1M7RA

Crystal structure of myotubularin-related protein-2 (mtmr2) complexed with phosphate
Total Genus 177
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
177
sequence length
513
structure length
513
Chain Sequence
EEPPLLPGENIKDMAKDVTYICPFTGAVRGTLTVTNYRLYFKSMERDPPFVLDASLGVINRVEKIGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPLFAFEYKEVFPENGWKLYDPLLEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPNIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHSSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFTNPLYGSYSNHVLYPVASMRHLELWVGYYIRWNPR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of a phosphoinositide phosphatase, MTMR2: insights into myotubular myopathy and Charcot-Marie-Tooth syndrome
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase
molecule keywords Myotubularin-related Protein-2
total genus 177
structure length 513
sequence length 513
chains with identical sequence B
ec nomenclature ec 3.1.3.64: Phosphatidylinositol-3-phosphatase.
pdb deposition date 2002-07-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02893 GRAM GRAM domain
A PF06602 Myotub-related Myotubularin-like phosphatase domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 1m7rA01
2ZPYA 4KHAA 3SNHA 1J19A 3TW1A 3KSYA 2DTCA 3SUZA 3KRWA 3AU4A 2NZ8B 2ELBA 1DDWA 1RJ2A 3ML4A 4K2PA 5C5BA 4HB4B 1FOEA 2KCJA 2PZ1A 3QWMA 2MKRA 2DA0A 2I1KA 3PEGA 2VSZA 5D3WA 5J3TA 4HDOA 2D9YA 3DXEA 1M7EA 3ULBA 1LW3A 5HE1A 3U8ZA 5J3QA 4GPTB 1QQGA 1UEFA 1NTVA 4PQ0A 3O96A 1DDVA 5HE0A 4A5KA 2YSZA 2N23A 3RCPA 2Z0PA 3LJUX 1XCGA 4CHMA 2DHJA 5DHFB 1U27A 2J0MA 4ZRKA 4D0NB 4PNKA 1M7RA 4DX8A 1DDMA 1U2BA 2LG1A 5J3YA 3QBVB 2DN6A 5D3YA 1K5GB 3DXCA 2AL6A 1BAKA 3A8QA 2RNRB 1SHCA 2LULA 2Q13A 1NI2A 5D3XA 2Y8FA 1Y19B 4HAUB 2AEHA 2CAYA 2KGXB 4A6FB 2UZSA 3IVFA 3ODOA 1W1DA 4KHBB 4GN1A 1FHOA 3F0WA 5C5BB 2CY4A 2E2XA 1P3RA 2LKOA 4F7UP 1FB8A 2DLWA 1MIXA 2JP2A 1EF1A 1BWNA 5C79A 2D2QA 1AQCA 2XQNM 1AWEA 1ZSQA 1B55A 4HAVB 5JHGA 3HQCA 5C6RA 4GZUA 2GS0A 3BJIA 4Z2MB 2RUKB 4K17A 3ODWA 5DH9B 1X11A 1MIZB 1UPQA 4HAXB 4C0AA 4GXBA 2DHIA 1UNQA 2EMSA 2HE7A 1Y5OA 5FI1A 2COAA 5D27A 4CYEA 5KQ4A 3N7CA 1TXDA 4HB3B 3P6AA 2DX1A 2ADZA 5JHHA 3TVVA 1V5PA 1U5FA 3CIKA 1WVHA 4KVGB 2FJLA 4GMXB 2QKLA 1J0WA 1TQZA 4YONA 3AJ4A 1GC7A 2D11A 1PFJA 4HAYB 1DROA 2W2XD 1XX0A 5CLLB 1X05A 2H7EA 2COCA 1MK7B 5JLJB 3FEHA 2LOZA 5C16A 2EJ8A 1FHWA 3TO1A 4ZRJA 2ELAA 3CXBB 3FSSA 2YS5A 2CRFA 2VKIA 2N0YA 4HB0B 3ODXA 1U29A 1V88A 1QC6A 4KAXB 4HAZB 1FAOA 4A6KA 4B6HA 1XR0B 3SYXA 1XKEA 4K2OA 2D9VA 1XODA 3GYOA 5LOPB 5KCVA 3M1IB 2I1JA 1X1FA 1WG7A 2YRYA 2J0JA 1UNPA 4WJ7A 2Z0QA 5EFXA 2D9XA 1MKEA 1LB1A 4HATB 3HW2B 2I5CA 1U5EA 1IRSA 2RGNB 4NSWA 3A98B 1GG3A 2L2IA 2GCLA 4EJNA 1K5DB 2BCJA 3MDBC 2YT0A 4TYZA 3D8EA 1WI1A 3D8FA 1FHXA 3WYFB 2H7DA 3PSCA 3X23A 2L1CA 3VOQA 2YVCA 1PLSA 1H10A 4IAPA 2IFSA 1U5GA 4DX90 1EAZA 4YL8A 4TKNA 5FI0A 3ZVRA 2LOXA 2D9WA 3F5RA 2LYDA 2OTXA 2K2JA 5KQ1A 2DX5A 2MDXA 2G35A 4HDQA 2DKQA 2YF0A 3PZDA 3FM8C 4P7IA 