1OK1A

Decay accelerating factor (cd55) : the structure of an intact human complement regulator.
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
254
structure length
254
Chain Sequence
MQDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Complement Regulation at the Molecular Level: The Structure of Decay-Accelerating Factor
pubmed doi rcsb
molecule tags Regulator of complement pathway
source organism Homo sapiens
molecule keywords COMPLEMENT DECAY-ACCELERATING FACTOR
total genus 38
structure length 254
sequence length 254
chains with identical sequence B
ec nomenclature
pdb deposition date 2003-07-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00084 Sushi Sushi repeat (SCR repeat)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1ok1A04
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1ok1A03
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1ok1A01
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1ok1A02
4PZ5A 4YNXA 4AYEA 5HYUB 4J38B 1TPMA 1Z92B 1FBRA 4B2RA 3ZRZA 4JHSA 2MCZA 2YRAA 1MD8A 2KMSA 4ZH1D 1TPGA 2W80A 1SS2A 1QO6A 3OXUD 1E8BA 1ELVA 2B5ID 2XRDA 3GOVA 4MUCA 1UOTP 1QUBA 4KKDA 1OJVA 2MCYA 1NWVA 5HYTB 1G4GA 2IZ4A 4FXGG 1OJWA 2UWNA 3RJ3D 1E88A 2RL0A 2RKYA 2YBYA 2JRAA 1LY2A 2XQWC 4B2SA 3IX0A 3OEDC 3SW0X 3ZD2A 4C16A 4A5WB 4DJZA 2WIIC 1Q3XA 3NFPI 4WJG2 1OK9A 4ONTD 3OP8A 1GKGA 5FO8C 1OK3A 2CKUA 3KZJA 2LOJA 2RLQA 2RLPA 1VVCA 1OJYA 2XWBF 1TPNA 3IU3I 3GXEA 4CSYA 1H2PP 1SRZA 1HFHA 3TVJA 2O39C 2JGXA 2ERJA 1H2QP 3L89M 2CG7A 4F4OC 3CALA 3R62A 4LOSA 3MQLA 5HYPA 2BZMA 2CG6A 2QY0A 3KXVA 2JGWA 1U5MA 1GHQB 2XRBA 1H03P 1G4FA 2G7IA 3INBC 1GPZA 1CKLA 3O8EB 3ERBA 4AYDA 5I0QB 5JPMG 2EHFA 1QGBA 1GKNA 1E5GA 3EJHA 1PPQA 3ZD1A 1HCCA 4AYIA 2KRIA 4AYMA 2W81A 1VVDA 1MD7A 1OK2A 2EC3A 1O9AA 2RKZA 1H04P 1ZJKA 3T5OA 2A55A 1C1ZA 1HFIA 2V8EA 4K12A 5HZPB 2IZ3A 2XWJI 3M7PA 4IGDA 4LOTA 1OK1A
chains in the Genus database with same CATH superfamily
