1M9EC

X-ray crystal structure of cyclophilin a/hiv-1 ca n-terminal domain (1-146) m-type h87a complex.
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
146
structure length
146
Chain Sequence
PIVQNLQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVAAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTHNPPIPVGEIYKRWIILGLNKIVRMYS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insights into the catalytic mechanism of cyclophilin A
pubmed doi rcsb
molecule tags Isomerase/viral protein
source organism Homo sapiens
molecule keywords Cyclophilin A
total genus 50
structure length 146
sequence length 146
chains with identical sequence D
ec nomenclature
pdb deposition date 2002-07-28
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.375.10 Mainly Alpha Orthogonal Bundle Human Immunodeficiency Virus Type 1 Capsid Protein Human Immunodeficiency Virus Type 1 Capsid Protein 1m9eC00
2X83A 4U0FA 1EM9A 4NX4C 3P05A 1P7NA 3H4EA 1G03A 1M9EC 2XGUA 4XRQA 4E91A 2M8PA 1E6JP 1M9DC 1D1DA 4XFZA 3BP9A 2V4XA 2WLVB 2KGFA 4HTWA 4PH2A 4U0AA 2XGVA 1QRJA 1AFVA 4U0EA 2X82A 2GONA 1M9YC 4QNBA 2Y4ZA 1M9FC 5JPAA 3NTEA 5HGNA 2GOLB 2WLVA 1GWPA 2LF4A 4INBA 2XDEA 4XROA 5HGKA 2X2DD 1M9XC 2XGYA 4U0BA 4XFYA 4DGAC 1AK4C 4J93A 1EIAA 2PXRC 2JPRA 1U7KA 4E92A 2PWOA 4PH0A 2M8LA 4WYMA 2M8NA 4PH3A 4DGEC 4U0DA 1M9CC 5HGLA 4U0CA 3H47A 2PWMA 4B4NA 5HGMA 4LQWC 5HGOA 1L6NA 4XFXA 2EIAA 3MGEA
chains in the Genus database with same CATH superfamily
2X83A 4U0FA 1EM9A 4NX4C 3P05A 1P7NA 3H4EA 1G03A 1M9EC 2XGUA 4XRQA 4E91A 2M8PA 1E6JP 1M9DC 1D1DA 4XFZA 3BP9A 2V4XA 2WLVB 2KGFA 4HTWA 4PH2A 4U0AA 2XGVA 1QRJA 1AFVA 4U0EA 2X82A 2GONA 1M9YC 4QNBA 2Y4ZA 1M9FC 5JPAA 3NTEA 5HGNA 2GOLB 2WLVA 1GWPA 2LF4A 4INBA 2XDEA 4XROA 5HGKA 2X2DD 1M9XC 2XGYA 4U0BA 4XFYA 4DGAC 1AK4C 4J93A 1EIAA 2PXRC 2JPRA 1U7KA 4E92A 2PWOA 4PH0A 2M8LA 4WYMA 2M8NA 4PH3A 4DGEC 4U0DA 1M9CC 5HGLA 4U0CA 3H47A 2PWMA 4B4NA 5HGMA 4LQWC 5HGOA 1L6NA 4XFXA 2EIAA 3MGEA
chains in the Genus database with same CATH topology
2X83A 4U0FA 1EM9A 4NX4C 3P05A 1P7NA 3H4EA 1G03A 1M9EC 2XGUA 4XRQA 4E91A 2M8PA 1E6JP 1M9DC 1D1DA 4XFZA 3BP9A 2V4XA 2WLVB 2KGFA 4HTWA 4PH2A 4U0AA 2XGVA 1QRJA 1AFVA 4U0EA 2X82A 2GONA 1M9YC 4QNBA 2Y4ZA 1M9FC 5JPAA 3NTEA 5HGNA 2GOLB 2WLVA 1GWPA 2LF4A 4INBA 2XDEA 4XROA 5HGKA 2X2DD 1M9XC 2XGYA 4U0BA 4XFYA 4DGAC 1AK4C 4J93A 1EIAA 2PXRC 2JPRA 1U7KA 4E92A 2PWOA 4PH0A 2M8LA 4WYMA 2M8NA 4PH3A 4DGEC 4U0DA 1M9CC 5HGLA 4U0CA 3H47A 2PWMA 4B4NA 5HGMA 4LQWC 5HGOA 1L6NA 