1OK2A

Decay accelerating factor (cd55): the structure of an intact human complement regulator.
Total Genus 35
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
254
structure length
254
Chain Sequence
MQDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGC
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Complement Regulation at the Molecular Level: The Structure of Decay-Accelerating Factor
pubmed doi rcsb
molecule tags Regulator of complement pathway
source organism Homo sapiens
molecule keywords COMPLEMENT DECAY-ACCELERATING FACTOR
total genus 35
structure length 254
sequence length 254
chains with identical sequence B
ec nomenclature
pdb deposition date 2003-07-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00084 Sushi Sushi repeat (SCR repeat)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1ok2A04
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1ok2A03
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1ok2A01
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1ok2A02
1E5GA 4AYDA 4B2SA 3OXUD 2RKZA 4AYEA 4A5WB 4ZH1D 1OJYA 2CG7A 2XWJI 2KRIA 4J38B 2BZMA 4FXGG 2RKYA 2JGXA 3M7PA 1MD7A 3INBC 4KKDA 2EC3A 2QY0A 1PPQA 5I0QB 5FO8C 5JPMG 2MCZA 1HCCA 3T5OA 5HYUB 1CKLA 2MCYA 3ZD2A 2B5ID 2JRAA 1GPZA 2YBYA 3OEDC 1H04P 1SRZA 5HYPA 3ZRZA 1OK1A 1TPGA 4LOSA 1E88A 1G4FA 2IZ4A 2W80A 2UWNA 1UOTP 3OP8A 2XRDA 4PZ5A 3MQLA 4C16A 3KXVA 3L89M 2KMSA 4B2RA 2A55A 1E8BA 1LY2A 3CALA 4YNXA 2CKUA 1ELVA 2V8EA 2CG6A 2XWBF 4MUCA 1H2PP 4CSYA 2JGWA 1C1ZA 1QUBA 1GHQB 4AYMA 3EJHA 3IX0A 4IGDA 2WIIC 2O39C 2RL0A 1Q3XA 1OK9A 1NWVA 3NFPI 2XQWC 4ONTD 2ERJA 3ZD1A 4F4OC 4LOTA 1OK2A 3TVJA 1MD8A 1VVDA 3ERBA 2IZ3A 1G4GA 5HYTB 1SS2A 1O9AA 4AYIA 2RLPA 1QO6A 2W81A 2XRBA 2LOJA 1H03P 1ZJKA 4JHSA 2YRAA 1OK3A 1FBRA 3IU3I 1HFHA 1U5MA 1H2QP 3RJ3D 5HZPB 4K12A 1HFIA 4DJZA 3O8EB 1OJWA 4WJG2 1OJVA 3GXEA 3R62A 3KZJA 1GKNA 3SW0X 1VVCA 2EHFA 1GKGA 1TPMA 1Z92B 1TPNA 3GOVA 2G7IA 2RLQA 1QGBA
chains in the Genus database with same CATH superfamily
