1M3GA

Solution structure of the catalytic domain of mapk phosphatase pac-1: insights into substrate-induced enzymatic activation
Total Genus 29
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
145
structure length
145
Chain Sequence
QGGPVEILPYLFLGSCSHSSDLQGLQACGITAVLNVSASCPNHFEGLFRYKSIPVEDNQMVEISAWFQEAIGFIDWVKNSGGRVLVHSQAGISRSATICLAYLMQSRRVRLDEAFDFVKQRRGVISPNFSFMGQLLQFETQVLCH
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Solution Structure of the MAPK Phosphatase PAC-1 Catalytic Domain Insights into Substrate-Induced Enzymatic Activation of MKP
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords DUAL SPECIFICITY PROTEIN PHOSPHATASE 2
total genus 29
structure length 145
sequence length 145
ec nomenclature ec 3.1.3.16: Protein-serine/threonine phosphatase.
pdb deposition date 2002-06-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00782 DSPc Dual specificity phosphatase, catalytic domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 1m3gA00
3QCLA 2YDUA 4D3PA 2CMBA 4YAAA 4OHLA 2GP0A 4GE6A 1YGRA 3O4TA 1J4XA 2I42A 2IMGA 3OLRA 2RF6A 3OMHA 1LARA 1OHEA 3RO1A 1YGUA 4ZRTA 4WU3A 2G59A 3BRHA 1YTWA 1C84A 3U96A 4NX8A 4Y14A 2QDMA 1NNYA 3I80A 1LQFA 3MMJA 3O3LA 1Q6MA 1Q6TA 2QCJA 2CNFA 2B4UA 2P6XA 2OC3A 3I36A 2H4KA 1G4WR 2C7SA 3MOWA 2Q05A 5IBMA 1OHCA 4R0SA 2J16B 2F6YA 2I6JA 3EU0A 4J51A 4PVGA 1C83A 4H1OA 2FJNA 2HC2A 4BJOA 3M4UA 2HNQA 2BGEA 2PSZA 4QAPA 3LJ8A 1M3GA 2VEXA 2HCMA 3ZM0A 3F99A 4GWFA 1PTTA 2A3KA 1XXPA 3ZMPA 1Q6PA 5GTJA 2F46A 4KYRA 2Y2FA 1PTYA 5K24A 4ZN5A 1XXVA 2H4GA 1D5RA 4NWFA 3QCNA 4MBBA 2HXPA 5KADA 3S3KA 3D1HA 2NLKA 2F6WA 1NO6A 1NZ7A 4GRZA 3F81A 2B4PA 3SR9A 4D3RA 5KAAA 1JF7A 2I6IA 1I9SA 2ESBA 1BZHA 3QCFA 3S4OA 1OEOX 2B4SA 2F6VA 1OEVA 1NWEA 2ZMMA 3NMEA 5KA0A 1L8KA 1GFYA 2QCTA 4RKKA 3RGOA 3CM3A 1AAXA 5KA8A 2E0TA 3O4UA 1QXKA 1V3AA 2CNHA 3EZZA 1VHRA 3D1OA 4WOHA 4NYHA 1XBOA 1OEUA 4H34A 1PTUA 1ZCKA 1ONZA 1P15A 4JBCA 2I75A 4I8NA 5BUGA 1ECVA 1Q1MA 2BV5A 2CFVA 5KA2A 3QCHA 2CNGA 1Q6JA 2I1YA 4OHEA 2H04A 2M3VA 2I3UA 2PQ5A 2CM8A 3QCEA 1OHDA 2VEUA 3BM8A 4WTYA 4QBWA 2AZRA 2HY3A 1PA9A 1YTSA 2OZ5A 4RI4A 2B07A 3EMUA 3O4SA 3V0DA 1YWFA 2OUDA 4OHHA 4OHDA 3BLTA 2DXPA 1GWZA 5MMZB 4AZ1A 2CMAA 5KA9A 2VEYA 1LYVA 2PI7A 4BPCA 3S3HA 2GWOA 3V0EA 2HB1A 3QCCA 3D44A 2Y96A 4GE5A 3N0AA 4RHGA 2I3RA 3ZMQA 2NT7A 3S4EA 3RGQA 4KI9A 2F6FA 4YR8B 2SHPA 4KYQA 4Z6BA 5AWXA 2HC1A 4HRFA 2PT0A 2HVLA 2B4OA 5BZZA 2G6ZA 1OEMX 1PH0A 1PXHA 2QEPA 2GJTA 4GS0A 1BZJA 4GFUA 3CWEA 2J17A 4ERCA 2QDPA 1WRMA 2CM3A 5M43A 2CM2A 2NZ6A 3GXGA 3D9CA 2JJDA 3EAXA 1OESA 1U26A 2A8BA 2AHSA 1KAKA 4RH9A 1YTNA 4R0TA 1G1HA 3I7ZA 5I6VA 1FQ1A 3QKQA 1RPMA 3A5JA 1QZ0A 3QCKA 3F9BA 3AWGA 1FPRA 3ZM3A 2I4EA 1MKPA 5HDEA 1I57A 5KACA 2F6ZA 4NNDA 4QBEA 4Y2EA 2QBPA 3PS5A 1XM2A 4RI5A 2I5XA 2B3OA 2VEWA 3QCMA 1U24A 1WCHA 1G7FA 1I9TA 2FH7A 1XRIA 2NV5A 1T49A 3QKPA 1EEOA 3V0FA 2OOQA 3AWFA 4ZI4A 4GRYA 2CM7A 4TVVA 5KA1A 3V0JA 4HJQA 4IKCA 1T48A 