1MUNA

Catalytic domain of muty from escherichia coli d138n mutant
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
225
structure length
225
Chain Sequence
MQASQFSAQVLDWYDKYGRKTLPWQIDKTPYKVWLSEVMLQQTQVATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGGKFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILNGNVKRVLARCYAVSGWPGKKEVENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSKPKCSLCPLQNGCIAAANNSWALYPGKKPK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords ADENINE GLYCOSYLASE
publication title MutY catalytic core, mutant and bound adenine structures define specificity for DNA repair enzyme superfamily.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Dna repair
total genus 74
structure length 225
sequence length 225
ec nomenclature ec 3.2.2.31: Adenine glycosylase.
pdb deposition date 1998-08-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00633 HHH Helix-hairpin-helix motif
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
A PF10576 EndIII_4Fe-2S Iron-sulfur binding domain of endonuclease III
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1munA02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1munA01
1KG4A 4UNFA 4EJZA 1KG7A 2OFIA 1N3CA 2JG6A 4OFHA 3CW7A 1RRSA 1KO9A 4YPHA 3IHOA 4EA5A 3CVSA 1KG6A 4UOBA 3KNTA 3IH7A 2ABKA 1DIZA 2XHIA 1N39A 3KTUA 4B21A 4EW4A 1KG3A 1KEAA 1RRQA 1LMZA 4HSBA 3N5NX 2JHJA 3F0ZA 4YOQA 4E9EA 4EVVA 1XQOA 1N3AA 1PU8A 1WEFA 1MUNA 1PU7A 1WEGA 1KQJA 5AN4A 2YG8A 4EJYA 5DPKA 2NOHA 2YG9A 4DK9A 1M3QA 1LWVA 1MUDA 2JHNA 3OH6A 4E9FA 5CHZA 1M3HA 1LWYA 1KG2A 1YQRA 1PVSA 4AI5A 3G0QA 4B23A 1MUYA 5KN9A 3FHGA 1WEIA 2NOBA 1LWWA 3D4VA 3CWAA 1FN7A 1HU0A 4EW0A 1YQKA 1XG7A 1P59A 4E9HA 2NOFA 2NOEA 1ORPA 1PU6A 1MPGA 3I0XA 3S6IA 4YPRA 3CVTA 4OFEA 1ORNA 3FSPA 1NKUA 3I0WA 1VRLA 1YQLA 4B24A 4OFAA 5KN8A 3CWTA 4EA4A 1NGNA 1P7MA 4E9GA 3FHFA 3CWSA 3CWUA 1EBMA 2I5WA 4B22A 4PIIA 1YQMA 4AIAA 3OGDA 1KG5A 2H56A 2NOZA 4AI4A 2NOLA 3F10A 2NOIA 1XQPA 2OFKA 3N0UA 3OH9A
chains in the Genus database with same CATH superfamily
