1OK9A

Decay accelerating factor (cd55): the structure of an intact human complement regulator.
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
254
structure length
254
Chain Sequence
MQDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Complement Regulation at the Molecular Level: The Structure of Decay-Accelerating Factor
pubmed doi rcsb
molecule keywords COMPLEMENT DECAY-ACCELERATING FACTOR
molecule tags Regulator of complement pathway
source organism Homo sapiens
total genus 36
structure length 254
sequence length 254
chains with identical sequence B
ec nomenclature
pdb deposition date 2003-07-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00084 Sushi Sushi repeat (SCR repeat)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1ok9A04
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1ok9A03
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1ok9A01
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1ok9A02
1QO6A 3KZJA 4AYIA 4FXGG 4B2SA 2W81A 1G4GA 2ERJA 4JHSA 2A55A 1HFIA 1MD7A 4CSYA 1VVCA 3M7PA 1H04P 3ERBA 1NWVA 3ZD1A 3TVJA 1GKGA 1ELVA 1MD8A 3GOVA 1PPQA 1FBRA 1ZJKA 5HYTB 1Z92B 3O8EB 1H2PP 2RKYA 1TPMA 2XRDA 2XQWC 1E8BA 1UOTP 2JRAA 4WJG2 3OP8A 2IZ3A 1VVDA 3R62A 1GPZA 2CG6A 2XWBF 2G7IA 1TPNA 1OJWA 3EJHA 2IZ4A 3INBC 2LOJA 2W80A 3SW0X 2YRAA 1SRZA 2RKZA 4B2RA 2QY0A 4YNXA 1H2QP 2KMSA 3ZRZA 2BZMA 2JGWA 1OK9A 1U5MA 1Q3XA 4F4OC 4AYMA 1E5GA 1E88A 5HYUB 5FO8C 4DJZA 4PZ5A 2XWJI 2B5ID 2XRBA 2UWNA 4ZH1D 5JPMG 1QUBA 3IU3I 3MQLA 1HCCA 1GKNA 4LOTA 4IGDA 2RL0A 3T5OA 3CALA 2JGXA 1LY2A 2RLPA 2V8EA 1OK2A 5HYPA 1OK3A 4AYEA 3IX0A 3OEDC 2YBYA 3RJ3D 1TPGA 2EC3A 1G4FA 4KKDA 1SS2A 2O39C 2CG7A 5I0QB 2MCZA 3ZD2A 1OJYA 2RLQA 4J38B 5HZPB 3L89M 1OJVA 4LOSA 4ONTD 4K12A 1H03P 1C1ZA 1CKLA 3GXEA 1QGBA 3NFPI 3OXUD 4MUCA 2EHFA 2KRIA 1HFHA 1O9AA 4A5WB 2WIIC 2MCYA 4AYDA 1GHQB 3KXVA 1OK1A 4C16A 2CKUA
chains in the Genus database with same CATH superfamily