1G7GA 1C87A 3SMEA 5K9WA 2I6OA 1ZC0A 1X24A 1PTVA 1L8GA 5KA4A 3F9AA 5KA3A 3V0GA 3B7OA 3O5XA 4QAHA 3V0HA 1A5YA 3D42A 4B04A 5LXQB 3BLUA 2CMCA 5EHPA 1ZCLA 2WGPA 1G1FA 3ZM2A 3S3EA 2P4DA 4QUNA 1C88A 3AWEA 1YZ4A 2B49A 2BGDA 5K25A 1C86A 1OETA 2F6TA 3GXHA 3S3FA 2QBRA 3QCBA 4WU2A 1JLNA 1YFOA 3EB1A 2I4HA 3D1QA 1ONYA 1KAVA 1G1GA 5K23A 4D3QA 2CNIA 5IBSA 4GE2A 2H02A 4DGPA 3QCGA 1RXDA 1R6HA 2FJMA 4JMKA 5K22A 3ZM1A 2QBQA 4JNBA 2PA5A 2Q47A 1WAXA 4R30A 2C46A 1YPTA 2F70A 2HNPA 4RDDA 3ZV2A 1SUGA 3H2XA 2CJZA 1EENA 5KA7A 4ICZA 1PYNA 1T4JA 2ZN7A 4OHIA 3MOZA 4RH5A 2H4VA 3V0IA 3QCIA 1ZZWA 2J16A 2NT2A 4JMJA 5K9VA 5BZXA 2QDCA 2H03A 2I4GA 4GFVA 2BZLA 3QCDA 5J8RA 5EHRA 3RZ2A 4QUMA 2I6MA 2F71A 4NWGA 2MBCA 4S0GA 1NWLA 1FPZA 1U25A 5BX1A 3QCJA 3A5KA 3F41A 1Q6SA 2NTAA 1PA1A 4DGXA 1BZCA 2I6PA 2CNEA 1YN9A 2QBSA 4HJPA 2R0BA 2PBNA 1Q6NA 1C85A 1NL9A 2VEVA 1G4US 2BIJA 4PYHA 5KABA
chains in the Genus database with same CATH superfamily
3QCLA 2YDUA 4D3PA 5A5EA 2CMBA 1P31A 4YAAA 4OHLA 2GP0A 4GE6A 1YGRA 3O4TA 1J4XA 2I42A 5A5FA 2IMGA 3OLRA 2RF6A 3ZM5A 3OMHA 1LARA 1OHEA 3RO1A 1YGUA 4ZRTA 4WU3A 2F00A 2G59A 3BRHA 1JBVA 1YTWA 1C84A 3U96A 4NX8A 2VTDA 4Y14A 2QDMA 1NNYA 3I80A 4UAGA 1LQFA 3MMJA 3O3LA 1Q6MA 1Q6TA 1FGSA 2QCJA 4HV4A 2CNFA 2B4UA 2P6XA 2OC3A 2AM2A 3I36A 2H4KA 1G4WR 2C7SA 3MOWA 2Q05A 5IBMA 1OHCA 4R0SA 2J16B 2F6YA 2I6JA 3EU0A 4J51A 4PVGA 1C83A 4H1OA 2FJNA 2HC2A 4BJOA 3M4UA 2HNQA 2BGEA 2PSZA 4QAPA 3LJ8A 1M3GA 4CVLA 2VEXA 2HCMA 3ZM0A 3F99A 4GWFA 1PTTA 2A3KA 1XXPA 3ZMPA 1Q6PA 5GTJA 2F46A 4KYRA 1GG4A 2Y2FA 1PTYA 5K24A 4C12A 4ZN5A 1XXVA 2H4GA 1D5RA 4NWFA 3QCNA 4MBBA 2HXPA 5KADA 3S3KA 3D1HA 2NLKA 2F6WA 1NO6A 1NZ7A 4GRZA 3F81A 2B4PA 3SR9A 4D3RA 5KAAA 1JF7A 2I6IA 1I9SA 2ESBA 1BZHA 3QCFA 3S4OA 4BUBA 2VORA 1OEOX 2B4SA 2F6VA 1OEVA 1JBWA 1NWEA 2ZMMA 3NMEA 5KA0A 1L8KA 1GFYA 2QCTA 4RKKA 3RGOA 3CM3A 1AAXA 5KA8A 2E0TA 3O4UA 1QXKA 1V3AA 2CNHA 3EZZA 2JFFA 1E8CA 1VHRA 3D1OA 4WOHA 4NYHA 1XBOA 1OEUA 4H34A 1PTUA 1ZCKA 1ONZA 1P15A 4JBCA 2I75A 4I8NA 5BUGA 1ECVA 1Q1MA 2BV5A 2CFVA 5KA2A 1UAGA 1W78A 3QCHA 2CNGA 1Q6JA 2I1YA 4OHEA 2H04A 3NRSA 2M3VA 4C13A 1EEHA 2I3UA 2PQ5A 2CM8A 3QCEA 1OHDA 2VEUA 3BM8A 4WTYA 4QBWA 2AZRA 2HY3A 1PA9A 1YTSA 2OZ5A 4RI4A 2B07A 3EMUA 3O4SA 3V0DA 1YWFA 2OUDA 4OHHA 4OHDA 3BLTA 2DXPA 1GWZA 5MMZB 4AZ1A 2CMAA 5KA9A 3PYZA 2X5OA 2VEYA 2XPCA 1W7KA 1LYVA 2PI7A 4BPCA 4QF5A 3S3HA 2GWOA 3V0EA 2HB1A 3QCCA 3D44A 2WJPA 2Y96A 4GE5A 3N0AA 4RHGA 2I3RA 3ZMQA 2NT7A 3S4EA 3RGQA 4KI9A 3ZL8A 2F6FA 2UAGA 2SHPA 4KYQA 4YR8B 4Z6BA 5AWXA 2HC1A 4HRFA 2PT0A 2HVLA 2B4OA 5BZZA 1P3DA 2G6ZA 1OEMX 1PH0A 2Y66A 1PXHA 2QEPA 2GJTA 1J6UA 4GS0A 1BZJA 4GFUA 3CWEA 2J17A 4ERCA 2QDPA 1WRMA 2CM3A 5M43A 2JFGA 2CM2A 2NZ6A 3GXGA 3D9CA 2JJDA 3EAXA 1OESA 1U26A 2A8BA 2VOSA 2AHSA 1KAKA 4RH9A 1YTNA 4R0TA 1G1HA 3I7ZA 5I6VA 1FQ1A 3QKQA 1RPMA 3A5JA 2UUPA 1QZ0A 3QCKA 3F9BA 3AWGA 1FPRA 4CVKA 3ZM3A 2I4EA 1MKPA 5HDEA 1I57A 5KACA 2F6ZA 4NNDA 4QBEA 4Y2EA 2QBPA 2WTZA 