1LW3A

Crystal structure of myotubularin-related protein 2 complexed with phosphate
Total Genus 181
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
181
sequence length
513
structure length
513
Chain Sequence
EEPPLLPGENIKDMAKDVTYICPFTGAVRGTLTVTNYRLYFKSMERDPPFVLDASLGVINRVEKIGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPLFAFEYKEVFPENGWKLYDPLLEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPNIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHSSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFTNPLYGSYSNHVLYPVASMRHLELWVGYYIRWNPR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal Structure of a Phosphoinositide Phosphatase, MTMR2: Insights into Myotubular Myopathy and Charcot-Marie-Tooth Syndrome
pubmed doi rcsb
molecule keywords Myotubularin-related protein 2
molecule tags Hydrolase
source organism Homo sapiens
total genus 181
structure length 513
sequence length 513
ec nomenclature ec 3.1.3.64: Phosphatidylinositol-3-phosphatase.
pdb deposition date 2002-05-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02893 GRAM GRAM domain
A PF06602 Myotub-related Myotubularin-like phosphatase domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 1lw3A01
2LYDA 4B6HA 4XWXA 1XX0A 3PVUA 2X18A 1MK9B 2GJYA 3PSCA 1MPHA 2COCA 2NMBA 2VRWB 2DKPA 4CHMA 2YT0A 4A6HA 1QQGA 2KGXB 5KQ1A 5J3TA 4YONA 1KZGA 2D9ZA 4NSWA 1V5PA 2D9WA 3SUZA 1UPRA 3V5WA 3CIKA 2YVCA 4A6KA 1MKEA 5D3XA 2MDXA 4CHJA 1P5TA 1E5WA 2GS0A 5DIFB 2W2WA 4NY0A 2ELAA 4KAXB 3VIAA 3U7DA 4WJ7A 1PMSA 1DDVA 5DI9B 3LJUX 1V5UA 3F0WA 3AU4A 2HE7A 2N0YA 3UZTA 3PG7A 2M38A 3SYXA 2MWNB 2K2UA 1I2HA 2QKLA 4MT7A 1U5FA 1WVHA 2JP2A 1K5GB 2COAA 4GXBA 2DX1A 1X05A 1FGZA 3ULCA 1EAZA 1EGXA 1FHWA 2D4QA 2HTHB 1OMWA 2Z0QA 4EJNA 1NU2A 2LOXA 1J19A 2RUKB 3KSYA 4KHOA 1V61A 5HE3A 1H4RA 3SV1A 3WYFB 2Y8GA 1FHOA 1TQZA 2M14A 3X23A 5GOWB 2D2QA 1X86A 3FEHA 3N7CA 2H7EA 1ISNA 1WGQA 2DHKA 3TVVA 2EC1A 4A6FA 5JP4A 4K17A 1PLSA 4MY6A 1V88A 2P0HA 5DHFB 4A5KA 2R09A 3KRXA 2EJ8A 4HAZB 1EF1A 4HB3B 2XQNM 4HATB 4TYZA 3PP2A 3PVWA 4DX90 5DH9B 1WG7A 2P8VA 2D9YA 5C79A 1QC6A 2KUPA 1V5MA 1ZC3B 4IFSA 2EMSA 3ULBA 2D10A 5DHAB 5HE0A 1GC7A 1I7AA 4DXAB 2V76A 4K81A 1XKEA 3HW2B 4A6FB 1TXDA 2IFSA 2RLOA 5J3YA 2LG1A 5EFXA 1U5EA 4HAXB 1Q67A 2Z0PA 4HAUB 4GN1A 1BAKA 3MPXA 3AU5A 2YS5A 1M7RA 4CYEA 3WA0A 2I1JA 5C5BA 1W1GA 4KHBB 5FI1A 3NSUA 3D8FA 3SNHA 5LOPB 2CAYA 1TJ6A 2K2JA 3HQCA 3QBVB 2KCJA 3QWMA 4YL8A 3KRWA 1NI2A 4F7UP 1GG3A 2Y7BA 2Y8FA 1WI1A 4HDOA 1MK7B 4IAPA 5FI0A 3TCAA 3ML4A 2ROVA 2W2XD 5C5BB 3RCPA 5L81A 1BTNA 1U2BA 1IRSA 1NTYA 1W1HA 4F7HA 2RGNB 5CLQB 4ZRKA 1V89A 4DX8A 3ODOA 1LB1A 4F7GA 4EMOA 2ZPYA 2I1KA 2YS1A 2VSZA 1RJ2A 4KVGB 1U27A 4DBBA 1P6SA 1DDWA 2J59M 1XCGA 1MIXA 2LULA 3GYOA 1J0WA 1RRPB 4PQ0A 1DDMA 4HB2B 4GMXB 2EMTA 1ZVRA 5KQ4A 1LW3A 3BJIA 3VOQA 2N23A 5LONB 3T06A 1U5DA 3FSSA 1SHCA 4KHAA 5CLLB 1FAOA 1AQCA 1OY2A 1NTVA 5D27A 2GCLA 3G9WA 3KZ1A 3M1IB 1X1GA 3DXDA 4BBKA 1UEFA 1FHXA 1M7EA 2I5CA 1N3HA 2RSGA 1UNRA 3OANA 