1O99A

Crystal structure of the s62a mutant of phosphoglycerate mutase from bacillus stearothermophilus complexed with 2-phosphoglycerate
Total Genus 195
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
195
Knots found
sequence length
509
structure length
509
Chain Sequence
SKKPVALIILDGFALRDETYGNAVAQANKPNFDRYWNEYPHTTLKACGEAVGLPEGQMGNAEVGHLNIGAGRIVYQSLTRINIAIREGEFDRNETFLAAMNHVKQHGTSLHLFGLLSDGGVHSHIHHLYALLRLAAKEGVKRVYIHGFLDGRDVGPQTAPQYIKELQEKIKEYGVGEIATLSGRYYSMDRDKRWDRVEKAYRAMVYGEGPTYRDPLECIEDSYKHGIYDEFVLPSVIVREDGRPVATIQDNDAIIFYNFRPDRAIQISNTFTNEDFREFDRGPKHPKHLFFVCLTHFSETVAGYVAFKPTNLDNTIGEVLSQHGLRQLRIAETEKYPHVTFFMSGGREEEFPGEDRILINSPKVPTYDLKPEMSAYEVTDALLKEIEADKYDAIILNYANPDMVGHSGKLEPTIKAVEAVDECLGKVVDAILAKGGIAIITADHGNADEVLTPDGKPQTAHTTNPVPVIVTKKGIKLRDGGILGDLAPTMLDLLGLPQPKEMTGKSLIV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Insights Into the Catalytic Mechanism of Cofactor-Independent Phosphoglycerate Mutase from X-Ray Crystallography, Simulated Dynamics and Molecular Modeling
pubmed doi rcsb
source organism Bacillus stearothermophilus
molecule tags Isomerase
molecule keywords 2,3-BISPHOSPHOGLYCERATE-INDEPENDENT PHOSPHOGLYCERATE MUTASE
total genus 195
structure length 509
sequence length 509
other databases KnotProt 2.0: S +31
ec nomenclature ec 5.4.2.12: Phosphoglycerate mutase (2,3-diphosphoglycerate-independent).
pdb deposition date 2002-12-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01676 Metalloenzyme Metalloenzyme superfamily
A PF06415 iPGM_N BPG-independent PGAM N-terminus (iPGM_N)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1o99A02
3.40.1450.10 Alpha Beta 3-Layer(aba) Sandwich 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain BPG-independent phosphoglycerate mutase, domain B 1o99A01
4LR7A 2ZKTA 1E3CP 3M8YA 3A52A 5EGHA 2D1GA 1ZEBA 3WAWA 4CYSA 4CYRA 2W8SA 4LREA 4UPLA 5L0BA 2XR9A 3WAXA 5AJ9A 5LRMA 4UORA 1E2SP 3Q3QA 5DLWA 1ANJA 1ANIA 4FDJA 3BDGA 5HRTA 1ELXA 5C66A 2W5SA 3MK1A 3WAVA 2IUCA 4LRFA 5DLTA 3NKPA 4NWXA 5GOVA 5LQQA 4ZG9A 5LIAA 2W5XA 4MHXA 2W5RA 2W5QA 3LXQA 4MY4A 1KH5A 1ED9A 4UPKA 1E1ZP 1AUKA 3WBHA 3IGZB 1KHNA 2GLQA 3MK0A 4LRAA 1ED8A 3WAYA 1URBA 4N7TA 1AJBA 4QAXA 5IJQA 3BDHA 3BDFA 3UN2A 3DYCA 1B8JA 2IUCB 4GTZA 1ALHA 3MK2A 3NKQA 4CXUA 4ZG6A 3SZYA 1EW8A 