1M9XC

X-ray crystal structure of cyclophilin a/hiv-1 ca n-terminal domain (1-146) m-type h87a,a88m,g89a complex.
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
146
structure length
146
Chain Sequence
PIVQNLQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVAMAPIAPGQMREPRGSDIAGTTSTLQEQIGWMTHNPPIPVGEIYKRWIILGLNKIVRMYS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insights into the catalytic mechanism of cyclophilin A
pubmed doi rcsb
molecule tags Isomerase/viral protein
source organism Homo sapiens
molecule keywords Cyclophilin A
total genus 50
structure length 146
sequence length 146
chains with identical sequence D, G, H
ec nomenclature
pdb deposition date 2002-07-30
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.375.10 Mainly Alpha Orthogonal Bundle Human Immunodeficiency Virus Type 1 Capsid Protein Human Immunodeficiency Virus Type 1 Capsid Protein 1m9xC00
5HGKA 4XRQA 2WLVA 4U0FA 2WLVB 2GOLB 4E91A 2X83A 1M9EC 1QRJA 1U7KA 4INBA 4DGEC 2GONA 3H47A 4XFZA 1AFVA 1GWPA 4XFXA 4PH2A 4XROA 1M9FC 4QNBA 4DGAC 4U0AA 4WYMA 4PH0A 2JPRA 1M9YC 4NX4C 4E92A 2LF4A 5HGMA 5JPAA 4U0BA 4HTWA 1M9XC 1AK4C 1P7NA 2XDEA 2M8PA 5HGNA 1E6JP 4XFYA 2V4XA 3NTEA 2Y4ZA 2PXRC 1D1DA 1EIAA 2XGYA 2XGVA 4J93A 2X82A 2KGFA 3BP9A 2M8LA 4LQWC 4PH3A 3H4EA 2EIAA 5HGLA 1M9CC 1M9DC 3MGEA 2XGUA 1G03A 2M8NA 3P05A 2X2DD 2PWOA 1EM9A 2PWMA 4U0EA 4B4NA 1L6NA 4U0CA 5HGOA 4U0DA
chains in the Genus database with same CATH superfamily
5HGKA 4XRQA 2WLVA 4U0FA 2WLVB 2GOLB 4E91A 2X83A 1M9EC 1QRJA 1U7KA 4INBA 4DGEC 2GONA 3H47A 4XFZA 1AFVA 1GWPA 4XFXA 4PH2A 4XROA 1M9FC 4QNBA 4DGAC 4U0AA 4WYMA 4PH0A 2JPRA 1M9YC 4NX4C 4E92A 2LF4A 5HGMA 5JPAA 4U0BA 4HTWA 1M9XC 1AK4C 1P7NA 2XDEA 2M8PA 5HGNA 1E6JP 4XFYA 2V4XA 3NTEA 2Y4ZA 2PXRC 1D1DA 1EIAA 2XGYA 2XGVA 4J93A 2X82A 2KGFA 3BP9A 2M8LA 4LQWC 4PH3A 3H4EA 2EIAA 5HGLA 1M9CC 1M9DC 3MGEA 2XGUA 1G03A 2M8NA 3P05A 2X2DD 2PWOA 1EM9A 2PWMA 4U0EA 4B4NA 1L6NA 4U0CA 5HGOA 4U0DA
chains in the Genus database with same CATH topology
5HGKA 4XRQA 2WLVA 4U0FA 2WLVB 2GOLB 4E91A 2X83A 1M9EC 1QRJA 1U7KA 4INBA 4DGEC 2GONA 3H47A 4XFZA 1AFVA 1GWPA 4XFXA 4PH2A 4XROA 1M9FC 4QNBA 4DGAC 4U0AA 4WYMA 4PH0A 2JPRA 1M9YC 4NX4C 4E92A 2LF4A 5HGMA 5JPAA 4U0BA 4HTWA 1M9XC 1AK4C 1P7NA 2XDEA 2M8PA 5HGNA 1E6JP 4XFYA 2V4XA 3NTEA 2Y4ZA 2PXRC 1D1DA 1EIAA 2XGYA 2XGVA 4J93A 2X82A 2KGFA 3BP9A 2M8LA 4LQWC 4PH3A 3H4EA 2EIAA 5HGLA 1M9CC 1M9DC 3MGEA 2XGUA 1G03A 2M8NA 3P05A 2X2DD 2PWOA 1EM9A 2PWMA 4U0EA 4B4NA 1L6NA 