OA 1DP0A 4AQ0A 1RW9A 3T0BA 3BGAA 4D6HA 1X1HA 5E1QA 3ECQA 1NSRA 1N7NA 2HTAA 3DYMA 1K1WA 1HMWA 1LXKA 3DECA 2E24A 1OJOA 3A24A 2WMJA 2ZQ0A 4BZFA 2Q1FA 3VD5A 3DYOA 4D71A 3MWXA 1JYVA 1X1JA 1HMUA 3VDCA 1X1IA 1N7RA 1N7OA 1JOVA 1YQ2A 4D6GA 3K25A 1OJMA 4DUXA 1RWFA 2CISA 3VD3A 3VD7A 2BRVX 4TTGA 1SNZA 2WVXB 3OB8A 2JKEA 1NSMA 3VD9A 2WMKA 3NJVA 3T0AA 4D6EA 1NS0A 3I3DA 1HV6A 3E7JA 3DCDA 3IAPA 3CZJA 4BZEA 4OK4A 1Z45A 1UG9A 1NSSA 3IMHA 4F10A 1MN0A 1TXKA 2WCOA 1LF6A 1OJPA 2XSGA 1LXMA
chains in the Genus database with same CATH superfamily
2RGKA 4CJ1A 1R33A 3PGBA 4FNVA 3VDBA 4OZVA 2F1BA 1FBWA 1NSVA 2WVXA 3NNBA 1JYXA 3BS6A 1K72A 1QAFA 1S64B 3BVTA 1GXNA 1N4PB 1N4RB 2DRQA 3ANIA 1XWQA 2AFAA 3N0GA 3QFYA 1FP3A 4DLQA 1NS2A 1N9AB 5MEHA 3QDEA 4AYOA 2ONGA 2EACA 2CFWA 1IS9A 1HN0A 1SIIA 3ALAA 3BLBA 5GZKA 3EJSA 3KQ4A 3VW5A 5M7IA 3DYPA 3D3IA 3HXDB 2F7PA 4DI5A 3DRAB 1G6IA 3WFAA 4CE7A 1LTXB 4DUWA 3SX1A 3BVWA 2Y74A 2FUQA 3EJTA 5IKHA 3M01A 3E80A 4D6JA 3ON6A 4FXGB 2XQWA 1W2ZA 2ZL8A 3W7TA 4KKJA 3LZ9A 3M78A 2SQCA 2DRRA 4D4AA 4ZRPA 3J7HA 2ZBLA 5DGQA 1FAEA 3M74A 1QWNA 1K1YA 5JMFA 2CIRA 2F7OA 4DODA 2XN1A 1FT2B 4BOJA 3BUQA 3QXQA 5ILKA 1W4NA 4GTMB 1NS8A 1X9DA 3T08A 2BRPA 3NREA 1QALA 1PX3A 4K3AA 3DSUB 4YDEB 3T2OA 4LIXA 1MMUA 1HZFA 1QX1A 3NJXA 1JZ2A 4ZH1A 1KZPB 1QAKA 4RNLA 3K7XA 2FV1A 2H6IB 1IVVA 1F4AA 2OOVA 3PZ2B 3QXFA 2WVYA 2WINB 2YFNA 4D1IA 3BUIA 3HXEB 4Q2BA 1H3AA 3ANKA 3X40A 1N22A 3M76A 1NS7A 1TNUB 3DDFA 3E6UA 1QQFA 4FNPA 3QSPA 1HXGA 3S9VA 2OQEA 3QG0A 3DX3A 3T0BA 3BGAA 1H14A 4D6HA 2A8ZA 1PU4A 1K1WA 4K35A 1UI8A 1W6CA 1OJOA 1GXOA 1FPPB 2PNCA 4BOKA 2Q1FA 2WY8A 5JPMB 3W5NA 3DYOA 1JYVA 1IA6A 2CWTA 1HMUA 1N23A 2NVPA 3VDCA 1TF4A 3RRSA 3M77A 3LVTA 3D52A 1NL4B 2Z07A 2YIKA 2XWBB 5GY3A 1FO2A 2GH4A 3X41A 4MU9A 3VXDA 1TN8B 5IM1A 2WGQA 3WKHA 1KREA 4BTWA 2EABA 1SA5B 4TXTA 3DCDA 3IAPA 1DCEB 4LNGB 1IQXA 2FV0A 2PMVA 1Z45A 3IMHA 3X3ZA 5KKBA 4GTOB 1LD7B 3RX7A 4V1RA 2XN0A 3OXUA 1WMNA 1G87A 1SIHA 4GTVB 3W7WA 1LVNA 2PN5A 1TQVA 4MBGB 2WOFA 1O5MB 4D4BA 1TNYB 2JKPA 1HM3A 1OJNA 4WVBA 3WC3A 1EGUA 1FT1B 4V1SA 4D4DA 4DLOA 3TF4A 4YDOB 1F9OA 3Q7FB 5EATA 1F9GA 4OK2A 1KSDA 1MMYA 1L7JA 1HTYA 3DDGA 1R34A 4WVCA 1IVXA 2WMIB 3PZ3B 1DL2A 1IVUA 3M7EA 4D8OA 1MZCB 1N95B 3EU8A 4D6FA 3SFYB 1NI1B 1QSJA 2H6HB 4L9PB 2RDYA 3BUDA 1GSZA 5ILIA 3X42A 1NXCA 3F59A 1N20A 5AGDA 2CWUA 2OOVC 2BB6A 3E34B 2BRWA 2W0QA 1V5DA 2F18A 1JZ4A 1JZ8A 2WMIA 1TQWA 3QRYA 3IAQA 1RWGA 2RI8A 3DSWB 3EU5B 1JCRB 1D6UA 3H7LA 3WA3A 2VN7A 3S4DA 1D8DB 4GTQB 3ANJA 1US1A 3PYBA 4FUSA 2OQEC 1N94B 3HXBB 2YX9A 4KFEA 1SA4B 3OBAA 3AFJA 5E2JA 1NSXA 4AYPA 2QNOA 3I3BA 