4Z2NA 3TFMA 3PP2A 1V61A 1NTYA 1N3HA 2M14A 3A8PA 1Z87A 3PVWA 1KZ7A 2NMBA 2RSGA 4ZRIA 1ZC4B 2DKPA 4MY6A 4WVFB 2K2UA 1MK9B 1Q67A 2P0FA 3QIJA 4DBBA 1ZC3B 3G9WA 3BINA 3HK0A 1X1GA 2UZRA 4NY0A 4CHJA 3T06A 1SGHA 1OQNA 2Y8GA 2YT1A 5D3VA 1UNRA 3U7DA 2M38A 1RRPB 3P7ZA 1WJMA 2KUPA 3UZTA 3ZDTA 3KY9A 4EKUA 4MT7A 2W2WA 2MWNB 2DHKA 2K00A 5LONB 4WSFA 3D8DA 2D4QA 1W1HA 1I2HA 1E5WA 1P5TA 5CLQB 2D10A 3AU5A 4F7HA 1FGYA 4BBKA 1KI1B 2ROVA 3DXDA 1BTNA 3SO6A 2X18A 1MPHA 4HB2B 2RVBB 4XWXA 3V5WA 2GJYA 2GCJA 2W2XC 4EMOA 1KZGA 1WGQA 3OANA 4DXAB 1TJ6A 1ISNA 5DHAB 2YS1A 2CY5A 5L81A 5HE3A 1UPRA 5DIFB 2UVMA 4MK0A 1GC6A 2J59M 2EC1A 1EVHA 3KZ1A 4GMVA 1FGZA 1EGXA 1PMSA 4IOYX 2YS3A 2ROZB 2DYQA 4K81A 3SV1A 1XD4A 3KRXA 1ZM0A 2D9ZA 2R09A 2Y7BA 2COFA 1V89A 2P0HA 2DYNA 2DFKA 3ULCA 1DBHA 3PVLA 4IFSA 1WGUA 4L6EA 1OMWA 1ZVRA 3MPXA 4A6FA 4KHOA 2Z0OA 3PVUA 3GYPA 1H4RA 1I7AA 2VRWB 1W1GA 5JP4A 4A6HA 1P6SA 3TCAA 4Y94A 2RLOA 1OY2A 2CODA 2P8VA 2MFQA 5DI9B 1V5MA 2EMTA 2R0DA 3WA0A 3PG7A 3VIAA 3NSUA 1DYNA 2P0DA 1MAIA 4HAWB 2HTHB 2IYBA 2OQBA 5HE2A 1NU2A 2J0KA 5GOWB 1BTKA 2V76A 1U5DA 2QKMA 2I5FA 1V5UA 4F7GA 1X86A 4H8SA 1WJ1A 4HHVA
chains in the Genus database with same CATH superfamily
2ZPYA 4KHAA 3SNHA 1J19A 3TW1A 3KSYA 2DTCA 3SUZA 3KRWA 3AU4A 2NZ8B 2ELBA 1DDWA 1RJ2A 3ML4A 4K2PA 5C5BA 4HB4B 4CSQA 1FOEA 2KCJA 2PZ1A 2R2YA 3QWMA 2MKRA 2DA0A 2I1KA 3PEGA 2VSZA 5D3WA 5J3TA 4HDOA 2D9YA 3DXEA 4QXAB 1M7EA 3NWAA 1LW3A 5HE1A 3ULBA 3U8ZA 5J3QA 4GPTB 2Z59A 1QQGA 1UEFA 1NTVA 4PQ0A 3O96A 1DDVA 5HE0A 4A5KA 2YSZA 2N23A 3RCPA 4OSNA 2Z0PA 2GUMA 3LJUX 3HIEA 1XCGA 4HSIA 4CHMA 2DHJA 5DHFB 1U27A 2J0MA 3OHMB 4ZRKA 4D0NB 4PNKA 1M7RA 4DX8A 1DDMA 5I2MA 1U2BA 2NBVA 2LG1A 5J3YA 3QBVB 2DN6A 5D3YA 5LG4B 1K5GB 3DXCA 2AL6A 1BAKA 3A8QA 2RNRB 1SHCA 2LULA 2Q13A 1NI2A 5D3XA 2Y8FA 1Y19B 4HAUB 2AEHA 2CAYA 2KGXB 4A6FB 2UZSA 3IVFA 3ODOA 1W1DA 4KHBB 4GN1A 1FHOA 3F0WA 5C5BB 2CY4A 2Z14A 2E2XA 1P3RA 2LKOA 2ZKMX 4F7UP 1FB8A 2DLWA 1MIXA 2JP2A 1EF1A 1BWNA 5C79A 2D2QA 1AQCA 2XQNM 1AWEA 1ZSQA 1B55A 4HAVB 5JHGA 3HQCA 5C6RA 4GZUA 2GS0A 3BJIA 4D6WA 1T77A 4Z2MB 2RUKB 4GNKB 5IRSA 4K17A 3ODWA 5DH9B 1X11A 1MIZB 1UPQA 4QJ4B 4HAXB 4C0AA 4GXBA 2DHIA 5M4YB 1UNQA 2EMSA 2HE7A 1Y5OA 5FI1A 2COAA 5D27A 4CYEA 5KQ4A 3N7CA 1TXDA 4HB3B 3P6AA 2DX1A 2ADZA 5JHHA 3TVVA 1V5PA 1U5FA 3CIKA 1WVHA 4KVGB 2FJLA 4GMXB 2QKLA 1J0WA 1TQZA 4YONA 3AJ4A 1GC7A 2D11A 1PFJA 4HAYB 1DROA 2W2XD 1XX0A 3B77A 1X05A 5CLLB 2H7EA 2COCA 1MK7B 5JLJB 3FEHA 2LOZA 5C16A 2EJ8A 1FHWA 3TO1A 4ZRJA 2ELAA 3CXBB 3FSSA 2YS5A 2CRFA 2VKIA 2N0YA 1MI1A 4HB0B 3ODXA 2K8EA 1U29A 1V88A 1QC6A 4KAXB 3DCXA 3NW8A 4HAZB 1FAOA 4A6KA 3NWDA 4B6HA 1XR0B 3SYXA 1XKEA 4K2OA 2D9VA 1XODA 3GYOA 5LOPB 5KCVA 3M1IB 2I1JA 1X1FA 1WG7A 2YRYA 2J0JA 1UNPA 4WJ7A 2Z0QA 2KIGA 5EFXA 2D9XA 1MKEA 1LB1A 4HATB 3HW2B 2I5CA 4OT1A 1U5EA 1IRSA 2RRFA 2RGNB 4NSWA 3A98B 1GG3A 2L2IA 2GCLA 1ZYIA 4EJNA 1K5DB 2BCJA 3MDBC 3HSAA 2YT0A 4TYZA 3D8EA 2KUQA 1WI1A 3A58A 3D8FA 1FHXA 3WYFB 2H7DA 3PSCA 3X23A 2L1CA 2K49A 3VOQA 2YVCA 1PLSA 1H10A 4IAPA 