1MI1A

Crystal structure of the ph-beach domain of human neurobeachin
Total Genus 111
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
111
sequence length
414
structure length
414
Chain Sequence
GPVVLSTPAQLIAPVVVAKGTLSITTTEIYFEVDEDDSAFKKIDTKVLAYTEGLHGKWMFSEIRAVFSRRYLLQNTALEVFMANRTSVMFNFPDQATVKKVVYSLPRVGVGTSYGLPQARRISLATPRQLYKSSNMTQRWQRREISNFEYLMFLNTIAGRTYNDLNQYPVFPWVLTNYESEELDLTLPGNFRDLSKPIGALNPKRAVFYAERYETWEDDQSPPYHYNTHYSTATSTLSWLVRIEPFTTFFLNANDGKFDHPDRTFSSVARSWRTSQRDTSDVKELIPEFYYLPEMFVNSNGYNLGVREDEVVVNDVDLPPWAKKPEDFVRINRMALESEFVSCQLHQWIDLIFGYKQRGPEAVRALNVFHYLTYEGSVNLDSITDPVLREAMEAQIQNFGQTPSQLLIEPHPPR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of the BEACH domain reveals an unusual fold and extensive association with a novel PH domain.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Signaling protein
molecule keywords Neurobeachin
total genus 111
structure length 414
sequence length 414
chains with identical sequence B
ec nomenclature
pdb deposition date 2002-08-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02138 Beach Beige/BEACH domain
A PF14844 PH_BEACH PH domain associated with Beige/BEACH
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1540.10 Mainly Alpha Orthogonal Bundle Neurobeachin; Chain: A, domain 1 BEACH domain 1mi1A02
2.30.29.40 Mainly Beta Roll PH-domain like PH domain-like; domain 1 1mi1A01
1MI1A 1T77A
chains in the Genus database with same CATH superfamily
2CAYA 2MWNB 3SNHA 2M38A 1TQZA 4K17A 2DHJA 3PZDA 4K2OA 2L1CA 2ROZB 5J3QA 1N3HA 3TCAA 2NMBA 1U5GA 2YS3A 3QIJA 4WJ7A 2IFSA 3KY9A 3PEGA 4ZRKA 2D9YA 3PVWA 2LOZA 2J59M 3NWDA 2RUKB 4GZUA 3P6AA 4DX90 5J3TA 3ZVRA 5FI0A 3DXDA 2YT1A 4TKNA 2EC1A 1KZGA 1XCGA 4B6HA 4A6FA 1XODA 2GCLA 3B77A 4HB4B 3A98B 4HSIA 2FJUB 2JP2A 3PG7A 1U2BA 4OT1A 1FGZA 2Z14A 1U5FA 3AJ4A 1ZSQA 3A8QA 1KI1B 2L2IA 3U8ZA 1LW3A 4HAXB 5D27A 2X18A 2BCJA 2CRFA 3KRWA 2VKIA 1Z87A 4HDQA 1U29A 3GYPA 2I1JA 5GOWB 4CHJA 3TW1A 3OANA 4A5KA 1ISNA 4P7IA 1MK7B 1OY2A 5DI9B 2LULA 2J0MA 1MIXA 2OTXA 3BJIA 2KCJA 2W2XD 3DCXA 4KHAA 4KVGB 1T77A 1U5EA 4A6FB 3U7DA 2YT2A 2DHIA 1WI1A 5LONB 5DHFB 4HAVB 1FHOA 2RNRB 1EF1A 4YONA 4BBKA 2CY5A 2P0HA 2V76A 3G9WA 3KRXA 4TYZA 2DFKA 4QJ5B 3ULBA 4ZRIA 4HHVA 2E2XA 3LJUX 3O96A 2Y8FA 5DIFB 5C79A 2YSZA 3ODXA 1NTVA 5LOPB 4F7UP 4K2PA 3ML4A 2LKOA 1FGYA 2GS0A 3A58A 4PQ0A 1BWNA 3NWAA 3PVLA 5IRSA 1J0WA 3TVVA 3P7ZA 2K2JA 3T06A 2KUQA 2LG1A 2KUPA 1BAKA 1ZC3B 5HE3A 2DHKA 