3PS5A 1XM2A 4RI5A 2I5XA 2B3OA 2VEWA 1O5ZA 3QCMA 1U24A 1WCHA 1G7FA 1I9TA 2FH7A 1XRIA 2NV5A 1T49A 3QKPA 1EEOA 4CVMA 3V0FA 3QCZA 2OOQA 3AWFA 4ZI4A 4GRYA 2CM7A 4TVVA 5KA1A 3V0JA 2GC6A 4HJQA 4IKCA 1T48A 1G7GA 1C87A 3SMEA 5K9WA 2I6OA 1ZC0A 1X24A 1PTVA 1L8GA 5KA4A 3F9AA 3ZM6A 5KA3A 3V0GA 3B7OA 3O5XA 4QAHA 3V0HA 1A5YA 3D42A 1GQQA 4B04A 5LXQB 3BLUA 2CMCA 5EHPA 1ZCLA 2WGPA 1G1FA 3ZM2A 2VTEA 3HN7A 3S3EA 2P4DA 4QUNA 2GCBA 1C88A 2AM1A 4BUCA 3AWEA 1YZ4A 2B49A 2GC5A 2BGDA 5K25A 1C86A 1OETA 2F6TA 3GXHA 2GCAA 3S3FA 2QBRA 3N2AA 3QCBA 2UUOA 4ZIYA 4WU2A 1JLNA 1YFOA 3EB1A 2I4HA 3D1QA 1ONYA 1KAVA 1G1GA 5K23A 4D3QA 2CNIA 5IBSA 4GE2A 2XJAA 2H02A 1GQYA 4DGPA 3MVNA 3QCGA 1RXDA 1R6HA 2FJMA 2JFHA 4JMKA 5K22A 3ZM1A 2QBQA 4JNBA 2PA5A 2Q47A 1WAXA 4R30A 2Y67A 2C46A 1YPTA 2F70A 2HNPA 4RDDA 3ZV2A 1SUGA 3H2XA 2CJZA 1EENA 5KA7A 4ICZA 1PYNA 1T4JA 2ZN7A 4OHIA 3MOZA 4RH5A 2H4VA 3V0IA 3QCIA 1ZZWA 2J16A 2NT2A 4JMJA 4QDIA 3UAGA 5K9VA 5BZXA 2QDCA 2H03A 2I4GA 4GFVA 2BZLA 3QCDA 5J8RA 5EHRA 3RZ2A 4QUMA 2I6MA 2F71A 4NWGA 2MBCA 4S0GA 1NWLA 2Y1OA 1FPZA 1U25A 5BX1A 3QCJA 3A5KA 3F41A 2Y68A 1Q6SA 2NTAA 1PA1A 4DGXA 3LK7A 1BZCA 2I6PA 2CNEA 1YN9A 2QBSA 4HJPA 2R0BA 2PBNA 1Q6NA 1C85A 1E0DA 1NL9A 2VEVA 1G4US 2BIJA 4PYHA 5KABA
chains in the Genus database with same CATH topology
3QCLA 2YDUA 4D3PA 2CMBA 4YAAA 4OHLA 2GP0A 4GE6A 1YGRA 3O4TA 1J4XA 2I42A 2IMGA 3OLRA 2RF6A 3OMHA 1LARA 1OHEA 3RO1A 1YGUA 4ZRTA 4WU3A 2G59A 3BRHA 1YTWA 1C84A 3U96A 4NX8A 4Y14A 2QDMA 1NNYA 3I80A 1LQFA 3MMJA 3O3LA 1Q6MA 1Q6TA 2QCJA 2CNFA 2B4UA 2P6XA 2OC3A 3I36A 2H4KA 1G4WR 2C7SA 3MOWA 2Q05A 5IBMA 1OHCA 4R0SA 2J16B 2F6YA 2I6JA 3EU0A 4J51A 4PVGA 1C83A 4H1OA 2FJNA 2HC2A 4BJOA 3M4UA 2HNQA 2BGEA 2PSZA 4QAPA 3LJ8A 1M3GA 2VEXA 2HCMA 3ZM0A 3F99A 4GWFA 1PTTA 2A3KA 1XXPA 3ZMPA 1Q6PA 5GTJA 2F46A 4KYRA 2Y2FA 1PTYA 5K24A 4ZN5A 1XXVA 2H4GA 1D5RA 4NWFA 3QCNA 4MBBA 2HXPA 5KADA 3S3KA 3D1HA 2NLKA 2F6WA 1NO6A 1NZ7A 4GRZA 3F81A 2B4PA 3SR9A 4D3RA 5KAAA 1JF7A 2I6IA 1I9SA 2ESBA 1BZHA 3QCFA 3S4OA 1OEOX 2B4SA 2F6VA 1OEVA 1NWEA 2ZMMA 3NMEA 5KA0A 1L8KA 1GFYA 2QCTA 4RKKA 3RGOA 3CM3A 1AAXA 5KA8A 2E0TA 3O4UA 1QXKA 1V3AA 2CNHA 3EZZA 1VHRA 3D1OA 4WOHA 4NYHA 1XBOA 1OEUA 4H34A 1PTUA 1ZCKA 1ONZA 1P15A 4JBCA 2I75A 4I8NA 5BUGA 1ECVA 1Q1MA 2BV5A 2CFVA 5KA2A 3QCHA 2CNGA 1Q6JA 2I1YA 4OHEA 2H04A 2M3VA 2I3UA 2PQ5A 2CM8A 3QCEA 1OHDA 2VEUA 3BM8A 4WTYA 4QBWA 2AZRA 2HY3A 1PA9A 1YTSA 2OZ5A 4RI4A 2B07A 3EMUA 3O4SA 3V0DA 1YWFA 2OUDA 4OHHA 4OHDA 3BLTA 2DXPA 1GWZA 5MMZB 4AZ1A 2CMAA 5KA9A 2VEYA 1LYVA 2PI7A 4BPCA 3S3HA 2GWOA 3V0EA 2HB1A 3QCCA 3D44A 2Y96A 4GE5A 3N0AA 4RHGA 2I3RA 3ZMQA 2NT7A 3S4EA 3RGQA 4KI9A 2F6FA 4YR8B 2SHPA 4KYQA 4Z6BA 5AWXA 2HC1A 4HRFA 2PT0A 2HVLA 2B4OA 5BZZA 2G6ZA 1OEMX 1PH0A 1PXHA 2QEPA 2GJTA 4GS0A 1BZJA 4GFUA 3CWEA 2J17A 4ERCA 2QDPA 1WRMA 2CM3A 5M43A 2CM2A 2NZ6A 3GXGA 3D9CA 2JJDA 3EAXA 1OESA 1U26A 2A8BA 2AHSA 1KAKA 4RH9A 1YTNA 4R0TA 1G1HA 3I7ZA 5I6VA 1FQ1A 3QKQA 1RPMA 3A5JA 1QZ0A 3QCKA 