1O0TA

Crystal structure of a cold adapted alkaline protease from pseudomonas tac ii 18, co-crystallized with 5 mm edta (5 days)
Total Genus 144
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
144
sequence length
461
structure length
455
Chain Sequence
GTSSAFTQIDNFSHFYDRGDHLVNGKPSFTVDQVADQLTRSGASWHDLNNDGVINLTYTFLTAPPVGYASRGLGTFSQFSALQKEQAKLSLESWADVAKVTFTEGPAARGDDGHMTFANFSASNGGAAFAYLPNSSRKGESWYLINKDYQVNKTPGEGNYGRQTLTHEIGHTLGLSHPGDNPTYRDAVYAEDTRAYSVMSYWSEKNTGQVFTKTGEGAYASAPLLDDIAAVQKLYGANLETRADDTVYGFNSTADRDFYSATSSTDKLIFSVWDGGGNDTLDFSGFSQNQKINLTAGSFSDVGGMTGNVSIAQGVTIENAIGGSGNDLLIGNDAANVLKGGAGNDIIYGGGGADVLWGGTGSDTFVFGAVSDSTPKAADIIKDFQSGFDKIDLTAITKLGGLNFVDAFTGHAGDAIVSYHQASNAGSLQVDFSGQGVADFLVTTVGQVATYDIVA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Probing the role of divalent metal ions in a bacterial psychrophilic metalloprotease: binding studies of an enzyme in the crystalline state by x-ray crystallography.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords serralysin
total genus 144
structure length 455
sequence length 461
ec nomenclature ec 3.4.24.40: Serralysin.
pdb deposition date 2003-02-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00353 HemolysinCabind RTX calcium-binding nonapeptide repeat (4 copies)
A PF08548 Peptidase_M10_C Peptidase M10 serralysin C terminal
A PF13583 Reprolysin_4 Metallo-peptidase family M12B Reprolysin-like
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.150.10.10 Mainly Beta 2 Solenoid Alkaline Protease, subunit P, domain 1 Serralysin-like metalloprotease, C-terminal 1o0tA01
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 1o0tA02
1G4KA 2W13A 3F18A 2W12A 1EUBA 4GF1A 2QPJA 1QUAA 1JAPA 4XM6A 2W14A 4HMAA 3KHIA 3F16A 1J7NA 4WF6A 1OS2A 5I12A 1XFYA 3LJGA 3HYGA 4XM7A 4PKWA 2Z8ZA 5BOTA 2X3AA 2ZJ6A 1ZS0A 5I43A 3AIGA 4DF9A 1R1IA 1USNA 3HBUP 3WP8A 1A85A 1EB6A 1BQOA 3LA9A 2CLTA 2Z2DA 1BUVM 3A70A 5D7WA 4H1QA 1YCMA 2OVXA 2ERPA 5JMYA 1UTTA 1Z3JA 5L79A 2MZIA 1WNIA 2OW0A 3U1RA 3LUMA 4H49A 2PJTA 3EDIA 1QJJA 3ZXHA 5I3MA 1L6JA 1QIAA 5D2BA 1QICA 5I4OA 4DV8A 2YO1A 2MLSA 1R55A 1ND1A 1PWWA 2JT5A 4JIJA 1K7QA 2D1OA 1GE6A 1ZXVA 4PKRA 1PWPA 2KRJA 2W0DA 3MA2A 4A3WA 3DPFA 1I1IP 4R3VA 2XS4A 2J0TA 4GR0A 4WKEA 2POJA 2OW9A 4FXYP 1KAPP 1C3IA 1JANA 3B92A 3F15A 3WV2A 3DPEA 4Q1LA 4AIGA 1MMQA 3SHIA 2RJPA 1IAEA 1G9KA 3LEAA 1JKYA 1OM7A 5CZMA 1RMZA 3I7GA 1BZSA 3P24A 2E3XA 2JSDA 1XFXA 4H82A 2OXZA 3DWBA 3AYKA 1P9HA 2OY4A 3ZVSA 3N2VA 4XM8A 1R1HA 1BKCE 3CKIA 1XURA 3DNGA 1K7GA 1FBLA 4AXQA 5CXAA 3HY7A 1ATLA 1C8TA 4FXQA 2O3EA 1SMPA 1C7KA 1QIBA 2CKIA 4ON1A 1IAAA 3F1AA 3E8RA 1JIWP 3LIRA 3EDZA 2I47A 2DW1A 1QJIA 5H8XA 4EFSA 3VI1A 5CUHA 3NX7A 1MMBA 1KUKA 4JP4A 2XQHA 2RJQA 2YIGA 2JIHA 4AYKA 3LMCA 4JPAA 4XCTA 2MZEA 4IUWA 1R1JA 1OM8A 2OW2A 4L6TA 2K2GA 2EROA 3GBOA 3B2ZA 1PWQA 3WV1A 1MMPA 1ROSA 1CAQA 2DDYA 1HFCA 5LABA 3UVCA 1CIZA 3EHXA 2DDFA 5D1SA 2OY2A 3HDAP 1GXDA 1OM6A 3EDHA 1BIWA 4WZVA 2ZVDA 4IJOA 3TS4A 1S4BP 1CK7A 2QUBA 4QKZA 5B5PA 4PKQA 1MMRA 2OW1A 1MNCA 4ZR5A 4FU4A 