1O99A

Crystal structure of the s62a mutant of phosphoglycerate mutase from bacillus stearothermophilus complexed with 2-phosphoglycerate
Total Genus 195
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
195
Knots found
sequence length
509
structure length
509
Chain Sequence
SKKPVALIILDGFALRDETYGNAVAQANKPNFDRYWNEYPHTTLKACGEAVGLPEGQMGNAEVGHLNIGAGRIVYQSLTRINIAIREGEFDRNETFLAAMNHVKQHGTSLHLFGLLSDGGVHSHIHHLYALLRLAAKEGVKRVYIHGFLDGRDVGPQTAPQYIKELQEKIKEYGVGEIATLSGRYYSMDRDKRWDRVEKAYRAMVYGEGPTYRDPLECIEDSYKHGIYDEFVLPSVIVREDGRPVATIQDNDAIIFYNFRPDRAIQISNTFTNEDFREFDRGPKHPKHLFFVCLTHFSETVAGYVAFKPTNLDNTIGEVLSQHGLRQLRIAETEKYPHVTFFMSGGREEEFPGEDRILINSPKVPTYDLKPEMSAYEVTDALLKEIEADKYDAIILNYANPDMVGHSGKLEPTIKAVEAVDECLGKVVDAILAKGGIAIITADHGNADEVLTPDGKPQTAHTTNPVPVIVTKKGIKLRDGGILGDLAPTMLDLLGLPQPKEMTGKSLIV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords 2,3-BISPHOSPHOGLYCERATE-INDEPENDENT PHOSPHOGLYCERATE MUTASE
publication title Insights Into the Catalytic Mechanism of Cofactor-Independent Phosphoglycerate Mutase from X-Ray Crystallography, Simulated Dynamics and Molecular Modeling
pubmed doi rcsb
source organism Bacillus stearothermophilus
molecule tags Isomerase
total genus 195
structure length 509
sequence length 509
other databases KnotProt 2.0: S +31
ec nomenclature ec 5.4.2.12: Phosphoglycerate mutase (2,3-diphosphoglycerate-independent).
pdb deposition date 2002-12-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01676 Metalloenzyme Metalloenzyme superfamily
A PF06415 iPGM_N BPG-independent PGAM N-terminus (iPGM_N)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1o99A02
3.40.1450.10 Alpha Beta 3-Layer(aba) Sandwich 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain BPG-independent phosphoglycerate mutase, domain B 1o99A01
2GSUA 4KAVA 5HRTA 1B8JA 3TX0A 4CYSA 4LRFA 4UORA 4YR1A 1KHNA 3BDGB 4NWJA 4CXUA 3T00A 1ELZA 3NKRA 5LRNA 1KHJA 4LRCA 3DYCA 4LREA 1AJDA 1EW9A 2W5XA 3Q3QA 1KH4A 5K4PA 1KH7A 1ED8A 1AJAA 5C66A 5LIAA 3NKMA 2VQRA 5GRRA 4GTWA 5DLWA 3IGZB 3SZZA 2D1GA 1ALJA 5L0KA 2QZUA 3UN5A 1E1ZP 2G9YA 2W5WA 4LQYA 1ZEFA 4GTXA 1EW2A 3NKOA 4MHXA 3WAWA 1EI6A 2W8DA 4MIVA 5EGHA 2ZKTA 3UO0A 4NWXA 3TWZA 3WAYA 4KM4A 3B5QA 1URAA 3M8ZA 1ANJA 4FDIA 5GOVA 1O99A 1KH5A 3WAXA 4LRBA 3E2DA 5INHA 1O98A 1KHKA 1AJCA 2ANHA 2W8SA 