1NWLA

Crystal structure of the ptp1b complexed with sp7343-sp7964, a ptyr mimetic
Total Genus 96
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
96
sequence length
283
structure length
283
Chain Sequence
MEMEKEFEQIDKSGSWAAIYQDIRHEASDFPSRVAKLPKNKNRNRYCDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTVGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery of a New Phosphotyrosine Mimetic for PTP1B Using Breakaway Tethering
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords protein-tyrosine phosphatase, non-receptor type 1
total genus 96
structure length 283
sequence length 283
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2003-02-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 1nwlA00
1A5YA 4YAAA 2Y2FA 3F9BA 2FH7A 4GWFA 1ZCKA 4KYQA 4D3RA 1OETA 4ZI4A 3ZMQA 3SMEA 3QCMA 3QKQA 4HRFA 3CM3A 1G7FA 3RO1A 3V0GA 2QDCA 5MMZB 3B7OA 2HCMA 3O3LA 3F9AA 2C46A 3MMJA 3V0IA 1PXHA 4R0TA 2CM3A 1V3AA 2H4GA 5KA3A 2G6ZA 2OOQA 1WRMA 3A5JA 3QCBA 1GWZA 4B04A 2RF6A 2C7SA 2HXPA 2J17A 1Q6SA 2PI7A 5K25A 1Q6TA 3D44A 4GFVA 1YFOA 2I6IA 2I6OA 2I4EA 4JMKA 2ZN7A 2CMBA 1YTNA 5KA1A 4GS0A 1G4US 1GFYA 3N0AA 4NNDA 4AZ1A 3ZM1A 4QBEA 4QAPA 4Y14A 3S3KA 5K22A 3I36A 3ZM2A 5KA0A 1MKPA 1OEUA 2CNEA 1L8KA 5KA9A 2F6WA 1FPRA 3V0JA 1PH0A 2VEUA 4R30A 3LJ8A 1PTVA 2B4SA 1L8GA 4D3QA 4WOHA 3BRHA 1AAXA 2F6FA 4PVGA 2OC3A 3S3EA 2QDMA 3S3HA 2G59A 1JF7A 4DGXA 3QCKA 5KAAA 3A5KA 2CNIA 1PTUA 4OHHA 4NWGA 2FJNA 5AWXA 1NWEA 3RGQA 2CM2A 2QCJA 4I8NA 4GFUA 2VEVA 5HDEA 1D5RA 2QBPA 2VEXA 1PTTA 5GTJA 1T49A 2F6YA 3F41A 5K9WA 1G7GA 3QCFA 2ZMMA 1XXVA 2HC1A 2I6PA 2CMAA 1Q6JA 2CM7A 4QUMA 4GE2A 3QCIA 2B4PA 1G1HA 3I80A 3V0EA 2ESBA 4WU2A 3S3FA 3BLTA 3OLRA 1NL9A 1ZC0A 2NZ6A 4GRZA 2CM8A 2I5XA 4NWFA 3QCCA 3D42A 4RH9A 2BZLA 4D3PA 5BZZA 4WTYA 2QEPA 2P4DA 4RI5A 1YWFA 5BZXA 5LXQB 2I6JA 3SR9A 4RH5A 2HY3A 2OUDA 4QUNA 4OHLA 1QZ0A 2H02A 1PTYA 3MOZA 2WGPA 3M4UA 5IBSA 4WU3A 1I9TA 1G4WR 3EU0A 1I9SA 1XBOA 5K24A 1NWLA 1VHRA 5BX1A 2H03A 2I4GA 5IBMA 3O4UA 1OHDA 3BM8A 2PA5A 2VEYA 1OEMX 2I6MA 1C85A 2I4HA 4GRYA 4OHDA 3ZM0A 2NT7A 1ZCLA 3QCLA 3QCHA 1PYNA 1OHEA 2CNGA 4YR8B 2NTAA 3F81A 3V0DA 1R6HA 3BLUA 2CMCA 1FPZA 2CJZA 3QCDA 1WCHA 3NMEA 3GXHA 2F70A 1Q1MA 1XM2A 2B07A 2HNQA 1C87A 2I42A 3CWEA 1LQFA 2J16B 4DGPA 2NLKA 3D1OA 2M3VA 5KA7A 1XXPA 4JMJA 2QBSA 1YN9A 3QCNA 1PA9A 4JNBA 3H2XA 1LARA 2F6TA 4GE5A 3AWEA 1Q6PA 3QCGA 2PT0A 2GJTA 1PA1A 1OEOX 2GWOA 2I3UA 4R0SA 2A3KA 5KABA 5KACA 1YTSA 5KADA 2I75A 4JBCA 4KYRA 1KAKA 3ZV2A 4HJQA 3O4SA 2GP0A 2BGDA 4Y2EA 2CFVA 1YGRA 2H4VA 3S4OA 3ZM3A 1YZ4A 4MBBA 2B3OA 2HC2A 4ZN5A 5I6VA 3S4EA 3EZZA 2OZ5A 4BJOA 2Q05A 1OEVA 2QBRA 3F99A 2I3RA 1FQ1A 2YDUA 4OHIA 1NNYA 1KAVA 1YTWA 5J8RA 1J4XA 3QKPA 2H4KA 1X24A 4RI4A 5K23A 5EHRA 2F46A 2QBQA 1ECVA 3GXGA 5BUGA 1C88A 2QDPA 3I7ZA 2F6ZA 2IMGA 1C86A 2PSZA 4ZRTA 1BZHA 1NO6A 4GE6A 1XRIA 2BV5A 2HNPA 4PYHA 4ICZA 2AZRA 5KA4A 1C84A 4KI9A 2PBNA 2B4OA 