3F9BA 3AWGA 1FPRA 3ZM3A 2I4EA 1MKPA 5HDEA 1I57A 5KACA 2F6ZA 4NNDA 4QBEA 4Y2EA 2QBPA 3PS5A 1XM2A 4RI5A 2I5XA 2B3OA 2VEWA 3QCMA 1U24A 1WCHA 1G7FA 1I9TA 2FH7A 1XRIA 2NV5A 1T49A 3QKPA 1EEOA 3V0FA 2OOQA 3AWFA 4ZI4A 4GRYA 2CM7A 4TVVA 5KA1A 3V0JA 4HJQA 4IKCA 1T48A 1G7GA 1C87A 3SMEA 5K9WA 2I6OA 1ZC0A 1X24A 1PTVA 1L8GA 5KA4A 3F9AA 5KA3A 3V0GA 3B7OA 3O5XA 4QAHA 3V0HA 1A5YA 3D42A 4B04A 5LXQB 3BLUA 2CMCA 5EHPA 1ZCLA 2WGPA 1G1FA 3ZM2A 3S3EA 2P4DA 4QUNA 1C88A 3AWEA 1YZ4A 2B49A 2BGDA 5K25A 1C86A 1OETA 2F6TA 3GXHA 3S3FA 2QBRA 3QCBA 4WU2A 1JLNA 1YFOA 3EB1A 2I4HA 3D1QA 1ONYA 1KAVA 1G1GA 5K23A 4D3QA 2CNIA 5IBSA 4GE2A 2H02A 4DGPA 3QCGA 1RXDA 1R6HA 2FJMA 4JMKA 5K22A 3ZM1A 2QBQA 4JNBA 2PA5A 2Q47A 1WAXA 4R30A 2C46A 1YPTA 2F70A 2HNPA 4RDDA 3ZV2A 1SUGA 3H2XA 2CJZA 1EENA 5KA7A 4ICZA 1PYNA 1T4JA 2ZN7A 4OHIA 3MOZA 4RH5A 2H4VA 3V0IA 3QCIA 1ZZWA 2J16A 2NT2A 4JMJA 5K9VA 5BZXA 2QDCA 2H03A 2I4GA 4GFVA 2BZLA 3QCDA 5J8RA 5EHRA 3RZ2A 4QUMA 2I6MA 2F71A 4NWGA 2MBCA 4S0GA 1NWLA 1FPZA 1U25A 5BX1A 3QCJA 3A5KA 3F41A 1Q6SA 2NTAA 1PA1A 4DGXA 1BZCA 2I6PA 2CNEA 1YN9A 2QBSA 4HJPA 2R0BA 2PBNA 1Q6NA 1C85A 1NL9A 2VEVA 1G4US 2BIJA 4PYHA 5KABA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QCL A;  2YDU A;  4D3P A;  2CMB A;  4YAA A;  4OHL A;  2GP0 A;  4GE6 A;  1YGR A;  3O4T A;  1J4X A;  2I42 A;  2IMG A;  3OLR A;  2RF6 A;  3OMH A;  1LAR A;  1OHE A;  3RO1 A;  1YGU A;  4ZRT A;  4WU3 A;  2G59 A;  3BRH A;  1YTW A;  1C84 A;  3U96 A;  4NX8 A;  4Y14 A;  2QDM A;  1NNY A;  3I80 A;  1LQF A;  3MMJ A;  3O3L A;  1Q6M A;  1Q6T A;  2QCJ A;  2CNF A;  2B4U A;  2P6X A;  2OC3 A;  3I36 A;  2H4K A;  1G4W R;  2C7S A;  3MOW A;  2Q05 A;  5IBM A;  1OHC A;  4R0S A;  2J16 B;  2F6Y A;  2I6J A;  3EU0 A;  4J51 A;  4PVG A;  1C83 A;  4H1O A;  2FJN A;  2HC2 A;  4BJO A;  3M4U A;  2HNQ A;  2BGE A;  2PSZ A;  4QAP A;  3LJ8 A;  1M3G A;  2VEX A;  2HCM A;  3ZM0 A;  3F99 A;  4GWF A;  1PTT A;  2A3K A;  1XXP A;  3ZMP A;  1Q6P A;  5GTJ A;  2F46 A;  4KYR A;  2Y2F A;  1PTY A;  5K24 A;  4ZN5 A;  1XXV A;  2H4G A;  1D5R A;  4NWF A;  3QCN A;  4MBB A;  2HXP A;  5KAD A;  3S3K A;  3D1H A;  2NLK A;  2F6W A;  1NO6 A;  1NZ7 A;  4GRZ A;  3F81 A;  2B4P A;  3SR9 A;  4D3R A;  5KAA A;  1JF7 A;  2I6I A;  1I9S A;  2ESB A;  1BZH A;  3QCF A;  3S4O A;  1OEO X;  2B4S A;  2F6V A;  1OEV A;  1NWE A;  2ZMM A;  3NME A;  5KA0 A;  1L8K A;  1GFY A;  2QCT A;  4RKK A;  3RGO A;  3CM3 A;  1AAX A;  5KA8 A;  2E0T A;  3O4U A;  1QXK A;  1V3A A;  2CNH A;  3EZZ A;  1VHR A;  3D1O A;  4WOH A;  4NYH A;  1XBO A;  1OEU A;  4H34 A;  1PTU A;  1ZCK A;  1ONZ A;  1P15 A;  4JBC A;  2I75 A;  4I8N A;  5BUG A;  1ECV A;  1Q1M A;  2BV5 A;  2CFV A;  5KA2 A;  3QCH A;  2CNG A;  1Q6J A;  2I1Y A;  4OHE A;  2H04 A;  2M3V A;  2I3U A;  2PQ5 A;  2CM8 A;  3QCE A;  1OHD A;  2VEU A;  3BM8 A;  4WTY A;  4QBW A;  2AZR A;  2HY3 A;  1PA9 A;  1YTS A;  2OZ5 A;  4RI4 A;  2B07 A;  3EMU A;  3O4S A;  3V0D A;  1YWF A;  2OUD A;  4OHH