1MATA

Structure of the cobalt-dependent methionine aminopeptidase from escherichia coli: a new type of proteolytic enzyme
Total Genus 77
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
sequence length
263
structure length
263
Chain Sequence
AISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGRGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHDE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the cobalt-dependent methionine aminopeptidase from Escherichia coli: a new type of proteolytic enzyme.
pubmed doi rcsb
molecule tags Hydrolase(alpha-aminoacylpeptide)
source organism Escherichia coli
molecule keywords METHIONYL AMINOPEPTIDASE
total genus 77
structure length 263
sequence length 263
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 1992-12-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1matA00
3CB6A 1YW8A 4ZWOA 2BWXA 1BOAA 2Q8KA 2BHBA 2EA4A 4FO8A 3FMRA 5CE6A 4U6WA 2GU6A 3FM3A 2BWTA 2P9AA 1KP0A 1Y1NA 3L24A 1WY2A 4HXXA 5JI6A 4U69A 3BIPA 3FMQA 1XGSA 1WBQA 3PKDA 4FLJA 1CHMA 5FCHA 4FLKA 4ZWPA 2BWWA 5CDEA 3CB5A 5E5BA 4A6VA 2GTXA 1BN5A 4U6ZA 1XGNA 3MATA 2GG7A 2BB7A 2OKNA 2EVCA 4RZZA 2V3ZA 4U73A 2DFIA 2NQ6A 1C24A 2GG5A 2V6CA 3TB5A 1M35A 2MATA 2Q92A 3MR1A 4IDYA 4B28A 4FLLA 1QZYA 4FO7A 1PV9A 1YW9A 1C27A 4S2TP 2BHDA 4U76A 2BHCA 3RORA 2V3YA 3IU9A 4IF7A 5D6FA 1C23A 4U6CA 4S01A 1YW7A 1MATA 4R60A 4JUQA 1R5GA 4IKTA 4RGZ1 4Z7MA 4U75A 5JFRA 5D6EA 2GGBA 3D27A 4ZWUA 3PKAA 3RVAA 2EVMA 2BN7A 1JAWA 1WL9A 1QXWA 3IU8A 3PKBA 4FKCA 4U71A 1KQ9A 2EVOA 2GG2A 2GZ5A 2GGCA 2B3HA 2NQ7A 2ZSGA 4U1BA 3MX6A 5CIKA 1QXYA 3PKCA 1B6AA 2P98A 4U70A 2B3KA 2BWVA 2ADUA 4S2RP 3IG4A 1XGOA 1R58A 2GG3A 1WL6A 1YVMA 2EA2A 1C21A 2B3LA 4FLIA 5CDLA 1W2MA 2BWYA 1XNZA 2Q96A 2GG0A 4FUKA 1C22A 1WN1A 2GA2A 2IW2A 4A6WA 2V3XA 4QR8A 4KM3A 1O0XA 1WLRA 5CLSA 1A16A 1YJ3A 3L7GA 4IECA 4IU6A 5CDVA 4PNCA 5JHUA 3Q6DA 4U6EA 1KQ0A 1W7VA 4IKSA 4RZYA 2GG8A 2P99A 4S00A 2Q94A 4EGEA 2GU5A 3TAVA 2G6PA 3IU7A 3BITA 1N51A 1B59A 3CTZA 1QXZA 2BHAA 2GG9A 4MATA 3BIQA 2BH3A 4IKRA 4IKUA 4OOKA 1XGMA 4IPAA 1WKMA 2GU7A 2HOWA 5FCFA 3PKEA 2Q93A 2Q95A 3S6BA 2BWSA 2OAZA 4U6JA 2BWUA 2GU4A 5CNXA 1R5HA 4PV4A 4ZNGA
