1MVHA

Structure of the set domain histone lysine methyltransferase clr4
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
269
structure length
269
Chain Sequence
KLDSYTHLSFYEKRELFRKKLREIEGPEVTLVNEVDDEPCPSLDFQFISQYRLTQGVIPPDPNFQSGCNCSSLGGCDLNNPSRCECLDDLDEPTHFAYDAQGRVRADTGAVIYECNSFCSCSMECPNRVVQRGRTLPLEIFKTKEKGWGVRSLRFAPAGTFITCYLGEVITSAEAAKRDKNYDDDGITYLFDLDMFDDASEYTVDAQNYGDVSRFFNHSCSPNIAIYSAVRNHGFRTIYDLAFFAIKDIQPLEELTFDYAGAKDFSPVQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the SET domain histone lysine methyltransferase Clr4.
pubmed rcsb
molecule tags Transferase
source organism Schizosaccharomyces pombe
molecule keywords Cryptic loci regulator 4
total genus 60
structure length 269
sequence length 269
ec nomenclature ec 2.1.1.43: Histone-lysine N-methyltransferase.
pdb deposition date 2002-09-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00856 SET SET domain
A PF05033 Pre-SET Pre-SET motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.270.10 Mainly Beta Beta Complex Beta-clip-like SET domain 1mvhA00
3QWWA 1MVHA 1MVXA 3CBOA 5JIYA 2O8JA 3S8PA 3F9WA 1XQHA 4E47A 1ML9A 1N6AA 3QWPA 3OXLA 5TTFA 5KJNA 4RZ0A 5T5GA 2QPWA 5HI7A 3F9ZA 3M58A 5F5EA 4J8OA 4IJ8A 3MEKA 3TG4A 5EX0A 3IHXA 5ARGA 3S7FA 5EG2A 3SWCA 4YPUA 3RU0A 3CBMA 3PDNA 5LSZA 4YNDA 5JJ0A 5TH7A 3SW9A 3FPDA 4YNMA 3TG5A 2IGQA 3BO5A 3RIBA 4QEOA 3K5KA 3OOIA 5EX3A 5CPRB 3S7BA 4JDSA 3N71A 3RJWA 1ZKKA 4C1QA 5TEGA 4NVQA 5T0MA 2RFIA 3M59A 4BUPA 3M55A 3RQ4A 4WUYA 1H3IA 5AYFA 3VV0A 5CCMA 3M56A 5T0KA 4I51A 3M53A 5CCLA 2W5ZA 3OPEA 4LDGA 3KMTA 3F9YA 5KJLA 3MO5A 3HNAA 5F6LA 4QENA 4MI0A 3QWVA 1MT6A 3RAYA 3EP0A 4O30A 4FMUA 2W5YA 5KJMA 5JINA 5HQ8A 1N3JA 5KJKA 4YPEA 4J7IA 3M57A 3KMJA 5F59A 3DB5A 4MI5A 4QEPA 3MO2A 3M54A 1O9SA 2F69A 4YPAA 5ARFA 3MO0A 5LSXA 3OXGA 4O6FA 3S7DA 3F9XA 4JLGA 2JV0A 4AU7A 4J83A 1PEGA 3KMAA 4NJ5A 4IJDA 4Z4PA 3VUZA 1N6CA 3OS5A 2BQZA 1MUFA 4J7FA 4H12A 4YNPA 3M5AA 2G46A 3OXFA 3S7JA 5JHNA 5F6KC 3DALA 2R3AA 3CBPA
chains in the Genus database with same CATH superfamily