1X11A 1FOEA 2P0FA 3AJ4A 1Y5OA 4PNKA 4HB4B 3KY9A 2D9VA 3HK0A 3DXEA 5C6RA 1B55A 2J0MA 3PEGA 2ADZA 2W2XC 4HAVB 5D3VA 3F5RA 2YF0A 3A8PA 2E2XA 3GYPA 2DX5A 1X1FA 1U5GA 2ELBA 2OTXA 2AEHA 1SGHA 3CXBB 3A98B 2J0KA 1DROA 5D3WA 3TW1A 5JLJB 2Z0OA 4K2PA 4C0AA 5JHHA 1FGYA 1UNPA 4HDQA 3O96A 1MIZB 1XR0B 2Q13A 3BINA 1UPQA 2PZ1A 1BWNA 4HHVA 3U8ZA 3PZDA 2G35A 4ZRIA 4GMVA 2QKMA 4MK0A 2DYNA 4D0NB 1BTKA 4TKNA 3TO1A 2LOZA 3SO6A 2AL6A 2VKIA 3P7ZA 4HB0B 1U29A 2YT1A 4WVFB 2CRFA 3IVFA 4L6EA 4EKUA 2RNRB 5J3QA 1PFJA 2GCJA 2FJLA 1H10A 1DBHA 1Z87A 4Y94A 2K00A 2DA0A 2DFKA 1K5DB 3ODXA 2I5FA 2J0JA 2COFA 5HE2A 1OQNA 4ZRJA 1ZC4B 2IYBA 2YSZA 2DHIA 1ZM0A 1MAIA 1FB8A 2DTCA 3PVLA 1WGUA 2UZRA 5JHGA 2DHJA 1KZ7A 1EVHA 2DYQA 5HE1A 1WJMA 2P0DA 5KCVA 4HAWB 3A8QA 2YS3A 3DXCA 3ZDTA 3ZVRA 2YRYA 1ZSQA 3D8DA 2H7DA 4GPTB 2L1CA 2ROZB 2DLWA 3QIJA 1XD4A 1AWEA 4Z2NA 1WJ1A 2DN6A 2OQBA 2RVBB 4IOYX 2NZ8B 4HAYB 2UZSA 4WSFA 3MDBC 4P7IA 4Z2MB 2CY5A 3ODWA 4GZUA 1UNQA 1W1DA 1XODA 2R0DA 5D3YA 5C16A 4H8SA 2D9XA 2D11A 3FM8C 2MKRA 1P3RA 1DYNA 1KI1B 2CY4A 2MFQA 1Y19B 2L2IA 3P6AA 3D8EA 2DKQA 2CODA 2LKOA 2UVMA 4K2OA 1GC6A 2BCJA 3TFMA
chains in the Genus database with same CATH superfamily
2LYDA 4B6HA 4QJ4B 4XWXA 1XX0A 3PVUA 2X18A 1MK9B 2GJYA 2NBVA 2ZKMX 3PSCA 1MPHA 2COCA 2NMBA 3U12A 3HIEA 2VRWB 2DKPA 4CHMA 2YT0A 4A6HA 1QQGA 2KGXB 5KQ1A 5J3TA 4YONA 1KZGA 2D9ZA 4NSWA 1V5PA 2D9WA 2Z59A 3SUZA 1T77A 1UPRA 3V5WA 3CIKA 2YVCA 4A6KA 1MKEA 5D3XA 2MDXA 4CHJA 1P5TA 1E5WA 2GS0A 5DIFB 2W2WA 4NY0A 2ELAA 4KAXB 3VIAA 3U7DA 4WJ7A 4QXAB 1PMSA 2KUQA 1DDVA 5DI9B 3LJUX 1V5UA 3F0WA 3AU4A 4GNKB 2HE7A 2N0YA 3UZTA 3PG7A 2M38A 3SYXA 4DIXA 5IRSA 2KR0A 2FJUB 2K2UA 2MWNB 1I2HA 2QKLA 4MT7A 1U5FA 1WVHA 2JP2A 1K5GB 1MI1A 2COAA 4GXBA 2DX1A 1X05A 1FGZA 3ULCA 3HSAA 1EAZA 1EGXA 1FHWA 2D4QA 2HTHB 1OMWA 2Z0QA 4EJNA 1NU2A 2LOXA 1J19A 2RUKB 3KSYA 4KHOA 4CSQA 1V61A 5HE3A 1H4RA 3SV1A 3WYFB 2Y8GA 1FHOA 1TQZA 2M14A 2K8EA 3X23A 5GOWB 2D2QA 1X86A 3FEHA 3N7CA 2H7EA 2Z4DA 1ISNA 1WGQA 2DHKA 3TVVA 2EC1A 4A6FA 5JP4A 4K17A 1PLSA 4MY6A 1V88A 2P0HA 5DHFB 4A5KA 2R09A 3KRXA 2EJ8A 4HAZB 1EF1A 4HB3B 2XQNM 4HATB 4TYZA 3PP2A 3PVWA 4DX90 5DH9B 1WG7A 2P8VA 2D9YA 5C79A 3NW8A 1QC6A 2KUPA 1V5MA 1ZC3B 4IFSA 2EMSA 3ULBA 2D10A 5DHAB 5HE0A 1GC7A 1I7AA 4DXAB 2V76A 4K81A 1XKEA 3HW2B 4A6FB 1TXDA 2IFSA 2RLOA 4D6WA 5J3YA 2LG1A 5EFXA 2RRFA 3B77A 1U5EA 4HAXB 1Q67A 2Z0PA 4HAUB 4GN1A 1BAKA 3MPXA 3AU5A 2YS5A 1M7RA 4CYEA 5LG4B 3WA0A 2I1JA 5C5BA 1W1GA 4KHBB 5FI1A 3NSUA 3D8FA 3SNHA 5LOPB 2CAYA 1TJ6A 4L1RA 2K2JA 3HQCA 3QBVB 2KCJA 3QWMA 4YL8A 3KRWA 1NI2A 4F7UP 1GG3A 2Y7BA 2Y8FA 3OHMB 1WI1A 4HDOA 1MK7B 4IAPA 5FI0A 3TCAA 3ML4A 2ROVA 2W2XD 2K49A 5C5BB 3RCPA 5I2SA 5L81A 1BTNA 1U2BA 1IRSA 3NWDA 1NTYA 1W1HA 4F7HA 2RGNB 5CLQB 4ZRKA 1V89A 4DX8A 3ODOA 1LB1A 4F7GA 4EMOA 2ZPYA 2I1KA 2YS1A 2VSZA 1RJ2A 4KVGB 1U27A 4DBBA 1P6SA 1DDWA 2J59M 1XCGA 1MIXA 2LULA 3GYOA 1J0WA 1RRPB 4PQ0A 1DDMA 4HB2B 4GMXB 2EMTA 1ZVRA 5KQ4A 1LW3A 3BJIA 3VOQA 2N23A 5LONB 3T06A 1U5DA 3FSSA 1SHCA 4KHAA 5CLLB 1FAOA 1AQCA 