5L0KA 4LQYA 2ANHA 1EJJA 4CXSA 5L0EA 1KHLA 1HDHA 1ELYA 4LRCA 2W5WA 1KH7A 4LR2A 1KH4A 1EI6A 4KJGA 3T02A 5LRNA 3B5QA 2W8DA 1SHNA 3M7VA 3BDGB 2RH6A 1AJCA 4YR1A 1KHJA 3TG0A 4KM4A 2IFYA 1K7HA 1HQAA 5K4PA 3KD8A 1Y6VA 3NKRA 1N2KA 4LRBA 4LR8A 4NWJA 4KAVA 3UN5A 1URAA 2QZUA 1AJAA 3UN3A 2W5VA 2X98A 5IJSA 3NVLA 1SHQA 1ALKA 3NKNA 4GTYA 2XRGA 1AJDA 2GSUA 1KH9A 3ED4A 5DLVA 3UNYA 1EW9A 1EQJA 3M8ZA 4ZGAA 3IGYB 3SZZA 1ZEFA 4GTXA 4UPIA 2W5TA 3DPCA 3T01A 4UPHA 1O99A 3UO0A 1FSUA 4MIVA 2GSOA 1KHKA 5KXAA 2VQRA 3TWZA 1ELZA 3M8WA 1P49A 5EGEA 4UOOA 3E2DA 4LRDA 1N2LA 2GA3A 4FDIA 4ZG7A 3NKMA 1E33P 3IDDA 1ZEDA 3TX0A 5TJ3A 5GRRA 4TN0A 3T00A 1O98A 1ALIA 3CMRA 1Y7AA 2G9YA 4KAYA 3NKOA 4LR9A 4CXKA 5INHA 4GTWA 4B56A 2GSNA 1HJKA 1ALJA 1EW2A 3OT9A 4KJDA 4UOPA
chains in the Genus database with same CATH superfamily
4LR7A 2ZKTA 1E3CP 3M8YA 3A52A 5EGHA 2D1GA 1ZEBA 3WAWA 4CYSA 4CYRA 2W8SA 4LREA 4UPLA 5L0BA 2XR9A 3WAXA 5AJ9A 5LRMA 4UORA 1E2SP 3Q3QA 5DLWA 1ANJA 1ANIA 4FDJA 3BDGA 5HRTA 1ELXA 5C66A 2W5SA 3MK1A 3WAVA 2IUCA 4LRFA 5DLTA 3NKPA 4NWXA 5GOVA 5LQQA 4ZG9A 5LIAA 2W5XA 4MHXA 2W5RA 2W5QA 3LXQA 4MY4A 1KH5A 1ED9A 4UPKA 1E1ZP 1AUKA 3WBHA 3IGZB 1KHNA 2GLQA 3MK0A 4LRAA 1ED8A 3WAYA 1URBA 4N7TA 1AJBA 4QAXA 5IJQA 3BDHA 3BDFA 3UN2A 3DYCA 1B8JA 2IUCB 4GTZA 1ALHA 3MK2A 3NKQA 4CXUA 4ZG6A 3SZYA 1EW8A 5L0KA 4LQYA 2ANHA 1EJJA 4CXSA 5L0EA 1KHLA 1HDHA 1ELYA 4LRCA 2W5WA 1KH7A 4LR2A 1KH4A 1EI6A 4KJGA 3T02A 5LRNA 3B5QA 2W8DA 1SHNA 3M7VA 3BDGB 2RH6A 1AJCA 4YR1A 1KHJA 3TG0A 4KM4A 2IFYA 1K7HA 1HQAA 5K4PA 3KD8A 1Y6VA 3NKRA 1N2KA 4LRBA 4LR8A 4NWJA 4KAVA 3UN5A 1URAA 2QZUA 1AJAA 3UN3A 2W5VA 2X98A 5IJSA 3NVLA 1SHQA 1ALKA 3NKNA 4GTYA 2XRGA 1AJDA 2GSUA 1KH9A 3ED4A 5DLVA 3UNYA 1EW9A 1EQJA 3M8ZA 4ZGAA 3IGYB 3SZZA 1ZEFA 4GTXA 4UPIA 2W5TA 3DPCA 3T01A 4UPHA 1O99A 3UO0A 1FSUA 4MIVA 2GSOA 1KHKA 5KXAA 2VQRA 3TWZA 1ELZA 3M8WA 1P49A 5EGEA 4UOOA 3E2DA 4LRDA 1N2LA 2GA3A 4FDIA 4ZG7A 3NKMA 1E33P 3IDDA 1ZEDA 3TX0A 5TJ3A 5GRRA 4TN0A 3T00A 1O98A 1ALIA 3CMRA 1Y7AA 2G9YA 4KAYA 3NKOA 4LR9A 4CXKA 5INHA 4GTWA 4B56A 2GSNA 1HJKA 1ALJA 1EW2A 3OT9A 4KJDA 4UOPA
chains in the Genus database with same CATH topology
