1PLOA

Transforming growth factor-beta type ii receptor extracellular domain
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
122
structure length
122
Chain Sequence
VTDNAGAVKFPQLCKFCDVRFSTCDNQKSCMSNCSITSICEKPQEVCVAVWRKNDENITLETVCHDPKLPYHDFILEDAASPKCIMKEKKKPGETFFMCSCSSDECNDNIIFSEEYNTSNPD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure and backbone dynamics of the TGF-beta type II receptor extracellular domain
pubmed doi rcsb
molecule keywords TGF-beta receptor type II
molecule tags Cytokine receptor
source organism Homo sapiens
total genus 10
structure length 122
sequence length 122
ec nomenclature ec 2.7.11.30: Receptor protein serine/threonine kinase.
pdb deposition date 2003-06-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08917 ecTbetaR2 Transforming growth factor beta receptor 2 ectodomain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.60.10 Mainly Beta Ribbon CD59 CD59 1ploA00
1KC4A 1UG4A 2UX2A 1JGKA 1FFJA 1CTXA 3LAQU 1KBTA 3U74U 1JE9A 1HC9B 1RL5A 1IDLA 2GOOC 4OM5A 1FF4A 1M9ZA 2PJYB 1G6MA 2N99A 2MJ4A 2H5FA 3VTSA 2H7ZA 2H8UA 5DU1A 1HOYA 1BXPA 1CDQA 2BHIA 2H64C 2ABXA 1KTZB 1TGXA 1CDRA 1IKCA 2QJBC 1MAHF 1HC9A 1KBSA 2K3GA 1CB9A 2HLQA 1NXBA 4ZQYA 6EBXA 2MJYA 4UY2C 2BTXA 1F8UB 2MJ0A 4BDTB 3ERAA 2H7ZB 4AEAA 1ABTA 1ES7B 1CCQA 4OM4A 1NTXA 2CTXA 2QJAC 3NEQA 1LX5B 1KS6A 2MUPA 1KXIA 1ONJA 3HH7A 1H0JA 2H62D 1LJZA 1S4YA 2H62C 3PLCA 1DRSA 1CXNA 1LSIA 1IDHA 2JVEA 1CDTA 2CRTA 1CVOA 1IDGA 2L03A 3EVSC 1BTEA 4P7UA 1YWHA 1CDSA 3BT2U 1NORA 1QKEA 1QKDA 1ERGA 4HQPF 5EBXA 1KL8A 2MUOA 2NBTA 1CXOA 2L5SA 1CREA 2CRSA 4QTIU 1NEAA 3U73U 1LXHA 4XJJA 1KFHA 3QB4B 2UWRA 4DO8A 1TXAA 2VLWA 1FASA 1KBAA 1FSSB 1F94A 1NYSA 2GOOB 1FRAA 1QM7A 3FEVA 2QJ9C 2CDXA 1VB0A 1V6PA 2X8BB 1TXBA 2LA1A 1TFSA 1IDIA 2OFSA 1W6BA 2H64B 4IYEA 1ZADA 1COEA 1REWC 1FSCA 1KU6B 2FD6U 1NYUA 1HAJA 1ERAA 1JBDA 1CHVS 3BT1U 2I9BE 2PJYC 3KFDI 1LXGA 1IK8A 1IQ9A 2J8BA 5DO6A 4RUDA 5DZ5A 4BIKB 1PLOA 2ERAA 4LFTA 1CODA 4FAOC 4EY8B 1RGJA 2MHYA 4FAOE 3EBXA 1XT3A 2MFAA 1CRFA 1L4WA 2JQPA 1B41B 3NDSA 5IMYC 2QC1A 3KFDE 2LCRA 1MR6A 5IMTD 1NTNA 3NH7A 1I02A 1IJCA 2CCXA 2HLRA 1HAAA
chains in the Genus database with same CATH superfamily