5CXLA 1ZP5A 1I76A 3KWVC 3F19A 3F17A 1I73A 1BKCA 5D1UA 1HY7A 2W15A 1CGLA 1BUDA 1YQYA 2V4BA 4H84A 1JJ9A 1UTZA 1YOUA 3LJZA 5D1TA 1CXVA 456CA 3HBVP 2HU6A 2X3BA 5B5OA 1OS9A 1HOVA 3AYUA 3ELMA 1R54A 3K7NA 3N2UA 3Q2GA 3ZUKA 3L0TA 1O0TA 1JAQA 1Y0VA 1ASTA 3RTTA 1GKCA 2AYKA 2YB9A 1XFVA 1B8YA 1ZVXA 1JH1A 2D1NA 4GQLA 2N8RA 2Y6DA 1ZXCA 2Z8XA 3KMCA 3I7IA 3VTGA 4PKUA 1Y93A 1JIZA 4PKTA 1Y8JA 1Q3AA 1KBCA 3KEKA 2E2DA 5BOYA 4XBHA 3LAAA 1D7XA 2MLRA 2DW0A 3LK8A 4FVLA 4IN9A 1JK3A 1FM1A 4H2EA 1A86A 1GO8P 1D8MA 3LE9A 1HTDA 2ERQA 2ZJ7A 4H30A 1XUCA 3WV3A 3S6LA 2K9CA 3LILA 3ULTA 1DMTA 1AYKA 2FV5A 2SRTA 2OXUA 2JNPA 1UMSA 1KUFA 3HB2P 2A8HA 3RTSA 830CA 1D5JA 3OHLA 3EDGA 5D3CA 4L19A 1UEAA 1XFUA 1KUHA 3LQ0A 3TSKA 1DTHA 1UMTA 1GE7A 1B3DA 1D8FA 4L63A 1JAOA 1G05A 1SRPA 3G42A 4DPEA 2YO0A 1XUDA 3OHOA 2JT6A 4H3XA 4DD8A 3P1VA 3TVCA 3A6ZA 1XFWA 3O64A 4ILWD 4PKSA 4GWMA 1YP1A 4PKVA 3LKAA 2AIGP 5CVWA 1IACA 1AF0A 3KMEA 4AUOA 4JQGA 1BSWA 3USNA 1BM6A 1G49A 5I0LA 2AGMA 1EAKA 1OMJA 2O36A 4A7BA 2DW2A 3KEJA 4WKIA 1CGFA 1SU3A 4I35A 1ZTQA 3HDBA 2X7MA 1FLSA 1IADA 4G0DA 2FV9A 3LJTA 1XFZA 4J4MA 2L0RA 3K7LA 1GKDA 2Y6CA 3O2XA 1G12A 2USNA 2XS3A 3BA0A 2OZRA 1CGEA 3KECA 1PWVA 1K7IA 1CQRA 3HY9A 3B8ZA 2WO8A 2ML2A 4GWNA 2QUAA 5BPAA 3Q2HA 2WOAA 4G9LA 3NTNA 1SLMA 3KRYA 1GE5A 4HX3A 3DL1A 1IABA 1PWUA 1O0QA 2OVZA 1HFSA 2WO9A 3LQBA 4GR8A 2X3CA 3TT4A 3LGPA 3LUNA 3V96B 1RM8A 1H71P 3EHYA 1OO9A 966CA 4GUYA 4WK7A 1KUGA 3LIKA 4H76A 4CTHA 2MZHA 1SATA 3L0VA 3EWJA 2J83A 5I2ZA 1BKCI 2TCLA 1KUIA 4GR3A 1SLNA 4JA1A 1BQQM 3G5CA 5L7FA 3DSLA 1GO7P 2OI0A 1HV5A 4I03A 1IAGA 1AKLA 2OXWA
chains in the Genus database with same CATH superfamily
1G4KA 2W13A 3F18A 2W12A 1EUBA 4GF1A 2QPJA 1QUAA 1JAPA 4XM6A 2W14A 4HMAA 3KHIA 3F16A 1J7NA 4WF6A 1OS2A 5I12A 1XFYA 3LJGA 3HYGA 4XM7A 4PKWA 2Z8ZA 5BOTA 2X3AA 2ZJ6A 1ZS0A 5I43A 3AIGA 4DF9A 1R1IA 1USNA 3HBUP 3WP8A 1A85A 1EB6A 1BQOA 3LA9A 2CLTA 2Z2DA 1BUVM 3A70A 5D7WA 4H1QA 1YCMA 2OVXA 2ERPA 5JMYA 1UTTA 1Z3JA 5L79A 1TVIA 2MZIA 1WNIA 1XM5A 2OW0A 3U1RA 3LUMA 4H49A 2PJTA 3EDIA 1QJJA 3ZXHA 5I3MA 1L6JA 1QIAA 5D2BA 1QICA 5I4OA 4DV8A 2YO1A 2MLSA 1R55A 1ND1A 1PWWA 2JT5A 4JIJA 1K7QA 2D1OA 1GE6A 1ZXVA 4PKRA 1PWPA 2KRJA 2W0DA 3MA2A 4A3WA 3DPFA 1I1IP 4R3VA 2XS4A 2J0TA 4GR0A 4WKEA 2POJA 2OW9A 4FXYP 1KAPP 1C3IA 1JANA 3B92A 3F15A 3WV2A 3DPEA 4Q1LA 4AIGA 1MMQA 3SHIA 2RJPA 1IAEA 1G9KA 3LEAA 1JKYA 1OM7A 5CZMA 1RMZA 3I7GA 1BZSA 3P24A 2E3XA 2JSDA 4L7AA 1XFXA 4H82A 2OXZA 3DWBA 3AYKA 1P9HA 2OY4A 3ZVSA 3N2VA 4XM8A 1R1HA 1BKCE 3CKIA 1XURA 3DNGA 1K7GA 1FBLA 4AXQA 5CXAA 3HY7A 1ATLA 1C8TA 4FXQA 2O3EA 1SMPA 1C7KA 1QIBA 2CKIA 4ON1A 1IAAA 3F1AA 3E8RA 1JIWP 3LIRA 3EDZA 2I47A 2DW1A 1QJIA 5H8XA 4EFSA 3VI1A 5CUHA 3NX7A 1MMBA 1KUKA 4JP4A 2XQHA 2RJQA 2YIGA 2JIHA 4AYKA 3LMCA 4JPAA 4XCTA 2MZEA 4IUWA 1R1JA 1OM8A 2OW2A 4L6TA 2K2GA 2EROA 3GBOA 3B2ZA 1PWQA 3WV1A 1MMPA 1ROSA 1CAQA 2DDYA 1HFCA 5LABA 3UVCA 1CIZA 3EHXA 2DDFA 5D1SA 2OY2A 3HDAP 1GXDA 1OM6A 3EDHA 1BIWA 4WZVA 2ZVDA 4IJOA 3TS4A 1S4BP 1CK7A 2QUBA 4QKZA 5B5PA 4PKQA 1MMRA 2OW1A 1MNCA 4ZR5A 4FU4A 5CXLA 1ZP5A 1I76A 3KWVC 