2IFSA 1U5GA 4DX90 1EAZA 4YL8A 4TKNA 5FI0A 3ZVRA 2LOXA 2D9WA 3F5RA 2LYDA 2OTXA 2K2JA 5KQ1A 2DX5A 2MDXA 2G35A 4HDQA 2DKQA 2YF0A 3PZDA 3FM8C 4P7IA 4Z2NA 3TFMA 3PP2A 1V61A 1NTYA 1N3HA 2M14A 3A8PA 1Z87A 3PVWA 1KZ7A 2NMBA 2RSGA 4ZRIA 1ZC4B 2DKPA 3FVCA 4MY6A 4WVFB 2K2UA 1MK9B 1Q67A 2P0FA 3QIJA 4DBBA 1ZC3B 3G9WA 3BINA 3HK0A 1X1GA 2UZRA 4NY0A 4CHJA 2KR0A 3T06A 1SGHA 1OQNA 2Y8GA 2YT1A 5D3VA 1UNRA 3U7DA 2M38A 1RRPB 3P7ZA 1WJMA 2KUPA 3UZTA 3ZDTA 3KY9A 4EKUA 4MT7A 2W2WA 2MWNB 2DHKA 2K00A 5LONB 4WSFA 3D8DA 2D4QA 1W1HA 1I2HA 1E5WA 1P5TA 5CLQB 2D10A 3AU5A 4F7HA 1FGYA 4BBKA 1KI1B 2ROVA 3DXDA 1BTNA 3SO6A 2X18A 1MPHA 4HB2B 2RVBB 4XWXA 3V5WA 2GJYA 2GCJA 2W2XC 2Z13A 4EMOA 1KZGA 1WGQA 3OANA 2YT2A 4GOUA 4DXAB 1TJ6A 1ISNA 5DHAB 3NWFA 2YS1A 2FJUB 2CY5A 2Z4DA 5L81A 5HE3A 1UPRA 5DIFB 2UVMA 4MK0A 1GC6A 2J59M 2EC1A 1EVHA 3KZ1A 4GMVA 1FGZA 1EGXA 2KIEA 5I2SA 1PMSA 4IOYX 2YS3A 2ROZB 2DYQA 4K81A 3SV1A 1XD4A 3KRXA 1ZM0A 2D9ZA 2R09A 2Y7BA 2COFA 1V89A 4QJ3B 2P0HA 2DYNA 2DFKA 3ULCA 1DBHA 4QJ5B 4KHBA 3PVLA 4IFSA 1WGUA 4L6EA 1OMWA 1ZVRA 3MPXA 4A6FA 4KHOA 2Z0OA 3PVUA 3GYPA 1H4RA 1I7AA 4L1RA 2VRWB 1W1GA 5JP4A 4A6HA 1P6SA 3TCAA 4Y94A 2RLOA 1OY2A 2CODA 2P8VA 2MFQA 5DI9B 1V5MA 2EMTA 2R0DA 3WA0A 3U12A 3PG7A 3VIAA 3NSUA 1DYNA 2P0DA 1MAIA 4HAWB 2HTHB 2IYBA 2OQBA 5HE2A 1NU2A 2J0KA 4DIXA 5GOWB 1BTKA 2V76A 1U5DA 2QKMA 2I5FA 1V5UA 4F7GA 1X86A 4H8SA 1WJ1A 4HHVA
chains in the Genus database with same CATH topology
2ZPYA 4KHAA 3SNHA 1J19A 3TW1A 3KSYA 2DTCA 3SUZA 3KRWA 3AU4A 2NZ8B 2ELBA 1DDWA 1RJ2A 3ML4A 4K2PA 5C5BA 4HB4B 1FOEA 2KCJA 2PZ1A 3QWMA 2MKRA 2DA0A 2I1KA 3PEGA 2VSZA 5D3WA 5J3TA 4HDOA 2D9YA 3DXEA 1M7EA 3ULBA 1LW3A 5HE1A 3U8ZA 5J3QA 4GPTB 1QQGA 1UEFA 1NTVA 4PQ0A 3O96A 1DDVA 5HE0A 4A5KA 2YSZA 2N23A 3RCPA 2Z0PA 3LJUX 1XCGA 4CHMA 2DHJA 5DHFB 1U27A 2J0MA 4ZRKA 4D0NB 4PNKA 1M7RA 4DX8A 1DDMA 1U2BA 2LG1A 5J3YA 3QBVB 2DN6A 5D3YA 1K5GB 3DXCA 2AL6A 1BAKA 3A8QA 2RNRB 1SHCA 2LULA 2Q13A 1NI2A 5D3XA 2Y8FA 1Y19B 4HAUB 2AEHA 2CAYA 2KGXB 4A6FB 2UZSA 3IVFA 3ODOA 1W1DA 4KHBB 4GN1A 1FHOA 3F0WA 5C5BB 2CY4A 2E2XA 1P3RA 2LKOA 4F7UP 1FB8A 2DLWA 1MIXA 2JP2A 1EF1A 1BWNA 5C79A 2D2QA 1AQCA 2XQNM 1AWEA 1ZSQA 1B55A 4HAVB 5JHGA 3HQCA 5C6RA 4GZUA 2GS0A 3BJIA 4Z2MB 2RUKB 4K17A 3ODWA 5DH9B 1X11A 1MIZB 1UPQA 4HAXB 4C0AA 4GXBA 2DHIA 1UNQA 2EMSA 2HE7A 1Y5OA 5FI1A 2COAA 5D27A 4CYEA 5KQ4A 3N7CA 1TXDA 4HB3B 3P6AA 2DX1A 2ADZA 5JHHA 3TVVA 1V5PA 1U5FA 3CIKA 1WVHA 4KVGB 2FJLA 4GMXB 2QKLA 1J0WA 1TQZA 4YONA 3AJ4A 1GC7A 2D11A 1PFJA 4HAYB 1DROA 2W2XD 1XX0A 5CLLB 1X05A 2H7EA 2COCA 1MK7B 5JLJB 3FEHA 2LOZA 5C16A 2EJ8A 1FHWA 3TO1A 4ZRJA 2ELAA 3CXBB 3FSSA 2YS5A 2CRFA 2VKIA 2N0YA 4HB0B 3ODXA 1U29A 1V88A 1QC6A 4KAXB 4HAZB 1FAOA 4A6KA 4B6HA 1XR0B 3SYXA 1XKEA 4K2OA 2D9VA 1XODA 3GYOA 5LOPB 5KCVA 3M1IB 2I1JA 1X1FA 1WG7A 2YRYA 2J0JA 1UNPA 4WJ7A 2Z0QA 5EFXA 2D9XA 1MKEA 1LB1A 4HATB 3HW2B 2I5CA 1U5EA 1IRSA 2RGNB 4NSWA 3A98B 1GG3A 2L2IA 2GCLA 4EJNA 1K5DB 2BCJA 3MDBC 2YT0A 4TYZA 3D8EA 1WI1A 3D8FA 1FHXA 3WYFB 2H7DA 3PSCA 3X23A 2L1CA 