2YVCA 3D8EA 1X11A 5C6RA 2DLWA 2KIEA 2DA0A 5M4YB 1MPHA 1WJMA 4GXBA 3VOQA 1WGQA 4WVFB 5C5BB 5LG4B 2D4QA 1H4RA 1V5MA 1X05A 1UNPA 2ELBA 5JLJB 3HQCA 3SO6A 2Y7BA 3MPXA 1QC6A 2IYBA 1FAOA 1MAIA 4IOYX 5DH9B 3WYFB 3SYXA 1KZ7A 3DXCA 2D9ZA 2K8EA 5JHGA 4CHMA 1EVHA 1Y5OA 2D9XA 2N23A 2I5CA 1FHWA 2RLOA 3FM8C 3HIEA 5C16A 4HDOA 3V5WA 4PNKA 1WG7A 4KHBA 4DX8A 4HAUB 3DXEA 4HATB 4GNKB 2ELAA 4CYEA 2YS1A 1Q67A 2HE7A 3M1IB 4OSNA 2G35A 3WA0A 1NI2A 2D10A 4IAPA 3HW2B 4DIXA 3CXBB 1QQGA 1RJ2A 4MY6A 1V88A 3GYOA 5FI1A 2Z4DA 3N7CA 4MT7A 5KQ1A 4C0AA 2EMSA 5J3YA 3ODWA 2Z59A 4GOUA 4YL8A 1ZM0A 3A8PA 4KAXB 2Z0QA 2KGXB 1V61A 2ZKMX 1DROA 2YF0A 2GJYA 3TFMA 4EMOA 1E5WA 2GCJA 3FVCA 2GUMA 1V5PA 4GPTB 2QKLA 2ROVA 3MDBC 2RRFA 2UVMA 4GMXB 2R2YA 2K2UA 1P5TA 4Y94A 1NU2A 5D3WA 5D3YA 2Z0PA 4MK0A 1OQNA 1J19A 4H8SA 5C5BA 2AEHA 2LOXA 3CIKA 3NWFA 1MIZB 3ULCA 4QJ4B 3QBVB 1UPRA 4HAWB 1RRPB 4DBBA 1PFJA 2DN6A 2P0DA 3IVFA 4CSQA 1UEFA 3SUZA 1DBHA 2MKRA 2FJLA 1NTYA 2UZSA 1I7AA 5JP4A 1FB8A 2ADZA 4D0NB 3FSSA 1X86A 1Y19B 4DXAB 4NSWA 1OMWA 1WVHA 2HTHB 2CODA 2COFA 1P6SA 1XR0B 2P8VA 4NY0A 1MK9B 4HAYB 3VIAA 2DX1A 2K49A 5I2SA 5L81A 2H7EA 5HE0A 2D9VA 3ZDTA 2YT0A 4D6WA 1BTKA 2COAA 5CLLB 3NW8A 1M7EA 2I5FA 2DKQA 2CY4A 2NBVA 4HAZB 2J0KA 1SGHA 1XD4A 2D9WA 4F7HA 1UNRA 1M7RA 5D3VA 2R0DA 1FOEA 2RVBB 1U5DA 3F5RA 3F0WA 1UPQA 2YRYA 4KHBB 3AU4A 3HSAA 3OHMB 1DDVA 1ZC4B 1DYNA 2VRWB 2Y8GA 1XKEA 3ODOA 3D8DA 2W2XC 3PSCA 1W1HA 4A6HA 2W2WA 1X1FA 1ZYIA 2DKPA 1I2HA 3KSYA 4HB0B 3X23A 2NZ8B 3U12A 1GG3A 2UZRA 1AWEA 2D11A 2DX5A 2ZPYA 2YS5A 5DHAB 3TO1A 2RSGA 1K5GB 2OQBA 4ZRJA 1DDWA 2M14A 2DYNA 4L6EA 4HB3B 2EMTA 1EAZA 4KHOA 4EJNA 2PZ1A 3NSUA 1PLSA 1BTNA 1K5DB 2DTCA 1FHXA 5CLQB 1MKEA 2H7DA 2I1KA 1DDMA 3HK0A 4Z2NA 2LYDA 4A6KA 1ZVRA 2N0YA 4IFSA 1PMSA 2RGNB 3PP2A 1LB1A 2XQNM 4Z2MB 1TJ6A 1MI1A 1EGXA 3QWMA 3PVUA 1IRSA 1X1GA 2D2QA 1GC6A 1WGUA 2AL6A 2KIGA 4F7GA 2COCA 4HB2B 3BINA 1B55A 2P0FA 4K81A 1U27A 1WJ1A 2K00A 2J0JA 4L1RA 5KQ4A 4GMVA 4EKUA 2MFQA 4QJ3B 2Z0OA 1XX0A 2QKMA 1W1GA 3UZTA 1TXDA 3KZ1A 5EFXA 1AQCA 4GN1A 1W1DA 4QXAB 1SHCA 5KCVA 3RCPA 2KR0A 3FEHA 1V5UA 2DYQA 2Z13A 5HE2A 5HE1A 3AU5A 2R09A 2MDXA 2VSZA 2EJ8A 5D3XA 2Q13A 4WSFA 4XWXA 5I2MA 1H10A 1GC7A 1UNQA 1P3RA 3D8FA 1V89A 3SV1A 5JHHA
chains in the Genus database with same CATH topology
1MI1A 1T77A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1MI1 A;  1T77 A; 
#chains in the Genus database with same CATH topology
