1ONYA

Oxalyl-aryl-amino benzoic acid inhibitors of ptp1b, compound 17
Total Genus 99
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
99
sequence length
282
structure length
282
Chain Sequence
EMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery and Structure-Activity Relationship of Oxalylarylaminobenzoic Acids as Inhibitors of Protein Tyrosine Phosphatase 1B
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Protein-tyrosine phosphatase, non-receptor type 1
total genus 99
structure length 282
sequence length 282
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2003-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 1onyA00
4WTYA 2BIJA 4RI4A 3B7OA 2B4OA 3EB1A 2I6JA 1XRIA 4HJPA 2QCJA 1G1GA 3V0GA 2H02A 2VEVA 1YN9A 3MMJA 2M3VA 2HY3A 2F6VA 5KABA 4RI5A 4RKKA 3QCGA 1Q6TA 3ZM1A 3O4UA 2QBRA 2CJZA 1L8KA 2QEPA 3F99A 2NV5A 2OOQA 5KA0A 4R0TA 2CNGA 2YDUA 1QZ0A 1Q6JA 1NL9A 3RGQA 2JJDA 2F71A 2NTAA 2AHSA 2QBPA 1BZCA 2I4EA 1ZCLA 2GWOA 4GFVA 2P4DA 2HXPA 4QAHA 3AWFA 3A5JA 3QCJA 4BPCA 1YZ4A 5BZXA 3EU0A 1ECVA 5KA3A 3QCEA 2I6OA 2QCTA 5M43A 2Y96A 5IBSA 2DXPA 1PXHA 2HCMA 5BZZA 5KA1A 3QCFA 2OZ5A 3QCIA 1M3GA 3BRHA 3GXGA 1C85A 2I3UA 4WU3A 1JLNA 4S0GA 3F9AA 1YFOA 5EHPA 2BGDA 3S3FA 4QAPA 1XXVA 3A5KA 2MBCA 4I8NA 2FJMA 3QCNA 3S3KA 2B4PA 4GRZA 4IKCA 1ZCKA 2GP0A 4D3QA 1R6HA 5I6VA 3I80A 1PYNA 3O3LA 2F70A 1LQFA 1G4US 1Q6NA 3GXHA 3I36A 1FPZA 2F6YA 3OMHA 4GRYA 5KA9A 1AAXA 1KAVA 2CM2A 4ZN5A 1GWZA 2ESBA 1D5RA 2NT2A 4D3RA 3CM3A 5LXQB 1Q6MA 3S4OA 2QBSA 2HVLA 4NWGA 1WAXA 5KA8A 2F6TA 1V3AA 2BZLA 2Y2FA 2H4KA 1NO6A 3EZZA 3BLUA 4NWFA 4DGPA 2B4UA 4MBBA 2H04A 3M4UA 4GS0A 5IBMA 2I42A 1NNYA 2PA5A 4H1OA 3OLRA 3F81A 2PQ5A 1NWLA 2FH7A 3QCCA 3EAXA 1ONYA 1G1HA 3CWEA 3S3HA 3QKQA 4WU2A 4D3PA 2CM8A 2AZRA 3MOZA 4PVGA 3U96A 5K23A 1EENA 3D1OA 3RGOA 2QDMA 2B07A 1YTWA 1SUGA 1XXPA 3V0DA 4ERCA 2BGEA 1PTTA 1J4XA 3SMEA 2J17A 4GWFA 3V0HA 2I4GA 2HC1A 2ZMMA 4KI9A 1PA1A 4HJQA 3I7ZA 2PBNA 2CNFA 3MOWA 1YTSA 1U26A 4JMKA 4WOHA 1OEMX 1YWFA 2HNPA 4QBWA 4OHLA 4Y14A 4QUNA 2QDPA 4H34A 3V0EA 1GFYA 1EEOA 3D1QA 2I4HA 5KA4A 3D44A 2HNQA 2CMBA 2I3RA 3V0JA 3EMUA 2SHPA 1FQ1A 4B04A 2IMGA 3QCDA 4RH9A 2C7SA 2HB1A 3O4SA 1A5YA 1YPTA 2R0BA 2G6ZA 3QCKA 1YTNA 2WGPA 3O5XA 5AWXA 3D1HA 5HDEA 4NNDA 1BZHA 2CNHA 2CNIA 3ZM2A 2B4SA 2VEWA 4JNBA 4ICZA 5BX1A 2H03A 4TVVA 4GE2A 2VEYA 4J51A 3D9CA 3QCLA 2QBQA 1C87A 1PH0A 1YGRA 2H4VA 5MMZB 2VEXA 4ZI4A 4RHGA 2PT0A 2F46A 4GE5A 2I1YA 2GJTA 4AZ1A 1Q6PA 4GFUA 1G7GA 3QCHA 1I9SA 1X24A 2OC3A 3ZMQA 5KAAA 1OETA 3F41A 1PTUA 2I6MA 1L8GA 5GTJA 2Q05A 2NZ6A 1PA9A 5EHRA 1C83A 4GE6A 4QBEA 4KYRA 4ZRTA 1I9TA 2C46A 1P15A 3S4EA 2J16B 1OHDA 5KADA 4BJOA 3F9BA 3H2XA 1C86A 1RPMA 1T49A 2CFVA 1KAKA 1G4WR 1ZZWA 1U25A 2B3OA 1VHRA 1QXKA 3AWEA 3ZM0A 1YGUA 5K24A 4Z6BA 1Q6SA 3O4TA 4OHHA 2F6WA 5K22A 1ZC0A 2FJNA 1G1FA 1C88A 2I6IA 3QCMA 3NMEA 4NX8A 1NZ7A 4JBCA 2ZN7A 4R0SA 1LYVA 3BLTA 5J8RA 2PI7A 