1MI1A

Crystal structure of the ph-beach domain of human neurobeachin
Total Genus 111
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
111
sequence length
414
structure length
414
Chain Sequence
GPVVLSTPAQLIAPVVVAKGTLSITTTEIYFEVDEDDSAFKKIDTKVLAYTEGLHGKWMFSEIRAVFSRRYLLQNTALEVFMANRTSVMFNFPDQATVKKVVYSLPRVGVGTSYGLPQARRISLATPRQLYKSSNMTQRWQRREISNFEYLMFLNTIAGRTYNDLNQYPVFPWVLTNYESEELDLTLPGNFRDLSKPIGALNPKRAVFYAERYETWEDDQSPPYHYNTHYSTATSTLSWLVRIEPFTTFFLNANDGKFDHPDRTFSSVARSWRTSQRDTSDVKELIPEFYYLPEMFVNSNGYNLGVREDEVVVNDVDLPPWAKKPEDFVRINRMALESEFVSCQLHQWIDLIFGYKQRGPEAVRALNVFHYLTYEGSVNLDSITDPVLREAMEAQIQNFGQTPSQLLIEPHPPR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of the BEACH domain reveals an unusual fold and extensive association with a novel PH domain.
pubmed doi rcsb
molecule keywords Neurobeachin
molecule tags Signaling protein
source organism Homo sapiens
total genus 111
structure length 414
sequence length 414
chains with identical sequence B
ec nomenclature
pdb deposition date 2002-08-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02138 Beach Beige/BEACH domain
A PF14844 PH_BEACH PH domain associated with Beige/BEACH
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1540.10 Mainly Alpha Orthogonal Bundle Neurobeachin; Chain: A, domain 1 BEACH domain 1mi1A02
2.30.29.40 Mainly Beta Roll PH-domain like PH domain-like; domain 1 1mi1A01
1T77A 1MI1A
chains in the Genus database with same CATH superfamily
1I2HA 1UNRA 3TFMA 1MIXA 5D3YA 1DYNA 2D4QA 3U8ZA 2DN6A 5D3WA 2P0HA 4NSWA 1RJ2A 1XODA 2QKMA 2UZSA 1M7EA 1P5TA 5CLQB 4QXAB 1ISNA 3BJIA 4HSIA 2ROVA 3U7DA 1X86A 4KAXB 3SUZA 4K17A 5JLJB 2D9ZA 2ADZA 4PQ0A 1WI1A 4F7UP 1K5GB 1ZC4B 2YT1A 2RRFA 1FGYA 1M7RA 4H8SA 4DX8A 3OHMB 1KZ7A 2YT0A 3F5RA 5FI1A 1BWNA 2D10A 4GZUA 5DH9B 2YF0A 1I7AA 2W2WA 3AJ4A 4CHJA 2E2XA 2DKQA 5EFXA 3AU5A 1RRPB 2ZKMX 3U12A 1X11A 5D3XA 2JP2A 2BCJA 2I1KA 1EGXA 2H7EA 2MKRA 3SNHA 2H7DA 2R2YA 4HAUB 1Q67A 1H10A 2YS5A 3KY9A 2DX1A 5D27A 5J3QA 5L81A 3NSUA 1EVHA 2V76A 1U2BA 3AU4A 2DKPA 1U29A 2HE7A 1DROA 4Z2MB 1SHCA 3KRWA 3ZVRA 5JHHA 1Y5OA 5C5BA 1IRSA 2CY4A 1UPQA 1UEFA 5KCVA 4PNKA 2UVMA 4EKUA 2LULA 5JHGA 1UNPA 1WVHA 1J19A 2GCJA 4DXAB 1DDMA 1XKEA 3DXCA 1AQCA 3NWFA 4CSQA 1W1DA 3MPXA 3VOQA 3A8QA 2EMTA 1OQNA 2ROZB 1KI1B 4WJ7A 3GYOA 4NY0A 3PG7A 3P7ZA 1U5FA 1FAOA 1X1FA 2AL6A 3UZTA 4A6HA 2DTCA 2FJLA 3QWMA 1Y19B 2YS1A 5CLLB 4F7GA 2Q13A 2DHKA 3KRXA 2KUPA 3A98B 5J3TA 2DA0A 4HAZB 