3RGOA 3V0HA 2BGEA 1LYVA 1OHCA 2Q47A 1OESA 2J16A 1U25A 1WAXA 3QCEA 2FJMA 1ONYA 1EENA 4RKKA 2E0TA 3RZ2A 4NYHA 2H04A 1BZCA 4TVVA 1YGUA 2SHPA 3QCJA 4ERCA 5K9VA 5M43A 2HB1A 3D9CA 4BPCA 1U26A 3EAXA 2CNFA 1Q6MA 3U96A 1RPMA 1T4JA 2B4UA 1C83A 1RXDA 2JJDA 4QBWA 1G1FA 1QXKA 4HJPA 2B49A 2R0BA 3V0FA 2NV5A 4S0GA 3PS5A 3EB1A 4H34A 3D1HA 4QAHA 3O5XA 1JLNA 4RDDA 2A8BA 1G1GA 4NX8A 2NT2A 2F71A 1SUGA 2DXPA 1T48A 3AWGA 2MBCA 1NZ7A 5EHPA 2QCTA 1M3GA 3EMUA 3MOWA 4Z6BA 1Q6NA 2HVLA 3D1QA 3OMHA 3AWFA 5KA8A 4RHGA 1ZZWA 1BZJA 4OHEA 3O4TA 1I57A 4J51A 2P6XA 4IKCA 2Y96A 3ZMPA 2CNHA 1ONZA 2VEWA 2F6VA 1U24A 2I1YA 4H1OA 2BIJA 5KA2A 2PQ5A 1EEOA 1P15A 1YPTA 2AHSA
chains in the Genus database with same CATH superfamily
1A5YA 2GCBA 4YAAA 2Y2FA 3F9BA 2FH7A 4GWFA 1ZCKA 4KYQA 4D3RA 1OETA 4ZI4A 3ZMQA 4CVMA 3SMEA 3QCMA 3QKQA 4HRFA 3CM3A 1G7FA 3RO1A 3V0GA 2QDCA 5MMZB 3B7OA 2HCMA 3O3LA 3F9AA 2C46A 3MMJA 3V0IA 3N2AA 1PXHA 2GCAA 4R0TA 2CM3A 2VTDA 1O5ZA 1V3AA 2H4GA 5KA3A 3QCZA 2G6ZA 2OOQA 1WRMA 3A5JA 3QCBA 1GWZA 4B04A 2WJPA 2RF6A 2C7SA 2HXPA 2J17A 1Q6SA 2PI7A 5K25A 2AM2A 1Q6TA 3D44A 4GFVA 1YFOA 2I6IA 3NRSA 2I6OA 2Y67A 2I4EA 4JMKA 2ZN7A 2CMBA 1YTNA 4ZIYA 5KA1A 4GS0A 1G4US 1GFYA 3N0AA 4NNDA 4AZ1A 3ZM1A 4QBEA 4QAPA 4Y14A 3S3KA 5K22A 3I36A 3ZM2A 5KA0A 1MKPA 1OEUA 2CNEA 1L8KA 5KA9A 1GG4A 2F00A 2F6WA 1FPRA 3V0JA 1PH0A 2VEUA 4R30A 3ZM5A 3LJ8A 1PTVA 1GQQA 2B4SA 1L8GA 4D3QA 4HV4A 4WOHA 4CVKA 3BRHA 1P3DA 1AAXA 2F6FA 1JBVA 4PVGA 2OC3A 3S3EA 2QDMA 3S3HA 2G59A 1JF7A 4DGXA 3QCKA 5KAAA 3A5KA 2CNIA 2UUOA 1PTUA 1P31A 4OHHA 4NWGA 2FJNA 5AWXA 1NWEA 4UAGA 2CM2A 3RGQA 2QCJA 4I8NA 4GFUA 2VEVA 5HDEA 1D5RA 2QBPA 2VEXA 1PTTA 5GTJA 1T49A 2F6YA 3F41A 5K9WA 1G7GA 3QCFA 3MVNA 2ZMMA 1XXVA 2HC1A 2I6PA 2CMAA 1Q6JA 2CM7A 4QUMA 3LK7A 4GE2A 3HN7A 3QCIA 2B4PA 1G1HA 3I80A 2VOSA 3V0EA 2ESBA 4WU2A 3S3FA 3BLTA 3OLRA 1NL9A 1ZC0A 2NZ6A 4GRZA 2CM8A 2I5XA 4NWFA 3QCCA 4CVLA 3D42A 4RH9A 2BZLA 4D3PA 5BZZA 4WTYA 2QEPA 2P4DA 4RI5A 1YWFA 5BZXA 5LXQB 2I6JA 3SR9A 4RH5A 2HY3A 2OUDA 2WTZA 4QUNA 2JFFA 4OHLA 2VORA 1QZ0A 2H02A 1PTYA 4QDIA 3MOZA 2WGPA 3M4UA 5IBSA 4WU3A 1EEHA 1I9TA 1G4WR 3EU0A 1I9SA 1XBOA 5K24A 1NWLA 1VHRA 5BX1A 2H03A 2I4GA 3UAGA 5IBMA 3O4UA 1OHDA 3BM8A 2PA5A 2VEYA 4C13A 1OEMX 2I6MA 1C85A 2I4HA 4GRYA 4OHDA 3ZM0A 2NT7A 4QF5A 3ZM6A 1ZCLA 3QCLA 3QCHA 1PYNA 1UAGA 1OHEA 2CNGA 4YR8B 2NTAA 3F81A 3V0DA 1R6HA 3BLUA 2CMCA 1FPZA 2CJZA 3QCDA 2JFHA 1WCHA 3NMEA 3GXHA 2F70A 1Q1MA 1XM2A 2B07A 2HNQA 1C87A 2I42A 3CWEA 1LQFA 2J16B 4DGPA 2NLKA 3D1OA 2M3VA 5KA7A 1XXPA 4JMJA 2QBSA 1YN9A 3QCNA 1PA9A 4JNBA 1LARA 3H2XA 2F6TA 4BUBA 4GE5A 3AWEA 1Q6PA 3QCGA 2PT0A 2GJTA 1PA1A 1OEOX 2GWOA 2I3UA 4R0SA 2A3KA 5KABA 5KACA 1YTSA 5KADA 2I75A 4JBCA 4KYRA 1KAKA 3ZV2A 4HJQA 3O4SA 2GP0A 2BGDA 4Y2EA 2CFVA 4BUCA 1JBWA 1YGRA 2H4VA 3S4OA 3ZM3A 1YZ4A 4MBBA 2B3OA 2HC2A 4ZN5A 5I6VA 2AM1A 3S4EA 3EZZA 2OZ5A 3PYZA 2Q05A 4BJOA 1OEVA 2QBRA 3F99A 2I3RA 1FQ1A 2YDUA 2X5OA 4OHIA 