3VOQA 2YVCA 1PLSA 1H10A 4IAPA 2IFSA 1U5GA 4DX90 1EAZA 4YL8A 4TKNA 5FI0A 3ZVRA 2LOXA 2D9WA 3F5RA 2LYDA 2OTXA 2K2JA 5KQ1A 2DX5A 2MDXA 2G35A 4HDQA 2DKQA 2YF0A 3PZDA 3FM8C 4P7IA 4Z2NA 3TFMA 3PP2A 1V61A 1NTYA 1N3HA 2M14A 3A8PA 1Z87A 3PVWA 1KZ7A 2NMBA 2RSGA 4ZRIA 1ZC4B 2DKPA 4MY6A 4WVFB 2K2UA 1MK9B 1Q67A 2P0FA 3QIJA 4DBBA 1ZC3B 3G9WA 3BINA 3HK0A 1X1GA 2UZRA 4NY0A 4CHJA 3T06A 1SGHA 1OQNA 2Y8GA 2YT1A 5D3VA 1UNRA 3U7DA 2M38A 1RRPB 3P7ZA 1WJMA 2KUPA 3UZTA 3ZDTA 3KY9A 4EKUA 4MT7A 2W2WA 2MWNB 2DHKA 2K00A 5LONB 4WSFA 3D8DA 2D4QA 1W1HA 1I2HA 1E5WA 1P5TA 5CLQB 2D10A 3AU5A 4F7HA 1FGYA 4BBKA 1KI1B 2ROVA 3DXDA 1BTNA 3SO6A 2X18A 1MPHA 4HB2B 2RVBB 4XWXA 3V5WA 2GJYA 2GCJA 2W2XC 4EMOA 1KZGA 1WGQA 3OANA 4DXAB 1TJ6A 1ISNA 5DHAB 2YS1A 2CY5A 5L81A 5HE3A 1UPRA 5DIFB 2UVMA 4MK0A 1GC6A 2J59M 2EC1A 1EVHA 3KZ1A 4GMVA 1FGZA 1EGXA 1PMSA 4IOYX 2YS3A 2ROZB 2DYQA 4K81A 3SV1A 1XD4A 3KRXA 1ZM0A 2D9ZA 2R09A 2Y7BA 2COFA 1V89A 2P0HA 2DYNA 2DFKA 3ULCA 1DBHA 3PVLA 4IFSA 1WGUA 4L6EA 1OMWA 1ZVRA 3MPXA 4A6FA 4KHOA 2Z0OA 3PVUA 3GYPA 1H4RA 1I7AA 2VRWB 1W1GA 5JP4A 4A6HA 1P6SA 3TCAA 4Y94A 2RLOA 1OY2A 2CODA 2P8VA 2MFQA 5DI9B 1V5MA 2EMTA 2R0DA 3WA0A 3PG7A 3VIAA 3NSUA 1DYNA 2P0DA 1MAIA 4HAWB 2HTHB 2IYBA 2OQBA 5HE2A 1NU2A 2J0KA 5GOWB 1BTKA 2V76A 1U5DA 2QKMA 2I5FA 1V5UA 4F7GA 1X86A 4H8SA 1WJ1A 4HHVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZPY A;  4KHA A;  3SNH A;  1J19 A;  3TW1 A;  3KSY A;  2DTC A;  3SUZ A;  3KRW A;  3AU4 A;  2NZ8 B;  2ELB A;  1DDW A;  1RJ2 A;  3ML4 A;  4K2P A;  5C5B A;  4HB4 B;  1FOE A;  2KCJ A;  2PZ1 A;  3QWM A;  2MKR A;  2DA0 A;  2I1K A;  3PEG A;  2VSZ A;  5D3W A;  5J3T A;  4HDO A;  2D9Y A;  3DXE A;  1M7E A;  3ULB A;  1LW3 A;  5HE1 A;  3U8Z A;  5J3Q A;  4GPT B;  1QQG A;  1UEF A;  1NTV A;  4PQ0 A;  3O96 A;  1DDV A;  5HE0 A;  4A5K A;  2YSZ A;  2N23 A;  3RCP A;  2Z0P A;  3LJU X;  1XCG A;  4CHM A;  2DHJ A;  5DHF B;  1U27 A;  2J0M A;  4ZRK A;  4D0N B;  4PNK A;  1M7R A;  4DX8 A;  1DDM A;  1U2B A;  2LG1 A;  5J3Y A;  3QBV B;  2DN6 A;  5D3Y A;  1K5G B;  3DXC A;  2AL6 A;  1BAK A;  3A8Q A;  2RNR B;  1SHC A;  2LUL A;  2Q13 A;  1NI2 A;  5D3X A;  2Y8F A;  1Y19 B;  4HAU B;  2AEH A;  2CAY A;  2KGX B;  4A6F B;  2UZS A;  3IVF A;  3ODO A;  1W1D A;  4KHB B;  4GN1 A;  1FHO A;  3F0W A;  5C5B B;  2CY4 A;  2E2X A;  1P3R A;  2LKO A;  4F7U P;  1FB8 A;  2DLW A;  1MIX A;  2JP2 A;  1EF1 A;  1BWN A;  5C79 A;  2D2Q A;  1AQC A;  2XQN M;  1AWE A;  1ZSQ A;  1B55 A;  4HAV B;  5JHG A;  3HQC A;  5C6R A;  4GZU A;  2GS0 A;  3BJI A;  4Z2M B;  2RUK B;  4K17 A;  3ODW A;  5DH9 B;  1X11 A;  1MIZ B;  1UPQ A;  4HAX B;  4C0A A;  4GXB A;  2DHI A;  1UNQ A;  2EMS A;  2HE7 A;  1Y5O A;  5FI1 A;  2COA A;  5D27 A;  4CYE A;  5KQ4 A;  3N7C A;  1TXD A;  4HB3 B;  3P6A A;  2DX1 A;  2ADZ A;  5JHH A;  3TVV A;  1V5P A;  1U5F A;  3CIK A;  1WVH A;  4KVG B;  2FJL A;  4GMX B;  2QKL A;  1J0W A;  1TQZ A;  4YON A;  3AJ4 A;  1GC7 A;  2D11 A;  1PFJ A;  4HAY B;  1DRO A;  2W2X D;  1XX0 A;  5CLL B;  1X05 A;  2H7E A;  2COC