2RF6A 4NYHA 4OHDA 2BV5A 1WCHA 2NT7A 5K25A 1WRMA 3RO1A 5BUGA 1OHEA 1RXDA 1Q1MA 4HRFA 2I5XA 4QUMA 3S3EA 1ONZA 1PTVA 3LJ8A 4KYQA 4R30A 4DGXA 2A8BA 3V0IA 3RZ2A 2QDCA 3ZMPA 2I75A 2CM3A 2PSZA 2P6XA 1OEUA 2CMCA 1G7FA 2F6FA 2HC2A 2H4GA 3D42A 2CM7A 4JMJA 4YAAA 1OHCA 1XBOA 1C84A 3QKPA 4RH5A 2Q47A 3QCBA 3BM8A 2I6PA 2CMAA 2A3KA 4Y2EA 5K9WA 1T48A 2J16A 2F6ZA 1MKPA 4RDDA 1OEVA 1XM2A 2CNEA 3ZM3A 4YR8B 2E0TA 5KA7A 1U24A 2OUDA 3PS5A 5KACA 3ZV2A 1OESA 3V0FA 2G59A 1LARA 4PYHA 1T4JA 2NLKA 4OHIA 5KA2A 4OHEA 1NWEA 1FPRA 2B49A 3AWGA 1PTYA 1OEOX 5K9VA 1JF7A 2VEUA 3N0AA 1BZJA 3SR9A 1I57A
chains in the Genus database with same CATH superfamily
4WTYA 2BIJA 4RI4A 3B7OA 2B4OA 3EB1A 2I6JA 1EEHA 1XRIA 4HJPA 2GC5A 2QCJA 1G1GA 2UAGA 3V0GA 2H02A 2VEVA 1YN9A 3MMJA 2M3VA 2HY3A 2F6VA 5KABA 4RI5A 4RKKA 3QCGA 1Q6TA 3ZM1A 3O4UA 2QBRA 2CJZA 1L8KA 2QEPA 3F99A 4C12A 1E0DA 2NV5A 2OOQA 5KA0A 4R0TA 2CNGA 2YDUA 1QZ0A 1Q6JA 1NL9A 3RGQA 2JJDA 2F71A 2NTAA 2AHSA 2QBPA 1BZCA 2I4EA 3ZM5A 1ZCLA 2GWOA 4GFVA 2P4DA 2HXPA 4QAHA 3AWFA 3A5JA 3QCJA 4BPCA 1YZ4A 5BZXA 3EU0A 1ECVA 5KA3A 3QCEA 2I6OA 2QCTA 5M43A 1J6UA 2Y96A 1E8CA 5IBSA 2DXPA 1PXHA 2HCMA 5BZZA 5KA1A 3QCFA 2OZ5A 3QCIA 2JFHA 1M3GA 3NRSA 3BRHA 3GXGA 1C85A 2I3UA 2UUOA 4WU3A 1JLNA 4S0GA 1O5ZA 3F9AA 2XPCA 1YFOA 5EHPA 2BGDA 3S3FA 2AM1A 4QAPA 1XXVA 3A5KA 2MBCA 4I8NA 2FJMA 3QCNA 3S3KA 2B4PA 4GRZA 4IKCA 1ZCKA 2GP0A 4D3QA 1R6HA 5I6VA 3I80A 1PYNA 3O3LA 2F70A 1LQFA 1G4US 1Q6NA 3GXHA 3I36A 1FPZA 2F6YA 3OMHA 4GRYA 5KA9A 1AAXA 1KAVA 4BUCA 2CM2A 4ZN5A 1GWZA 2ESBA 1D5RA 2NT2A 4HV4A 4D3RA 3CM3A 5LXQB 1Q6MA 3S4OA 2QBSA 2HVLA 1P31A 4NWGA 1WAXA 5KA8A 2F6TA 1V3AA 2BZLA 2Y2FA 2H4KA 1NO6A 3EZZA 3BLUA 4NWFA 4DGPA 2B4UA 4MBBA 2H04A 1P3DA 3M4UA 4GS0A 5IBMA 2I42A 1NNYA 2PA5A 3ZL8A 4H1OA 3OLRA 3F81A 2PQ5A 1NWLA 2WJPA 2FH7A 3QCCA 3EAXA 1ONYA 4QF5A 1G1HA 3CWEA 3S3HA 3QKQA 4WU2A 4D3PA 2CM8A 2GCAA 2AZRA 3MOZA 4PVGA 3N2AA 3QCZA 3U96A 5K23A 1FGSA 2JFFA 1EENA 3D1OA 4UAGA 3RGOA 2Y1OA 2QDMA 2B07A 1YTWA 1SUGA 1XXPA 3V0DA 4CVMA 4ERCA 2BGEA 1PTTA 1J4XA 5A5EA 4CVKA 3SMEA 2VTDA 2J17A 4GWFA 2WTZA 3V0HA 2I4GA 2HC1A 2ZMMA 4KI9A 1PA1A 2Y66A 1GQYA 4C13A 4HJQA 3I7ZA 2PBNA 2CNFA 3MOWA 1YTSA 1U26A 4JMKA 4WOHA 1OEMX 1YWFA 2HNPA 4QBWA 2Y68A 4OHLA 4Y14A 4QUNA 2QDPA 4H34A 3V0EA 1GFYA 1EEOA 3D1QA 2I4HA 5KA4A 3D44A 2HNQA 2CMBA 2I3RA 3V0JA 3EMUA 2SHPA 1FQ1A 4B04A 2IMGA 1GQQA 3QCDA 4RH9A 2C7SA 2HB1A 3O4SA 5A5FA 1A5YA 1YPTA 2R0BA 2G6ZA 3QCKA 3ZM6A 1YTNA 3UAGA 2WGPA 3O5XA 5AWXA 3D1HA 5HDEA 4NNDA 1BZHA 2CNHA 2VORA 2CNIA 3ZM2A 2B4SA 2VEWA 4JNBA 4ICZA 5BX1A 2H03A 4TVVA 4GE2A 2VEYA 4J51A 3D9CA 3QCLA 2QBQA 1C87A 1PH0A 1YGRA 2H4VA 5MMZB 2VEXA 4ZI4A 4RHGA 2PT0A 2F46A 4GE5A 2I1YA 2GJTA 4AZ1A 1Q6PA 3PYZA 4GFUA 1W7KA 3MVNA 1G7GA 2GCBA 4QDIA 3QCHA 1I9SA 1X24A 2OC3A 3ZMQA 5KAAA 1OETA 3F41A 1PTUA 2I6MA 1L8GA 5GTJA 2Q05A 2NZ6A 1PA9A 2Y67A 1W78A 5EHRA 2VTEA 1C83A 4GE6A 4QBEA 4KYRA 2JFGA 4ZRTA 1I9TA 