1E3CP 4B56A 1N2LA 1K7HA 2W5QA 1Y7AA 4UOPA 3UN3A 1SHNA 3T02A 4KJGA 3MK2A 1KH9A 3NVLA 1N2KA 3TG0A 5IJQA 5L0EA 2GSOA 2W5SA 1AJBA 1SHQA 2GA3A 1URBA 2XR9A 3KD8A 4CXSA 4LRDA 1HQAA 4N7TA 5KXAA 1ALIA 3WBHA 1Y6VA 2RH6A 4UPLA 3LXQA 3M7VA 4LR9A 4UPIA 3UN2A 5IJSA 1ELXA 3CMRA 4QAXA 3ED4A 1KHLA 1AUKA 4UOOA 3WAVA 1ALKA 5EGEA 2GSNA 2IUCA 1EW8A 3MK0A 3M8YA 4UPHA 4KAYA 3SZYA 3OT9A 5L0BA 4CYRA 4ZG6A 5DLTA 3UNYA 1ZEBA 4MY4A 2W5TA 1ANIA 4KJDA 2X98A 1EJJA 3NKQA 5DLVA 1ED9A 2IFYA 3BDFA 4LR7A 1E33P 5LRMA 4ZG7A 1EQJA 3M8WA 3BDHA 4ZG9A 4LRAA 4CXKA 3IGYB 4ZGAA 1ZEDA 2W5RA 4GTZA 4FDJA 3BDGA 1HJKA 4UPKA 1E2SP 1P49A 2IUCB 4LR8A 3NKNA 3DPCA 5TJ3A 3IDDA 4TN0A 3NKPA 1ALHA 2W5VA 1ELYA 1HDHA 2XRGA 3MK1A 5AJ9A 3T01A 1FSUA 4GTYA 4LR2A 5LQQA 2GLQA 3A52A
chains in the Genus database with same CATH superfamily
2GSUA 4KAVA 5HRTA 1B8JA 3TX0A 4CYSA 4LRFA 4UORA 4YR1A 1KHNA 3BDGB 4NWJA 4CXUA 3T00A 1ELZA 3NKRA 5LRNA 1KHJA 4LRCA 3DYCA 4LREA 1AJDA 1EW9A 2W5XA 3Q3QA 1KH4A 5K4PA 1KH7A 1ED8A 1AJAA 5C66A 5LIAA 3NKMA 2VQRA 5GRRA 4GTWA 5DLWA 3IGZB 3SZZA 2D1GA 1ALJA 5L0KA 2QZUA 3UN5A 1E1ZP 2G9YA 2W5WA 4LQYA 1ZEFA 4GTXA 1EW2A 3NKOA 4MHXA 3WAWA 1EI6A 2W8DA 4MIVA 5EGHA 2ZKTA 3UO0A 4NWXA 3TWZA 3WAYA 4KM4A 3B5QA 1URAA 3M8ZA 1ANJA 4FDIA 5GOVA 1O99A 1KH5A 3WAXA 4LRBA 3E2DA 5INHA 1O98A 1KHKA 1AJCA 2ANHA 2W8SA 1E3CP 4B56A 1N2LA 1K7HA 2W5QA 1Y7AA 4UOPA 3UN3A 1SHNA 3T02A 4KJGA 3MK2A 1KH9A 3NVLA 1N2KA 3TG0A 5IJQA 5L0EA 2GSOA 2W5SA 1AJBA 1SHQA 2GA3A 1URBA 2XR9A 3KD8A 4CXSA 4LRDA 1HQAA 4N7TA 5KXAA 1ALIA 3WBHA 1Y6VA 2RH6A 4UPLA 3LXQA 3M7VA 4LR9A 4UPIA 3UN2A 5IJSA 1ELXA 3CMRA 4QAXA 3ED4A 1KHLA 1AUKA 4UOOA 3WAVA 1ALKA 5EGEA 2GSNA 2IUCA 1EW8A 3MK0A 3M8YA 4UPHA 4KAYA 3SZYA 3OT9A 5L0BA 4CYRA 4ZG6A 5DLTA 3UNYA 1ZEBA 4MY4A 2W5TA 1ANIA 4KJDA 2X98A 1EJJA 3NKQA 5DLVA 1ED9A 2IFYA 3BDFA 4LR7A 1E33P 5LRMA 4ZG7A 1EQJA 3M8WA 3BDHA 4ZG9A 4LRAA 4CXKA 3IGYB 4ZGAA 1ZEDA 2W5RA 4GTZA 4FDJA 3BDGA 1HJKA 4UPKA 1E2SP 1P49A 2IUCB 4LR8A 3NKNA 3DPCA 5TJ3A 3IDDA 4TN0A 3NKPA 1ALHA 2W5VA 1ELYA 1HDHA 2XRGA 3MK1A 5AJ9A 3T01A 1FSUA 4GTYA 4LR2A 5LQQA 2GLQA 3A52A
chains in the Genus database with same CATH topology