chains in the Genus database with same CATH superfamily
3CB6A 1YW8A 4ZWOA 2BWXA 1BOAA 2Q8KA 2BHBA 2EA4A 4FO8A 3FMRA 5CE6A 4U6WA 2GU6A 3FM3A 2BWTA 2P9AA 1KP0A 1Y1NA 3L24A 1WY2A 4HXXA 5JI6A 4U69A 3BIPA 3FMQA 1XGSA 1WBQA 3PKDA 4FLJA 1CHMA 5FCHA 4FLKA 4ZWPA 2BWWA 5CDEA 3CB5A 5E5BA 4A6VA 2GTXA 1BN5A 4U6ZA 1XGNA 3MATA 2GG7A 2BB7A 2OKNA 2EVCA 4RZZA 2V3ZA 4U73A 2DFIA 2NQ6A 1C24A 2GG5A 2V6CA 3TB5A 1M35A 2MATA 2Q92A 3MR1A 4IDYA 4B28A 4FLLA 1QZYA 4FO7A 1PV9A 1YW9A 1C27A 4S2TP 2BHDA 4U76A 2BHCA 3RORA 2V3YA 3IU9A 4IF7A 5D6FA 1C23A 4U6CA 4S01A 1YW7A 1MATA 4R60A 4JUQA 1R5GA 4IKTA 4RGZ1 4Z7MA 4U75A 5JFRA 5D6EA 2GGBA 3D27A 4ZWUA 3PKAA 3RVAA 2EVMA 2BN7A 1JAWA 1WL9A 1QXWA 3IU8A 3PKBA 4FKCA 4U71A 1KQ9A 2EVOA 2GG2A 2GZ5A 2GGCA 2B3HA 2NQ7A 2ZSGA 4U1BA 3MX6A 5CIKA 1QXYA 3PKCA 1B6AA 2P98A 4U70A 2B3KA 2BWVA 2ADUA 4S2RP 3IG4A 1XGOA 1R58A 2GG3A 1WL6A 1YVMA 2EA2A 1C21A 2B3LA 4FLIA 5CDLA 1W2MA 2BWYA 1XNZA 2Q96A 2GG0A 4FUKA 1C22A 1WN1A 2GA2A 2IW2A 4A6WA 2V3XA 4QR8A 4KM3A 1O0XA 1WLRA 5CLSA 1A16A 1YJ3A 3L7GA 4IECA 4IU6A 5CDVA 4PNCA 5JHUA 3Q6DA 4U6EA 1KQ0A 1W7VA 4IKSA 4RZYA 2GG8A 2P99A 4S00A 2Q94A 4EGEA 2GU5A 3TAVA 2G6PA 3IU7A 3BITA 1N51A 1B59A 3CTZA 1QXZA 2BHAA 2GG9A 4MATA 3BIQA 2BH3A 4IKRA 4IKUA 4OOKA 1XGMA 4IPAA 1WKMA 2GU7A 2HOWA 5FCFA 3PKEA 2Q93A 2Q95A 3S6BA 2BWSA 2OAZA 4U6JA 2BWUA 2GU4A 5CNXA 1R5HA 4PV4A 4ZNGA
chains in the Genus database with same CATH topology
3CB6A 1YW8A 4ZWOA 2BWXA 1BOAA 2Q8KA 2BHBA 2EA4A 4FO8A 3FMRA 5CE6A 4U6WA 2GU6A 3FM3A 2BWTA 2P9AA 1KP0A 1Y1NA 3L24A 1WY2A 4HXXA 5JI6A 4U69A 3BIPA 3FMQA 1XGSA 1WBQA 3PKDA 4FLJA 1CHMA 5FCHA 4FLKA 4ZWPA 2BWWA 5CDEA 3CB5A 5E5BA 4A6VA 2GTXA 1BN5A 4U6ZA 1XGNA 3MATA 2GG7A 2BB7A 2OKNA 2EVCA 4RZZA 2V3ZA 4U73A 2DFIA 2NQ6A 1C24A 2GG5A 2V6CA 3TB5A 1M35A 2MATA 2Q92A 3MR1A 4IDYA 4B28A 4FLLA 1QZYA 4FO7A 1PV9A 1YW9A 1C27A 4S2TP 2BHDA 4U76A 2BHCA 3RORA 2V3YA 3IU9A 4IF7A 5D6FA 1C23A 4U6CA 4S01A 1YW7A 1MATA 4R60A 4JUQA 1R5GA 4IKTA 4RGZ1 4Z7MA 4U75A 5JFRA 5D6EA 2GGBA 3D27A 4ZWUA 3PKAA 3RVAA 2EVMA 2BN7A 1JAWA 1WL9A 1QXWA 3IU8A 3PKBA 4FKCA 4U71A 1KQ9A 2EVOA 2GG2A 2GZ5A 2GGCA 2B3HA 2NQ7A 2ZSGA 4U1BA 3MX6A 5CIKA 1QXYA 3PKCA 1B6AA 2P98A 4U70A 2B3KA 2BWVA 2ADUA 4S2RP 3IG4A 1XGOA 1R58A 2GG3A 1WL6A 1YVMA 