3QR8A 2V8IA 1O1TB 4FNUA 1H35A 1GA2A 5JMDA 2E2UA 2C10A 2GOXA 1I8QA 3PZ4B 3N0FA 3VSMA 3WIWA 4E1YA 3EUVB 2KXSA 1JYWA 1OACA 3DX1A 3OS7A 1C3DA 1HM2A 4OJZA 1WMPA 1H13A 1NSUA 3HXCB 3M73A 1LURA 3WVFA 1JS4A 4MMHA 5FOBB 1V5CA 4BTYA 5C05A 2WW3A 2JG0A 3HIIA 3KIIA 3LOYA 1FO3A 2F7QA 4DUVA 1GAHA 2BEDB 2WMGA 2F6DA 4F13A 1IQYA 2J5CA 1IU7A 2WMFA 1W6GA 4BTXA 2FYVA 1J0NA 2OW6A 2WVZA 1AGMA 1HXCA 3N9HA 4ZG8A 2BT3A 3D5RA 3WIQA 3M00A 3DPYB 3U7VA 3K11A 1EKMA 1O7DD 3PMMA 5DGRA 1NSRA 2HTAA 3X3XA 1N1BA 3E37B 4L0GA 3KBUC 4BZFA 3PYAA 1KS8A 5FO8B 1L2AA 5ILDA 4D71A 3BUPA 4KFFA 1IA7A 1S63B 3E32B 1X1IA 2RI9A 1GHQA 4GTTB 5DHIA 4C1SA 5KBPA 1N7OA 3P5PA 3QWTA 1JOVA 4D1JA 1TQSA 2CG1A 1V7XA 1H54A 3S4AA 4WU0A 3OB8A 2JKEA 1CLCA 3W7UA 4KFDA 1HV6A 3E7JA 2FUZA 1HWWA 3BVVA 4BZEA 2P0VA 3QT3A 3C72B 2WYNA 1UI7A 3CZNA 4F10A 1F9DA 2G02A 3M7LA 4LNVA 2XSGA 3EJPA 2BB5A 1JZ7A 1K1XA 2B4FA 4UFCA 3KSLB 3H2WA 4Q88A 3KBTC 3GLYA 2WW2A 3NBBA 4FNRA 2Y73A 1QBQB 3SEPA 3HI7A 2V3PA 1LD8B 2E22A 5M7YA 1C82A 4RNQA 3MV11 1JCSB 2DROA 2JKAA 3MUZ1 1JZ3A 4D4CA 3VSNA 3T2PA 1RKYA 1GAIA 1D8EB 3G6JB 4KKIA 1TQUA 1TU5A 5CA3A 3BUBA 1FBOA 1W3YA 3VD4A 1N7PA 1KSIA 4GAXA 1YGAA 1HX9A 3RENA 1HXKA 2A73B 2CIQA 1KZOB 4D6DA 3SDTA 1SO0A 1H39A 1MMXA 4AYQA 2EADA 4GL3A 3UD2A 1HN1A 1RWAA 3M72A 1PX4A 1NSZA 2C11A 3MPHA 1WU5A 2XHNA 2D73A 2WZSA 4MMIA 3MI6A 1RWHA 3G4FA 2CQSA 1RJOA 4ONTA 3EZ8A 2V8KA 1N21A 4WVAA 3ACTA 3T33A 1KKTA 1F1SA 3E30B 4J5TA 1KSCA 1DOGA 3DSSB 1DYUA 3NFVA 3QFZA 4DOEA 1AVLA 3D51A 1L7KA 2V8JA 4M76A 5DHKA 1H3BA 1MMZA 1N9EA 1H12A 2WDAA 2ZIRB 4AYRA 2WO0A 2ZXQA 1WU6A 5ILZA 1N24A 1WU4A 4D6IA 1AVKA 3OEDA 5JPNB 1NS4A 1FCEA 1VD5A 1N7QA 2FUTA 4NEIA 4EV5A 3Q75B 2VN4A 2R2LB 2GZ6A 4Z4JA 3WA2X 1SQCA 3RJ3A 3RX5A 3EJUA 2CWVA 4EL8A 3Q73B 2BBCA 4AQ0A 1UT9A 4FJQA 4FNTA 5IK0A 3GT5A 5ILHA 2JF4A 1X1HA 1W6KA 3ECQA 1N7NA 5FO7B 1HMWA 1N1ZA 3UD1A 2H6GB 2E2VA 3A24A 1O1SB 2WMJA 1V7VA 4GTSB 2ZQ0A 3E73A 1L1YA 1X1JA 4Z4LA 3CIHA 1XWTA 3Q7AB 1O6RA 1N7RA 5GW7A 2KXRA 1YQ2A 1KFGA 3KSQB 4DUXA 4CJ0A 2CISA 3HXFB 3W7XA 5FO9B 4D94A 2CFLA 1JCQB 3WUXA 2G0DA 3SDUA 3VD9A 1N4SB 1SPUA 4D6EA 1NS0A 2D1WA 3I3DA 3P5RA 2CG0A 3Q79B 4OK4A 1O6QA 1TNBB 2CFDA 3E33B 1D6ZA 1TXKA 3ACSA 3DSVB 2XN2A 2WCOA 3BVXA 1OJPA 4GTPB 3D50A 2CFKA 3RX8A 3WKGA 4FNSA 4KTRA 3MV01 2E2TA 1O1RB 2CQTA 2WOHA 3SDRA 1LOHA 2V3NA 3A3VA 3P2CA 4D6CA 3AFLA 1TQTA 2F1AA 4EHMB 2NOJA 2XFGA 5IL8A 1ULVA 1AV4A 1W5ZA 2X03A 2ZISB 5A1AA 3DSXB 4FNQA 2HTBA 1KWFA 3W5MA 5IK6A 2WW0A 3DX0A 1HXAA 3D4ZA 2AHFA 3PZ1B 3T2QA 4D72A 3I3EA 4TF4A 1D6YA 1WZZA 3SDQA 1NKGA 3T0DA 2ZZRA 1CB8A 3BVUA 3KN4A 5IK9A 1J0MA 2WYIA 3SXXA 2JJBA 