A;  1MK7 B;  5JLJ B;  3FEH A;  2LOZ A;  5C16 A;  2EJ8 A;  1FHW A;  3TO1 A;  4ZRJ A;  2ELA A;  3CXB B;  3FSS A;  2YS5 A;  2CRF A;  2VKI A;  2N0Y A;  4HB0 B;  3ODX A;  1U29 A;  1V88 A;  1QC6 A;  4KAX B;  4HAZ B;  1FAO A;  4A6K A;  4B6H A;  1XR0 B;  3SYX A;  1XKE A;  4K2O A;  2D9V A;  1XOD A;  3GYO A;  5LOP B;  5KCV A;  3M1I B;  2I1J A;  1X1F A;  1WG7 A;  2YRY A;  2J0J A;  1UNP A;  4WJ7 A;  2Z0Q A;  5EFX A;  2D9X A;  1MKE A;  1LB1 A;  4HAT B;  3HW2 B;  2I5C A;  1U5E A;  1IRS A;  2RGN B;  4NSW A;  3A98 B;  1GG3 A;  2L2I A;  2GCL A;  4EJN A;  1K5D B;  2BCJ A;  3MDB C;  2YT0 A;  4TYZ A;  3D8E A;  1WI1 A;  3D8F A;  1FHX A;  3WYF B;  2H7D A;  3PSC A;  3X23 A;  2L1C A;  3VOQ A;  2YVC A;  1PLS A;  1H10 A;  4IAP A;  2IFS A;  1U5G A;  4DX9 0;  1EAZ A;  4YL8 A;  4TKN A;  5FI0 A;  3ZVR A;  2LOX A;  2D9W A;  3F5R A;  2LYD A;  2OTX A;  2K2J A;  5KQ1 A;  2DX5 A;  2MDX A;  2G35 A;  4HDQ A;  2DKQ A;  2YF0 A;  3PZD A;  3FM8 C;  4P7I A;  4Z2N A;  3TFM A;  3PP2 A;  1V61 A;  1NTY A;  1N3H A;  2M14 A;  3A8P A;  1Z87 A;  3PVW A;  1KZ7 A;  2NMB A;  2RSG A;  4ZRI A;  1ZC4 B;  2DKP A;  4MY6 A;  4WVF B;  2K2U A;  1MK9 B;  1Q67 A;  2P0F A;  3QIJ A;  4DBB A;  1ZC3 B;  3G9W A;  3BIN A;  3HK0 A;  1X1G A;  2UZR A;  4NY0 A;  4CHJ A;  3T06 A;  1SGH A;  1OQN A;  2Y8G A;  2YT1 A;  5D3V A;  1UNR A;  3U7D A;  2M38 A;  1RRP B;  3P7Z A;  1WJM A;  2KUP A;  3UZT A;  3ZDT A;  3KY9 A;  4EKU A;  4MT7 A;  2W2W A;  2MWN B;  2DHK A;  2K00 A;  5LON B;  4WSF A;  3D8D A;  2D4Q A;  1W1H A;  1I2H A;  1E5W A;  1P5T A;  5CLQ B;  2D10 A;  3AU5 A;  4F7H A;  1FGY A;  4BBK A;  1KI1 B;  2ROV A;  3DXD A;  1BTN A;  3SO6 A;  2X18 A;  1MPH A;  4HB2 B;  2RVB B;  4XWX A;  3V5W A;  2GJY A;  2GCJ A;  2W2X C;  4EMO A;  1KZG A;  1WGQ A;  3OAN A;  4DXA B;  1TJ6 A;  1ISN A;  5DHA B;  2YS1 A;  2CY5 A;  5L81 A;  5HE3 A;  1UPR A;  5DIF B;  2UVM A;  4MK0 A;  1GC6 A;  2J59 M;  2EC1 A;  1EVH A;  3KZ1 A;  4GMV A;  1FGZ A;  1EGX A;  1PMS A;  4IOY X;  2YS3 A;  2ROZ B;  2DYQ A;  4K81 A;  3SV1 A;  1XD4 A;  3KRX A;  1ZM0 A;  2D9Z A;  2R09 A;  2Y7B A;  2COF A;  1V89 A;  2P0H A;  2DYN A;  2DFK A;  3ULC A;  1DBH A;  3PVL A;  4IFS A;  1WGU A;  4L6E A;  1OMW A;  1ZVR A;  3MPX A;  4A6F A;  4KHO A;  2Z0O A;  3PVU A;  3GYP A;  1H4R A;  1I7A A;  2VRW B;  1W1G A;  5JP4 A;  4A6H A;  1P6S A;  3TCA A;  4Y94 A;  2RLO A;  1OY2 A;  2COD A;  2P8V A;  2MFQ A;  5DI9 B;  1V5M A;  2EMT A;  2R0D A;  3WA0 A;  3PG7 A;  3VIA A;  3NSU A;  1DYN A;  2P0D A;  1MAI A;  4HAW B;  2HTH B;  2IYB A;  2OQB A;  5HE2 A;  1NU2 A;  2J0K A;  5GOW B;  1BTK A;  2V76 A;  1U5D A;  2QKM A;  2I5F A;  1V5U A;  4F7G A;  1X86 A;  4H8S A;  1WJ1 A;  4HHV A; 
#chains in the Genus database with same CATH topology