4XFXA 2EIAA 3MGEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2X83 A;  4U0F A;  1EM9 A;  4NX4 C;  3P05 A;  1P7N A;  3H4E A;  1G03 A;  1M9E C;  2XGU A;  4XRQ A;  4E91 A;  2M8P A;  1E6J P;  1M9D C;  1D1D A;  4XFZ A;  3BP9 A;  2V4X A;  2WLV B;  2KGF A;  4HTW A;  4PH2 A;  4U0A A;  2XGV A;  1QRJ A;  1AFV A;  4U0E A;  2X82 A;  2GON A;  1M9Y C;  4QNB A;  2Y4Z A;  1M9F C;  5JPA A;  3NTE A;  5HGN A;  2GOL B;  2WLV A;  1GWP A;  2LF4 A;  4INB A;  2XDE A;  4XRO A;  5HGK A;  2X2D D;  1M9X C;  2XGY A;  4U0B A;  4XFY A;  4DGA C;  1AK4 C;  4J93 A;  1EIA A;  2PXR C;  2JPR A;  1U7K A;  4E92 A;  2PWO A;  4PH0 A;  2M8L A;  4WYM A;  2M8N A;  4PH3 A;  4DGE C;  4U0D A;  1M9C C;  5HGL A;  4U0C A;  3H47 A;  2PWM A;  4B4N A;  5HGM A;  4LQW C;  5HGO A;  1L6N A;  4XFX A;  2EIA A;  3MGE A; 
#chains in the Genus database with same CATH topology
 2X83 A;  4U0F A;  1EM9 A;  4NX4 C;  3P05 A;  1P7N A;  3H4E A;  1G03 A;  1M9E C;  2XGU A;  4XRQ A;  4E91 A;  2M8P A;  1E6J P;  1M9D C;  1D1D A;  4XFZ A;  3BP9 A;  2V4X A;  2WLV B;  2KGF A;  4HTW A;  4PH2 A;  4U0A A;  2XGV A;  1QRJ A;  1AFV A;  4U0E A;  2X82 A;  2GON A;  1M9Y C;  4QNB A;  2Y4Z A;  1M9F C;  5JPA A;  3NTE A;  5HGN A;  2GOL B;  2WLV A;  1GWP A;  2LF4 A;  4INB A;  2XDE A;  4XRO A;  5HGK A;  2X2D D;  1M9X C;  2XGY A;  4U0B A;  4XFY A;  4DGA C;  1AK4 C;  4J93 A;  1EIA A;  2PXR C;  2JPR A;  1U7K A;  4E92 A;  2PWO A;  4PH0 A;  2M8L A;  4WYM A;  2M8N A;  4PH3 A;  4DGE C;  4U0D A;  1M9C C;  5HGL A;  4U0C A;  3H47 A;  2PWM A;  4B4N A;  5HGM A;  4LQW C;  5HGO A;  1L6N A;  4XFX A;  2EIA A;  3MGE A; 
#chains in the Genus database with same CATH homology
 2X83 A;  4U0F A;  1EM9 A;  4NX4 C;  3P05 A;  1P7N A;  3H4E A;  1G03 A;  1M9E C;  2XGU A;  4XRQ A;  4E91 A;  2M8P A;  1E6J P;  1M9D C;  1D1D A;  4XFZ A;  3BP9 A;  2V4X A;  2WLV B;  2KGF A;  4HTW A;  4PH2 A;  4U0A A;  2XGV A;  1QRJ A;  1AFV A;  4U0E A;  2X82 A;  2GON A;  1M9Y C;  4QNB A;  2Y4Z A;  1M9F C;  5JPA A;  3NTE A;  5HGN A;  2GOL B;  2WLV A;  1GWP A;  2LF4 A;  4INB A;  2XDE A;  4XRO A;  5HGK A;  2X2D D;  1M9X C;  2XGY A;  4U0B A;  4XFY A;  4DGA C;  1AK4 C;  4J93 A;  1EIA A;  2PXR C;  2JPR A;  1U7K A;  4E92 A;  2PWO A;  4PH0 A;  2M8L A;  4WYM A;  2M8N A;  4PH3 A;  4DGE C;  4U0D A;  1M9C C;  5HGL A;  4U0C A;  3H47 A;  2PWM A;  4B4N A;  5HGM A;  4LQW C;  5HGO A;  1L6N A;  4XFX A;  2EIA A;  3MGE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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