1MI1A

Crystal structure of the ph-beach domain of human neurobeachin
Total Genus 111
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
111
sequence length
414
structure length
414
Chain Sequence
b'GPVVLSTPAQLIAPVVVAKGTLSITTTEIYFEVDEDDSAFKKIDTKVLAYTEGLHGKWMFSEIRAVFSRRYLLQNTALEVFMANRTSVMFNFPDQATVKKVVYSLPRVGVGTSYGLPQARRISLATPRQLYKSSNMTQRWQRREISNFEYLMFLNTIAGRTYNDLNQYPVFPWVLTNYESEELDLTLPGNFRDLSKPIGALNPKRAVFYAERYETWEDDQSPPYHYNTHYSTATSTLSWLVRIEPFTTFFLNANDGKFDHPDRTFSSVARSWRTSQRDTSDVKELIPEFYYLPEMFVNSNGYNLGVREDEVVVNDVDLPPWAKKPEDFVRINRMALESEFVSCQLHQWIDLIFGYKQRGPEAVRALNVFHYLTYEGSVNLDSITDPVLREAMEAQIQNFGQTPSQLLIEPHPPR'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Neurobeachin
molecule tags Signaling protein
source organism Homo sapiens
publication title Crystal structure of the BEACH domain reveals an unusual fold and extensive association with a novel PH domain.
pubmed doi rcsb
total genus 111
structure length 414
sequence length 414
chains with identical sequence B
ec nomenclature
pdb deposition date 2002-08-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02138 Beach Beige/BEACH domain
A PF14844 PH_BEACH PH domain associated with Beige/BEACH
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1540.10 Mainly Alpha Orthogonal Bundle Neurobeachin; Chain: A, domain 1 BEACH domain 1mi1A02
2.30.29.40 Mainly Beta Roll PH-domain like PH domain-like; domain 1 1mi1A01
1MI1A 1T77A
chains in the Genus database with same CATH superfamily
5C6RA 3DXEA 2DYNA 4K81A 2EJ8A 2OQBA 5LONB 1SHCA 3D8FA 3SV1A 5JHGA 3CXBB 2DX5A 2LOXA 2KUQA 1MK7B 2EC1A 4EJNA 5JLJB 2PZ1A 5C5BA 1ZC4B 3TFMA 3A98B 1IRSA 2D10A 1V5PA 4KHAA 4CSQA 2NMBA 2I1JA 3ODXA 4IFSA 3MDBC 3QIJA 1W1GA 4Z2NA 2R09A 2Z0QA 5EFXA 2ELAA 3OANA 4IAPA 2KR0A 1FGYA 1PFJA 2KCJA 4KAXB 5JHHA 2Z0OA 3NW8A 4OSNA 2COAA 2D9VA 2Z13A 4KHBA 4YL8A 3ZDTA 1ZYIA 5D3YA 2D4QA 4D6WA 2X18A 3WA0A 2IFSA 3NSUA 3PVUA 2YVCA 1MK9B 1DYNA 1W1DA 2IYBA 1X1GA 4H8SA 1XD4A 3ULCA 4DIXA 2KIGA 3SO6A 1UNPA 2H7EA 1DDVA 2NBVA 1EF1A 2N0YA 2Z4DA 2I5FA 3TO1A 1E5WA 1U29A 5IRSA 2K2UA 3KZ1A 5C79A 1DROA 2DYQA 1K5GB 4HAWB 2COCA 4HATB 4WSFA 5DHAB 2I5CA 2LYDA 2DX1A 2OTXA 4K17A 5CLLB 1GG3A 2ELBA 4QJ4B 2ZKMX 2V76A 2GUMA 2MDXA 2Z0PA 1AWEA 1U2BA 3D8DA 3GYOA 3DCXA 3MPXA 1Q67A 1WJMA 4F7HA 2FJLA 3B77A 1MAIA 1KI1B 3KRWA 4YONA 2KGXB 5C5BB 1BWNA 2VKIA 2LG1A 1TJ6A 2EMTA 4TYZA 4DX8A 2DA0A 1FGZA 4Z2MB 1XX0A 3P7ZA 1Y19B 5D3VA 3SYXA 5HE0A 3M1IB 3FM8C 1WGUA 