 2ZPY A;  4KHA A;  3SNH A;  1J19 A;  3TW1 A;  3KSY A;  2DTC A;  3SUZ A;  3KRW A;  3AU4 A;  2NZ8 B;  2ELB A;  1DDW A;  1RJ2 A;  3ML4 A;  4K2P A;  5C5B A;  4HB4 B;  4CSQ A;  1FOE A;  2KCJ A;  2PZ1 A;  2R2Y A;  3QWM A;  2MKR A;  2DA0 A;  2I1K A;  3PEG A;  2VSZ A;  5D3W A;  5J3T A;  4HDO A;  2D9Y A;  3DXE A;  4QXA B;  1M7E A;  3NWA A;  1LW3 A;  5HE1 A;  3ULB A;  3U8Z A;  5J3Q A;  4GPT B;  2Z59 A;  1QQG A;  1UEF A;  1NTV A;  4PQ0 A;  3O96 A;  1DDV A;  5HE0 A;  4A5K A;  2YSZ A;  2N23 A;  3RCP A;  4OSN A;  2Z0P A;  2GUM A;  3LJU X;  3HIE A;  1XCG A;  4HSI A;  4CHM A;  2DHJ A;  5DHF B;  1U27 A;  2J0M A;  3OHM B;  4ZRK A;  4D0N B;  4PNK A;  1M7R A;  4DX8 A;  1DDM A;  5I2M A;  1U2B A;  2NBV A;  2LG1 A;  5J3Y A;  3QBV B;  2DN6 A;  5D3Y A;  5LG4 B;  1K5G B;  3DXC A;  2AL6 A;  1BAK A;  3A8Q A;  2RNR B;  1SHC A;  2LUL A;  2Q13 A;  1NI2 A;  5D3X A;  2Y8F A;  1Y19 B;  4HAU B;  2AEH A;  2CAY A;  2KGX B;  4A6F B;  2UZS A;  3IVF A;  3ODO A;  1W1D A;  4KHB B;  4GN1 A;  1FHO A;  3F0W A;  5C5B B;  2CY4 A;  2Z14 A;  2E2X A;  1P3R A;  2LKO A;  2ZKM X;  4F7U P;  1FB8 A;  2DLW A;  1MIX A;  2JP2 A;  1EF1 A;  1BWN A;  5C79 A;  2D2Q A;  1AQC A;  2XQN M;  1AWE A;  1ZSQ A;  1B55 A;  4HAV B;  5JHG A;  3HQC A;  5C6R A;  4GZU A;  2GS0 A;  3BJI A;  4D6W A;  1T77 A;  4Z2M B;  2RUK B;  4GNK B;  5IRS A;  4K17 A;  3ODW A;  5DH9 B;  1X11 A;  1MIZ B;  1UPQ A;  4QJ4 B;  4HAX B;  4C0A A;  4GXB A;  2DHI A;  5M4Y B;  1UNQ A;  2EMS A;  2HE7 A;  1Y5O A;  5FI1 A;  2COA A;  5D27 A;  4CYE A;  5KQ4 A;  3N7C A;  1TXD A;  4HB3 B;  3P6A A;  2DX1 A;  2ADZ A;  5JHH A;  3TVV A;  1V5P A;  1U5F A;  3CIK A;  1WVH A;  4KVG B;  2FJL A;  4GMX B;  2QKL A;  1J0W A;  1TQZ A;  4YON A;  3AJ4 A;  1GC7 A;  2D11 A;  1PFJ A;  4HAY B;  1DRO A;  2W2X D;  1XX0 A;  3B77 A;  1X05 A;  5CLL B;  2H7E A;  2COC A;  1MK7 B;  5JLJ B;  3FEH A;  2LOZ A;  5C16 A;  2EJ8 A;  1FHW A;  3TO1 A;  4ZRJ A;  2ELA A;  3CXB B;  3FSS A;  2YS5 A;  2CRF A;  2VKI A;  2N0Y A;  1MI1 A;  4HB0 B;  3ODX A;  2K8E A;  1U29 A;  1V88 A;  1QC6 A;  4KAX B;  3DCX A;  3NW8 A;  4HAZ B;  1FAO A;  4A6K A;  3NWD A;  4B6H A;  1XR0 B;  3SYX A;  1XKE A;  4K2O A;  2D9V A;  1XOD A;  3GYO A;  5LOP B;  5KCV A;  3M1I B;  2I1J A;  1X1F A;  1WG7 A;  2YRY A;  2J0J A;  1UNP A;  4WJ7 A;  2Z0Q A;  2KIG A;  5EFX A;  2D9X A;  1MKE A;  1LB1 A;  4HAT B;  3HW2 B;  2I5C A;  4OT1 A;  1U5E A;  1IRS A;  2RRF A;  2RGN B;  4NSW A;  3A98 B;  1GG3 A;  2L2I A;  2GCL A;  1ZYI A;  4EJN A;  1K5D B;  2BCJ A;  3MDB C;  3HSA A;  2YT0 A;  4TYZ A;  3D8E A;  2KUQ A;  1WI1 A;  3A58 A;  3D8F A;  1FHX A;  3WYF B;  2H7D A;  3PSC A;  3X23 A;  2L1C A;  2K49 A;  3VOQ A;  2YVC A;  1PLS A;  1H10 A;  4IAP A;  2IFS A;  1U5G A;  4DX9 0;  1EAZ A;  4YL8 A;  4TKN A;  5FI0 A;  3ZVR A;  2LOX A;  2D9W A;  3F5R A;  2LYD A;  2OTX A;  2K2J A;  5KQ1 A;  2DX5 A;  2MDX A;  2G35 A;  4HDQ A;  2DKQ A;  2YF0 A;  3PZD A;  3FM8 C;  4P7I A;  4Z2N A;  3TFM A;  3PP2 A;  1V61 A;  1NTY A;  1N3H A;  2M14 A;  3A8P A;  1Z87 A;  3PVW A;  1KZ7 A;  2NMB A;  2RSG A;  4ZRI A;  1ZC4 B;  2DKP A;  3FVC A;  4MY6 A;  4WVF B;  2K2U A;  1MK9 B;  1Q67 A;  2P0F A;  3QIJ A;  4DBB A;  1ZC3 B;  3G9W A;  3BIN A;  3HK0 A;  1X1G A;  2UZR A;  4NY0 A;  4CHJ A;  2KR0 A;  3T06 A;  1SGH