 2CAY A;  2MWN B;  3SNH A;  2M38 A;  1TQZ A;  4K17 A;  2DHJ A;  3PZD A;  4K2O A;  2L1C A;  2ROZ B;  5J3Q A;  1N3H A;  3TCA A;  2NMB A;  1U5G A;  2YS3 A;  3QIJ A;  4WJ7 A;  2IFS A;  3KY9 A;  3PEG A;  4ZRK A;  2D9Y A;  3PVW A;  2LOZ A;  2J59 M;  3NWD A;  2RUK B;  4GZU A;  3P6A A;  4DX9 0;  5J3T A;  3ZVR A;  5FI0 A;  3DXD A;  2YT1 A;  4TKN A;  2EC1 A;  1KZG A;  1XCG A;  4B6H A;  4A6F A;  1XOD A;  2GCL A;  3B77 A;  4HB4 B;  3A98 B;  4HSI A;  2FJU B;  2JP2 A;  3PG7 A;  1U2B A;  4OT1 A;  1FGZ A;  2Z14 A;  1U5F A;  3AJ4 A;  1ZSQ A;  3A8Q A;  1KI1 B;  2L2I A;  3U8Z A;  1LW3 A;  4HAX B;  5D27 A;  2X18 A;  2BCJ A;  2CRF A;  3KRW A;  2VKI A;  1Z87 A;  4HDQ A;  1U29 A;  3GYP A;  2I1J A;  5GOW B;  4CHJ A;  3TW1 A;  3OAN A;  4A5K A;  1ISN A;  4P7I A;  1MK7 B;  1OY2 A;  5DI9 B;  2LUL A;  2J0M A;  1MIX A;  2OTX A;  3BJI A;  2KCJ A;  2W2X D;  3DCX A;  4KHA A;  4KVG B;  1T77 A;  1U5E A;  4A6F B;  3U7D A;  2YT2 A;  2DHI A;  1WI1 A;  5LON B;  5DHF B;  4HAV B;  1FHO A;  2RNR B;  1EF1 A;  4YON A;  4BBK A;  2CY5 A;  2P0H A;  2V76 A;  3G9W A;  3KRX A;  4TYZ A;  2DFK A;  4QJ5 B;  3ULB A;  4ZRI A;  4HHV A;  2E2X A;  3LJU X;  3O96 A;  2Y8F A;  5DIF B;  5C79 A;  2YSZ A;  3ODX A;  1NTV A;  5LOP B;  4F7U P;  4K2P A;  3ML4 A;  2LKO A;  1FGY A;  2GS0 A;  3A58 A;  4PQ0 A;  1BWN A;  3NWA A;  3PVL A;  5IRS A;  1J0W A;  3TVV A;  3P7Z A;  2K2J A;  3T06 A;  2KUQ A;  2LG1 A;  2KUP A;  1BAK A;  1ZC3 B;  5HE3 A;  2DHK A;  2YVC A;  3D8E A;  1X11 A;  5C6R A;  2DLW A;  2KIE A;  2DA0 A;  5M4Y B;  1MPH A;  1WJM A;  4GXB A;  3VOQ A;  1WGQ A;  4WVF B;  5C5B B;  5LG4 B;  2D4Q A;  1H4R A;  1V5M A;  1X05 A;  1UNP A;  2ELB A;  5JLJ B;  3HQC A;  3SO6 A;  2Y7B A;  3MPX A;  1QC6 A;  2IYB A;  1FAO A;  1MAI A;  4IOY X;  5DH9 B;  3WYF B;  3SYX A;  1KZ7 A;  3DXC A;  2D9Z A;  2K8E A;  5JHG A;  4CHM A;  1EVH A;  1Y5O A;  2D9X A;  2N23 A;  2I5C A;  1FHW A;  2RLO A;  3FM8 C;  3HIE A;  5C16 A;  4HDO A;  3V5W A;  4PNK A;  1WG7 A;  4KHB A;  4DX8 A;  4HAU B;  3DXE A;  4HAT B;  4GNK B;  2ELA A;  4CYE A;  2YS1 A;  1Q67 A;  2HE7 A;  3M1I B;  4OSN A;  2G35 A;  3WA0 A;  1NI2 A;  2D10 A;  4IAP A;  3HW2 B;  4DIX A;  3CXB B;  1QQG A;  1RJ2 A;  4MY6 A;  1V88 A;  3GYO A;  5FI1 A;  2Z4D A;  3N7C A;  4MT7 A;  5KQ1 A;  4C0A A;  2EMS A;  5J3Y A;  3ODW A;  2Z59 A;  4GOU A;  4YL8 A;  1ZM0 A;  3A8P A;  4KAX B;  2Z0Q A;  2KGX B;  1V61 A;  2ZKM X;  1DRO A;  2YF0 A;  2GJY A;  3TFM A;  4EMO A;  1E5W A;  2GCJ A;  3FVC A;  2GUM A;  1V5P A;  4GPT B;  