1KG4A 4UNFA 3L2RA 3S3OA 4EJZA 3L2VA 1KG7A 5FRMA 2OFIA 3S3MA 1N3CA 2JG6A 4OFHA 4ZTFA 3CW7A 1RRSA 1KO9A 4YPHA 3IHOA 3OYLA 4EA5A 3CVSA 1KG6A 4UOBA 2W03A 4E7HA 3KNTA 4E7IA 3R2XC 3NNQA 3IH7A 2ABKA 1DIZA 4BDYA 2XHIA 4BE2A 1N39A 3KTUA 4B21A 4EW4A 1KG3A 1KEAA 1RRQA 1LMZA 4HSBA 3N5NX 4NZGA 4ZTJA 2JHJA 3F0ZA 4YOQA 4IKFA 3L2QA 4E9EA 4EVVA 1XQOA 1N3AA 1PU8A 1WEFA 1MUNA 1PU7A 3OYIA 1WEGA 3OYAA 1KQJA 2JPSA 5AN4A 2YG8A 3OYJA 4EJYA 5DPKA 2NOHA 4E7LA 2YG9A 4DK9A 4BE0A 1M3QA 1LWVA 1MUDA 2JHNA 3OH6A 4E9FA 5CHZA 1M3HA 1LWYA 1KG2A 1YQRA 1PVSA 4AI5A 3G0QA 4B23A 1MUYA 5KN9A 3OYHA 4E7JA 3FHGA 1WEIA 3OYDA 2NOBA 1LWWA 3D4VA 3CWAA 1FN7A 3OYKA 5FROA 4EW0A 1HU0A 3OYNA 1XG7A 3OYEA 4E9HA 1YQKA 1P59A 2NOFA 2NOEA 2V75A 1ORPA 1PU6A 1MPGA 3I0XA 3S6IA 3OYCA 4YPRA 4BACA 3L2WA 3CVTA 4OFEA 1ORNA 3FSPA 5FRNA 1NKUA 3LCNA 3OS2A 3I0WA 3S3NA 1VRLA 3OYBA 1YQLA 3OYFA 3OYGA 3OS1A 4OFAA 4B24A 4E7KA 3VW4A 5KN8A 4BE1A 3CWTA 4EA4A 1NGNA 1P7MA 4E9GA 3FHFA 4BDZA 3CWSA 3CWUA 1EBMA 2I5WA 4B22A 4PIIA 3OYMA 3OS0A 3L2UA 1YQMA 4AIAA 3OGDA 1KG5A 2H56A 2NOZA 4AI4A 2NOLA 3F10A 1U84A 2W04A 2NOIA 1XQPA 2OFKA 3N0UA 3OY9A 3OH9A
chains in the Genus database with same CATH topology
1KG4A 4UNFA 4EJZA 1KG7A 2OFIA 1N3CA 2JG6A 4OFHA 3CW7A 1RRSA 1KO9A 4YPHA 3IHOA 4EA5A 3CVSA 1KG6A 4UOBA 3KNTA 3IH7A 2ABKA 1DIZA 2XHIA 1N39A 3KTUA 4B21A 4EW4A 1KG3A 1KEAA 1RRQA 1LMZA 4HSBA 3N5NX 2JHJA 3F0ZA 4YOQA 4E9EA 4EVVA 1XQOA 1N3AA 1PU8A 1WEFA 1MUNA 1PU7A 1WEGA 1KQJA 5AN4A 2YG8A 4EJYA 5DPKA 2NOHA 2YG9A 4DK9A 1M3QA 1LWVA 1MUDA 2JHNA 3OH6A 4E9FA 5CHZA 1M3HA 1LWYA 1KG2A 1YQRA 1PVSA 4AI5A 3G0QA 4B23A 1MUYA 5KN9A 3FHGA 1WEIA 2NOBA 1LWWA 3D4VA 3CWAA 1FN7A 1HU0A 4EW0A 1YQKA 1XG7A 1P59A 4E9HA 2NOFA 2NOEA 1ORPA 1PU6A 1MPGA 3I0XA 3S6IA 4YPRA 3CVTA 4OFEA 1ORNA 3FSPA 1NKUA 3I0WA 1VRLA 1YQLA 4B24A 4OFAA 5KN8A 3CWTA 4EA4A 1NGNA 1P7MA 4E9GA 3FHFA 3CWSA 3CWUA 1EBMA 2I5WA 4B22A 4PIIA 1YQMA 4AIAA 3OGDA 1KG5A 2H56A 2NOZA 4AI4A 2NOLA 3F10A 2NOIA 1XQPA 2OFKA 3N0UA 3OH9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KG4 A;  4UNF A;  4EJZ A;  1KG7 A;  2OFI A;  1N3C A;  2JG6 A;  4OFH A;  3CW7 A;  1RRS A;  1KO9 