2EA2A 1C21A 2B3LA 4FLIA 5CDLA 1W2MA 2BWYA 1XNZA 2Q96A 2GG0A 4FUKA 1C22A 1WN1A 2GA2A 2IW2A 4A6WA 2V3XA 4QR8A 4KM3A 1O0XA 1WLRA 5CLSA 1A16A 1YJ3A 3L7GA 4IECA 4IU6A 5CDVA 4PNCA 5JHUA 3Q6DA 4U6EA 1KQ0A 1W7VA 4IKSA 4RZYA 2GG8A 2P99A 4S00A 2Q94A 4EGEA 2GU5A 3TAVA 2G6PA 3IU7A 3BITA 1N51A 1B59A 3CTZA 1QXZA 2BHAA 2GG9A 4MATA 3BIQA 2BH3A 4IKRA 4IKUA 4OOKA 1XGMA 4IPAA 1WKMA 2GU7A 2HOWA 5FCFA 3PKEA 2Q93A 2Q95A 3S6BA 2BWSA 2OAZA 4U6JA 2BWUA 2GU4A 5CNXA 1R5HA 4PV4A 4ZNGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CB6 A;  1YW8 A;  4ZWO A;  2BWX A;  1BOA A;  2Q8K A;  2BHB A;  2EA4 A;  4FO8 A;  3FMR A;  5CE6 A;  4U6W A;  2GU6 A;  3FM3 A;  2BWT A;  2P9A A;  1KP0 A;  1Y1N A;  3L24 A;  1WY2 A;  4HXX A;  5JI6 A;  4U69 A;  3BIP A;  3FMQ A;  1XGS A;  1WBQ A;  3PKD A;  4FLJ A;  1CHM A;  5FCH A;  4FLK A;  4ZWP A;  2BWW A;  5CDE A;  3CB5 A;  5E5B A;  4A6V A;  2GTX A;  1BN5 A;  4U6Z A;  1XGN A;  3MAT A;  2GG7 A;  2BB7 A;  2OKN A;  2EVC A;  4RZZ A;  2V3Z A;  4U73 A;  2DFI A;  2NQ6 A;  1C24 A;  2GG5 A;  2V6C A;  3TB5 A;  1M35 A;  2MAT A;  2Q92 A;  3MR1 A;  4IDY A;  4B28 A;  4FLL A;  1QZY A;  4FO7 A;  1PV9 A;  1YW9 A;  1C27 A;  4S2T P;  2BHD A;  4U76 A;  2BHC A;  3ROR A;  2V3Y A;  3IU9 A;  4IF7 A;  5D6F A;  1C23 A;  4U6C A;  4S01 A;  1YW7 A;  1MAT A;  4R60 A;  4JUQ A;  1R5G A;  4IKT A;  4RGZ 1;  4Z7M A;  4U75 A;  5JFR A;  5D6E A;  2GGB A;  3D27 A;  4ZWU A;  3PKA A;  3RVA A;  2EVM A;  2BN7 A;  1JAW A;  1WL9 A;  1QXW A;  3IU8 A;  3PKB A;  4FKC A;  4U71 A;  1KQ9 A;  2EVO A;  2GG2 A;  2GZ5 A;  2GGC A;  2B3H A;  2NQ7 A;  2ZSG A;  4U1B A;  3MX6 A;  5CIK A;  1QXY A;  3PKC A;  1B6A A;  2P98 A;  4U70 A;  2B3K A;  2BWV A;  2ADU A;  4S2R P;  3IG4 A;  1XGO A;  1R58 A;  2GG3 A;  1WL6 A;  1YVM A;  2EA2 A;  1C21 A;  2B3L A;  4FLI A;  5CDL A;  1W2M A;  2BWY A;  1XNZ A;  2Q96 A;  2GG0 A;  4FUK A;  1C22 A;  1WN1 A;  2GA2 A;  2IW2 A;  4A6W A;  2V3X A;  4QR8 A;  4KM3 A;  1O0X A;  1WLR A;  5CLS A;  1A16 A;  1YJ3 A;  3L7G A;  4IEC A;  4IU6 A;  5CDV A;  4PNC A;  5JHU A;  3Q6D A;  4U6E A;  1KQ0 A;  1W7V A;  4IKS A;  4RZY A;  2GG8 A;  2P99 A;  4S00 A;  2Q94 A;  4EGE A;  2GU5 A;  3TAV A;  2G6P A;  3IU7 A;  3BIT A;  1N51 A;  1B59 A;  3CTZ A;  1QXZ A;  2BHA A;  2GG9 A;  4MAT A;  3BIQ A;  2BH3 A;  4IKR A;  4IKU A;  4OOK A;  1XGM A;  4IPA A;  1WKM A;  2GU7 A;  2HOW A;  5FCF A;  3PKE A;  2Q93 A;  2Q95 A;  3S6B A;  2BWS A;  2OAZ A;  4U6J A;  2BWU A;  2GU4 A;  5CNX A;  1R5H A;  4PV4 A;  4ZNG A; 
