1MI1A

Crystal structure of the ph-beach domain of human neurobeachin
Total Genus 111
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
111
sequence length
414
structure length
414
Chain Sequence
GPVVLSTPAQLIAPVVVAKGTLSITTTEIYFEVDEDDSAFKKIDTKVLAYTEGLHGKWMFSEIRAVFSRRYLLQNTALEVFMANRTSVMFNFPDQATVKKVVYSLPRVGVGTSYGLPQARRISLATPRQLYKSSNMTQRWQRREISNFEYLMFLNTIAGRTYNDLNQYPVFPWVLTNYESEELDLTLPGNFRDLSKPIGALNPKRAVFYAERYETWEDDQSPPYHYNTHYSTATSTLSWLVRIEPFTTFFLNANDGKFDHPDRTFSSVARSWRTSQRDTSDVKELIPEFYYLPEMFVNSNGYNLGVREDEVVVNDVDLPPWAKKPEDFVRINRMALESEFVSCQLHQWIDLIFGYKQRGPEAVRALNVFHYLTYEGSVNLDSITDPVLREAMEAQIQNFGQTPSQLLIEPHPPR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Neurobeachin
publication title Crystal structure of the BEACH domain reveals an unusual fold and extensive association with a novel PH domain.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Signaling protein
total genus 111
structure length 414
sequence length 414
chains with identical sequence B
ec nomenclature
pdb deposition date 2002-08-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02138 Beach Beige/BEACH domain
A PF14844 PH_BEACH PH domain associated with Beige/BEACH
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1540.10 Mainly Alpha Orthogonal Bundle Neurobeachin; Chain: A, domain 1 BEACH domain 1mi1A02
2.30.29.40 Mainly Beta Roll PH-domain like PH domain-like; domain 1 1mi1A01
1T77A 1MI1A
chains in the Genus database with same CATH superfamily
5DH9B 1MKEA 1WG7A 1XR0B 2FJUB 2R09A 5C5BB 2MKRA 2UZRA 3F0WA 1GG3A 1K5GB 3SYXA 2LOXA 1WGQA 5I2MA 1UNQA 1ISNA 1DDWA 4GNKB 3SNHA 2J0MA 1NTYA 4F7HA 5KQ1A 2YF0A 3PZDA 4HB2B 4QJ3B 4NSWA 2DN6A 2YT2A 4OT1A 4L1RA 2P0DA 1FHXA 2RUKB 1XD4A 2Y7BA 1M7EA 2AL6A 5EFXA 2DKPA 3OHMB 4MK0A 1FHOA 3BINA 1PFJA 5LOPB 2CY5A 3ODWA 2ROZB 3MDBC 4WSFA 4IOYX 3SUZA 5C5BA 2Z4DA 4H8SA 4IAPA 4DBBA 3TCAA 2YT0A 2P0FA 2R2YA 2M14A 2K2UA 4MT7A 3PEGA 2G35A 4CSQA 1Y5OA 1LB1A 2KGXB 1FB8A 4EMOA 2KUQA 4KAXB 4L6EA 1Q67A 3V5WA 2J0JA 1XKEA 2D10A 3CXBB 3KRWA 1MAIA 1DROA 4HDOA 4A6KA 1U27A 2LKOA 1OY2A 2CY4A 1IRSA 2KCJA 2I5CA 4K2PA 3NWDA 1V61A 3NW8A 1I2HA 2I5FA 2NMBA 2Z0PA 4A6HA 2VRWB 4HAVB 1T77A 1X1FA 1P6SA 4HAYB 4DX8A 2V76A 2KIEA 2D9VA 3PVWA 2H7DA 4DXAB 4QXAB 3QIJA 1FHWA 1GC6A 4BBKA 4QJ4B 2L2IA 1N3HA 4QJ5B 1WGUA 1XODA 1SHCA 3GYOA 2Y8GA 3TVVA 2D9YA 2Z0QA 4CYEA 1XX0A 1OQNA 2YS3A 5IRSA 5DIFB 4DIXA 3U12A 4YONA 1ZC3B 2DYNA 3NWFA 3ULBA 1EAZA 3KRXA 