4LR7A 2ZKTA 1E3CP 3M8YA 3A52A 5EGHA 2D1GA 1ZEBA 3WAWA 4CYSA 4CYRA 2W8SA 4LREA 4UPLA 5L0BA 2XR9A 3WAXA 5AJ9A 5LRMA 4UORA 1E2SP 3Q3QA 5DLWA 1ANJA 1ANIA 4FDJA 3BDGA 5HRTA 1ELXA 5C66A 2W5SA 3MK1A 3WAVA 2IUCA 4LRFA 5DLTA 3NKPA 4NWXA 5GOVA 5LQQA 4ZG9A 5LIAA 2W5XA 4MHXA 2W5RA 2W5QA 3LXQA 4MY4A 1KH5A 1ED9A 4UPKA 1E1ZP 1AUKA 3WBHA 3IGZB 1KHNA 2GLQA 3MK0A 4LRAA 1ED8A 3WAYA 1URBA 4N7TA 1AJBA 4QAXA 5IJQA 3BDHA 3BDFA 3UN2A 3DYCA 1B8JA 2IUCB 4GTZA 1ALHA 3MK2A 3NKQA 4CXUA 4ZG6A 3SZYA 1EW8A 5L0KA 4LQYA 2ANHA 1EJJA 4CXSA 5L0EA 1KHLA 1HDHA 1ELYA 4LRCA 2W5WA 1KH7A 4LR2A 1KH4A 1EI6A 4KJGA 3T02A 5LRNA 3B5QA 2W8DA 1SHNA 3M7VA 3BDGB 2RH6A 1AJCA 4YR1A 1KHJA 3TG0A 4KM4A 2IFYA 1K7HA 1HQAA 5K4PA 3KD8A 1Y6VA 3NKRA 1N2KA 4LRBA 4LR8A 4NWJA 4KAVA 3UN5A 1URAA 2QZUA 1AJAA 3UN3A 2W5VA 2X98A 5IJSA 3NVLA 1SHQA 1ALKA 3NKNA 4GTYA 2XRGA 1AJDA 2GSUA 1KH9A 3ED4A 5DLVA 3UNYA 1EW9A 1EQJA 3M8ZA 4ZGAA 3IGYB 3SZZA 1ZEFA 4GTXA 4UPIA 2W5TA 3DPCA 3T01A 4UPHA 1O99A 3UO0A 1FSUA 4MIVA 2GSOA 1KHKA 5KXAA 2VQRA 3TWZA 1ELZA 3M8WA 1P49A 5EGEA 4UOOA 3E2DA 4LRDA 1N2LA 2GA3A 4FDIA 4ZG7A 3NKMA 1E33P 3IDDA 1ZEDA 3TX0A 5TJ3A 5GRRA 4TN0A 3T00A 1O98A 1ALIA 3CMRA 1Y7AA 2G9YA 4KAYA 3NKOA 4LR9A 4CXKA 5INHA 4GTWA 4B56A 2GSNA 1HJKA 1ALJA 1EW2A 3OT9A 4KJDA 4UOPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LR7 A;  2ZKT A;  1E3C P;  3M8Y A;  3A52 A;  5EGH A;  2D1G A;  1ZEB A;  3WAW A;  4CYS A;  4CYR A;  2W8S A;  4LRE A;  4UPL A;  5L0B A;  2XR9 A;  3WAX A;  5AJ9 A;  5LRM A;  4UOR A;  1E2S P;  3Q3Q A;  5DLW A;  1ANJ A;  1ANI A;  4FDJ A;  3BDG A;  5HRT A;  1ELX A;  5C66 A;  2W5S A;  3MK1 A;  3WAV A;  2IUC A;  4LRF A;  5DLT A;  3NKP A;  4NWX A;  5GOV A;  5LQQ A;  4ZG9 A;  5LIA A;  2W5X A;  4MHX A;  2W5R A;  2W5Q A;  3LXQ A;  4MY4 A;  1KH5 A;  1ED9 A;  4UPK A;  1E1Z P;  1AUK A;  3WBH A;  3IGZ B;  1KHN A;  2GLQ A;  3MK0 A;  4LRA A;  1ED8 A;  3WAY A;  1URB A;  4N7T A;  1AJB A;  4QAX A;  5IJQ A;  3BDH A;  3BDF A;  3UN2 A;  3DYC A;  1B8J A;  2IUC B;  4GTZ A;  1ALH A;  3MK2 A;  3NKQ A;  4CXU A;  4ZG6 A;  3SZY A;  1EW8 A;  5L0K A;  4LQY A;  2ANH A;  1EJJ A;  4CXS A;  5L0E A;  1KHL A;  1HDH A;  1ELY A;  4LRC A;  2W5W A;  1KH7 A;  4LR2 A;  1KH4 A;  1EI6 A;  4KJG A;  3T02 A;  5LRN A;  3B5Q A;  2W8D A;  1SHN A;  3M7V A;  3BDG B;  2RH6 A;  1AJC A;  4YR1 A;  1KHJ A;  3TG0 A;  4KM4 A;  2IFY A;  1K7H A;  1HQA A;  5K4P A;  3KD8 A;  1Y6V A;  3NKR A;  1N2K A;  4LRB A;  4LR8 A;  4NWJ A;  4KAV A;  3UN5 A;  1URA A;  2QZU A;  1AJA A;  3UN3 A;  2W5V A;  2X98 A;  