1KC4A 1UG4A 2UX2A 1JGKA 1FFJA 1CTXA 3LAQU 1KBTA 3U74U 1JE9A 1HC9B 1RL5A 1IDLA 2GOOC 4OM5A 1FF4A 1M9ZA 2PJYB 1G6MA 4KSNA 2N99A 2MJ4A 2H5FA 3VTSA 2H7ZA 2H8UA 5DU1A 1HOYA 1BXPA 1CDQA 2BHIA 2H64C 2ABXA 1KTZB 1TGXA 1CDRA 1IKCA 2QJBC 1MAHF 1HC9A 1KBSA 2K3GA 1CB9A 2HLQA 1NXBA 4ZQYA 6EBXA 2MJYA 4UY2C 2BTXA 1F8UB 2MJ0A 4BDTB 3ERAA 2H7ZB 4AEAA 1ABTA 1ES7B 1CCQA 4OM4A 1NTXA 2CTXA 2QJAC 3NEQA 1LX5B 1KS6A 2MUPA 1KXIA 1ONJA 3HH7A 1H0JA 2H62D 1LJZA 1S4YA 2H62C 3PLCA 1DRSA 1CXNA 1LSIA 1IDHA 2JVEA 1CDTA 2CRTA 1CVOA 1IDGA 2L03A 3EVSC 1BTEA 4P7UA 1YWHA 1CDSA 3BT2U 1NORA 1QKEA 1QKDA 1ERGA 4HQPF 5EBXA 1KL8A 2MUOA 2NBTA 1CXOA 2L5SA 1CREA 2CRSA 4QTIU 1NEAA 3U73U 1LXHA 4XJJA 1KFHA 3QB4B 2UWRA 4DO8A 1TXAA 2VLWA 1FASA 1KBAA 1FSSB 1F94A 1NYSA 2GOOB 1FRAA 1QM7A 3FEVA 2QJ9C 2CDXA 1VB0A 1V6PA 2X8BB 1TXBA 2LA1A 1TFSA 1IDIA 2OFSA 1W6BA 2H64B 4IYEA 1ZADA 1COEA 1REWC 1FSCA 1KU6B 2FD6U 1NYUA 1HAJA 1ERAA 1JBDA 1CHVS 3BT1U 2I9BE 2PJYC 3KFDI 1LXGA 1IK8A 1IQ9A 2J8BA 5DO6A 4RUDA 5DZ5A 4BIKB 1PLOA 2ERAA 4LFTA 1CODA 4FAOC 4EY8B 1RGJA 2MHYA 4FAOE 3EBXA 1XT3A 2MFAA 1CRFA 1L4WA 2JQPA 1B41B 3NDSA 5IMYC 2QC1A 3KFDE 2LCRA 1MR6A 5IMTD 1NTNA 3NH7A 1I02A 1IJCA 2CCXA 2HLRA 1HAAA
chains in the Genus database with same CATH topology
1KC4A 1UG4A 2UX2A 1JGKA 1FFJA 1CTXA 3LAQU 1KBTA 3U74U 1JE9A 1HC9B 1RL5A 1IDLA 2GOOC 4OM5A 1FF4A 1M9ZA 2PJYB 1G6MA 4KSNA 2N99A 2MJ4A 2H5FA 3VTSA 2H7ZA 2H8UA 5DU1A 1HOYA 1BXPA 1CDQA 2BHIA 2H64C 2ABXA 1KTZB 1TGXA 1CDRA 1IKCA 2QJBC 1MAHF 1HC9A 1KBSA 2K3GA 1CB9A 2HLQA 1NXBA 4ZQYA 6EBXA 2MJYA 4UY2C 2BTXA 1F8UB 2MJ0A 4BDTB 3ERAA 2H7ZB 4AEAA 1ABTA 1ES7B 1CCQA 4OM4A 1NTXA 2CTXA 2QJAC 3NEQA 1LX5B 1KS6A 2MUPA 1KXIA 1ONJA 3HH7A 1H0JA 2H62D 1LJZA 1S4YA 2H62C 3PLCA 1DRSA 1CXNA 1LSIA 1IDHA 2JVEA 1CDTA 2CRTA 1CVOA 1IDGA 2L03A 3EVSC 1BTEA 4P7UA 1YWHA 1CDSA 3BT2U 1NORA 1QKEA 1QKDA 1ERGA 4HQPF 5EBXA 1KL8A 2MUOA 2NBTA 1CXOA 2L5SA 1CREA 2CRSA 4QTIU 1NEAA 3U73U 1LXHA 4XJJA 1KFHA 3QB4B 2UWRA 4DO8A 1TXAA 2VLWA 1FASA 1KBAA 1FSSB 1F94A 1NYSA 2GOOB 1FRAA 1QM7A 3FEVA 2QJ9C 2CDXA 1VB0A 1V6PA 2X8BB 1TXBA 2LA1A 1TFSA 1IDIA 2OFSA 1W6BA 2H64B 4IYEA 1ZADA 1COEA 1REWC 1FSCA 1KU6B 2FD6U 1NYUA 1HAJA 1ERAA 1JBDA 1CHVS 3BT1U 2I9BE 2PJYC 3KFDI 1LXGA 1IK8A 1IQ9A 2J8BA 5DO6A 4RUDA 5DZ5A 4BIKB 1PLOA 2ERAA 4LFTA 1CODA 4FAOC 4EY8B 1RGJA 2MHYA 4FAOE 3EBXA 1XT3A 2MFAA 1CRFA 1L4WA 2JQPA 1B41B 3NDSA 5IMYC 2QC1A 3KFDE 2LCRA 1MR6A 5IMTD 1NTNA 3NH7A 1I02A 1IJCA 2CCXA 2HLRA 1HAAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KC4 A;  1UG4 A;  2UX2 A;  1JGK A;  1FFJ A;  1CTX A;  3LAQ U;  1KBT A;  3U74 U;  1JE9 A;  1HC9 B;  1RL5 A;  1IDL A;  2GOO C;  4OM5 A;  1FF4 A;  1M9Z