2GSUA 4KAVA 5HRTA 1B8JA 3TX0A 4CYSA 4LRFA 4UORA 4YR1A 1KHNA 3BDGB 4NWJA 4CXUA 3T00A 1ELZA 3NKRA 5LRNA 1KHJA 4LRCA 3DYCA 4LREA 1AJDA 1EW9A 2W5XA 3Q3QA 1KH4A 5K4PA 1KH7A 1ED8A 1AJAA 5C66A 5LIAA 3NKMA 2VQRA 5GRRA 4GTWA 5DLWA 3IGZB 3SZZA 2D1GA 1ALJA 5L0KA 2QZUA 3UN5A 1E1ZP 2G9YA 2W5WA 4LQYA 1ZEFA 4GTXA 1EW2A 3NKOA 4MHXA 3WAWA 1EI6A 2W8DA 4MIVA 5EGHA 2ZKTA 3UO0A 4NWXA 3TWZA 3WAYA 4KM4A 3B5QA 1URAA 3M8ZA 1ANJA 4FDIA 5GOVA 1O99A 1KH5A 3WAXA 4LRBA 3E2DA 5INHA 1O98A 1KHKA 1AJCA 2ANHA 2W8SA 1E3CP 4B56A 1N2LA 1K7HA 2W5QA 1Y7AA 4UOPA 3UN3A 1SHNA 3T02A 4KJGA 3MK2A 1KH9A 3NVLA 1N2KA 3TG0A 5IJQA 5L0EA 2GSOA 2W5SA 1AJBA 1SHQA 2GA3A 1URBA 2XR9A 3KD8A 4CXSA 4LRDA 1HQAA 4N7TA 5KXAA 1ALIA 3WBHA 1Y6VA 2RH6A 4UPLA 3LXQA 3M7VA 4LR9A 4UPIA 3UN2A 5IJSA 1ELXA 3CMRA 4QAXA 3ED4A 1KHLA 1AUKA 4UOOA 3WAVA 1ALKA 5EGEA 2GSNA 2IUCA 1EW8A 3MK0A 3M8YA 4UPHA 4KAYA 3SZYA 3OT9A 5L0BA 4CYRA 4ZG6A 5DLTA 3UNYA 1ZEBA 4MY4A 2W5TA 1ANIA 4KJDA 2X98A 1EJJA 3NKQA 5DLVA 1ED9A 2IFYA 3BDFA 4LR7A 1E33P 5LRMA 4ZG7A 1EQJA 3M8WA 3BDHA 4ZG9A 4LRAA 4CXKA 3IGYB 4ZGAA 1ZEDA 2W5RA 4GTZA 4FDJA 3BDGA 1HJKA 4UPKA 1E2SP 1P49A 2IUCB 4LR8A 3NKNA 3DPCA 5TJ3A 3IDDA 4TN0A 3NKPA 1ALHA 2W5VA 1ELYA 1HDHA 2XRGA 3MK1A 5AJ9A 3T01A 1FSUA 4GTYA 4LR2A 5LQQA 2GLQA 3A52A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GSU A;  4KAV A;  5HRT A;  1B8J A;  3TX0 A;  4CYS A;  4LRF A;  4UOR A;  4YR1 A;  1KHN A;  3BDG B;  4NWJ A;  4CXU A;  3T00 A;  1ELZ A;  3NKR A;  5LRN A;  1KHJ A;  4LRC A;  3DYC A;  4LRE A;  1AJD A;  1EW9 A;  2W5X A;  3Q3Q A;  1KH4 A;  5K4P A;  1KH7 A;  1ED8 A;  1AJA A;  5C66 A;  5LIA A;  3NKM A;  2VQR A;  5GRR A;  4GTW A;  5DLW A;  3IGZ B;  3SZZ A;  2D1G A;  1ALJ A;  5L0K A;  2QZU A;  3UN5 A;  1E1Z P;  2G9Y A;  2W5W A;  4LQY A;  1ZEF A;  4GTX A;  1EW2 A;  3NKO A;  4MHX A;  3WAW A;  1EI6 A;  2W8D A;  4MIV A;  5EGH A;  2ZKT A;  3UO0 A;  4NWX A;  3TWZ A;  3WAY A;  4KM4 A;  3B5Q A;  1URA A;  3M8Z A;  1ANJ A;  4FDI A;  5GOV A;  1O99 A;  1KH5 A;  3WAX A;  4LRB A;  3E2D A;  5INH A;  1O98 A;  1KHK A;  1AJC A;  2ANH A;  2W8S A;  1E3C P;  4B56 A;  1N2L A;  1K7H A;  2W5Q A;  1Y7A A;  4UOP A;  3UN3 A;  1SHN A;  3T02 A;  4KJG A;  3MK2 A;  1KH9 A;  3NVL A;  1N2K A;  3TG0 A;  5IJQ A;  5L0E A;  2GSO A;  2W5S A;  1AJB A;  1SHQ A;  2GA3 A;  1URB A;  2XR9 A;  3KD8 A;  4CXS A;  4LRD A;  1HQA A;  4N7T A;  5KXA A;  1ALI A;  3WBH A;  1Y6V A;  2RH6 A;  4UPL A;  3LXQ A;  3M7V A;  4LR9 A;  4UPI A;  3UN2 A;  5IJS A;  1ELX A;  3CMR A;  4QAX A;  3ED4 A;  1KHL A;  1AUK A;  4UOO A;  3WAV A;  