1NL2A

Bovine prothrombin fragment 1 in complex with calcium and lysophosphotidylserine
Total Genus 34
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
34
sequence length
146
structure length
136
Chain Sequence
ANKGFLVRKGNLRCLPCSRAFALSLSATDAFWAKYTACESARNPREKLNECLEGNCAEGVGMNYRGNVSVTRSGIECQLWRSRYPHKPEINSTTHPGADLRENFCRNPDGSITGPWCYTTSPTLRREECSVPVCGQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords Prothrombin
publication title Structural basis of membrane binding by Gla domains of vitamin K-dependent proteins.
pubmed doi rcsb
total genus 34
structure length 136
sequence length 146
ec nomenclature ec 3.4.21.5: Thrombin.
pdb deposition date 2003-01-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00051 Kringle Kringle domain
A PF00594 Gla Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.20.10 Mainly Beta Beta Barrel Plasminogen Kringle 4 Plasminogen Kringle 4 1nl2A00
2QJ2A 2PF1A 4KIVA 4BVCA 1PK2A 3NXPA 4A5TS 2FEBA 5CP9A 5HPGA 5CS3A 4BV7A 5CT2A 2I9AA 1KIVA 5CS1A 4CIKA 1NL2A 2HPQP 1CEBA 2QJ4A 2L0SA 5CS9A 1KI0A 1KRNA 2KNFA 1GMNA 2FD6A 2KJ4A 3K65A 3E6PL 1I5KA 1PMLA 1KDUA 2HPPP 4IUAA 1PKRA 3SP8A 4BV5A 2SPTA 1I71A 1BHTA 2I9BA 4D3CA 3U73A 1A0HA 3HN4A 3BT1A 3LAQA 2PK4A 2K51A 1GMOA 1GP9A 4O03A 4BVVA 1PK4A 1HPJA 2DOIA 5CT1A 5CS5A 1B2IA 1NL1A 1NK1A 4HZHA 5CSQA 1JFNA 1URKA 4BVWA 1PMKA 1HPKA 2DOHX 4DURA 3KIVA 2K4RA 3MKPA 4NZQA 4BVDA 5COEA 1TPKA 1CEAA 2PF2A 5CT3A 3BT2A
chains in the Genus database with same CATH superfamily
2QJ2A 2PF1A 4KIVA 4BVCA 1PK2A 3NXPA 4A5TS 2FEBA 5CP9A 5HPGA 5CS3A 4BV7A 5CT2A 2I9AA 1KIVA 5CS1A 4CIKA 1NL2A 2HPQP 1CEBA 2QJ4A 2L0SA 5CS9A 1KI0A 1KRNA 2KNFA 1GMNA 2FD6A 2KJ4A 3K65A 3E6PL 1I5KA 1PMLA 1KDUA 2HPPP 4IUAA 1PKRA 3SP8A 4BV5A 2SPTA 1I71A 1BHTA 2I9BA 4D3CA 3U73A 1A0HA 3HN4A 3BT1A 3LAQA 2PK4A 2K51A 1GMOA 1GP9A 4O03A 4BVVA 1PK4A 1HPJA 2DOIA 5CT1A 5CS5A 1B2IA 1NL1A 1NK1A 4HZHA 5CSQA 1JFNA 1URKA 4BVWA 1PMKA 1HPKA 2DOHX 4DURA 3KIVA 2K4RA 3MKPA 4NZQA 4BVDA 5COEA 1TPKA 1CEAA 2PF2A 5CT3A 3BT2A
chains in the Genus database with same CATH topology
2QJ2A 2PF1A 4KIVA 4BVCA 1PK2A 3NXPA 4A5TS 2FEBA 5CP9A 5HPGA 5CS3A 4BV7A 5CT2A 2I9AA 1KIVA 5CS1A 4CIKA 1NL2A 2HPQP 1CEBA 2QJ4A 2L0SA 5CS9A 1KI0A 1KRNA 2KNFA 1GMNA 2FD6A 2KJ4A 3K65A 3E6PL 1I5KA 1PMLA 1KDUA 2HPPP 4IUAA 1PKRA 3SP8A 4BV5A 2SPTA 1I71A 1BHTA 2I9BA 4D3CA 3U73A 1A0HA 3HN4A 3BT1A 3LAQA 2PK4A 2K51A 1GMOA 1GP9A 4O03A 4BVVA 1PK4A 1HPJA 2DOIA 5CT1A 5CS5A 1B2IA 1NL1A 1NK1A 4HZHA 5CSQA 1JFNA 1URKA 4BVWA 1PMKA 1HPKA 2DOHX 4DURA 3KIVA 2K4RA 3MKPA 4NZQA 4BVDA 5COEA 1TPKA 1CEAA 2PF2A 5CT3A 