#chains in the Genus database with same CATH topology
 3CB6 A;  1YW8 A;  4ZWO A;  2BWX A;  1BOA A;  2Q8K A;  2BHB A;  2EA4 A;  4FO8 A;  3FMR A;  5CE6 A;  4U6W A;  2GU6 A;  3FM3 A;  2BWT A;  2P9A A;  1KP0 A;  1Y1N A;  3L24 A;  1WY2 A;  4HXX A;  5JI6 A;  4U69 A;  3BIP A;  3FMQ A;  1XGS A;  1WBQ A;  3PKD A;  4FLJ A;  1CHM A;  5FCH A;  4FLK A;  4ZWP A;  2BWW A;  5CDE A;  3CB5 A;  5E5B A;  4A6V A;  2GTX A;  1BN5 A;  4U6Z A;  1XGN A;  3MAT A;  2GG7 A;  2BB7 A;  2OKN A;  2EVC A;  4RZZ A;  2V3Z A;  4U73 A;  2DFI A;  2NQ6 A;  1C24 A;  2GG5 A;  2V6C A;  3TB5 A;  1M35 A;  2MAT A;  2Q92 A;  3MR1 A;  4IDY A;  4B28 A;  4FLL A;  1QZY A;  4FO7 A;  1PV9 A;  1YW9 A;  1C27 A;  4S2T P;  2BHD A;  4U76 A;  2BHC A;  3ROR A;  2V3Y A;  3IU9 A;  4IF7 A;  5D6F A;  1C23 A;  4U6C A;  4S01 A;  1YW7 A;  1MAT A;  4R60 A;  4JUQ A;  1R5G A;  4IKT A;  4RGZ 1;  4Z7M A;  4U75 A;  5JFR A;  5D6E A;  2GGB A;  3D27 A;  4ZWU A;  3PKA A;  3RVA A;  2EVM A;  2BN7 A;  1JAW A;  1WL9 A;  1QXW A;  3IU8 A;  3PKB A;  4FKC A;  4U71 A;  1KQ9 A;  2EVO A;  2GG2 A;  2GZ5 A;  2GGC A;  2B3H A;  2NQ7 A;  2ZSG A;  4U1B A;  3MX6 A;  5CIK A;  1QXY A;  3PKC A;  1B6A A;  2P98 A;  4U70 A;  2B3K A;  2BWV A;  2ADU A;  4S2R P;  3IG4 A;  1XGO A;  1R58 A;  2GG3 A;  1WL6 A;  1YVM A;  2EA2 A;  1C21 A;  2B3L A;  4FLI A;  5CDL A;  1W2M A;  2BWY A;  1XNZ A;  2Q96 A;  2GG0 A;  4FUK A;  1C22 A;  1WN1 A;  2GA2 A;  2IW2 A;  4A6W A;  2V3X A;  4QR8 A;  4KM3 A;  1O0X A;  1WLR A;  5CLS A;  1A16 A;  1YJ3 A;  3L7G A;  4IEC A;  4IU6 A;  5CDV A;  4PNC A;  5JHU A;  3Q6D A;  4U6E A;  1KQ0 A;  1W7V A;  4IKS A;  4RZY A;  2GG8 A;  2P99 A;  4S00 A;  2Q94 A;  4EGE A;  2GU5 A;  3TAV A;  2G6P A;  3IU7 A;  3BIT A;  1N51 A;  1B59 A;  3CTZ A;  1QXZ A;  2BHA A;  2GG9 A;  4MAT A;  3BIQ A;  2BH3 A;  4IKR A;  4IKU A;  4OOK A;  1XGM A;  4IPA A;  1WKM A;  2GU7 A;  2HOW A;  5FCF A;  3PKE A;  2Q93 A;  2Q95 A;  3S6B A;  2BWS A;  2OAZ A;  4U6J A;  2BWU A;  2GU4 A;  5CNX A;  1R5H A;  4PV4 A;  4ZNG A; 
