1PA1A

Crystal structure of the c215d mutant of protein tyrosine phosphatase 1b
Total Genus 113
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
113
sequence length
302
structure length
302
Chain Sequence
KLEFMEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHDSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHED
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Functional characterization and crystal structure of the C215D mutant of protein-tyrosine phosphatase-1B
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Protein-tyrosine phosphatase, non-receptor type 1
total genus 113
structure length 302
sequence length 302
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2003-05-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 1pa1A00
5EHRA 1G7FA 1Q6MA 1LARA 3ZM0A 2P4DA 1J4XA 2QCJA 3V0HA 1G4WR 3V0IA 3QCHA 4OHEA 1KAKA 4DGPA 5BUGA 3ZM3A 1RPMA 2DXPA 2G6ZA 3EU0A 3F9AA 2GWOA 3RO1A 5KA0A 3M4UA 4IKCA 4Y14A 5IBSA 1PTYA 3F41A 1OEUA 1OHDA 2C46A 2I1YA 3D42A 1NL9A 4D3RA 5BZXA 2P6XA 2ZMMA 2G59A 2I4GA 1Q1MA 3F9BA 3S3KA 1G4US 3QKQA 2CMBA 1XM2A 4GS0A 1NO6A 2BV5A 4GFUA 3QCEA 4R30A 3QCLA 3MMJA 5KAAA 5LXQB 5KACA 4H1OA 2VEUA 2A8BA 4B04A 5KA2A 2VEXA 4ZRTA 5K9VA 4HJPA 4ERCA 4GRYA 3A5JA 4Y2EA 2GP0A 2I6PA 2NT2A 1G1GA 1YN9A 1OEVA 4Z6BA 1T48A 4JMJA 2J17A 2J16A 4GE5A 2CNEA 3RGOA 2CNIA 3I7ZA 3ZM2A 1C88A 2CM8A 1G7GA 2B4UA 2QCTA 2FH7A 1A5YA 4R0TA 5K25A 4GWFA 4WU3A 3S3EA 3D1HA 3BLTA 2HC1A 3PS5A 1U24A 4NWGA 1BZHA 4QAPA 1Q6SA 3NMEA 4WU2A 2PI7A 5AWXA 4YR8B 1SUGA 1QZ0A 4QAHA 4JBCA 1YPTA 2I6IA 4R0SA 5J8RA 3MOWA 1WCHA 1L8KA 2CMAA 4GE2A 2B07A 1EEOA 2BGEA 1PTTA 1ZCKA 2OOQA 1ZC0A 2QDCA 3OLRA 1P15A 2B3OA 2I3UA 4RI5A 4OHDA 2OC3A 4MBBA 5BZZA 5MMZB 5KA9A 3QCGA 2CNFA 4GE6A 4PYHA 1OHEA 1PA9A 4RH5A 1XBOA 1C83A 2CNHA 3BRHA 2OZ5A 2QBSA 2Q05A 3D9CA 4RI4A 5I6VA 4AZ1A 3EAXA 2QBPA 2IMGA 1LYVA 5GTJA 2QBRA 1PH0A 5KADA 1BZJA 2CM7A 3RZ2A 3GXHA 1OETA 1YTSA 1C86A 2I4HA 4NYHA 1R6HA 1WRMA 3ZM1A 1MKPA 4HJQA 3EB1A 1C84A 3SR9A 2SHPA 1G1HA 3V0FA 2I5XA 1YFOA 2F70A 3AWEA 3LJ8A 3O4SA 4NNDA 4KYQA 3S4OA 5KABA 2JJDA 3N0AA 2B49A 2F71A 2NV5A 4KI9A 4OHLA 1ZZWA 1YGUA 2CM2A 3A5KA 1XRIA 3D1QA 4JMKA 3QCCA 3QCKA 2F6TA 1D5RA 2QDPA 4D3QA 4D3PA 2A3KA 2I75A 3I80A 3B7OA 2HB1A 1V3AA 2E0TA 1NWEA 3QKPA 1I9SA 1EENA 1JF7A 5KA8A 3EMUA 1I9TA 1Q6PA 4H34A 2H4VA 2HY3A 3I36A 1NNYA 1PA1A 2VEVA 2F6WA 3F81A 2I3RA 3ZMPA 2PT0A 2CJZA 2HCMA 1PYNA 5BX1A 4GFVA 4NWFA 1NWLA 2F6ZA 1PXHA 3S3HA 3QCBA 5M43A 4PVGA 2I6JA 3AWGA 2PA5A 1G1FA 3H2XA 5K9WA 4I8NA 3QCDA 4JNBA 1YZ4A 4GRZA 1C87A 1YGRA 2PBNA 5KA1A 1I57A 3U96A 3S3FA 3AWFA 2B4PA 1C85A 1JLNA 1FQ1A 2HNPA 2BGDA 3GXGA 2NT7A 4KYRA 3QCNA 5EHPA 1GWZA 2FJMA 3V0EA 2CM3A 1YTWA 2Y96A 3D44A 3S4EA 4YAAA 1T49A 3D1OA 2I4EA 3O3LA 2H4GA 3ZMQA 5K23A 2HXPA 3V0JA 2M3VA 2F6FA 2NLKA 2Q47A 1Q6NA 5KA7A 1KAVA 1U25A 1ONZA 4OHIA 3V0DA 1YWFA 1ECVA 3QCMA 2RF6A 1NZ7A 1ZCLA 2NZ6A 3CWEA 1QXKA 3EZZA 