3BT2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QJ2 A;  2PF1 A;  4KIV A;  4BVC A;  1PK2 A;  3NXP A;  4A5T S;  2FEB A;  5CP9 A;  5HPG A;  5CS3 A;  4BV7 A;  5CT2 A;  2I9A A;  1KIV A;  5CS1 A;  4CIK A;  1NL2 A;  2HPQ P;  1CEB A;  2QJ4 A;  2L0S A;  5CS9 A;  1KI0 A;  1KRN A;  2KNF A;  1GMN A;  2FD6 A;  2KJ4 A;  3K65 A;  3E6P L;  1I5K A;  1PML A;  1KDU A;  2HPP P;  4IUA A;  1PKR A;  3SP8 A;  4BV5 A;  2SPT A;  1I71 A;  1BHT A;  2I9B A;  4D3C A;  3U73 A;  1A0H A;  3HN4 A;  3BT1 A;  3LAQ A;  2PK4 A;  2K51 A;  1GMO A;  1GP9 A;  4O03 A;  4BVV A;  1PK4 A;  1HPJ A;  2DOI A;  5CT1 A;  5CS5 A;  1B2I A;  1NL1 A;  1NK1 A;  4HZH A;  5CSQ A;  1JFN A;  1URK A;  4BVW A;  1PMK A;  1HPK A;  2DOH X;  4DUR A;  3KIV A;  2K4R A;  3MKP A;  4NZQ A;  4BVD A;  5COE A;  1TPK A;  1CEA A;  2PF2 A;  5CT3 A;  3BT2 A; 
#chains in the Genus database with same CATH topology
 2QJ2 A;  2PF1 A;  4KIV A;  4BVC A;  1PK2 A;  3NXP A;  4A5T S;  2FEB A;  5CP9 A;  5HPG A;  5CS3 A;  4BV7 A;  5CT2 A;  2I9A A;  1KIV A;  5CS1 A;  4CIK A;  1NL2 A;  2HPQ P;  1CEB A;  2QJ4 A;  2L0S A;  5CS9 A;  1KI0 A;  1KRN A;  2KNF A;  1GMN A;  2FD6 A;  2KJ4 A;  3K65 A;  3E6P L;  1I5K A;  1PML A;  1KDU A;  2HPP P;  4IUA A;  1PKR A;  3SP8 A;  4BV5 A;  2SPT A;  1I71 A;  1BHT A;  2I9B A;  4D3C A;  3U73 A;  1A0H A;  3HN4 A;  3BT1 A;  3LAQ A;  2PK4 A;  2K51 A;  1GMO A;  1GP9 A;  4O03 A;  4BVV A;  1PK4 A;  1HPJ A;  2DOI A;  5CT1 A;  5CS5 A;  1B2I A;  1NL1 A;  1NK1 A;  4HZH A;  5CSQ A;  1JFN A;  1URK A;  4BVW A;  1PMK A;  1HPK A;  2DOH X;  4DUR A;  3KIV A;  2K4R A;  3MKP A;  4NZQ A;  4BVD A;  5COE A;  1TPK A;  1CEA A;  2PF2 A;  5CT3 A;  3BT2 A; 
#chains in the Genus database with same CATH homology
 2QJ2 A;  2PF1 A;  4KIV A;  4BVC A;  1PK2 A;  3NXP A;  4A5T S;  2FEB A;  5CP9 A;  5HPG A;  5CS3 A;  4BV7 A;  5CT2 A;  2I9A A;  1KIV A;  5CS1 A;  4CIK A;  1NL2 A;  2HPQ P;  1CEB A;  2QJ4 A;  2L0S A;  5CS9 A;  1KI0 A;  1KRN A;  2KNF A;  1GMN A;  2FD6 A;  2KJ4 A;  3K65 A;  3E6P L;  1I5K A;  1PML A;  1KDU A;  2HPP P;  4IUA A;  1PKR A;  3SP8 A;  4BV5 A;  2SPT A;  1I71 A;  1BHT A;  2I9B A;  4D3C A;  3U73 A;  1A0H A;  3HN4 A;  3BT1 A;  3LAQ A;  2PK4 A;  2K51 A;  1GMO A;  1GP9 A;  4O03 A;  4BVV A;  1PK4 A;  1HPJ A;  2DOI A;  5CT1 A;  5CS5 A;  1B2I A;  1NL1 A;  1NK1 A;  4HZH A;  5CSQ A;  1JFN A;  1URK A;  4BVW A;  1PMK A;  1HPK A;  2DOH X;  4DUR A;  3KIV A;  2K4R A;  3MKP A;  4NZQ A;  4BVD A;  5COE A;  1TPK A;  1CEA A;  2PF2 A;  5CT3 A;  3BT2 A; 
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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