A;  2PJY B;  1G6M A;  2N99 A;  2MJ4 A;  2H5F A;  3VTS A;  2H7Z A;  2H8U A;  5DU1 A;  1HOY A;  1BXP A;  1CDQ A;  2BHI A;  2H64 C;  2ABX A;  1KTZ B;  1TGX A;  1CDR A;  1IKC A;  2QJB C;  1MAH F;  1HC9 A;  1KBS A;  2K3G A;  1CB9 A;  2HLQ A;  1NXB A;  4ZQY A;  6EBX A;  2MJY A;  4UY2 C;  2BTX A;  1F8U B;  2MJ0 A;  4BDT B;  3ERA A;  2H7Z B;  4AEA A;  1ABT A;  1ES7 B;  1CCQ A;  4OM4 A;  1NTX A;  2CTX A;  2QJA C;  3NEQ A;  1LX5 B;  1KS6 A;  2MUP A;  1KXI A;  1ONJ A;  3HH7 A;  1H0J A;  2H62 D;  1LJZ A;  1S4Y A;  2H62 C;  3PLC A;  1DRS A;  1CXN A;  1LSI A;  1IDH A;  2JVE A;  1CDT A;  2CRT A;  1CVO A;  1IDG A;  2L03 A;  3EVS C;  1BTE A;  4P7U A;  1YWH A;  1CDS A;  3BT2 U;  1NOR A;  1QKE A;  1QKD A;  1ERG A;  4HQP F;  5EBX A;  1KL8 A;  2MUO A;  2NBT A;  1CXO A;  2L5S A;  1CRE A;  2CRS A;  4QTI U;  1NEA A;  3U73 U;  1LXH A;  4XJJ A;  1KFH A;  3QB4 B;  2UWR A;  4DO8 A;  1TXA A;  2VLW A;  1FAS A;  1KBA A;  1FSS B;  1F94 A;  1NYS A;  2GOO B;  1FRA A;  1QM7 A;  3FEV A;  2QJ9 C;  2CDX A;  1VB0 A;  1V6P A;  2X8B B;  1TXB A;  2LA1 A;  1TFS A;  1IDI A;  2OFS A;  1W6B A;  2H64 B;  4IYE A;  1ZAD A;  1COE A;  1REW C;  1FSC A;  1KU6 B;  2FD6 U;  1NYU A;  1HAJ A;  1ERA A;  1JBD A;  1CHV S;  3BT1 U;  2I9B E;  2PJY C;  3KFD I;  1LXG A;  1IK8 A;  1IQ9 A;  2J8B A;  5DO6 A;  4RUD A;  5DZ5 A;  4BIK B;  1PLO A;  2ERA A;  4LFT A;  1COD A;  4FAO C;  4EY8 B;  1RGJ A;  2MHY A;  4FAO E;  3EBX A;  1XT3 A;  2MFA A;  1CRF A;  1L4W A;  2JQP A;  1B41 B;  3NDS A;  5IMY C;  2QC1 A;  3KFD E;  2LCR A;  1MR6 A;  5IMT D;  1NTN A;  3NH7 A;  1I02 A;  1IJC A;  2CCX A;  2HLR A;  1HAA A; 
#chains in the Genus database with same CATH topology
 1KC4 A;  1UG4 A;  2UX2 A;  1JGK A;  1FFJ A;  1CTX A;  3LAQ U;  1KBT A;  3U74 U;  1JE9 A;  1HC9 B;  1RL5 A;  1IDL A;  2GOO C;  4OM5 A;  1FF4 A;  1M9Z A;  2PJY B;  1G6M A;  4KSN A;  2N99 A;  2MJ4 A;  2H5F A;  3VTS A;  2H7Z A;  2H8U A;  5DU1 A;  1HOY A;  1BXP A;  1CDQ A;  2BHI A;  2H64 C;  2ABX A;  1KTZ B;  1TGX A;  1CDR A;  1IKC A;  2QJB C;  1MAH F;  1HC9 A;  1KBS A;  2K3G A;  1CB9 A;  2HLQ A;  1NXB A;  4ZQY A;  6EBX A;  2MJY A;  4UY2 C;  2BTX A;  1F8U B;  2MJ0 A;  4BDT B;  3ERA A;  2H7Z B;  4AEA A;  1ABT A;  1ES7 B;  1CCQ A;  4OM4 A;  1NTX A;  2CTX A;  2QJA C;  3NEQ A;  1LX5 B;  1KS6 A;  2MUP A;  1KXI A;  1ONJ A;  3HH7 A;  1H0J A;  2H62 D;  1LJZ A;  1S4Y A;  2H62 C;  3PLC A;  1DRS A;  1CXN A;  1LSI A;  