A;  4OHD A;  3BLT A;  2DXP A;  1GWZ A;  5MMZ B;  4AZ1 A;  2CMA A;  5KA9 A;  2VEY A;  1LYV A;  2PI7 A;  4BPC A;  3S3H A;  2GWO A;  3V0E A;  2HB1 A;  3QCC A;  3D44 A;  2Y96 A;  4GE5 A;  3N0A A;  4RHG A;  2I3R A;  3ZMQ A;  2NT7 A;  3S4E A;  3RGQ A;  4KI9 A;  2F6F A;  4YR8 B;  2SHP A;  4KYQ A;  4Z6B A;  5AWX A;  2HC1 A;  4HRF A;  2PT0 A;  2HVL A;  2B4O A;  5BZZ A;  2G6Z A;  1OEM X;  1PH0 A;  1PXH A;  2QEP A;  2GJT A;  4GS0 A;  1BZJ A;  4GFU A;  3CWE A;  2J17 A;  4ERC A;  2QDP A;  1WRM A;  2CM3 A;  5M43 A;  2CM2 A;  2NZ6 A;  3GXG A;  3D9C A;  2JJD A;  3EAX A;  1OES A;  1U26 A;  2A8B A;  2AHS A;  1KAK A;  4RH9 A;  1YTN A;  4R0T A;  1G1H A;  3I7Z A;  5I6V A;  1FQ1 A;  3QKQ A;  1RPM A;  3A5J A;  1QZ0 A;  3QCK A;  3F9B A;  3AWG A;  1FPR A;  3ZM3 A;  2I4E A;  1MKP A;  5HDE A;  1I57 A;  5KAC A;  2F6Z A;  4NND A;  4QBE A;  4Y2E A;  2QBP A;  3PS5 A;  1XM2 A;  4RI5 A;  2I5X A;  2B3O A;  2VEW A;  3QCM A;  1U24 A;  1WCH A;  1G7F A;  1I9T A;  2FH7 A;  1XRI A;  2NV5 A;  1T49 A;  3QKP A;  1EEO A;  3V0F A;  2OOQ A;  3AWF A;  4ZI4 A;  4GRY A;  2CM7 A;  4TVV A;  5KA1 A;  3V0J A;  4HJQ A;  4IKC A;  1T48 A;  1G7G A;  1C87 A;  3SME A;  5K9W A;  2I6O A;  1ZC0 A;  1X24 A;  1PTV A;  1L8G A;  5KA4 A;  3F9A A;  5KA3 A;  3V0G A;  3B7O A;  3O5X A;  4QAH A;  3V0H A;  1A5Y A;  3D42 A;  4B04 A;  5LXQ B;  3BLU A;  2CMC A;  5EHP A;  1ZCL A;  2WGP A;  1G1F A;  3ZM2 A;  3S3E A;  2P4D A;  4QUN A;  1C88 A;  3AWE A;  1YZ4 A;  2B49 A;  2BGD A;  5K25 A;  1C86 A;  1OET A;  2F6T A;  3GXH A;  3S3F A;  2QBR A;  3QCB A;  4WU2 A;  1JLN A;  1YFO A;  3EB1 A;  2I4H A;  3D1Q A;  1ONY A;  1KAV A;  1G1G A;  5K23 A;  4D3Q A;  2CNI A;  5IBS A;  4GE2 A;  2H02 A;  4DGP A;  3QCG A;  1RXD A;  1R6H A;  2FJM A;  4JMK A;  5K22 A;  3ZM1 A;  2QBQ A;  4JNB A;  2PA5 A;  2Q47 A;  1WAX A;  4R30 A;  2C46 A;  1YPT A;  2F70 A;  2HNP A;  4RDD A;  3ZV2 A;  1SUG A;  3H2X A;  2CJZ A;  1EEN A;  5KA7 A;  4ICZ A;  1PYN A;  1T4J A;  2ZN7 A;  4OHI A;  3MOZ A;  4RH5 A;  2H4V A;  3V0I A;  3QCI A;  1ZZW A;  2J16 A;  2NT2 A;  4JMJ A;  5K9V A;  5BZX A;  2QDC A;  2H03 A;  2I4G A;  4GFV A;  2BZL A;  3QCD A;  5J8R A;  5EHR A;  3RZ2 A;  4QUM A;  2I6M A;  2F71 A;  4NWG A;  2MBC A;  4S0G A;  1NWL A;  1FPZ A;  1U25 A;  5BX1 A;  3QCJ A;  3A5K A;  3F41 A;  1Q6S A;  2NTA A;  1PA1 A;  4DGX A;  1BZC A;  2I6P A;  2CNE A;  1YN9 A;  2QBS A;  4HJP A;  2R0B A;  2PBN A;  1Q6N A;  1C85 A;  1NL9 A;  2VEV A;  1G4U S;  2BIJ A;  4PYH A;  5KAB A; 
#chains in the Genus database with same CATH topology