3AMOB 3SFXB 3E1F1 2D8LA 1JRQA 2OKXA 4BZHA 5IL3A 2ALWA 4ZH5A 1JYNA 5EASA 1RWCA 5ILYA 2WY7A 1XW2A 3S4CA 4FXKB 3EJRA 1LF9A 2WW1A 2AHGA 5EAUA 4EV2A 1TN6B 1W7CA 3T0UA 5ILJA 4KTPA 2XWJB 5IKAA 3DX4A 3MUY1 1AYXA 1H3CA 1W6JA 2YFOA 2ONHA 3M7BA 3AMOA 2IEJB 3Q78B 1O6HA 5CD2A 1X81B 1UMPA 4JJJA 3H3KA 1TNZB 3DX2A 3VDAA 1F4HA 3NBJA 4GTRB 1N4QB 2WYHA 1R76A 1IVWA 3Q1NA 3M71A 3X17A 3M02A 2H6FB 1JZ6A 1A2VA 4BZGA 1GLMA 1O79A 4OZWA 2WMHA 3M75A 3EJQA 3GZKA 1G9JA 3G4DA 2F7RA 3T09A 1QAZA 1JZ5A 3A0OA 1H36A 1DP0A 1FMIA 1GXMA 1RW9A 4XUVA 3PQIA 3SDVA 5E1QA 1TNOB 2F0YB 3QPFA 3D5SA 1WMOA 2CFGA 3DYMA 1LXKA 3DECA 2E24A 3HIGA 2EAEA 3DSTB 3K5TA 3CZSA 1QWUA 2I07B 3MWXA 3VD5A 1HCUA 1G9GA 2B39A 3KLSA 4L6XA 3EQAA 3RSYA 4LNBB 2WIIB 3CU7A 4D6GA 3K25A 2DRSA 1OJMA 4YCRA 3SQCA 1RWFA 1H37A 3SAEA 1NC5A 3W7SA 3X3YA 3VD3A 3VD7A 2BRVX 4QT9A 3BLCA 4TTGA 3WKFA 1SNZA 2WVXB 2OW7A 3D4YA 1V7WA 1NSMA 5CZLA 2WMKA 3TY1A 3NJVA 1KRFA 1TN7B 3T0AA 3S4BA 3WIRA 2FBAA 3QT9A 3WKIA 3CZJA 2D5JA 4ZRQA 3CV5A 1CEMA 1UG9A 1NSSA 1PS3A 1MN0A 1LF6A 3M7CA 1RQ5A 1LXMA
chains in the Genus database with same CATH topology
3MV01 1JZ7A 1K1XA 4FNVA 3VDBA 4OZVA 1LOHA 2WW2A 4D6CA 3AFLA 1NSVA 2WVXA 3NNBA 1ULVA 1JYXA 2JKPA 1HM3A 1OJNA 3BS6A 3SEPA 1EGUA 2X03A 2E22A 5A1AA 1C82A 3MV11 1F9GA 2HTBA 4OK2A 2JKAA 3MUZ1 1JZ3A 1MMYA 3VSNA 1L7JA 3T2PA 2WMIB 2WW0A 1NS2A 3T2QA 4D72A 3I3EA 1W3YA 3VD4A 1N7PA 1HN0A 4D6FA 1NKGA 1YGAA 3T0DA 3DYPA 2CIQA 1CB8A 4D6DA 1J0MA 3WFAA 1SO0A 3E1F1 2BRWA 4DUWA 4BZHA 1MMXA 1JZ4A 2FUQA 1JZ8A 1JYNA 3E80A 2WMIA 4D6JA 1RWCA 3IAQA 1RWGA 1HN1A 1RWAA 1PX4A 1NSZA 2XHNA 1LF9A 2D73A 2WZSA 4MMIA 1RWHA 3J7HA 2WW1A 3OBAA 1NSXA 1K1YA 5JMFA 2CIRA 3I3BA 3MUY1 5JMDA 1F1SA 4J5TA 1I8QA 3VSMA 4E1YA 1NS8A 3T08A 1JYWA 3NFVA 2BRPA 1L7KA 3NREA 3OS7A 1PX3A 1HM2A 1MMZA 3VDAA 4OJZA 1F4HA 3T2OA 2WDAA 1MMUA 1NSUA 2ZXQA 1LURA 3NJXA 3WVFA 1JZ2A 4MMHA 4RNLA 4D6IA 3Q1NA 1F4AA 1NS4A 2WW3A 4NEIA 1N7QA 2FUTA 2WVYA 1JZ6A 4DUVA 4BZGA 4OZWA 2WMHA 2WMGA 4F13A 2WMFA 1J0NA 1NS7A 2WVZA 3T09A 1QAZA 1JZ5A 3A0OA 1DP0A 4AQ0A 1RW9A 3T0BA 3BGAA 4D6HA 1X1HA 5E1QA 3ECQA 1NSRA 1N7NA 2HTAA 3DYMA 1K1WA 1HMWA 1LXKA 3DECA 2E24A 1OJOA 3A24A 2WMJA 2ZQ0A 4BZFA 2Q1FA 3VD5A 3DYOA 4D71A 3MWXA 1JYVA 1X1JA 1HMUA 3VDCA 1X1IA 1N7RA 1N7OA 1JOVA 1YQ2A 4D6GA 3K25A 1OJMA 4DUXA 1RWFA 2CISA 3VD3A 3VD7A 2BRVX 3BLCA 4TTGA 1SNZA 2WVXB 3TY1A 3OB8A 2JKEA 1NSMA 3VD9A 2WMKA 3NJVA 3T0AA 4D6EA 1NS0A 3I3DA 1HV6A 3E7JA 3DCDA 3IAPA 3CZJA 4BZEA 4OK4A 1Z45A 1UG9A 1NSSA 3IMHA 4F10A 1MN0A 1TXKA 2WCOA 1LF6A 1OJPA 2XSGA 1LXMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3MV0 