1E5GA 4AYDA 4PO7A 4YIZA 4B2SA 3OXUD 2RKZA 4AYEA 4A5WB 4ZH1D 4N7EA 1OJYA 2CG7A 2XWJI 2KRIA 4J38B 2I2LA 2BZMA 4FXGG 2RKYA 2JGXA 3M7PA 1MD7A 3INBC 4KKDA 2EC3A 3F6KA 2QY0A 1PPQA 5I0QB 5FO8C 5JPMG 2MCZA 1HCCA 3T5OA 5HYUB 1CKLA 2MCYA 3ZD2A 2B5ID 2JRAA 1GPZA 4BWCA 2YBYA 3OEDC 1H04P 1SRZA 5HYPA 3ZRZA 2X2ZA 2Y8RA 1OK1A 1TPGA 4LOSA 1E88A 3ZLEA 1G4FA 2IZ4A 2W80A 2UWNA 1UOTP 3OP8A 2XRDA 3NJAA 4PZ5A 3MQLA 4C16A 3KXVA 3L89M 3K3TA 2KMSA 4B2RA 2A55A 1E8BA 2ZYCA 1RLHA 3WSXA 1LY2A 3CALA 4YNXA 3ZLDA 2CKUA 1ELVA 2V8EA 2CG6A 4MSLA 2XWBF 4MUCA 1H2PP 4CSYA 2JGWA 3WSYA 1C1ZA 1QUBA 1GHQB 2Y8TA 4AYMA 3EJHA 3IX0A 2Y8SA 4IGDA 2WIIC 2O39C 2RL0A 1Q3XA 1OK9A 1NWVA 3NFPI 2XQWC 4ONTD 2ERJA 3CI0J 3ZD1A 4F4OC 4LOTA 1OK2A 5DN4A 3TVJA 5DN5A 1MD8A 3FGRA 1VVDA 3ERBA 2IZ3A 3FGTA 1G4GA 5HYTB 1SS2A 1O9AA 4AYIA 4APLA 2RLPA 1QO6A 2W81A 2XRBA 2LOJA 1H03P 1ZJKA 4JHSA 2YRAA 1OK3A 1FBRA 3VWOA 3IU3I 1HFHA 1U5MA 1H2QP 3RJ3D 5HZPB 4K12A 1HFIA 4DJZA 3O8EB 1OJWA 4WJG2 1OJVA 3GXEA 3R62A 3KZJA 1GKNA 3SW0X 1VVCA 2EHFA 1GKGA 1TPMA 1Z92B 1TPNA 3GOVA 2G7IA 2RLQA 1QGBA
chains in the Genus database with same CATH topology
1E5GA 4AYDA 4B2SA 3OXUD 2RKZA 4AYEA 4A5WB 4ZH1D 1OJYA 2CG7A 2XWJI 2KRIA 4J38B 2BZMA 4FXGG 2RKYA 2JGXA 3M7PA 1MD7A 3INBC 4KKDA 2EC3A 2QY0A 1PPQA 5I0QB 5FO8C 5JPMG 2MCZA 1HCCA 3T5OA 5HYUB 1CKLA 2MCYA 3ZD2A 2B5ID 2JRAA 1GPZA 2YBYA 3OEDC 1H04P 1SRZA 5HYPA 3ZRZA 1OK1A 1TPGA 4LOSA 1E88A 1G4FA 2IZ4A 2W80A 2UWNA 1UOTP 3OP8A 2XRDA 4PZ5A 3MQLA 4C16A 3KXVA 3L89M 2KMSA 4B2RA 2A55A 1E8BA 1LY2A 3CALA 4YNXA 2CKUA 1ELVA 2V8EA 2CG6A 2XWBF 4MUCA 1H2PP 4CSYA 2JGWA 1C1ZA 1QUBA 1GHQB 4AYMA 3EJHA 3IX0A 4IGDA 2WIIC 2O39C 2RL0A 1Q3XA 1OK9A 1NWVA 3NFPI 2XQWC 4ONTD 2ERJA 3ZD1A 4F4OC 4LOTA 1OK2A 3TVJA 1MD8A 1VVDA 3ERBA 2IZ3A 1G4GA 5HYTB 1SS2A 1O9AA 4AYIA 2RLPA 1QO6A 2W81A 2XRBA 2LOJA 1H03P 1ZJKA 4JHSA 2YRAA 1OK3A 1FBRA 3IU3I 1HFHA 1U5MA 1H2QP 3RJ3D 5HZPB 4K12A 1HFIA 4DJZA 3O8EB 1OJWA 4WJG2 1OJVA 3GXEA 3R62A 3KZJA 1GKNA 3SW0X 1VVCA 2EHFA 1GKGA 1TPMA 1Z92B 1TPNA 3GOVA 2G7IA 2RLQA 1QGBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1E5G A;  4AYD A;  4B2S A;  3OXU D;  2RKZ A;  4AYE A;  4A5W B;  4ZH1 D;  1OJY A;  2CG7 A;  2XWJ I;  2KRI A;  4J38 B;  2BZM A;  4FXG G;  2RKY A;  2JGX A;  3M7P A;  1MD7 A;  3INB C;  4KKD