A;  1OQN A;  2Y8G A;  2YT1 A;  5D3V A;  1UNR A;  3U7D A;  2M38 A;  1RRP B;  3P7Z A;  1WJM A;  2KUP A;  3UZT A;  3ZDT A;  3KY9 A;  4EKU A;  4MT7 A;  2W2W A;  2MWN B;  2DHK A;  2K00 A;  5LON B;  4WSF A;  3D8D A;  2D4Q A;  1W1H A;  1I2H A;  1E5W A;  1P5T A;  5CLQ B;  2D10 A;  3AU5 A;  4F7H A;  1FGY A;  4BBK A;  1KI1 B;  2ROV A;  3DXD A;  1BTN A;  3SO6 A;  2X18 A;  1MPH A;  4HB2 B;  2RVB B;  4XWX A;  3V5W A;  2GJY A;  2GCJ A;  2W2X C;  2Z13 A;  4EMO A;  1KZG A;  1WGQ A;  3OAN A;  2YT2 A;  4GOU A;  4DXA B;  1TJ6 A;  1ISN A;  5DHA B;  3NWF A;  2YS1 A;  2FJU B;  2CY5 A;  2Z4D A;  5L81 A;  5HE3 A;  1UPR A;  5DIF B;  2UVM A;  4MK0 A;  1GC6 A;  2J59 M;  2EC1 A;  1EVH A;  3KZ1 A;  4GMV A;  1FGZ A;  1EGX A;  2KIE A;  5I2S A;  1PMS A;  4IOY X;  2YS3 A;  2ROZ B;  2DYQ A;  4K81 A;  3SV1 A;  1XD4 A;  3KRX A;  1ZM0 A;  2D9Z A;  2R09 A;  2Y7B A;  2COF A;  1V89 A;  4QJ3 B;  2P0H A;  2DYN A;  2DFK A;  3ULC A;  1DBH A;  4QJ5 B;  4KHB A;  3PVL A;  4IFS A;  1WGU A;  4L6E A;  1OMW A;  1ZVR A;  3MPX A;  4A6F A;  4KHO A;  2Z0O A;  3PVU A;  3GYP A;  1H4R A;  1I7A A;  4L1R A;  2VRW B;  1W1G A;  5JP4 A;  4A6H A;  1P6S A;  3TCA A;  4Y94 A;  2RLO A;  1OY2 A;  2COD A;  2P8V A;  2MFQ A;  5DI9 B;  1V5M A;  2EMT A;  2R0D A;  3WA0 A;  3U12 A;  3PG7 A;  3VIA A;  3NSU A;  1DYN A;  2P0D A;  1MAI A;  4HAW B;  2HTH B;  2IYB A;  2OQB A;  5HE2 A;  1NU2 A;  2J0K A;  4DIX A;  5GOW B;  1BTK A;  2V76 A;  1U5D A;  2QKM A;  2I5F A;  1V5U A;  4F7G A;  1X86 A;  4H8S A;  1WJ1 A;  4HHV A; 
#chains in the Genus database with same CATH homology
 2ZPY A;  4KHA A;  3SNH A;  1J19 A;  3TW1 A;  3KSY A;  2DTC A;  3SUZ A;  3KRW A;  3AU4 A;  2NZ8 B;  2ELB A;  1DDW A;  1RJ2 A;  3ML4 A;  4K2P A;  5C5B A;  4HB4 B;  1FOE A;  2KCJ A;  2PZ1 A;  3QWM A;  2MKR A;  2DA0 A;  2I1K A;  3PEG A;  2VSZ A;  5D3W A;  5J3T A;  4HDO A;  2D9Y A;  3DXE A;  1M7E A;  3ULB A;  1LW3 A;  5HE1 A;  3U8Z A;  5J3Q A;  4GPT B;  1QQG A;  1UEF A;  1NTV A;  4PQ0 A;  3O96 A;  1DDV A;  5HE0 A;  4A5K A;  2YSZ A;  2N23 A;  3RCP A;  2Z0P A;  3LJU X;  1XCG A;  4CHM A;  2DHJ A;  5DHF B;  1U27 A;  2J0M A;  4ZRK A;  4D0N B;  4PNK A;  1M7R A;  4DX8 A;  1DDM A;  1U2B A;  2LG1 A;  5J3Y A;  3QBV B;  2DN6 A;  5D3Y A;  1K5G B;  3DXC A;  2AL6 A;  1BAK A;  3A8Q A;  2RNR B;  1SHC A;  2LUL A;  2Q13 A;  1NI2 A;  5D3X A;  2Y8F A;  1Y19 B;  4HAU B;  2AEH A;  2CAY A;  2KGX B;  4A6F B;  2UZS A;  3IVF A;  3ODO A;  1W1D A;  4KHB B;  4GN1 A;  1FHO A;  3F0W A;  5C5B B;  2CY4 A;  2E2X A;  1P3R A;  2LKO A;  4F7U P;  1FB8 A;  2DLW A;  1MIX A;  2JP2 A;  1EF1 A;  1BWN A;  5C79 A;  2D2Q A;  1AQC A;  2XQN M;  1AWE A;  1ZSQ A;  1B55 A;  4HAV B;  5JHG A;  3HQC A;  5C6R A;  4GZU A;  2GS0 A;  3BJI A;  4Z2M B;  2RUK B;  4K17 A;  3ODW A;  5DH9 B;  1X11 A;  1MIZ B;  1UPQ A;  4HAX B;  4C0A A;  4GXB A;  2DHI A;  1UNQ A;  2EMS A;  2HE7 A;  1Y5O A;  5FI1 A;  2COA A;  5D27 A;  4CYE A;  5KQ4 A;  3N7C A;  1TXD A;  4HB3 B;  3P6A A;  2DX1 A;  2ADZ A;  5JHH A;  3TVV