1LY7A

The solution structure of the the c-terminal domain of frataxin, the protein responsible for friedreich ataxia
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
121
structure length
121
Chain Sequence
MDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Unknown function
molecule keywords frataxin
publication title Towards a structural understanding of Friedreich's ataxia: the solution structure of frataxin
pubmed doi rcsb
source organism Homo sapiens
total genus 21
structure length 121
sequence length 121
ec nomenclature ec 1.16.3.1: Ferroxidase.
pdb deposition date 2002-06-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01491 Frataxin_Cyay Frataxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.920.10 Alpha Beta 2-Layer Sandwich Metal Transport, Frataxin; Chain A Frataxin/CyaY 1ly7A00
3T3KA 1SOYA 3T3XA 1EW4A 3T3JA 2EFFA 3S5EA 1LY7A 2FQLA 2GA5A 3T3TA 4EC2A 4LK8A 3OERA 2P1XA 3S4MA 1EKGA 3S5FA 4JPDA 3T3LA 4HS5A 3S5DA 3OEQA 4LP1A
chains in the Genus database with same CATH superfamily
3T3KA 3A5PA 1SOYA 2FUG7 3IAS7 3SSCA 3T3XA 3IAM7 1EW4A 3T3JA 2EFFA 3I9V7 3SSEA 3S5EA 1LY7A 2FQLA 4P78C 2GA5A 3T3TA 4C26A 4EC2A 4LK8A 3OERA 2P1XA 3S4MA 3GD9A 1WHZA 3GD0A 1EKGA 3S5FA 4JPDA 3T3LA 1V5RA 4HS5A 3S5DA 3OEQA 3IMOA 3SSDA 4LP1A 1D2MA 4HEA7
chains in the Genus database with same CATH topology
3T3KA 1SOYA 3T3XA 1EW4A 3T3JA 2EFFA 3S5EA 1LY7A 2FQLA 2GA5A 3T3TA 4EC2A 4LK8A 3OERA 2P1XA 3S4MA 1EKGA 3S5FA 4JPDA 3T3LA 4HS5A 3S5DA 3OEQA 4LP1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3T3K A;  1SOY A;  3T3X A;  1EW4 A;  3T3J A;  2EFF A;  3S5E A;  1LY7 A;  2FQL A;  2GA5 A;  3T3T A;  4EC2 A;  4LK8 A;  3OER A;  2P1X A;  3S4M A;  1EKG A;  3S5F A;  4JPD A;  3T3L A;  4HS5 A;  3S5D A;  3OEQ A;  4LP1 A; 
#chains in the Genus database with same CATH topology
 3T3K A;  3A5P A;  1SOY A;  2FUG 7;  3IAS 7;  3SSC A;  3T3X A;  3IAM 7;  1EW4 A;  3T3J A;  2EFF A;  3I9V 7;  3SSE A;  3S5E A;  1LY7 A;  2FQL A;  4P78 C;  2GA5 A;  3T3T A;  4C26 A;  4EC2 A;  4LK8 A;  3OER A;  2P1X A;  3S4M A;  3GD9 A;  1WHZ A;  3GD0 A;  1EKG A;  3S5F A;  4JPD A;  3T3L A;  1V5R A;  4HS5 A;  3S5D A;  3OEQ A;  3IMO A;  3SSD A;  4LP1 A;  1D2M A;  4HEA 7; 
#chains in the Genus database with same CATH homology
 3T3K A;  1SOY A;  3T3X A;  1EW4 A;  3T3J A;  2EFF A;  3S5E A;  1LY7 A;  2FQL A;  2GA5 A;  3T3T A;  4EC2 A;  4LK8 A;  3OER A;  2P1X A;  3S4M A;  1EKG A;  3S5F A;  4JPD A;  3T3L A;  4HS5 A;  3S5D A;  3OEQ A;  4LP1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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