2P8VA 4MY6A 2GJYA 2DLWA 4HB2B 1WI1A 2R2YA 1U27A 1TQZA 2P0FA 1X86A 2CAYA 4EMOA 5L81A 2UZRA 2KUPA 1FHOA 2RSGA 2L2IA 3NWAA 4DBBA 3OHMB 4HDOA 5C16A 1UPQA 1MI1A 2R0DA 1Z87A 2DHJA 2LOZA 4GOUA 5JP4A 4HAVB 2YT0A 3ODOA 3QWMA 1FAOA 3P6AA 2NZ8B 1DBHA 1QC6A 1U5GA 2P0DA 4GPTB 1FOEA 4A5KA 5GOWB 4B6HA 3A8PA 1M7EA 2J59M 2DHKA 4NSWA 2D11A 2GCLA 3BJIA 3VOQA 2L1CA 3PVWA 3SNHA 4DXAB 1OY2A 2LKOA 2ZPYA 1EVHA 3T06A 4HB4B 2CODA 5KCVA 2RLOA 4F7UP 2G35A 4HHVA 3ZVRA 2YSZA 2RRFA 1MIXA 4ZRJA 2GCJA 2MKRA 5DI9B 4MT7A 2AL6A 4GMVA 1T77A 2Y8GA 5KQ4A 4KVGB 2Y8FA 4XWXA 1XR0B 1WJ1A 2J0MA 1FHXA 2QKMA 5J3YA 2DKQA 2YS3A 1U5FA 5FI0A 3HW2B 1V61A 1NI2A 3ODWA 4WVFB 4K2PA 1UEFA 2YRYA 3ULBA 1UNQA 4QXAB 2JP2A 4KHBB 4MK0A 1WVHA 2W2XC 1P5TA 1ISNA 3SUZA 1V5UA 5I2MA 2AEHA 1SGHA 3D8EA 3HSAA 3X23A 4A6HA 4HB0B 2YS5A 3ML4A 3TCAA 1W1HA 2P0HA 4A6KA 4EKUA 1V5MA 2Q13A 1XODA 1P3RA 3FSSA 1J0WA 2CY5A 1X11A 1MKEA 5DH9B 2MWNB 1RJ2A 3U12A 1ZC3B 5I2SA 2D9XA 2QKLA 1UNRA 4GXBA 2W2XD 4KHOA 2K00A 3UZTA 2DFKA 3AU5A 1P6SA 2EMSA 1WGQA 3HK0A 5FI1A 2MFQA 2ADZA 1Y5OA 4ZRKA 2J0JA 4D0NB 2FJUB 1PLSA 3GYPA 4HAYB 5J3QA 1ZVRA 1AQCA 3A58A 2D2QA 2XQNM 3TW1A 4CYEA 3V5WA 1WG7A 2VRWB 5M4YB 2RVBB 2LULA 1LW3A 4HDQA 5D3XA 1B55A 2H7DA 1BTNA 3BINA 2K2JA 4GNKB 1BTKA 1H4RA 5HE1A 5KQ1A 2N23A 1U5DA 4HAZB 1OMWA 3DXDA 2HTHB 3A8QA 4Y94A 4OT1A 5DHFB 1DDWA 2RUKB 4A6FA 2M38A 2RGNB 5HE3A 3FEHA 2DHIA 4CHMA 5DIFB 5J3TA 1MIZB 3O96A 1BAKA 1EAZA 2D9YA 2UZSA 3LJUX 3CIKA 2BCJA 4L1RA 5D3WA 4HSIA 4DX90 3AU4A 5HE2A 2YF0A 2Y7BA 3PG7A 4IOYX 2DKPA 3F5RA 1J19A 3WYFB 2CY4A 1U5EA 1X05A 1RRPB 3TVVA 3VIAA 2KIEA 3NWDA 1XCGA 2ROVA 2COFA 1ZM0A 1KZGA 3HIEA 2Z14A 3G9WA 4BBKA 2I1KA 1EGXA 2J0KA 1GC6A 4C0AA 1GC7A 1X1FA 3PZDA 1QQGA 1DDMA 4WJ7A 1TXDA 4F7GA 2W2WA 1H10A 5CLQB 4GMXB 3N7CA 1I7AA 1UPRA 3KY9A 5D27A 3RCPA 4HB3B 1I2HA 2VSZA 2E2XA 1FHWA 2K49A 3FVCA 1V89A 1N3HA 3PEGA 3U7DA 1NU2A 2UVMA 4TKNA 4HAUB 1LB1A 1PMSA 4GZUA 3KSYA 4ZRIA 2M14A 3PSCA 5LG4B 2YS1A 3F0WA 2K8EA 3AJ4A 1K5DB 4K2OA 4GN1A 5LOPB 3DXCA 1M7RA 4CHJA 4PNKA 1OQNA 2YT1A 3PP2A 1FB8A 1V88A 2D9WA 4L6EA 4NY0A 4A6FB 3U8ZA 4PQ0A 1NTVA 1XKEA 2D9ZA 3IVFA 2Z59A 4QJ3B 4QJ5B 2DTCA 2YT2A 3QBVB 2RNRB 3NWFA 1ZSQA 1NTYA 3HQCA 1MPHA 2DN6A 4HAXB 2ROZB 1KZ7A 2HE7A 3KRXA 2GS0A 2CRFA 4P7IA 3PVLA
chains in the Genus database with same CATH topology
1MI1A 1T77A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1MI1 A;  1T77 A; 
#chains in the Genus database with same CATH topology