1OY2A 1ZYIA 1NTVA 3A58A 5D27A 2GCLA 3G9WA 3KZ1A 3M1IB 1X1GA 3DXDA 5M4YB 4BBKA 1UEFA 1FHXA 1M7EA 2I5CA 1N3HA 2RSGA 1UNRA 3OANA 1X11A 1FOEA 2P0FA 3AJ4A 1Y5OA 4PNKA 4HB4B 3KY9A 2D9VA 3HK0A 4HSIA 3DXEA 5C6RA 1B55A 2J0MA 3PEGA 2ADZA 2W2XC 2KIGA 4HAVB 5D3VA 4KHBA 3F5RA 2YF0A 3A8PA 2E2XA 3GYPA 2DX5A 1X1FA 1U5GA 2ELBA 2OTXA 2AEHA 1SGHA 3CXBB 4QJ3B 3A98B 2J0KA 1DROA 4OT1A 5D3WA 3TW1A 5JLJB 5I2MA 2Z0OA 4K2PA 4C0AA 5JHHA 1FGYA 1UNPA 4HDQA 3O96A 1MIZB 1XR0B 2Q13A 3BINA 2Z14A 1UPQA 2PZ1A 1BWNA 4HHVA 3U8ZA 3PZDA 2G35A 4ZRIA 4QJ5B 4GMVA 2QKMA 4MK0A 2DYNA 4D0NB 1BTKA 4TKNA 3TO1A 2LOZA 3SO6A 2AL6A 2YT2A 2VKIA 3P7ZA 4HB0B 1U29A 2YT1A 4WVFB 2CRFA 3IVFA 4L6EA 4EKUA 2RNRB 5J3QA 1PFJA 2GCJA 2FJLA 1H10A 1DBHA 1Z87A 4GOUA 4Y94A 2K00A 2DA0A 2DFKA 1K5DB 2Z13A 3ODXA 2I5FA 2J0JA 2COFA 5HE2A 1OQNA 4ZRJA 1ZC4B 2IYBA 2YSZA 2DHIA 1ZM0A 1MAIA 1FB8A 2DTCA 3PVLA 1WGUA 2UZRA 5JHGA 2DHJA 3NWAA 1KZ7A 1EVHA 2DYQA 5HE1A 1WJMA 2P0DA 5KCVA 4HAWB 3A8QA 4OSNA 2YS3A 3DXCA 3ZDTA 2GUMA 3ZVRA 2YRYA 1ZSQA 3D8DA 2H7DA 4GPTB 2L1CA 2ROZB 2DLWA 3QIJA 2R2YA 1XD4A 1AWEA 4Z2NA 2KIEA 1WJ1A 2DN6A 2OQBA 2RVBB 4IOYX 2NZ8B 4HAYB 2UZSA 4WSFA 3MDBC 4P7IA 4Z2MB 2CY5A 3ODWA 4GZUA 1UNQA 1W1DA 1XODA 2R0DA 5D3YA 5C16A 4H8SA 2D9XA 2D11A 3FM8C 2MKRA 1P3RA 1DYNA 1KI1B 2CY4A 2MFQA 1Y19B 2L2IA 3P6AA 3D8EA 3DCXA 3NWFA 3FVCA 2DKQA 2CODA 2LKOA 2UVMA 4K2OA 1GC6A 2BCJA 3TFMA
chains in the Genus database with same CATH topology
2LYDA 4B6HA 4XWXA 1XX0A 3PVUA 2X18A 1MK9B 2GJYA 3PSCA 1MPHA 2COCA 2NMBA 2VRWB 2DKPA 4CHMA 2YT0A 4A6HA 1QQGA 2KGXB 5KQ1A 5J3TA 4YONA 1KZGA 2D9ZA 4NSWA 1V5PA 2D9WA 3SUZA 1UPRA 3V5WA 3CIKA 2YVCA 4A6KA 1MKEA 5D3XA 2MDXA 4CHJA 1P5TA 1E5WA 2GS0A 5DIFB 2W2WA 4NY0A 2ELAA 4KAXB 3VIAA 3U7DA 4WJ7A 1PMSA 1DDVA 5DI9B 3LJUX 1V5UA 3F0WA 3AU4A 2HE7A 2N0YA 3UZTA 3PG7A 2M38A 3SYXA 2MWNB 2K2UA 1I2HA 2QKLA 4MT7A 1U5FA 1WVHA 2JP2A 1K5GB 2COAA 4GXBA 2DX1A 1X05A 1FGZA 3ULCA 1EAZA 1EGXA 1FHWA 2D4QA 2HTHB 1OMWA 2Z0QA 4EJNA 1NU2A 2LOXA 1J19A 2RUKB 3KSYA 4KHOA 1V61A 5HE3A 1H4RA 3SV1A 3WYFB 2Y8GA 1FHOA 1TQZA 2M14A 3X23A 5GOWB 2D2QA 1X86A 3FEHA 3N7CA 2H7EA 1ISNA 1WGQA 2DHKA 3TVVA 2EC1A 4A6FA 5JP4A 4K17A 1PLSA 4MY6A 1V88A 2P0HA 5DHFB 4A5KA 2R09A 3KRXA 2EJ8A 4HAZB 1EF1A 4HB3B 2XQNM 4HATB 4TYZA 3PP2A 3PVWA 4DX90 5DH9B 1WG7A 2P8VA 2D9YA 5C79A 1QC6A 2KUPA 1V5MA 1ZC3B 4IFSA 2EMSA 3ULBA 2D10A 5DHAB 5HE0A 1GC7A 1I7AA 4DXAB 2V76A 4K81A 1XKEA 3HW2B 4A6FB 1TXDA 2IFSA 2RLOA 5J3YA 2LG1A 5EFXA 1U5EA 4HAXB 1Q67A 2Z0PA 4HAUB 4GN1A 1BAKA 3MPXA 3AU5A 2YS5A 1M7RA 4CYEA 3WA0A 2I1JA 5C5BA 1W1GA 4KHBB 5FI1A 3NSUA 3D8FA 3SNHA 5LOPB 2CAYA 1TJ6A 2K2JA 3HQCA 3QBVB 2KCJA 3QWMA 4YL8A 3KRWA 1NI2A 4F7UP 1GG3A 2Y7BA 2Y8FA 1WI1A 4HDOA 1MK7B 4IAPA 5FI0A 3TCAA 3ML4A 2ROVA 2W2XD 5C5BB 3RCPA 5L81A 1BTNA 1U2BA 1IRSA 1NTYA 1W1HA 4F7HA 2RGNB 5CLQB 4ZRKA 1V89A 4DX8A 3ODOA 1LB1A 4F7GA 4EMOA 2ZPYA 2I1KA 2YS1A 2VSZA 1RJ2A 4KVGB 1U27A 4DBBA 1P6SA 1DDWA 2J59M 1XCGA 1MIXA 2LULA 3GYOA 1J0WA 1RRPB 4PQ0A 1DDMA 4HB2B 4GMXB 2EMTA 1ZVRA 5KQ4A 1LW3A 3BJIA 