1NNYA 1KAVA 1YTWA 5J8RA 1J4XA 3QKPA 2H4KA 1X24A 4RI4A 3ZL8A 5K23A 5EHRA 2F46A 2QBQA 1ECVA 3GXGA 5BUGA 1C88A 2QDPA 2Y1OA 3I7ZA 2F6ZA 2IMGA 1C86A 2Y66A 2PSZA 4ZRTA 1BZHA 1NO6A 4GE6A 1XRIA 2VTEA 2BV5A 2HNPA 4PYHA 4ICZA 2AZRA 2XJAA 1C84A 5KA4A 4KI9A 2PBNA 2B4OA 3RGOA 3V0HA 2BGEA 1LYVA 1OHCA 2Q47A 1OESA 2J16A 1U25A 1WAXA 3QCEA 2FJMA 1ONYA 1EENA 4RKKA 2E0TA 3RZ2A 4NYHA 2H04A 1BZCA 4TVVA 1YGUA 2SHPA 2Y68A 3QCJA 4ERCA 5K9VA 5M43A 2HB1A 3D9CA 4BPCA 1U26A 3EAXA 2CNFA 1Q6MA 3U96A 1RPMA 1T4JA 2B4UA 1C83A 1RXDA 2JJDA 4QBWA 1G1FA 1QXKA 4HJPA 2B49A 2R0BA 3V0FA 2NV5A 4S0GA 3PS5A 2GC5A 3EB1A 2GC6A 4H34A 3D1HA 4QAHA 3O5XA 1JLNA 1E8CA 2JFGA 4RDDA 2A8BA 1G1GA 2UUPA 4NX8A 2NT2A 3AWGA 1SUGA 2DXPA 1T48A 2F71A 2MBCA 1NZ7A 5EHPA 1E0DA 5A5EA 2QCTA 1M3GA 3EMUA 3MOWA 4Z6BA 1Q6NA 2UAGA 2HVLA 3D1QA 3OMHA 1W78A 1GQYA 3AWFA 5KA8A 4RHGA 1ZZWA 1FGSA 1BZJA 2XPCA 1J6UA 4OHEA 3O4TA 1I57A 4J51A 2P6XA 4IKCA 2Y96A 3ZMPA 2CNHA 1ONZA 2VEWA 1W7KA 1U24A 2F6VA 2I1YA 4H1OA 2BIJA 5KA2A 2PQ5A 1EEOA 1P15A 1YPTA 2AHSA 5A5FA 4C12A
chains in the Genus database with same CATH topology
1A5YA 4YAAA 2Y2FA 3F9BA 2FH7A 4GWFA 1ZCKA 4KYQA 4D3RA 1OETA 4ZI4A 3ZMQA 3SMEA 3QCMA 3QKQA 4HRFA 3CM3A 1G7FA 3RO1A 3V0GA 2QDCA 5MMZB 3B7OA 2HCMA 3O3LA 3F9AA 2C46A 3MMJA 3V0IA 1PXHA 4R0TA 2CM3A 1V3AA 2H4GA 5KA3A 2G6ZA 2OOQA 1WRMA 3A5JA 3QCBA 1GWZA 4B04A 2RF6A 2C7SA 2HXPA 2J17A 1Q6SA 2PI7A 5K25A 1Q6TA 3D44A 4GFVA 1YFOA 2I6IA 2I6OA 2I4EA 4JMKA 2ZN7A 2CMBA 1YTNA 5KA1A 4GS0A 1G4US 1GFYA 3N0AA 4NNDA 4AZ1A 3ZM1A 4QBEA 4QAPA 4Y14A 3S3KA 5K22A 3I36A 3ZM2A 5KA0A 1MKPA 1OEUA 2CNEA 1L8KA 5KA9A 2F6WA 1FPRA 3V0JA 1PH0A 2VEUA 4R30A 3LJ8A 1PTVA 2B4SA 1L8GA 4D3QA 4WOHA 3BRHA 1AAXA 2F6FA 4PVGA 2OC3A 3S3EA 2QDMA 3S3HA 2G59A 1JF7A 4DGXA 3QCKA 5KAAA 3A5KA 2CNIA 1PTUA 4OHHA 4NWGA 2FJNA 5AWXA 1NWEA 3RGQA 2CM2A 2QCJA 4I8NA 4GFUA 2VEVA 5HDEA 1D5RA 2QBPA 2VEXA 1PTTA 5GTJA 1T49A 2F6YA 3F41A 5K9WA 1G7GA 3QCFA 2ZMMA 1XXVA 2HC1A 2I6PA 2CMAA 1Q6JA 2CM7A 4QUMA 4GE2A 3QCIA 2B4PA 1G1HA 3I80A 3V0EA 2ESBA 4WU2A 3S3FA 3BLTA 3OLRA 1NL9A 1ZC0A 2NZ6A 4GRZA 2CM8A 2I5XA 4NWFA 3QCCA 3D42A 4RH9A 2BZLA 4D3PA 5BZZA 4WTYA 2QEPA 2P4DA 4RI5A 1YWFA 5BZXA 5LXQB 2I6JA 3SR9A 4RH5A 2HY3A 2OUDA 4QUNA 4OHLA 1QZ0A 2H02A 1PTYA 3MOZA 2WGPA 3M4UA 5IBSA 4WU3A 1I9TA 1G4WR 3EU0A 1I9SA 1XBOA 5K24A 1NWLA 1VHRA 5BX1A 2H03A 2I4GA 5IBMA 3O4UA 1OHDA 3BM8A 2PA5A 2VEYA 1OEMX 2I6MA 1C85A 2I4HA 4GRYA 4OHDA 3ZM0A 2NT7A 1ZCLA 3QCLA 3QCHA 1PYNA 1OHEA 2CNGA 4YR8B 2NTAA 3F81A 3V0DA 1R6HA 3BLUA 2CMCA 1FPZA 2CJZA 3QCDA 1WCHA 3NMEA 3GXHA 2F70A 1Q1MA 1XM2A 2B07A 2HNQA 1C87A 2I42A 3CWEA 1LQFA 2J16B 4DGPA 2NLKA 3D1OA 2M3VA 5KA7A 1XXPA 4JMJA 2QBSA 1YN9A 3QCNA 1PA9A 4JNBA 3H2XA 1LARA 2F6TA 4GE5A 3AWEA 1Q6PA 3QCGA 2PT0A 2GJTA 1PA1A 1OEOX 2GWOA 2I3UA 4R0SA 2A3KA 5KABA 5KACA 1YTSA 5KADA 2I75A 4JBCA 4KYRA 1KAKA 3ZV2A 4HJQA 3O4SA 2GP0A 2BGDA 4Y2EA 2CFVA 1YGRA 2H4VA 3S4OA 3ZM3A 1YZ4A 4MBBA 2B3OA 