2QKL A;  2ROV A;  3MDB C;  2RRF A;  2UVM A;  4GMX B;  2R2Y A;  2K2U A;  1P5T A;  4Y94 A;  1NU2 A;  5D3W A;  5D3Y A;  2Z0P A;  4MK0 A;  1OQN A;  1J19 A;  4H8S A;  5C5B A;  2AEH A;  2LOX A;  3CIK A;  3NWF A;  1MIZ B;  3ULC A;  4QJ4 B;  3QBV B;  1UPR A;  4HAW B;  1RRP B;  4DBB A;  1PFJ A;  2DN6 A;  2P0D A;  3IVF A;  4CSQ A;  1UEF A;  3SUZ A;  1DBH A;  2MKR A;  2FJL A;  1NTY A;  2UZS A;  1I7A A;  5JP4 A;  1FB8 A;  2ADZ A;  4D0N B;  3FSS A;  1X86 A;  1Y19 B;  4DXA B;  4NSW A;  1OMW A;  1WVH A;  2HTH B;  2COD A;  2COF A;  1P6S A;  1XR0 B;  2P8V A;  4NY0 A;  1MK9 B;  4HAY B;  3VIA A;  2DX1 A;  2K49 A;  5I2S A;  5L81 A;  2H7E A;  5HE0 A;  2D9V A;  3ZDT A;  2YT0 A;  4D6W A;  1BTK A;  2COA A;  5CLL B;  3NW8 A;  1M7E A;  2I5F A;  2DKQ A;  2CY4 A;  2NBV A;  4HAZ B;  2J0K A;  1SGH A;  1XD4 A;  2D9W A;  4F7H A;  1UNR A;  1M7R A;  5D3V A;  2R0D A;  1FOE A;  2RVB B;  1U5D A;  3F5R A;  3F0W A;  1UPQ A;  2YRY A;  4KHB B;  3AU4 A;  3HSA A;  3OHM B;  1DDV A;  1ZC4 B;  1DYN A;  2VRW B;  2Y8G A;  1XKE A;  3ODO A;  3D8D A;  2W2X C;  3PSC A;  1W1H A;  4A6H A;  2W2W A;  1X1F A;  1ZYI A;  2DKP A;  1I2H A;  3KSY A;  4HB0 B;  3X23 A;  2NZ8 B;  3U12 A;  1GG3 A;  2UZR A;  1AWE A;  2D11 A;  2DX5 A;  2ZPY A;  2YS5 A;  5DHA B;  3TO1 A;  2RSG A;  1K5G B;  2OQB A;  4ZRJ A;  1DDW A;  2M14 A;  2DYN A;  4L6E A;  4HB3 B;  2EMT A;  1EAZ A;  4KHO A;  4EJN A;  2PZ1 A;  3NSU A;  1PLS A;  1BTN A;  1K5D B;  2DTC A;  1FHX A;  5CLQ B;  1MKE A;  2H7D A;  2I1K A;  1DDM A;  3HK0 A;  4Z2N A;  2LYD A;  4A6K A;  1ZVR A;  2N0Y A;  4IFS A;  1PMS A;  2RGN B;  3PP2 A;  1LB1 A;  2XQN M;  4Z2M B;  1TJ6 A;  1MI1 A;  1EGX A;  3QWM A;  3PVU A;  1IRS A;  1X1G A;  2D2Q A;  1GC6 A;  1WGU A;  2AL6 A;  2KIG A;  4F7G A;  2COC A;  4HB2 B;  3BIN A;  1B55 A;  2P0F A;  4K81 A;  1U27 A;  1WJ1 A;  2K00 A;  2J0J A;  4L1R A;  5KQ4 A;  4GMV A;  4EKU A;  2MFQ A;  4QJ3 B;  2Z0O A;  1XX0 A;  2QKM A;  1W1G A;  3UZT A;  1TXD A;  3KZ1 A;  5EFX A;  1AQC A;  4GN1 A;  1W1D A;  4QXA B;  1SHC A;  5KCV A;  3RCP A;  2KR0 A;  3FEH A;  1V5U A;  2DYQ A;  2Z13 A;  5HE2 A;  5HE1 A;  3AU5 A;  2R09 A;  2MDX A;  2VSZ A;  2EJ8 A;  5D3X A;  2Q13 A;  4WSF A;  4XWX A;  5I2M A;  1H10 A;  1GC7 A;  1UNQ A;  1P3R A;  3D8F A;  1V89 A;  3SV1 A;  5JHH A; 
#chains in the Genus database with same CATH homology
 1MI1 A;  1T77 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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