3VOQA 2N23A 5LONB 3T06A 1U5DA 3FSSA 1SHCA 4KHAA 5CLLB 1FAOA 1AQCA 1OY2A 1NTVA 5D27A 2GCLA 3G9WA 3KZ1A 3M1IB 1X1GA 3DXDA 4BBKA 1UEFA 1FHXA 1M7EA 2I5CA 1N3HA 2RSGA 1UNRA 3OANA 1X11A 1FOEA 2P0FA 3AJ4A 1Y5OA 4PNKA 4HB4B 3KY9A 2D9VA 3HK0A 3DXEA 5C6RA 1B55A 2J0MA 3PEGA 2ADZA 2W2XC 4HAVB 5D3VA 3F5RA 2YF0A 3A8PA 2E2XA 3GYPA 2DX5A 1X1FA 1U5GA 2ELBA 2OTXA 2AEHA 1SGHA 3CXBB 3A98B 2J0KA 1DROA 5D3WA 3TW1A 5JLJB 2Z0OA 4K2PA 4C0AA 5JHHA 1FGYA 1UNPA 4HDQA 3O96A 1MIZB 1XR0B 2Q13A 3BINA 1UPQA 2PZ1A 1BWNA 4HHVA 3U8ZA 3PZDA 2G35A 4ZRIA 4GMVA 2QKMA 4MK0A 2DYNA 4D0NB 1BTKA 4TKNA 3TO1A 2LOZA 3SO6A 2AL6A 2VKIA 3P7ZA 4HB0B 1U29A 2YT1A 4WVFB 2CRFA 3IVFA 4L6EA 4EKUA 2RNRB 5J3QA 1PFJA 2GCJA 2FJLA 1H10A 1DBHA 1Z87A 4Y94A 2K00A 2DA0A 2DFKA 1K5DB 3ODXA 2I5FA 2J0JA 2COFA 5HE2A 1OQNA 4ZRJA 1ZC4B 2IYBA 2YSZA 2DHIA 1ZM0A 1MAIA 1FB8A 2DTCA 3PVLA 1WGUA 2UZRA 5JHGA 2DHJA 1KZ7A 1EVHA 2DYQA 5HE1A 1WJMA 2P0DA 5KCVA 4HAWB 3A8QA 2YS3A 3DXCA 3ZDTA 3ZVRA 2YRYA 1ZSQA 3D8DA 2H7DA 4GPTB 2L1CA 2ROZB 2DLWA 3QIJA 1XD4A 1AWEA 4Z2NA 1WJ1A 2DN6A 2OQBA 2RVBB 4IOYX 2NZ8B 4HAYB 2UZSA 4WSFA 3MDBC 4P7IA 4Z2MB 2CY5A 3ODWA 4GZUA 1UNQA 1W1DA 1XODA 2R0DA 5D3YA 5C16A 4H8SA 2D9XA 2D11A 3FM8C 2MKRA 1P3RA 1DYNA 1KI1B 2CY4A 2MFQA 1Y19B 2L2IA 3P6AA 3D8EA 2DKQA 2CODA 2LKOA 2UVMA 4K2OA 1GC6A 2BCJA 3TFMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2LYD A;  4B6H A;  4XWX A;  1XX0 A;  3PVU A;  2X18 A;  1MK9 B;  2GJY A;  3PSC A;  1MPH A;  2COC A;  2NMB A;  2VRW B;  2DKP A;  4CHM A;  2YT0 A;  4A6H A;  1QQG A;  2KGX B;  5KQ1 A;  5J3T A;  4YON A;  1KZG A;  2D9Z A;  4NSW A;  1V5P A;  2D9W A;  3SUZ A;  1UPR A;  3V5W A;  3CIK A;  2YVC A;  4A6K A;  1MKE A;  5D3X A;  2MDX A;  4CHJ A;  1P5T A;  1E5W A;  2GS0 A;  5DIF B;  2W2W A;  4NY0 A;  2ELA A;  4KAX B;  3VIA A;  3U7D A;  4WJ7 A;  1PMS A;  1DDV A;  5DI9 B;  3LJU X;  1V5U A;  3F0W A;  3AU4 A;  2HE7 A;  2N0Y A;  3UZT A;  3PG7 A;  2M38 A;  3SYX A;  2MWN B;  2K2U A;  1I2H A;  2QKL A;  4MT7 A;  1U5F A;  1WVH A;  2JP2 A;  1K5G B;  2COA A;  4GXB A;  2DX1 A;  1X05 A;  1FGZ A;  3ULC A;  1EAZ A;  1EGX A;  1FHW A;  2D4Q A;  2HTH B;  1OMW A;  2Z0Q A;  4EJN A;  1NU2 A;  2LOX A;  1J19 A;  2RUK B;  3KSY A;  4KHO A;  1V61 A;  5HE3 A;  1H4R A;  3SV1 A;  3WYF B;  2Y8G A;  1FHO A;  1TQZ A;  2M14 A;  3X23 A;  5GOW B;  2D2Q A;  1X86 A;  3FEH A;  3N7C A;  2H7E A;  1ISN A;  1WGQ A;  2DHK A;  3TVV A;  2EC1 A;  4A6F A;  5JP4 A;  4K17 A;  1PLS A;  4MY6 A;  1V88 A;  2P0H A;  5DHF B;  4A5K A;  2R09 A;  3KRX A;  2EJ8 A;  4HAZ B;  1EF1 A;  4HB3 B;  2XQN M;  4HAT B;  4TYZ A;  3PP2 A;  3PVW A;  4DX9 0;  5DH9 B;  1WG7 A;  2P8V A;  2D9Y A;  5C79 A;  1QC6 A;  2KUP A;  1V5M A;  1ZC3 B;  4IFS A;  2EMS A;  3ULB A;  2D10 A;  5DHA B;  5HE0 A;  1GC7 A;  1I7A A;  4DXA B;  2V76 A;  4K81 A;  1XKE A;  3HW2 B;  4A6F B;  1TXD A;  2IFS A;  2RLO A;  5J3Y A;  2LG1 A;  5EFX A;  1U5E A;  4HAX B;  1Q67 A;  2Z0P A;  4HAU B;  4GN1 A;  1BAK A;  3MPX A;  3AU5 A;  2YS5 A;  1M7R A;  4CYE A;  3WA0 A;  2I1J