3QWWA 1MVHA 1MVXA 3CBOA 5JIYA 2O8JA 3S8PA 3F9WA 1XQHA 4E47A 1ML9A 1N6AA 3QWPA 3OXLA 5TTFA 5KJNA 4RZ0A 5T5GA 2QPWA 5HI7A 3F9ZA 3M58A 5F5EA 4J8OA 4IJ8A 3MEKA 3TG4A 5EX0A 3IHXA 5ARGA 3S7FA 5EG2A 3SWCA 4YPUA 3RU0A 3CBMA 3PDNA 5LSZA 4YNDA 5JJ0A 5TH7A 3SW9A 3FPDA 4YNMA 3TG5A 2IGQA 3BO5A 3RIBA 4QEOA 3K5KA 3OOIA 5EX3A 5CPRB 3S7BA 4JDSA 3N71A 3RJWA 1ZKKA 4C1QA 5TEGA 4NVQA 5T0MA 2RFIA 3M59A 4BUPA 3M55A 3RQ4A 4WUYA 1H3IA 5AYFA 3VV0A 5CCMA 3M56A 5T0KA 4I51A 3M53A 5CCLA 2W5ZA 3OPEA 4LDGA 3KMTA 3F9YA 5KJLA 3MO5A 3HNAA 5F6LA 4QENA 4MI0A 3QWVA 1MT6A 3RAYA 3EP0A 4O30A 4FMUA 2W5YA 5KJMA 5JINA 5HQ8A 1N3JA 5KJKA 4YPEA 4J7IA 3M57A 3KMJA 5F59A 3DB5A 4MI5A 4QEPA 3MO2A 3M54A 1O9SA 2F69A 4YPAA 5ARFA 3MO0A 5LSXA 3OXGA 4O6FA 3S7DA 3F9XA 4JLGA 2JV0A 4AU7A 4J83A 1PEGA 3KMAA 4NJ5A 4IJDA 4Z4PA 3VUZA 1N6CA 3OS5A 2BQZA 1MUFA 4J7FA 4H12A 4YNPA 3M5AA 2G46A 3OXFA 3S7JA 5JHNA 5F6KC 3DALA 2R3AA 3CBPA
chains in the Genus database with same CATH topology
3QWWA 1MVHA 1MVXA 3CBOA 5JIYA 2O8JA 3S8PA 3F9WA 1XQHA 4E47A 1ML9A 1N6AA 3QWPA 3OXLA 5TTFA 5KJNA 4RZ0A 5T5GA 2QPWA 5HI7A 3F9ZA 3M58A 5F5EA 4J8OA 4IJ8A 3MEKA 3TG4A 5EX0A 3IHXA 5ARGA 3S7FA 5EG2A 3SWCA 4YPUA 3RU0A 3CBMA 3PDNA 5LSZA 4YNDA 5JJ0A 5TH7A 3SW9A 3FPDA 4YNMA 3TG5A 2IGQA 3BO5A 3RIBA 4QEOA 3K5KA 3OOIA 5EX3A 5CPRB 3S7BA 4JDSA 3N71A 3RJWA 1ZKKA 4C1QA 5TEGA 4NVQA 5T0MA 2RFIA 3M59A 4BUPA 3M55A 3RQ4A 4WUYA 1H3IA 5AYFA 3VV0A 5CCMA 3M56A 5T0KA 4I51A 3M53A 5CCLA 2W5ZA 3OPEA 4LDGA 3KMTA 3F9YA 5KJLA 3MO5A 3HNAA 5F6LA 4QENA 4MI0A 3QWVA 1MT6A 3RAYA 3EP0A 4O30A 4FMUA 2W5YA 5KJMA 5JINA 5HQ8A 1N3JA 5KJKA 4YPEA 4J7IA 3M57A 3KMJA 5F59A 3DB5A 4MI5A 4QEPA 3MO2A 3M54A 1O9SA 2F69A 4YPAA 5ARFA 3MO0A 5LSXA 3OXGA 4O6FA 3S7DA 3F9XA 4JLGA 2JV0A 4AU7A 4J83A 1PEGA 3KMAA 4NJ5A 4IJDA 4Z4PA 3VUZA 1N6CA 3OS5A 2BQZA 1MUFA 4J7FA 4H12A 4YNPA 3M5AA 2G46A 3OXFA 3S7JA 5JHNA 5F6KC 3DALA 2R3AA 3CBPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QWW A;  1MVH A;  1MVX A;  3CBO A;  5JIY A;  2O8J A;  3S8P A;  3F9W A;  1XQH A;  4E47 A;  1ML9 A;  1N6A A;  3QWP A;  3OXL A;  5TTF A;  5KJN A;  4RZ0 A;  5T5G A;  