#chains in the Genus database with same CATH homology
 3CB6 A;  1YW8 A;  4ZWO A;  2BWX A;  1BOA A;  2Q8K A;  2BHB A;  2EA4 A;  4FO8 A;  3FMR A;  5CE6 A;  4U6W A;  2GU6 A;  3FM3 A;  2BWT A;  2P9A A;  1KP0 A;  1Y1N A;  3L24 A;  1WY2 A;  4HXX A;  5JI6 A;  4U69 A;  3BIP A;  3FMQ A;  1XGS A;  1WBQ A;  3PKD A;  4FLJ A;  1CHM A;  5FCH A;  4FLK A;  4ZWP A;  2BWW A;  5CDE A;  3CB5 A;  5E5B A;  4A6V A;  2GTX A;  1BN5 A;  4U6Z A;  1XGN A;  3MAT A;  2GG7 A;  2BB7 A;  2OKN A;  2EVC A;  4RZZ A;  2V3Z A;  4U73 A;  2DFI A;  2NQ6 A;  1C24 A;  2GG5 A;  2V6C A;  3TB5 A;  1M35 A;  2MAT A;  2Q92 A;  3MR1 A;  4IDY A;  4B28 A;  4FLL A;  1QZY A;  4FO7 A;  1PV9 A;  1YW9 A;  1C27 A;  4S2T P;  2BHD A;  4U76 A;  2BHC A;  3ROR A;  2V3Y A;  3IU9 A;  4IF7 A;  5D6F A;  1C23 A;  4U6C A;  4S01 A;  1YW7 A;  1MAT A;  4R60 A;  4JUQ A;  1R5G A;  4IKT A;  4RGZ 1;  4Z7M A;  4U75 A;  5JFR A;  5D6E A;  2GGB A;  3D27 A;  4ZWU A;  3PKA A;  3RVA A;  2EVM A;  2BN7 A;  1JAW A;  1WL9 A;  1QXW A;  3IU8 A;  3PKB A;  4FKC A;  4U71 A;  1KQ9 A;  2EVO A;  2GG2 A;  2GZ5 A;  2GGC A;  2B3H A;  2NQ7 A;  2ZSG A;  4U1B A;  3MX6 A;  5CIK A;  1QXY A;  3PKC A;  1B6A A;  2P98 A;  4U70 A;  2B3K A;  2BWV A;  2ADU A;  4S2R P;  3IG4 A;  1XGO A;  1R58 A;  2GG3 A;  1WL6 A;  1YVM A;  2EA2 A;  1C21 A;  2B3L A;  4FLI A;  5CDL A;  1W2M A;  2BWY A;  1XNZ A;  2Q96 A;  2GG0 A;  4FUK A;  1C22 A;  1WN1 A;  2GA2 A;  2IW2 A;  4A6W A;  2V3X A;  4QR8 A;  4KM3 A;  1O0X A;  1WLR A;  5CLS A;  1A16 A;  1YJ3 A;  3L7G A;  4IEC A;  4IU6 A;  5CDV A;  4PNC A;  5JHU A;  3Q6D A;  4U6E A;  1KQ0 A;  1W7V A;  4IKS A;  4RZY A;  2GG8 A;  2P99 A;  4S00 A;  2Q94 A;  4EGE A;  2GU5 A;  3TAV A;  2G6P A;  3IU7 A;  3BIT A;  1N51 A;  1B59 A;  3CTZ A;  1QXZ A;  2BHA A;  2GG9 A;  4MAT A;  3BIQ A;  2BH3 A;  4IKR A;  4IKU A;  4OOK A;  1XGM A;  4IPA A;  1WKM A;  2GU7 A;  2HOW A;  5FCF A;  3PKE A;  2Q93 A;  2Q95 A;  3S6B A;  2BWS A;  2OAZ A;  4U6J A;  2BWU A;  2GU4 A;  5CNX A;  1R5H A;  4PV4 A;  4ZNG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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