A;  5C5B A;  1W1G A;  4KHB B;  5FI1 A;  3NSU A;  3D8F A;  3SNH A;  5LOP B;  2CAY A;  1TJ6 A;  2K2J A;  3HQC A;  3QBV B;  2KCJ A;  3QWM A;  4YL8 A;  3KRW A;  1NI2 A;  4F7U P;  1GG3 A;  2Y7B A;  2Y8F A;  1WI1 A;  4HDO A;  1MK7 B;  4IAP A;  5FI0 A;  3TCA A;  3ML4 A;  2ROV A;  2W2X D;  5C5B B;  3RCP A;  5L81 A;  1BTN A;  1U2B A;  1IRS A;  1NTY A;  1W1H A;  4F7H A;  2RGN B;  5CLQ B;  4ZRK A;  1V89 A;  4DX8 A;  3ODO A;  1LB1 A;  4F7G A;  4EMO A;  2ZPY A;  2I1K A;  2YS1 A;  2VSZ A;  1RJ2 A;  4KVG B;  1U27 A;  4DBB A;  1P6S A;  1DDW A;  2J59 M;  1XCG A;  1MIX A;  2LUL A;  3GYO A;  1J0W A;  1RRP B;  4PQ0 A;  1DDM A;  4HB2 B;  4GMX B;  2EMT A;  1ZVR A;  5KQ4 A;  1LW3 A;  3BJI A;  3VOQ A;  2N23 A;  5LON B;  3T06 A;  1U5D A;  3FSS A;  1SHC A;  4KHA A;  5CLL B;  1FAO A;  1AQC A;  1OY2 A;  1NTV A;  5D27 A;  2GCL A;  3G9W A;  3KZ1 A;  3M1I B;  1X1G A;  3DXD A;  4BBK A;  1UEF A;  1FHX A;  1M7E A;  2I5C A;  1N3H A;  2RSG A;  1UNR A;  3OAN A;  1X11 A;  1FOE A;  2P0F A;  3AJ4 A;  1Y5O A;  4PNK A;  4HB4 B;  3KY9 A;  2D9V A;  3HK0 A;  3DXE A;  5C6R A;  1B55 A;  2J0M A;  3PEG A;  2ADZ A;  2W2X C;  4HAV B;  5D3V A;  3F5R A;  2YF0 A;  3A8P A;  2E2X A;  3GYP A;  2DX5 A;  1X1F A;  1U5G A;  2ELB A;  2OTX A;  2AEH A;  1SGH A;  3CXB B;  3A98 B;  2J0K A;  1DRO A;  5D3W A;  3TW1 A;  5JLJ B;  2Z0O A;  4K2P A;  4C0A A;  5JHH A;  1FGY A;  1UNP A;  4HDQ A;  3O96 A;  1MIZ B;  1XR0 B;  2Q13 A;  3BIN A;  1UPQ A;  2PZ1 A;  1BWN A;  4HHV A;  3U8Z A;  3PZD A;  2G35 A;  4ZRI A;  4GMV A;  2QKM A;  4MK0 A;  2DYN A;  4D0N B;  1BTK A;  4TKN A;  3TO1 A;  2LOZ A;  3SO6 A;  2AL6 A;  2VKI A;  3P7Z A;  4HB0 B;  1U29 A;  2YT1 A;  4WVF B;  2CRF A;  3IVF A;  4L6E A;  4EKU A;  2RNR B;  5J3Q A;  1PFJ A;  2GCJ A;  2FJL A;  1H10 A;  1DBH A;  1Z87 A;  4Y94 A;  2K00 A;  2DA0 A;  2DFK A;  1K5D B;  3ODX A;  2I5F A;  2J0J A;  2COF A;  5HE2 A;  1OQN A;  4ZRJ A;  1ZC4 B;  2IYB A;  2YSZ A;  2DHI A;  1ZM0 A;  1MAI A;  1FB8 A;  2DTC A;  3PVL A;  1WGU A;  2UZR A;  5JHG A;  2DHJ A;  1KZ7 A;  1EVH A;  2DYQ A;  5HE1 A;  1WJM A;  2P0D A;  5KCV A;  4HAW B;  3A8Q A;  2YS3 A;  3DXC A;  3ZDT A;  3ZVR A;  2YRY A;  1ZSQ A;  3D8D A;  2H7D A;  4GPT B;  2L1C A;  2ROZ B;  2DLW A;  3QIJ A;  1XD4 A;  1AWE A;  4Z2N A;  1WJ1 A;  2DN6 A;  2OQB A;  2RVB B;  4IOY X;  2NZ8 B;  4HAY B;  2UZS A;  4WSF A;  3MDB C;  4P7I A;  4Z2M B;  2CY5 A;  3ODW A;  4GZU A;  1UNQ A;  1W1D A;  1XOD A;  2R0D A;  5D3Y A;  5C16 A;  4H8S A;  2D9X A;  2D11 A;  3FM8 C;  2MKR A;  1P3R A;  1DYN A;  1KI1 B;  2CY4 A;  2MFQ A;  1Y19 B;  2L2I A;  3P6A A;  3D8E A;  2DKQ A;  2COD A;  2LKO A;  2UVM A;  4K2O A;  1GC6 A;  2BCJ A;  3TFM A; 
#chains in the Genus database with same CATH topology
