1LX5B

Crystal structure of the bmp7/actrii extracellular domain complex
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
94
structure length
94
Chain Sequence
ETQECLFFNANWERDRTNQTGVEPCYGDKDKRRHCFATWKNISGSIEIVKQGCWLDDINCYDRTDCIEKKDSPEVYFCCCEGNMCNEKFSYFPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The BMP7/ActRII Extracellular Domain Complex Provides New Insights into the Cooperative Nature of Receptor Assembly
pubmed doi rcsb
molecule keywords bone morphogenetic protein 7
molecule tags Growth factor/growth factor receptor
source organism Homo sapiens
total genus 20
structure length 94
sequence length 94
ec nomenclature ec 2.7.11.30: Receptor protein serine/threonine kinase.
pdb deposition date 2002-06-04
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.60.10 Mainly Beta Ribbon CD59 CD59 1lx5B00
4ZQYA 1COEA 5DO6A 1KL8A 2L5SA 1NORA 2HLQA 1CCQA 2K3GA 2MUPA 1ZADA 2H5FA 2J8BA 1LXGA 4EY8B 4IYEA 1NTXA 1QM7A 2LCRA 1NYSA 4BIKB 1CXOA 1KS6A 1CDRA 1H0JA 1MR6A 1LXHA 1QKEA 1REWC 3KFDI 3EVSC 1LX5B 3QB4B 1KC4A 3U73U 5IMTD 1LSIA 2LA1A 3KFDE 2X8BB 1VB0A 2QJ9C 1L4WA 1QKDA 4FAOC 2H7ZB 2UWRA 2H62D 1CRFA 3U74U 4XJJA 1FASA 2FD6U 1CREA 2QJBC 2QC1A 1IDGA 1IKCA 5EBXA 2H7ZA 2PJYB 1MAHF 1XT3A 2CRSA 2H64B 1I02A 1V6PA 3FEVA 2H62C 2NBTA 1RGJA 1JE9A 1CTXA 3ERAA 1CB9A 2MJYA 1IJCA 4LFTA 2MUOA 2CRTA 3PLCA 1FSCA 1BXPA 1JGKA 1CODA 1NEAA 2JQPA 1FFJA 4RUDA 1IDHA 1BTEA 1KBSA 1IK8A 4BDTB 1CDSA 1TXAA 1FF4A 2PJYC 1W6BA 1JBDA 2H64C 5DZ5A 2ERAA 2MFAA 1G6MA 2JVEA 4UY2C 1HC9B 1KXIA 6EBXA 1CVOA 1CDTA 1IDLA 1HAJA 1NXBA 1B41B 4P7UA 2HLRA 4QTIU 5IMYC 1LJZA 1KTZB 2GOOB 1TXBA 1FSSB 2UX2A 1HC9A 1CDQA 3EBXA 1KBTA 3NEQA 1TFSA 2VLWA 1HOYA 1ERAA 1KFHA 2H8UA 1ERGA 3BT2U 3LAQU 1YWHA 1F8UB 1PLOA 4OM4A 2BTXA 4OM5A 4DO8A 4HQPF 2ABXA 1HAAA 1M9ZA 4FAOE 2QJAC 1IDIA 1RL5A 2GOOC 3BT1U 2CCXA 1ONJA 1NTNA 1FRAA 1UG4A 3HH7A 1F94A 1S4YA 2OFSA 2MHYA 4AEAA 2BHIA 3NH7A 2CTXA 3VTSA 2CDXA 1KBAA 1DRSA 1KU6B 1NYUA 2MJ4A 2L03A 1CHVS 1ES7B 2N99A 1ABTA 1IQ9A 2MJ0A 1CXNA 3NDSA 5DU1A 1TGXA 2I9BE