 3QCL A;  2YDU A;  4D3P A;  5A5E A;  2CMB A;  1P31 A;  4YAA A;  4OHL A;  2GP0 A;  4GE6 A;  1YGR A;  3O4T A;  1J4X A;  2I42 A;  5A5F A;  2IMG A;  3OLR A;  2RF6 A;  3ZM5 A;  3OMH A;  1LAR A;  1OHE A;  3RO1 A;  1YGU A;  4ZRT A;  4WU3 A;  2F00 A;  2G59 A;  3BRH A;  1JBV A;  1YTW A;  1C84 A;  3U96 A;  4NX8 A;  2VTD A;  4Y14 A;  2QDM A;  1NNY A;  3I80 A;  4UAG A;  1LQF A;  3MMJ A;  3O3L A;  1Q6M A;  1Q6T A;  1FGS A;  2QCJ A;  4HV4 A;  2CNF A;  2B4U A;  2P6X A;  2OC3 A;  2AM2 A;  3I36 A;  2H4K A;  1G4W R;  2C7S A;  3MOW A;  2Q05 A;  5IBM A;  1OHC A;  4R0S A;  2J16 B;  2F6Y A;  2I6J A;  3EU0 A;  4J51 A;  4PVG A;  1C83 A;  4H1O A;  2FJN A;  2HC2 A;  4BJO A;  3M4U A;  2HNQ A;  2BGE A;  2PSZ A;  4QAP A;  3LJ8 A;  1M3G A;  4CVL A;  2VEX A;  2HCM A;  3ZM0 A;  3F99 A;  4GWF A;  1PTT A;  2A3K A;  1XXP A;  3ZMP A;  1Q6P A;  5GTJ A;  2F46 A;  4KYR A;  1GG4 A;  2Y2F A;  1PTY A;  5K24 A;  4C12 A;  4ZN5 A;  1XXV A;  2H4G A;  1D5R A;  4NWF A;  3QCN A;  4MBB A;  2HXP A;  5KAD A;  3S3K A;  3D1H A;  2NLK A;  2F6W A;  1NO6 A;  1NZ7 A;  4GRZ A;  3F81 A;  2B4P A;  3SR9 A;  4D3R A;  5KAA A;  1JF7 A;  2I6I A;  1I9S A;  2ESB A;  1BZH A;  3QCF A;  3S4O A;  4BUB A;  2VOR A;  1OEO X;  2B4S A;  2F6V A;  1OEV A;  1JBW A;  1NWE A;  2ZMM A;  3NME A;  5KA0 A;  1L8K A;  1GFY A;  2QCT A;  4RKK A;  3RGO A;  3CM3 A;  1AAX A;  5KA8 A;  2E0T A;  3O4U A;  1QXK A;  1V3A A;  2CNH A;  3EZZ A;  2JFF A;  1E8C A;  1VHR A;  3D1O A;  4WOH A;  4NYH A;  1XBO A;  1OEU A;  4H34 A;  1PTU A;  1ZCK A;  1ONZ A;  1P15 A;  4JBC A;  2I75 A;  4I8N A;  5BUG A;  1ECV A;  1Q1M A;  2BV5 A;  2CFV A;  5KA2 A;  1UAG A;  1W78 A;  3QCH A;  2CNG A;  1Q6J A;  2I1Y A;  4OHE A;  2H04 A;  3NRS A;  2M3V A;  4C13 A;  1EEH A;  2I3U A;  2PQ5 A;  2CM8 A;  3QCE A;  1OHD A;  2VEU A;  3BM8 A;  4WTY A;  4QBW A;  2AZR A;  2HY3 A;  1PA9 A;  1YTS A;  2OZ5 A;  4RI4 A;  2B07 A;  3EMU A;  3O4S A;  3V0D A;  1YWF A;  2OUD A;  4OHH A;  4OHD A;  3BLT A;  2DXP A;  1GWZ A;  5MMZ B;  4AZ1 A;  2CMA A;  5KA9 A;  3PYZ A;  2X5O A;  2VEY A;  2XPC A;  1W7K A;  1LYV A;  2PI7 A;  4BPC A;  4QF5 A;  3S3H A;  2GWO A;  3V0E A;  2HB1 A;  3QCC A;  3D44 A;  2WJP A;  2Y96 A;  4GE5 A;  3N0A A;  4RHG A;  2I3R A;  3ZMQ A;  2NT7 A;  3S4E A;  3RGQ A;  4KI9 A;  3ZL8 A;  2F6F A;  2UAG A;  2SHP A;  4KYQ A;  4YR8 B;  4Z6B A;  5AWX A;  2HC1 A;  4HRF A;  2PT0 A;  2HVL A;  2B4O A;  5BZZ A;  1P3D A;  2G6Z A;  1OEM X;  1PH0 A;  2Y66 A;  1PXH A;  2QEP A;  2GJT A;  1J6U A;  4GS0 A;  1BZJ A;  4GFU A;  3CWE A;  2J17 A;  4ERC A;  2QDP A;  1WRM A;  2CM3 A;  5M43 A;  2JFG A;  2CM2 A;  2NZ6 A;  3GXG A;  3D9C A;  2JJD A;  3EAX A;  1OES A;  1U26 A;  2A8B A;  2VOS A;  2AHS A;  1KAK A;  4RH9 A;  1YTN A;  4R0T A;  1G1H A;  3I7Z A;  5I6V A;  1FQ1 A;  3QKQ A;  1RPM A;  3A5J A;  2UUP A;  1QZ0 A;  3QCK A;  3F9B A;  3AWG A;  1FPR A;  4CVK A;  3ZM3 A;  2I4E A;  1MKP A;  5HDE A;  1I57 A;  5KAC A;  2F6Z A;  4NND A;  4QBE A;  4Y2E A;  2QBP A;  2WTZ A;  3PS5 A;  1XM2 A;  4RI5 A;  2I5X A;  2B3O A;  2VEW A;  1O5Z A;  3QCM A;  1U24 A;  1WCH A;  1G7F A;  1I9T A;  2FH7 A;  1XRI A;  2NV5 A;  1T49 A;  3QKP A;  1EEO A;  4CVM A;  3V0F A;  3QCZ A;  2OOQ A;  3AWF A;  4ZI4 A;  4GRY A;  2CM7 A;  4TVV A;  5KA1 A;  3V0J A;  2GC6 A;  4HJQ A;  4IKC A;  1T48 A;  1G7G A;  1C87 A;  3SME A;  5K9W A;  2I6O A;  