 2LYD A;  4B6H A;  4QJ4 B;  4XWX A;  1XX0 A;  3PVU A;  2X18 A;  1MK9 B;  2GJY A;  2NBV A;  2ZKM X;  3PSC A;  1MPH A;  2COC A;  2NMB A;  3U12 A;  3HIE A;  2VRW B;  2DKP A;  4CHM A;  2YT0 A;  4A6H A;  1QQG A;  2KGX B;  5KQ1 A;  5J3T A;  4YON A;  1KZG A;  2D9Z A;  4NSW A;  1V5P A;  2D9W A;  2Z59 A;  3SUZ A;  1T77 A;  1UPR A;  3V5W A;  3CIK A;  2YVC A;  4A6K A;  1MKE A;  5D3X A;  2MDX A;  4CHJ A;  1P5T A;  1E5W A;  2GS0 A;  5DIF B;  2W2W A;  4NY0 A;  2ELA A;  4KAX B;  3VIA A;  3U7D A;  4WJ7 A;  4QXA B;  1PMS A;  2KUQ A;  1DDV A;  5DI9 B;  3LJU X;  1V5U A;  3F0W A;  3AU4 A;  4GNK B;  2HE7 A;  2N0Y A;  3UZT A;  3PG7 A;  2M38 A;  3SYX A;  4DIX A;  5IRS A;  2KR0 A;  2FJU B;  2K2U A;  2MWN B;  1I2H A;  2QKL A;  4MT7 A;  1U5F A;  1WVH A;  2JP2 A;  1K5G B;  1MI1 A;  2COA A;  4GXB A;  2DX1 A;  1X05 A;  1FGZ A;  3ULC A;  3HSA A;  1EAZ A;  1EGX A;  1FHW A;  2D4Q A;  2HTH B;  1OMW A;  2Z0Q A;  4EJN A;  1NU2 A;  2LOX A;  1J19 A;  2RUK B;  3KSY A;  4KHO A;  4CSQ A;  1V61 A;  5HE3 A;  1H4R A;  3SV1 A;  3WYF B;  2Y8G A;  1FHO A;  1TQZ A;  2M14 A;  2K8E A;  3X23 A;  5GOW B;  2D2Q A;  1X86 A;  3FEH A;  3N7C A;  2H7E A;  2Z4D A;  1ISN A;  1WGQ A;  2DHK A;  3TVV A;  2EC1 A;  4A6F A;  5JP4 A;  4K17 A;  1PLS A;  4MY6 A;  1V88 A;  2P0H A;  5DHF B;  4A5K A;  2R09 A;  3KRX A;  2EJ8 A;  4HAZ B;  1EF1 A;  4HB3 B;  2XQN M;  4HAT B;  4TYZ A;  3PP2 A;  3PVW A;  4DX9 0;  5DH9 B;  1WG7 A;  2P8V A;  2D9Y A;  5C79 A;  3NW8 A;  1QC6 A;  2KUP A;  1V5M A;  1ZC3 B;  4IFS A;  2EMS A;  3ULB A;  2D10 A;  5DHA B;  5HE0 A;  1GC7 A;  1I7A A;  4DXA B;  2V76 A;  4K81 A;  1XKE A;  3HW2 B;  4A6F B;  1TXD A;  2IFS A;  2RLO A;  4D6W A;  5J3Y A;  2LG1 A;  5EFX A;  2RRF A;  3B77 A;  1U5E A;  4HAX B;  1Q67 A;  2Z0P A;  4HAU B;  4GN1 A;  1BAK A;  3MPX A;  3AU5 A;  2YS5 A;  1M7R A;  4CYE A;  5LG4 B;  3WA0 A;  2I1J A;  5C5B A;  1W1G A;  4KHB B;  5FI1 A;  3NSU A;  3D8F A;  3SNH A;  5LOP B;  2CAY A;  1TJ6 A;  4L1R A;  2K2J A;  3HQC A;  3QBV B;  2KCJ A;  3QWM A;  4YL8 A;  3KRW A;  1NI2 A;  4F7U P;  1GG3 A;  2Y7B A;  2Y8F A;  3OHM B;  1WI1 A;  4HDO A;  1MK7 B;  4IAP A;  5FI0 A;  3TCA A;  3ML4 A;  2ROV A;  2W2X D;  2K49 A;  5C5B B;  3RCP A;  5I2S A;  5L81 A;  1BTN A;  1U2B A;  1IRS A;  3NWD A;  1NTY A;  1W1H A;  4F7H A;  2RGN B;  5CLQ B;  4ZRK A;  1V89 A;  4DX8 A;  3ODO A;  1LB1 A;  4F7G A;  4EMO A;  2ZPY A;  2I1K A;  2YS1 A;  2VSZ A;  1RJ2 A;  4KVG B;  1U27 A;  4DBB A;  1P6S A;  1DDW A;  2J59 M;  1XCG A;  1MIX A;  2LUL A;  3GYO A;  1J0W A;  1RRP B;  4PQ0 A;  1DDM A;  4HB2 B;  4GMX B;  2EMT A;  1ZVR A;  5KQ4 A;  1LW3 A;  3BJI A;  3VOQ A;  2N23 A;  5LON B;  3T06 A;  1U5D A;  3FSS A;  1SHC A;  4KHA A;  5CLL B;  1FAO A;  1AQC A;  1OY2 A;  1ZYI A;  1NTV A;  3A58 A;  5D27 A;  2GCL A;  3G9W A;  3KZ1 A;  3M1I B;  1X1G A;  3DXD A;  5M4Y B;  4BBK A;  1UEF A;  1FHX A;  1M7E A;  2I5C A;  1N3H A;  2RSG A;  1UNR A;  3OAN A;  1X11 A;  1FOE A;  2P0F A;  3AJ4 A;  1Y5O A;  4PNK A;  4HB4 B;  3KY9 A;  2D9V A;  3HK0 A;  4HSI A;  3DXE A;  5C6R A;  1B55 A;  2J0M A;  3PEG A;  2ADZ A;  2W2X C;  2KIG A;  4HAV B;  5D3V A;  4KHB A;  3F5R A;  2YF0 A;  3A8P A;  2E2X A;  3GYP A;  2DX5 A;  1X1F A;  1U5G A;  2ELB A;  2OTX A;  2AEH A;  1SGH A;  3CXB B;  4QJ3 B;  3A98 