1;  1JZ7 A;  1K1X A;  4FNV A;  3VDB A;  4OZV A;  1LOH A;  2WW2 A;  4D6C A;  3AFL A;  1NSV A;  2WVX A;  3NNB A;  1ULV A;  1JYX A;  2JKP A;  1HM3 A;  1OJN A;  3SEP A;  1EGU A;  2X03 A;  2E22 A;  5A1A A;  1C82 A;  3MV1 1;  1F9G A;  2HTB A;  4OK2 A;  2JKA A;  3MUZ 1;  1JZ3 A;  1MMY A;  3VSN A;  1L7J A;  3T2P A;  2WMI B;  2WW0 A;  1NS2 A;  3T2Q A;  4D72 A;  3I3E A;  1W3Y A;  3VD4 A;  1N7P A;  1HN0 A;  4D6F A;  1NKG A;  1YGA A;  3T0D A;  3DYP A;  2CIQ A;  1CB8 A;  4D6D A;  1J0M A;  3WFA A;  1SO0 A;  3E1F 1;  2BRW A;  4DUW A;  4BZH A;  1MMX A;  1JZ4 A;  2FUQ A;  1JZ8 A;  1JYN A;  3E80 A;  2WMI A;  4D6J A;  1RWC A;  3IAQ A;  1RWG A;  1HN1 A;  1RWA A;  1PX4 A;  1NSZ A;  2XHN A;  1LF9 A;  2D73 A;  2WZS A;  4MMI A;  1RWH A;  3J7H A;  2WW1 A;  3OBA A;  1NSX A;  1K1Y A;  5JMF A;  2CIR A;  3I3B A;  3MUY 1;  5JMD A;  1F1S A;  1I8Q A;  3VSM A;  4E1Y A;  1NS8 A;  3T08 A;  1JYW A;  3NFV A;  2BRP A;  1L7K A;  3NRE A;  3OS7 A;  1PX3 A;  1HM2 A;  1MMZ A;  3VDA A;  4OJZ A;  1F4H A;  3T2O A;  2WDA A;  1MMU A;  1NSU A;  2ZXQ A;  1LUR A;  3NJX A;  1JZ2 A;  4MMH A;  4RNL A;  4D6I A;  3Q1N A;  1F4A A;  1NS4 A;  2WW3 A;  4NEI A;  1N7Q A;  2FUT A;  2WVY A;  1JZ6 A;  4DUV A;  4BZG A;  4OZW A;  2WMH A;  2WMG A;  4F13 A;  2WMF A;  1J0N A;  1NS7 A;  2WVZ A;  3T09 A;  1QAZ A;  1JZ5 A;  3A0O A;  1DP0 A;  4AQ0 A;  1RW9 A;  3T0B A;  3BGA A;  4D6H A;  1X1H A;  5E1Q A;  3ECQ A;  1NSR A;  1N7N A;  2HTA A;  3DYM A;  1K1W A;  1HMW A;  1LXK A;  3DEC A;  2E24 A;  1OJO A;  3A24 A;  2WMJ A;  2ZQ0 A;  4BZF A;  2Q1F A;  3VD5 A;  3DYO A;  4D71 A;  3MWX A;  1JYV A;  1X1J A;  1HMU A;  3VDC A;  1X1I A;  1N7R A;  1N7O A;  1JOV A;  1YQ2 A;  4D6G A;  3K25 A;  1OJM A;  4DUX A;  1RWF A;  2CIS A;  3VD3 A;  3VD7 A;  2BRV X;  4TTG A;  1SNZ A;  2WVX B;  3OB8 A;  2JKE A;  1NSM A;  3VD9 A;  2WMK A;  3NJV A;  3T0A A;  4D6E A;  1NS0 A;  3I3D A;  1HV6 A;  3E7J A;  3DCD A;  3IAP A;  3CZJ A;  4BZE A;  4OK4 A;  1Z45 A;  1UG9 A;  1NSS A;  3IMH A;  4F10 A;  1MN0 A;  1TXK A;  2WCO A;  1LF6 A;  1OJP A;  2XSG A;  1LXM A; 
#chains in the Genus database with same CATH topology
 2RGK A;  4CJ1 A;  1R33 A;  3PGB A;  4FNV A;  3VDB A;  4OZV A;  2F1B A;  1FBW A;  1NSV A;  2WVX A;  3NNB A;  1JYX A;  3BS6 A;  1K72 A;  1QAF A;  1S64 B;  3BVT A;  1GXN A;  1N4P B;  1N4R B;  2DRQ A;  3ANI A;  1XWQ A;  2AFA A;  3N0G A;  3QFY A;  1FP3 A;  4DLQ A;  1NS2 A;  1N9A B;  5MEH A;  3QDE A;  4AYO A;  2ONG A;  2EAC A;  2CFW A;  1IS9 A;  1HN0 A;  1SII A;  3ALA A;  3BLB A;  5GZK A;  3EJS A;  3KQ4 A;  3VW5 A;  5M7I A;  3DYP A;  3D3I