A;  2EC3 A;  2QY0 A;  1PPQ A;  5I0Q B;  5FO8 C;  5JPM G;  2MCZ A;  1HCC A;  3T5O A;  5HYU B;  1CKL A;  2MCY A;  3ZD2 A;  2B5I D;  2JRA A;  1GPZ A;  2YBY A;  3OED C;  1H04 P;  1SRZ A;  5HYP A;  3ZRZ A;  1OK1 A;  1TPG A;  4LOS A;  1E88 A;  1G4F A;  2IZ4 A;  2W80 A;  2UWN A;  1UOT P;  3OP8 A;  2XRD A;  4PZ5 A;  3MQL A;  4C16 A;  3KXV A;  3L89 M;  2KMS A;  4B2R A;  2A55 A;  1E8B A;  1LY2 A;  3CAL A;  4YNX A;  2CKU A;  1ELV A;  2V8E A;  2CG6 A;  2XWB F;  4MUC A;  1H2P P;  4CSY A;  2JGW A;  1C1Z A;  1QUB A;  1GHQ B;  4AYM A;  3EJH A;  3IX0 A;  4IGD A;  2WII C;  2O39 C;  2RL0 A;  1Q3X A;  1OK9 A;  1NWV A;  3NFP I;  2XQW C;  4ONT D;  2ERJ A;  3ZD1 A;  4F4O C;  4LOT A;  1OK2 A;  3TVJ A;  1MD8 A;  1VVD A;  3ERB A;  2IZ3 A;  1G4G A;  5HYT B;  1SS2 A;  1O9A A;  4AYI A;  2RLP A;  1QO6 A;  2W81 A;  2XRB A;  2LOJ A;  1H03 P;  1ZJK A;  4JHS A;  2YRA A;  1OK3 A;  1FBR A;  3IU3 I;  1HFH A;  1U5M A;  1H2Q P;  3RJ3 D;  5HZP B;  4K12 A;  1HFI A;  4DJZ A;  3O8E B;  1OJW A;  4WJG 2;  1OJV A;  3GXE A;  3R62 A;  3KZJ A;  1GKN A;  3SW0 X;  1VVC A;  2EHF A;  1GKG A;  1TPM A;  1Z92 B;  1TPN A;  3GOV A;  2G7I A;  2RLQ A;  1QGB A; 
#chains in the Genus database with same CATH topology
 1E5G A;  4AYD A;  4PO7 A;  4YIZ A;  4B2S A;  3OXU D;  2RKZ A;  4AYE A;  4A5W B;  4ZH1 D;  4N7E A;  1OJY A;  2CG7 A;  2XWJ I;  2KRI A;  4J38 B;  2I2L A;  2BZM A;  4FXG G;  2RKY A;  2JGX A;  3M7P A;  1MD7 A;  3INB C;  4KKD A;  2EC3 A;  3F6K A;  2QY0 A;  1PPQ A;  5I0Q B;  5FO8 C;  5JPM G;  2MCZ A;  1HCC A;  3T5O A;  5HYU B;  1CKL A;  2MCY A;  3ZD2 A;  2B5I D;  2JRA A;  1GPZ A;  4BWC A;  2YBY A;  3OED C;  1H04 P;  1SRZ A;  5HYP A;  3ZRZ A;  2X2Z A;  2Y8R A;  1OK1 A;  1TPG A;  4LOS A;  1E88 A;  3ZLE A;  1G4F A;  2IZ4 A;  2W80 A;  2UWN A;  1UOT P;  3OP8 A;  2XRD A;  3NJA A;  4PZ5 A;  3MQL A;  4C16 A;  3KXV A;  3L89 M;  3K3T A;  2KMS A;  4B2R A;  2A55 A;  1E8B A;  2ZYC A;  1RLH A;  3WSX A;  1LY2 A;  3CAL A;  4YNX A;  3ZLD A;  2CKU A;  1ELV A;  2V8E A;  2CG6 A;  4MSL A;  2XWB F;  4MUC A;  1H2P P;  4CSY A;  2JGW A;  3WSY A;  1C1Z A;  1QUB A;  1GHQ B;  2Y8T A;  4AYM A;  3EJH A;  3IX0 