3F19A 3F17A 1I73A 1BKCA 5D1UA 1HY7A 2W15A 1CGLA 1BUDA 1YQYA 2V4BA 4H84A 1JJ9A 1UTZA 1YOUA 3LJZA 5D1TA 1CXVA 456CA 3HBVP 2HU6A 2X3BA 5B5OA 1OS9A 1HOVA 3AYUA 3ELMA 1R54A 3K7NA 2YUFA 3N2UA 3Q2GA 3ZUKA 3L0TA 1O0TA 1JAQA 1Y0VA 1ASTA 3RTTA 1GKCA 2AYKA 2YB9A 1XFVA 1B8YA 1ZVXA 1JH1A 2D1NA 4GQLA 2N8RA 2Y6DA 3DTEA 1ZXCA 2Z8XA 3KMCA 3I7IA 3VTGA 4PKUA 1Y93A 1JIZA 4PKTA 1Y8JA 1Q3AA 1KBCA 3KEKA 2E2DA 5BOYA 4XBHA 3LAAA 1D7XA 2MLRA 2DW0A 1OZ9A 3LK8A 4FVLA 4IN9A 1JK3A 1FM1A 4H2EA 1A86A 1GO8P 1D8MA 3LE9A 1HTDA 2ERQA 2ZJ7A 4H30A 1XUCA 3WV3A 3S6LA 2K9CA 3LILA 3ULTA 1DMTA 1AYKA 2FV5A 2SRTA 4DT5A 2OXUA 2JNPA 1UMSA 1KUFA 3HB2P 2A8HA 3RTSA 830CA 1D5JA 3OHLA 3EDGA 5D3CA 4L19A 1UEAA 1XFUA 1KUHA 3LQ0A 3TSKA 1DTHA 1UMTA 1GE7A 1B3DA 1D8FA 4L63A 1JAOA 1G05A 1SRPA 3G42A 4DPEA 2YO0A 1XUDA 3OHOA 2JT6A 4H3XA 4DD8A 3P1VA 3TVCA 3A6ZA 1XFWA 3O64A 3DTKA 4ILWD 4PKSA 4GWMA 1YP1A 4PKVA 3LKAA 2AIGP 5CVWA 1IACA 1AF0A 3KMEA 4AUOA 4JQGA 1BSWA 3USNA 1BM6A 1G49A 5I0LA 2AGMA 1EAKA 1OMJA 2O36A 4A7BA 2DW2A 3KEJA 4WKIA 1CGFA 1SU3A 4I35A 1ZTQA 3HDBA 2X7MA 1FLSA 1IADA 4G0DA 2FV9A 3LJTA 1XFZA 4J4MA 2L0RA 3K7LA 1GKDA 2Y6CA 3O2XA 1G12A 1XAXA 2USNA 2XS3A 3BA0A 2OZRA 1CGEA 3KECA 1PWVA 1K7IA 1CQRA 3HY9A 3B8ZA 2WO8A 2ML2A 4GWNA 2QUAA 5BPAA 3Q2HA 2WOAA 4G9LA 3NTNA 1SLMA 3KRYA 1GE5A 4HX3A 3DL1A 1IABA 1PWUA 1O0QA 2OVZA 1HFSA 2WO9A 3LQBA 4GR8A 2X3CA 3TT4A 3DTIA 3LGPA 3LUNA 3V96B 1RM8A 1H71P 3EHYA 1OO9A 966CA 4GUYA 4WK7A 1KUGA 3LIKA 4H76A 4CTHA 2MZHA 1SATA 3L0VA 3EWJA 2J83A 5I2ZA 1BKCI 2TCLA 1KUIA 4GR3A 1SLNA 4JA1A 1BQQM 3G5CA 5L7FA 3DSLA 1GO7P 2OI0A 1HV5A 4I03A 1IAGA 1AKLA 2OXWA
chains in the Genus database with same CATH topology
1G4KA 2W13A 3F18A 2W12A 1EUBA 4GF1A 2QPJA 1QUAA 1JAPA 4XM6A 2W14A 4HMAA 3KHIA 3F16A 1J7NA 4WF6A 1OS2A 5I12A 1XFYA 3LJGA 3HYGA 4XM7A 4PKWA 2Z8ZA 5BOTA 2X3AA 2ZJ6A 1ZS0A 5I43A 3AIGA 4DF9A 1R1IA 1USNA 3HBUP 3WP8A 1A85A 1EB6A 1BQOA 3LA9A 2CLTA 2Z2DA 1BUVM 3A70A 5D7WA 4H1QA 1YCMA 2OVXA 2ERPA 5JMYA 1UTTA 1Z3JA 5L79A 2MZIA 1WNIA 2OW0A 3U1RA 3LUMA 4H49A 2PJTA 3EDIA 1QJJA 3ZXHA 5I3MA 1L6JA 1QIAA 5D2BA 1QICA 5I4OA 4DV8A 2YO1A 2MLSA 1R55A 1ND1A 1PWWA 2JT5A 4JIJA 1K7QA 2D1OA 1GE6A 1ZXVA 4PKRA 1PWPA 2KRJA 2W0DA 3MA2A 4A3WA 3DPFA 1I1IP 4R3VA 2XS4A 2J0TA 4GR0A 4WKEA 2POJA 2OW9A 4FXYP 1KAPP 1C3IA 1JANA 3B92A 3F15A 3WV2A 3DPEA 4Q1LA 4AIGA 1MMQA 3SHIA 2RJPA 1IAEA 1G9KA 3LEAA 1JKYA 1OM7A 5CZMA 1RMZA 3I7GA 1BZSA 3P24A 2E3XA 2JSDA 4L7AA 1XFXA 4H82A 2OXZA 3DWBA 3AYKA 1P9HA 2OY4A 3ZVSA 3N2VA 4XM8A 1R1HA 1BKCE 3CKIA 1XURA 3DNGA 1K7GA 1FBLA 4AXQA 5CXAA 3HY7A 1ATLA 1C8TA 4FXQA 2O3EA 1SMPA 1C7KA 1QIBA 2CKIA 4ON1A 1IAAA 3F1AA 3E8RA 1JIWP 3LIRA 3EDZA 2I47A 2DW1A 1QJIA 5H8XA 4EFSA 3VI1A 5CUHA 3NX7A 1MMBA 1KUKA 4JP4A 2XQHA 2RJQA 2YIGA 2JIHA 4AYKA 3LMCA 4JPAA 4XCTA 2MZEA 4IUWA 1R1JA 1OM8A 2OW2A 4L6TA 2K2GA 2EROA 3GBOA 3B2ZA 1PWQA 3WV1A 1MMPA 1ROSA 1CAQA 2DDYA 1HFCA 5LABA 3UVCA 1CIZA 3EHXA 2DDFA 5D1SA 2OY2A 3HDAP 1GXDA 1OM6A 3EDHA 1BIWA 4WZVA 2ZVDA 4IJOA 3TS4A 1S4BP 1CK7A 2QUBA 4QKZA 5B5PA 4PKQA 1MMRA 2OW1A 1MNCA 4ZR5A 4FU4A 5CXLA 1ZP5A 1I76A 3KWVC 