1ZC0 A;  1X24 A;  1PTV A;  1L8G A;  5KA4 A;  3F9A A;  3ZM6 A;  5KA3 A;  3V0G A;  3B7O A;  3O5X A;  4QAH A;  3V0H A;  1A5Y A;  3D42 A;  1GQQ A;  4B04 A;  5LXQ B;  3BLU A;  2CMC A;  5EHP A;  1ZCL A;  2WGP A;  1G1F A;  3ZM2 A;  2VTE A;  3HN7 A;  3S3E A;  2P4D A;  4QUN A;  2GCB A;  1C88 A;  2AM1 A;  4BUC A;  3AWE A;  1YZ4 A;  2B49 A;  2GC5 A;  2BGD A;  5K25 A;  1C86 A;  1OET A;  2F6T A;  3GXH A;  2GCA A;  3S3F A;  2QBR A;  3N2A A;  3QCB A;  2UUO A;  4ZIY A;  4WU2 A;  1JLN A;  1YFO A;  3EB1 A;  2I4H A;  3D1Q A;  1ONY A;  1KAV A;  1G1G A;  5K23 A;  4D3Q A;  2CNI A;  5IBS A;  4GE2 A;  2XJA A;  2H02 A;  1GQY A;  4DGP A;  3MVN A;  3QCG A;  1RXD A;  1R6H A;  2FJM A;  2JFH A;  4JMK A;  5K22 A;  3ZM1 A;  2QBQ A;  4JNB A;  2PA5 A;  2Q47 A;  1WAX A;  4R30 A;  2Y67 A;  2C46 A;  1YPT A;  2F70 A;  2HNP A;  4RDD A;  3ZV2 A;  1SUG A;  3H2X A;  2CJZ A;  1EEN A;  5KA7 A;  4ICZ A;  1PYN A;  1T4J A;  2ZN7 A;  4OHI A;  3MOZ A;  4RH5 A;  2H4V A;  3V0I A;  3QCI A;  1ZZW A;  2J16 A;  2NT2 A;  4JMJ A;  4QDI A;  3UAG A;  5K9V A;  5BZX A;  2QDC A;  2H03 A;  2I4G A;  4GFV A;  2BZL A;  3QCD A;  5J8R A;  5EHR A;  3RZ2 A;  4QUM A;  2I6M A;  2F71 A;  4NWG A;  2MBC A;  4S0G A;  1NWL A;  2Y1O A;  1FPZ A;  1U25 A;  5BX1 A;  3QCJ A;  3A5K A;  3F41 A;  2Y68 A;  1Q6S A;  2NTA A;  1PA1 A;  4DGX A;  3LK7 A;  1BZC A;  2I6P A;  2CNE A;  1YN9 A;  2QBS A;  4HJP A;  2R0B A;  2PBN A;  1Q6N A;  1C85 A;  1E0D A;  1NL9 A;  2VEV A;  1G4U S;  2BIJ A;  4PYH A;  5KAB A; 
#chains in the Genus database with same CATH homology
 3QCL A;  2YDU A;  4D3P A;  2CMB A;  4YAA A;  4OHL A;  2GP0 A;  4GE6 A;  1YGR A;  3O4T A;  1J4X A;  2I42 A;  2IMG A;  3OLR A;  2RF6 A;  3OMH A;  1LAR A;  1OHE A;  3RO1 A;  1YGU A;  4ZRT A;  4WU3 A;  2G59 A;  3BRH A;  1YTW A;  1C84 A;  3U96 A;  4NX8 A;  4Y14 A;  2QDM A;  1NNY A;  3I80 A;  1LQF A;  3MMJ A;  3O3L A;  1Q6M A;  1Q6T A;  2QCJ A;  2CNF A;  2B4U A;  2P6X A;  2OC3 A;  3I36 A;  2H4K A;  1G4W R;  2C7S A;  3MOW A;  2Q05 A;  5IBM A;  1OHC A;  4R0S A;  2J16 B;  2F6Y A;  2I6J A;  3EU0 A;  4J51 A;  4PVG A;  1C83 A;  4H1O A;  2FJN A;  2HC2 A;  4BJO A;  3M4U A;  2HNQ A;  2BGE A;  2PSZ A;  4QAP A;  3LJ8 A;  1M3G A;  2VEX A;  2HCM A;  3ZM0 A;  3F99 A;  4GWF A;  1PTT A;  2A3K A;  1XXP A;  3ZMP A;  1Q6P A;  5GTJ A;  2F46 A;  4KYR A;  2Y2F A;  1PTY A;  5K24 A;  4ZN5 A;  1XXV A;  2H4G A;  1D5R A;  4NWF A;  3QCN A;  4MBB A;  2HXP A;  5KAD A;  3S3K A;  3D1H A;  2NLK A;  2F6W A;  1NO6 A;  1NZ7 A;  4GRZ A;  3F81 A;  2B4P A;  3SR9 A;  4D3R A;  5KAA A;  1JF7 A;  2I6I A;  1I9S A;  2ESB A;  1BZH A;  3QCF A;  3S4O A;  1OEO X;  2B4S A;  2F6V A;  1OEV A;  1NWE A;  2ZMM A;  3NME A;  5KA0 A;  1L8K A;  1GFY A;  2QCT A;  4RKK A;  3RGO A;  3CM3 A;  1AAX A;  5KA8 A;  2E0T A;  3O4U A;  1QXK A;  1V3A A;  2CNH A;  3EZZ A;  1VHR A;  3D1O A;  4WOH A;  4NYH A;  1XBO A;  1OEU A;  4H34 A;  1PTU A;  1ZCK A;  1ONZ A;  1P15 A;  4JBC