2C46A 1P15A 3S4EA 2J16B 1OHDA 5KADA 4BJOA 3F9BA 3H2XA 1C86A 1RPMA 2XJAA 1T49A 1KAKA 1G4WR 2CFVA 1ZZWA 1U25A 4BUBA 2B3OA 1VHRA 1QXKA 3AWEA 3ZM0A 2X5OA 1YGUA 5K24A 4Z6BA 1Q6SA 3O4TA 4OHHA 2F6WA 4CVLA 5K22A 1ZC0A 2FJNA 1G1FA 1C88A 2I6IA 3QCMA 3NMEA 4NX8A 1NZ7A 4JBCA 2ZN7A 2F00A 4R0SA 1LYVA 3BLTA 5J8RA 2PI7A 2RF6A 4NYHA 4OHDA 2BV5A 1WCHA 2NT7A 5K25A 1GG4A 1WRMA 3RO1A 5BUGA 1OHEA 1RXDA 2VOSA 1Q1MA 4HRFA 2I5XA 4QUMA 3S3EA 3HN7A 2GC6A 1ONZA 1PTVA 3LJ8A 4KYQA 4R30A 4DGXA 1JBWA 2A8BA 3V0IA 1JBVA 3RZ2A 2QDCA 3ZMPA 2I75A 2CM3A 2PSZA 2P6XA 1OEUA 3LK7A 2CMCA 1G7FA 2F6FA 2HC2A 2H4GA 3D42A 2CM7A 4JMJA 4YAAA 1OHCA 1XBOA 1C84A 1UAGA 3QKPA 4RH5A 2Q47A 3QCBA 3BM8A 2I6PA 2CMAA 2A3KA 4Y2EA 5K9WA 1T48A 2J16A 2F6ZA 1MKPA 4RDDA 1OEVA 1XM2A 2CNEA 3ZM3A 4YR8B 2E0TA 5KA7A 1U24A 2OUDA 3PS5A 5KACA 2UUPA 4ZIYA 3ZV2A 1OESA 3V0FA 2G59A 1LARA 4PYHA 1T4JA 2NLKA 4OHIA 5KA2A 4OHEA 1NWEA 1FPRA 2B49A 3AWGA 1PTYA 1OEOX 5K9VA 1JF7A 2VEUA 3N0AA 2AM2A 1BZJA 3SR9A 1I57A
chains in the Genus database with same CATH topology
4WTYA 2BIJA 4RI4A 3B7OA 2B4OA 3EB1A 2I6JA 1XRIA 4HJPA 2QCJA 1G1GA 3V0GA 2H02A 2VEVA 1YN9A 3MMJA 2M3VA 2HY3A 2F6VA 5KABA 4RI5A 4RKKA 3QCGA 1Q6TA 3ZM1A 3O4UA 2QBRA 2CJZA 1L8KA 2QEPA 3F99A 2NV5A 2OOQA 5KA0A 4R0TA 2CNGA 2YDUA 1QZ0A 1Q6JA 1NL9A 3RGQA 2JJDA 2F71A 2NTAA 2AHSA 2QBPA 1BZCA 2I4EA 1ZCLA 2GWOA 4GFVA 2P4DA 2HXPA 4QAHA 3AWFA 3A5JA 3QCJA 4BPCA 1YZ4A 5BZXA 3EU0A 1ECVA 5KA3A 3QCEA 2I6OA 2QCTA 5M43A 2Y96A 5IBSA 2DXPA 1PXHA 2HCMA 5BZZA 5KA1A 3QCFA 2OZ5A 3QCIA 1M3GA 3BRHA 3GXGA 1C85A 2I3UA 4WU3A 1JLNA 4S0GA 3F9AA 1YFOA 5EHPA 2BGDA 3S3FA 4QAPA 1XXVA 3A5KA 2MBCA 4I8NA 2FJMA 3QCNA 3S3KA 2B4PA 4GRZA 4IKCA 1ZCKA 2GP0A 4D3QA 1R6HA 5I6VA 3I80A 1PYNA 3O3LA 2F70A 1LQFA 1G4US 1Q6NA 3GXHA 3I36A 1FPZA 2F6YA 3OMHA 4GRYA 5KA9A 1AAXA 1KAVA 2CM2A 4ZN5A 1GWZA 2ESBA 1D5RA 2NT2A 4D3RA 3CM3A 5LXQB 1Q6MA 3S4OA 2QBSA 2HVLA 4NWGA 1WAXA 5KA8A 2F6TA 1V3AA 2BZLA 2Y2FA 2H4KA 1NO6A 3EZZA 3BLUA 4NWFA 4DGPA 2B4UA 4MBBA 2H04A 3M4UA 4GS0A 5IBMA 2I42A 1NNYA 2PA5A 4H1OA 3OLRA 3F81A 2PQ5A 1NWLA 2FH7A 3QCCA 3EAXA 1ONYA 1G1HA 3CWEA 3S3HA 3QKQA 4WU2A 4D3PA 2CM8A 2AZRA 3MOZA 4PVGA 3U96A 5K23A 1EENA 3D1OA 3RGOA 2QDMA 2B07A 1YTWA 1SUGA 1XXPA 3V0DA 4ERCA 2BGEA 1PTTA 1J4XA 3SMEA 2J17A 4GWFA 3V0HA 2I4GA 2HC1A 2ZMMA 4KI9A 1PA1A 4HJQA 3I7ZA 2PBNA 2CNFA 3MOWA 1YTSA 1U26A 4JMKA 4WOHA 1OEMX 1YWFA 2HNPA 4QBWA 4OHLA 4Y14A 4QUNA 2QDPA 4H34A 3V0EA 1GFYA 1EEOA 3D1QA 2I4HA 5KA4A 3D44A 2HNQA 2CMBA 2I3RA 3V0JA 3EMUA 2SHPA 1FQ1A 4B04A 2IMGA 3QCDA 4RH9A 2C7SA 2HB1A 3O4SA 1A5YA 1YPTA 2R0BA 2G6ZA 3QCKA 1YTNA 2WGPA 3O5XA 5AWXA 3D1HA 5HDEA 4NNDA 1BZHA 2CNHA 2CNIA 3ZM2A 2B4SA 2VEWA 4JNBA 4ICZA 5BX1A 2H03A 4TVVA 4GE2A 2VEYA 4J51A 3D9CA 3QCLA 2QBQA 1C87A 1PH0A 1YGRA 2H4VA 5MMZB 2VEXA 4ZI4A 4RHGA 2PT0A 2F46A 4GE5A 2I1YA 2GJTA 4AZ1A 1Q6PA 4GFUA 1G7GA 3QCHA 1I9SA 1X24A 2OC3A 3ZMQA 5KAAA 1OETA 3F41A 1PTUA 2I6MA 1L8GA 5GTJA 