B;  2J0K A;  1DRO A;  4OT1 A;  5D3W A;  3TW1 A;  5JLJ B;  5I2M A;  2Z0O A;  4K2P A;  4C0A A;  5JHH A;  1FGY A;  1UNP A;  4HDQ A;  3O96 A;  1MIZ B;  1XR0 B;  2Q13 A;  3BIN A;  2Z14 A;  1UPQ A;  2PZ1 A;  1BWN A;  4HHV A;  3U8Z A;  3PZD A;  2G35 A;  4ZRI A;  4QJ5 B;  4GMV A;  2QKM A;  4MK0 A;  2DYN A;  4D0N B;  1BTK A;  4TKN A;  3TO1 A;  2LOZ A;  3SO6 A;  2AL6 A;  2YT2 A;  2VKI A;  3P7Z A;  4HB0 B;  1U29 A;  2YT1 A;  4WVF B;  2CRF A;  3IVF A;  4L6E A;  4EKU A;  2RNR B;  5J3Q A;  1PFJ A;  2GCJ A;  2FJL A;  1H10 A;  1DBH A;  1Z87 A;  4GOU A;  4Y94 A;  2K00 A;  2DA0 A;  2DFK A;  1K5D B;  2Z13 A;  3ODX A;  2I5F A;  2J0J A;  2COF A;  5HE2 A;  1OQN A;  4ZRJ A;  1ZC4 B;  2IYB A;  2YSZ A;  2DHI A;  1ZM0 A;  1MAI A;  1FB8 A;  2DTC A;  3PVL A;  1WGU A;  2UZR A;  5JHG A;  2DHJ A;  3NWA A;  1KZ7 A;  1EVH A;  2DYQ A;  5HE1 A;  1WJM A;  2P0D A;  5KCV A;  4HAW B;  3A8Q A;  4OSN A;  2YS3 A;  3DXC A;  3ZDT A;  2GUM A;  3ZVR A;  2YRY A;  1ZSQ A;  3D8D A;  2H7D A;  4GPT B;  2L1C A;  2ROZ B;  2DLW A;  3QIJ A;  2R2Y A;  1XD4 A;  1AWE A;  4Z2N A;  2KIE A;  1WJ1 A;  2DN6 A;  2OQB A;  2RVB B;  4IOY X;  2NZ8 B;  4HAY B;  2UZS A;  4WSF A;  3MDB C;  4P7I A;  4Z2M B;  2CY5 A;  3ODW A;  4GZU A;  1UNQ A;  1W1D A;  1XOD A;  2R0D A;  5D3Y A;  5C16 A;  4H8S A;  2D9X A;  2D11 A;  3FM8 C;  2MKR A;  1P3R A;  1DYN A;  1KI1 B;  2CY4 A;  2MFQ A;  1Y19 B;  2L2I A;  3P6A A;  3D8E A;  3DCX A;  3NWF A;  3FVC A;  2DKQ A;  2COD A;  2LKO A;  2UVM A;  4K2O A;  1GC6 A;  2BCJ A;  3TFM A; 
#chains in the Genus database with same CATH homology
 2LYD A;  4B6H A;  4XWX A;  1XX0 A;  3PVU A;  2X18 A;  1MK9 B;  2GJY A;  3PSC A;  1MPH A;  2COC A;  2NMB A;  2VRW B;  2DKP A;  4CHM A;  2YT0 A;  4A6H A;  1QQG A;  2KGX B;  5KQ1 A;  5J3T A;  4YON A;  1KZG A;  2D9Z A;  4NSW A;  1V5P A;  2D9W A;  3SUZ A;  1UPR A;  3V5W A;  3CIK A;  2YVC A;  4A6K A;  1MKE A;  5D3X A;  2MDX A;  4CHJ A;  1P5T A;  1E5W A;  2GS0 A;  5DIF B;  2W2W A;  4NY0 A;  2ELA A;  4KAX B;  3VIA A;  3U7D A;  4WJ7 A;  1PMS A;  1DDV A;  5DI9 B;  3LJU X;  1V5U A;  3F0W A;  3AU4 A;  2HE7 A;  2N0Y A;  3UZT A;  3PG7 A;  2M38 A;  3SYX A;  2MWN B;  2K2U A;  1I2H A;  2QKL A;  4MT7 A;  1U5F A;  1WVH A;  2JP2 A;  1K5G B;  2COA A;  4GXB A;  2DX1 A;  1X05 A;  1FGZ A;  3ULC A;  1EAZ A;  1EGX A;  1FHW A;  2D4Q A;  2HTH B;  1OMW A;  2Z0Q A;  4EJN A;  1NU2 A;  2LOX A;  1J19 A;  2RUK B;  3KSY A;  4KHO A;  1V61 A;  5HE3 A;  1H4R A;  3SV1 A;  3WYF B;  2Y8G A;  1FHO A;  1TQZ A;  2M14 A;  3X23 A;  5GOW B;  2D2Q A;  1X86 A;  3FEH A;  3N7C A;  2H7E A;  1ISN A;  1WGQ A;  2DHK A;  3TVV A;  2EC1 A;  4A6F A;  5JP4 A;  4K17 A;  1PLS A;  4MY6 A;  1V88 A;  2P0H A;  5DHF B;  4A5K A;  2R09 A;  3KRX A;  2EJ8 A;  4HAZ B;  1EF1 A;  4HB3 B;  2XQN M;  4HAT B;  4TYZ A;  3PP2 A;  3PVW A;  4DX9 0;  5DH9 B;  1WG7 A;  2P8V A;  2D9Y A;  5C79 A;  1QC6 A;  2KUP A;  1V5M A;  1ZC3 B;  4IFS A;  2EMS A;  3ULB A;  2D10 A;  5DHA B;  5HE0 A;  1GC7 A;  1I7A A;  4DXA B;  2V76 A;  