chains in the Genus database with same CATH superfamily
4ZQYA 1COEA 5DO6A 1KL8A 2L5SA 1NORA 2HLQA 1CCQA 2K3GA 2MUPA 1ZADA 2H5FA 2J8BA 1LXGA 4EY8B 4IYEA 1NTXA 1QM7A 2LCRA 1NYSA 4BIKB 1CXOA 1KS6A 1CDRA 1H0JA 1MR6A 1LXHA 1QKEA 1REWC 3KFDI 3EVSC 1LX5B 3QB4B 1KC4A 3U73U 5IMTD 1LSIA 2LA1A 3KFDE 2X8BB 1VB0A 2QJ9C 1L4WA 1QKDA 4FAOC 2H7ZB 2UWRA 2H62D 1CRFA 3U74U 4XJJA 1FASA 2FD6U 1CREA 2QJBC 2QC1A 1IDGA 1IKCA 5EBXA 2H7ZA 2PJYB 1MAHF 1XT3A 2CRSA 2H64B 1I02A 1V6PA 3FEVA 2H62C 2NBTA 1RGJA 1JE9A 1CTXA 3ERAA 1CB9A 2MJYA 1IJCA 4LFTA 2MUOA 2CRTA 3PLCA 1FSCA 1BXPA 1JGKA 1CODA 1NEAA 2JQPA 1FFJA 4RUDA 1IDHA 1BTEA 1KBSA 1IK8A 4BDTB 1CDSA 1TXAA 1FF4A 2PJYC 4KSNA 1W6BA 1JBDA 2H64C 5DZ5A 2ERAA 2MFAA 1G6MA 2JVEA 4UY2C 1HC9B 1KXIA 6EBXA 1CVOA 1CDTA 1IDLA 1HAJA 1NXBA 1B41B 4P7UA 2HLRA 4QTIU 5IMYC 1LJZA 1KTZB 2GOOB 1TXBA 1FSSB 2UX2A 1HC9A 1CDQA 3EBXA 1KBTA 3NEQA 1TFSA 2VLWA 1HOYA 1ERAA 1KFHA 2H8UA 1ERGA 3BT2U 3LAQU 1YWHA 1F8UB 1PLOA 4OM4A 2BTXA 4OM5A 4DO8A 4HQPF 2ABXA 1HAAA 1M9ZA 4FAOE 2QJAC 1IDIA 1RL5A 2GOOC 3BT1U 2CCXA 1ONJA 1NTNA 1FRAA 1UG4A 3HH7A 1F94A 1S4YA 2OFSA 2MHYA 4AEAA 2BHIA 3NH7A 2CTXA 3VTSA 2CDXA 1KBAA 1DRSA 1KU6B 1NYUA 2MJ4A 2L03A 1CHVS 1ES7B 2N99A 1ABTA 1IQ9A 2MJ0A 1CXNA 3NDSA 5DU1A 1TGXA 2I9BE
chains in the Genus database with same CATH topology
4ZQYA 1COEA 5DO6A 1KL8A 2L5SA 1NORA 2HLQA 1CCQA 2K3GA 2MUPA 1ZADA 2H5FA 2J8BA 1LXGA 4EY8B 4IYEA 1NTXA 1QM7A 2LCRA 1NYSA 4BIKB 1CXOA 1KS6A 1CDRA 1H0JA 1MR6A 1LXHA 1QKEA 1REWC 3KFDI 3EVSC 1LX5B 3QB4B 1KC4A 3U73U 5IMTD 1LSIA 2LA1A 3KFDE 2X8BB 1VB0A 2QJ9C 1L4WA 1QKDA 4FAOC 2H7ZB 2UWRA 2H62D 1CRFA 3U74U 4XJJA 1FASA 2FD6U 1CREA 2QJBC 2QC1A 1IDGA 1IKCA 5EBXA 2H7ZA 2PJYB 1MAHF 1XT3A 2CRSA 2H64B 1I02A 1V6PA 3FEVA 2H62C 2NBTA 1RGJA 1JE9A 1CTXA 3ERAA 1CB9A 2MJYA 1IJCA 4LFTA 2MUOA 2CRTA 3PLCA 1FSCA 1BXPA 1JGKA 1CODA 1NEAA 2JQPA 1FFJA 4RUDA 1IDHA 1BTEA 1KBSA 1IK8A 4BDTB 1CDSA 1TXAA 1FF4A 2PJYC 4KSNA 1W6BA 1JBDA 2H64C 5DZ5A 2ERAA 2MFAA 1G6MA 2JVEA 4UY2C 1HC9B 1KXIA 6EBXA 1CVOA 1CDTA 1IDLA 1HAJA 