2OTXA 4OSNA 1DDVA 2CRFA 4KHOA 1LW3A 2Z14A 1E5WA 2Y7BA 2AEHA 2DYQA 1QQGA 3HIEA 2COCA 2K00A 1T77A 1FGZA 4EJNA 2MWNB 2GUMA 3TO1A 1NTYA 4HB3B 2Z0PA 2DYNA 1J0WA 3FEHA 1U5GA 2L1CA 3O96A 4HATB 3HK0A 2KUQA 1FHOA 4YL8A 3SO6A 4TKNA 2W2XD 3V5WA 1NTVA 3A58A 2MFQA 3T06A 2EJ8A 1WJMA 2ZPYA 1TXDA 5LG4B 2VSZA 2J59M 4Z2NA 1SGHA 3RCPA 5DIFB 4KHBB 2J0KA 1X1GA 1P3RA 1V5UA 3KSYA 1DBHA 3MDBC 1AWEA 2D2QA 4HDQA 4QJ3B 2KIEA 4A6FB 1Z87A 3ODOA 2KCJA 2YRYA 2Z0QA 4GMVA 2LOXA 4D6WA 5I2SA 4HDOA 3F0WA 3HQCA 2LKOA 2Z4DA 4HHVA 2R09A 1UPRA 1ZC3B 1U27A 2G35A 4ZRJA 3CIKA 4L6EA 2Y8FA 3DXDA 3PSCA 1WJ1A 2Z0OA 1OMWA 5I2MA 4QJ4B 3FM8C 2CAYA 2D9VA 1ZSQA 5IRSA 1EF1A 2D11A 1XCGA 4GPTB 4L1RA 1WGUA 1ZYIA 1FOEA 2LOZA 1MI1A 4Y94A 5HE0A 5DHFB 1NU2A 2DFKA 2I5CA 2UZRA 3M1IB 2J0JA 2Z13A 1MPHA 5HE3A 2GS0A 2K8EA 4ZRKA 3QIJA 1MAIA 2K49A 4CYEA 2COAA 2ELBA 1X05A 1NI2A 4K2OA 1PLSA 2Y8GA 1PFJA 2EC1A 1QC6A 3DXEA 2I1JA 1FHWA 1MIZB 4IOYX 4MT7A 2D9WA 5FI0A 3PEGA 4A6KA 5C79A 4HB4B 1XR0B 1WGQA 2K2JA 3FVCA 3CXBB 2VKIA 4KVGB 2MDXA 4HAYB 3WA0A 4XWXA 3TVVA 1V5PA 4GMXB 4QJ5B 2IFSA 2YSZA 3BINA 3QBVB 1TQZA 3TW1A 4DIXA 4F7HA 3KZ1A 2OQBA 2P8VA 1MK9B 4GXBA 1H4RA 2QKLA 2ELAA 4HB2B 1V88A 2GCLA 1V89A 1KZGA 2LG1A 3SYXA 1GC7A 1U5EA 1GG3A 2DX5A 3FSSA 4P7IA 2RUKB 1B55A 1MK7B 3WYFB 1UNQA 2RVBB 4ZRIA 4IAPA 5LOPB 2HTHB 3LJUX 1FHXA 2GJYA 2XQNM 3HW2B 2VRWB 4K2PA 3D8EA 2N23A 2DLWA 2KIGA 2KR0A 2P0DA 2PZ1A 3NW8A 2N0YA 3ULCA 5JP4A 2NMBA 4K81A 1FB8A 1V61A 2L2IA 4WSFA 4DBBA 1XD4A 2RGNB 3PVWA 2EMSA 3A8PA 1EAZA 2I5FA 2KGXB 4DX90 2IYBA 2K2UA 1V5MA 1P6SA 3HSAA 4YONA 3PVUA 2M14A 3ULBA 4TYZA 1BTKA 4KHBA 2Z59A 1BAKA 4B6HA 5C16A 1XX0A 4A6FA 5M4YB 5DHAB 2D9XA 1W1HA 5C5BB 5HE1A 4IFSA 2P0FA 4GN1A 1ZVRA 3D8DA 5KQ1A 5D3VA 2CY5A 4GOUA 2CODA 5HE2A 3SV1A 3PZDA 4OT1A 3G9WA 1BTNA 4HAXB 2FJUB 5C6RA 1MKEA 3NWAA 4WVFB 2NBVA 2RNRB 2D9YA 1TJ6A 1W1GA 3N7CA 2RSGA 4A5KA 1WG7A 1OY2A 3ODWA 3IVFA 2W2XC 3GYPA 3X23A 3NWDA 4KHAA 5LONB 3DCXA 3VIAA 2M38A 4D0NB 4BBKA 1ZM0A 1PMSA 3ODXA 3OANA 3PVLA 5KQ4A 1LB1A 3ZDTA 2NZ8B 3ML4A 4MY6A 2DHJA 2J0MA 2YS3A 3B77A 2YVCA 5GOWB 4GNKB 5J3YA 5DI9B 2COFA 4MK0A 2LYDA 2R0DA 2YT2A 4HB0B 3D8FA 3PP2A 2X18A 1N3HA 3TCAA 2RLOA 4CHMA 4HAVB 2DHIA 4HAWB 4C0AA 1DDWA 1U5DA 1K5DB 1GC6A 4EMOA 3P6AA
chains in the Genus database with same CATH topology
1T77A 1MI1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1T77 A;  1MI1 A; 
#chains in the Genus database with same CATH topology