3F19A 3F17A 1I73A 1BKCA 5D1UA 1HY7A 2W15A 1CGLA 1BUDA 1YQYA 2V4BA 4H84A 1JJ9A 1UTZA 1YOUA 3LJZA 5D1TA 1CXVA 456CA 3HBVP 2HU6A 2X3BA 5B5OA 1OS9A 1HOVA 3AYUA 3ELMA 1R54A 3K7NA 2YUFA 3N2UA 3Q2GA 3ZUKA 3L0TA 1O0TA 1JAQA 1Y0VA 1ASTA 3RTTA 1GKCA 2AYKA 2YB9A 1XFVA 1B8YA 1ZVXA 1JH1A 2D1NA 4GQLA 2N8RA 2Y6DA 3DTEA 1ZXCA 2Z8XA 3KMCA 3I7IA 3VTGA 4PKUA 1Y93A 1JIZA 4PKTA 1Y8JA 1Q3AA 1KBCA 3KEKA 2E2DA 5BOYA 4XBHA 3LAAA 1D7XA 2MLRA 2DW0A 3LK8A 4FVLA 4IN9A 1JK3A 1FM1A 4H2EA 1A86A 1GO8P 1D8MA 3LE9A 1HTDA 2ERQA 2ZJ7A 4H30A 1XUCA 3WV3A 3S6LA 2K9CA 3LILA 3ULTA 1DMTA 1AYKA 2FV5A 2SRTA 2OXUA 2JNPA 1UMSA 1KUFA 3HB2P 2A8HA 3RTSA 830CA 1D5JA 3OHLA 3EDGA 5D3CA 4L19A 1UEAA 1XFUA 1KUHA 3LQ0A 3TSKA 1DTHA 1UMTA 1GE7A 1B3DA 1D8FA 4L63A 1JAOA 1G05A 1SRPA 3G42A 4DPEA 2YO0A 1XUDA 3OHOA 2JT6A 4H3XA 4DD8A 3P1VA 3TVCA 3A6ZA 1XFWA 3O64A 3DTKA 4ILWD 4PKSA 4GWMA 1YP1A 4PKVA 3LKAA 2AIGP 5CVWA 1IACA 1AF0A 3KMEA 4AUOA 4JQGA 1BSWA 3USNA 1BM6A 1G49A 5I0LA 2AGMA 1EAKA 1OMJA 2O36A 4A7BA 2DW2A 3KEJA 4WKIA 1CGFA 1SU3A 4I35A 1ZTQA 3HDBA 2X7MA 1FLSA 1IADA 4G0DA 2FV9A 3LJTA 1XFZA 4J4MA 2L0RA 3K7LA 1GKDA 2Y6CA 3O2XA 1G12A 2USNA 2XS3A 3BA0A 2OZRA 1CGEA 3KECA 1PWVA 1K7IA 1CQRA 3HY9A 3B8ZA 2WO8A 2ML2A 4GWNA 2QUAA 5BPAA 3Q2HA 2WOAA 4G9LA 3NTNA 1SLMA 3KRYA 1GE5A 4HX3A 3DL1A 1IABA 1PWUA 1O0QA 2OVZA 1HFSA 2WO9A 3LQBA 4GR8A 2X3CA 3TT4A 3DTIA 3LGPA 3LUNA 3V96B 1RM8A 1H71P 3EHYA 1OO9A 966CA 4GUYA 4WK7A 1KUGA 3LIKA 4H76A 4CTHA 2MZHA 1SATA 3L0VA 3EWJA 2J83A 5I2ZA 1BKCI 2TCLA 1KUIA 4GR3A 1SLNA 4JA1A 1BQQM 3G5CA 5L7FA 3DSLA 1GO7P 2OI0A 1HV5A 4I03A 1IAGA 1AKLA 2OXWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1G4K A;  2W13 A;  3F18 A;  2W12 A;  1EUB A;  4GF1 A;  2QPJ A;  1QUA A;  1JAP A;  4XM6 A;  2W14 A;  4HMA A;  3KHI A;  3F16 A;  1J7N A;  4WF6 A;  1OS2 A;  5I12 A;  1XFY A;  3LJG A;  3HYG A;  4XM7 A;  4PKW A;  2Z8Z A;  5BOT A;  2X3A A;  2ZJ6 A;  1ZS0 A;  5I43 A;  3AIG A;  4DF9 A;  1R1I A;  1USN A;  3HBU P;  3WP8 A;  1A85 A;  1EB6 A;  1BQO A;  3LA9 A;  2CLT A;  2Z2D A;  1BUV M;  3A70 A;  5D7W A;  4H1Q A;  1YCM A;  2OVX A;  2ERP A;  5JMY A;  1UTT A;  1Z3J A;  5L79 A;  2MZI A;  1WNI A;  2OW0 A;  3U1R A;  3LUM A;  4H49 A;  2PJT A;  3EDI A;  1QJJ A;  3ZXH A;  5I3M A;  1L6J A;  1QIA A;  5D2B A;  1QIC A;  5I4O A;  4DV8 A;  2YO1 A;  2MLS A;  1R55 A;  1ND1 A;  1PWW A;  2JT5 A;  4JIJ A;  1K7Q A;  2D1O A;  1GE6 A;  1ZXV A;  4PKR A;  1PWP A;  2KRJ A;  2W0D A;  3MA2 A;  4A3W A;  3DPF A;  1I1I P;  4R3V A;  2XS4 A;  2J0T A;  4GR0 A;  4WKE A;  2POJ A;  2OW9 A;  4FXY P;  1KAP P;  1C3I A;  1JAN A;  3B92 A;  3F15 A;  3WV2 A;  3DPE A;  4Q1L A;  4AIG A;  1MMQ A;  3SHI A;  2RJP A;  1IAE A;  1G9K A;  3LEA A;  1JKY A;  1OM7 A;  5CZM A;  1RMZ A;  3I7G A;  1BZS A;  3P24 A;  2E3X A;  2JSD A;  1XFX A;  4H82 A;  2OXZ A;  3DWB A;  3AYK A;  1P9H A;  2OY4 A;  3ZVS A;  3N2V A;  4XM8 A;  1R1H A;  1BKC E;  3CKI A;  1XUR A;  3DNG A;  1K7G A;  1FBL A;  4AXQ A;  5CXA A;  3HY7 A;  1ATL A;  1C8T A;  4FXQ A;  2O3E A;  1SMP A;  1C7K A;  1QIB A;  2CKI A;  4ON1 A;  1IAA A;  3F1A A;  