1NL1A

Bovine prothrombin fragment 1 in complex with calcium ion
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
147
structure length
137
Chain Sequence
ANKGFLVRKGNLRCLPCSRAFALSLSATDAFWAKYTACESARNPREKLNECLEGNCAEGVGMNYRGNVSVTRSGIECQLWRSRYPHKPEINSTTHPGADLRENFCRNPDGSITGPWCYTTSPTLRREECSVPVCGQD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords Prothrombin
publication title Structural basis of membrane binding by Gla domains of vitamin K-dependent proteins.
pubmed doi rcsb
total genus 36
structure length 137
sequence length 147
ec nomenclature ec 3.4.21.5: Thrombin.
pdb deposition date 2003-01-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00051 Kringle Kringle domain
A PF00594 Gla Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.20.10 Mainly Beta Beta Barrel Plasminogen Kringle 4 Plasminogen Kringle 4 1nl1A00
4O03A 1NL2A 3K65A 5COEA 2K4RA 3U73A 4D3CA 5CSQA 1KIVA 1TPKA 2HPQP 4BV7A 2SPTA 5CT1A 1HPJA 5CS1A 1PMLA 4A5TS 2PF1A 5CS3A 1A0HA 1PMKA 5CS9A 3KIVA 1CEBA 1I71A 2FEBA 4BVCA 3MKPA 2HPPP 2DOHX 1KDUA 3HN4A 1GMOA 2I9BA 4BVWA 1KI0A 3E6PL 3SP8A 2K51A 1JFNA 3BT1A 1BHTA 4DURA 1PK4A 2PK4A 3BT2A 5HPGA 4NZQA 1CEAA 1HPKA 1PKRA 4HZHA 5CT2A 4IUAA 1URKA 2FD6A 3NXPA 1KRNA 5CP9A 1NK1A 2KNFA 4KIVA 4CIKA 2L0SA 5CS5A 4BVDA 2QJ2A 2PF2A 3LAQA 1GMNA 2KJ4A 4BVVA 2DOIA 5CT3A 1GP9A 1B2IA 2QJ4A 2I9AA 4BV5A 1I5KA 1PK2A 1NL1A
chains in the Genus database with same CATH superfamily
4O03A 1NL2A 3K65A 5COEA 2K4RA 3U73A 4D3CA 5CSQA 1KIVA 1TPKA 2HPQP 4BV7A 2SPTA 5CT1A 1HPJA 5CS1A 1PMLA 4A5TS 2PF1A 5CS3A 1A0HA 1PMKA 5CS9A 3KIVA 1CEBA 1I71A 2FEBA 4BVCA 3MKPA 2HPPP 2DOHX 1KDUA 3HN4A 1GMOA 2I9BA 4BVWA 1KI0A 3E6PL 3SP8A 2K51A 1JFNA 3BT1A 1BHTA 4DURA 1PK4A 2PK4A 3BT2A 5HPGA 4NZQA 1CEAA 1HPKA 1PKRA 4HZHA 5CT2A 4IUAA 1URKA 2FD6A 3NXPA 1KRNA 5CP9A 1NK1A 2KNFA 4KIVA 4CIKA 2L0SA 5CS5A 4BVDA 2QJ2A 2PF2A 3LAQA 1GMNA 2KJ4A 4BVVA 2DOIA 5CT3A 1GP9A 1B2IA 2QJ4A 2I9AA 4BV5A 1I5KA 1PK2A 1NL1A
chains in the Genus database with same CATH topology
4O03A 1NL2A 3K65A 5COEA 2K4RA 3U73A 4D3CA 5CSQA 1KIVA 1TPKA 2HPQP 4BV7A 2SPTA 5CT1A 1HPJA 5CS1A 1PMLA 4A5TS 2PF1A 5CS3A 1A0HA 1PMKA 5CS9A 3KIVA 1CEBA 1I71A 2FEBA 4BVCA 3MKPA 2HPPP 2DOHX 1KDUA 3HN4A 1GMOA 2I9BA 4BVWA 1KI0A 3E6PL 3SP8A 2K51A 1JFNA 3BT1A 1BHTA 4DURA 1PK4A 2PK4A 3BT2A 5HPGA 4NZQA 1CEAA 1HPKA 1PKRA 4HZHA 5CT2A 4IUAA 1URKA 2FD6A 3NXPA 1KRNA 5CP9A 1NK1A 2KNFA 4KIVA 4CIKA 2L0SA 5CS5A 4BVDA 2QJ2A 2PF2A 3LAQA 1GMNA 2KJ4A 4BVVA 2DOIA 5CT3A 1GP9A 1B2IA 2QJ4A 2I9AA 4BV5A 1I5KA 1PK2A 1NL1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4O03 