A;  4YPH A;  3IHO A;  4EA5 A;  3CVS A;  1KG6 A;  4UOB A;  3KNT A;  3IH7 A;  2ABK A;  1DIZ A;  2XHI A;  1N39 A;  3KTU A;  4B21 A;  4EW4 A;  1KG3 A;  1KEA A;  1RRQ A;  1LMZ A;  4HSB A;  3N5N X;  2JHJ A;  3F0Z A;  4YOQ A;  4E9E A;  4EVV A;  1XQO A;  1N3A A;  1PU8 A;  1WEF A;  1MUN A;  1PU7 A;  1WEG A;  1KQJ A;  5AN4 A;  2YG8 A;  4EJY A;  5DPK A;  2NOH A;  2YG9 A;  4DK9 A;  1M3Q A;  1LWV A;  1MUD A;  2JHN A;  3OH6 A;  4E9F A;  5CHZ A;  1M3H A;  1LWY A;  1KG2 A;  1YQR A;  1PVS A;  4AI5 A;  3G0Q A;  4B23 A;  1MUY A;  5KN9 A;  3FHG A;  1WEI A;  2NOB A;  1LWW A;  3D4V A;  3CWA A;  1FN7 A;  1HU0 A;  4EW0 A;  1YQK A;  1XG7 A;  1P59 A;  4E9H A;  2NOF A;  2NOE A;  1ORP A;  1PU6 A;  1MPG A;  3I0X A;  3S6I A;  4YPR A;  3CVT A;  4OFE A;  1ORN A;  3FSP A;  1NKU A;  3I0W A;  1VRL A;  1YQL A;  4B24 A;  4OFA A;  5KN8 A;  3CWT A;  4EA4 A;  1NGN A;  1P7M A;  4E9G A;  3FHF A;  3CWS A;  3CWU A;  1EBM A;  2I5W A;  4B22 A;  4PII A;  1YQM A;  4AIA A;  3OGD A;  1KG5 A;  2H56 A;  2NOZ A;  4AI4 A;  2NOL A;  3F10 A;  2NOI A;  1XQP A;  2OFK A;  3N0U A;  3OH9 A; 
#chains in the Genus database with same CATH topology
 1KG4 A;  4UNF A;  3L2R A;  3S3O A;  4EJZ A;  3L2V A;  1KG7 A;  5FRM A;  2OFI A;  3S3M A;  1N3C A;  2JG6 A;  4OFH A;  4ZTF A;  3CW7 A;  1RRS A;  1KO9 A;  4YPH A;  3IHO A;  3OYL A;  4EA5 A;  3CVS A;  1KG6 A;  4UOB A;  2W03 A;  4E7H A;  3KNT A;  4E7I A;  3R2X C;  3NNQ A;  3IH7 A;  2ABK A;  1DIZ A;  4BDY A;  2XHI A;  4BE2 A;  1N39 A;  3KTU A;  4B21 A;  4EW4 A;  1KG3 A;  1KEA A;  1RRQ A;  1LMZ A;  4HSB A;  3N5N X;  4NZG A;  4ZTJ A;  2JHJ A;  3F0Z A;  4YOQ A;  4IKF A;  3L2Q A;  4E9E A;  4EVV A;  1XQO A;  1N3A A;  1PU8 A;  1WEF A;  1MUN A;  1PU7 A;  3OYI A;  1WEG A;  3OYA A;  1KQJ A;  2JPS A;  5AN4 A;  2YG8 A;  3OYJ A;  4EJY A;  5DPK A;  2NOH A;  4E7L A;  2YG9 A;  4DK9 A;  4BE0 A;  1M3Q A;  1LWV A;  1MUD A;  2JHN A;  3OH6 A;  4E9F A;  5CHZ A;  1M3H A;  1LWY A;  1KG2 A;  1YQR A;  1PVS A;  4AI5 A;  3G0Q A;  4B23 A;  1MUY A;  5KN9 A;  3OYH A;  4E7J A;  3FHG A;  1WEI A;  3OYD A;  2NOB A;  1LWW A;  3D4V