1OJVA

Decay accelerating factor (cd55): the structure of an intact human complement regulator.
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
254
structure length
254
Chain Sequence
MQDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Complement Regulation at the Molecular Level: The Structure of Decay-Accelerating Factor
pubmed doi rcsb
molecule tags Regulator of complement pathway
source organism Homo sapiens
molecule keywords COMPLEMENT DECAY-ACCELERATING FACTOR
total genus 41
structure length 254
sequence length 254
chains with identical sequence B
ec nomenclature
pdb deposition date 2003-07-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00084 Sushi Sushi repeat (SCR repeat)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1ojvA04
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1ojvA03
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1ojvA01
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1ojvA02
2ERJA 4A5WB 1C1ZA 3OXUD 4DJZA 3ERBA 3NFPI 1SS2A 3SW0X 2MCZA 2V8EA 2KRIA 2JGWA 1OK9A 3L89M 1HCCA 1TPMA 5JPMG 1H2PP 2XWBF 3GOVA 2LOJA 1Q3XA 3ZD1A 2G7IA 2IZ3A 3INBC 3OEDC 2BZMA 2WIIC 2O39C 1E88A 2IZ4A 4AYEA 1VVCA 2B5ID 3IU3I 1LY2A 1H04P 5HZPB 1HFIA 1H2QP 2JGXA 4FXGG 1QO6A 5HYPA 2RKYA 2W80A 3EJHA 4LOTA 4ZH1D 2XRBA 3R62A 1H03P 3TVJA 1OJVA 1QUBA 1GKGA 4F4OC 2RLPA 2JRAA 2RKZA 4AYDA 2YBYA 1OK1A 2CKUA 1FBRA 1GPZA 2EHFA 4JHSA 2XWJI 5HYTB 4KKDA 1MD8A 3KXVA 1E8BA 2UWNA 4MUCA 1GKNA 1CKLA 4LOSA 3T5OA 1QGBA 2YRAA 3ZRZA 4WJG2 1OK3A 3ZD2A 2CG7A 2KMSA 1ZJKA 2XQWC 1O9AA 1E5GA 3MQLA 1ELVA 2W81A 1OJWA 2RL0A 4ONTD 5I0QB 3IX0A 3OP8A 1G4GA 1SRZA 2MCYA 4B2SA 1UOTP 1TPGA 2QY0A 4J38B 3O8EB 1G4FA 4C16A 1NWVA 1PPQA 2A55A 3KZJA 3M7PA 2XRDA 1OK2A 4CSYA 1HFHA 1MD7A 1U5MA 5FO8C 1Z92B 3RJ3D 5HYUB 1VVDA 1GHQB 4PZ5A 2EC3A 1TPNA 4AYIA 4YNXA 4B2RA 2CG6A 4IGDA 2RLQA 3CALA 1OJYA 4AYMA 3GXEA 4K12A
chains in the Genus database with same CATH superfamily