4PZ5A 3ZLEA 4YNXA 4AYEA 5HYUB 4J38B 1TPMA 1Z92B 1FBRA 4B2RA 3ZRZA 3F6KA 4JHSA 2MCZA 2YRAA 4BWCA 2Y8SA 1MD8A 2KMSA 4ZH1D 1TPGA 2W80A 1SS2A 2Y8TA 1QO6A 3OXUD 1E8BA 1ELVA 2B5ID 5DN5A 2XRDA 4APLA 3GOVA 4MUCA 1UOTP 1QUBA 4KKDA 1OJVA 2MCYA 1NWVA 5HYTB 2ZYCA 1G4GA 2IZ4A 4FXGG 1OJWA 2UWNA 3RJ3D 1E88A 2RL0A 2RKYA 2YBYA 2JRAA 1LY2A 2XQWC 3WSYA 4B2SA 3IX0A 3OEDC 3SW0X 2I2LA 4MSLA 3ZD2A 4C16A 4A5WB 4DJZA 2WIIC 1Q3XA 3NFPI 4WJG2 3K3TA 1OK9A 4ONTD 3OP8A 1GKGA 5FO8C 1OK3A 3NJAA 2CKUA 3KZJA 2LOJA 3CI0J 2RLQA 2RLPA 1VVCA 1OJYA 2XWBF 3VWOA 1TPNA 3IU3I 3ZLDA 3GXEA 3WSXA 4CSYA 1H2PP 1SRZA 1HFHA 3TVJA 4N7EA 2O39C 2JGXA 2ERJA 1H2QP 3L89M 2CG7A 2Y8RA 4F4OC 3CALA 3R62A 4LOSA 3MQLA 5HYPA 2BZMA 2CG6A 2QY0A 3KXVA 2JGWA 1U5MA 1GHQB 2XRBA 1H03P 1G4FA 2G7IA 3INBC 4PO7A 1GPZA 1CKLA 3O8EB 3ERBA 4AYDA 5I0QB 5JPMG 4YIZA 2EHFA 1QGBA 1GKNA 1E5GA 3EJHA 1PPQA 3ZD1A 1HCCA 4AYIA 2KRIA 4AYMA 2W81A 1VVDA 1MD7A 3FGRA 1OK2A 2X2ZA 2EC3A 1RLHA 1O9AA 3FGTA 2RKZA 5DN4A 1H04P 1ZJKA 3T5OA 2A55A 1C1ZA 1HFIA 2V8EA 4K12A 5HZPB 2IZ3A 2XWJI 3M7PA 4IGDA 4LOTA 1OK1A
chains in the Genus database with same CATH topology
4PZ5A 4YNXA 4AYEA 5HYUB 4J38B 1TPMA 1Z92B 1FBRA 4B2RA 3ZRZA 4JHSA 2MCZA 2YRAA 1MD8A 2KMSA 4ZH1D 1TPGA 2W80A 1SS2A 1QO6A 3OXUD 1E8BA 1ELVA 2B5ID 2XRDA 3GOVA 4MUCA 1UOTP 1QUBA 4KKDA 1OJVA 2MCYA 1NWVA 5HYTB 1G4GA 2IZ4A 4FXGG 1OJWA 2UWNA 3RJ3D 1E88A 2RL0A 2RKYA 2YBYA 2JRAA 1LY2A 2XQWC 4B2SA 3IX0A 3OEDC 3SW0X 3ZD2A 4C16A 4A5WB 4DJZA 2WIIC 1Q3XA 3NFPI 4WJG2 1OK9A 4ONTD 3OP8A 1GKGA 5FO8C 1OK3A 2CKUA 3KZJA 2LOJA 2RLQA 2RLPA 1VVCA 1OJYA 2XWBF 1TPNA 3IU3I 3GXEA 4CSYA 1H2PP 1SRZA 1HFHA 3TVJA 2O39C 2JGXA 2ERJA 1H2QP 3L89M 2CG7A 4F4OC 3CALA 3R62A 4LOSA 3MQLA 5HYPA 2BZMA 2CG6A 2QY0A 3KXVA 2JGWA 1U5MA 1GHQB 2XRBA 1H03P 1G4FA 2G7IA 3INBC 1GPZA 1CKLA 3O8EB 3ERBA 4AYDA 5I0QB 5JPMG 2EHFA 1QGBA 1GKNA 1E5GA 3EJHA 1PPQA 3ZD1A 1HCCA 4AYIA 2KRIA 4AYMA 2W81A 1VVDA 1MD7A 1OK2A 2EC3A 1O9AA 2RKZA 1H04P 1ZJKA 3T5OA 2A55A 1C1ZA 1HFIA 2V8EA 4K12A 5HZPB 2IZ3A 2XWJI 3M7PA 4IGDA 4LOTA 1OK1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4PZ5 A;  4YNX A;  4AYE A;  5HYU B;  4J38 B;  1TPM A;  1Z92 B;  1FBR A;  4B2R A;  3ZRZ A;  4JHS A;  2MCZ A;  2YRA A;  1MD8 A;  2KMS A;  4ZH1 D;  1TPG A;  2W80 A;  1SS2 A;  1QO6 A;  3OXU D;  1E8B A;  1ELV A;  2B5I D;  2XRD A;  3GOV A;  4MUC A;  