1OLPA

Alpha toxin from clostridium absonum
Total Genus 136
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
136
sequence length
370
structure length
370
Chain Sequence
WDGKEDGTGTHSVIVTQAIEMLKHDLSKDEPEAIRNDLSILEKNLHKFQLGSTFPDYDPNAYSLYQDHFWDPDTDHNFTQDNKWYLSYAVPDNAESQTRKFATLAKNEWDKGNYEKAAWYLGQGMHYFGDLNTPYHAANVTAVDSPGHVKFETYAEERKDTYRLDTTGYNTDDAFYKDTLKNDNFNEWSKGYCKYWAKKAKNLYYSHATMSNSWDDWEYAASHGVGNAQKGVAGYLYRFLNDVSNKDAVDKDYDLNEIVVMIKTADVQDAGTDNYIYFGIETKDGVKEEWALDNPGNDFTRNQEGTYTLKLKNKNTKYSDIKNMWIRDEKLTVATDGWKPSYVKVIAGDKVRLEKNINEWISGGTTYTLK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Clostridium Absonum Alpha-Toxin: New Insights Into Clostridial Phospholipase C Substrate Binding and Specificity
pubmed doi rcsb
molecule tags Hydrolase
source organism Clostridium sardiniense
molecule keywords ALPHA-TOXIN
total genus 136
structure length 370
sequence length 370
chains with identical sequence B, C, D
ec nomenclature ec 3.1.4.3: Phospholipase C.
pdb deposition date 2003-08-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00882 Zn_dep_PLPC Zinc dependent phospholipase C
A PF01477 PLAT PLAT/LH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.575.10 Mainly Alpha Orthogonal Bundle P1 Nuclease P1 Nuclease 1olpA01
2.60.60.20 Mainly Beta Sandwich Lipoxygenase-1 PLAT/LH2 domain 1olpA02
3V98A 2HUCA 1FGTA 1N8SA 4NREA 3O8YA 1KHOA 1Y4KA 1IK3A 4CXPA 3BNEA 3FG1A 1RP1A 1P5XA 2PPLA 5FBAA 1JNQA 3BNDA 2WXTA 5FB9A 3FG3A 3VF1A 1FGMA 5FBGA 3V92A 4CXVA 1W52X 5EEOA 5FBDA 1RRLA 1AK0A 1FGRA 4WFOA 4DJ4A 1LNHA 1RRHA 2PVSA 1P6EA 2FFZA 1CA1A 1OLPA 1F8NA 1QM6A 4CWMA 3BNCA 2WXUA 1FGOA 1AH7A 2SBLA 2IUKA 2FGNA 1NO3A 1QMDA 4WHAA 1HPLA 1LPAB 3BNBA 1ETHA 5FBCA 4QWTA 1BU8A 1N8QA 1ROVA 3CWZB 4JDGA 3PZWA 1HU9A 1GPLA 5FBFA 2IUJA 5FBBA 1LPBB 3SNGA 1P6DA 1YGEA 3FG4A 4CXOA 2OXEA 2FNQA 1LOXA 3V99A 1GYGA 2P0MA 1FGQA 2WY6A 3W52A
chains in the Genus database with same CATH superfamily
3V98A 2HUCA 1FGTA 1N8SA 4NREA 2QZ7A 3O8YA 1KHOA 1Y4KA 2XHJA 4CXPA 1IK3A 2XFDA 3BNEA 3FG1A 1RP1A 1P5XA 3IBZA 2PPLA 5FBAA 4QEYA 1JNQA 3BNDA 2LG7A 2WXTA 5FB9A 2LGEA 3FG3A 3VF1A 2KXVA 1FGMA 5FBGA 3V92A 4CXVA 1W52X 5EEOA 5FBDA 1RRLA 1AK0A 1FGRA 4WFOA 4DJ4A 1LNHA 1RRHA 2LRGA 2PVSA 1P6EA 2FFZA 1CA1A 1OLPA 1F8NA 1QM6A 4CWMA 3U6GA 2WXUA 3BNCA 2QNGA 1FGOA 1AH7A 2SBLA 2IUKA 2FGNA 1NO3A 1QMDA 4WHAA 1HPLA 1LPAB 2XHHA 3BNBA 1ETHA 5FBCA 4QWTA 1BU8A 1N8QA 1ROVA 3CWZB 4JDGA 3PZWA 1HU9A 1GPLA 5FBFA 2IUJA 5FBBA 1LPBB 3SNGA 2XFEA 1P6DA 1YGEA 3FG4A 4CXOA 2OXEA 2FNQA 1LOXA 3V99A 1GYGA 2P0MA 2KXTA 1FGQA 2WY6A 3W52A
chains in the Genus database with same CATH topology