2QPW A;  5HI7 A;  3F9Z A;  3M58 A;  5F5E A;  4J8O A;  4IJ8 A;  3MEK A;  3TG4 A;  5EX0 A;  3IHX A;  5ARG A;  3S7F A;  5EG2 A;  3SWC A;  4YPU A;  3RU0 A;  3CBM A;  3PDN A;  5LSZ A;  4YND A;  5JJ0 A;  5TH7 A;  3SW9 A;  3FPD A;  4YNM A;  3TG5 A;  2IGQ A;  3BO5 A;  3RIB A;  4QEO A;  3K5K A;  3OOI A;  5EX3 A;  5CPR B;  3S7B A;  4JDS A;  3N71 A;  3RJW A;  1ZKK A;  4C1Q A;  5TEG A;  4NVQ A;  5T0M A;  2RFI A;  3M59 A;  4BUP A;  3M55 A;  3RQ4 A;  4WUY A;  1H3I A;  5AYF A;  3VV0 A;  5CCM A;  3M56 A;  5T0K A;  4I51 A;  3M53 A;  5CCL A;  2W5Z A;  3OPE A;  4LDG A;  3KMT A;  3F9Y A;  5KJL A;  3MO5 A;  3HNA A;  5F6L A;  4QEN A;  4MI0 A;  3QWV A;  1MT6 A;  3RAY A;  3EP0 A;  4O30 A;  4FMU A;  2W5Y A;  5KJM A;  5JIN A;  5HQ8 A;  1N3J A;  5KJK A;  4YPE A;  4J7I A;  3M57 A;  3KMJ A;  5F59 A;  3DB5 A;  4MI5 A;  4QEP A;  3MO2 A;  3M54 A;  1O9S A;  2F69 A;  4YPA A;  5ARF A;  3MO0 A;  5LSX A;  3OXG A;  4O6F A;  3S7D A;  3F9X A;  4JLG A;  2JV0 A;  4AU7 A;  4J83 A;  1PEG A;  3KMA A;  4NJ5 A;  4IJD A;  4Z4P A;  3VUZ A;  1N6C A;  3OS5 A;  2BQZ A;  1MUF A;  4J7F A;  4H12 A;  4YNP A;  3M5A A;  2G46 A;  3OXF A;  3S7J A;  5JHN A;  5F6K C;  3DAL A;  2R3A A;  3CBP A; 
#chains in the Genus database with same CATH topology
 3QWW A;  1MVH A;  1MVX A;  3CBO A;  5JIY A;  2O8J A;  3S8P A;  3F9W A;  1XQH A;  4E47 A;  1ML9 A;  1N6A A;  3QWP A;  3OXL A;  5TTF A;  5KJN A;  4RZ0 A;  5T5G A;  2QPW A;  5HI7 A;  3F9Z A;  3M58 A;  5F5E A;  4J8O A;  4IJ8 A;  3MEK A;  3TG4 A;  5EX0 A;  3IHX A;  5ARG A;  3S7F A;  5EG2 A;  3SWC A;  4YPU A;  3RU0 A;  3CBM A;  3PDN A;  5LSZ A;  4YND A;  5JJ0 A;  5TH7 A;  3SW9 A;  3FPD A;  4YNM A;  3TG5 A;  2IGQ A;  3BO5 A;  3RIB A;  4QEO A;  3K5K A;  3OOI A;  5EX3 A;  5CPR B;  3S7B A;  4JDS A;  3N71 A;  3RJW A;  1ZKK A;  4C1Q A;  5TEG A;  4NVQ A;  5T0M A;  2RFI A;  3M59 A;  4BUP A;  3M55 A;  3RQ4 A;  4WUY A;  1H3I A;  5AYF A;  3VV0 A;  5CCM A;  3M56 A;  5T0K A;  4I51 A;  3M53 A;  5CCL A;  2W5Z A;  3OPE A;  4LDG A;  3KMT A;  3F9Y A;  5KJL A;  3MO5 A;  3HNA A;  5F6L A;  4QEN A;  4MI0 