A;  1V5P A;  1U5F A;  3CIK A;  1WVH A;  4KVG B;  2FJL A;  4GMX B;  2QKL A;  1J0W A;  1TQZ A;  4YON A;  3AJ4 A;  1GC7 A;  2D11 A;  1PFJ A;  4HAY B;  1DRO A;  2W2X D;  1XX0 A;  5CLL B;  1X05 A;  2H7E A;  2COC A;  1MK7 B;  5JLJ B;  3FEH A;  2LOZ A;  5C16 A;  2EJ8 A;  1FHW A;  3TO1 A;  4ZRJ A;  2ELA A;  3CXB B;  3FSS A;  2YS5 A;  2CRF A;  2VKI A;  2N0Y A;  4HB0 B;  3ODX A;  1U29 A;  1V88 A;  1QC6 A;  4KAX B;  4HAZ B;  1FAO A;  4A6K A;  4B6H A;  1XR0 B;  3SYX A;  1XKE A;  4K2O A;  2D9V A;  1XOD A;  3GYO A;  5LOP B;  5KCV A;  3M1I B;  2I1J A;  1X1F A;  1WG7 A;  2YRY A;  2J0J A;  1UNP A;  4WJ7 A;  2Z0Q A;  5EFX A;  2D9X A;  1MKE A;  1LB1 A;  4HAT B;  3HW2 B;  2I5C A;  1U5E A;  1IRS A;  2RGN B;  4NSW A;  3A98 B;  1GG3 A;  2L2I A;  2GCL A;  4EJN A;  1K5D B;  2BCJ A;  3MDB C;  2YT0 A;  4TYZ A;  3D8E A;  1WI1 A;  3D8F A;  1FHX A;  3WYF B;  2H7D A;  3PSC A;  3X23 A;  2L1C A;  3VOQ A;  2YVC A;  1PLS A;  1H10 A;  4IAP A;  2IFS A;  1U5G A;  4DX9 0;  1EAZ A;  4YL8 A;  4TKN A;  5FI0 A;  3ZVR A;  2LOX A;  2D9W A;  3F5R A;  2LYD A;  2OTX A;  2K2J A;  5KQ1 A;  2DX5 A;  2MDX A;  2G35 A;  4HDQ A;  2DKQ A;  2YF0 A;  3PZD A;  3FM8 C;  4P7I A;  4Z2N A;  3TFM A;  3PP2 A;  1V61 A;  1NTY A;  1N3H A;  2M14 A;  3A8P A;  1Z87 A;  3PVW A;  1KZ7 A;  2NMB A;  2RSG A;  4ZRI A;  1ZC4 B;  2DKP A;  4MY6 A;  4WVF B;  2K2U A;  1MK9 B;  1Q67 A;  2P0F A;  3QIJ A;  4DBB A;  1ZC3 B;  3G9W A;  3BIN A;  3HK0 A;  1X1G A;  2UZR A;  4NY0 A;  4CHJ A;  3T06 A;  1SGH A;  1OQN A;  2Y8G A;  2YT1 A;  5D3V A;  1UNR A;  3U7D A;  2M38 A;  1RRP B;  3P7Z A;  1WJM A;  2KUP A;  3UZT A;  3ZDT A;  3KY9 A;  4EKU A;  4MT7 A;  2W2W A;  2MWN B;  2DHK A;  2K00 A;  5LON B;  4WSF A;  3D8D A;  2D4Q A;  1W1H A;  1I2H A;  1E5W A;  1P5T A;  5CLQ B;  2D10 A;  3AU5 A;  4F7H A;  1FGY A;  4BBK A;  1KI1 B;  2ROV A;  3DXD A;  1BTN A;  3SO6 A;  2X18 A;  1MPH A;  4HB2 B;  2RVB B;  4XWX A;  3V5W A;  2GJY A;  2GCJ A;  2W2X C;  4EMO A;  1KZG A;  1WGQ A;  3OAN A;  4DXA B;  1TJ6 A;  1ISN A;  5DHA B;  2YS1 A;  2CY5 A;  5L81 A;  5HE3 A;  1UPR A;  5DIF B;  2UVM A;  4MK0 A;  1GC6 A;  2J59 M;  2EC1 A;  1EVH A;  3KZ1 A;  4GMV A;  1FGZ A;  1EGX A;  1PMS A;  4IOY X;  2YS3 A;  2ROZ B;  2DYQ A;  4K81 A;  3SV1 A;  1XD4 A;  3KRX A;  1ZM0 A;  2D9Z A;  2R09 A;  2Y7B A;  2COF A;  1V89 A;  2P0H A;  2DYN A;  2DFK A;  3ULC A;  1DBH A;  3PVL A;  4IFS A;  1WGU A;  4L6E A;  1OMW A;  1ZVR A;  3MPX A;  4A6F A;  4KHO A;  2Z0O A;  3PVU A;  3GYP A;  1H4R A;  1I7A A;  2VRW B;  1W1G A;  5JP4 A;  4A6H A;  1P6S A;  3TCA A;  4Y94 A;  2RLO A;  1OY2 A;  2COD A;  2P8V A;  2MFQ A;  5DI9 B;  1V5M A;  2EMT A;  2R0D A;  3WA0 A;  3PG7 A;  3VIA A;  3NSU A;  1DYN A;  2P0D A;  1MAI A;  4HAW B;  2HTH B;  2IYB A;  2OQB A;  5HE2 A;  1NU2 A;  2J0K A;  5GOW B;  1BTK A;  2V76 A;  1U5D A;  2QKM A;  2I5F A;  1V5U A;  4F7G A;  1X86 A;  4H8S A;  1WJ1 A;  4HHV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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