1UOT P;  1QUB A;  4KKD A;  1OJV A;  2MCY A;  1NWV A;  5HYT B;  1G4G A;  2IZ4 A;  4FXG G;  1OJW A;  2UWN A;  3RJ3 D;  1E88 A;  2RL0 A;  2RKY A;  2YBY A;  2JRA A;  1LY2 A;  2XQW C;  4B2S A;  3IX0 A;  3OED C;  3SW0 X;  3ZD2 A;  4C16 A;  4A5W B;  4DJZ A;  2WII C;  1Q3X A;  3NFP I;  4WJG 2;  1OK9 A;  4ONT D;  3OP8 A;  1GKG A;  5FO8 C;  1OK3 A;  2CKU A;  3KZJ A;  2LOJ A;  2RLQ A;  2RLP A;  1VVC A;  1OJY A;  2XWB F;  1TPN A;  3IU3 I;  3GXE A;  4CSY A;  1H2P P;  1SRZ A;  1HFH A;  3TVJ A;  2O39 C;  2JGX A;  2ERJ A;  1H2Q P;  3L89 M;  2CG7 A;  4F4O C;  3CAL A;  3R62 A;  4LOS A;  3MQL A;  5HYP A;  2BZM A;  2CG6 A;  2QY0 A;  3KXV A;  2JGW A;  1U5M A;  1GHQ B;  2XRB A;  1H03 P;  1G4F A;  2G7I A;  3INB C;  1GPZ A;  1CKL A;  3O8E B;  3ERB A;  4AYD A;  5I0Q B;  5JPM G;  2EHF A;  1QGB A;  1GKN A;  1E5G A;  3EJH A;  1PPQ A;  3ZD1 A;  1HCC A;  4AYI A;  2KRI A;  4AYM A;  2W81 A;  1VVD A;  1MD7 A;  1OK2 A;  2EC3 A;  1O9A A;  2RKZ A;  1H04 P;  1ZJK A;  3T5O A;  2A55 A;  1C1Z A;  1HFI A;  2V8E A;  4K12 A;  5HZP B;  2IZ3 A;  2XWJ I;  3M7P A;  4IGD A;  4LOT A;  1OK1 A; 
#chains in the Genus database with same CATH topology
 4PZ5 A;  3ZLE A;  4YNX A;  4AYE A;  5HYU B;  4J38 B;  1TPM A;  1Z92 B;  1FBR A;  4B2R A;  3ZRZ A;  3F6K A;  4JHS A;  2MCZ A;  2YRA A;  4BWC A;  2Y8S A;  1MD8 A;  2KMS A;  4ZH1 D;  1TPG A;  2W80 A;  1SS2 A;  2Y8T A;  1QO6 A;  3OXU D;  1E8B A;  1ELV A;  2B5I D;  5DN5 A;  2XRD A;  4APL A;  3GOV A;  4MUC A;  1UOT P;  1QUB A;  4KKD A;  1OJV A;  2MCY A;  1NWV A;  5HYT B;  2ZYC A;  1G4G A;  2IZ4 A;  4FXG G;  1OJW A;  2UWN A;  3RJ3 D;  1E88 A;  2RL0 A;  2RKY A;  2YBY A;  2JRA A;  1LY2 A;  2XQW C;  3WSY A;  4B2S A;  3IX0 A;  3OED C;  3SW0 X;  2I2L A;  4MSL A;  3ZD2 A;  4C16 A;  4A5W B;  4DJZ A;  2WII C;  1Q3X A;  3NFP I;  4WJG 2;  3K3T A;  1OK9 A;  4ONT D;  3OP8 A;  1GKG A;  5FO8 C;  1OK3 A;  3NJA A;  2CKU A;  3KZJ A;  2LOJ A;  3CI0 J;  2RLQ A;  2RLP A;  1VVC A;  1OJY A;  2XWB F;  3VWO A;  1TPN A;  3IU3 I;  3ZLD A;  3GXE A;  3WSX A;  4CSY A;  1H2P P;  1SRZ A;  1HFH A;  3TVJ A;  4N7E A;  2O39 C;  2JGX A;  2ERJ A;  1H2Q P;  3L89 M;  2CG7 