1QO6A 3KZJA 2Y8SA 4AYIA 4FXGG 4YIZA 4B2SA 2W81A 1G4GA 2ERJA 3NJAA 2A55A 1HFIA 4JHSA 1RLHA 3F6KA 1MD7A 4CSYA 1VVCA 3M7PA 4MSLA 2I2LA 1H04P 3ERBA 4BWCA 5DN5A 1NWVA 3ZD1A 3TVJA 1GKGA 4N7EA 1ELVA 1MD8A 3GOVA 1PPQA 1FBRA 1ZJKA 5HYTB 1Z92B 3WSXA 3O8EB 1H2PP 2RKYA 1TPMA 2XRDA 2XQWC 1E8BA 1UOTP 2JRAA 4APLA 4WJG2 3OP8A 2IZ3A 1VVDA 3R62A 1GPZA 2CG6A 2XWBF 2G7IA 1TPNA 1OJWA 3EJHA 2IZ4A 3INBC 3FGTA 2LOJA 2W80A 3SW0X 2YRAA 1SRZA 2RKZA 4B2RA 2QY0A 4YNXA 1H2QP 2KMSA 3ZRZA 2BZMA 2JGWA 3ZLEA 1OK9A 1U5MA 2X2ZA 1Q3XA 4F4OC 4AYMA 1E5GA 1E88A 5HYUB 5FO8C 4DJZA 4PZ5A 4PO7A 2XWJI 2B5ID 2XRBA 2UWNA 4ZH1D 5JPMG 1QUBA 3IU3I 5DN4A 3MQLA 1HCCA 1GKNA 4LOTA 4IGDA 2RL0A 3T5OA 3CALA 2JGXA 1LY2A 2RLPA 2V8EA 1OK2A 5HYPA 1OK3A 3WSYA 3IX0A 4AYEA 3OEDC 2YBYA 2Y8RA 3RJ3D 1TPGA 2EC3A 1G4FA 3FGRA 4KKDA 1SS2A 2O39C 3VWOA 2CG7A 2ZYCA 5I0QB 2MCZA 2Y8TA 1OJYA 2RLQA 4J38B 3ZD2A 5HZPB 3L89M 1OJVA 3ZLDA 4LOSA 4ONTD 4K12A 1H03P 1C1ZA 1CKLA 3GXEA 1QGBA 3K3TA 3NFPI 3OXUD 4MUCA 2EHFA 2KRIA 1HFHA 1O9AA 4A5WB 2WIIC 2MCYA 4AYDA 1GHQB 3CI0J 3KXVA 1OK1A 4C16A 2CKUA
chains in the Genus database with same CATH topology
1QO6A 3KZJA 4AYIA 4FXGG 4B2SA 2W81A 1G4GA 2ERJA 4JHSA 2A55A 1HFIA 1MD7A 4CSYA 1VVCA 3M7PA 1H04P 3ERBA 1NWVA 3ZD1A 3TVJA 1GKGA 1ELVA 1MD8A 3GOVA 1PPQA 1FBRA 1ZJKA 5HYTB 1Z92B 3O8EB 1H2PP 2RKYA 1TPMA 2XRDA 2XQWC 1E8BA 1UOTP 2JRAA 4WJG2 3OP8A 2IZ3A 1VVDA 3R62A 1GPZA 2CG6A 2XWBF 2G7IA 1TPNA 1OJWA 3EJHA 2IZ4A 3INBC 2LOJA 2W80A 3SW0X 2YRAA 1SRZA 2RKZA 4B2RA 2QY0A 4YNXA 1H2QP 2KMSA 3ZRZA 2BZMA 2JGWA 1OK9A 1U5MA 1Q3XA 4F4OC 4AYMA 1E5GA 1E88A 5HYUB 5FO8C 4DJZA 4PZ5A 2XWJI 2B5ID 2XRBA 2UWNA 4ZH1D 5JPMG 1QUBA 3IU3I 3MQLA 1HCCA 1GKNA 4LOTA 4IGDA 2RL0A 3T5OA 3CALA 2JGXA 1LY2A 2RLPA 2V8EA 1OK2A 5HYPA 1OK3A 4AYEA 3IX0A 3OEDC 2YBYA 3RJ3D 1TPGA 2EC3A 1G4FA 4KKDA 1SS2A 2O39C 2CG7A 5I0QB 2MCZA 3ZD2A 1OJYA 2RLQA 4J38B 5HZPB 3L89M 1OJVA 4LOSA 4ONTD 4K12A 1H03P 1C1ZA 1CKLA 3GXEA 1QGBA 3NFPI 3OXUD 4MUCA 2EHFA 2KRIA 1HFHA 1O9AA 4A5WB 2WIIC 2MCYA 4AYDA 1GHQB 3KXVA 1OK1A 4C16A 2CKUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1QO6 A;  3KZJ A;  4AYI A;  4FXG G;  4B2S A;  2W81 A;  1G4G A;  2ERJ A;  4JHS A;  2A55 A;  1HFI A;  1MD7 A;  4CSY A;  1VVC A;  3M7P A;  1H04 P;  3ERB A;  1NWV A;  3ZD1 A;  3TVJ A;  1GKG A;  1ELV A;  1MD8 A;  3GOV A;  1PPQ A;  1FBR A;  1ZJK A;  