A;  3QWV A;  1MT6 A;  3RAY A;  3EP0 A;  4O30 A;  4FMU A;  2W5Y A;  5KJM A;  5JIN A;  5HQ8 A;  1N3J A;  5KJK A;  4YPE A;  4J7I A;  3M57 A;  3KMJ A;  5F59 A;  3DB5 A;  4MI5 A;  4QEP A;  3MO2 A;  3M54 A;  1O9S A;  2F69 A;  4YPA A;  5ARF A;  3MO0 A;  5LSX A;  3OXG A;  4O6F A;  3S7D A;  3F9X A;  4JLG A;  2JV0 A;  4AU7 A;  4J83 A;  1PEG A;  3KMA A;  4NJ5 A;  4IJD A;  4Z4P A;  3VUZ A;  1N6C A;  3OS5 A;  2BQZ A;  1MUF A;  4J7F A;  4H12 A;  4YNP A;  3M5A A;  2G46 A;  3OXF A;  3S7J A;  5JHN A;  5F6K C;  3DAL A;  2R3A A;  3CBP A; 
#chains in the Genus database with same CATH homology
 3QWW A;  1MVH A;  1MVX A;  3CBO A;  5JIY A;  2O8J A;  3S8P A;  3F9W A;  1XQH A;  4E47 A;  1ML9 A;  1N6A A;  3QWP A;  3OXL A;  5TTF A;  5KJN A;  4RZ0 A;  5T5G A;  2QPW A;  5HI7 A;  3F9Z A;  3M58 A;  5F5E A;  4J8O A;  4IJ8 A;  3MEK A;  3TG4 A;  5EX0 A;  3IHX A;  5ARG A;  3S7F A;  5EG2 A;  3SWC A;  4YPU A;  3RU0 A;  3CBM A;  3PDN A;  5LSZ A;  4YND A;  5JJ0 A;  5TH7 A;  3SW9 A;  3FPD A;  4YNM A;  3TG5 A;  2IGQ A;  3BO5 A;  3RIB A;  4QEO A;  3K5K A;  3OOI A;  5EX3 A;  5CPR B;  3S7B A;  4JDS A;  3N71 A;  3RJW A;  1ZKK A;  4C1Q A;  5TEG A;  4NVQ A;  5T0M A;  2RFI A;  3M59 A;  4BUP A;  3M55 A;  3RQ4 A;  4WUY A;  1H3I A;  5AYF A;  3VV0 A;  5CCM A;  3M56 A;  5T0K A;  4I51 A;  3M53 A;  5CCL A;  2W5Z A;  3OPE A;  4LDG A;  3KMT A;  3F9Y A;  5KJL A;  3MO5 A;  3HNA A;  5F6L A;  4QEN A;  4MI0 A;  3QWV A;  1MT6 A;  3RAY A;  3EP0 A;  4O30 A;  4FMU A;  2W5Y A;  5KJM A;  5JIN A;  5HQ8 A;  1N3J A;  5KJK A;  4YPE A;  4J7I A;  3M57 A;  3KMJ A;  5F59 A;  3DB5 A;  4MI5 A;  4QEP A;  3MO2 A;  3M54 A;  1O9S A;  2F69 A;  4YPA A;  5ARF A;  3MO0 A;  5LSX A;  3OXG A;  4O6F A;  3S7D A;  3F9X A;  4JLG A;  2JV0 A;  4AU7 A;  4J83 A;  1PEG A;  3KMA A;  4NJ5 A;  4IJD A;  4Z4P A;  3VUZ A;  1N6C A;  3OS5 A;  2BQZ A;  1MUF A;  4J7F A;  4H12 A;  4YNP A;  3M5A A;  2G46 A;  3OXF A;  3S7J A;  5JHN A;  5F6K C;  3DAL A;  2R3A A;  3CBP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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