2ERJA 4A5WB 3F6KA 2Y8SA 1C1ZA 3OXUD 5DN5A 4DJZA 3ERBA 3NFPI 3K3TA 1SS2A 3SW0X 2MCZA 2X2ZA 2V8EA 2KRIA 2JGWA 1OK9A 3L89M 1HCCA 1TPMA 5JPMG 1H2PP 2XWBF 3GOVA 4N7EA 2LOJA 1Q3XA 3ZD1A 2G7IA 2IZ3A 3INBC 3OEDC 2ZYCA 2BZMA 2WIIC 4BWCA 2O39C 1E88A 2IZ4A 4AYEA 1VVCA 3FGRA 2B5ID 3IU3I 1LY2A 1H04P 5HZPB 1HFIA 1H2QP 2JGXA 4FXGG 1QO6A 5HYPA 2RKYA 2W80A 3EJHA 4LOTA 4ZH1D 2XRBA 3R62A 1H03P 3NJAA 3TVJA 1OJVA 1QUBA 1GKGA 3ZLDA 3CI0J 4F4OC 2RLPA 2JRAA 2RKZA 4AYDA 2YBYA 1OK1A 1RLHA 2CKUA 4PO7A 1FBRA 1GPZA 3VWOA 2EHFA 4JHSA 2XWJI 5HYTB 4KKDA 1MD8A 3KXVA 1E8BA 2UWNA 3FGTA 4MUCA 1GKNA 1CKLA 4LOSA 3T5OA 1QGBA 2YRAA 3ZLEA 4WJG2 1OK3A 3ZD2A 3ZRZA 2CG7A 2KMSA 1ZJKA 2XQWC 1O9AA 1E5GA 3MQLA 1ELVA 2W81A 1OJWA 2RL0A 2I2LA 4ONTD 3IX0A 5I0QB 3OP8A 1G4GA 1SRZA 2MCYA 4YIZA 4B2SA 1UOTP 1TPGA 2QY0A 4J38B 4MSLA 3O8EB 1G4FA 4C16A 1NWVA 1PPQA 2A55A 3KZJA 3M7PA 2XRDA 1OK2A 4CSYA 1HFHA 1MD7A 2Y8TA 5DN4A 2Y8RA 1U5MA 5FO8C 1Z92B 3RJ3D 3WSXA 5HYUB 1VVDA 1GHQB 4PZ5A 4APLA 2EC3A 3WSYA 1TPNA 4AYIA 4YNXA 4B2RA 2CG6A 4IGDA 2RLQA 3CALA 1OJYA 4AYMA 3GXEA 4K12A
chains in the Genus database with same CATH topology
2ERJA 4A5WB 1C1ZA 3OXUD 4DJZA 3ERBA 3NFPI 1SS2A 3SW0X 2MCZA 2V8EA 2KRIA 2JGWA 1OK9A 3L89M 1HCCA 1TPMA 5JPMG 1H2PP 2XWBF 3GOVA 2LOJA 1Q3XA 3ZD1A 2G7IA 2IZ3A 3INBC 3OEDC 2BZMA 2WIIC 2O39C 1E88A 2IZ4A 4AYEA 1VVCA 2B5ID 3IU3I 1LY2A 1H04P 5HZPB 1HFIA 1H2QP 2JGXA 4FXGG 1QO6A 5HYPA 2RKYA 2W80A 3EJHA 4LOTA 4ZH1D 2XRBA 3R62A 1H03P 3TVJA 1OJVA 1QUBA 1GKGA 4F4OC 2RLPA 2JRAA 2RKZA 4AYDA 2YBYA 1OK1A 2CKUA 1FBRA 1GPZA 2EHFA 4JHSA 2XWJI 5HYTB 4KKDA 1MD8A 3KXVA 1E8BA 2UWNA 4MUCA 1GKNA 1CKLA 4LOSA 3T5OA 1QGBA 2YRAA 3ZRZA 4WJG2 1OK3A 3ZD2A 2CG7A 2KMSA 1ZJKA 2XQWC 1O9AA 1E5GA 3MQLA 1ELVA 2W81A 1OJWA 2RL0A 4ONTD 5I0QB 3IX0A 3OP8A 1G4GA 1SRZA 2MCYA 4B2SA 1UOTP 1TPGA 2QY0A 4J38B 3O8EB 1G4FA 4C16A 1NWVA 1PPQA 2A55A 3KZJA 3M7PA 2XRDA 1OK2A 4CSYA 1HFHA 1MD7A 1U5MA 5FO8C 1Z92B 3RJ3D 5HYUB 1VVDA 1GHQB 4PZ5A 2EC3A 1TPNA 4AYIA 4YNXA 4B2RA 2CG6A 4IGDA 2RLQA 3CALA 1OJYA 4AYMA 3GXEA 4K12A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ERJ A;  4A5W B;  1C1Z A;  3OXU D;  4DJZ A;  3ERB A;  3NFP I;  1SS2 A;  3SW0 X;  2MCZ A;  2V8E A;  2KRI A;  2JGW A;  1OK9 A;  3L89 M;  1HCC A;  1TPM A;  5JPM G;  1H2P P;  2XWB F;  3GOV A;  2LOJ A;  1Q3X A;  3ZD1 A;  2G7I A;  2IZ3 A;  3INB C;  