 1I2H A;  1UNR A;  3TFM A;  1MIX A;  5D3Y A;  1DYN A;  2D4Q A;  3U8Z A;  2DN6 A;  5D3W A;  2P0H A;  4NSW A;  1RJ2 A;  1XOD A;  2QKM A;  2UZS A;  1M7E A;  1P5T A;  5CLQ B;  4QXA B;  1ISN A;  3BJI A;  4HSI A;  2ROV A;  3U7D A;  1X86 A;  4KAX B;  3SUZ A;  4K17 A;  5JLJ B;  2D9Z A;  2ADZ A;  4PQ0 A;  1WI1 A;  4F7U P;  1K5G B;  1ZC4 B;  2YT1 A;  2RRF A;  1FGY A;  1M7R A;  4H8S A;  4DX8 A;  3OHM B;  1KZ7 A;  2YT0 A;  3F5R A;  5FI1 A;  1BWN A;  2D10 A;  4GZU A;  5DH9 B;  2YF0 A;  1I7A A;  2W2W A;  3AJ4 A;  4CHJ A;  2E2X A;  2DKQ A;  5EFX A;  3AU5 A;  1RRP B;  2ZKM X;  3U12 A;  1X11 A;  5D3X A;  2JP2 A;  2BCJ A;  2I1K A;  1EGX A;  2H7E A;  2MKR A;  3SNH A;  2H7D A;  2R2Y A;  4HAU B;  1Q67 A;  1H10 A;  2YS5 A;  3KY9 A;  2DX1 A;  5D27 A;  5J3Q A;  5L81 A;  3NSU A;  1EVH A;  2V76 A;  1U2B A;  3AU4 A;  2DKP A;  1U29 A;  2HE7 A;  1DRO A;  4Z2M B;  1SHC A;  3KRW A;  3ZVR A;  5JHH A;  1Y5O A;  5C5B A;  1IRS A;  2CY4 A;  1UPQ A;  1UEF A;  5KCV A;  4PNK A;  2UVM A;  4EKU A;  2LUL A;  5JHG A;  1UNP A;  1WVH A;  1J19 A;  2GCJ A;  4DXA B;  1DDM A;  1XKE A;  3DXC A;  1AQC A;  3NWF A;  4CSQ A;  1W1D A;  3MPX A;  3VOQ A;  3A8Q A;  2EMT A;  1OQN A;  2ROZ B;  1KI1 B;  4WJ7 A;  3GYO A;  4NY0 A;  3PG7 A;  3P7Z A;  1U5F A;  1FAO A;  1X1F A;  2AL6 A;  3UZT A;  4A6H A;  2DTC A;  2FJL A;  3QWM A;  1Y19 B;  2YS1 A;  5CLL B;  4F7G A;  2Q13 A;  2DHK A;  3KRX A;  2KUP A;  3A98 B;  5J3T A;  2DA0 A;  4HAZ B;  2OTX A;  4OSN A;  1DDV A;  2CRF A;  4KHO A;  1LW3 A;  2Z14 A;  1E5W A;  2Y7B A;  2AEH A;  2DYQ A;  1QQG A;  3HIE A;  2COC A;  2K00 A;  1T77 A;  1FGZ A;  4EJN A;  2MWN B;  2GUM A;  3TO1 A;  1NTY A;  4HB3 B;  2Z0P A;  2DYN A;  1J0W A;  3FEH A;  1U5G A;  2L1C A;  3O96 A;  4HAT B;  3HK0 A;  2KUQ A;  1FHO A;  4YL8 A;  3SO6 A;  4TKN A;  2W2X D;  3V5W A;  1NTV A;  3A58 A;  2MFQ A;  3T06 A;  2EJ8 A;  1WJM A;  2ZPY A;  1TXD A;  5LG4 B;  2VSZ A;  2J59 M;  4Z2N A;  1SGH A;  3RCP A;  5DIF B;  4KHB B;  2J0K A;  1X1G A;  1P3R A;  1V5U A;  3KSY A;  1DBH A;  3MDB C;  1AWE A;  2D2Q A;  4HDQ A;  4QJ3 B;  2KIE A;  4A6F B;  1Z87 A;  3ODO A;  2KCJ A;  2YRY A;  2Z0Q A;  4GMV A;  2LOX A;  4D6W A;  5I2S A;  4HDO A;  3F0W A;  3HQC A;  2LKO A;  2Z4D A;  4HHV A;  2R09 A;  1UPR A;  1ZC3 B;  1U27 A;  2G35 A;  4ZRJ A;  3CIK A;  4L6E A;  2Y8F A;  3DXD A;  3PSC A;  1WJ1 A;  2Z0O A;  1OMW A;  5I2M A;  4QJ4 B;  3FM8 C;  2CAY A;  2D9V A;  1ZSQ A;  5IRS A;  1EF1 A;  2D11 A;  1XCG A;  4GPT B;  4L1R A;  1WGU A;  1ZYI A;  1FOE A;  