1M9DC

X-ray crystal structure of cyclophilin a/hiv-1 ca n-terminal domain (1-146) o-type chimera complex.
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
146
structure length
146
Chain Sequence
PIVQNLQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRTHPPAMGPLPPGQIREPRGSDIAGTTSTLQEQIGWMTHNPPIPVGEIYKRWIILGLNKIVRMYS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insights into the catalytic mechanism of cyclophilin A
pubmed doi rcsb
molecule tags Isomerase/viral protein
source organism Homo sapiens
molecule keywords Cyclophilin A
total genus 49
structure length 146
sequence length 146
chains with identical sequence D
ec nomenclature ec 2.7.7.49: RNA-directed DNA polymerase.
pdb deposition date 2002-07-28
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.375.10 Mainly Alpha Orthogonal Bundle Human Immunodeficiency Virus Type 1 Capsid Protein Human Immunodeficiency Virus Type 1 Capsid Protein 1m9dC00
4INBA 1EM9A 1EIAA 2M8LA 2GOLB 2PWMA 1E6JP 1M9DC 5HGMA 4XFXA 2KGFA 4NX4C 4QNBA 4HTWA 2LF4A 5HGNA 1AK4C 5JPAA 2V4XA 1AFVA 2XGUA 3P05A 3BP9A 4U0EA 1GWPA 2WLVB 2WLVA 2X82A 2Y4ZA 4PH3A 4PH2A 1G03A 4PH0A 2M8PA 1M9FC 1M9XC 3NTEA 4U0CA 2PXRC 5HGKA 4XROA 2PWOA 2XGYA 4WYMA 4DGAC 2X83A 4XFYA 4U0BA 1M9EC 2GONA 4DGEC 2XDEA 1QRJA 4XFZA 2JPRA 1U7KA 3MGEA 4LQWC 5HGOA 3H4EA 3H47A 4B4NA 1M9CC 4U0FA 2XGVA 2X2DD 4U0AA 5HGLA 1P7NA 4XRQA 2M8NA 1L6NA 2EIAA 1M9YC 4U0DA 4E91A 4J93A 1D1DA 4E92A
chains in the Genus database with same CATH superfamily
4INBA 1EM9A 1EIAA 2M8LA 2GOLB 2PWMA 1E6JP 1M9DC 5HGMA 4XFXA 2KGFA 4NX4C 4QNBA 4HTWA 2LF4A 5HGNA 1AK4C 5JPAA 2V4XA 1AFVA 2XGUA 3P05A 3BP9A 4U0EA 1GWPA 2WLVB 2WLVA 2X82A 2Y4ZA 4PH3A 4PH2A 1G03A 4PH0A 2M8PA 1M9FC 1M9XC 3NTEA 4U0CA 2PXRC 5HGKA 4XROA 2PWOA 2XGYA 4WYMA 4DGAC 2X83A 4XFYA 4U0BA 1M9EC 2GONA 4DGEC 2XDEA 1QRJA 4XFZA 2JPRA 1U7KA 3MGEA 4LQWC 5HGOA 3H4EA 3H47A 4B4NA 1M9CC 4U0FA 2XGVA 2X2DD 4U0AA 5HGLA 1P7NA 4XRQA 2M8NA 1L6NA 2EIAA 1M9YC 4U0DA 4E91A 4J93A 1D1DA 4E92A
chains in the Genus database with same CATH topology
4INBA 1EM9A 1EIAA 2M8LA 2GOLB 2PWMA 1E6JP 1M9DC 5HGMA 4XFXA 2KGFA 4NX4C 4QNBA 4HTWA 2LF4A 5HGNA 1AK4C 5JPAA 2V4XA 1AFVA 2XGUA 3P05A 3BP9A 4U0EA 1GWPA 2WLVB 2WLVA 2X82A 2Y4ZA 4PH3A 4PH2A 1G03A 4PH0A 2M8PA 1M9FC 1M9XC 3NTEA 4U0CA 2PXRC 5HGKA 4XROA 2PWOA 2XGYA 4WYMA 4DGAC 2X83A 4XFYA 4U0BA 1M9EC 2GONA 4DGEC 2XDEA 1QRJA 4XFZA 2JPRA 1U7KA 3MGEA 4LQWC 5HGOA 3H4EA 3H47A 4B4NA 1M9CC 4U0FA 2XGVA 2X2DD 4U0AA 5HGLA 1P7NA 4XRQA 2M8NA 1L6NA 2EIAA 1M9YC 4U0DA 4E91A 4J93A 1D1DA 