1P9PA

The crystal structure of a m1g37 trna methyltransferase, trmd
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
Knots found
sequence length
246
structure length
235
Chain Sequence
MWIGIISLFPEMFRAITDYGVTGRAVKNGLLSIQSWSPRDFTHDRHRTVDDRPYGGGPGMLMMVQPLRDAIHAAKAAAGEGAKVIYLSPQGRKLDQAGVSELATNQKLILVCGRYEGIDERVIQTEIDEEWSIGDYVLSGGELPAMTLIDSVSRFIPGVLGEGLLDCPHYTRPEVLEGMEVPPVLLSGNHAEIRRWRLKQSLGRTWLRRPELLENLALTEEQARLLAEFKTEHAQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Insights into Catalysis by a Knotted TrmD tRNA Methyltransferase.
pubmed doi rcsb
molecule keywords tRNA (Guanine-N(1)-)-methyltransferase
molecule tags Transferase
source organism Escherichia coli
total genus 67
structure length 235
sequence length 246
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2003-05-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 1p9pA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 1p9pA01
3NK6A 2O3AA 1J85A 4MCCA 3ILKA 4YQKA 5GM8A 4J3CA 3KY7A 4X3MA 3AXZA 4YQ6A 4YQSA 2CX8A 4YQGA 4YQNA 3N4JA 4CNDA 4YQQA 4CNEA 4XBOA 2EGWA 4YQJA 4KGNA 5FAIA 5GMCA 1NS5A 3GYQA 4MCBA 4KDZA 1X7PA 4YQ9A 3AIAA 1VHKA 3NK7A 1P9PA 1UALA 1MXIA 1OY5A 4YQRA 4YVJA 4PZKA 3QUVA 4L69A 1UAJA 2I6DA 1UAKA 2YY8A 4YQ0A 1TO0A 2V3KA 4YVKA 4IG6A 3N4KA 3OINA 3OIJA 4YPWA 2Z0YA 5GMBA 4YVHA 4YQDA 3DCMX 3AI9X 5CO4A 4YPZA 1ZJRA 3E5YA 4YQCA 4YQ3A 3BBEA 4RG1A 4MCDA 1NXZA 4YQ1A 1K3RA 2QWVA 4YQBA 4YQ2A 1Z85A 3IC6A 1IPAA 3O7BA 4H3YA 4H3ZA 1V6ZA 5D9FA 3L8UA 1VHYA 1UAMA 3BBHA 3BBDA 4YQ7A 4YQ8A 4YQAA 2HA8A 3KNUA 4CNGA 3KW2A 1V2XA 4YPXA 4YQPA 2EGVA 3KTYA 4YQ4A 1GZ0A 4YQLA 4X3LA 4FAKA 2QMMA 1X7OA 3ONPA 1VH0A 4YQ5A 4YQOA 2V3JA 4CNFA 1O6DA 4YQIA 4YPYA 3IEFA 4JALA 4YVIA 3OIIA 4YVGA 4JAKA 4E8BA 4YQTA
chains in the Genus database with same CATH superfamily
3NK6A 2O3AA 1J85A 4MCCA 3ILKA 4YQKA 5GM8A 4J3CA 3KY7A 4JWFA 4X3MA 3AXZA 4FMWA 1JHGA 1MI7R 4YQ6A 3G1CA 4JWJA 4YQSA 2CX8A 3KORA 1WRPR 4YQGA 4YQNA 3N4JA 4CNDA 4YQQA 4CNEA 4XBOA 2EGWA 4YQJA 4KGNA 5FAIA 5GMCA 1NS5A 1TROA 3GYQA 4MCBA 4JWGA 4KDZA 3SSWN 1X7PA 4YQ9A 3AIAA 1VHKA 3NK7A 1P9PA 1UALA 1MXIA 1OY5A 4YQRA 1CO0A 4YVJA 4PZKA 3QUVA 1TRRA 4JWHA 4L69A 1UAJA 1RCSA 2I6DA 1ZT9A 1UAKA 2YY8A 4YQ0A 1WRTR 1TO0A 2V3KA 4YVKA 4IG6A 3N4KA 3OINA 3OIJA 4YPWA 2Z0YA 5GMBA 4YVHA 4YQDA 3DCMX 3AI9X 5CO4A 4YPZA 1ZJRA 3E5YA 4YQCA 4YQ3A 3BBEA 4RG1A 3SSXN 4MCDA 1NXZA 4YQ1A 1K3RA 2QWVA 4YQBA 1WRSR 4YQ2A 1Z85A 3IC6A 1IPAA 3O7BA 2XDIA 4H3YA 4H3ZA 1V6ZA 5D9FA 3L8UA 1VHYA 3WRPA 1UAMA 2OZ9R 3FRWA 3BBHA 3BBDA 4YQ7A 4YQ8A 4YQAA 2HA8A 3KNUA 4CNGA 3KW2A 1V2XA 4YPXA 4YQPA 2EGVA 3KTYA 4YQ4A 1GZ0A 4YQLA 4X3LA 4FAKA 2QMMA 1X7OA 3ONPA 1VH0A 4YQ5A 4YQOA 2V3JA 4CNFA 1O6DA 4YQIA 4YPYA 3IEFA 4JALA 4YVIA 3OIIA 4YVGA 4JAKA 4E8BA 4YQTA