5IJS A;  3NVL A;  1SHQ A;  1ALK A;  3NKN A;  4GTY A;  2XRG A;  1AJD A;  2GSU A;  1KH9 A;  3ED4 A;  5DLV A;  3UNY A;  1EW9 A;  1EQJ A;  3M8Z A;  4ZGA A;  3IGY B;  3SZZ A;  1ZEF A;  4GTX A;  4UPI A;  2W5T A;  3DPC A;  3T01 A;  4UPH A;  1O99 A;  3UO0 A;  1FSU A;  4MIV A;  2GSO A;  1KHK A;  5KXA A;  2VQR A;  3TWZ A;  1ELZ A;  3M8W A;  1P49 A;  5EGE A;  4UOO A;  3E2D A;  4LRD A;  1N2L A;  2GA3 A;  4FDI A;  4ZG7 A;  3NKM A;  1E33 P;  3IDD A;  1ZED A;  3TX0 A;  5TJ3 A;  5GRR A;  4TN0 A;  3T00 A;  1O98 A;  1ALI A;  3CMR A;  1Y7A A;  2G9Y A;  4KAY A;  3NKO A;  4LR9 A;  4CXK A;  5INH A;  4GTW A;  4B56 A;  2GSN A;  1HJK A;  1ALJ A;  1EW2 A;  3OT9 A;  4KJD A;  4UOP A; 
#chains in the Genus database with same CATH topology
 4LR7 A;  2ZKT A;  1E3C P;  3M8Y A;  3A52 A;  5EGH A;  2D1G A;  1ZEB A;  3WAW A;  4CYS A;  4CYR A;  2W8S A;  4LRE A;  4UPL A;  5L0B A;  2XR9 A;  3WAX A;  5AJ9 A;  5LRM A;  4UOR A;  1E2S P;  3Q3Q A;  5DLW A;  1ANJ A;  1ANI A;  4FDJ A;  3BDG A;  5HRT A;  1ELX A;  5C66 A;  2W5S A;  3MK1 A;  3WAV A;  2IUC A;  4LRF A;  5DLT A;  3NKP A;  4NWX A;  5GOV A;  5LQQ A;  4ZG9 A;  5LIA A;  2W5X A;  4MHX A;  2W5R A;  2W5Q A;  3LXQ A;  4MY4 A;  1KH5 A;  1ED9 A;  4UPK A;  1E1Z P;  1AUK A;  3WBH A;  3IGZ B;  1KHN A;  2GLQ A;  3MK0 A;  4LRA A;  1ED8 A;  3WAY A;  1URB A;  4N7T A;  1AJB A;  4QAX A;  5IJQ A;  3BDH A;  3BDF A;  3UN2 A;  3DYC A;  1B8J A;  2IUC B;  4GTZ A;  1ALH A;  3MK2 A;  3NKQ A;  4CXU A;  4ZG6 A;  3SZY A;  1EW8 A;  5L0K A;  4LQY A;  2ANH A;  1EJJ A;  4CXS A;  5L0E A;  1KHL A;  1HDH A;  1ELY A;  4LRC A;  2W5W A;  1KH7 A;  4LR2 A;  1KH4 A;  1EI6 A;  4KJG A;  3T02 A;  5LRN A;  3B5Q A;  2W8D A;  1SHN A;  3M7V A;  3BDG B;  2RH6 A;  1AJC A;  4YR1 A;  1KHJ A;  3TG0 A;  4KM4 A;  2IFY A;  1K7H A;  1HQA A;  5K4P A;  3KD8 A;  1Y6V A;  3NKR A;  1N2K A;  4LRB A;  4LR8 A;  4NWJ A;  4KAV A;  3UN5 A;  1URA A;  2QZU A;  1AJA A;  3UN3 A;  2W5V A;  2X98 A;  5IJS A;  3NVL A;  1SHQ A;  1ALK A;  3NKN A;  4GTY A;  2XRG A;  1AJD A;  2GSU A;  1KH9 A;  3ED4 A;  5DLV A;  3UNY A;  1EW9 A;  1EQJ A;  3M8Z A;  4ZGA A;  3IGY B;  3SZZ A;  1ZEF A;  4GTX A;  4UPI A;  2W5T A;  3DPC A;  3T01 A;  4UPH A;  1O99 A;  3UO0 A;  1FSU A;  4MIV A;  2GSO A;  1KHK A;  5KXA A;  2VQR A;  3TWZ A;  1ELZ A;  3M8W A;  1P49 A;  5EGE A;  4UOO A;  3E2D A;  4LRD A;  1N2L A;  2GA3 A;  4FDI A;  4ZG7 A;  3NKM A;  1E33 P;  3IDD A;  1ZED A;  3TX0 A;  5TJ3 A;  5GRR A;  4TN0 A;  3T00 A;  1O98 A;  1ALI A;  3CMR A;  1Y7A A;  2G9Y A;  4KAY A;  3NKO A;  4LR9 A;  4CXK A;  5INH A;  4GTW A;  4B56 A;  2GSN A;  1HJK A;  1ALJ A;  1EW2 A;  3OT9 A;  4KJD A;  4UOP A; 