A;  2I75 A;  4I8N A;  5BUG A;  1ECV A;  1Q1M A;  2BV5 A;  2CFV A;  5KA2 A;  3QCH A;  2CNG A;  1Q6J A;  2I1Y A;  4OHE A;  2H04 A;  2M3V A;  2I3U A;  2PQ5 A;  2CM8 A;  3QCE A;  1OHD A;  2VEU A;  3BM8 A;  4WTY A;  4QBW A;  2AZR A;  2HY3 A;  1PA9 A;  1YTS A;  2OZ5 A;  4RI4 A;  2B07 A;  3EMU A;  3O4S A;  3V0D A;  1YWF A;  2OUD A;  4OHH A;  4OHD A;  3BLT A;  2DXP A;  1GWZ A;  5MMZ B;  4AZ1 A;  2CMA A;  5KA9 A;  2VEY A;  1LYV A;  2PI7 A;  4BPC A;  3S3H A;  2GWO A;  3V0E A;  2HB1 A;  3QCC A;  3D44 A;  2Y96 A;  4GE5 A;  3N0A A;  4RHG A;  2I3R A;  3ZMQ A;  2NT7 A;  3S4E A;  3RGQ A;  4KI9 A;  2F6F A;  4YR8 B;  2SHP A;  4KYQ A;  4Z6B A;  5AWX A;  2HC1 A;  4HRF A;  2PT0 A;  2HVL A;  2B4O A;  5BZZ A;  2G6Z A;  1OEM X;  1PH0 A;  1PXH A;  2QEP A;  2GJT A;  4GS0 A;  1BZJ A;  4GFU A;  3CWE A;  2J17 A;  4ERC A;  2QDP A;  1WRM A;  2CM3 A;  5M43 A;  2CM2 A;  2NZ6 A;  3GXG A;  3D9C A;  2JJD A;  3EAX A;  1OES A;  1U26 A;  2A8B A;  2AHS A;  1KAK A;  4RH9 A;  1YTN A;  4R0T A;  1G1H A;  3I7Z A;  5I6V A;  1FQ1 A;  3QKQ A;  1RPM A;  3A5J A;  1QZ0 A;  3QCK A;  3F9B A;  3AWG A;  1FPR A;  3ZM3 A;  2I4E A;  1MKP A;  5HDE A;  1I57 A;  5KAC A;  2F6Z A;  4NND A;  4QBE A;  4Y2E A;  2QBP A;  3PS5 A;  1XM2 A;  4RI5 A;  2I5X A;  2B3O A;  2VEW A;  3QCM A;  1U24 A;  1WCH A;  1G7F A;  1I9T A;  2FH7 A;  1XRI A;  2NV5 A;  1T49 A;  3QKP A;  1EEO A;  3V0F A;  2OOQ A;  3AWF A;  4ZI4 A;  4GRY A;  2CM7 A;  4TVV A;  5KA1 A;  3V0J A;  4HJQ A;  4IKC A;  1T48 A;  1G7G A;  1C87 A;  3SME A;  5K9W A;  2I6O A;  1ZC0 A;  1X24 A;  1PTV A;  1L8G A;  5KA4 A;  3F9A A;  5KA3 A;  3V0G A;  3B7O A;  3O5X A;  4QAH A;  3V0H A;  1A5Y A;  3D42 A;  4B04 A;  5LXQ B;  3BLU A;  2CMC A;  5EHP A;  1ZCL A;  2WGP A;  1G1F A;  3ZM2 A;  3S3E A;  2P4D A;  4QUN A;  1C88 A;  3AWE A;  1YZ4 A;  2B49 A;  2BGD A;  5K25 A;  1C86 A;  1OET A;  2F6T A;  3GXH A;  3S3F A;  2QBR A;  3QCB A;  4WU2 A;  1JLN A;  1YFO A;  3EB1 A;  2I4H A;  3D1Q A;  1ONY A;  1KAV A;  1G1G A;  5K23 A;  4D3Q A;  2CNI A;  5IBS A;  4GE2 A;  2H02 A;  4DGP A;  3QCG A;  1RXD A;  1R6H A;  2FJM A;  4JMK A;  5K22 A;  3ZM1 A;  2QBQ A;  4JNB A;  2PA5 A;  2Q47 A;  1WAX A;  4R30 A;  2C46 A;  1YPT A;  2F70 A;  2HNP A;  4RDD A;  3ZV2 A;  1SUG A;  3H2X A;  2CJZ A;  1EEN A;  5KA7 A;  4ICZ A;  1PYN A;  1T4J A;  2ZN7 A;  4OHI A;  3MOZ A;  4RH5 A;  2H4V A;  3V0I A;  3QCI A;  1ZZW A;  2J16 A;  2NT2 A;  4JMJ A;  5K9V A;  5BZX A;  2QDC A;  2H03 A;  2I4G A;  4GFV A;  2BZL A;  3QCD A;  5J8R A;  5EHR A;  3RZ2 A;  4QUM A;  2I6M A;  2F71 A;  4NWG A;  2MBC A;  4S0G A;  1NWL A;  1FPZ A;  1U25 A;  5BX1 A;  3QCJ A;  3A5K A;  3F41 A;  1Q6S A;  2NTA A;  1PA1 A;  4DGX A;  1BZC A;  2I6P A;  2CNE A;  1YN9 A;  2QBS A;  4HJP A;  2R0B A;  2PBN A;  1Q6N A;  1C85 A;  1NL9 A;  2VEV A;  1G4U S;  2BIJ A;  4PYH A;  5KAB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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