2HC2A 4ZN5A 5I6VA 3S4EA 3EZZA 2OZ5A 4BJOA 2Q05A 1OEVA 2QBRA 3F99A 2I3RA 1FQ1A 2YDUA 4OHIA 1NNYA 1KAVA 1YTWA 5J8RA 1J4XA 3QKPA 2H4KA 1X24A 4RI4A 5K23A 5EHRA 2F46A 2QBQA 1ECVA 3GXGA 5BUGA 1C88A 2QDPA 3I7ZA 2F6ZA 2IMGA 1C86A 2PSZA 4ZRTA 1BZHA 1NO6A 4GE6A 1XRIA 2BV5A 2HNPA 4PYHA 4ICZA 2AZRA 5KA4A 1C84A 4KI9A 2PBNA 2B4OA 3RGOA 3V0HA 2BGEA 1LYVA 1OHCA 2Q47A 1OESA 2J16A 1U25A 1WAXA 3QCEA 2FJMA 1ONYA 1EENA 4RKKA 2E0TA 3RZ2A 4NYHA 2H04A 1BZCA 4TVVA 1YGUA 2SHPA 3QCJA 4ERCA 5K9VA 5M43A 2HB1A 3D9CA 4BPCA 1U26A 3EAXA 2CNFA 1Q6MA 3U96A 1RPMA 1T4JA 2B4UA 1C83A 1RXDA 2JJDA 4QBWA 1G1FA 1QXKA 4HJPA 2B49A 2R0BA 3V0FA 2NV5A 4S0GA 3PS5A 3EB1A 4H34A 3D1HA 4QAHA 3O5XA 1JLNA 4RDDA 2A8BA 1G1GA 4NX8A 2NT2A 2F71A 1SUGA 2DXPA 1T48A 3AWGA 2MBCA 1NZ7A 5EHPA 2QCTA 1M3GA 3EMUA 3MOWA 4Z6BA 1Q6NA 2HVLA 3D1QA 3OMHA 3AWFA 5KA8A 4RHGA 1ZZWA 1BZJA 4OHEA 3O4TA 1I57A 4J51A 2P6XA 4IKCA 2Y96A 3ZMPA 2CNHA 1ONZA 2VEWA 2F6VA 1U24A 2I1YA 4H1OA 2BIJA 5KA2A 2PQ5A 1EEOA 1P15A 1YPTA 2AHSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1A5Y A;  4YAA A;  2Y2F A;  3F9B A;  2FH7 A;  4GWF A;  1ZCK A;  4KYQ A;  4D3R A;  1OET A;  4ZI4 A;  3ZMQ A;  3SME A;  3QCM A;  3QKQ A;  4HRF A;  3CM3 A;  1G7F A;  3RO1 A;  3V0G A;  2QDC A;  5MMZ B;  3B7O A;  2HCM A;  3O3L A;  3F9A A;  2C46 A;  3MMJ A;  3V0I A;  1PXH A;  4R0T A;  2CM3 A;  1V3A A;  2H4G A;  5KA3 A;  2G6Z A;  2OOQ A;  1WRM A;  3A5J A;  3QCB A;  1GWZ A;  4B04 A;  2RF6 A;  2C7S A;  2HXP A;  2J17 A;  1Q6S A;  2PI7 A;  5K25 A;  1Q6T A;  3D44 A;  4GFV A;  1YFO A;  2I6I A;  2I6O A;  2I4E A;  4JMK A;  2ZN7 A;  2CMB A;  1YTN A;  5KA1 A;  4GS0 A;  1G4U S;  1GFY A;  3N0A A;  4NND A;  4AZ1 A;  3ZM1 A;  4QBE A;  4QAP A;  4Y14 A;  3S3K A;  5K22 A;  3I36 A;  3ZM2 A;  5KA0 A;  1MKP A;  1OEU A;  2CNE A;  1L8K A;  5KA9 A;  2F6W A;  1FPR A;  3V0J A;  1PH0 A;  2VEU A;  4R30 A;  3LJ8 A;  1PTV A;  2B4S A;  1L8G A;  4D3Q A;  4WOH A;  3BRH A;  1AAX A;  2F6F A;  4PVG A;  2OC3 A;  3S3E A;  2QDM A;  3S3H A;  2G59 A;  1JF7 A;  4DGX A;  3QCK A;  5KAA A;  3A5K A;  2CNI A;  1PTU A;  4OHH A;  4NWG A;  2FJN A;  5AWX A;  1NWE A;  3RGQ A;  2CM2 A;  2QCJ A;  4I8N A;  4GFU A;  2VEV A;  5HDE A;  1D5R A;  2QBP A;  2VEX A;  1PTT A;  5GTJ A;  1T49 A;  2F6Y A;  3F41 A;  5K9W A;  1G7G A;  3QCF A;  2ZMM A;  1XXV A;  2HC1 A;  2I6P A;  2CMA A;  1Q6J A;  2CM7 A;  4QUM A;  4GE2 A;  3QCI A;  2B4P A;  1G1H A;  3I80 A;  3V0E A;  2ESB A;  4WU2 A;  3S3F A;  3BLT A;  3OLR A;  1NL9 A;  1ZC0 A;  2NZ6 A;  4GRZ A;  2CM8 A;  2I5X A;  4NWF A;  3QCC A;  3D42 A;  4RH9 A;  2BZL A;  4D3P A;  5BZZ A;  4WTY A;  2QEP A;  2P4D A;  4RI5 A;  1YWF A;  5BZX A;  5LXQ B;  2I6J A;  3SR9 A;  4RH5 A;  2HY3 A;  2OUD A;  4QUN A;  4OHL A;  1QZ0 A;  2H02 A;  1PTY A;  3MOZ A;  2WGP A;  3M4U A;  5IBS A;  4WU3 A;  1I9T A;  1G4W R;  3EU0 A;  1I9S A;  1XBO A;  5K24 A;  1NWL A;  1VHR A;  5BX1 A;  2H03 A;  2I4G A;  5IBM