1V5PA 3KZ1A 4GZUA 5J3QA 4CHJA 2J0KA 5D3XA 1J0WA 3O96A 1TXDA 3FSSA 5FI1A 4KHOA 1WJMA 2XQNM 3ML4A 2P8VA 3AJ4A 1W1GA 1Y19B 1FGYA 4TKNA 4KVGB 1I7AA 3GYPA 2GUMA 2ROVA 2CRFA 1U5DA 3ODXA 4P7IA 4B6HA 2IFSA 2W2XD 3A8PA 2ZKMX 1DYNA 1FAOA 4D6WA 4KHAA 4EKUA 1K5DB 1PLSA 5C79A 5D3YA 3TW1A 1QQGA 4HB3B 4TYZA 1RJ2A 5HE1A 5KCVA 2VSZA 2LOZA 3DXCA 5D3VA 2ADZA 4HHVA 2DHIA 3QWMA 4WVFB 2DFKA 5FI0A 2D2QA 1UPRA 3D8EA 2HE7A 5JHGA 2CODA 3FEHA 4D0NB 1U29A 1BTNA 5C16A 4EJNA 1AWEA 2IYBA 3ZVRA 2DX1A 4GPTB 3HQCA 2Z0OA 4HSIA 5JP4A 2EMSA 2ELBA 3VOQA 1X1GA 2D9ZA 2K2JA 1MIXA 1FOEA 3AU5A 1X05A 2QKLA 1UNRA 2Z13A 1NI2A 2DTCA 2AEHA 2MWNB 1H4RA 2DKQA 4PQ0A 2YVCA 2MDXA 4HB4B 4Y94A 4HAUB 3U7DA 1U5EA 2UZSA 3IVFA 1U5FA 3SV1A 1EF1A 1W1HA 3TFMA 4PNKA 2DYQA 3FVCA 4HAZB 1ZSQA 3RCPA 3WA0A 2EMTA 1MK9B 1ZVRA 4ZRJA 4GMXB 3SO6A 1SGHA 5LONB 2EJ8A 3WYFB 2DHJA 1V5MA 3A98B 3KY9A 2LULA 4MY6A 2J59M 5M4YB 4Z2MB 3P6AA 1GC7A 2D9WA 1NTVA 2RSGA 5CLLB 1ZM0A 1J19A 2L1CA 1ZC4B 5HE0A 5DHAB 4K17A 2KR0A 1KZ7A 1PMSA 1V5UA 1Z87A 5LG4B 2Z59A 3VIAA 2OTXA 1P5TA 3KSYA 1P3RA 2E2XA 5KQ4A 1UPQA 4WJ7A 4C0AA 5D3WA 4HATB 4GN1A 2H7EA 1TJ6A 5JHHA 2RRFA 3P7ZA 4ZRIA 1ZYIA 2D11A 1NU2A 2D9XA 2M38A 1RRPB 1KZGA 4XWXA 1FGZA 2KIGA 2W2WA 3U8ZA 3F5RA 2GS0A 1AQCA 1DBHA 1DDVA 4HB0B 3DXEA 4HDQA 1QC6A 2HTHB 1E5WA 1MK7B 1H10A 1OMWA 1MIZB 5I2SA 2YRYA 3DXDA 5DHFB 3PSCA 3OANA 2D4QA 2R0DA 2COAA 2COCA 2VKIA 1M7RA 3ODOA 3HIEA 1DDMA 3LJUX 2LG1A 2Z14A 3M1IB 2ELAA 1BAKA 3PG7A 1W1DA 1UEFA 3X23A 2DLWA 2YS1A 3CIKA 1XCGA 2GCLA 2GCJA 2RLOA 3BJIA 1KI1B 1X86A 2QKMA 3ULCA 4F7UP 4F7GA 1MPHA 2BCJA 1BTKA 4KHBB 2GJYA 2PZ1A 3A58A 3N7CA 5HE3A 5CLQB 2W2XC 3PP2A 1U2BA 2I1JA 4GOUA 5L81A 2COFA 2X18A 2DX5A 4HAWB 3DCXA 2DHKA 5DI9B 1EGXA 2YS5A 3HW2B 4IFSA 3D8FA 1LW3A 1UNPA 2K00A 2MFQA 2CAYA 5GOWB 2EC1A 2UVMA 4A6FB 4K81A 1BWNA 2LYDA 3MPXA 1EVHA 3D8DA 3UZTA 1WI1A 4YL8A 3TO1A 5J3TA 2RVBB 4KHBA 4Z2NA 5D27A 2DA0A 2N0YA 5J3YA 1X11A 2N23A 1MI1A 1WVHA 2K49A 4K2OA 4HAXB 5HE2A 2RNRB 5C6RA 4A5KA 2KUPA 2Q13A 4DX90 4GXBA 1WJ1A 2YT1A 3G9WA 3QBVB 5JLJB 3PVUA 2YSZA 2P0HA 3HSAA 4OSNA 3FM8C 3HK0A 2FJLA 4A6FA 1U5GA 1B55A 3PVLA 2OQBA 1V89A 2JP2A 2RGNB 4NY0A 2I1KA 4CHMA 3B77A 3NWAA 3T06A 4GMVA 4ZRKA 3ZDTA 2K8EA 3A8QA 3AU4A 1TQZA 2NZ8B 2Y8FA 2ZPYA 1V88A 3NSUA 2NBVA
chains in the Genus database with same CATH topology
1T77A 1MI1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1T77 A;  1MI1 A; 
#chains in the Genus database with same CATH topology