2Q05A 2NZ6A 1PA9A 5EHRA 1C83A 4GE6A 4QBEA 4KYRA 4ZRTA 1I9TA 2C46A 1P15A 3S4EA 2J16B 1OHDA 5KADA 4BJOA 3F9BA 3H2XA 1C86A 1RPMA 1T49A 2CFVA 1KAKA 1G4WR 1ZZWA 1U25A 2B3OA 1VHRA 1QXKA 3AWEA 3ZM0A 1YGUA 5K24A 4Z6BA 1Q6SA 3O4TA 4OHHA 2F6WA 5K22A 1ZC0A 2FJNA 1G1FA 1C88A 2I6IA 3QCMA 3NMEA 4NX8A 1NZ7A 4JBCA 2ZN7A 4R0SA 1LYVA 3BLTA 5J8RA 2PI7A 2RF6A 4NYHA 4OHDA 2BV5A 1WCHA 2NT7A 5K25A 1WRMA 3RO1A 5BUGA 1OHEA 1RXDA 1Q1MA 4HRFA 2I5XA 4QUMA 3S3EA 1ONZA 1PTVA 3LJ8A 4KYQA 4R30A 4DGXA 2A8BA 3V0IA 3RZ2A 2QDCA 3ZMPA 2I75A 2CM3A 2PSZA 2P6XA 1OEUA 2CMCA 1G7FA 2F6FA 2HC2A 2H4GA 3D42A 2CM7A 4JMJA 4YAAA 1OHCA 1XBOA 1C84A 3QKPA 4RH5A 2Q47A 3QCBA 3BM8A 2I6PA 2CMAA 2A3KA 4Y2EA 5K9WA 1T48A 2J16A 2F6ZA 1MKPA 4RDDA 1OEVA 1XM2A 2CNEA 3ZM3A 4YR8B 2E0TA 5KA7A 1U24A 2OUDA 3PS5A 5KACA 3ZV2A 1OESA 3V0FA 2G59A 1LARA 4PYHA 1T4JA 2NLKA 4OHIA 5KA2A 4OHEA 1NWEA 1FPRA 2B49A 3AWGA 1PTYA 1OEOX 5K9VA 1JF7A 2VEUA 3N0AA 1BZJA 3SR9A 1I57A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WTY A;  2BIJ A;  4RI4 A;  3B7O A;  2B4O A;  3EB1 A;  2I6J A;  1XRI A;  4HJP A;  2QCJ A;  1G1G A;  3V0G A;  2H02 A;  2VEV A;  1YN9 A;  3MMJ A;  2M3V A;  2HY3 A;  2F6V A;  5KAB A;  4RI5 A;  4RKK A;  3QCG A;  1Q6T A;  3ZM1 A;  3O4U A;  2QBR A;  2CJZ A;  1L8K A;  2QEP A;  3F99 A;  2NV5 A;  2OOQ A;  5KA0 A;  4R0T A;  2CNG A;  2YDU A;  1QZ0 A;  1Q6J A;  1NL9 A;  3RGQ A;  2JJD A;  2F71 A;  2NTA A;  2AHS A;  2QBP A;  1BZC A;  2I4E A;  1ZCL A;  2GWO A;  4GFV A;  2P4D A;  2HXP A;  4QAH A;  3AWF A;  3A5J A;  3QCJ A;  4BPC A;  1YZ4 A;  5BZX A;  3EU0 A;  1ECV A;  5KA3 A;  3QCE A;  2I6O A;  2QCT A;  5M43 A;  2Y96 A;  5IBS A;  2DXP A;  1PXH A;  2HCM A;  5BZZ A;  5KA1 A;  3QCF A;  2OZ5 A;  3QCI A;  1M3G A;  3BRH A;  3GXG A;  1C85 A;  2I3U A;  4WU3 A;  1JLN A;  4S0G A;  3F9A A;  1YFO A;  5EHP A;  2BGD A;  3S3F A;  4QAP A;  1XXV A;  3A5K A;  2MBC A;  4I8N A;  2FJM A;  3QCN A;  3S3K A;  2B4P A;  4GRZ A;  4IKC A;  1ZCK A;  2GP0 A;  4D3Q A;  1R6H A;  5I6V A;  3I80 A;  1PYN A;  3O3L A;  2F70 A;  1LQF A;  1G4U S;  1Q6N A;  3GXH A;  3I36 A;  1FPZ A;  2F6Y A;  3OMH A;  4GRY A;  5KA9 A;  1AAX A;  1KAV A;  2CM2 A;  4ZN5 A;  1GWZ A;  2ESB A;  1D5R A;  2NT2 A;  4D3R A;  3CM3 A;  5LXQ B;  1Q6M A;  3S4O A;  2QBS A;  2HVL A;  4NWG A;  1WAX A;  5KA8 A;  2F6T A;  1V3A A;  2BZL A;  2Y2F A;  2H4K A;  1NO6 A;  3EZZ A;  3BLU A;  4NWF A;  4DGP A;  2B4U A;  4MBB A;  2H04 A;  3M4U A;  4GS0 A;  5IBM A;  2I42 A;  1NNY A;  2PA5 A;  4H1O A;  3OLR A;  3F81 A;  2PQ5 A;  1NWL A;  2FH7 A;  3QCC A;  3EAX A;  1ONY A;  1G1H A;  3CWE A;  3S3H A;  3QKQ A;  4WU2 A;  4D3P A;  2CM8 A;  2AZR A;  3MOZ A;  4PVG A;  3U96 A;  5K23 A;  1EEN A;  3D1O A;  3RGO A;  2QDM A;  2B07 A;  1YTW A;  1SUG A;  1XXP A;  3V0D A;  4ERC A;  2BGE A;  1PTT A;  1J4X A;  3SME A;  2J17 A;  4GWF A;  3V0H A;  2I4G A;  2HC1 A;  2ZMM A;  4KI9 A;  1PA1 A;  4HJQ A;  3I7Z