A;  2Y8S A;  4IGD A;  2WII C;  2O39 C;  2RL0 A;  1Q3X A;  1OK9 A;  1NWV A;  3NFP I;  2XQW C;  4ONT D;  2ERJ A;  3CI0 J;  3ZD1 A;  4F4O C;  4LOT A;  1OK2 A;  5DN4 A;  3TVJ A;  5DN5 A;  1MD8 A;  3FGR A;  1VVD A;  3ERB A;  2IZ3 A;  3FGT A;  1G4G A;  5HYT B;  1SS2 A;  1O9A A;  4AYI A;  4APL A;  2RLP A;  1QO6 A;  2W81 A;  2XRB A;  2LOJ A;  1H03 P;  1ZJK A;  4JHS A;  2YRA A;  1OK3 A;  1FBR A;  3VWO A;  3IU3 I;  1HFH A;  1U5M A;  1H2Q P;  3RJ3 D;  5HZP B;  4K12 A;  1HFI A;  4DJZ A;  3O8E B;  1OJW A;  4WJG 2;  1OJV A;  3GXE A;  3R62 A;  3KZJ A;  1GKN A;  3SW0 X;  1VVC A;  2EHF A;  1GKG A;  1TPM A;  1Z92 B;  1TPN A;  3GOV A;  2G7I A;  2RLQ A;  1QGB A; 
#chains in the Genus database with same CATH homology
 1E5G A;  4AYD A;  4B2S A;  3OXU D;  2RKZ A;  4AYE A;  4A5W B;  4ZH1 D;  1OJY A;  2CG7 A;  2XWJ I;  2KRI A;  4J38 B;  2BZM A;  4FXG G;  2RKY A;  2JGX A;  3M7P A;  1MD7 A;  3INB C;  4KKD A;  2EC3 A;  2QY0 A;  1PPQ A;  5I0Q B;  5FO8 C;  5JPM G;  2MCZ A;  1HCC A;  3T5O A;  5HYU B;  1CKL A;  2MCY A;  3ZD2 A;  2B5I D;  2JRA A;  1GPZ A;  2YBY A;  3OED C;  1H04 P;  1SRZ A;  5HYP A;  3ZRZ A;  1OK1 A;  1TPG A;  4LOS A;  1E88 A;  1G4F A;  2IZ4 A;  2W80 A;  2UWN A;  1UOT P;  3OP8 A;  2XRD A;  4PZ5 A;  3MQL A;  4C16 A;  3KXV A;  3L89 M;  2KMS A;  4B2R A;  2A55 A;  1E8B A;  1LY2 A;  3CAL A;  4YNX A;  2CKU A;  1ELV A;  2V8E A;  2CG6 A;  2XWB F;  4MUC A;  1H2P P;  4CSY A;  2JGW A;  1C1Z A;  1QUB A;  1GHQ B;  4AYM A;  3EJH A;  3IX0 A;  4IGD A;  2WII C;  2O39 C;  2RL0 A;  1Q3X A;  1OK9 A;  1NWV A;  3NFP I;  2XQW C;  4ONT D;  2ERJ A;  3ZD1 A;  4F4O C;  4LOT A;  1OK2 A;  3TVJ A;  1MD8 A;  1VVD A;  3ERB A;  2IZ3 A;  1G4G A;  5HYT B;  1SS2 A;  1O9A A;  4AYI A;  2RLP A;  1QO6 A;  2W81 A;  2XRB A;  2LOJ A;  1H03 P;  1ZJK A;  4JHS A;  2YRA A;  1OK3 A;  1FBR A;  3IU3 I;  1HFH A;  1U5M A;  1H2Q P;  3RJ3 D;  5HZP B;  4K12 A;  1HFI A;  4DJZ A;  3O8E B;  1OJW A;  4WJG 2;  1OJV A;  3GXE A;  3R62 A;  3KZJ A;  1GKN A;  3SW0 X;  1VVC A;  2EHF A;  1GKG A;  1TPM A;  1Z92 B;  1TPN A;  3GOV A;  2G7I A;  2RLQ A;  1QGB A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...