A;  3HXD B;  2F7P A;  4DI5 A;  3DRA B;  1G6I A;  3WFA A;  4CE7 A;  1LTX B;  4DUW A;  3SX1 A;  3BVW A;  2Y74 A;  2FUQ A;  3EJT A;  5IKH A;  3M01 A;  3E80 A;  4D6J A;  3ON6 A;  4FXG B;  2XQW A;  1W2Z A;  2ZL8 A;  3W7T A;  4KKJ A;  3LZ9 A;  3M78 A;  2SQC A;  2DRR A;  4D4A A;  4ZRP A;  3J7H A;  2ZBL A;  5DGQ A;  1FAE A;  3M74 A;  1QWN A;  1K1Y A;  5JMF A;  2CIR A;  2F7O A;  4DOD A;  2XN1 A;  1FT2 B;  4BOJ A;  3BUQ A;  3QXQ A;  5ILK A;  1W4N A;  4GTM B;  1NS8 A;  1X9D A;  3T08 A;  2BRP A;  3NRE A;  1QAL A;  1PX3 A;  4K3A A;  3DSU B;  4YDE B;  3T2O A;  4LIX A;  1MMU A;  1HZF A;  1QX1 A;  3NJX A;  1JZ2 A;  4ZH1 A;  1KZP B;  1QAK A;  4RNL A;  3K7X A;  2FV1 A;  2H6I B;  1IVV A;  1F4A A;  2OOV A;  3PZ2 B;  3QXF A;  2WVY A;  2WIN B;  2YFN A;  4D1I A;  3BUI A;  3HXE B;  4Q2B A;  1H3A A;  3ANK A;  3X40 A;  1N22 A;  3M76 A;  1NS7 A;  1TNU B;  3DDF A;  3E6U A;  1QQF A;  4FNP A;  3QSP A;  1HXG A;  3S9V A;  2OQE A;  3QG0 A;  3DX3 A;  3T0B A;  3BGA A;  1H14 A;  4D6H A;  2A8Z A;  1PU4 A;  1K1W A;  4K35 A;  1UI8 A;  1W6C A;  1OJO A;  1GXO A;  1FPP B;  2PNC A;  4BOK A;  2Q1F A;  2WY8 A;  5JPM B;  3W5N A;  3DYO A;  1JYV A;  1IA6 A;  2CWT A;  1HMU A;  1N23 A;  2NVP A;  3VDC A;  1TF4 A;  3RRS A;  3M77 A;  3LVT A;  3D52 A;  1NL4 B;  2Z07 A;  2YIK A;  2XWB B;  5GY3 A;  1FO2 A;  2GH4 A;  3X41 A;  4MU9 A;  3VXD A;  1TN8 B;  5IM1 A;  2WGQ A;  3WKH A;  1KRE A;  4BTW A;  2EAB A;  1SA5 B;  4TXT A;  3DCD A;  3IAP A;  1DCE B;  4LNG B;  1IQX A;  2FV0 A;  2PMV A;  1Z45 A;  3IMH A;  3X3Z A;  5KKB A;  4GTO B;  1LD7 B;  3RX7 A;  4V1R A;  2XN0 A;  3OXU A;  1WMN A;  1G87 A;  1SIH A;  4GTV B;  3W7W A;  1LVN A;  2PN5 A;  1TQV A;  4MBG B;  2WOF A;  1O5M B;  4D4B A;  1TNY B;  2JKP A;  1HM3 A;  1OJN A;  4WVB A;  3WC3 A;  1EGU A;  1FT1 B;  4V1S A;  4D4D A;  4DLO A;  3TF4 A;  4YDO B;  1F9O A;  3Q7F B;  5EAT A;  1F9G A;  4OK2 A;  1KSD A;  1MMY A;  1L7J A;  1HTY A;  3DDG A;  1R34 A;  4WVC A;  1IVX A;  2WMI B;  3PZ3 B;  1DL2 A;  1IVU A;  3M7E A;  4D8O A;  1MZC B;  1N95 B;  3EU8 A;  4D6F A;  3SFY B;  1NI1 B;  1QSJ A;  2H6H B;  4L9P B;  2RDY A;  3BUD A;  1GSZ A;  5ILI A;  3X42 A;  1NXC A;  3F59 A;  1N20 A;  5AGD A;  2CWU A;  2OOV C;  2BB6 A;  3E34 B;  2BRW A;  2W0Q A;  1V5D A;  2F18 A;  1JZ4 A;  1JZ8 A;  2WMI A;  1TQW A;  3QRY A;  3IAQ A;  1RWG A;  2RI8 A;  3DSW B;  3EU5 B;  1JCR B;  1D6U A;  3H7L A;  3WA3 A;  2VN7 A;  3S4D A;  1D8D B;  4GTQ B;  3ANJ A;  1US1 A;  3PYB A;  4FUS A;  2OQE C;  1N94 B;  3HXB B;  2YX9 A;  4KFE A;  1SA4 B;  3OBA A;  3AFJ A;  5E2J A;  1NSX A;  4AYP A;  2QNO A;  