A;  2PBN A;  2CNF A;  3MOW A;  1YTS A;  1U26 A;  4JMK A;  4WOH A;  1OEM X;  1YWF A;  2HNP A;  4QBW A;  4OHL A;  4Y14 A;  4QUN A;  2QDP A;  4H34 A;  3V0E A;  1GFY A;  1EEO A;  3D1Q A;  2I4H A;  5KA4 A;  3D44 A;  2HNQ A;  2CMB A;  2I3R A;  3V0J A;  3EMU A;  2SHP A;  1FQ1 A;  4B04 A;  2IMG A;  3QCD A;  4RH9 A;  2C7S A;  2HB1 A;  3O4S A;  1A5Y A;  1YPT A;  2R0B A;  2G6Z A;  3QCK A;  1YTN A;  2WGP A;  3O5X A;  5AWX A;  3D1H A;  5HDE A;  4NND A;  1BZH A;  2CNH A;  2CNI A;  3ZM2 A;  2B4S A;  2VEW A;  4JNB A;  4ICZ A;  5BX1 A;  2H03 A;  4TVV A;  4GE2 A;  2VEY A;  4J51 A;  3D9C A;  3QCL A;  2QBQ A;  1C87 A;  1PH0 A;  1YGR A;  2H4V A;  5MMZ B;  2VEX A;  4ZI4 A;  4RHG A;  2PT0 A;  2F46 A;  4GE5 A;  2I1Y A;  2GJT A;  4AZ1 A;  1Q6P A;  4GFU A;  1G7G A;  3QCH A;  1I9S A;  1X24 A;  2OC3 A;  3ZMQ A;  5KAA A;  1OET A;  3F41 A;  1PTU A;  2I6M A;  1L8G A;  5GTJ A;  2Q05 A;  2NZ6 A;  1PA9 A;  5EHR A;  1C83 A;  4GE6 A;  4QBE A;  4KYR A;  4ZRT A;  1I9T A;  2C46 A;  1P15 A;  3S4E A;  2J16 B;  1OHD A;  5KAD A;  4BJO A;  3F9B A;  3H2X A;  1C86 A;  1RPM A;  1T49 A;  2CFV A;  1KAK A;  1G4W R;  1ZZW A;  1U25 A;  2B3O A;  1VHR A;  1QXK A;  3AWE A;  3ZM0 A;  1YGU A;  5K24 A;  4Z6B A;  1Q6S A;  3O4T A;  4OHH A;  2F6W A;  5K22 A;  1ZC0 A;  2FJN A;  1G1F A;  1C88 A;  2I6I A;  3QCM A;  3NME A;  4NX8 A;  1NZ7 A;  4JBC A;  2ZN7 A;  4R0S A;  1LYV A;  3BLT A;  5J8R A;  2PI7 A;  2RF6 A;  4NYH A;  4OHD A;  2BV5 A;  1WCH A;  2NT7 A;  5K25 A;  1WRM A;  3RO1 A;  5BUG A;  1OHE A;  1RXD A;  1Q1M A;  4HRF A;  2I5X A;  4QUM A;  3S3E A;  1ONZ A;  1PTV A;  3LJ8 A;  4KYQ A;  4R30 A;  4DGX A;  2A8B A;  3V0I A;  3RZ2 A;  2QDC A;  3ZMP A;  2I75 A;  2CM3 A;  2PSZ A;  2P6X A;  1OEU A;  2CMC A;  1G7F A;  2F6F A;  2HC2 A;  2H4G A;  3D42 A;  2CM7 A;  4JMJ A;  4YAA A;  1OHC A;  1XBO A;  1C84 A;  3QKP A;  4RH5 A;  2Q47 A;  3QCB A;  3BM8 A;  2I6P A;  2CMA A;  2A3K A;  4Y2E A;  5K9W A;  1T48 A;  2J16 A;  2F6Z A;  1MKP A;  4RDD A;  1OEV A;  1XM2 A;  2CNE A;  3ZM3 A;  4YR8 B;  2E0T A;  5KA7 A;  1U24 A;  2OUD A;  3PS5 A;  5KAC A;  3ZV2 A;  1OES A;  3V0F A;  2G59 A;  1LAR A;  4PYH A;  1T4J A;  2NLK A;  4OHI A;  5KA2 A;  4OHE A;  1NWE A;  1FPR A;  2B49 A;  3AWG A;  1PTY A;  1OEO X;  5K9V A;  1JF7 A;  2VEU A;  3N0A A;  1BZJ A;  3SR9 A;  1I57 A; 
#chains in the Genus database with same CATH topology
 4WTY A;  2BIJ A;  4RI4 A;  3B7O A;  2B4O A;  3EB1 A;  2I6J A;  1EEH A;  1XRI A;  4HJP A;  2GC5 A;  2QCJ A;  1G1G A;  2UAG A;  3V0G A;  2H02 A;  2VEV A;  1YN9 A;  3MMJ A;  2M3V A;  2HY3 A;  2F6V A;  5KAB A;  4RI5 A;  4RKK A;  3QCG A;  1Q6T A;  3ZM1 A;  3O4U A;  2QBR A;  2CJZ A;  1L8K A;  2QEP A;  3F99 A;  4C12 A;  1E0D A;  2NV5 A;  2OOQ A;  5KA0 A;  4R0T A;  2CNG A;  2YDU A;  1QZ0 A;  1Q6J A;  1NL9 A;  3RGQ A;  2JJD A;  2F71 A;  2NTA A;  2AHS A;  2QBP A;  1BZC A;  2I4E A;  3ZM5 A;  1ZCL A;  2GWO A;  