1NXBA 1B41B 4P7UA 2HLRA 4QTIU 5IMYC 1LJZA 1KTZB 2GOOB 1TXBA 1FSSB 2UX2A 1HC9A 1CDQA 3EBXA 1KBTA 3NEQA 1TFSA 2VLWA 1HOYA 1ERAA 1KFHA 2H8UA 1ERGA 3BT2U 3LAQU 1YWHA 1F8UB 1PLOA 4OM4A 2BTXA 4OM5A 4DO8A 4HQPF 2ABXA 1HAAA 1M9ZA 4FAOE 2QJAC 1IDIA 1RL5A 2GOOC 3BT1U 2CCXA 1ONJA 1NTNA 1FRAA 1UG4A 3HH7A 1F94A 1S4YA 2OFSA 2MHYA 4AEAA 2BHIA 3NH7A 2CTXA 3VTSA 2CDXA 1KBAA 1DRSA 1KU6B 1NYUA 2MJ4A 2L03A 1CHVS 1ES7B 2N99A 1ABTA 1IQ9A 2MJ0A 1CXNA 3NDSA 5DU1A 1TGXA 2I9BE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ZQY A;  1COE A;  5DO6 A;  1KL8 A;  2L5S A;  1NOR A;  2HLQ A;  1CCQ A;  2K3G A;  2MUP A;  1ZAD A;  2H5F A;  2J8B A;  1LXG A;  4EY8 B;  4IYE A;  1NTX A;  1QM7 A;  2LCR A;  1NYS A;  4BIK B;  1CXO A;  1KS6 A;  1CDR A;  1H0J A;  1MR6 A;  1LXH A;  1QKE A;  1REW C;  3KFD I;  3EVS C;  1LX5 B;  3QB4 B;  1KC4 A;  3U73 U;  5IMT D;  1LSI A;  2LA1 A;  3KFD E;  2X8B B;  1VB0 A;  2QJ9 C;  1L4W A;  1QKD A;  4FAO C;  2H7Z B;  2UWR A;  2H62 D;  1CRF A;  3U74 U;  4XJJ A;  1FAS A;  2FD6 U;  1CRE A;  2QJB C;  2QC1 A;  1IDG A;  1IKC A;  5EBX A;  2H7Z A;  2PJY B;  1MAH F;  1XT3 A;  2CRS A;  2H64 B;  1I02 A;  1V6P A;  3FEV A;  2H62 C;  2NBT A;  1RGJ A;  1JE9 A;  1CTX A;  3ERA A;  1CB9 A;  2MJY A;  1IJC A;  4LFT A;  2MUO A;  2CRT A;  3PLC A;  1FSC A;  1BXP A;  1JGK A;  1COD A;  1NEA A;  2JQP A;  1FFJ A;  4RUD A;  1IDH A;  1BTE A;  1KBS A;  1IK8 A;  4BDT B;  1CDS A;  1TXA A;  1FF4 A;  2PJY C;  1W6B A;  1JBD A;  2H64 C;  5DZ5 A;  2ERA A;  2MFA A;  1G6M A;  2JVE A;  4UY2 C;  1HC9 B;  1KXI A;  6EBX A;  1CVO A;  1CDT A;  1IDL A;  1HAJ A;  1NXB A;  1B41 B;  4P7U A;  2HLR A;  4QTI U;  5IMY C;  1LJZ A;  1KTZ B;  2GOO B;  1TXB A;  1FSS B;  2UX2 A;  1HC9 A;  1CDQ A;  3EBX A;  1KBT A;  3NEQ A;  1TFS A;  2VLW A;  1HOY A;  1ERA A;  1KFH A;  2H8U A;  1ERG A;  3BT2 U;  3LAQ U;  1YWH A;  1F8U B;  1PLO A;  4OM4 A;  2BTX A;  4OM5 A;  4DO8 A;  4HQP F;  2ABX A;  1HAA A;  1M9Z A;  4FAO E;  2QJA C;  1IDI A;  1RL5 A;  2GOO C;  3BT1 U;  2CCX A;  1ONJ A;  1NTN A;  1FRA A;  1UG4 A;  3HH7 A;  1F94 A;  1S4Y A;  2OFS A;  2MHY A;  4AEA A;  2BHI A;  3NH7 A;  2CTX A;  3VTS A;  2CDX A;  1KBA A;  1DRS A;  1KU6 B;  1NYU A;  2MJ4 A;  2L03 A;  1CHV S;  1ES7 B;  2N99 A;  1ABT A;  1IQ9 A;  2MJ0 A;  1CXN A;  3NDS A;  5DU1 A;  1TGX A;  2I9B E; 