3I3B A;  3QR8 A;  2V8I A;  1O1T B;  4FNU A;  1H35 A;  1GA2 A;  5JMD A;  2E2U A;  2C10 A;  2GOX A;  1I8Q A;  3PZ4 B;  3N0F A;  3VSM A;  3WIW A;  4E1Y A;  3EUV B;  2KXS A;  1JYW A;  1OAC A;  3DX1 A;  3OS7 A;  1C3D A;  1HM2 A;  4OJZ A;  1WMP A;  1H13 A;  1NSU A;  3HXC B;  3M73 A;  1LUR A;  3WVF A;  1JS4 A;  4MMH A;  5FOB B;  1V5C A;  4BTY A;  5C05 A;  2WW3 A;  2JG0 A;  3HII A;  3KII A;  3LOY A;  1FO3 A;  2F7Q A;  4DUV A;  1GAH A;  2BED B;  2WMG A;  2F6D A;  4F13 A;  1IQY A;  2J5C A;  1IU7 A;  2WMF A;  1W6G A;  4BTX A;  2FYV A;  1J0N A;  2OW6 A;  2WVZ A;  1AGM A;  1HXC A;  3N9H A;  4ZG8 A;  2BT3 A;  3D5R A;  3WIQ A;  3M00 A;  3DPY B;  3U7V A;  3K11 A;  1EKM A;  1O7D D;  3PMM A;  5DGR A;  1NSR A;  2HTA A;  3X3X A;  1N1B A;  3E37 B;  4L0G A;  3KBU C;  4BZF A;  3PYA A;  1KS8 A;  5FO8 B;  1L2A A;  5ILD A;  4D71 A;  3BUP A;  4KFF A;  1IA7 A;  1S63 B;  3E32 B;  1X1I A;  2RI9 A;  1GHQ A;  4GTT B;  5DHI A;  4C1S A;  5KBP A;  1N7O A;  3P5P A;  3QWT A;  1JOV A;  4D1J A;  1TQS A;  2CG1 A;  1V7X A;  1H54 A;  3S4A A;  4WU0 A;  3OB8 A;  2JKE A;  1CLC A;  3W7U A;  4KFD A;  1HV6 A;  3E7J A;  2FUZ A;  1HWW A;  3BVV A;  4BZE A;  2P0V A;  3QT3 A;  3C72 B;  2WYN A;  1UI7 A;  3CZN A;  4F10 A;  1F9D A;  2G02 A;  3M7L A;  4LNV A;  2XSG A;  3EJP A;  2BB5 A;  1JZ7 A;  1K1X A;  2B4F A;  4UFC A;  3KSL B;  3H2W A;  4Q88 A;  3KBT C;  3GLY A;  2WW2 A;  3NBB A;  4FNR A;  2Y73 A;  1QBQ B;  3SEP A;  3HI7 A;  2V3P A;  1LD8 B;  2E22 A;  5M7Y A;  1C82 A;  4RNQ A;  3MV1 1;  1JCS B;  2DRO A;  2JKA A;  3MUZ 1;  1JZ3 A;  4D4C A;  3VSN A;  3T2P A;  1RKY A;  1GAI A;  1D8E B;  3G6J B;  4KKI A;  1TQU A;  1TU5 A;  5CA3 A;  3BUB A;  1FBO A;  1W3Y A;  3VD4 A;  1N7P A;  1KSI A;  4GAX A;  1YGA A;  1HX9 A;  3REN A;  1HXK A;  2A73 B;  2CIQ A;  1KZO B;  4D6D A;  3SDT A;  1SO0 A;  1H39 A;  1MMX A;  4AYQ A;  2EAD A;  4GL3 A;  3UD2 A;  1HN1 A;  1RWA A;  3M72 A;  1PX4 A;  1NSZ A;  2C11 A;  3MPH A;  1WU5 A;  2XHN A;  2D73 A;  2WZS A;  4MMI A;  3MI6 A;  1RWH A;  3G4F A;  2CQS A;  1RJO A;  4ONT A;  3EZ8 A;  2V8K A;  1N21 A;  4WVA A;  3ACT A;  3T33 A;  1KKT A;  1F1S A;  3E30 B;  4J5T A;  1KSC A;  1DOG A;  3DSS B;  1DYU A;  3NFV A;  3QFZ A;  4DOE A;  1AVL A;  3D51 A;  1L7K A;  2V8J A;  4M76 A;  5DHK A;  1H3B A;  1MMZ A;  1N9E A;  1H12 A;  2WDA A;  2ZIR B;  4AYR A;  2WO0 A;  2ZXQ A;  1WU6 A;  5ILZ A;  1N24 A;  1WU4 A;  4D6I A;  1AVK A;  3OED A;  5JPN B;  1NS4 A;  1FCE A;  1VD5 A;  1N7Q A;  2FUT A;  4NEI A;  4EV5 A;  3Q75 B;  2VN4 A;  2R2L B;  2GZ6 A;  4Z4J A;  3WA2 X;  1SQC A;  3RJ3 A;  3RX5 A;  