A;  3O4U A;  1OHD A;  3BM8 A;  2PA5 A;  2VEY A;  1OEM X;  2I6M A;  1C85 A;  2I4H A;  4GRY A;  4OHD A;  3ZM0 A;  2NT7 A;  1ZCL A;  3QCL A;  3QCH A;  1PYN A;  1OHE A;  2CNG A;  4YR8 B;  2NTA A;  3F81 A;  3V0D A;  1R6H A;  3BLU A;  2CMC A;  1FPZ A;  2CJZ A;  3QCD A;  1WCH A;  3NME A;  3GXH A;  2F70 A;  1Q1M A;  1XM2 A;  2B07 A;  2HNQ A;  1C87 A;  2I42 A;  3CWE A;  1LQF A;  2J16 B;  4DGP A;  2NLK A;  3D1O A;  2M3V A;  5KA7 A;  1XXP A;  4JMJ A;  2QBS A;  1YN9 A;  3QCN A;  1PA9 A;  4JNB A;  3H2X A;  1LAR A;  2F6T A;  4GE5 A;  3AWE A;  1Q6P A;  3QCG A;  2PT0 A;  2GJT A;  1PA1 A;  1OEO X;  2GWO A;  2I3U A;  4R0S A;  2A3K A;  5KAB A;  5KAC A;  1YTS A;  5KAD A;  2I75 A;  4JBC A;  4KYR A;  1KAK A;  3ZV2 A;  4HJQ A;  3O4S A;  2GP0 A;  2BGD A;  4Y2E A;  2CFV A;  1YGR A;  2H4V A;  3S4O A;  3ZM3 A;  1YZ4 A;  4MBB A;  2B3O A;  2HC2 A;  4ZN5 A;  5I6V A;  3S4E A;  3EZZ A;  2OZ5 A;  4BJO A;  2Q05 A;  1OEV A;  2QBR A;  3F99 A;  2I3R A;  1FQ1 A;  2YDU A;  4OHI A;  1NNY A;  1KAV A;  1YTW A;  5J8R A;  1J4X A;  3QKP A;  2H4K A;  1X24 A;  4RI4 A;  5K23 A;  5EHR A;  2F46 A;  2QBQ A;  1ECV A;  3GXG A;  5BUG A;  1C88 A;  2QDP A;  3I7Z A;  2F6Z A;  2IMG A;  1C86 A;  2PSZ A;  4ZRT A;  1BZH A;  1NO6 A;  4GE6 A;  1XRI A;  2BV5 A;  2HNP A;  4PYH A;  4ICZ A;  2AZR A;  5KA4 A;  1C84 A;  4KI9 A;  2PBN A;  2B4O A;  3RGO A;  3V0H A;  2BGE A;  1LYV A;  1OHC A;  2Q47 A;  1OES A;  2J16 A;  1U25 A;  1WAX A;  3QCE A;  2FJM A;  1ONY A;  1EEN A;  4RKK A;  2E0T A;  3RZ2 A;  4NYH A;  2H04 A;  1BZC A;  4TVV A;  1YGU A;  2SHP A;  3QCJ A;  4ERC A;  5K9V A;  5M43 A;  2HB1 A;  3D9C A;  4BPC A;  1U26 A;  3EAX A;  2CNF A;  1Q6M A;  3U96 A;  1RPM A;  1T4J A;  2B4U A;  1C83 A;  1RXD A;  2JJD A;  4QBW A;  1G1F A;  1QXK A;  4HJP A;  2B49 A;  2R0B A;  3V0F A;  2NV5 A;  4S0G A;  3PS5 A;  3EB1 A;  4H34 A;  3D1H A;  4QAH A;  3O5X A;  1JLN A;  4RDD A;  2A8B A;  1G1G A;  4NX8 A;  2NT2 A;  2F71 A;  1SUG A;  2DXP A;  1T48 A;  3AWG A;  2MBC A;  1NZ7 A;  5EHP A;  2QCT A;  1M3G A;  3EMU A;  3MOW A;  4Z6B A;  1Q6N A;  2HVL A;  3D1Q A;  3OMH A;  3AWF A;  5KA8 A;  4RHG A;  1ZZW A;  1BZJ A;  4OHE A;  3O4T A;  1I57 A;  4J51 A;  2P6X A;  4IKC A;  2Y96 A;  3ZMP A;  2CNH A;  1ONZ A;  2VEW A;  2F6V A;  1U24 A;  2I1Y A;  4H1O A;  2BIJ A;  5KA2 A;  2PQ5 A;  1EEO A;  1P15 A;  1YPT A;  2AHS A; 
#chains in the Genus database with same CATH topology
 1A5Y A;  2GCB A;  4YAA A;  2Y2F A;  3F9B A;  2FH7 A;  4GWF A;  1ZCK A;  4KYQ A;  4D3R A;  1OET A;  4ZI4 A;  3ZMQ A;  4CVM A;  3SME A;  3QCM A;  3QKQ A;  4HRF A;  3CM3 A;  1G7F A;  3RO1 A;  3V0G A;  2QDC A;  5MMZ B;  3B7O A;  2HCM A;  3O3L A;  3F9A A;  2C46 A;  3MMJ A;  3V0I A;  3N2A A;  1PXH A;  2GCA A;  4R0T A;  2CM3 A;  2VTD A;  1O5Z A;  1V3A A;  2H4G A;  5KA3 A;  3QCZ A;  2G6Z A;  2OOQ A;  1WRM A;  3A5J A;  3QCB A;  1GWZ A;  4B04 A;  2WJP A;  2RF6 A;  2C7S A;  2HXP