4GFV A;  2P4D A;  2HXP A;  4QAH A;  3AWF A;  3A5J A;  3QCJ A;  4BPC A;  1YZ4 A;  5BZX A;  3EU0 A;  1ECV A;  5KA3 A;  3QCE A;  2I6O A;  2QCT A;  5M43 A;  1J6U A;  2Y96 A;  1E8C A;  5IBS A;  2DXP A;  1PXH A;  2HCM A;  5BZZ A;  5KA1 A;  3QCF A;  2OZ5 A;  3QCI A;  2JFH A;  1M3G A;  3NRS A;  3BRH A;  3GXG A;  1C85 A;  2I3U A;  2UUO A;  4WU3 A;  1JLN A;  4S0G A;  1O5Z A;  3F9A A;  2XPC A;  1YFO A;  5EHP A;  2BGD A;  3S3F A;  2AM1 A;  4QAP A;  1XXV A;  3A5K A;  2MBC A;  4I8N A;  2FJM A;  3QCN A;  3S3K A;  2B4P A;  4GRZ A;  4IKC A;  1ZCK A;  2GP0 A;  4D3Q A;  1R6H A;  5I6V A;  3I80 A;  1PYN A;  3O3L A;  2F70 A;  1LQF A;  1G4U S;  1Q6N A;  3GXH A;  3I36 A;  1FPZ A;  2F6Y A;  3OMH A;  4GRY A;  5KA9 A;  1AAX A;  1KAV A;  4BUC A;  2CM2 A;  4ZN5 A;  1GWZ A;  2ESB A;  1D5R A;  2NT2 A;  4HV4 A;  4D3R A;  3CM3 A;  5LXQ B;  1Q6M A;  3S4O A;  2QBS A;  2HVL A;  1P31 A;  4NWG A;  1WAX A;  5KA8 A;  2F6T A;  1V3A A;  2BZL A;  2Y2F A;  2H4K A;  1NO6 A;  3EZZ A;  3BLU A;  4NWF A;  4DGP A;  2B4U A;  4MBB A;  2H04 A;  1P3D A;  3M4U A;  4GS0 A;  5IBM A;  2I42 A;  1NNY A;  2PA5 A;  3ZL8 A;  4H1O A;  3OLR A;  3F81 A;  2PQ5 A;  1NWL A;  2WJP A;  2FH7 A;  3QCC A;  3EAX A;  1ONY A;  4QF5 A;  1G1H A;  3CWE A;  3S3H A;  3QKQ A;  4WU2 A;  4D3P A;  2CM8 A;  2GCA A;  2AZR A;  3MOZ A;  4PVG A;  3N2A A;  3QCZ A;  3U96 A;  5K23 A;  1FGS A;  2JFF A;  1EEN A;  3D1O A;  4UAG A;  3RGO A;  2Y1O A;  2QDM A;  2B07 A;  1YTW A;  1SUG A;  1XXP A;  3V0D A;  4CVM A;  4ERC A;  2BGE A;  1PTT A;  1J4X A;  5A5E A;  4CVK A;  3SME A;  2VTD A;  2J17 A;  4GWF A;  2WTZ A;  3V0H A;  2I4G A;  2HC1 A;  2ZMM A;  4KI9 A;  1PA1 A;  2Y66 A;  1GQY A;  4C13 A;  4HJQ A;  3I7Z A;  2PBN A;  2CNF A;  3MOW A;  1YTS A;  1U26 A;  4JMK A;  4WOH A;  1OEM X;  1YWF A;  2HNP A;  4QBW A;  2Y68 A;  4OHL A;  4Y14 A;  4QUN A;  2QDP A;  4H34 A;  3V0E A;  1GFY A;  1EEO A;  3D1Q A;  2I4H A;  5KA4 A;  3D44 A;  2HNQ A;  2CMB A;  2I3R A;  3V0J A;  3EMU A;  2SHP A;  1FQ1 A;  4B04 A;  2IMG A;  1GQQ A;  3QCD A;  4RH9 A;  2C7S A;  2HB1 A;  3O4S A;  5A5F A;  1A5Y A;  1YPT A;  2R0B A;  2G6Z A;  3QCK A;  3ZM6 A;  1YTN A;  3UAG A;  2WGP A;  3O5X A;  5AWX A;  3D1H A;  5HDE A;  4NND A;  1BZH A;  2CNH A;  2VOR A;  2CNI A;  3ZM2 A;  2B4S A;  2VEW A;  4JNB A;  4ICZ A;  5BX1 A;  2H03 A;  4TVV A;  4GE2 A;  2VEY A;  4J51 A;  3D9C A;  3QCL A;  2QBQ A;  1C87 A;  1PH0 A;  1YGR A;  2H4V A;  5MMZ B;  2VEX A;  4ZI4 A;  4RHG A;  2PT0 A;  2F46 A;  4GE5 A;  2I1Y A;  2GJT A;  4AZ1 A;  1Q6P A;  3PYZ A;  4GFU A;  1W7K A;  3MVN A;  1G7G A;  2GCB A;  4QDI A;  3QCH A;  1I9S A;  1X24 A;  2OC3 A;  3ZMQ A;  5KAA A;  1OET A;  3F41 A;  1PTU A;  2I6M A;  1L8G A;  5GTJ A;  2Q05 A;  2NZ6 A;  1PA9 A;  2Y67 A;  1W78 A;  5EHR A;  2VTE A;  1C83 A;  4GE6 A;  4QBE A;  4KYR A;  2JFG A;  4ZRT A;  1I9T A;  2C46 A;  1P15 A;  3S4E A;  2J16 B;  1OHD A;  5KAD A;  