2B4SA 2C7SA 2F6YA 1OESA 2H02A 5KA3A 2I6MA 2F6VA 4BJOA 2AHSA 2YDUA 2B4OA 2PSZA 4WTYA 2GJTA 2BZLA 2CMCA 4J51A 3QCIA 2QDMA 4QUMA 3ZV2A 2H04A 3O4UA 2HNQA 2R0BA 2QBQA 3O4TA 1Q6TA 2FJNA 3F99A 4ZN5A 4S0GA 5HDEA 1OHCA 1PTUA 5K22A 2ESBA 2BIJA 2F46A 2NTAA 4TVVA 1OEOX 2VEYA 4BPCA 2PQ5A 1RXDA 2CNGA 3SMEA 5IBMA 1M3GA 2MBCA 3BLUA 4DGXA 3CM3A 5K24A 2CFVA 1X24A 1YTNA 3RGQA 1FPRA 3O5XA 1Q6JA 2VEWA 1VHRA 1LQFA 1XXPA 1XXVA 2H4KA 4OHHA 2H03A 1AAXA 2HC2A 2Y2FA 4QUNA 3BM8A 2I6OA 2ZN7A 1L8GA 4ICZA 3QCFA 2QEPA 1FPZA 4RH9A 1OEMX 2I42A 1BZCA 4RKKA 4ZI4A 1T4JA 2J16B 1WAXA 4NX8A 2AZRA 1ONYA 4RHGA 3V0GA 4RDDA 3QCJA 3MOZA 2WGPA 3OMHA 5KA4A 2HVLA 4WOHA 2OUDA 4QBEA 4HRFA 1PTVA 4QBWA 1GFYA 1U26A
chains in the Genus database with same CATH superfamily
5EHRA 1G7FA 1Q6MA 1LARA 3ZM0A 2P4DA 1J4XA 2QCJA 3V0HA 1G4WR 3V0IA 3QCHA 4OHEA 1KAKA 4DGPA 5BUGA 3ZM3A 4ZIYA 1RPMA 2DXPA 2G6ZA 3EU0A 3F9AA 1P31A 2GWOA 3RO1A 5KA0A 3M4UA 4IKCA 4Y14A 5IBSA 1PTYA 3F41A 1OEUA 1OHDA 2C46A 2I1YA 3D42A 1NL9A 4D3RA 5BZXA 2X5OA 2P6XA 2ZMMA 2G59A 2I4GA 1Q1MA 3F9BA 3S3KA 1G4US 3QKQA 2CMBA 1XM2A 4GS0A 2JFFA 1NO6A 2BV5A 4GFUA 3QCEA 3ZM6A 4R30A 3QCLA 3MMJA 5KAAA 2JFGA 5LXQB 5KACA 4H1OA 2VEUA 2A8BA 4B04A 5KA2A 2VEXA 4ZRTA 5K9VA 4HJPA 4ERCA 4GRYA 3A5JA 4Y2EA 2GP0A 2I6PA 2NT2A 1G1GA 1YN9A 1OEVA 4Z6BA 1FGSA 1T48A 4JMJA 2J17A 1GQQA 2J16A 4GE5A 1J6UA 2CNEA 4C13A 3RGOA 1E0DA 2CNIA 4BUCA 3I7ZA 3ZM2A 1C88A 2CM8A 1G7GA 2B4UA 2QCTA 2FH7A 1A5YA 4R0TA 5K25A 4GWFA 4WU3A 3S3EA 3D1HA 3BLTA 2HC1A 3PS5A 3N2AA 1U24A 4NWGA 2UUOA 1BZHA 4QAPA 1Q6SA 3NMEA 4WU2A 2PI7A 5AWXA 4YR8B 1SUGA 1QZ0A 4QAHA 4JBCA 1YPTA 2I6IA 4R0SA 5J8RA 3MOWA 1WCHA 1L8KA 2CMAA 4GE2A 2B07A 1EEOA 2BGEA 1PTTA 2Y66A 1ZCKA 2OOQA 1ZC0A 2QDCA 3OLRA 3UAGA 1P15A 2B3OA 2I3UA 4RI5A 4OHDA 2OC3A 4MBBA 5BZZA 1JBVA 1W7KA 5MMZB 4CVLA 5KA9A 4CVKA 3QCGA 2CNFA 4GE6A 4PYHA 1OHEA 2JFHA 1PA9A 1EEHA 4RH5A 1XBOA 1C83A 2CNHA 3BRHA 2OZ5A 2QBSA 2Q05A 3D9CA 4RI4A 5I6VA 4AZ1A 3EAXA 2QBPA 2IMGA 1LYVA 5GTJA 2QBRA 1PH0A 4CVMA 5KADA 1BZJA 2CM7A 3RZ2A 3GXHA 1OETA 1E8CA 1YTSA 1C86A 2I4HA 4NYHA 2WTZA 3ZM5A 1R6HA 1WRMA 3ZL8A 3ZM1A 1MKPA 4HJQA 3EB1A 5A5EA 2Y68A 1C84A 2Y1OA 3SR9A 2SHPA 1G1HA 3V0FA 2I5XA 1YFOA 2F70A 3AWEA 3LJ8A 3O4SA 4NNDA 2VTDA 4KYQA 3S4OA 5KABA 2JJDA 3N0AA 2B49A 2F71A 2NV5A 4C12A 4KI9A 4OHLA 1ZZWA 1JBWA 1YGUA 2CM2A 3A5KA 1XRIA 3D1QA 4JMKA 3QCCA 1UAGA 3QCKA 2F6TA 1D5RA 2QDPA 4D3QA 4D3PA 2A3KA 2I75A 3I80A 3B7OA 2HB1A 1V3AA 2E0TA 1NWEA 3QKPA 1I9SA 1EENA 1JF7A 5KA8A 3EMUA 1I9TA 1Q6PA 4H34A 2H4VA 2HY3A 3I36A 1NNYA 1PA1A 2VEVA 2F6WA 2VTEA 3F81A 2I3RA 3ZMPA 4BUBA 2PT0A 2CJZA 2HCMA 1PYNA 5BX1A 3PYZA 4GFVA 4NWFA 1NWLA 2F6ZA 1PXHA 3S3HA 3QCBA 5M43A 4PVGA 1O5ZA 2I6JA 1P3DA 3AWGA 2PA5A 1G1FA 3H2XA 5K9WA 4I8NA 3QCDA 4JNBA 4QF5A 1YZ4A 4GRZA 1C87A 1YGRA 2PBNA 5KA1A 1I57A 3U96A 2XPCA 3S3FA 3AWFA 2B4PA 1C85A 1JLNA 1FQ1A 2HNPA 2BGDA 3GXGA 2NT7A 4KYRA 3QCNA 5EHPA 1GWZA 2FJMA 3V0EA 2GCAA 2CM3A 2Y67A 