 5C6R A;  3DXE A;  2DYN A;  4K81 A;  2EJ8 A;  2OQB A;  5LON B;  1SHC A;  3D8F A;  3SV1 A;  5JHG A;  3CXB B;  2DX5 A;  2LOX A;  2KUQ A;  1MK7 B;  2EC1 A;  4EJN A;  5JLJ B;  2PZ1 A;  5C5B A;  1ZC4 B;  3TFM A;  3A98 B;  1IRS A;  2D10 A;  1V5P A;  4KHA A;  4CSQ A;  2NMB A;  2I1J A;  3ODX A;  4IFS A;  3MDB C;  3QIJ A;  1W1G A;  4Z2N A;  2R09 A;  2Z0Q A;  5EFX A;  2ELA A;  3OAN A;  4IAP A;  2KR0 A;  1FGY A;  1PFJ A;  2KCJ A;  4KAX B;  5JHH A;  2Z0O A;  3NW8 A;  4OSN A;  2COA A;  2D9V A;  2Z13 A;  4KHB A;  4YL8 A;  3ZDT A;  1ZYI A;  5D3Y A;  2D4Q A;  4D6W A;  2X18 A;  3WA0 A;  2IFS A;  3NSU A;  3PVU A;  2YVC A;  1MK9 B;  1DYN A;  1W1D A;  2IYB A;  1X1G A;  4H8S A;  1XD4 A;  3ULC A;  4DIX A;  2KIG A;  3SO6 A;  1UNP A;  2H7E A;  1DDV A;  2NBV A;  1EF1 A;  2N0Y A;  2Z4D A;  2I5F A;  3TO1 A;  1E5W A;  1U29 A;  5IRS A;  2K2U A;  3KZ1 A;  5C79 A;  1DRO A;  2DYQ A;  1K5G B;  4HAW B;  2COC A;  4HAT B;  4WSF A;  5DHA B;  2I5C A;  2LYD A;  2DX1 A;  2OTX A;  4K17 A;  5CLL B;  1GG3 A;  2ELB A;  4QJ4 B;  2ZKM X;  2V76 A;  2GUM A;  2MDX A;  2Z0P A;  1AWE A;  1U2B A;  3D8D A;  3GYO A;  3DCX A;  3MPX A;  1Q67 A;  1WJM A;  4F7H A;  2FJL A;  3B77 A;  1MAI A;  1KI1 B;  3KRW A;  4YON A;  2KGX B;  5C5B B;  1BWN A;  2VKI A;  2LG1 A;  1TJ6 A;  2EMT A;  4TYZ A;  4DX8 A;  2DA0 A;  1FGZ A;  4Z2M B;  1XX0 A;  3P7Z A;  1Y19 B;  5D3V A;  3SYX A;  5HE0 A;  3M1I B;  3FM8 C;  1WGU A;  2P8V A;  4MY6 A;  2GJY A;  2DLW A;  4HB2 B;  1WI1 A;  2R2Y A;  1U27 A;  1TQZ A;  2P0F A;  1X86 A;  2CAY A;  4EMO A;  5L81 A;  2UZR A;  2KUP A;  1FHO A;  2RSG A;  2L2I A;  3NWA A;  4DBB A;  3OHM B;  4HDO A;  5C16 A;  1UPQ A;  1MI1 A;  2R0D A;  1Z87 A;  2DHJ A;  2LOZ A;  4GOU A;  5JP4 A;  4HAV B;  2YT0 A;  3ODO A;  3QWM A;  1FAO A;  3P6A A;  2NZ8 B;  1DBH A;  1QC6 A;  1U5G A;  2P0D A;  4GPT B;  1FOE A;  4A5K A;  5GOW B;  4B6H A;  3A8P A;  1M7E A;  2J59 M;  2DHK A;  4NSW A;  2D11 A;  2GCL A;  3BJI A;  3VOQ A;  2L1C A;  3PVW A;  3SNH A;  4DXA B;  1OY2 A;  2LKO A;  2ZPY A;  1EVH A;  3T06 A;  4HB4 B;  2COD A;  5KCV A;  2RLO A;  4F7U P;  2G35 A;  4HHV A;  3ZVR A;  2YSZ A;  2RRF A;  1MIX A;  4ZRJ A;  2GCJ A;  2MKR A;  5DI9 B;  4MT7 A;  2AL6 A;  4GMV A;  1T77 A;  2Y8G A;  5KQ4 A;  4KVG B;  2Y8F A;  4XWX A;  1XR0 B;  1WJ1 A;  2J0M A;  1FHX A;  2QKM A;  5J3Y A;  2DKQ A;  2YS3 A;  1U5F A;  5FI0 A;  3HW2 B;  1V61 A;  1NI2 A;  3ODW A;  4WVF B;  4K2P A;  1UEF A;  2YRY A;  3ULB A;  1UNQ A;  4QXA B;  2JP2 A;  4KHB B;  4MK0 A;  1WVH