3OED C;  2BZM A;  2WII C;  2O39 C;  1E88 A;  2IZ4 A;  4AYE A;  1VVC A;  2B5I D;  3IU3 I;  1LY2 A;  1H04 P;  5HZP B;  1HFI A;  1H2Q P;  2JGX A;  4FXG G;  1QO6 A;  5HYP A;  2RKY A;  2W80 A;  3EJH A;  4LOT A;  4ZH1 D;  2XRB A;  3R62 A;  1H03 P;  3TVJ A;  1OJV A;  1QUB A;  1GKG A;  4F4O C;  2RLP A;  2JRA A;  2RKZ A;  4AYD A;  2YBY A;  1OK1 A;  2CKU A;  1FBR A;  1GPZ A;  2EHF A;  4JHS A;  2XWJ I;  5HYT B;  4KKD A;  1MD8 A;  3KXV A;  1E8B A;  2UWN A;  4MUC A;  1GKN A;  1CKL A;  4LOS A;  3T5O A;  1QGB A;  2YRA A;  3ZRZ A;  4WJG 2;  1OK3 A;  3ZD2 A;  2CG7 A;  2KMS A;  1ZJK A;  2XQW C;  1O9A A;  1E5G A;  3MQL A;  1ELV A;  2W81 A;  1OJW A;  2RL0 A;  4ONT D;  5I0Q B;  3IX0 A;  3OP8 A;  1G4G A;  1SRZ A;  2MCY A;  4B2S A;  1UOT P;  1TPG A;  2QY0 A;  4J38 B;  3O8E B;  1G4F A;  4C16 A;  1NWV A;  1PPQ A;  2A55 A;  3KZJ A;  3M7P A;  2XRD A;  1OK2 A;  4CSY A;  1HFH A;  1MD7 A;  1U5M A;  5FO8 C;  1Z92 B;  3RJ3 D;  5HYU B;  1VVD A;  1GHQ B;  4PZ5 A;  2EC3 A;  1TPN A;  4AYI A;  4YNX A;  4B2R A;  2CG6 A;  4IGD A;  2RLQ A;  3CAL A;  1OJY A;  4AYM A;  3GXE A;  4K12 A; 
#chains in the Genus database with same CATH topology
 2ERJ A;  4A5W B;  3F6K A;  2Y8S A;  1C1Z A;  3OXU D;  5DN5 A;  4DJZ A;  3ERB A;  3NFP I;  3K3T A;  1SS2 A;  3SW0 X;  2MCZ A;  2X2Z A;  2V8E A;  2KRI A;  2JGW A;  1OK9 A;  3L89 M;  1HCC A;  1TPM A;  5JPM G;  1H2P P;  2XWB F;  3GOV A;  4N7E A;  2LOJ A;  1Q3X A;  3ZD1 A;  2G7I A;  2IZ3 A;  3INB C;  3OED C;  2ZYC A;  2BZM A;  2WII C;  4BWC A;  2O39 C;  1E88 A;  2IZ4 A;  4AYE A;  1VVC A;  3FGR A;  2B5I D;  3IU3 I;  1LY2 A;  1H04 P;  5HZP B;  1HFI A;  1H2Q P;  2JGX A;  4FXG G;  1QO6 A;  5HYP A;  2RKY A;  2W80 A;  3EJH A;  4LOT A;  4ZH1 D;  2XRB A;  3R62 A;  1H03 P;  3NJA A;  3TVJ A;  1OJV A;  1QUB A;  1GKG A;  3ZLD A;  3CI0 J;  4F4O C;  2RLP A;  2JRA A;  2RKZ A;  4AYD A;  2YBY A;  1OK1 A;  1RLH A;  2CKU A;  4PO7 A;  1FBR A;  1GPZ A;  3VWO A;  2EHF A;  4JHS A;  2XWJ I;  5HYT B;  4KKD A;  1MD8 A;  3KXV A;  1E8B A;  2UWN A;  3FGT A;  4MUC A;  1GKN A;  1CKL A;  4LOS A;  3T5O A;  1QGB A;  2YRA A;  3ZLE A;  4WJG 2;  1OK3 A;  3ZD2 A;  3ZRZ A;  2CG7 A;  2KMS A;  1ZJK A;  2XQW C;  1O9A A;  1E5G A;  3MQL A;  1ELV A;  2W81 A;  1OJW A;  2RL0 A;  2I2L A;  4ONT D;  3IX0 A;  5I0Q B;  3OP8 A;  1G4G A;  1SRZ A;  2MCY A;  4YIZ A;  4B2S A;  1UOT P;  1TPG A;  2QY0 A;  4J38 B;  4MSL A;  3O8E B;  1G4F A;  4C16 A;  1NWV A;  1PPQ A;  2A55 A;  3KZJ A;  3M7P A;  2XRD A;  1OK2 A;  4CSY A;  1HFH A;  1MD7 A;  2Y8T A;  5DN4 A;  2Y8R A;  1U5M A;  5FO8 C;  1Z92 B;  3RJ3 D;  3WSX A;  5HYU B;  1VVD A;  1GHQ B;  4PZ5 A;  4APL A;  2EC3 A;  3WSY A;  1TPN A;  4AYI A;  4YNX A;  4B2R A;  2CG6 A;  4IGD A;  2RLQ A;  3CAL A;  1OJY A;  4AYM A;  3GXE A;  4K12 A; 
#chains in the Genus database with same CATH homology
 2ERJ A;  4A5W B;  1C1Z A;  3OXU D;  4DJZ A;  3ERB A;  3NFP I;  1SS2 A;  3SW0 X;  2MCZ A;  2V8E A;  2KRI A;  2JGW A;  1OK9 A;  3L89 M;  1HCC A;  1TPM A;  5JPM G;  1H2P P;  2XWB F;  3GOV A;  2LOJ A;  1Q3X A;  3ZD1 A;  2G7I A;  2IZ3 A;  3INB C;  3OED C;  2BZM A;  2WII C;  2O39 C;  1E88 A;  2IZ4 A;  4AYE A;  1VVC A;  2B5I D;  3IU3 I;  1LY2 A;  1H04 P;  5HZP B;  1HFI A;  1H2Q P;  2JGX A;  4FXG G;  1QO6 A;  5HYP A;  2RKY A;  2W80 A;  3EJH A;  4LOT A;  4ZH1 D;  2XRB A;  3R62 A;  1H03 P;  3TVJ A;  1OJV A;  1QUB A;  1GKG A;  4F4O C;  2RLP A;  2JRA A;  2RKZ A;  4AYD A;  2YBY A;  1OK1 A;  2CKU A;  1FBR A;  1GPZ A;  2EHF A;  4JHS A;  2XWJ I;  5HYT B;  4KKD A;  1MD8 A;  3KXV A;  1E8B A;  2UWN A;  4MUC A;  1GKN A;  1CKL A;  4LOS A;  3T5O A;  1QGB A;  2YRA A;  3ZRZ A;  4WJG 2;  1OK3 A;  3ZD2 A;  2CG7 A;  2KMS A;  1ZJK A;  2XQW C;  1O9A A;  1E5G A;  3MQL A;  1ELV A;  2W81 A;  1OJW A;  2RL0 A;  4ONT D;  5I0Q B;  3IX0 A;  3OP8 A;  1G4G A;  1SRZ A;  2MCY A;  4B2S A;  1UOT P;  1TPG A;  2QY0 A;  4J38 B;  3O8E B;  1G4F A;  4C16 A;  1NWV A;  1PPQ A;  2A55 A;  3KZJ A;  3M7P A;  2XRD A;  1OK2 A;  4CSY A;  1HFH A;  1MD7 A;  1U5M A;  5FO8 C;  1Z92 B;  3RJ3 D;  5HYU B;  1VVD A;  1GHQ B;  4PZ5 A;  2EC3 A;  1TPN A;  4AYI A;  4YNX A;  4B2R A;  2CG6 A;  4IGD A;  2RLQ A;  3CAL A;  1OJY A;  4AYM A;  3GXE A;  4K12 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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