1YTWA 1W78A 2Y96A 3D44A 3S4EA 4YAAA 1T49A 3D1OA 2I4EA 3O3LA 2H4GA 2GC5A 3ZMQA 5K23A 2VORA 2HXPA 3V0JA 2GCBA 2M3VA 2F00A 2F6FA 2NLKA 2Q47A 1Q6NA 5KA7A 2AM2A 1KAVA 1U25A 1ONZA 4OHIA 3V0DA 2XJAA 1YWFA 1ECVA 3QCMA 2RF6A 2UAGA 1NZ7A 1ZCLA 2NZ6A 3CWEA 1QXKA 3EZZA 2B4SA 1GG4A 2C7SA 2F6YA 1OESA 2H02A 5KA3A 2I6MA 2F6VA 4BJOA 3QCZA 2AHSA 3HN7A 2YDUA 2UUPA 2B4OA 2PSZA 4WTYA 2GJTA 2BZLA 2CMCA 4J51A 3QCIA 2QDMA 4QUMA 3ZV2A 2H04A 3O4UA 2HNQA 2R0BA 2QBQA 3O4TA 1Q6TA 2FJNA 3F99A 4ZN5A 4S0GA 5HDEA 1OHCA 1PTUA 5K22A 2ESBA 2BIJA 2F46A 2NTAA 4TVVA 3NRSA 1OEOX 2VEYA 2GC6A 4BPCA 2PQ5A 1RXDA 2CNGA 3SMEA 5IBMA 1M3GA 2MBCA 3BLUA 4DGXA 3CM3A 5K24A 2CFVA 1X24A 1YTNA 3RGQA 1FPRA 3O5XA 1Q6JA 2VEWA 1VHRA 1LQFA 1XXPA 1XXVA 2H4KA 2VOSA 4OHHA 2H03A 1AAXA 2HC2A 2Y2FA 4QUNA 4HV4A 3BM8A 3LK7A 2I6OA 2ZN7A 1L8GA 4ICZA 3QCFA 2WJPA 2QEPA 1FPZA 4RH9A 1OEMX 2I42A 5A5FA 1BZCA 4UAGA 4RKKA 4QDIA 4ZI4A 1T4JA 2J16B 1WAXA 4NX8A 1GQYA 2AZRA 1ONYA 4RHGA 3V0GA 4RDDA 3QCJA 3MOZA 2WGPA 3OMHA 5KA4A 2HVLA 4WOHA 3MVNA 2OUDA 4QBEA 4HRFA 2AM1A 1PTVA 4QBWA 1GFYA 1U26A
chains in the Genus database with same CATH topology
5EHRA 1G7FA 1Q6MA 1LARA 3ZM0A 2P4DA 1J4XA 2QCJA 3V0HA 1G4WR 3V0IA 3QCHA 4OHEA 1KAKA 4DGPA 5BUGA 3ZM3A 1RPMA 2DXPA 2G6ZA 3EU0A 3F9AA 2GWOA 3RO1A 5KA0A 3M4UA 4IKCA 4Y14A 5IBSA 1PTYA 3F41A 1OEUA 1OHDA 2C46A 2I1YA 3D42A 1NL9A 4D3RA 5BZXA 2P6XA 2ZMMA 2G59A 2I4GA 1Q1MA 3F9BA 3S3KA 1G4US 3QKQA 2CMBA 1XM2A 4GS0A 1NO6A 2BV5A 4GFUA 3QCEA 4R30A 3QCLA 3MMJA 5KAAA 5LXQB 5KACA 4H1OA 2VEUA 2A8BA 4B04A 5KA2A 2VEXA 4ZRTA 5K9VA 4HJPA 4ERCA 4GRYA 3A5JA 4Y2EA 2GP0A 2I6PA 2NT2A 1G1GA 1YN9A 1OEVA 4Z6BA 1T48A 4JMJA 2J17A 2J16A 4GE5A 2CNEA 3RGOA 2CNIA 3I7ZA 3ZM2A 1C88A 2CM8A 1G7GA 2B4UA 2QCTA 2FH7A 1A5YA 4R0TA 5K25A 4GWFA 4WU3A 3S3EA 3D1HA 3BLTA 2HC1A 3PS5A 1U24A 4NWGA 1BZHA 4QAPA 1Q6SA 3NMEA 4WU2A 2PI7A 5AWXA 4YR8B 1SUGA 1QZ0A 4QAHA 4JBCA 1YPTA 2I6IA 4R0SA 5J8RA 3MOWA 1WCHA 1L8KA 2CMAA 4GE2A 2B07A 1EEOA 2BGEA 1PTTA 1ZCKA 2OOQA 1ZC0A 2QDCA 3OLRA 1P15A 2B3OA 2I3UA 4RI5A 4OHDA 2OC3A 4MBBA 5BZZA 5MMZB 5KA9A 3QCGA 2CNFA 4GE6A 4PYHA 1OHEA 1PA9A 4RH5A 1XBOA 1C83A 2CNHA 3BRHA 2OZ5A 2QBSA 2Q05A 3D9CA 4RI4A 5I6VA 4AZ1A 3EAXA 2QBPA 2IMGA 1LYVA 5GTJA 2QBRA 1PH0A 5KADA 1BZJA 2CM7A 3RZ2A 3GXHA 1OETA 1YTSA 1C86A 2I4HA 4NYHA 1R6HA 1WRMA 3ZM1A 1MKPA 4HJQA 3EB1A 1C84A 3SR9A 2SHPA 1G1HA 3V0FA 2I5XA 1YFOA 2F70A 3AWEA 3LJ8A 3O4SA 4NNDA 4KYQA 3S4OA 5KABA 2JJDA 3N0AA 2B49A 2F71A 2NV5A 4KI9A 4OHLA 1ZZWA 1YGUA 2CM2A 3A5KA 1XRIA 3D1QA 4JMKA 3QCCA 3QCKA 2F6TA 1D5RA 2QDPA 4D3QA 4D3PA 2A3KA 2I75A 3I80A 3B7OA 2HB1A 1V3AA 2E0TA 1NWEA 3QKPA 1I9SA 1EENA 1JF7A 5KA8A 3EMUA 1I9TA 1Q6PA 4H34A 2H4VA 2HY3A 3I36A 1NNYA 1PA1A 2VEVA 2F6WA 3F81A 2I3RA 3ZMPA 2PT0A 2CJZA 2HCMA 1PYNA 5BX1A 4GFVA 4NWFA 1NWLA 2F6ZA 1PXHA 3S3HA 3QCBA 5M43A 4PVGA 2I6JA 3AWGA 2PA5A 1G1FA 3H2XA 5K9WA 4I8NA 3QCDA 4JNBA 1YZ4A 4GRZA 1C87A 1YGRA 2PBNA 5KA1A 1I57A 3U96A 3S3FA 