4BJO A;  3F9B A;  3H2X A;  1C86 A;  1RPM A;  2XJA A;  1T49 A;  1KAK A;  1G4W R;  2CFV A;  1ZZW A;  1U25 A;  4BUB A;  2B3O A;  1VHR A;  1QXK A;  3AWE A;  3ZM0 A;  2X5O A;  1YGU A;  5K24 A;  4Z6B A;  1Q6S A;  3O4T A;  4OHH A;  2F6W A;  4CVL A;  5K22 A;  1ZC0 A;  2FJN A;  1G1F A;  1C88 A;  2I6I A;  3QCM A;  3NME A;  4NX8 A;  1NZ7 A;  4JBC A;  2ZN7 A;  2F00 A;  4R0S A;  1LYV A;  3BLT A;  5J8R A;  2PI7 A;  2RF6 A;  4NYH A;  4OHD A;  2BV5 A;  1WCH A;  2NT7 A;  5K25 A;  1GG4 A;  1WRM A;  3RO1 A;  5BUG A;  1OHE A;  1RXD A;  2VOS A;  1Q1M A;  4HRF A;  2I5X A;  4QUM A;  3S3E A;  3HN7 A;  2GC6 A;  1ONZ A;  1PTV A;  3LJ8 A;  4KYQ A;  4R30 A;  4DGX A;  1JBW A;  2A8B A;  3V0I A;  1JBV A;  3RZ2 A;  2QDC A;  3ZMP A;  2I75 A;  2CM3 A;  2PSZ A;  2P6X A;  1OEU A;  3LK7 A;  2CMC A;  1G7F A;  2F6F A;  2HC2 A;  2H4G A;  3D42 A;  2CM7 A;  4JMJ A;  4YAA A;  1OHC A;  1XBO A;  1C84 A;  1UAG A;  3QKP A;  4RH5 A;  2Q47 A;  3QCB A;  3BM8 A;  2I6P A;  2CMA A;  2A3K A;  4Y2E A;  5K9W A;  1T48 A;  2J16 A;  2F6Z A;  1MKP A;  4RDD A;  1OEV A;  1XM2 A;  2CNE A;  3ZM3 A;  4YR8 B;  2E0T A;  5KA7 A;  1U24 A;  2OUD A;  3PS5 A;  5KAC A;  2UUP A;  4ZIY A;  3ZV2 A;  1OES A;  3V0F A;  2G59 A;  1LAR A;  4PYH A;  1T4J A;  2NLK A;  4OHI A;  5KA2 A;  4OHE A;  1NWE A;  1FPR A;  2B49 A;  3AWG A;  1PTY A;  1OEO X;  5K9V A;  1JF7 A;  2VEU A;  3N0A A;  2AM2 A;  1BZJ A;  3SR9 A;  1I57 A; 
#chains in the Genus database with same CATH homology
 4WTY A;  2BIJ A;  4RI4 A;  3B7O A;  2B4O A;  3EB1 A;  2I6J A;  1XRI A;  4HJP A;  2QCJ A;  1G1G A;  3V0G A;  2H02 A;  2VEV A;  1YN9 A;  3MMJ A;  2M3V A;  2HY3 A;  2F6V A;  5KAB A;  4RI5 A;  4RKK A;  3QCG A;  1Q6T A;  3ZM1 A;  3O4U A;  2QBR A;  2CJZ A;  1L8K A;  2QEP A;  3F99 A;  2NV5 A;  2OOQ A;  5KA0 A;  4R0T A;  2CNG A;  2YDU A;  1QZ0 A;  1Q6J A;  1NL9 A;  3RGQ A;  2JJD A;  2F71 A;  2NTA A;  2AHS A;  2QBP A;  1BZC A;  2I4E A;  1ZCL A;  2GWO A;  4GFV A;  2P4D A;  2HXP A;  4QAH A;  3AWF A;  3A5J A;  3QCJ A;  4BPC A;  1YZ4 A;  5BZX A;  3EU0 A;  1ECV A;  5KA3 A;  3QCE A;  2I6O A;  2QCT A;  5M43 A;  2Y96 A;  5IBS A;  2DXP A;  1PXH A;  2HCM A;  5BZZ A;  5KA1 A;  3QCF A;  2OZ5 A;  3QCI A;  1M3G A;  3BRH A;  3GXG A;  1C85 A;  2I3U A;  4WU3 A;  1JLN A;  4S0G A;  3F9A A;  1YFO A;  5EHP A;  2BGD A;  3S3F A;  4QAP A;  1XXV A;  3A5K A;  2MBC A;  4I8N A;  2FJM A;  3QCN A;  3S3K A;  2B4P A;  4GRZ A;  4IKC A;  1ZCK A;  2GP0 A;  4D3Q A;  1R6H A;  5I6V A;  3I80 A;  1PYN A;  3O3L A;  2F70 A;  1LQF A;  1G4U S;  1Q6N A;  3GXH A;  3I36 A;  1FPZ A;  2F6Y A;  3OMH A;  4GRY A;  5KA9 A;  1AAX A;  1KAV A;  2CM2 A;  4ZN5 A;  1GWZ A;  2ESB A;  1D5R A;  2NT2 A;  4D3R A;  3CM3 A;  5LXQ B;  1Q6M A;  3S4O A;  2QBS A;  2HVL A;  4NWG A;  1WAX A;  5KA8 A;  2F6T A;  1V3A A;  2BZL A;  2Y2F A;  2H4K A;  1NO6 A;  3EZZ A;  3BLU A;  4NWF A;  4DGP A;  2B4U A;  4MBB A;  2H04 A;  