chains in the Genus database with same CATH topology
3NK6A 2O3AA 1J85A 4MCCA 3ILKA 4YQKA 5GM8A 4J3CA 3KY7A 4JWFA 4X3MA 3AXZA 4FMWA 4YQ6A 4JWJA 4YQSA 2CX8A 4YQGA 4YQNA 3N4JA 4CNDA 4YQQA 4CNEA 4XBOA 2EGWA 4YQJA 4KGNA 5FAIA 5GMCA 1NS5A 3GYQA 4MCBA 4JWGA 4KDZA 1X7PA 4YQ9A 3AIAA 1VHKA 3NK7A 1P9PA 1UALA 1MXIA 1OY5A 4YQRA 4YVJA 4PZKA 3QUVA 4JWHA 4L69A 1UAJA 2I6DA 1UAKA 2YY8A 4YQ0A 1TO0A 2V3KA 4YVKA 4IG6A 3N4KA 3OINA 3OIJA 4YPWA 2Z0YA 5GMBA 4YVHA 4YQDA 3DCMX 3AI9X 5CO4A 4YPZA 1ZJRA 3E5YA 4YQCA 4YQ3A 3BBEA 4RG1A 4MCDA 1NXZA 4YQ1A 1K3RA 2QWVA 4YQBA 4YQ2A 1Z85A 3IC6A 1IPAA 3O7BA 4H3YA 4H3ZA 1V6ZA 5D9FA 3L8UA 1VHYA 1UAMA 3BBHA 3BBDA 4YQ7A 4YQ8A 4YQAA 2HA8A 3KNUA 4CNGA 3KW2A 1V2XA 4YPXA 4YQPA 2EGVA 3KTYA 4YQ4A 1GZ0A 4YQLA 4X3LA 4FAKA 2QMMA 1X7OA 3ONPA 1VH0A 4YQ5A 4YQOA 2V3JA 4CNFA 1O6DA 4YQIA 4YPYA 3IEFA 4JALA 4YVIA 3OIIA 4YVGA 4JAKA 4E8BA 4YQTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3NK6 A;  2O3A A;  1J85 A;  4MCC A;  3ILK A;  4YQK A;  5GM8 A;  4J3C A;  3KY7 A;  4X3M A;  3AXZ A;  4YQ6 A;  4YQS A;  2CX8 A;  4YQG A;  4YQN A;  3N4J A;  4CND A;  4YQQ A;  4CNE A;  4XBO A;  2EGW A;  4YQJ A;  4KGN A;  5FAI A;  5GMC A;  1NS5 A;  3GYQ A;  4MCB A;  4KDZ A;  1X7P A;  4YQ9 A;  3AIA A;  1VHK A;  3NK7 A;  1P9P A;  1UAL A;  1MXI A;  1OY5 A;  4YQR A;  4YVJ A;  4PZK A;  3QUV A;  4L69 A;  1UAJ A;  2I6D A;  1UAK A;  2YY8 A;  4YQ0 A;  1TO0 A;  2V3K A;  4YVK A;  4IG6 A;  3N4K A;  3OIN A;  3OIJ A;  4YPW A;  2Z0Y A;  5GMB A;  4YVH A;  4YQD A;  3DCM X;  3AI9 X;  5CO4 A;  4YPZ A;  1ZJR A;  3E5Y A;  4YQC A;  4YQ3 A;  3BBE A;  4RG1 A;  4MCD A;  1NXZ A;  4YQ1 A;  1K3R A;  2QWV A;  4YQB A;  4YQ2 A;  1Z85 A;  3IC6 A;  1IPA A;  3O7B A;  4H3Y A;  4H3Z A;  1V6Z A;  5D9F A;  3L8U A;  1VHY A;  1UAM A;  3BBH A;  3BBD A;  4YQ7 A;  4YQ8 A;  4YQA A;  2HA8 A;  3KNU A;  4CNG A;  3KW2 A;  1V2X A;  4YPX A;  4YQP A;  2EGV A;  3KTY A;  4YQ4 A;  1GZ0 A;  4YQL A;  4X3L A;  4FAK A;  2QMM A;  1X7O A;  3ONP A;  1VH0 A;  4YQ5 A;  4YQO A;  2V3J A;  4CNF A;  1O6D A;  4YQI A;  4YPY A;  3IEF A;  4JAL A;  4YVI A;  3OII A;  4YVG A;  4JAK A;  4E8B A;  4YQT A; 
#chains in the Genus database with same CATH topology