5HYT B;  1Z92 B;  3O8E B;  1H2P P;  2RKY A;  1TPM A;  2XRD A;  2XQW C;  1E8B A;  1UOT P;  2JRA A;  4WJG 2;  3OP8 A;  2IZ3 A;  1VVD A;  3R62 A;  1GPZ A;  2CG6 A;  2XWB F;  2G7I A;  1TPN A;  1OJW A;  3EJH A;  2IZ4 A;  3INB C;  2LOJ A;  2W80 A;  3SW0 X;  2YRA A;  1SRZ A;  2RKZ A;  4B2R A;  2QY0 A;  4YNX A;  1H2Q P;  2KMS A;  3ZRZ A;  2BZM A;  2JGW A;  1OK9 A;  1U5M A;  1Q3X A;  4F4O C;  4AYM A;  1E5G A;  1E88 A;  5HYU B;  5FO8 C;  4DJZ A;  4PZ5 A;  2XWJ I;  2B5I D;  2XRB A;  2UWN A;  4ZH1 D;  5JPM G;  1QUB A;  3IU3 I;  3MQL A;  1HCC A;  1GKN A;  4LOT A;  4IGD A;  2RL0 A;  3T5O A;  3CAL A;  2JGX A;  1LY2 A;  2RLP A;  2V8E A;  1OK2 A;  5HYP A;  1OK3 A;  4AYE A;  3IX0 A;  3OED C;  2YBY A;  3RJ3 D;  1TPG A;  2EC3 A;  1G4F A;  4KKD A;  1SS2 A;  2O39 C;  2CG7 A;  5I0Q B;  2MCZ A;  3ZD2 A;  1OJY A;  2RLQ A;  4J38 B;  5HZP B;  3L89 M;  1OJV A;  4LOS A;  4ONT D;  4K12 A;  1H03 P;  1C1Z A;  1CKL A;  3GXE A;  1QGB A;  3NFP I;  3OXU D;  4MUC A;  2EHF A;  2KRI A;  1HFH A;  1O9A A;  4A5W B;  2WII C;  2MCY A;  4AYD A;  1GHQ B;  3KXV A;  1OK1 A;  4C16 A;  2CKU A; 
#chains in the Genus database with same CATH topology
 1QO6 A;  3KZJ A;  2Y8S A;  4AYI A;  4FXG G;  4YIZ A;  4B2S A;  2W81 A;  1G4G A;  2ERJ A;  3NJA A;  2A55 A;  1HFI A;  4JHS A;  1RLH A;  3F6K A;  1MD7 A;  4CSY A;  1VVC A;  3M7P A;  4MSL A;  2I2L A;  1H04 P;  3ERB A;  4BWC A;  5DN5 A;  1NWV A;  3ZD1 A;  3TVJ A;  1GKG A;  4N7E A;  1ELV A;  1MD8 A;  3GOV A;  1PPQ A;  1FBR A;  1ZJK A;  5HYT B;  1Z92 B;  3WSX A;  3O8E B;  1H2P P;  2RKY A;  1TPM A;  2XRD A;  2XQW C;  1E8B A;  1UOT P;  2JRA A;  4APL A;  4WJG 2;  3OP8 A;  2IZ3 A;  1VVD A;  3R62 A;  1GPZ A;  2CG6 A;  2XWB F;  2G7I A;  1TPN A;  1OJW A;  3EJH A;  2IZ4 A;  3INB C;  3FGT A;  2LOJ A;  2W80 A;  3SW0 X;  2YRA A;  1SRZ A;  2RKZ A;  4B2R A;  2QY0 A;  4YNX A;  1H2Q P;  2KMS A;  3ZRZ A;  2BZM A;  2JGW A;  3ZLE A;  1OK9 A;  1U5M A;  2X2Z A;  1Q3X A;  4F4O C;  4AYM A;  1E5G A;  1E88 A;  5HYU B;  5FO8 C;  4DJZ A;  4PZ5 A;  4PO7 A;  2XWJ I;  2B5I D;  2XRB A;  2UWN A;  4ZH1 D;  5JPM G;  1QUB A;  3IU3 I;  5DN4 A;  3MQL A;  1HCC A;  1GKN