A;  2J17 A;  1Q6S A;  2PI7 A;  5K25 A;  2AM2 A;  1Q6T A;  3D44 A;  4GFV A;  1YFO A;  2I6I A;  3NRS A;  2I6O A;  2Y67 A;  2I4E A;  4JMK A;  2ZN7 A;  2CMB A;  1YTN A;  4ZIY A;  5KA1 A;  4GS0 A;  1G4U S;  1GFY A;  3N0A A;  4NND A;  4AZ1 A;  3ZM1 A;  4QBE A;  4QAP A;  4Y14 A;  3S3K A;  5K22 A;  3I36 A;  3ZM2 A;  5KA0 A;  1MKP A;  1OEU A;  2CNE A;  1L8K A;  5KA9 A;  1GG4 A;  2F00 A;  2F6W A;  1FPR A;  3V0J A;  1PH0 A;  2VEU A;  4R30 A;  3ZM5 A;  3LJ8 A;  1PTV A;  1GQQ A;  2B4S A;  1L8G A;  4D3Q A;  4HV4 A;  4WOH A;  4CVK A;  3BRH A;  1P3D A;  1AAX A;  2F6F A;  1JBV A;  4PVG A;  2OC3 A;  3S3E A;  2QDM A;  3S3H A;  2G59 A;  1JF7 A;  4DGX A;  3QCK A;  5KAA A;  3A5K A;  2CNI A;  2UUO A;  1PTU A;  1P31 A;  4OHH A;  4NWG A;  2FJN A;  5AWX A;  1NWE A;  4UAG A;  2CM2 A;  3RGQ A;  2QCJ A;  4I8N A;  4GFU A;  2VEV A;  5HDE A;  1D5R A;  2QBP A;  2VEX A;  1PTT A;  5GTJ A;  1T49 A;  2F6Y A;  3F41 A;  5K9W A;  1G7G A;  3QCF A;  3MVN A;  2ZMM A;  1XXV A;  2HC1 A;  2I6P A;  2CMA A;  1Q6J A;  2CM7 A;  4QUM A;  3LK7 A;  4GE2 A;  3HN7 A;  3QCI A;  2B4P A;  1G1H A;  3I80 A;  2VOS A;  3V0E A;  2ESB A;  4WU2 A;  3S3F A;  3BLT A;  3OLR A;  1NL9 A;  1ZC0 A;  2NZ6 A;  4GRZ A;  2CM8 A;  2I5X A;  4NWF A;  3QCC A;  4CVL A;  3D42 A;  4RH9 A;  2BZL A;  4D3P A;  5BZZ A;  4WTY A;  2QEP A;  2P4D A;  4RI5 A;  1YWF A;  5BZX A;  5LXQ B;  2I6J A;  3SR9 A;  4RH5 A;  2HY3 A;  2OUD A;  2WTZ A;  4QUN A;  2JFF A;  4OHL A;  2VOR A;  1QZ0 A;  2H02 A;  1PTY A;  4QDI A;  3MOZ A;  2WGP A;  3M4U A;  5IBS A;  4WU3 A;  1EEH A;  1I9T A;  1G4W R;  3EU0 A;  1I9S A;  1XBO A;  5K24 A;  1NWL A;  1VHR A;  5BX1 A;  2H03 A;  2I4G A;  3UAG A;  5IBM A;  3O4U A;  1OHD A;  3BM8 A;  2PA5 A;  2VEY A;  4C13 A;  1OEM X;  2I6M A;  1C85 A;  2I4H A;  4GRY A;  4OHD A;  3ZM0 A;  2NT7 A;  4QF5 A;  3ZM6 A;  1ZCL A;  3QCL A;  3QCH A;  1PYN A;  1UAG A;  1OHE A;  2CNG A;  4YR8 B;  2NTA A;  3F81 A;  3V0D A;  1R6H A;  3BLU A;  2CMC A;  1FPZ A;  2CJZ A;  3QCD A;  2JFH A;  1WCH A;  3NME A;  3GXH A;  2F70 A;  1Q1M A;  1XM2 A;  2B07 A;  2HNQ A;  1C87 A;  2I42 A;  3CWE A;  1LQF A;  2J16 B;  4DGP A;  2NLK A;  3D1O A;  2M3V A;  5KA7 A;  1XXP A;  4JMJ A;  2QBS A;  1YN9 A;  3QCN A;  1PA9 A;  4JNB A;  1LAR A;  3H2X A;  2F6T A;  4BUB A;  4GE5 A;  3AWE A;  1Q6P A;  3QCG A;  2PT0 A;  2GJT A;  1PA1 A;  1OEO X;  2GWO A;  2I3U A;  4R0S A;  2A3K A;  5KAB A;  5KAC A;  1YTS A;  5KAD A;  2I75 A;  4JBC A;  4KYR A;  1KAK A;  3ZV2 A;  4HJQ A;  3O4S A;  2GP0 A;  2BGD A;  4Y2E A;  2CFV A;  4BUC A;  1JBW A;  1YGR A;  2H4V A;  3S4O A;  3ZM3 A;  1YZ4 A;  4MBB A;  2B3O A;  2HC2 A;  4ZN5 A;  5I6V A;  2AM1 A;  3S4E A;  3EZZ A;  2OZ5 A;  3PYZ A;  2Q05 A;  4BJO A;  1OEV A;  2QBR A;  3F99 A;  2I3R A;  1FQ1 A;  2YDU A;  2X5O A;  4OHI A;  1NNY A;  1KAV A;  1YTW A;  5J8R A;  1J4X A;  3QKP A;  2H4K A;  1X24 A;  4RI4 A;  3ZL8 A;  5K23 A;  5EHR A;  2F46 A;  