3AWFA 2B4PA 1C85A 1JLNA 1FQ1A 2HNPA 2BGDA 3GXGA 2NT7A 4KYRA 3QCNA 5EHPA 1GWZA 2FJMA 3V0EA 2CM3A 1YTWA 2Y96A 3D44A 3S4EA 4YAAA 1T49A 3D1OA 2I4EA 3O3LA 2H4GA 3ZMQA 5K23A 2HXPA 3V0JA 2M3VA 2F6FA 2NLKA 2Q47A 1Q6NA 5KA7A 1KAVA 1U25A 1ONZA 4OHIA 3V0DA 1YWFA 1ECVA 3QCMA 2RF6A 1NZ7A 1ZCLA 2NZ6A 3CWEA 1QXKA 3EZZA 2B4SA 2C7SA 2F6YA 1OESA 2H02A 5KA3A 2I6MA 2F6VA 4BJOA 2AHSA 2YDUA 2B4OA 2PSZA 4WTYA 2GJTA 2BZLA 2CMCA 4J51A 3QCIA 2QDMA 4QUMA 3ZV2A 2H04A 3O4UA 2HNQA 2R0BA 2QBQA 3O4TA 1Q6TA 2FJNA 3F99A 4ZN5A 4S0GA 5HDEA 1OHCA 1PTUA 5K22A 2ESBA 2BIJA 2F46A 2NTAA 4TVVA 1OEOX 2VEYA 4BPCA 2PQ5A 1RXDA 2CNGA 3SMEA 5IBMA 1M3GA 2MBCA 3BLUA 4DGXA 3CM3A 5K24A 2CFVA 1X24A 1YTNA 3RGQA 1FPRA 3O5XA 1Q6JA 2VEWA 1VHRA 1LQFA 1XXPA 1XXVA 2H4KA 4OHHA 2H03A 1AAXA 2HC2A 2Y2FA 4QUNA 3BM8A 2I6OA 2ZN7A 1L8GA 4ICZA 3QCFA 2QEPA 1FPZA 4RH9A 1OEMX 2I42A 1BZCA 4RKKA 4ZI4A 1T4JA 2J16B 1WAXA 4NX8A 2AZRA 1ONYA 4RHGA 3V0GA 4RDDA 3QCJA 3MOZA 2WGPA 3OMHA 5KA4A 2HVLA 4WOHA 2OUDA 4QBEA 4HRFA 1PTVA 4QBWA 1GFYA 1U26A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5EHR A;  1G7F A;  1Q6M A;  1LAR A;  3ZM0 A;  2P4D A;  1J4X A;  2QCJ A;  3V0H A;  1G4W R;  3V0I A;  3QCH A;  4OHE A;  1KAK A;  4DGP A;  5BUG A;  3ZM3 A;  1RPM A;  2DXP A;  2G6Z A;  3EU0 A;  3F9A A;  2GWO A;  3RO1 A;  5KA0 A;  3M4U A;  4IKC A;  4Y14 A;  5IBS A;  1PTY A;  3F41 A;  1OEU A;  1OHD A;  2C46 A;  2I1Y A;  3D42 A;  1NL9 A;  4D3R A;  5BZX A;  2P6X A;  2ZMM A;  2G59 A;  2I4G A;  1Q1M A;  3F9B A;  3S3K A;  1G4U S;  3QKQ A;  2CMB A;  1XM2 A;  4GS0 A;  1NO6 A;  2BV5 A;  4GFU A;  3QCE A;  4R30 A;  3QCL A;  3MMJ A;  5KAA A;  5LXQ B;  5KAC A;  4H1O A;  2VEU A;  2A8B A;  4B04 A;  5KA2 A;  2VEX A;  4ZRT A;  5K9V A;  4HJP A;  4ERC A;  4GRY A;  3A5J A;  4Y2E A;  2GP0 A;  2I6P A;  2NT2 A;  1G1G A;  1YN9 A;  1OEV A;  4Z6B A;  1T48 A;  4JMJ A;  2J17 A;  2J16 A;  4GE5 A;  2CNE A;  3RGO A;  2CNI A;  3I7Z A;  3ZM2 A;  1C88 A;  2CM8 A;  1G7G A;  2B4U A;  2QCT A;  2FH7 A;  1A5Y A;  4R0T A;  5K25 A;  4GWF A;  4WU3 A;  3S3E A;  3D1H A;  3BLT A;  2HC1 A;  3PS5 A;  1U24 A;  4NWG A;  1BZH A;  4QAP A;  1Q6S A;  3NME A;  4WU2 A;  2PI7 A;  5AWX A;  4YR8 B;  1SUG A;  1QZ0 A;  4QAH A;  4JBC A;  1YPT A;  2I6I A;  4R0S A;  5J8R A;  3MOW A;  1WCH A;  1L8K A;  2CMA A;  4GE2 A;  2B07 A;  1EEO A;  2BGE A;  1PTT A;  1ZCK A;  2OOQ A;  1ZC0 A;  2QDC A;  3OLR A;  1P15 A;  2B3O A;  2I3U A;  4RI5 A;  4OHD A;  2OC3 A;  4MBB A;  5BZZ A;  5MMZ B;  5KA9 A;  3QCG A;  2CNF A;  4GE6 A;  4PYH A;  1OHE A;  1PA9 A;  4RH5 A;  1XBO A;  1C83 A;  2CNH A;  3BRH A;  2OZ5 A;  2QBS A;  2Q05 A;  3D9C A;  4RI4 A;  5I6V A;  4AZ1 A;  3EAX A;  2QBP A;  2IMG A;  1LYV A;  5GTJ A;  2QBR A;  1PH0 A;  5KAD A;  1BZJ A;  2CM7 A;  3RZ2 A;  3GXH A;  1OET A;  1YTS A;  1C86 A;  2I4H A;  4NYH A;  1R6H A;  1WRM A;  3ZM1 A;  1MKP A;  4HJQ A;  3EB1 A;  1C84 A;  3SR9 A;  2SHP A;  1G1H A;  3V0F A;  2I5X A;  1YFO A;  2F70 A;  3AWE A;  3LJ8 A;  3O4S A;  4NND A;  4KYQ A;  3S4O A;  5KAB A;  2JJD A;  3N0A A;  2B49 A;  2F71 A;  2NV5 A;  4KI9 A;  4OHL A;  1ZZW A;  1YGU A;  2CM2 A;  3A5K A;  1XRI A;  3D1Q A;  4JMK A;  3QCC A;  3QCK A;  2F6T A;  1D5R A;  2QDP A;  4D3Q A;  4D3P A;  2A3K A;  2I75 A;  3I80 A;  3B7O A;  2HB1 A;  1V3A A;  2E0T A;  1NWE A;  3QKP A;  1I9S A;  1EEN A;  1JF7 A;  5KA8 A;  3EMU A;  1I9T A;  1Q6P A;  4H34 A;  2H4V A;  2HY3 A;  3I36 A;  1NNY A;  1PA1 A;  2VEV A;  2F6W A;  3F81 A;  2I3R A;  3ZMP A;  2PT0 A;  2CJZ A;  2HCM A;  1PYN A;  5BX1 A;  4GFV A;  4NWF A;  1NWL A;  2F6Z A;  1PXH A;  3S3H A;  3QCB A;  5M43 A;  4PVG A;  2I6J A;  3AWG A;  2PA5 A;  1G1F A;  3H2X A;  5K9W A;  4I8N A;  3QCD A;  4JNB A;  1YZ4 A;  4GRZ A;  1C87 A;  1YGR A;  2PBN A;  5KA1 A;  1I57 A;  3U96 A;  3S3F A;  3AWF A;  2B4P A;  1C85 A;  1JLN A;  1FQ1 A;  2HNP A;  2BGD A;  3GXG A;  2NT7 A;  4KYR A;  3QCN A;  5EHP A;  1GWZ A;  2FJM A;  3V0E A;  2CM3 A;  1YTW A;  2Y96 A;  3D44 A;  3S4E A;  4YAA A;  1T49 A;  3D1O A;  2I4E A;  3O3L A;  2H4G A;  3ZMQ A;  5K23 A;  2HXP A;  3V0J A;  2M3V A;  2F6F A;  2NLK A;  2Q47 A;  1Q6N A;  5KA7 A;  1KAV A;  1U25 A;  1ONZ A;  4OHI A;  3V0D A;  1YWF A;  1ECV A;  3QCM A;  2RF6 A;  1NZ7 A;  1ZCL A;  2NZ6 A;  3CWE A;  1QXK A;  3EZZ A;  2B4S A;  2C7S A;  2F6Y A;  1OES A;  2H02 A;  5KA3 A;  2I6M A;  2F6V A;  4BJO A;  2AHS A;  2YDU A;  2B4O A;  2PSZ A;  4WTY A;  2GJT A;  2BZL A;  2CMC A;  4J51 A;  3QCI A;  2QDM A;  4QUM A;  3ZV2 A;  2H04 A;  3O4U A;  2HNQ A;  2R0B A;  2QBQ A;  3O4T A;  1Q6T A;  2FJN A;  3F99 A;  4ZN5 A;  4S0G A;  5HDE A;  1OHC A;  1PTU A;  5K22 A;  2ESB A;  2BIJ A;  2F46 A;  2NTA A;  4TVV A;  1OEO X;  2VEY A;  4BPC A;  2PQ5 A;  1RXD A;  2CNG A;  3SME A;  5IBM A;  1M3G A;  2MBC A;  3BLU A;  4DGX A;  3CM3 A;  5K24 A;  2CFV A;  1X24 A;  1YTN A;  3RGQ A;  1FPR A;  3O5X A;  1Q6J A;  2VEW A;  1VHR A;  1LQF A;  1XXP A;  1XXV A;  2H4K A;  4OHH A;  2H03 A;  1AAX A;  2HC2 A;  2Y2F A;  4QUN A;  3BM8 A;  2I6O A;  2ZN7 A;  1L8G A;  4ICZ A;  3QCF A;  2QEP A;  1FPZ A;  4RH9 A;  1OEM X;  2I42 A;  1BZC A;  4RKK A;  4ZI4 A;  1T4J A;  2J16 B;  1WAX A;  4NX8 A;  2AZR A;  1ONY A;  4RHG A;  3V0G A;  4RDD A;  3QCJ A;  3MOZ A;  2WGP A;  3OMH A;  5KA4 A;  2HVL A;  4WOH A;  2OUD A;  4QBE A;  4HRF A;  1PTV A;  4QBW A;  1GFY A;  1U26 A; 
#chains in the Genus database with same CATH topology
 5EHR A;  1G7F A;  1Q6M A;  1LAR A;  3ZM0 A;  2P4D A;  1J4X A;  2QCJ A;  3V0H A;  1G4W R;  3V0I A;  3QCH A;  4OHE A;  1KAK A;  4DGP A;  5BUG A;  3ZM3 A;  4ZIY A;  1RPM A;  2DXP A;  2G6Z A;  3EU0 A;  3F9A A;  1P31 A;  2GWO A;  3RO1 A;  5KA0 A;  3M4U A;  4IKC A;  4Y14 A;  5IBS A;  1PTY A;  3F41 A;  1OEU A;  1OHD A;  2C46 A;  2I1Y A;  3D42 A;  1NL9 A;  4D3R A;  5BZX A;  2X5O A;  2P6X A;  2ZMM A;  2G59 A;  2I4G A;  1Q1M A;  3F9B A;  3S3K A;  1G4U S;  3QKQ A;  