A;  2Y8R A;  4F4O C;  3CAL A;  3R62 A;  4LOS A;  3MQL A;  5HYP A;  2BZM A;  2CG6 A;  2QY0 A;  3KXV A;  2JGW A;  1U5M A;  1GHQ B;  2XRB A;  1H03 P;  1G4F A;  2G7I A;  3INB C;  4PO7 A;  1GPZ A;  1CKL A;  3O8E B;  3ERB A;  4AYD A;  5I0Q B;  5JPM G;  4YIZ A;  2EHF A;  1QGB A;  1GKN A;  1E5G A;  3EJH A;  1PPQ A;  3ZD1 A;  1HCC A;  4AYI A;  2KRI A;  4AYM A;  2W81 A;  1VVD A;  1MD7 A;  3FGR A;  1OK2 A;  2X2Z A;  2EC3 A;  1RLH A;  1O9A A;  3FGT A;  2RKZ A;  5DN4 A;  1H04 P;  1ZJK A;  3T5O A;  2A55 A;  1C1Z A;  1HFI A;  2V8E A;  4K12 A;  5HZP B;  2IZ3 A;  2XWJ I;  3M7P A;  4IGD A;  4LOT A;  1OK1 A; 
#chains in the Genus database with same CATH homology
 4PZ5 A;  4YNX A;  4AYE A;  5HYU B;  4J38 B;  1TPM A;  1Z92 B;  1FBR A;  4B2R A;  3ZRZ A;  4JHS A;  2MCZ A;  2YRA A;  1MD8 A;  2KMS A;  4ZH1 D;  1TPG A;  2W80 A;  1SS2 A;  1QO6 A;  3OXU D;  1E8B A;  1ELV A;  2B5I D;  2XRD A;  3GOV A;  4MUC A;  1UOT P;  1QUB A;  4KKD A;  1OJV A;  2MCY A;  1NWV A;  5HYT B;  1G4G A;  2IZ4 A;  4FXG G;  1OJW A;  2UWN A;  3RJ3 D;  1E88 A;  2RL0 A;  2RKY A;  2YBY A;  2JRA A;  1LY2 A;  2XQW C;  4B2S A;  3IX0 A;  3OED C;  3SW0 X;  3ZD2 A;  4C16 A;  4A5W B;  4DJZ A;  2WII C;  1Q3X A;  3NFP I;  4WJG 2;  1OK9 A;  4ONT D;  3OP8 A;  1GKG A;  5FO8 C;  1OK3 A;  2CKU A;  3KZJ A;  2LOJ A;  2RLQ A;  2RLP A;  1VVC A;  1OJY A;  2XWB F;  1TPN A;  3IU3 I;  3GXE A;  4CSY A;  1H2P P;  1SRZ A;  1HFH A;  3TVJ A;  2O39 C;  2JGX A;  2ERJ A;  1H2Q P;  3L89 M;  2CG7 A;  4F4O C;  3CAL A;  3R62 A;  4LOS A;  3MQL A;  5HYP A;  2BZM A;  2CG6 A;  2QY0 A;  3KXV A;  2JGW A;  1U5M A;  1GHQ B;  2XRB A;  1H03 P;  1G4F A;  2G7I A;  3INB C;  1GPZ A;  1CKL A;  3O8E B;  3ERB A;  4AYD A;  5I0Q B;  5JPM G;  2EHF A;  1QGB A;  1GKN A;  1E5G A;  3EJH A;  1PPQ A;  3ZD1 A;  1HCC A;  4AYI A;  2KRI A;  4AYM A;  2W81 A;  1VVD A;  1MD7 A;  1OK2 A;  2EC3 A;  1O9A A;  2RKZ A;  1H04 P;  1ZJK A;  3T5O A;  2A55 A;  1C1Z A;  1HFI A;  2V8E A;  4K12 A;  5HZP B;  2IZ3 A;  2XWJ I;  3M7P A;  4IGD A;  4LOT A;  1OK1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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