2QBQ A;  1ECV A;  3GXG A;  5BUG A;  1C88 A;  2QDP A;  2Y1O A;  3I7Z A;  2F6Z A;  2IMG A;  1C86 A;  2Y66 A;  2PSZ A;  4ZRT A;  1BZH A;  1NO6 A;  4GE6 A;  1XRI A;  2VTE A;  2BV5 A;  2HNP A;  4PYH A;  4ICZ A;  2AZR A;  2XJA A;  1C84 A;  5KA4 A;  4KI9 A;  2PBN A;  2B4O A;  3RGO A;  3V0H A;  2BGE A;  1LYV A;  1OHC A;  2Q47 A;  1OES A;  2J16 A;  1U25 A;  1WAX A;  3QCE A;  2FJM A;  1ONY A;  1EEN A;  4RKK A;  2E0T A;  3RZ2 A;  4NYH A;  2H04 A;  1BZC A;  4TVV A;  1YGU A;  2SHP A;  2Y68 A;  3QCJ A;  4ERC A;  5K9V A;  5M43 A;  2HB1 A;  3D9C A;  4BPC A;  1U26 A;  3EAX A;  2CNF A;  1Q6M A;  3U96 A;  1RPM A;  1T4J A;  2B4U A;  1C83 A;  1RXD A;  2JJD A;  4QBW A;  1G1F A;  1QXK A;  4HJP A;  2B49 A;  2R0B A;  3V0F A;  2NV5 A;  4S0G A;  3PS5 A;  2GC5 A;  3EB1 A;  2GC6 A;  4H34 A;  3D1H A;  4QAH A;  3O5X A;  1JLN A;  1E8C A;  2JFG A;  4RDD A;  2A8B A;  1G1G A;  2UUP A;  4NX8 A;  2NT2 A;  3AWG A;  1SUG A;  2DXP A;  1T48 A;  2F71 A;  2MBC A;  1NZ7 A;  5EHP A;  1E0D A;  5A5E A;  2QCT A;  1M3G A;  3EMU A;  3MOW A;  4Z6B A;  1Q6N A;  2UAG A;  2HVL A;  3D1Q A;  3OMH A;  1W78 A;  1GQY A;  3AWF A;  5KA8 A;  4RHG A;  1ZZW A;  1FGS A;  1BZJ A;  2XPC A;  1J6U A;  4OHE A;  3O4T A;  1I57 A;  4J51 A;  2P6X A;  4IKC A;  2Y96 A;  3ZMP A;  2CNH A;  1ONZ A;  2VEW A;  1W7K A;  1U24 A;  2F6V A;  2I1Y A;  4H1O A;  2BIJ A;  5KA2 A;  2PQ5 A;  1EEO A;  1P15 A;  1YPT A;  2AHS A;  5A5F A;  4C12 A; 
#chains in the Genus database with same CATH homology
 1A5Y A;  4YAA A;  2Y2F A;  3F9B A;  2FH7 A;  4GWF A;  1ZCK A;  4KYQ A;  4D3R A;  1OET A;  4ZI4 A;  3ZMQ A;  3SME A;  3QCM A;  3QKQ A;  4HRF A;  3CM3 A;  1G7F A;  3RO1 A;  3V0G A;  2QDC A;  5MMZ B;  3B7O A;  2HCM A;  3O3L A;  3F9A A;  2C46 A;  3MMJ A;  3V0I A;  1PXH A;  4R0T A;  2CM3 A;  1V3A A;  2H4G A;  5KA3 A;  2G6Z A;  2OOQ A;  1WRM A;  3A5J A;  3QCB A;  1GWZ A;  4B04 A;  2RF6 A;  2C7S A;  2HXP A;  2J17 A;  1Q6S A;  2PI7 A;  5K25 A;  1Q6T A;  3D44 A;  4GFV A;  1YFO A;  2I6I A;  2I6O A;  2I4E A;  4JMK A;  2ZN7 A;  2CMB A;  1YTN A;  5KA1 A;  4GS0 A;  1G4U S;  1GFY A;  3N0A A;  4NND A;  4AZ1 A;  3ZM1 A;  4QBE A;  4QAP A;  4Y14 A;  3S3K A;  5K22 A;  3I36 A;  3ZM2 A;  5KA0 A;  1MKP A;  1OEU A;  2CNE A;  1L8K A;  5KA9 A;  2F6W A;  1FPR A;  3V0J A;  1PH0 A;  2VEU A;  4R30 A;  3LJ8 A;  1PTV A;  2B4S A;  1L8G A;  4D3Q A;  4WOH A;  3BRH A;  1AAX A;  2F6F A;  4PVG A;  2OC3 A;  3S3E A;  2QDM A;  3S3H A;  2G59 A;  1JF7 A;  4DGX A;  3QCK A;  5KAA A;  3A5K A;  2CNI A;  1PTU A;  4OHH A;  4NWG A;  2FJN A;  5AWX A;  1NWE A;  3RGQ A;  2CM2 A;  2QCJ A;  4I8N A;  4GFU A;  2VEV A;  5HDE A;  1D5R A;  2QBP A;  2VEX A;  1PTT A;  5GTJ A;  1T49 A;  2F6Y A;  3F41 A;  5K9W A;  1G7G A;  3QCF A;  2ZMM A;  1XXV A;  2HC1 A;  2I6P A;  2CMA A;  1Q6J A;  2CM7 A;  4QUM A;  4GE2 A;  3QCI A;  2B4P A;  1G1H A;  3I80 A;  3V0E A;  2ESB A;  4WU2 A;  3S3F A;  3BLT A;  