#chains in the Genus database with same CATH topology
 4ZQY A;  1COE A;  5DO6 A;  1KL8 A;  2L5S A;  1NOR A;  2HLQ A;  1CCQ A;  2K3G A;  2MUP A;  1ZAD A;  2H5F A;  2J8B A;  1LXG A;  4EY8 B;  4IYE A;  1NTX A;  1QM7 A;  2LCR A;  1NYS A;  4BIK B;  1CXO A;  1KS6 A;  1CDR A;  1H0J A;  1MR6 A;  1LXH A;  1QKE A;  1REW C;  3KFD I;  3EVS C;  1LX5 B;  3QB4 B;  1KC4 A;  3U73 U;  5IMT D;  1LSI A;  2LA1 A;  3KFD E;  2X8B B;  1VB0 A;  2QJ9 C;  1L4W A;  1QKD A;  4FAO C;  2H7Z B;  2UWR A;  2H62 D;  1CRF A;  3U74 U;  4XJJ A;  1FAS A;  2FD6 U;  1CRE A;  2QJB C;  2QC1 A;  1IDG A;  1IKC A;  5EBX A;  2H7Z A;  2PJY B;  1MAH F;  1XT3 A;  2CRS A;  2H64 B;  1I02 A;  1V6P A;  3FEV A;  2H62 C;  2NBT A;  1RGJ A;  1JE9 A;  1CTX A;  3ERA A;  1CB9 A;  2MJY A;  1IJC A;  4LFT A;  2MUO A;  2CRT A;  3PLC A;  1FSC A;  1BXP A;  1JGK A;  1COD A;  1NEA A;  2JQP A;  1FFJ A;  4RUD A;  1IDH A;  1BTE A;  1KBS A;  1IK8 A;  4BDT B;  1CDS A;  1TXA A;  1FF4 A;  2PJY C;  4KSN A;  1W6B A;  1JBD A;  2H64 C;  5DZ5 A;  2ERA A;  2MFA A;  1G6M A;  2JVE A;  4UY2 C;  1HC9 B;  1KXI A;  6EBX A;  1CVO A;  1CDT A;  1IDL A;  1HAJ A;  1NXB A;  1B41 B;  4P7U A;  2HLR A;  4QTI U;  5IMY C;  1LJZ A;  1KTZ B;  2GOO B;  1TXB A;  1FSS B;  2UX2 A;  1HC9 A;  1CDQ A;  3EBX A;  1KBT A;  3NEQ A;  1TFS A;  2VLW A;  1HOY A;  1ERA A;  1KFH A;  2H8U A;  1ERG A;  3BT2 U;  3LAQ U;  1YWH A;  1F8U B;  1PLO A;  4OM4 A;  2BTX A;  4OM5 A;  4DO8 A;  4HQP F;  2ABX A;  1HAA A;  1M9Z A;  4FAO E;  2QJA C;  1IDI A;  1RL5 A;  2GOO C;  3BT1 U;  2CCX A;  1ONJ A;  1NTN A;  1FRA A;  1UG4 A;  3HH7 A;  1F94 A;  1S4Y A;  2OFS A;  2MHY A;  4AEA A;  2BHI A;  3NH7 A;  2CTX A;  3VTS A;  2CDX A;  1KBA A;  1DRS A;  1KU6 B;  1NYU A;  2MJ4 A;  2L03 A;  1CHV S;  1ES7 B;  2N99 A;  1ABT A;  1IQ9 A;  2MJ0 A;  1CXN A;  3NDS A;  5DU1 A;  1TGX A;  2I9B E; 