3E8R A;  1JIW P;  3LIR A;  3EDZ A;  2I47 A;  2DW1 A;  1QJI A;  5H8X A;  4EFS A;  3VI1 A;  5CUH A;  3NX7 A;  1MMB A;  1KUK A;  4JP4 A;  2XQH A;  2RJQ A;  2YIG A;  2JIH A;  4AYK A;  3LMC A;  4JPA A;  4XCT A;  2MZE A;  4IUW A;  1R1J A;  1OM8 A;  2OW2 A;  4L6T A;  2K2G A;  2ERO A;  3GBO A;  3B2Z A;  1PWQ A;  3WV1 A;  1MMP A;  1ROS A;  1CAQ A;  2DDY A;  1HFC A;  5LAB A;  3UVC A;  1CIZ A;  3EHX A;  2DDF A;  5D1S A;  2OY2 A;  3HDA P;  1GXD A;  1OM6 A;  3EDH A;  1BIW A;  4WZV A;  2ZVD A;  4IJO A;  3TS4 A;  1S4B P;  1CK7 A;  2QUB A;  4QKZ A;  5B5P A;  4PKQ A;  1MMR A;  2OW1 A;  1MNC A;  4ZR5 A;  4FU4 A;  5CXL A;  1ZP5 A;  1I76 A;  3KWV C;  3F19 A;  3F17 A;  1I73 A;  1BKC A;  5D1U A;  1HY7 A;  2W15 A;  1CGL A;  1BUD A;  1YQY A;  2V4B A;  4H84 A;  1JJ9 A;  1UTZ A;  1YOU A;  3LJZ A;  5D1T A;  1CXV A;  456C A;  3HBV P;  2HU6 A;  2X3B A;  5B5O A;  1OS9 A;  1HOV A;  3AYU A;  3ELM A;  1R54 A;  3K7N A;  3N2U A;  3Q2G A;  3ZUK A;  3L0T A;  1O0T A;  1JAQ A;  1Y0V A;  1AST A;  3RTT A;  1GKC A;  2AYK A;  2YB9 A;  1XFV A;  1B8Y A;  1ZVX A;  1JH1 A;  2D1N A;  4GQL A;  2N8R A;  2Y6D A;  1ZXC A;  2Z8X A;  3KMC A;  3I7I A;  3VTG A;  4PKU A;  1Y93 A;  1JIZ A;  4PKT A;  1Y8J A;  1Q3A A;  1KBC A;  3KEK A;  2E2D A;  5BOY A;  4XBH A;  3LAA A;  1D7X A;  2MLR A;  2DW0 A;  3LK8 A;  4FVL A;  4IN9 A;  1JK3 A;  1FM1 A;  4H2E A;  1A86 A;  1GO8 P;  1D8M A;  3LE9 A;  1HTD A;  2ERQ A;  2ZJ7 A;  4H30 A;  1XUC A;  3WV3 A;  3S6L A;  2K9C A;  3LIL A;  3ULT A;  1DMT A;  1AYK A;  2FV5 A;  2SRT A;  2OXU A;  2JNP A;  1UMS A;  1KUF A;  3HB2 P;  2A8H A;  3RTS A;  830C A;  1D5J A;  3OHL A;  3EDG A;  5D3C A;  4L19 A;  1UEA A;  1XFU A;  1KUH A;  3LQ0 A;  3TSK A;  1DTH A;  1UMT A;  1GE7 A;  1B3D A;  1D8F A;  4L63 A;  1JAO A;  1G05 A;  1SRP A;  3G42 A;  4DPE A;  2YO0 A;  1XUD A;  3OHO A;  2JT6 A;  4H3X A;  4DD8 A;  3P1V A;  3TVC A;  3A6Z A;  1XFW A;  3O64 A;  4ILW D;  4PKS A;  4GWM A;  1YP1 A;  4PKV A;  3LKA A;  2AIG P;  5CVW A;  1IAC A;  1AF0 A;  3KME A;  4AUO A;  4JQG A;  1BSW A;  3USN A;  1BM6 A;  1G49 A;  5I0L A;  2AGM A;  1EAK A;  1OMJ A;  2O36 A;  4A7B A;  2DW2 A;  3KEJ A;  4WKI A;  1CGF A;  1SU3 A;  4I35 A;  1ZTQ A;  3HDB A;  2X7M A;  1FLS A;  1IAD A;  4G0D A;  2FV9 A;  3LJT A;  1XFZ A;  4J4M A;  2L0R A;  3K7L A;  1GKD A;  2Y6C A;  3O2X A;  1G12 A;  2USN A;  2XS3 A;  3BA0 A;  2OZR A;  1CGE A;  3KEC A;  1PWV A;  1K7I A;  1CQR A;  3HY9 A;  3B8Z A;  2WO8 A;  2ML2 A;  4GWN A;  2QUA A;  5BPA A;  3Q2H A;  2WOA A;  4G9L A;  3NTN A;  1SLM A;  3KRY A;  1GE5 A;  4HX3 A;  3DL1 A;  1IAB A;  1PWU A;  1O0Q A;  2OVZ A;  1HFS A;  2WO9 A;  3LQB A;  4GR8 A;  2X3C A;  3TT4 A;  3LGP A;  3LUN A;  3V96 B;  1RM8 A;  1H71 P;  3EHY A;  1OO9 A;  966C A;  4GUY A;  4WK7 A;  1KUG A;  3LIK A;  4H76 A;  4CTH A;  2MZH A;  1SAT A;  3L0V A;  3EWJ A;  2J83 A;  5I2Z A;  1BKC I;  2TCL A;  1KUI A;  4GR3 A;  1SLN A;  4JA1 A;  1BQQ M;  3G5C A;  5L7F A;  3DSL A;  1GO7 P;  2OI0 A;  1HV5 A;  4I03 A;  1IAG A;  1AKL A;  2OXW A; 
#chains in the Genus database with same CATH topology