 3NK6 A;  2O3A A;  1J85 A;  4MCC A;  3ILK A;  4YQK A;  5GM8 A;  4J3C A;  3KY7 A;  4JWF A;  4X3M A;  3AXZ A;  4FMW A;  1JHG A;  1MI7 R;  4YQ6 A;  3G1C A;  4JWJ A;  4YQS A;  2CX8 A;  3KOR A;  1WRP R;  4YQG A;  4YQN A;  3N4J A;  4CND A;  4YQQ A;  4CNE A;  4XBO A;  2EGW A;  4YQJ A;  4KGN A;  5FAI A;  5GMC A;  1NS5 A;  1TRO A;  3GYQ A;  4MCB A;  4JWG A;  4KDZ A;  3SSW N;  1X7P A;  4YQ9 A;  3AIA A;  1VHK A;  3NK7 A;  1P9P A;  1UAL A;  1MXI A;  1OY5 A;  4YQR A;  1CO0 A;  4YVJ A;  4PZK A;  3QUV A;  1TRR A;  4JWH A;  4L69 A;  1UAJ A;  1RCS A;  2I6D A;  1ZT9 A;  1UAK A;  2YY8 A;  4YQ0 A;  1WRT R;  1TO0 A;  2V3K A;  4YVK A;  4IG6 A;  3N4K A;  3OIN A;  3OIJ A;  4YPW A;  2Z0Y A;  5GMB A;  4YVH A;  4YQD A;  3DCM X;  3AI9 X;  5CO4 A;  4YPZ A;  1ZJR A;  3E5Y A;  4YQC A;  4YQ3 A;  3BBE A;  4RG1 A;  3SSX N;  4MCD A;  1NXZ A;  4YQ1 A;  1K3R A;  2QWV A;  4YQB A;  1WRS R;  4YQ2 A;  1Z85 A;  3IC6 A;  1IPA A;  3O7B A;  2XDI A;  4H3Y A;  4H3Z A;  1V6Z A;  5D9F A;  3L8U A;  1VHY A;  3WRP A;  1UAM A;  2OZ9 R;  3FRW A;  3BBH A;  3BBD A;  4YQ7 A;  4YQ8 A;  4YQA A;  2HA8 A;  3KNU A;  4CNG A;  3KW2 A;  1V2X A;  4YPX A;  4YQP A;  2EGV A;  3KTY A;  4YQ4 A;  1GZ0 A;  4YQL A;  4X3L A;  4FAK A;  2QMM A;  1X7O A;  3ONP A;  1VH0 A;  4YQ5 A;  4YQO A;  2V3J A;  4CNF A;  1O6D A;  4YQI A;  4YPY A;  3IEF A;  4JAL A;  4YVI A;  3OII A;  4YVG A;  4JAK A;  4E8B A;  4YQT A; 
#chains in the Genus database with same CATH homology
 3NK6 A;  2O3A A;  1J85 A;  4MCC A;  3ILK A;  4YQK A;  5GM8 A;  4J3C A;  3KY7 A;  4JWF A;  4X3M A;  3AXZ A;  4FMW A;  4YQ6 A;  4JWJ A;  4YQS A;  2CX8 A;  4YQG A;  4YQN A;  3N4J A;  4CND A;  4YQQ A;  4CNE A;  4XBO A;  2EGW A;  4YQJ A;  4KGN A;  5FAI A;  5GMC A;  1NS5 A;  3GYQ A;  4MCB A;  4JWG A;  4KDZ A;  1X7P A;  4YQ9 A;  3AIA A;  1VHK A;  3NK7 A;  1P9P A;  1UAL A;  1MXI A;  1OY5 A;  4YQR A;  4YVJ A;  4PZK A;  3QUV A;  4JWH A;  4L69 A;  1UAJ A;  2I6D A;  1UAK A;  2YY8 A;  4YQ0 A;  1TO0 A;  2V3K A;  4YVK A;  4IG6 A;  3N4K A;  3OIN A;  3OIJ A;  4YPW A;  2Z0Y A;  5GMB A;  4YVH A;  4YQD A;  3DCM X;  3AI9 X;  5CO4 A;  4YPZ A;  1ZJR A;  3E5Y A;  4YQC A;  4YQ3 A;  3BBE A;  4RG1 A;  4MCD A;  1NXZ A;  4YQ1 A;  1K3R A;  2QWV A;  4YQB A;  4YQ2 A;  1Z85 A;  3IC6 A;  1IPA A;  3O7B A;  4H3Y A;  4H3Z A;  1V6Z A;  5D9F A;  3L8U A;  1VHY A;  1UAM A;  3BBH A;  3BBD A;  4YQ7 A;  4YQ8 A;  4YQA A;  2HA8 A;  3KNU A;  4CNG A;  3KW2 A;  1V2X A;  4YPX A;  4YQP A;  2EGV A;  3KTY A;  4YQ4 A;  1GZ0 A;  4YQL A;  4X3L A;  4FAK A;  2QMM A;  1X7O A;  3ONP A;  1VH0 A;  4YQ5 A;  4YQO A;  2V3J A;  4CNF A;  1O6D A;  4YQI A;  4YPY A;  3IEF A;  4JAL A;  4YVI A;  3OII A;  4YVG A;  4JAK A;  4E8B A;  4YQT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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