 5DH9 B;  1MKE A;  1WG7 A;  1XR0 B;  2FJU B;  2R09 A;  5C5B B;  2MKR A;  2UZR A;  3F0W A;  1GG3 A;  1K5G B;  3SYX A;  2LOX A;  1WGQ A;  5I2M A;  1UNQ A;  1ISN A;  1DDW A;  4GNK B;  3SNH A;  2J0M A;  1NTY A;  4F7H A;  5KQ1 A;  2YF0 A;  3PZD A;  4HB2 B;  4QJ3 B;  4NSW A;  2DN6 A;  2YT2 A;  4OT1 A;  4L1R A;  2P0D A;  1FHX A;  2RUK B;  1XD4 A;  2Y7B A;  1M7E A;  2AL6 A;  5EFX A;  2DKP A;  3OHM B;  4MK0 A;  1FHO A;  3BIN A;  1PFJ A;  5LOP B;  2CY5 A;  3ODW A;  2ROZ B;  3MDB C;  4WSF A;  4IOY X;  3SUZ A;  5C5B A;  2Z4D A;  4H8S A;  4IAP A;  4DBB A;  3TCA A;  2YT0 A;  2P0F A;  2R2Y A;  2M14 A;  2K2U A;  4MT7 A;  3PEG A;  2G35 A;  4CSQ A;  1Y5O A;  1LB1 A;  2KGX B;  1FB8 A;  4EMO A;  2KUQ A;  4KAX B;  4L6E A;  1Q67 A;  3V5W A;  2J0J A;  1XKE A;  2D10 A;  3CXB B;  3KRW A;  1MAI A;  1DRO A;  4HDO A;  4A6K A;  1U27 A;  2LKO A;  1OY2 A;  2CY4 A;  1IRS A;  2KCJ A;  2I5C A;  4K2P A;  3NWD A;  1V61 A;  3NW8 A;  1I2H A;  2I5F A;  2NMB A;  2Z0P A;  4A6H A;  2VRW B;  4HAV B;  1T77 A;  1X1F A;  1P6S A;  4HAY B;  4DX8 A;  2V76 A;  2KIE A;  2D9V A;  3PVW A;  2H7D A;  4DXA B;  4QXA B;  3QIJ A;  1FHW A;  1GC6 A;  4BBK A;  4QJ4 B;  2L2I A;  1N3H A;  4QJ5 B;  1WGU A;  1XOD A;  1SHC A;  3GYO A;  2Y8G A;  3TVV A;  2D9Y A;  2Z0Q A;  4CYE A;  1XX0 A;  1OQN A;  2YS3 A;  5IRS A;  5DIF B;  4DIX A;  3U12 A;  4YON A;  1ZC3 B;  2DYN A;  3NWF A;  3ULB A;  1EAZ A;  3KRX A;  1V5P A;  3KZ1 A;  4GZU A;  5J3Q A;  4CHJ A;  2J0K A;  5D3X A;  1J0W A;  3O96 A;  1TXD A;  3FSS A;  5FI1 A;  4KHO A;  1WJM A;  2XQN M;  3ML4 A;  2P8V A;  3AJ4 A;  1W1G A;  1Y19 B;  1FGY A;  4TKN A;  4KVG B;  1I7A A;  3GYP A;  2GUM A;  2ROV A;  2CRF A;  1U5D A;  3ODX A;  4P7I A;  4B6H A;  2IFS A;  2W2X D;  3A8P A;  2ZKM X;  1DYN A;  1FAO A;  4D6W A;  4KHA A;  4EKU A;  1K5D B;  1PLS A;  5C79 A;  5D3Y A;  3TW1 A;  1QQG A;  4HB3 B;  4TYZ A;  1RJ2 A;  5HE1 A;  5KCV A;  2VSZ A;  2LOZ A;  3DXC A;  5D3V A;  2ADZ A;  4HHV A;  2DHI A;  3QWM A;  4WVF B;  2DFK A;  5FI0 A;  2D2Q A;  1UPR A;  3D8E A;  2HE7 A;  5JHG A;  2COD A;  3FEH A;  4D0N B;  1U29 A;  1BTN A;  5C16 A;  4EJN A;  1AWE A;  2IYB A;  3ZVR A;  2DX1 A;  4GPT B;  3HQC A;  2Z0O A;  4HSI A;  5JP4 A;  2EMS A;  2ELB A;  3VOQ A;  1X1G A;  2D9Z A;  2K2J A;  1MIX A;  1FOE A;  3AU5 A;  1X05 A;  2QKL A;  1UNR A;  2Z13 A;  1NI2 A;  2DTC A;  2AEH A;  2MWN B;  1H4R A;  2DKQ A;  4PQ0 A;  2YVC A;  2MDX A;  4HB4 B;  4Y94 A;  4HAU B;  3U7D A;  1U5E A;  2UZS