 1G4K A;  2W13 A;  3F18 A;  2W12 A;  1EUB A;  4GF1 A;  2QPJ A;  1QUA A;  1JAP A;  4XM6 A;  2W14 A;  4HMA A;  3KHI A;  3F16 A;  1J7N A;  4WF6 A;  1OS2 A;  5I12 A;  1XFY A;  3LJG A;  3HYG A;  4XM7 A;  4PKW A;  2Z8Z A;  5BOT A;  2X3A A;  2ZJ6 A;  1ZS0 A;  5I43 A;  3AIG A;  4DF9 A;  1R1I A;  1USN A;  3HBU P;  3WP8 A;  1A85 A;  1EB6 A;  1BQO A;  3LA9 A;  2CLT A;  2Z2D A;  1BUV M;  3A70 A;  5D7W A;  4H1Q A;  1YCM A;  2OVX A;  2ERP A;  5JMY A;  1UTT A;  1Z3J A;  5L79 A;  1TVI A;  2MZI A;  1WNI A;  1XM5 A;  2OW0 A;  3U1R A;  3LUM A;  4H49 A;  2PJT A;  3EDI A;  1QJJ A;  3ZXH A;  5I3M A;  1L6J A;  1QIA A;  5D2B A;  1QIC A;  5I4O A;  4DV8 A;  2YO1 A;  2MLS A;  1R55 A;  1ND1 A;  1PWW A;  2JT5 A;  4JIJ A;  1K7Q A;  2D1O A;  1GE6 A;  1ZXV A;  4PKR A;  1PWP A;  2KRJ A;  2W0D A;  3MA2 A;  4A3W A;  3DPF A;  1I1I P;  4R3V A;  2XS4 A;  2J0T A;  4GR0 A;  4WKE A;  2POJ A;  2OW9 A;  4FXY P;  1KAP P;  1C3I A;  1JAN A;  3B92 A;  3F15 A;  3WV2 A;  3DPE A;  4Q1L A;  4AIG A;  1MMQ A;  3SHI A;  2RJP A;  1IAE A;  1G9K A;  3LEA A;  1JKY A;  1OM7 A;  5CZM A;  1RMZ A;  3I7G A;  1BZS A;  3P24 A;  2E3X A;  2JSD A;  4L7A A;  1XFX A;  4H82 A;  2OXZ A;  3DWB A;  3AYK A;  1P9H A;  2OY4 A;  3ZVS A;  3N2V A;  4XM8 A;  1R1H A;  1BKC E;  3CKI A;  1XUR A;  3DNG A;  1K7G A;  1FBL A;  4AXQ A;  5CXA A;  3HY7 A;  1ATL A;  1C8T A;  4FXQ A;  2O3E A;  1SMP A;  1C7K A;  1QIB A;  2CKI A;  4ON1 A;  1IAA A;  3F1A A;  3E8R A;  1JIW P;  3LIR A;  3EDZ A;  2I47 A;  2DW1 A;  1QJI A;  5H8X A;  4EFS A;  3VI1 A;  5CUH A;  3NX7 A;  1MMB A;  1KUK A;  4JP4 A;  2XQH A;  2RJQ A;  2YIG A;  2JIH A;  4AYK A;  3LMC A;  4JPA A;  4XCT A;  2MZE A;  4IUW A;  1R1J A;  1OM8 A;  2OW2 A;  4L6T A;  2K2G A;  2ERO A;  3GBO A;  3B2Z A;  1PWQ A;  3WV1 A;  1MMP A;  1ROS A;  1CAQ A;  2DDY A;  1HFC A;  5LAB A;  3UVC A;  1CIZ A;  3EHX A;  2DDF A;  5D1S A;  2OY2 A;  3HDA P;  1GXD A;  1OM6 A;  3EDH A;  1BIW A;  4WZV A;  2ZVD A;  4IJO A;  3TS4 A;  1S4B P;  1CK7 A;  2QUB A;  4QKZ A;  5B5P A;  4PKQ A;  1MMR A;  2OW1 A;  1MNC A;  4ZR5 A;  4FU4 A;  5CXL A;  1ZP5 A;  1I76 A;  3KWV C;  3F19 A;  3F17 A;  1I73 A;  1BKC A;  5D1U A;  1HY7 A;  2W15 A;  1CGL A;  1BUD A;  1YQY A;  2V4B A;  4H84 A;  1JJ9 A;  1UTZ A;  1YOU A;  3LJZ A;  5D1T A;  1CXV A;  456C A;  3HBV P;  2HU6 A;  2X3B A;  5B5O A;  1OS9 A;  1HOV A;  3AYU A;  3ELM A;  1R54 A;  3K7N A;  2YUF A;  3N2U A;  3Q2G A;  3ZUK A;  3L0T A;  1O0T A;  1JAQ A;  1Y0V A;  1AST A;  3RTT A;  1GKC A;  2AYK A;  2YB9 A;  1XFV A;  1B8Y A;  1ZVX A;  1JH1 A;  2D1N A;  4GQL A;  2N8R A;  2Y6D A;  3DTE A;  1ZXC A;  2Z8X A;  3KMC A;  3I7I A;  3VTG A;  4PKU A;  1Y93 A;  1JIZ A;  4PKT A;  1Y8J A;  1Q3A A;  1KBC A;  3KEK A;  2E2D A;  5BOY A;  4XBH A;  3LAA A;  1D7X A;  2MLR A;  2DW0 A;  1OZ9 A;  3LK8 A;  4FVL A;  4IN9 A;  1JK3 A;  1FM1 A;  4H2E A;  1A86 A;  1GO8 P;  1D8M A;  3LE9 A;  1HTD A;  2ERQ A;  2ZJ7 A;  4H30 A;  1XUC A;  3WV3 A;  3S6L A;  2K9C A;  3LIL A;  3ULT A;  1DMT A;  1AYK A;  2FV5 A;  2SRT A;  4DT5 A;  2OXU A;  2JNP A;  1UMS