A;  1NL2 A;  3K65 A;  5COE A;  2K4R A;  3U73 A;  4D3C A;  5CSQ A;  1KIV A;  1TPK A;  2HPQ P;  4BV7 A;  2SPT A;  5CT1 A;  1HPJ A;  5CS1 A;  1PML A;  4A5T S;  2PF1 A;  5CS3 A;  1A0H A;  1PMK A;  5CS9 A;  3KIV A;  1CEB A;  1I71 A;  2FEB A;  4BVC A;  3MKP A;  2HPP P;  2DOH X;  1KDU A;  3HN4 A;  1GMO A;  2I9B A;  4BVW A;  1KI0 A;  3E6P L;  3SP8 A;  2K51 A;  1JFN A;  3BT1 A;  1BHT A;  4DUR A;  1PK4 A;  2PK4 A;  3BT2 A;  5HPG A;  4NZQ A;  1CEA A;  1HPK A;  1PKR A;  4HZH A;  5CT2 A;  4IUA A;  1URK A;  2FD6 A;  3NXP A;  1KRN A;  5CP9 A;  1NK1 A;  2KNF A;  4KIV A;  4CIK A;  2L0S A;  5CS5 A;  4BVD A;  2QJ2 A;  2PF2 A;  3LAQ A;  1GMN A;  2KJ4 A;  4BVV A;  2DOI A;  5CT3 A;  1GP9 A;  1B2I A;  2QJ4 A;  2I9A A;  4BV5 A;  1I5K A;  1PK2 A;  1NL1 A; 
#chains in the Genus database with same CATH topology
 4O03 A;  1NL2 A;  3K65 A;  5COE A;  2K4R A;  3U73 A;  4D3C A;  5CSQ A;  1KIV A;  1TPK A;  2HPQ P;  4BV7 A;  2SPT A;  5CT1 A;  1HPJ A;  5CS1 A;  1PML A;  4A5T S;  2PF1 A;  5CS3 A;  1A0H A;  1PMK A;  5CS9 A;  3KIV A;  1CEB A;  1I71 A;  2FEB A;  4BVC A;  3MKP A;  2HPP P;  2DOH X;  1KDU A;  3HN4 A;  1GMO A;  2I9B A;  4BVW A;  1KI0 A;  3E6P L;  3SP8 A;  2K51 A;  1JFN A;  3BT1 A;  1BHT A;  4DUR A;  1PK4 A;  2PK4 A;  3BT2 A;  5HPG A;  4NZQ A;  1CEA A;  1HPK A;  1PKR A;  4HZH A;  5CT2 A;  4IUA A;  1URK A;  2FD6 A;  3NXP A;  1KRN A;  5CP9 A;  1NK1 A;  2KNF A;  4KIV A;  4CIK A;  2L0S A;  5CS5 A;  4BVD A;  2QJ2 A;  2PF2 A;  3LAQ A;  1GMN A;  2KJ4 A;  4BVV A;  2DOI A;  5CT3 A;  1GP9 A;  1B2I A;  2QJ4 A;  2I9A A;  4BV5 A;  1I5K A;  1PK2 A;  1NL1 A; 
#chains in the Genus database with same CATH homology
 4O03 A;  1NL2 A;  3K65 A;  5COE A;  2K4R A;  3U73 A;  4D3C A;  5CSQ A;  1KIV A;  1TPK A;  2HPQ P;  4BV7 A;  2SPT A;  5CT1 A;  1HPJ A;  5CS1 A;  1PML A;  4A5T S;  2PF1 A;  5CS3 A;  1A0H A;  1PMK A;  5CS9 A;  3KIV A;  1CEB A;  1I71 A;  2FEB A;  4BVC A;  3MKP A;  2HPP P;  2DOH X;  1KDU A;  3HN4 A;  1GMO A;  2I9B A;  4BVW A;  1KI0 A;  3E6P L;  3SP8 A;  2K51 A;  1JFN A;  3BT1 A;  1BHT A;  4DUR A;  1PK4 A;  2PK4 A;  3BT2 A;  5HPG A;  4NZQ A;  1CEA A;  1HPK A;  1PKR A;  4HZH A;  5CT2 A;  4IUA A;  1URK A;  2FD6 A;  3NXP A;  1KRN A;  5CP9 A;  1NK1 A;  2KNF A;  4KIV A;  4CIK A;  2L0S A;  5CS5 A;  4BVD A;  2QJ2 A;  2PF2 A;  3LAQ A;  1GMN A;  2KJ4 A;  4BVV A;  2DOI A;  5CT3 A;  1GP9 A;  1B2I A;  2QJ4 A;  2I9A A;  4BV5 A;  1I5K A;  1PK2 A;  1NL1 A; 
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#similar chains, but unknotted
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