#chains in the Genus database with same CATH homology
 4ZQY A;  1COE A;  5DO6 A;  1KL8 A;  2L5S A;  1NOR A;  2HLQ A;  1CCQ A;  2K3G A;  2MUP A;  1ZAD A;  2H5F A;  2J8B A;  1LXG A;  4EY8 B;  4IYE A;  1NTX A;  1QM7 A;  2LCR A;  1NYS A;  4BIK B;  1CXO A;  1KS6 A;  1CDR A;  1H0J A;  1MR6 A;  1LXH A;  1QKE A;  1REW C;  3KFD I;  3EVS C;  1LX5 B;  3QB4 B;  1KC4 A;  3U73 U;  5IMT D;  1LSI A;  2LA1 A;  3KFD E;  2X8B B;  1VB0 A;  2QJ9 C;  1L4W A;  1QKD A;  4FAO C;  2H7Z B;  2UWR A;  2H62 D;  1CRF A;  3U74 U;  4XJJ A;  1FAS A;  2FD6 U;  1CRE A;  2QJB C;  2QC1 A;  1IDG A;  1IKC A;  5EBX A;  2H7Z A;  2PJY B;  1MAH F;  1XT3 A;  2CRS A;  2H64 B;  1I02 A;  1V6P A;  3FEV A;  2H62 C;  2NBT A;  1RGJ A;  1JE9 A;  1CTX A;  3ERA A;  1CB9 A;  2MJY A;  1IJC A;  4LFT A;  2MUO A;  2CRT A;  3PLC A;  1FSC A;  1BXP A;  1JGK A;  1COD A;  1NEA A;  2JQP A;  1FFJ A;  4RUD A;  1IDH A;  1BTE A;  1KBS A;  1IK8 A;  4BDT B;  1CDS A;  1TXA A;  1FF4 A;  2PJY C;  4KSN A;  1W6B A;  1JBD A;  2H64 C;  5DZ5 A;  2ERA A;  2MFA A;  1G6M A;  2JVE A;  4UY2 C;  1HC9 B;  1KXI A;  6EBX A;  1CVO A;  1CDT A;  1IDL A;  1HAJ A;  1NXB A;  1B41 B;  4P7U A;  2HLR A;  4QTI U;  5IMY C;  1LJZ A;  1KTZ B;  2GOO B;  1TXB A;  1FSS B;  2UX2 A;  1HC9 A;  1CDQ A;  3EBX A;  1KBT A;  3NEQ A;  1TFS A;  2VLW A;  1HOY A;  1ERA A;  1KFH A;  2H8U A;  1ERG A;  3BT2 U;  3LAQ U;  1YWH A;  1F8U B;  1PLO A;  4OM4 A;  2BTX A;  4OM5 A;  4DO8 A;  4HQP F;  2ABX A;  1HAA A;  1M9Z A;  4FAO E;  2QJA C;  1IDI A;  1RL5 A;  2GOO C;  3BT1 U;  2CCX A;  1ONJ A;  1NTN A;  1FRA A;  1UG4 A;  3HH7 A;  1F94 A;  1S4Y A;  2OFS A;  2MHY A;  4AEA A;  2BHI A;  3NH7 A;  2CTX A;  3VTS A;  2CDX A;  1KBA A;  1DRS A;  1KU6 B;  1NYU A;  2MJ4 A;  2L03 A;  1CHV S;  1ES7 B;  2N99 A;  1ABT A;  1IQ9 A;  2MJ0 A;  1CXN A;  3NDS A;  5DU1 A;  1TGX A;  2I9B E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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