2CMB A;  1XM2 A;  4GS0 A;  2JFF A;  1NO6 A;  2BV5 A;  4GFU A;  3QCE A;  3ZM6 A;  4R30 A;  3QCL A;  3MMJ A;  5KAA A;  2JFG A;  5LXQ B;  5KAC A;  4H1O A;  2VEU A;  2A8B A;  4B04 A;  5KA2 A;  2VEX A;  4ZRT A;  5K9V A;  4HJP A;  4ERC A;  4GRY A;  3A5J A;  4Y2E A;  2GP0 A;  2I6P A;  2NT2 A;  1G1G A;  1YN9 A;  1OEV A;  4Z6B A;  1FGS A;  1T48 A;  4JMJ A;  2J17 A;  1GQQ A;  2J16 A;  4GE5 A;  1J6U A;  2CNE A;  4C13 A;  3RGO A;  1E0D A;  2CNI A;  4BUC A;  3I7Z A;  3ZM2 A;  1C88 A;  2CM8 A;  1G7G A;  2B4U A;  2QCT A;  2FH7 A;  1A5Y A;  4R0T A;  5K25 A;  4GWF A;  4WU3 A;  3S3E A;  3D1H A;  3BLT A;  2HC1 A;  3PS5 A;  3N2A A;  1U24 A;  4NWG A;  2UUO A;  1BZH A;  4QAP A;  1Q6S A;  3NME A;  4WU2 A;  2PI7 A;  5AWX A;  4YR8 B;  1SUG A;  1QZ0 A;  4QAH A;  4JBC A;  1YPT A;  2I6I A;  4R0S A;  5J8R A;  3MOW A;  1WCH A;  1L8K A;  2CMA A;  4GE2 A;  2B07 A;  1EEO A;  2BGE A;  1PTT A;  2Y66 A;  1ZCK A;  2OOQ A;  1ZC0 A;  2QDC A;  3OLR A;  3UAG A;  1P15 A;  2B3O A;  2I3U A;  4RI5 A;  4OHD A;  2OC3 A;  4MBB A;  5BZZ A;  1JBV A;  1W7K A;  5MMZ B;  4CVL A;  5KA9 A;  4CVK A;  3QCG A;  2CNF A;  4GE6 A;  4PYH A;  1OHE A;  2JFH A;  1PA9 A;  1EEH A;  4RH5 A;  1XBO A;  1C83 A;  2CNH A;  3BRH A;  2OZ5 A;  2QBS A;  2Q05 A;  3D9C A;  4RI4 A;  5I6V A;  4AZ1 A;  3EAX A;  2QBP A;  2IMG A;  1LYV A;  5GTJ A;  2QBR A;  1PH0 A;  4CVM A;  5KAD A;  1BZJ A;  2CM7 A;  3RZ2 A;  3GXH A;  1OET A;  1E8C A;  1YTS A;  1C86 A;  2I4H A;  4NYH A;  2WTZ A;  3ZM5 A;  1R6H A;  1WRM A;  3ZL8 A;  3ZM1 A;  1MKP A;  4HJQ A;  3EB1 A;  5A5E A;  2Y68 A;  1C84 A;  2Y1O A;  3SR9 A;  2SHP A;  1G1H A;  3V0F A;  2I5X A;  1YFO A;  2F70 A;  3AWE A;  3LJ8 A;  3O4S A;  4NND A;  2VTD A;  4KYQ A;  3S4O A;  5KAB A;  2JJD A;  3N0A A;  2B49 A;  2F71 A;  2NV5 A;  4C12 A;  4KI9 A;  4OHL A;  1ZZW A;  1JBW A;  1YGU A;  2CM2 A;  3A5K A;  1XRI A;  3D1Q A;  4JMK A;  3QCC A;  1UAG A;  3QCK A;  2F6T A;  1D5R A;  2QDP A;  4D3Q A;  4D3P A;  2A3K A;  2I75 A;  3I80 A;  3B7O A;  2HB1 A;  1V3A A;  2E0T A;  1NWE A;  3QKP A;  1I9S A;  1EEN A;  1JF7 A;  5KA8 A;  3EMU A;  1I9T A;  1Q6P A;  4H34 A;  2H4V A;  2HY3 A;  3I36 A;  1NNY A;  1PA1 A;  2VEV A;  2F6W A;  2VTE A;  3F81 A;  2I3R A;  3ZMP A;  4BUB A;  2PT0 A;  2CJZ A;  2HCM A;  1PYN A;  5BX1 A;  3PYZ A;  4GFV A;  4NWF A;  1NWL A;  2F6Z A;  1PXH A;  3S3H A;  3QCB A;  5M43 A;  4PVG A;  1O5Z A;  2I6J A;  1P3D A;  3AWG A;  2PA5 A;  1G1F A;  3H2X A;  5K9W A;  4I8N A;  3QCD A;  4JNB A;  4QF5 A;  1YZ4 A;  4GRZ A;  1C87 A;  1YGR A;  2PBN A;  5KA1 A;  1I57 A;  3U96 A;  2XPC A;  3S3F A;  3AWF A;  2B4P A;  1C85 A;  1JLN A;  1FQ1 A;  2HNP A;  2BGD A;  3GXG A;  2NT7 A;  4KYR A;  3QCN A;  5EHP A;  1GWZ A;  2FJM A;  3V0E A;  2GCA A;  2CM3 A;  2Y67 A;  1YTW A;  1W78 A;  2Y96 A;  3D44 A;  3S4E A;  4YAA A;  1T49 A;  3D1O A;  2I4E A;  3O3L A;  2H4G A;  2GC5 A;  3ZMQ A;  5K23 A;  2VOR A;  2HXP A;  3V0J