1ALK A;  5EGE A;  2GSN A;  2IUC A;  1EW8 A;  3MK0 A;  3M8Y A;  4UPH A;  4KAY A;  3SZY A;  3OT9 A;  5L0B A;  4CYR A;  4ZG6 A;  5DLT A;  3UNY A;  1ZEB A;  4MY4 A;  2W5T A;  1ANI A;  4KJD A;  2X98 A;  1EJJ A;  3NKQ A;  5DLV A;  1ED9 A;  2IFY A;  3BDF A;  4LR7 A;  1E33 P;  5LRM A;  4ZG7 A;  1EQJ A;  3M8W A;  3BDH A;  4ZG9 A;  4LRA A;  4CXK A;  3IGY B;  4ZGA A;  1ZED A;  2W5R A;  4GTZ A;  4FDJ A;  3BDG A;  1HJK A;  4UPK A;  1E2S P;  1P49 A;  2IUC B;  4LR8 A;  3NKN A;  3DPC A;  5TJ3 A;  3IDD A;  4TN0 A;  3NKP A;  1ALH A;  2W5V A;  1ELY A;  1HDH A;  2XRG A;  3MK1 A;  5AJ9 A;  3T01 A;  1FSU A;  4GTY A;  4LR2 A;  5LQQ A;  2GLQ A;  3A52 A; 
#chains in the Genus database with same CATH topology
 2GSU A;  4KAV A;  5HRT A;  1B8J A;  3TX0 A;  4CYS A;  4LRF A;  4UOR A;  4YR1 A;  1KHN A;  3BDG B;  4NWJ A;  4CXU A;  3T00 A;  1ELZ A;  3NKR A;  5LRN A;  1KHJ A;  4LRC A;  3DYC A;  4LRE A;  1AJD A;  1EW9 A;  2W5X A;  3Q3Q A;  1KH4 A;  5K4P A;  1KH7 A;  1ED8 A;  1AJA A;  5C66 A;  5LIA A;  3NKM A;  2VQR A;  5GRR A;  4GTW A;  5DLW A;  3IGZ B;  3SZZ A;  2D1G A;  1ALJ A;  5L0K A;  2QZU A;  3UN5 A;  1E1Z P;  2G9Y A;  2W5W A;  4LQY A;  1ZEF A;  4GTX A;  1EW2 A;  3NKO A;  4MHX A;  3WAW A;  1EI6 A;  2W8D A;  4MIV A;  5EGH A;  2ZKT A;  3UO0 A;  4NWX A;  3TWZ A;  3WAY A;  4KM4 A;  3B5Q A;  1URA A;  3M8Z A;  1ANJ A;  4FDI A;  5GOV A;  1O99 A;  1KH5 A;  3WAX A;  4LRB A;  3E2D A;  5INH A;  1O98 A;  1KHK A;  1AJC A;  2ANH A;  2W8S A;  1E3C P;  4B56 A;  1N2L A;  1K7H A;  2W5Q A;  1Y7A A;  4UOP A;  3UN3 A;  1SHN A;  3T02 A;  4KJG A;  3MK2 A;  1KH9 A;  3NVL A;  1N2K A;  3TG0 A;  5IJQ A;  5L0E A;  2GSO A;  2W5S A;  1AJB A;  1SHQ A;  2GA3 A;  1URB A;  2XR9 A;  3KD8 A;  4CXS A;  4LRD A;  1HQA A;  4N7T A;  5KXA A;  1ALI A;  3WBH A;  1Y6V A;  2RH6 A;  4UPL A;  3LXQ A;  3M7V A;  4LR9 A;  4UPI A;  3UN2 A;  5IJS A;  1ELX A;  3CMR A;  4QAX A;  3ED4 A;  1KHL A;  1AUK A;  4UOO A;  3WAV A;  1ALK A;  5EGE A;  2GSN A;  2IUC A;  1EW8 A;  3MK0 A;  3M8Y A;  4UPH A;  4KAY A;  3SZY A;  3OT9 A;  5L0B A;  4CYR A;  4ZG6 A;  5DLT A;  3UNY A;  1ZEB A;  4MY4 A;  2W5T A;  1ANI A;  4KJD A;  2X98 A;  1EJJ A;  3NKQ A;  5DLV A;  1ED9 A;  2IFY A;  3BDF A;  4LR7 A;  1E33 P;  5LRM A;  4ZG7 A;  1EQJ A;  3M8W A;  3BDH A;  4ZG9 A;  4LRA A;  4CXK A;  3IGY B;  4ZGA A;  1ZED A;  2W5R A;  4GTZ A;  4FDJ A;  3BDG A;  1HJK A;  4UPK A;  1E2S P;  1P49 A;  2IUC B;  4LR8 A;  3NKN A;  3DPC A;  5TJ3 A;  3IDD A;  4TN0 A;  3NKP A;  1ALH A;  2W5V A;  1ELY A;  1HDH A;  2XRG A;  3MK1 A;  5AJ9 A;  3T01 A;  1FSU A;  4GTY A;  4LR2 A;  5LQQ A;  2GLQ A;  3A52 A; 