2LOZ A;  1MI1 A;  4Y94 A;  5HE0 A;  5DHF B;  1NU2 A;  2DFK A;  2I5C A;  2UZR A;  3M1I B;  2J0J A;  2Z13 A;  1MPH A;  5HE3 A;  2GS0 A;  2K8E A;  4ZRK A;  3QIJ A;  1MAI A;  2K49 A;  4CYE A;  2COA A;  2ELB A;  1X05 A;  1NI2 A;  4K2O A;  1PLS A;  2Y8G A;  1PFJ A;  2EC1 A;  1QC6 A;  3DXE A;  2I1J A;  1FHW A;  1MIZ B;  4IOY X;  4MT7 A;  2D9W A;  5FI0 A;  3PEG A;  4A6K A;  5C79 A;  4HB4 B;  1XR0 B;  1WGQ A;  2K2J A;  3FVC A;  3CXB B;  2VKI A;  4KVG B;  2MDX A;  4HAY B;  3WA0 A;  4XWX A;  3TVV A;  1V5P A;  4GMX B;  4QJ5 B;  2IFS A;  2YSZ A;  3BIN A;  3QBV B;  1TQZ A;  3TW1 A;  4DIX A;  4F7H A;  3KZ1 A;  2OQB A;  2P8V A;  1MK9 B;  4GXB A;  1H4R A;  2QKL A;  2ELA A;  4HB2 B;  1V88 A;  2GCL A;  1V89 A;  1KZG A;  2LG1 A;  3SYX A;  1GC7 A;  1U5E A;  1GG3 A;  2DX5 A;  3FSS A;  4P7I A;  2RUK B;  1B55 A;  1MK7 B;  3WYF B;  1UNQ A;  2RVB B;  4ZRI A;  4IAP A;  5LOP B;  2HTH B;  3LJU X;  1FHX A;  2GJY A;  2XQN M;  3HW2 B;  2VRW B;  4K2P A;  3D8E A;  2N23 A;  2DLW A;  2KIG A;  2KR0 A;  2P0D A;  2PZ1 A;  3NW8 A;  2N0Y A;  3ULC A;  5JP4 A;  2NMB A;  4K81 A;  1FB8 A;  1V61 A;  2L2I A;  4WSF A;  4DBB A;  1XD4 A;  2RGN B;  3PVW A;  2EMS A;  3A8P A;  1EAZ A;  2I5F A;  2KGX B;  4DX9 0;  2IYB A;  2K2U A;  1V5M A;  1P6S A;  3HSA A;  4YON A;  3PVU A;  2M14 A;  3ULB A;  4TYZ A;  1BTK A;  4KHB A;  2Z59 A;  1BAK A;  4B6H A;  5C16 A;  1XX0 A;  4A6F A;  5M4Y B;  5DHA B;  2D9X A;  1W1H A;  5C5B B;  5HE1 A;  4IFS A;  2P0F A;  4GN1 A;  1ZVR A;  3D8D A;  5KQ1 A;  5D3V A;  2CY5 A;  4GOU A;  2COD A;  5HE2 A;  3SV1 A;  3PZD A;  4OT1 A;  3G9W A;  1BTN A;  4HAX B;  2FJU B;  5C6R A;  1MKE A;  3NWA A;  4WVF B;  2NBV A;  2RNR B;  2D9Y A;  1TJ6 A;  1W1G A;  3N7C A;  2RSG A;  4A5K A;  1WG7 A;  1OY2 A;  3ODW A;  3IVF A;  2W2X C;  3GYP A;  3X23 A;  3NWD A;  4KHA A;  5LON B;  3DCX A;  3VIA A;  2M38 A;  4D0N B;  4BBK A;  1ZM0 A;  1PMS A;  3ODX A;  3OAN A;  3PVL A;  5KQ4 A;  1LB1 A;  3ZDT A;  2NZ8 B;  3ML4 A;  4MY6 A;  2DHJ A;  2J0M A;  2YS3 A;  3B77 A;  2YVC A;  5GOW B;  4GNK B;  5J3Y A;  5DI9 B;  2COF A;  4MK0 A;  2LYD A;  2R0D A;  2YT2 A;  4HB0 B;  3D8F A;  3PP2 A;  2X18 A;  1N3H A;  3TCA A;  2RLO A;  4CHM A;  4HAV B;  2DHI A;  4HAW B;  4C0A A;  1DDW A;  1U5D A;  1K5D B;  1GC6 A;  4EMO A;  3P6A A; 
#chains in the Genus database with same CATH homology
 1T77 A;  1MI1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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