A;  1KUF A;  3HB2 P;  2A8H A;  3RTS A;  830C A;  1D5J A;  3OHL A;  3EDG A;  5D3C A;  4L19 A;  1UEA A;  1XFU A;  1KUH A;  3LQ0 A;  3TSK A;  1DTH A;  1UMT A;  1GE7 A;  1B3D A;  1D8F A;  4L63 A;  1JAO A;  1G05 A;  1SRP A;  3G42 A;  4DPE A;  2YO0 A;  1XUD A;  3OHO A;  2JT6 A;  4H3X A;  4DD8 A;  3P1V A;  3TVC A;  3A6Z A;  1XFW A;  3O64 A;  3DTK A;  4ILW D;  4PKS A;  4GWM A;  1YP1 A;  4PKV A;  3LKA A;  2AIG P;  5CVW A;  1IAC A;  1AF0 A;  3KME A;  4AUO A;  4JQG A;  1BSW A;  3USN A;  1BM6 A;  1G49 A;  5I0L A;  2AGM A;  1EAK A;  1OMJ A;  2O36 A;  4A7B A;  2DW2 A;  3KEJ A;  4WKI A;  1CGF A;  1SU3 A;  4I35 A;  1ZTQ A;  3HDB A;  2X7M A;  1FLS A;  1IAD A;  4G0D A;  2FV9 A;  3LJT A;  1XFZ A;  4J4M A;  2L0R A;  3K7L A;  1GKD A;  2Y6C A;  3O2X A;  1G12 A;  1XAX A;  2USN A;  2XS3 A;  3BA0 A;  2OZR A;  1CGE A;  3KEC A;  1PWV A;  1K7I A;  1CQR A;  3HY9 A;  3B8Z A;  2WO8 A;  2ML2 A;  4GWN A;  2QUA A;  5BPA A;  3Q2H A;  2WOA A;  4G9L A;  3NTN A;  1SLM A;  3KRY A;  1GE5 A;  4HX3 A;  3DL1 A;  1IAB A;  1PWU A;  1O0Q A;  2OVZ A;  1HFS A;  2WO9 A;  3LQB A;  4GR8 A;  2X3C A;  3TT4 A;  3DTI A;  3LGP A;  3LUN A;  3V96 B;  1RM8 A;  1H71 P;  3EHY A;  1OO9 A;  966C A;  4GUY A;  4WK7 A;  1KUG A;  3LIK A;  4H76 A;  4CTH A;  2MZH A;  1SAT A;  3L0V A;  3EWJ A;  2J83 A;  5I2Z A;  1BKC I;  2TCL A;  1KUI A;  4GR3 A;  1SLN A;  4JA1 A;  1BQQ M;  3G5C A;  5L7F A;  3DSL A;  1GO7 P;  2OI0 A;  1HV5 A;  4I03 A;  1IAG A;  1AKL A;  2OXW A; 
#chains in the Genus database with same CATH homology
 1G4K A;  2W13 A;  3F18 A;  2W12 A;  1EUB A;  4GF1 A;  2QPJ A;  1QUA A;  1JAP A;  4XM6 A;  2W14 A;  4HMA A;  3KHI A;  3F16 A;  1J7N A;  4WF6 A;  1OS2 A;  5I12 A;  1XFY A;  3LJG A;  3HYG A;  4XM7 A;  4PKW A;  2Z8Z A;  5BOT A;  2X3A A;  2ZJ6 A;  1ZS0 A;  5I43 A;  3AIG A;  4DF9 A;  1R1I A;  1USN A;  3HBU P;  3WP8 A;  1A85 A;  1EB6 A;  1BQO A;  3LA9 A;  2CLT A;  2Z2D A;  1BUV M;  3A70 A;  5D7W A;  4H1Q A;  1YCM A;  2OVX A;  2ERP A;  5JMY A;  1UTT A;  1Z3J A;  5L79 A;  2MZI A;  1WNI A;  2OW0 A;  3U1R A;  3LUM A;  4H49 A;  2PJT A;  3EDI A;  1QJJ A;  3ZXH A;  5I3M A;  1L6J A;  1QIA A;  5D2B A;  1QIC A;  5I4O A;  4DV8 A;  2YO1 A;  2MLS A;  1R55 A;  1ND1 A;  1PWW A;  2JT5 A;  4JIJ A;  1K7Q A;  2D1O A;  1GE6 A;  1ZXV A;  4PKR A;  1PWP A;  2KRJ A;  2W0D A;  3MA2 A;  4A3W A;  3DPF A;  1I1I P;  4R3V A;  2XS4 A;  2J0T A;  4GR0 A;  4WKE A;  2POJ A;  2OW9 A;  4FXY P;  1KAP P;  1C3I A;  1JAN A;  3B92 A;  3F15 A;  3WV2 A;  3DPE A;  4Q1L A;  4AIG A;  1MMQ A;  3SHI A;  2RJP A;  1IAE A;  1G9K A;  3LEA A;  1JKY A;  1OM7 A;  5CZM A;  1RMZ A;  3I7G A;  1BZS A;  3P24 A;  2E3X A;  2JSD A;  4L7A A;  1XFX A;  4H82 A;  2OXZ A;  3DWB A;  3AYK A;  1P9H A;  2OY4 A;  3ZVS A;  3N2V A;  4XM8 A;  1R1H A;  1BKC E;  3CKI A;  1XUR A;  3DNG A;  1K7G A;  1FBL A;  4AXQ A;  5CXA A;  3HY7 A;  1ATL A;  1C8T A;  4FXQ A;  2O3E A;  1SMP A;  1C7K A;  1QIB A;  2CKI A;  4ON1 A;  1IAA A;  3F1A A;  3E8R A;  1JIW P;  3LIR A;  3EDZ A;  2I47 A;  2DW1 A;  1QJI A;  5H8X A;  4EFS A;  3VI1 A;  5CUH