#chains in the Genus database with same CATH homology
 2GSU A;  4KAV A;  5HRT A;  1B8J A;  3TX0 A;  4CYS A;  4LRF A;  4UOR A;  4YR1 A;  1KHN A;  3BDG B;  4NWJ A;  4CXU A;  3T00 A;  1ELZ A;  3NKR A;  5LRN A;  1KHJ A;  4LRC A;  3DYC A;  4LRE A;  1AJD A;  1EW9 A;  2W5X A;  3Q3Q A;  1KH4 A;  5K4P A;  1KH7 A;  1ED8 A;  1AJA A;  5C66 A;  5LIA A;  3NKM A;  2VQR A;  5GRR A;  4GTW A;  5DLW A;  3IGZ B;  3SZZ A;  2D1G A;  1ALJ A;  5L0K A;  2QZU A;  3UN5 A;  1E1Z P;  2G9Y A;  2W5W A;  4LQY A;  1ZEF A;  4GTX A;  1EW2 A;  3NKO A;  4MHX A;  3WAW A;  1EI6 A;  2W8D A;  4MIV A;  5EGH A;  2ZKT A;  3UO0 A;  4NWX A;  3TWZ A;  3WAY A;  4KM4 A;  3B5Q A;  1URA A;  3M8Z A;  1ANJ A;  4FDI A;  5GOV A;  1O99 A;  1KH5 A;  3WAX A;  4LRB A;  3E2D A;  5INH A;  1O98 A;  1KHK A;  1AJC A;  2ANH A;  2W8S A;  1E3C P;  4B56 A;  1N2L A;  1K7H A;  2W5Q A;  1Y7A A;  4UOP A;  3UN3 A;  1SHN A;  3T02 A;  4KJG A;  3MK2 A;  1KH9 A;  3NVL A;  1N2K A;  3TG0 A;  5IJQ A;  5L0E A;  2GSO A;  2W5S A;  1AJB A;  1SHQ A;  2GA3 A;  1URB A;  2XR9 A;  3KD8 A;  4CXS A;  4LRD A;  1HQA A;  4N7T A;  5KXA A;  1ALI A;  3WBH A;  1Y6V A;  2RH6 A;  4UPL A;  3LXQ A;  3M7V A;  4LR9 A;  4UPI A;  3UN2 A;  5IJS A;  1ELX A;  3CMR A;  4QAX A;  3ED4 A;  1KHL A;  1AUK A;  4UOO A;  3WAV A;  1ALK A;  5EGE A;  2GSN A;  2IUC A;  1EW8 A;  3MK0 A;  3M8Y A;  4UPH A;  4KAY A;  3SZY A;  3OT9 A;  5L0B A;  4CYR A;  4ZG6 A;  5DLT A;  3UNY A;  1ZEB A;  4MY4 A;  2W5T A;  1ANI A;  4KJD A;  2X98 A;  1EJJ A;  3NKQ A;  5DLV A;  1ED9 A;  2IFY A;  3BDF A;  4LR7 A;  1E33 P;  5LRM A;  4ZG7 A;  1EQJ A;  3M8W A;  3BDH A;  4ZG9 A;  4LRA A;  4CXK A;  3IGY B;  4ZGA A;  1ZED A;  2W5R A;  4GTZ A;  4FDJ A;  3BDG A;  1HJK A;  4UPK A;  1E2S P;  1P49 A;  2IUC B;  4LR8 A;  3NKN A;  3DPC A;  5TJ3 A;  3IDD A;  4TN0 A;  3NKP A;  1ALH A;  2W5V A;  1ELY A;  1HDH A;  2XRG A;  3MK1 A;  5AJ9 A;  3T01 A;  1FSU A;  4GTY A;  4LR2 A;  5LQQ A;  2GLQ A;  3A52 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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