3M4U A;  4GS0 A;  5IBM A;  2I42 A;  1NNY A;  2PA5 A;  4H1O A;  3OLR A;  3F81 A;  2PQ5 A;  1NWL A;  2FH7 A;  3QCC A;  3EAX A;  1ONY A;  1G1H A;  3CWE A;  3S3H A;  3QKQ A;  4WU2 A;  4D3P A;  2CM8 A;  2AZR A;  3MOZ A;  4PVG A;  3U96 A;  5K23 A;  1EEN A;  3D1O A;  3RGO A;  2QDM A;  2B07 A;  1YTW A;  1SUG A;  1XXP A;  3V0D A;  4ERC A;  2BGE A;  1PTT A;  1J4X A;  3SME A;  2J17 A;  4GWF A;  3V0H A;  2I4G A;  2HC1 A;  2ZMM A;  4KI9 A;  1PA1 A;  4HJQ A;  3I7Z A;  2PBN A;  2CNF A;  3MOW A;  1YTS A;  1U26 A;  4JMK A;  4WOH A;  1OEM X;  1YWF A;  2HNP A;  4QBW A;  4OHL A;  4Y14 A;  4QUN A;  2QDP A;  4H34 A;  3V0E A;  1GFY A;  1EEO A;  3D1Q A;  2I4H A;  5KA4 A;  3D44 A;  2HNQ A;  2CMB A;  2I3R A;  3V0J A;  3EMU A;  2SHP A;  1FQ1 A;  4B04 A;  2IMG A;  3QCD A;  4RH9 A;  2C7S A;  2HB1 A;  3O4S A;  1A5Y A;  1YPT A;  2R0B A;  2G6Z A;  3QCK A;  1YTN A;  2WGP A;  3O5X A;  5AWX A;  3D1H A;  5HDE A;  4NND A;  1BZH A;  2CNH A;  2CNI A;  3ZM2 A;  2B4S A;  2VEW A;  4JNB A;  4ICZ A;  5BX1 A;  2H03 A;  4TVV A;  4GE2 A;  2VEY A;  4J51 A;  3D9C A;  3QCL A;  2QBQ A;  1C87 A;  1PH0 A;  1YGR A;  2H4V A;  5MMZ B;  2VEX A;  4ZI4 A;  4RHG A;  2PT0 A;  2F46 A;  4GE5 A;  2I1Y A;  2GJT A;  4AZ1 A;  1Q6P A;  4GFU A;  1G7G A;  3QCH A;  1I9S A;  1X24 A;  2OC3 A;  3ZMQ A;  5KAA A;  1OET A;  3F41 A;  1PTU A;  2I6M A;  1L8G A;  5GTJ A;  2Q05 A;  2NZ6 A;  1PA9 A;  5EHR A;  1C83 A;  4GE6 A;  4QBE A;  4KYR A;  4ZRT A;  1I9T A;  2C46 A;  1P15 A;  3S4E A;  2J16 B;  1OHD A;  5KAD A;  4BJO A;  3F9B A;  3H2X A;  1C86 A;  1RPM A;  1T49 A;  2CFV A;  1KAK A;  1G4W R;  1ZZW A;  1U25 A;  2B3O A;  1VHR A;  1QXK A;  3AWE A;  3ZM0 A;  1YGU A;  5K24 A;  4Z6B A;  1Q6S A;  3O4T A;  4OHH A;  2F6W A;  5K22 A;  1ZC0 A;  2FJN A;  1G1F A;  1C88 A;  2I6I A;  3QCM A;  3NME A;  4NX8 A;  1NZ7 A;  4JBC A;  2ZN7 A;  4R0S A;  1LYV A;  3BLT A;  5J8R A;  2PI7 A;  2RF6 A;  4NYH A;  4OHD A;  2BV5 A;  1WCH A;  2NT7 A;  5K25 A;  1WRM A;  3RO1 A;  5BUG A;  1OHE A;  1RXD A;  1Q1M A;  4HRF A;  2I5X A;  4QUM A;  3S3E A;  1ONZ A;  1PTV A;  3LJ8 A;  4KYQ A;  4R30 A;  4DGX A;  2A8B A;  3V0I A;  3RZ2 A;  2QDC A;  3ZMP A;  2I75 A;  2CM3 A;  2PSZ A;  2P6X A;  1OEU A;  2CMC A;  1G7F A;  2F6F A;  2HC2 A;  2H4G A;  3D42 A;  2CM7 A;  4JMJ A;  4YAA A;  1OHC A;  1XBO A;  1C84 A;  3QKP A;  4RH5 A;  2Q47 A;  3QCB A;  3BM8 A;  2I6P A;  2CMA A;  2A3K A;  4Y2E A;  5K9W A;  1T48 A;  2J16 A;  2F6Z A;  1MKP A;  4RDD A;  1OEV A;  1XM2 A;  2CNE A;  3ZM3 A;  4YR8 B;  2E0T A;  5KA7 A;  1U24 A;  2OUD A;  3PS5 A;  5KAC A;  3ZV2 A;  1OES A;  3V0F A;  2G59 A;  1LAR A;  4PYH A;  1T4J A;  2NLK A;  4OHI A;  5KA2 A;  4OHE A;  1NWE A;  1FPR A;  2B49 A;  3AWG A;  1PTY A;  1OEO X;  5K9V A;  1JF7 A;  2VEU A;  3N0A A;  1BZJ A;  3SR9 A;  1I57 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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