3EJU A;  2CWV A;  4EL8 A;  3Q73 B;  2BBC A;  4AQ0 A;  1UT9 A;  4FJQ A;  4FNT A;  5IK0 A;  3GT5 A;  5ILH A;  2JF4 A;  1X1H A;  1W6K A;  3ECQ A;  1N7N A;  5FO7 B;  1HMW A;  1N1Z A;  3UD1 A;  2H6G B;  2E2V A;  3A24 A;  1O1S B;  2WMJ A;  1V7V A;  4GTS B;  2ZQ0 A;  3E73 A;  1L1Y A;  1X1J A;  4Z4L A;  3CIH A;  1XWT A;  3Q7A B;  1O6R A;  1N7R A;  5GW7 A;  2KXR A;  1YQ2 A;  1KFG A;  3KSQ B;  4DUX A;  4CJ0 A;  2CIS A;  3HXF B;  3W7X A;  5FO9 B;  4D94 A;  2CFL A;  1JCQ B;  3WUX A;  2G0D A;  3SDU A;  3VD9 A;  1N4S B;  1SPU A;  4D6E A;  1NS0 A;  2D1W A;  3I3D A;  3P5R A;  2CG0 A;  3Q79 B;  4OK4 A;  1O6Q A;  1TNB B;  2CFD A;  3E33 B;  1D6Z A;  1TXK A;  3ACS A;  3DSV B;  2XN2 A;  2WCO A;  3BVX A;  1OJP A;  4GTP B;  3D50 A;  2CFK A;  3RX8 A;  3WKG A;  4FNS A;  4KTR A;  3MV0 1;  2E2T A;  1O1R B;  2CQT A;  2WOH A;  3SDR A;  1LOH A;  2V3N A;  3A3V A;  3P2C A;  4D6C A;  3AFL A;  1TQT A;  2F1A A;  4EHM B;  2NOJ A;  2XFG A;  5IL8 A;  1ULV A;  1AV4 A;  1W5Z A;  2X03 A;  2ZIS B;  5A1A A;  3DSX B;  4FNQ A;  2HTB A;  1KWF A;  3W5M A;  5IK6 A;  2WW0 A;  3DX0 A;  1HXA A;  3D4Z A;  2AHF A;  3PZ1 B;  3T2Q A;  4D72 A;  3I3E A;  4TF4 A;  1D6Y A;  1WZZ A;  3SDQ A;  1NKG A;  3T0D A;  2ZZR A;  1CB8 A;  3BVU A;  3KN4 A;  5IK9 A;  1J0M A;  2WYI A;  3SXX A;  2JJB A;  3AMO B;  3SFX B;  3E1F 1;  2D8L A;  1JRQ A;  2OKX A;  4BZH A;  5IL3 A;  2ALW A;  4ZH5 A;  1JYN A;  5EAS A;  1RWC A;  5ILY A;  2WY7 A;  1XW2 A;  3S4C A;  4FXK B;  3EJR A;  1LF9 A;  2WW1 A;  2AHG A;  5EAU A;  4EV2 A;  1TN6 B;  1W7C A;  3T0U A;  5ILJ A;  4KTP A;  2XWJ B;  5IKA A;  3DX4 A;  3MUY 1;  1AYX A;  1H3C A;  1W6J A;  2YFO A;  2ONH A;  3M7B A;  3AMO A;  2IEJ B;  3Q78 B;  1O6H A;  5CD2 A;  1X81 B;  1UMP A;  4JJJ A;  3H3K A;  1TNZ B;  3DX2 A;  3VDA A;  1F4H A;  3NBJ A;  4GTR B;  1N4Q B;  2WYH A;  1R76 A;  1IVW A;  3Q1N A;  3M71 A;  3X17 A;  3M02 A;  2H6F B;  1JZ6 A;  1A2V A;  4BZG A;  1GLM A;  1O79 A;  4OZW A;  2WMH A;  3M75 A;  3EJQ A;  3GZK A;  1G9J A;  3G4D A;  2F7R A;  3T09 A;  1QAZ A;  1JZ5 A;  3A0O A;  1H36 A;  1DP0 A;  1FMI A;  1GXM A;  1RW9 A;  4XUV A;  3PQI A;  3SDV A;  5E1Q A;  1TNO B;  2F0Y B;  3QPF A;  3D5S A;  1WMO A;  2CFG A;  3DYM A;  1LXK A;  3DEC A;  2E24 A;  3HIG A;  2EAE A;  3DST B;  3K5T A;  3CZS A;  1QWU A;  2I07 B;  3MWX A;  3VD5 A;  1HCU A;  1G9G A;  2B39 A;  3KLS A;  4L6X A;  3EQA A;  3RSY A;  4LNB B;  2WII B;  3CU7 A;  4D6G A;  3K25 A;  2DRS A;  1OJM A;  4YCR A;  3SQC A;  1RWF A;  1H37 A;  3SAE A;  1NC5 A;  3W7S A;  3X3Y A;  3VD3 A;  3VD7 A;  2BRV X;  4QT9 A;  3BLC A;  4TTG A;  3WKF A;  1SNZ A;  2WVX B;  2OW7 A;  3D4Y A;  1V7W A;  1NSM A;  5CZL A;  2WMK A;  3TY1 A;  3NJV A;  1KRF A;  1TN7 B;  3T0A A;  3S4B A;  3WIR A;  2FBA A;  3QT9 A;  3WKI A;  3CZJ A;  2D5J A;  4ZRQ A;  3CV5 A;  1CEM A;  1UG9 A;  1NSS A;  1PS3 A;  1MN0 A;  1LF6 A;  3M7C A;  1RQ5 A;  1LXM A; 