3OLR A;  1NL9 A;  1ZC0 A;  2NZ6 A;  4GRZ A;  2CM8 A;  2I5X A;  4NWF A;  3QCC A;  3D42 A;  4RH9 A;  2BZL A;  4D3P A;  5BZZ A;  4WTY A;  2QEP A;  2P4D A;  4RI5 A;  1YWF A;  5BZX A;  5LXQ B;  2I6J A;  3SR9 A;  4RH5 A;  2HY3 A;  2OUD A;  4QUN A;  4OHL A;  1QZ0 A;  2H02 A;  1PTY A;  3MOZ A;  2WGP A;  3M4U A;  5IBS A;  4WU3 A;  1I9T A;  1G4W R;  3EU0 A;  1I9S A;  1XBO A;  5K24 A;  1NWL A;  1VHR A;  5BX1 A;  2H03 A;  2I4G A;  5IBM A;  3O4U A;  1OHD A;  3BM8 A;  2PA5 A;  2VEY A;  1OEM X;  2I6M A;  1C85 A;  2I4H A;  4GRY A;  4OHD A;  3ZM0 A;  2NT7 A;  1ZCL A;  3QCL A;  3QCH A;  1PYN A;  1OHE A;  2CNG A;  4YR8 B;  2NTA A;  3F81 A;  3V0D A;  1R6H A;  3BLU A;  2CMC A;  1FPZ A;  2CJZ A;  3QCD A;  1WCH A;  3NME A;  3GXH A;  2F70 A;  1Q1M A;  1XM2 A;  2B07 A;  2HNQ A;  1C87 A;  2I42 A;  3CWE A;  1LQF A;  2J16 B;  4DGP A;  2NLK A;  3D1O A;  2M3V A;  5KA7 A;  1XXP A;  4JMJ A;  2QBS A;  1YN9 A;  3QCN A;  1PA9 A;  4JNB A;  3H2X A;  1LAR A;  2F6T A;  4GE5 A;  3AWE A;  1Q6P A;  3QCG A;  2PT0 A;  2GJT A;  1PA1 A;  1OEO X;  2GWO A;  2I3U A;  4R0S A;  2A3K A;  5KAB A;  5KAC A;  1YTS A;  5KAD A;  2I75 A;  4JBC A;  4KYR A;  1KAK A;  3ZV2 A;  4HJQ A;  3O4S A;  2GP0 A;  2BGD A;  4Y2E A;  2CFV A;  1YGR A;  2H4V A;  3S4O A;  3ZM3 A;  1YZ4 A;  4MBB A;  2B3O A;  2HC2 A;  4ZN5 A;  5I6V A;  3S4E A;  3EZZ A;  2OZ5 A;  4BJO A;  2Q05 A;  1OEV A;  2QBR A;  3F99 A;  2I3R A;  1FQ1 A;  2YDU A;  4OHI A;  1NNY A;  1KAV A;  1YTW A;  5J8R A;  1J4X A;  3QKP A;  2H4K A;  1X24 A;  4RI4 A;  5K23 A;  5EHR A;  2F46 A;  2QBQ A;  1ECV A;  3GXG A;  5BUG A;  1C88 A;  2QDP A;  3I7Z A;  2F6Z A;  2IMG A;  1C86 A;  2PSZ A;  4ZRT A;  1BZH A;  1NO6 A;  4GE6 A;  1XRI A;  2BV5 A;  2HNP A;  4PYH A;  4ICZ A;  2AZR A;  5KA4 A;  1C84 A;  4KI9 A;  2PBN A;  2B4O A;  3RGO A;  3V0H A;  2BGE A;  1LYV A;  1OHC A;  2Q47 A;  1OES A;  2J16 A;  1U25 A;  1WAX A;  3QCE A;  2FJM A;  1ONY A;  1EEN A;  4RKK A;  2E0T A;  3RZ2 A;  4NYH A;  2H04 A;  1BZC A;  4TVV A;  1YGU A;  2SHP A;  3QCJ A;  4ERC A;  5K9V A;  5M43 A;  2HB1 A;  3D9C A;  4BPC A;  1U26 A;  3EAX A;  2CNF A;  1Q6M A;  3U96 A;  1RPM A;  1T4J A;  2B4U A;  1C83 A;  1RXD A;  2JJD A;  4QBW A;  1G1F A;  1QXK A;  4HJP A;  2B49 A;  2R0B A;  3V0F A;  2NV5 A;  4S0G A;  3PS5 A;  3EB1 A;  4H34 A;  3D1H A;  4QAH A;  3O5X A;  1JLN A;  4RDD A;  2A8B A;  1G1G A;  4NX8 A;  2NT2 A;  2F71 A;  1SUG A;  2DXP A;  1T48 A;  3AWG A;  2MBC A;  1NZ7 A;  5EHP A;  2QCT A;  1M3G A;  3EMU A;  3MOW A;  4Z6B A;  1Q6N A;  2HVL A;  3D1Q A;  3OMH A;  3AWF A;  5KA8 A;  4RHG A;  1ZZW A;  1BZJ A;  4OHE A;  3O4T A;  1I57 A;  4J51 A;  2P6X A;  4IKC A;  2Y96 A;  3ZMP A;  2CNH A;  1ONZ A;  2VEW A;  2F6V A;  1U24 A;  2I1Y A;  4H1O A;  2BIJ A;  5KA2 A;  2PQ5 A;  1EEO A;  1P15 A;  1YPT A;  2AHS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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