A;  4LOT A;  4IGD A;  2RL0 A;  3T5O A;  3CAL A;  2JGX A;  1LY2 A;  2RLP A;  2V8E A;  1OK2 A;  5HYP A;  1OK3 A;  3WSY A;  3IX0 A;  4AYE A;  3OED C;  2YBY A;  2Y8R A;  3RJ3 D;  1TPG A;  2EC3 A;  1G4F A;  3FGR A;  4KKD A;  1SS2 A;  2O39 C;  3VWO A;  2CG7 A;  2ZYC A;  5I0Q B;  2MCZ A;  2Y8T A;  1OJY A;  2RLQ A;  4J38 B;  3ZD2 A;  5HZP B;  3L89 M;  1OJV A;  3ZLD A;  4LOS A;  4ONT D;  4K12 A;  1H03 P;  1C1Z A;  1CKL A;  3GXE A;  1QGB A;  3K3T A;  3NFP I;  3OXU D;  4MUC A;  2EHF A;  2KRI A;  1HFH A;  1O9A A;  4A5W B;  2WII C;  2MCY A;  4AYD A;  1GHQ B;  3CI0 J;  3KXV A;  1OK1 A;  4C16 A;  2CKU A; 
#chains in the Genus database with same CATH homology
 1QO6 A;  3KZJ A;  4AYI A;  4FXG G;  4B2S A;  2W81 A;  1G4G A;  2ERJ A;  4JHS A;  2A55 A;  1HFI A;  1MD7 A;  4CSY A;  1VVC A;  3M7P A;  1H04 P;  3ERB A;  1NWV A;  3ZD1 A;  3TVJ A;  1GKG A;  1ELV A;  1MD8 A;  3GOV A;  1PPQ A;  1FBR A;  1ZJK A;  5HYT B;  1Z92 B;  3O8E B;  1H2P P;  2RKY A;  1TPM A;  2XRD A;  2XQW C;  1E8B A;  1UOT P;  2JRA A;  4WJG 2;  3OP8 A;  2IZ3 A;  1VVD A;  3R62 A;  1GPZ A;  2CG6 A;  2XWB F;  2G7I A;  1TPN A;  1OJW A;  3EJH A;  2IZ4 A;  3INB C;  2LOJ A;  2W80 A;  3SW0 X;  2YRA A;  1SRZ A;  2RKZ A;  4B2R A;  2QY0 A;  4YNX A;  1H2Q P;  2KMS A;  3ZRZ A;  2BZM A;  2JGW A;  1OK9 A;  1U5M A;  1Q3X A;  4F4O C;  4AYM A;  1E5G A;  1E88 A;  5HYU B;  5FO8 C;  4DJZ A;  4PZ5 A;  2XWJ I;  2B5I D;  2XRB A;  2UWN A;  4ZH1 D;  5JPM G;  1QUB A;  3IU3 I;  3MQL A;  1HCC A;  1GKN A;  4LOT A;  4IGD A;  2RL0 A;  3T5O A;  3CAL A;  2JGX A;  1LY2 A;  2RLP A;  2V8E A;  1OK2 A;  5HYP A;  1OK3 A;  4AYE A;  3IX0 A;  3OED C;  2YBY A;  3RJ3 D;  1TPG A;  2EC3 A;  1G4F A;  4KKD A;  1SS2 A;  2O39 C;  2CG7 A;  5I0Q B;  2MCZ A;  3ZD2 A;  1OJY A;  2RLQ A;  4J38 B;  5HZP B;  3L89 M;  1OJV A;  4LOS A;  4ONT D;  4K12 A;  1H03 P;  1C1Z A;  1CKL A;  3GXE A;  1QGB A;  3NFP I;  3OXU D;  4MUC A;  2EHF A;  2KRI A;  1HFH A;  1O9A A;  4A5W B;  2WII C;  2MCY A;  4AYD A;  1GHQ B;  3KXV A;  1OK1 A;  4C16 A;  2CKU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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