A;  3NX7 A;  1MMB A;  1KUK A;  4JP4 A;  2XQH A;  2RJQ A;  2YIG A;  2JIH A;  4AYK A;  3LMC A;  4JPA A;  4XCT A;  2MZE A;  4IUW A;  1R1J A;  1OM8 A;  2OW2 A;  4L6T A;  2K2G A;  2ERO A;  3GBO A;  3B2Z A;  1PWQ A;  3WV1 A;  1MMP A;  1ROS A;  1CAQ A;  2DDY A;  1HFC A;  5LAB A;  3UVC A;  1CIZ A;  3EHX A;  2DDF A;  5D1S A;  2OY2 A;  3HDA P;  1GXD A;  1OM6 A;  3EDH A;  1BIW A;  4WZV A;  2ZVD A;  4IJO A;  3TS4 A;  1S4B P;  1CK7 A;  2QUB A;  4QKZ A;  5B5P A;  4PKQ A;  1MMR A;  2OW1 A;  1MNC A;  4ZR5 A;  4FU4 A;  5CXL A;  1ZP5 A;  1I76 A;  3KWV C;  3F19 A;  3F17 A;  1I73 A;  1BKC A;  5D1U A;  1HY7 A;  2W15 A;  1CGL A;  1BUD A;  1YQY A;  2V4B A;  4H84 A;  1JJ9 A;  1UTZ A;  1YOU A;  3LJZ A;  5D1T A;  1CXV A;  456C A;  3HBV P;  2HU6 A;  2X3B A;  5B5O A;  1OS9 A;  1HOV A;  3AYU A;  3ELM A;  1R54 A;  3K7N A;  2YUF A;  3N2U A;  3Q2G A;  3ZUK A;  3L0T A;  1O0T A;  1JAQ A;  1Y0V A;  1AST A;  3RTT A;  1GKC A;  2AYK A;  2YB9 A;  1XFV A;  1B8Y A;  1ZVX A;  1JH1 A;  2D1N A;  4GQL A;  2N8R A;  2Y6D A;  3DTE A;  1ZXC A;  2Z8X A;  3KMC A;  3I7I A;  3VTG A;  4PKU A;  1Y93 A;  1JIZ A;  4PKT A;  1Y8J A;  1Q3A A;  1KBC A;  3KEK A;  2E2D A;  5BOY A;  4XBH A;  3LAA A;  1D7X A;  2MLR A;  2DW0 A;  3LK8 A;  4FVL A;  4IN9 A;  1JK3 A;  1FM1 A;  4H2E A;  1A86 A;  1GO8 P;  1D8M A;  3LE9 A;  1HTD A;  2ERQ A;  2ZJ7 A;  4H30 A;  1XUC A;  3WV3 A;  3S6L A;  2K9C A;  3LIL A;  3ULT A;  1DMT A;  1AYK A;  2FV5 A;  2SRT A;  2OXU A;  2JNP A;  1UMS A;  1KUF A;  3HB2 P;  2A8H A;  3RTS A;  830C A;  1D5J A;  3OHL A;  3EDG A;  5D3C A;  4L19 A;  1UEA A;  1XFU A;  1KUH A;  3LQ0 A;  3TSK A;  1DTH A;  1UMT A;  1GE7 A;  1B3D A;  1D8F A;  4L63 A;  1JAO A;  1G05 A;  1SRP A;  3G42 A;  4DPE A;  2YO0 A;  1XUD A;  3OHO A;  2JT6 A;  4H3X A;  4DD8 A;  3P1V A;  3TVC A;  3A6Z A;  1XFW A;  3O64 A;  3DTK A;  4ILW D;  4PKS A;  4GWM A;  1YP1 A;  4PKV A;  3LKA A;  2AIG P;  5CVW A;  1IAC A;  1AF0 A;  3KME A;  4AUO A;  4JQG A;  1BSW A;  3USN A;  1BM6 A;  1G49 A;  5I0L A;  2AGM A;  1EAK A;  1OMJ A;  2O36 A;  4A7B A;  2DW2 A;  3KEJ A;  4WKI A;  1CGF A;  1SU3 A;  4I35 A;  1ZTQ A;  3HDB A;  2X7M A;  1FLS A;  1IAD A;  4G0D A;  2FV9 A;  3LJT A;  1XFZ A;  4J4M A;  2L0R A;  3K7L A;  1GKD A;  2Y6C A;  3O2X A;  1G12 A;  2USN A;  2XS3 A;  3BA0 A;  2OZR A;  1CGE A;  3KEC A;  1PWV A;  1K7I A;  1CQR A;  3HY9 A;  3B8Z A;  2WO8 A;  2ML2 A;  4GWN A;  2QUA A;  5BPA A;  3Q2H A;  2WOA A;  4G9L A;  3NTN A;  1SLM A;  3KRY A;  1GE5 A;  4HX3 A;  3DL1 A;  1IAB A;  1PWU A;  1O0Q A;  2OVZ A;  1HFS A;  2WO9 A;  3LQB A;  4GR8 A;  2X3C A;  3TT4 A;  3DTI A;  3LGP A;  3LUN A;  3V96 B;  1RM8 A;  1H71 P;  3EHY A;  1OO9 A;  966C A;  4GUY A;  4WK7 A;  1KUG A;  3LIK A;  4H76 A;  4CTH A;  2MZH A;  1SAT A;  3L0V A;  3EWJ A;  2J83 A;  5I2Z A;  1BKC I;  2TCL A;  1KUI A;  4GR3 A;  1SLN A;  4JA1 A;  1BQQ M;  3G5C A;  5L7F A;  3DSL A;  1GO7 P;  2OI0 A;  1HV5 A;  4I03 A;  1IAG A;  1AKL A;  2OXW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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