#chains in the Genus database with same CATH homology
 4LR7 A;  2ZKT A;  1E3C P;  3M8Y A;  3A52 A;  5EGH A;  2D1G A;  1ZEB A;  3WAW A;  4CYS A;  4CYR A;  2W8S A;  4LRE A;  4UPL A;  5L0B A;  2XR9 A;  3WAX A;  5AJ9 A;  5LRM A;  4UOR A;  1E2S P;  3Q3Q A;  5DLW A;  1ANJ A;  1ANI A;  4FDJ A;  3BDG A;  5HRT A;  1ELX A;  5C66 A;  2W5S A;  3MK1 A;  3WAV A;  2IUC A;  4LRF A;  5DLT A;  3NKP A;  4NWX A;  5GOV A;  5LQQ A;  4ZG9 A;  5LIA A;  2W5X A;  4MHX A;  2W5R A;  2W5Q A;  3LXQ A;  4MY4 A;  1KH5 A;  1ED9 A;  4UPK A;  1E1Z P;  1AUK A;  3WBH A;  3IGZ B;  1KHN A;  2GLQ A;  3MK0 A;  4LRA A;  1ED8 A;  3WAY A;  1URB A;  4N7T A;  1AJB A;  4QAX A;  5IJQ A;  3BDH A;  3BDF A;  3UN2 A;  3DYC A;  1B8J A;  2IUC B;  4GTZ A;  1ALH A;  3MK2 A;  3NKQ A;  4CXU A;  4ZG6 A;  3SZY A;  1EW8 A;  5L0K A;  4LQY A;  2ANH A;  1EJJ A;  4CXS A;  5L0E A;  1KHL A;  1HDH A;  1ELY A;  4LRC A;  2W5W A;  1KH7 A;  4LR2 A;  1KH4 A;  1EI6 A;  4KJG A;  3T02 A;  5LRN A;  3B5Q A;  2W8D A;  1SHN A;  3M7V A;  3BDG B;  2RH6 A;  1AJC A;  4YR1 A;  1KHJ A;  3TG0 A;  4KM4 A;  2IFY A;  1K7H A;  1HQA A;  5K4P A;  3KD8 A;  1Y6V A;  3NKR A;  1N2K A;  4LRB A;  4LR8 A;  4NWJ A;  4KAV A;  3UN5 A;  1URA A;  2QZU A;  1AJA A;  3UN3 A;  2W5V A;  2X98 A;  5IJS A;  3NVL A;  1SHQ A;  1ALK A;  3NKN A;  4GTY A;  2XRG A;  1AJD A;  2GSU A;  1KH9 A;  3ED4 A;  5DLV A;  3UNY A;  1EW9 A;  1EQJ A;  3M8Z A;  4ZGA A;  3IGY B;  3SZZ A;  1ZEF A;  4GTX A;  4UPI A;  2W5T A;  3DPC A;  3T01 A;  4UPH A;  1O99 A;  3UO0 A;  1FSU A;  4MIV A;  2GSO A;  1KHK A;  5KXA A;  2VQR A;  3TWZ A;  1ELZ A;  3M8W A;  1P49 A;  5EGE A;  4UOO A;  3E2D A;  4LRD A;  1N2L A;  2GA3 A;  4FDI A;  4ZG7 A;  3NKM A;  1E33 P;  3IDD A;  1ZED A;  3TX0 A;  5TJ3 A;  5GRR A;  4TN0 A;  3T00 A;  1O98 A;  1ALI A;  3CMR A;  1Y7A A;  2G9Y A;  4KAY A;  3NKO A;  4LR9 A;  4CXK A;  5INH A;  4GTW A;  4B56 A;  2GSN A;  1HJK A;  1ALJ A;  1EW2 A;  3OT9 A;  4KJD A;  4UOP A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...