A;  2W2X C;  1P5T A;  1ISN A;  3SUZ A;  1V5U A;  5I2M A;  2AEH A;  1SGH A;  3D8E A;  3HSA A;  3X23 A;  4A6H A;  4HB0 B;  2YS5 A;  3ML4 A;  3TCA A;  1W1H A;  2P0H A;  4A6K A;  4EKU A;  1V5M A;  2Q13 A;  1XOD A;  1P3R A;  3FSS A;  1J0W A;  2CY5 A;  1X11 A;  1MKE A;  5DH9 B;  2MWN B;  1RJ2 A;  3U12 A;  1ZC3 B;  5I2S A;  2D9X A;  2QKL A;  1UNR A;  4GXB A;  2W2X D;  4KHO A;  2K00 A;  3UZT A;  2DFK A;  3AU5 A;  1P6S A;  2EMS A;  1WGQ A;  3HK0 A;  5FI1 A;  2MFQ A;  2ADZ A;  1Y5O A;  4ZRK A;  2J0J A;  4D0N B;  2FJU B;  1PLS A;  3GYP A;  4HAY B;  5J3Q A;  1ZVR A;  1AQC A;  3A58 A;  2D2Q A;  2XQN M;  3TW1 A;  4CYE A;  3V5W A;  1WG7 A;  2VRW B;  5M4Y B;  2RVB B;  2LUL A;  1LW3 A;  4HDQ A;  5D3X A;  1B55 A;  2H7D A;  1BTN A;  3BIN A;  2K2J A;  4GNK B;  1BTK A;  1H4R A;  5HE1 A;  5KQ1 A;  2N23 A;  1U5D A;  4HAZ B;  1OMW A;  3DXD A;  2HTH B;  3A8Q A;  4Y94 A;  4OT1 A;  5DHF B;  1DDW A;  2RUK B;  4A6F A;  2M38 A;  2RGN B;  5HE3 A;  3FEH A;  2DHI A;  4CHM A;  5DIF B;  5J3T A;  1MIZ B;  3O96 A;  1BAK A;  1EAZ A;  2D9Y A;  2UZS A;  3LJU X;  3CIK A;  2BCJ A;  4L1R A;  5D3W A;  4HSI A;  4DX9 0;  3AU4 A;  5HE2 A;  2YF0 A;  2Y7B A;  3PG7 A;  4IOY X;  2DKP A;  3F5R A;  1J19 A;  3WYF B;  2CY4 A;  1U5E A;  1X05 A;  1RRP B;  3TVV A;  3VIA A;  2KIE A;  3NWD A;  1XCG A;  2ROV A;  2COF A;  1ZM0 A;  1KZG A;  3HIE A;  2Z14 A;  3G9W A;  4BBK A;  2I1K A;  1EGX A;  2J0K A;  1GC6 A;  4C0A A;  1GC7 A;  1X1F A;  3PZD A;  1QQG A;  1DDM A;  4WJ7 A;  1TXD A;  4F7G A;  2W2W A;  1H10 A;  5CLQ B;  4GMX B;  3N7C A;  1I7A A;  1UPR A;  3KY9 A;  5D27 A;  3RCP A;  4HB3 B;  1I2H A;  2VSZ A;  2E2X A;  1FHW A;  2K49 A;  3FVC A;  1V89 A;  1N3H A;  3PEG A;  3U7D A;  1NU2 A;  2UVM A;  4TKN A;  4HAU B;  1LB1 A;  1PMS A;  4GZU A;  3KSY A;  4ZRI A;  2M14 A;  3PSC A;  5LG4 B;  2YS1 A;  3F0W A;  2K8E A;  3AJ4 A;  1K5D B;  4K2O A;  4GN1 A;  5LOP B;  3DXC A;  1M7R A;  4CHJ A;  4PNK A;  1OQN A;  2YT1 A;  3PP2 A;  1FB8 A;  1V88 A;  2D9W A;  4L6E A;  4NY0 A;  4A6F B;  3U8Z A;  4PQ0 A;  1NTV A;  1XKE A;  2D9Z A;  3IVF A;  2Z59 A;  4QJ3 B;  4QJ5 B;  2DTC A;  2YT2 A;  3QBV B;  2RNR B;  3NWF A;  1ZSQ A;  1NTY A;  3HQC A;  1MPH A;  2DN6 A;  4HAX B;  2ROZ B;  1KZ7 A;  2HE7 A;  3KRX A;  2GS0 A;  2CRF A;  4P7I A;  3PVL A; 
#chains in the Genus database with same CATH homology
 1MI1 A;  1T77 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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