3V98A 2HUCA 1FGTA 1N8SA 4NREA 3O8YA 1KHOA 1Y4KA 1IK3A 4CXPA 3BNEA 3FG1A 1RP1A 1P5XA 2PPLA 5FBAA 1JNQA 3BNDA 2WXTA 5FB9A 3FG3A 3VF1A 1FGMA 5FBGA 3V92A 4CXVA 1W52X 5EEOA 5FBDA 1RRLA 1AK0A 1FGRA 4WFOA 4DJ4A 1LNHA 1RRHA 2PVSA 1P6EA 2FFZA 1CA1A 1OLPA 1F8NA 1QM6A 4CWMA 3BNCA 2WXUA 1FGOA 1AH7A 2SBLA 2IUKA 2FGNA 1NO3A 1QMDA 4WHAA 1HPLA 1LPAB 3BNBA 1ETHA 5FBCA 4QWTA 1BU8A 1N8QA 1ROVA 3CWZB 4JDGA 3PZWA 1HU9A 1GPLA 5FBFA 2IUJA 5FBBA 1LPBB 3SNGA 1P6DA 1YGEA 3FG4A 4CXOA 2OXEA 2FNQA 1LOXA 3V99A 1GYGA 2P0MA 1FGQA 2WY6A 3W52A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3V98 A;  2HUC A;  1FGT A;  1N8S A;  4NRE A;  3O8Y A;  1KHO A;  1Y4K A;  1IK3 A;  4CXP A;  3BNE A;  3FG1 A;  1RP1 A;  1P5X A;  2PPL A;  5FBA A;  1JNQ A;  3BND A;  2WXT A;  5FB9 A;  3FG3 A;  3VF1 A;  1FGM A;  5FBG A;  3V92 A;  4CXV A;  1W52 X;  5EEO A;  5FBD A;  1RRL A;  1AK0 A;  1FGR A;  4WFO A;  4DJ4 A;  1LNH A;  1RRH A;  2PVS A;  1P6E A;  2FFZ A;  1CA1 A;  1OLP A;  1F8N A;  1QM6 A;  4CWM A;  3BNC A;  2WXU A;  1FGO A;  1AH7 A;  2SBL A;  2IUK A;  2FGN A;  1NO3 A;  1QMD A;  4WHA A;  1HPL A;  1LPA B;  3BNB A;  1ETH A;  5FBC A;  4QWT A;  1BU8 A;  1N8Q A;  1ROV A;  3CWZ B;  4JDG A;  3PZW A;  1HU9 A;  1GPL A;  5FBF A;  2IUJ A;  5FBB A;  1LPB B;  3SNG A;  1P6D A;  1YGE A;  3FG4 A;  4CXO A;  2OXE A;  2FNQ A;  1LOX A;  3V99 A;  1GYG A;  2P0M A;  1FGQ A;  2WY6 A;  3W52 A; 
#chains in the Genus database with same CATH topology
 3V98 A;  2HUC A;  1FGT A;  1N8S A;  4NRE A;  2QZ7 A;  3O8Y A;  1KHO A;  1Y4K A;  2XHJ A;  4CXP A;  1IK3 A;  2XFD A;  3BNE A;  3FG1 A;  1RP1 A;  1P5X A;  3IBZ A;  2PPL A;  5FBA A;  4QEY A;  1JNQ A;  3BND A;  2LG7 A;  2WXT A;  5FB9 A;  2LGE A;  3FG3 A;  3VF1 A;  2KXV A;  1FGM A;  5FBG A;  3V92 A;  4CXV A;  1W52 X;  5EEO A;  5FBD A;  1RRL A;  1AK0 A;  1FGR A;  4WFO A;  4DJ4 A;  1LNH A;  1RRH A;  2LRG A;  2PVS A;  1P6E A;  2FFZ A;  1CA1 A;  1OLP A;  1F8N A;  1QM6 A;  4CWM A;  3U6G A;  2WXU A;  3BNC A;  2QNG A;  1FGO A;  1AH7 A;  2SBL A;  2IUK A;  2FGN A;  1NO3 A;  1QMD A;  4WHA A;  1HPL A;  1LPA B;  2XHH A;  3BNB A;  1ETH A;  5FBC A;  4QWT A;  1BU8 A;  1N8Q A;  1ROV A;  3CWZ B;  4JDG A;  3PZW A;  1HU9 A;  1GPL A;  5FBF A;  2IUJ A;  5FBB A;  1LPB B;  3SNG A;  2XFE A;  1P6D A;  1YGE A;  3FG4 A;  4CXO A;  2OXE A;  2FNQ A;  1LOX A;  3V99 A;  1GYG A;  2P0M A;  2KXT A;  1FGQ A;  2WY6 A;  3W52 A; 
#chains in the Genus database with same CATH homology
 3V98 A;  2HUC A;  1FGT A;  1N8S A;  4NRE A;  3O8Y A;  1KHO A;  1Y4K A;  1IK3 A;  4CXP A;  3BNE A;  3FG1 A;  1RP1 A;  1P5X A;  2PPL A;  5FBA A;  1JNQ A;  3BND A;  2WXT A;  5FB9 A;  3FG3 A;  3VF1 A;  1FGM A;  5FBG A;  3V92 A;  4CXV A;  1W52 X;  5EEO A;  5FBD A;  1RRL A;  1AK0 A;  1FGR A;  4WFO A;  4DJ4 A;  1LNH A;  1RRH A;  2PVS A;  1P6E A;  2FFZ A;  1CA1 A;  1OLP A;  1F8N A;  1QM6 A;  4CWM A;  3BNC A;  2WXU A;  1FGO A;  1AH7 A;  2SBL A;  2IUK A;  2FGN A;  1NO3 A;  1QMD A;  4WHA A;  1HPL A;  1LPA B;  3BNB A;  1ETH A;  5FBC A;  4QWT A;  1BU8 A;  1N8Q A;  1ROV A;  3CWZ B;  4JDG A;  3PZW A;  1HU9 A;  1GPL A;  5FBF A;  2IUJ A;  5FBB A;  1LPB B;  3SNG A;  1P6D A;  1YGE A;  3FG4 A;  4CXO A;  2OXE A;  2FNQ A;  1LOX A;  3V99 A;  1GYG A;  2P0M A;  1FGQ A;  2WY6 A;  3W52 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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