A;  3IVF A;  1U5F A;  3SV1 A;  1EF1 A;  1W1H A;  3TFM A;  4PNK A;  2DYQ A;  3FVC A;  4HAZ B;  1ZSQ A;  3RCP A;  3WA0 A;  2EMT A;  1MK9 B;  1ZVR A;  4ZRJ A;  4GMX B;  3SO6 A;  1SGH A;  5LON B;  2EJ8 A;  3WYF B;  2DHJ A;  1V5M A;  3A98 B;  3KY9 A;  2LUL A;  4MY6 A;  2J59 M;  5M4Y B;  4Z2M B;  3P6A A;  1GC7 A;  2D9W A;  1NTV A;  2RSG A;  5CLL B;  1ZM0 A;  1J19 A;  2L1C A;  1ZC4 B;  5HE0 A;  5DHA B;  4K17 A;  2KR0 A;  1KZ7 A;  1PMS A;  1V5U A;  1Z87 A;  5LG4 B;  2Z59 A;  3VIA A;  2OTX A;  1P5T A;  3KSY A;  1P3R A;  2E2X A;  5KQ4 A;  1UPQ A;  4WJ7 A;  4C0A A;  5D3W A;  4HAT B;  4GN1 A;  2H7E A;  1TJ6 A;  5JHH A;  2RRF A;  3P7Z A;  4ZRI A;  1ZYI A;  2D11 A;  1NU2 A;  2D9X A;  2M38 A;  1RRP B;  1KZG A;  4XWX A;  1FGZ A;  2KIG A;  2W2W A;  3U8Z A;  3F5R A;  2GS0 A;  1AQC A;  1DBH A;  1DDV A;  4HB0 B;  3DXE A;  4HDQ A;  1QC6 A;  2HTH B;  1E5W A;  1MK7 B;  1H10 A;  1OMW A;  1MIZ B;  5I2S A;  2YRY A;  3DXD A;  5DHF B;  3PSC A;  3OAN A;  2D4Q A;  2R0D A;  2COA A;  2COC A;  2VKI A;  1M7R A;  3ODO A;  3HIE A;  1DDM A;  3LJU X;  2LG1 A;  2Z14 A;  3M1I B;  2ELA A;  1BAK A;  3PG7 A;  1W1D A;  1UEF A;  3X23 A;  2DLW A;  2YS1 A;  3CIK A;  1XCG A;  2GCL A;  2GCJ A;  2RLO A;  3BJI A;  1KI1 B;  1X86 A;  2QKM A;  3ULC A;  4F7U P;  4F7G A;  1MPH A;  2BCJ A;  1BTK A;  4KHB B;  2GJY A;  2PZ1 A;  3A58 A;  3N7C A;  5HE3 A;  5CLQ B;  2W2X C;  3PP2 A;  1U2B A;  2I1J A;  4GOU A;  5L81 A;  2COF A;  2X18 A;  2DX5 A;  4HAW B;  3DCX A;  2DHK A;  5DI9 B;  1EGX A;  2YS5 A;  3HW2 B;  4IFS A;  3D8F A;  1LW3 A;  1UNP A;  2K00 A;  2MFQ A;  2CAY A;  5GOW B;  2EC1 A;  2UVM A;  4A6F B;  4K81 A;  1BWN A;  2LYD A;  3MPX A;  1EVH A;  3D8D A;  3UZT A;  1WI1 A;  4YL8 A;  3TO1 A;  5J3T A;  2RVB B;  4KHB A;  4Z2N A;  5D27 A;  2DA0 A;  2N0Y A;  5J3Y A;  1X11 A;  2N23 A;  1MI1 A;  1WVH A;  2K49 A;  4K2O A;  4HAX B;  5HE2 A;  2RNR B;  5C6R A;  4A5K A;  2KUP A;  2Q13 A;  4DX9 0;  4GXB A;  1WJ1 A;  2YT1 A;  3G9W A;  3QBV B;  5JLJ B;  3PVU A;  2YSZ A;  2P0H A;  3HSA A;  4OSN A;  3FM8 C;  3HK0 A;  2FJL A;  4A6F A;  1U5G A;  1B55 A;  3PVL A;  2OQB A;  1V89 A;  2JP2 A;  2RGN B;  4NY0 A;  2I1K A;  4CHM A;  3B77 A;  3NWA A;  3T06 A;  4GMV A;  4ZRK A;  3ZDT A;  2K8E A;  3A8Q A;  3AU4 A;  1TQZ A;  2NZ8 B;  2Y8F A;  2ZPY A;  1V88 A;  3NSU A;  2NBV A; 
#chains in the Genus database with same CATH homology
 1T77 A;  1MI1 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...