4K81 A;  1XKE A;  3HW2 B;  4A6F B;  1TXD A;  2IFS A;  2RLO A;  5J3Y A;  2LG1 A;  5EFX A;  1U5E A;  4HAX B;  1Q67 A;  2Z0P A;  4HAU B;  4GN1 A;  1BAK A;  3MPX A;  3AU5 A;  2YS5 A;  1M7R A;  4CYE A;  3WA0 A;  2I1J A;  5C5B A;  1W1G A;  4KHB B;  5FI1 A;  3NSU A;  3D8F A;  3SNH A;  5LOP B;  2CAY A;  1TJ6 A;  2K2J A;  3HQC A;  3QBV B;  2KCJ A;  3QWM A;  4YL8 A;  3KRW A;  1NI2 A;  4F7U P;  1GG3 A;  2Y7B A;  2Y8F A;  1WI1 A;  4HDO A;  1MK7 B;  4IAP A;  5FI0 A;  3TCA A;  3ML4 A;  2ROV A;  2W2X D;  5C5B B;  3RCP A;  5L81 A;  1BTN A;  1U2B A;  1IRS A;  1NTY A;  1W1H A;  4F7H A;  2RGN B;  5CLQ B;  4ZRK A;  1V89 A;  4DX8 A;  3ODO A;  1LB1 A;  4F7G A;  4EMO A;  2ZPY A;  2I1K A;  2YS1 A;  2VSZ A;  1RJ2 A;  4KVG B;  1U27 A;  4DBB A;  1P6S A;  1DDW A;  2J59 M;  1XCG A;  1MIX A;  2LUL A;  3GYO A;  1J0W A;  1RRP B;  4PQ0 A;  1DDM A;  4HB2 B;  4GMX B;  2EMT A;  1ZVR A;  5KQ4 A;  1LW3 A;  3BJI A;  3VOQ A;  2N23 A;  5LON B;  3T06 A;  1U5D A;  3FSS A;  1SHC A;  4KHA A;  5CLL B;  1FAO A;  1AQC A;  1OY2 A;  1NTV A;  5D27 A;  2GCL A;  3G9W A;  3KZ1 A;  3M1I B;  1X1G A;  3DXD A;  4BBK A;  1UEF A;  1FHX A;  1M7E A;  2I5C A;  1N3H A;  2RSG A;  1UNR A;  3OAN A;  1X11 A;  1FOE A;  2P0F A;  3AJ4 A;  1Y5O A;  4PNK A;  4HB4 B;  3KY9 A;  2D9V A;  3HK0 A;  3DXE A;  5C6R A;  1B55 A;  2J0M A;  3PEG A;  2ADZ A;  2W2X C;  4HAV B;  5D3V A;  3F5R A;  2YF0 A;  3A8P A;  2E2X A;  3GYP A;  2DX5 A;  1X1F A;  1U5G A;  2ELB A;  2OTX A;  2AEH A;  1SGH A;  3CXB B;  3A98 B;  2J0K A;  1DRO A;  5D3W A;  3TW1 A;  5JLJ B;  2Z0O A;  4K2P A;  4C0A A;  5JHH A;  1FGY A;  1UNP A;  4HDQ A;  3O96 A;  1MIZ B;  1XR0 B;  2Q13 A;  3BIN A;  1UPQ A;  2PZ1 A;  1BWN A;  4HHV A;  3U8Z A;  3PZD A;  2G35 A;  4ZRI A;  4GMV A;  2QKM A;  4MK0 A;  2DYN A;  4D0N B;  1BTK A;  4TKN A;  3TO1 A;  2LOZ A;  3SO6 A;  2AL6 A;  2VKI A;  3P7Z A;  4HB0 B;  1U29 A;  2YT1 A;  4WVF B;  2CRF A;  3IVF A;  4L6E A;  4EKU A;  2RNR B;  5J3Q A;  1PFJ A;  2GCJ A;  2FJL A;  1H10 A;  1DBH A;  1Z87 A;  4Y94 A;  2K00 A;  2DA0 A;  2DFK A;  1K5D B;  3ODX A;  2I5F A;  2J0J A;  2COF A;  5HE2 A;  1OQN A;  4ZRJ A;  1ZC4 B;  2IYB A;  2YSZ A;  2DHI A;  1ZM0 A;  1MAI A;  1FB8 A;  2DTC A;  3PVL A;  1WGU A;  2UZR A;  5JHG A;  2DHJ A;  1KZ7 A;  1EVH A;  2DYQ A;  5HE1 A;  1WJM A;  2P0D A;  5KCV A;  4HAW B;  3A8Q A;  2YS3 A;  3DXC A;  3ZDT A;  3ZVR A;  2YRY A;  1ZSQ A;  3D8D A;  2H7D A;  4GPT B;  2L1C A;  2ROZ B;  2DLW A;  3QIJ A;  1XD4 A;  1AWE A;  4Z2N A;  1WJ1 A;  2DN6 A;  2OQB A;  2RVB B;  4IOY X;  2NZ8 B;  4HAY B;  2UZS A;  4WSF A;  3MDB C;  4P7I A;  4Z2M B;  2CY5 A;  3ODW A;  4GZU A;  1UNQ A;  1W1D A;  1XOD A;  2R0D A;  5D3Y A;  5C16 A;  4H8S A;  2D9X A;  2D11 A;  3FM8 C;  2MKR A;  1P3R A;  1DYN A;  1KI1 B;  2CY4 A;  2MFQ A;  1Y19 B;  2L2I A;  3P6A A;  3D8E A;  2DKQ A;  2COD A;  2LKO A;  2UVM A;  4K2O A;  1GC6 A;  2BCJ A;  3TFM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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