A;  2GCB A;  2M3V A;  2F00 A;  2F6F A;  2NLK A;  2Q47 A;  1Q6N A;  5KA7 A;  2AM2 A;  1KAV A;  1U25 A;  1ONZ A;  4OHI A;  3V0D A;  2XJA A;  1YWF A;  1ECV A;  3QCM A;  2RF6 A;  2UAG A;  1NZ7 A;  1ZCL A;  2NZ6 A;  3CWE A;  1QXK A;  3EZZ A;  2B4S A;  1GG4 A;  2C7S A;  2F6Y A;  1OES A;  2H02 A;  5KA3 A;  2I6M A;  2F6V A;  4BJO A;  3QCZ A;  2AHS A;  3HN7 A;  2YDU A;  2UUP A;  2B4O A;  2PSZ A;  4WTY A;  2GJT A;  2BZL A;  2CMC A;  4J51 A;  3QCI A;  2QDM A;  4QUM A;  3ZV2 A;  2H04 A;  3O4U A;  2HNQ A;  2R0B A;  2QBQ A;  3O4T A;  1Q6T A;  2FJN A;  3F99 A;  4ZN5 A;  4S0G A;  5HDE A;  1OHC A;  1PTU A;  5K22 A;  2ESB A;  2BIJ A;  2F46 A;  2NTA A;  4TVV A;  3NRS A;  1OEO X;  2VEY A;  2GC6 A;  4BPC A;  2PQ5 A;  1RXD A;  2CNG A;  3SME A;  5IBM A;  1M3G A;  2MBC A;  3BLU A;  4DGX A;  3CM3 A;  5K24 A;  2CFV A;  1X24 A;  1YTN A;  3RGQ A;  1FPR A;  3O5X A;  1Q6J A;  2VEW A;  1VHR A;  1LQF A;  1XXP A;  1XXV A;  2H4K A;  2VOS A;  4OHH A;  2H03 A;  1AAX A;  2HC2 A;  2Y2F A;  4QUN A;  4HV4 A;  3BM8 A;  3LK7 A;  2I6O A;  2ZN7 A;  1L8G A;  4ICZ A;  3QCF A;  2WJP A;  2QEP A;  1FPZ A;  4RH9 A;  1OEM X;  2I42 A;  5A5F A;  1BZC A;  4UAG A;  4RKK A;  4QDI A;  4ZI4 A;  1T4J A;  2J16 B;  1WAX A;  4NX8 A;  1GQY A;  2AZR A;  1ONY A;  4RHG A;  3V0G A;  4RDD A;  3QCJ A;  3MOZ A;  2WGP A;  3OMH A;  5KA4 A;  2HVL A;  4WOH A;  3MVN A;  2OUD A;  4QBE A;  4HRF A;  2AM1 A;  1PTV A;  4QBW A;  1GFY A;  1U26 A; 
#chains in the Genus database with same CATH homology
 5EHR A;  1G7F A;  1Q6M A;  1LAR A;  3ZM0 A;  2P4D A;  1J4X A;  2QCJ A;  3V0H A;  1G4W R;  3V0I A;  3QCH A;  4OHE A;  1KAK A;  4DGP A;  5BUG A;  3ZM3 A;  1RPM A;  2DXP A;  2G6Z A;  3EU0 A;  3F9A A;  2GWO A;  3RO1 A;  5KA0 A;  3M4U A;  4IKC A;  4Y14 A;  5IBS A;  1PTY A;  3F41 A;  1OEU A;  1OHD A;  2C46 A;  2I1Y A;  3D42 A;  1NL9 A;  4D3R A;  5BZX A;  2P6X A;  2ZMM A;  2G59 A;  2I4G A;  1Q1M A;  3F9B A;  3S3K A;  1G4U S;  3QKQ A;  2CMB A;  1XM2 A;  4GS0 A;  1NO6 A;  2BV5 A;  4GFU A;  3QCE A;  4R30 A;  3QCL A;  3MMJ A;  5KAA A;  5LXQ B;  5KAC A;  4H1O A;  2VEU A;  2A8B A;  4B04 A;  5KA2 A;  2VEX A;  4ZRT A;  5K9V A;  4HJP A;  4ERC A;  4GRY A;  3A5J A;  4Y2E A;  2GP0 A;  2I6P A;  2NT2 A;  1G1G A;  1YN9 A;  1OEV A;  4Z6B A;  1T48 A;  4JMJ A;  2J17 A;  2J16 A;  4GE5 A;  2CNE A;  3RGO A;  2CNI A;  3I7Z A;  3ZM2 A;  1C88 A;  2CM8 A;  1G7G A;  2B4U A;  2QCT A;  2FH7 A;  1A5Y A;  4R0T A;  5K25 A;  4GWF A;  4WU3 A;  3S3E A;  3D1H A;  3BLT A;  2HC1 A;  3PS5 A;  1U24 A;  4NWG A;  1BZH A;  4QAP A;  1Q6S A;  3NME A;  4WU2 A;  2PI7 A;  5AWX A;  4YR8 B;  1SUG A;  1QZ0 A;  4QAH A;  4JBC A;  1YPT A;  2I6I A;  4R0S A;  5J8R A;  3MOW A;  1WCH A;  1L8K A;  2CMA A;  4GE2 A;  2B07 A;  1EEO A;  2BGE A;  1PTT A;  1ZCK A;  2OOQ A;  1ZC0 A;  2QDC A;  3OLR A;  1P15 A;  2B3O A;  2I3U A;  4RI5 A;  4OHD A;  2OC3 A;  4MBB A;  5BZZ A;  5MMZ B;  5KA9 A;  3QCG