4U0CA 5HGOA 4U0DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5HGK A;  4XRQ A;  2WLV A;  4U0F A;  2WLV B;  2GOL B;  4E91 A;  2X83 A;  1M9E C;  1QRJ A;  1U7K A;  4INB A;  4DGE C;  2GON A;  3H47 A;  4XFZ A;  1AFV A;  1GWP A;  4XFX A;  4PH2 A;  4XRO A;  1M9F C;  4QNB A;  4DGA C;  4U0A A;  4WYM A;  4PH0 A;  2JPR A;  1M9Y C;  4NX4 C;  4E92 A;  2LF4 A;  5HGM A;  5JPA A;  4U0B A;  4HTW A;  1M9X C;  1AK4 C;  1P7N A;  2XDE A;  2M8P A;  5HGN A;  1E6J P;  4XFY A;  2V4X A;  3NTE A;  2Y4Z A;  2PXR C;  1D1D A;  1EIA A;  2XGY A;  2XGV A;  4J93 A;  2X82 A;  2KGF A;  3BP9 A;  2M8L A;  4LQW C;  4PH3 A;  3H4E A;  2EIA A;  5HGL A;  1M9C C;  1M9D C;  3MGE A;  2XGU A;  1G03 A;  2M8N A;  3P05 A;  2X2D D;  2PWO A;  1EM9 A;  2PWM A;  4U0E A;  4B4N A;  1L6N A;  4U0C A;  5HGO A;  4U0D A; 
#chains in the Genus database with same CATH topology
 5HGK A;  4XRQ A;  2WLV A;  4U0F A;  2WLV B;  2GOL B;  4E91 A;  2X83 A;  1M9E C;  1QRJ A;  1U7K A;  4INB A;  4DGE C;  2GON A;  3H47 A;  4XFZ A;  1AFV A;  1GWP A;  4XFX A;  4PH2 A;  4XRO A;  1M9F C;  4QNB A;  4DGA C;  4U0A A;  4WYM A;  4PH0 A;  2JPR A;  1M9Y C;  4NX4 C;  4E92 A;  2LF4 A;  5HGM A;  5JPA A;  4U0B A;  4HTW A;  1M9X C;  1AK4 C;  1P7N A;  2XDE A;  2M8P A;  5HGN A;  1E6J P;  4XFY A;  2V4X A;  3NTE A;  2Y4Z A;  2PXR C;  1D1D A;  1EIA A;  2XGY A;  2XGV A;  4J93 A;  2X82 A;  2KGF A;  3BP9 A;  2M8L A;  4LQW C;  4PH3 A;  3H4E A;  2EIA A;  5HGL A;  1M9C C;  1M9D C;  3MGE A;  2XGU A;  1G03 A;  2M8N A;  3P05 A;  2X2D D;  2PWO A;  1EM9 A;  2PWM A;  4U0E A;  4B4N A;  1L6N A;  4U0C A;  5HGO A;  4U0D A; 
#chains in the Genus database with same CATH homology
 5HGK A;  4XRQ A;  2WLV A;  4U0F A;  2WLV B;  2GOL B;  4E91 A;  2X83 A;  1M9E C;  1QRJ A;  1U7K A;  4INB A;  4DGE C;  2GON A;  3H47 A;  4XFZ A;  1AFV A;  1GWP A;  4XFX A;  4PH2 A;  4XRO A;  1M9F C;  4QNB A;  4DGA C;  4U0A A;  4WYM A;  4PH0 A;  2JPR A;  1M9Y C;  4NX4 C;  4E92 A;  2LF4 A;  5HGM A;  5JPA A;  4U0B A;  4HTW A;  1M9X C;  1AK4 C;  1P7N A;  2XDE A;  2M8P A;  5HGN A;  1E6J P;  4XFY A;  2V4X A;  3NTE A;  2Y4Z A;  2PXR C;  1D1D A;  1EIA A;  2XGY A;  2XGV A;  4J93 A;  2X82 A;  2KGF A;  3BP9 A;  2M8L A;  4LQW C;  4PH3 A;  3H4E A;  2EIA A;  5HGL A;  1M9C C;  1M9D C;  3MGE A;  2XGU A;  1G03 A;  2M8N A;  3P05 A;  2X2D D;  2PWO A;  1EM9 A;  2PWM A;  4U0E A;  4B4N A;  1L6N A;  4U0C A;  5HGO A;  4U0D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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