4E92A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4INB A;  1EM9 A;  1EIA A;  2M8L A;  2GOL B;  2PWM A;  1E6J P;  1M9D C;  5HGM A;  4XFX A;  2KGF A;  4NX4 C;  4QNB A;  4HTW A;  2LF4 A;  5HGN A;  1AK4 C;  5JPA A;  2V4X A;  1AFV A;  2XGU A;  3P05 A;  3BP9 A;  4U0E A;  1GWP A;  2WLV B;  2WLV A;  2X82 A;  2Y4Z A;  4PH3 A;  4PH2 A;  1G03 A;  4PH0 A;  2M8P A;  1M9F C;  1M9X C;  3NTE A;  4U0C A;  2PXR C;  5HGK A;  4XRO A;  2PWO A;  2XGY A;  4WYM A;  4DGA C;  2X83 A;  4XFY A;  4U0B A;  1M9E C;  2GON A;  4DGE C;  2XDE A;  1QRJ A;  4XFZ A;  2JPR A;  1U7K A;  3MGE A;  4LQW C;  5HGO A;  3H4E A;  3H47 A;  4B4N A;  1M9C C;  4U0F A;  2XGV A;  2X2D D;  4U0A A;  5HGL A;  1P7N A;  4XRQ A;  2M8N A;  1L6N A;  2EIA A;  1M9Y C;  4U0D A;  4E91 A;  4J93 A;  1D1D A;  4E92 A; 
#chains in the Genus database with same CATH topology
 4INB A;  1EM9 A;  1EIA A;  2M8L A;  2GOL B;  2PWM A;  1E6J P;  1M9D C;  5HGM A;  4XFX A;  2KGF A;  4NX4 C;  4QNB A;  4HTW A;  2LF4 A;  5HGN A;  1AK4 C;  5JPA A;  2V4X A;  1AFV A;  2XGU A;  3P05 A;  3BP9 A;  4U0E A;  1GWP A;  2WLV B;  2WLV A;  2X82 A;  2Y4Z A;  4PH3 A;  4PH2 A;  1G03 A;  4PH0 A;  2M8P A;  1M9F C;  1M9X C;  3NTE A;  4U0C A;  2PXR C;  5HGK A;  4XRO A;  2PWO A;  2XGY A;  4WYM A;  4DGA C;  2X83 A;  4XFY A;  4U0B A;  1M9E C;  2GON A;  4DGE C;  2XDE A;  1QRJ A;  4XFZ A;  2JPR A;  1U7K A;  3MGE A;  4LQW C;  5HGO A;  3H4E A;  3H47 A;  4B4N A;  1M9C C;  4U0F A;  2XGV A;  2X2D D;  4U0A A;  5HGL A;  1P7N A;  4XRQ A;  2M8N A;  1L6N A;  2EIA A;  1M9Y C;  4U0D A;  4E91 A;  4J93 A;  1D1D A;  4E92 A; 
#chains in the Genus database with same CATH homology
 4INB A;  1EM9 A;  1EIA A;  2M8L A;  2GOL B;  2PWM A;  1E6J P;  1M9D C;  5HGM A;  4XFX A;  2KGF A;  4NX4 C;  4QNB A;  4HTW A;  2LF4 A;  5HGN A;  1AK4 C;  5JPA A;  2V4X A;  1AFV A;  2XGU A;  3P05 A;  3BP9 A;  4U0E A;  1GWP A;  2WLV B;  2WLV A;  2X82 A;  2Y4Z A;  4PH3 A;  4PH2 A;  1G03 A;  4PH0 A;  2M8P A;  1M9F C;  1M9X C;  3NTE A;  4U0C A;  2PXR C;  5HGK A;  4XRO A;  2PWO A;  2XGY A;  4WYM A;  4DGA C;  2X83 A;  4XFY A;  4U0B A;  1M9E C;  2GON A;  4DGE C;  2XDE A;  1QRJ A;  4XFZ A;  2JPR A;  1U7K A;  3MGE A;  4LQW C;  5HGO A;  3H4E A;  3H47 A;  4B4N A;  1M9C C;  4U0F A;  2XGV A;  2X2D D;  4U0A A;  5HGL A;  1P7N A;  4XRQ A;  2M8N A;  1L6N A;  2EIA A;  1M9Y C;  4U0D A;  4E91 A;  4J93 A;  1D1D A;  4E92 A; 
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similar chains in the pdb database (?% sequence similarity)

 
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