#chains in the Genus database with same CATH homology
 3MV0 1;  1JZ7 A;  1K1X A;  4FNV A;  3VDB A;  4OZV A;  1LOH A;  2WW2 A;  4D6C A;  3AFL A;  1NSV A;  2WVX A;  3NNB A;  1ULV A;  1JYX A;  2JKP A;  1HM3 A;  1OJN A;  3BS6 A;  3SEP A;  1EGU A;  2X03 A;  2E22 A;  5A1A A;  1C82 A;  3MV1 1;  1F9G A;  2HTB A;  4OK2 A;  2JKA A;  3MUZ 1;  1JZ3 A;  1MMY A;  3VSN A;  1L7J A;  3T2P A;  2WMI B;  2WW0 A;  1NS2 A;  3T2Q A;  4D72 A;  3I3E A;  1W3Y A;  3VD4 A;  1N7P A;  1HN0 A;  4D6F A;  1NKG A;  1YGA A;  3T0D A;  3DYP A;  2CIQ A;  1CB8 A;  4D6D A;  1J0M A;  3WFA A;  1SO0 A;  3E1F 1;  2BRW A;  4DUW A;  4BZH A;  1MMX A;  1JZ4 A;  2FUQ A;  1JZ8 A;  1JYN A;  3E80 A;  2WMI A;  4D6J A;  1RWC A;  3IAQ A;  1RWG A;  1HN1 A;  1RWA A;  1PX4 A;  1NSZ A;  2XHN A;  1LF9 A;  2D73 A;  2WZS A;  4MMI A;  1RWH A;  3J7H A;  2WW1 A;  3OBA A;  1NSX A;  1K1Y A;  5JMF A;  2CIR A;  3I3B A;  3MUY 1;  5JMD A;  1F1S A;  4J5T A;  1I8Q A;  3VSM A;  4E1Y A;  1NS8 A;  3T08 A;  1JYW A;  3NFV A;  2BRP A;  1L7K A;  3NRE A;  3OS7 A;  1PX3 A;  1HM2 A;  1MMZ A;  3VDA A;  4OJZ A;  1F4H A;  3T2O A;  2WDA A;  1MMU A;  1NSU A;  2ZXQ A;  1LUR A;  3NJX A;  3WVF A;  1JZ2 A;  4MMH A;  4RNL A;  4D6I A;  3Q1N A;  1F4A A;  1NS4 A;  2WW3 A;  4NEI A;  1N7Q A;  2FUT A;  2WVY A;  1JZ6 A;  4DUV A;  4BZG A;  4OZW A;  2WMH A;  2WMG A;  4F13 A;  2WMF A;  1J0N A;  1NS7 A;  2WVZ A;  3T09 A;  1QAZ A;  1JZ5 A;  3A0O A;  1DP0 A;  4AQ0 A;  1RW9 A;  3T0B A;  3BGA A;  4D6H A;  1X1H A;  5E1Q A;  3ECQ A;  1NSR A;  1N7N A;  2HTA A;  3DYM A;  1K1W A;  1HMW A;  1LXK A;  3DEC A;  2E24 A;  1OJO A;  3A24 A;  2WMJ A;  2ZQ0 A;  4BZF A;  2Q1F A;  3VD5 A;  3DYO A;  4D71 A;  3MWX A;  1JYV A;  1X1J A;  1HMU A;  3VDC A;  1X1I A;  1N7R A;  1N7O A;  1JOV A;  1YQ2 A;  4D6G A;  3K25 A;  1OJM A;  4DUX A;  1RWF A;  2CIS A;  3VD3 A;  3VD7 A;  2BRV X;  3BLC A;  4TTG A;  1SNZ A;  2WVX B;  3TY1 A;  3OB8 A;  2JKE A;  1NSM A;  3VD9 A;  2WMK A;  3NJV A;  3T0A A;  4D6E A;  1NS0 A;  3I3D A;  1HV6 A;  3E7J A;  3DCD A;  3IAP A;  3CZJ A;  4BZE A;  4OK4 A;  1Z45 A;  1UG9 A;  1NSS A;  3IMH A;  4F10 A;  1MN0 A;  1TXK A;  2WCO A;  1LF6 A;  1OJP A;  2XSG A;  1LXM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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