A;  2CNF A;  4GE6 A;  4PYH A;  1OHE A;  1PA9 A;  4RH5 A;  1XBO A;  1C83 A;  2CNH A;  3BRH A;  2OZ5 A;  2QBS A;  2Q05 A;  3D9C A;  4RI4 A;  5I6V A;  4AZ1 A;  3EAX A;  2QBP A;  2IMG A;  1LYV A;  5GTJ A;  2QBR A;  1PH0 A;  5KAD A;  1BZJ A;  2CM7 A;  3RZ2 A;  3GXH A;  1OET A;  1YTS A;  1C86 A;  2I4H A;  4NYH A;  1R6H A;  1WRM A;  3ZM1 A;  1MKP A;  4HJQ A;  3EB1 A;  1C84 A;  3SR9 A;  2SHP A;  1G1H A;  3V0F A;  2I5X A;  1YFO A;  2F70 A;  3AWE A;  3LJ8 A;  3O4S A;  4NND A;  4KYQ A;  3S4O A;  5KAB A;  2JJD A;  3N0A A;  2B49 A;  2F71 A;  2NV5 A;  4KI9 A;  4OHL A;  1ZZW A;  1YGU A;  2CM2 A;  3A5K A;  1XRI A;  3D1Q A;  4JMK A;  3QCC A;  3QCK A;  2F6T A;  1D5R A;  2QDP A;  4D3Q A;  4D3P A;  2A3K A;  2I75 A;  3I80 A;  3B7O A;  2HB1 A;  1V3A A;  2E0T A;  1NWE A;  3QKP A;  1I9S A;  1EEN A;  1JF7 A;  5KA8 A;  3EMU A;  1I9T A;  1Q6P A;  4H34 A;  2H4V A;  2HY3 A;  3I36 A;  1NNY A;  1PA1 A;  2VEV A;  2F6W A;  3F81 A;  2I3R A;  3ZMP A;  2PT0 A;  2CJZ A;  2HCM A;  1PYN A;  5BX1 A;  4GFV A;  4NWF A;  1NWL A;  2F6Z A;  1PXH A;  3S3H A;  3QCB A;  5M43 A;  4PVG A;  2I6J A;  3AWG A;  2PA5 A;  1G1F A;  3H2X A;  5K9W A;  4I8N A;  3QCD A;  4JNB A;  1YZ4 A;  4GRZ A;  1C87 A;  1YGR A;  2PBN A;  5KA1 A;  1I57 A;  3U96 A;  3S3F A;  3AWF A;  2B4P A;  1C85 A;  1JLN A;  1FQ1 A;  2HNP A;  2BGD A;  3GXG A;  2NT7 A;  4KYR A;  3QCN A;  5EHP A;  1GWZ A;  2FJM A;  3V0E A;  2CM3 A;  1YTW A;  2Y96 A;  3D44 A;  3S4E A;  4YAA A;  1T49 A;  3D1O A;  2I4E A;  3O3L A;  2H4G A;  3ZMQ A;  5K23 A;  2HXP A;  3V0J A;  2M3V A;  2F6F A;  2NLK A;  2Q47 A;  1Q6N A;  5KA7 A;  1KAV A;  1U25 A;  1ONZ A;  4OHI A;  3V0D A;  1YWF A;  1ECV A;  3QCM A;  2RF6 A;  1NZ7 A;  1ZCL A;  2NZ6 A;  3CWE A;  1QXK A;  3EZZ A;  2B4S A;  2C7S A;  2F6Y A;  1OES A;  2H02 A;  5KA3 A;  2I6M A;  2F6V A;  4BJO A;  2AHS A;  2YDU A;  2B4O A;  2PSZ A;  4WTY A;  2GJT A;  2BZL A;  2CMC A;  4J51 A;  3QCI A;  2QDM A;  4QUM A;  3ZV2 A;  2H04 A;  3O4U A;  2HNQ A;  2R0B A;  2QBQ A;  3O4T A;  1Q6T A;  2FJN A;  3F99 A;  4ZN5 A;  4S0G A;  5HDE A;  1OHC A;  1PTU A;  5K22 A;  2ESB A;  2BIJ A;  2F46 A;  2NTA A;  4TVV A;  1OEO X;  2VEY A;  4BPC A;  2PQ5 A;  1RXD A;  2CNG A;  3SME A;  5IBM A;  1M3G A;  2MBC A;  3BLU A;  4DGX A;  3CM3 A;  5K24 A;  2CFV A;  1X24 A;  1YTN A;  3RGQ A;  1FPR A;  3O5X A;  1Q6J A;  2VEW A;  1VHR A;  1LQF A;  1XXP A;  1XXV A;  2H4K A;  4OHH A;  2H03 A;  1AAX A;  2HC2 A;  2Y2F A;  4QUN A;  3BM8 A;  2I6O A;  2ZN7 A;  1L8G A;  4ICZ A;  3QCF A;  2QEP A;  1FPZ A;  4RH9 A;  1OEM X;  2I42 A;  1BZC A;  4RKK A;  4ZI4 A;  1T4J A;  2J16 B;  1WAX A;  4NX8 A;  2AZR A;  1ONY A;  4RHG A;  3V0G A;  4RDD A;  3QCJ A;  3MOZ A;  2WGP A;  3OMH A;  5KA4 A;  2HVL A;  4WOH A;  2OUD A;  4QBE A;  4HRF A;  1PTV A;  4QBW A;  1GFY A;  1U26 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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