A;  3CWA A;  1FN7 A;  3OYK A;  5FRO A;  4EW0 A;  1HU0 A;  3OYN A;  1XG7 A;  3OYE A;  4E9H A;  1YQK A;  1P59 A;  2NOF A;  2NOE A;  2V75 A;  1ORP A;  1PU6 A;  1MPG A;  3I0X A;  3S6I A;  3OYC A;  4YPR A;  4BAC A;  3L2W A;  3CVT A;  4OFE A;  1ORN A;  3FSP A;  5FRN A;  1NKU A;  3LCN A;  3OS2 A;  3I0W A;  3S3N A;  1VRL A;  3OYB A;  1YQL A;  3OYF A;  3OYG A;  3OS1 A;  4OFA A;  4B24 A;  4E7K A;  3VW4 A;  5KN8 A;  4BE1 A;  3CWT A;  4EA4 A;  1NGN A;  1P7M A;  4E9G A;  3FHF A;  4BDZ A;  3CWS A;  3CWU A;  1EBM A;  2I5W A;  4B22 A;  4PII A;  3OYM A;  3OS0 A;  3L2U A;  1YQM A;  4AIA A;  3OGD A;  1KG5 A;  2H56 A;  2NOZ A;  4AI4 A;  2NOL A;  3F10 A;  1U84 A;  2W04 A;  2NOI A;  1XQP A;  2OFK A;  3N0U A;  3OY9 A;  3OH9 A; 
#chains in the Genus database with same CATH homology
 1KG4 A;  4UNF A;  4EJZ A;  1KG7 A;  2OFI A;  1N3C A;  2JG6 A;  4OFH A;  3CW7 A;  1RRS A;  1KO9 A;  4YPH A;  3IHO A;  4EA5 A;  3CVS A;  1KG6 A;  4UOB A;  3KNT A;  3IH7 A;  2ABK A;  1DIZ A;  2XHI A;  1N39 A;  3KTU A;  4B21 A;  4EW4 A;  1KG3 A;  1KEA A;  1RRQ A;  1LMZ A;  4HSB A;  3N5N X;  2JHJ A;  3F0Z A;  4YOQ A;  4E9E A;  4EVV A;  1XQO A;  1N3A A;  1PU8 A;  1WEF A;  1MUN A;  1PU7 A;  1WEG A;  1KQJ A;  5AN4 A;  2YG8 A;  4EJY A;  5DPK A;  2NOH A;  2YG9 A;  4DK9 A;  1M3Q A;  1LWV A;  1MUD A;  2JHN A;  3OH6 A;  4E9F A;  5CHZ A;  1M3H A;  1LWY A;  1KG2 A;  1YQR A;  1PVS A;  4AI5 A;  3G0Q A;  4B23 A;  1MUY A;  5KN9 A;  3FHG A;  1WEI A;  2NOB A;  1LWW A;  3D4V A;  3CWA A;  1FN7 A;  1HU0 A;  4EW0 A;  1YQK A;  1XG7 A;  1P59 A;  4E9H A;  2NOF A;  2NOE A;  1ORP A;  1PU6 A;  1MPG A;  3I0X A;  3S6I A;  4YPR A;  3CVT A;  4OFE A;  1ORN A;  3FSP A;  1NKU A;  3I0W A;  1VRL A;  1YQL A;  4B24 A;  4OFA A;  5KN8 A;  3CWT A;  4EA4 A;  1NGN A;  1P7M A;  4E9G A;  3FHF A;  3CWS A;  3CWU A;  1EBM A;  2I5W A;  4B22 A;  4PII A;  1YQM A;  4AIA A;  3OGD A;  1KG5 A;  2H56 A;  2NOZ A;  4AI4 A;  2NOL A;  3F10 A;  2NOI A;  1XQP A;  2OFK A;  3N0U A;  3OH9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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