1IDH A;  2JVE A;  1CDT A;  2CRT A;  1CVO A;  1IDG A;  2L03 A;  3EVS C;  1BTE A;  4P7U A;  1YWH A;  1CDS A;  3BT2 U;  1NOR A;  1QKE A;  1QKD A;  1ERG A;  4HQP F;  5EBX A;  1KL8 A;  2MUO A;  2NBT A;  1CXO A;  2L5S A;  1CRE A;  2CRS A;  4QTI U;  1NEA A;  3U73 U;  1LXH A;  4XJJ A;  1KFH A;  3QB4 B;  2UWR A;  4DO8 A;  1TXA A;  2VLW A;  1FAS A;  1KBA A;  1FSS B;  1F94 A;  1NYS A;  2GOO B;  1FRA A;  1QM7 A;  3FEV A;  2QJ9 C;  2CDX A;  1VB0 A;  1V6P A;  2X8B B;  1TXB A;  2LA1 A;  1TFS A;  1IDI A;  2OFS A;  1W6B A;  2H64 B;  4IYE A;  1ZAD A;  1COE A;  1REW C;  1FSC A;  1KU6 B;  2FD6 U;  1NYU A;  1HAJ A;  1ERA A;  1JBD A;  1CHV S;  3BT1 U;  2I9B E;  2PJY C;  3KFD I;  1LXG A;  1IK8 A;  1IQ9 A;  2J8B A;  5DO6 A;  4RUD A;  5DZ5 A;  4BIK B;  1PLO A;  2ERA A;  4LFT A;  1COD A;  4FAO C;  4EY8 B;  1RGJ A;  2MHY A;  4FAO E;  3EBX A;  1XT3 A;  2MFA A;  1CRF A;  1L4W A;  2JQP A;  1B41 B;  3NDS A;  5IMY C;  2QC1 A;  3KFD E;  2LCR A;  1MR6 A;  5IMT D;  1NTN A;  3NH7 A;  1I02 A;  1IJC A;  2CCX A;  2HLR A;  1HAA A; 
#chains in the Genus database with same CATH homology
 1KC4 A;  1UG4 A;  2UX2 A;  1JGK A;  1FFJ A;  1CTX A;  3LAQ U;  1KBT A;  3U74 U;  1JE9 A;  1HC9 B;  1RL5 A;  1IDL A;  2GOO C;  4OM5 A;  1FF4 A;  1M9Z A;  2PJY B;  1G6M A;  4KSN A;  2N99 A;  2MJ4 A;  2H5F A;  3VTS A;  2H7Z A;  2H8U A;  5DU1 A;  1HOY A;  1BXP A;  1CDQ A;  2BHI A;  2H64 C;  2ABX A;  1KTZ B;  1TGX A;  1CDR A;  1IKC A;  2QJB C;  1MAH F;  1HC9 A;  1KBS A;  2K3G A;  1CB9 A;  2HLQ A;  1NXB A;  4ZQY A;  6EBX A;  2MJY A;  4UY2 C;  2BTX A;  1F8U B;  2MJ0 A;  4BDT B;  3ERA A;  2H7Z B;  4AEA A;  1ABT A;  1ES7 B;  1CCQ A;  4OM4 A;  1NTX A;  2CTX A;  2QJA C;  3NEQ A;  1LX5 B;  1KS6 A;  2MUP A;  1KXI A;  1ONJ A;  3HH7 A;  1H0J A;  2H62 D;  1LJZ A;  1S4Y A;  2H62 C;  3PLC A;  1DRS A;  1CXN A;  1LSI A;  1IDH A;  2JVE A;  1CDT A;  2CRT A;  1CVO A;  1IDG A;  2L03 A;  3EVS C;  1BTE A;  4P7U A;  1YWH A;  1CDS A;  3BT2 U;  1NOR A;  1QKE A;  1QKD A;  1ERG A;  4HQP F;  5EBX A;  1KL8 A;  2MUO A;  2NBT A;  1CXO A;  2L5S A;  1CRE A;  2CRS A;  4QTI U;  1NEA A;  3U73 U;  1LXH A;  4XJJ A;  1KFH A;  3QB4 B;  2UWR A;  4DO8 A;  1TXA A;  2VLW A;  1FAS A;  1KBA A;  1FSS B;  1F94 A;  1NYS A;  2GOO B;  1FRA A;  1QM7 A;  3FEV A;  2QJ9 C;  2CDX A;  1VB0 A;  1V6P A;  2X8B B;  1TXB A;  2LA1 A;  1TFS A;  1IDI A;  2OFS A;  1W6B A;  2H64 B;  4IYE A;  1ZAD A;  1COE A;  1REW C;  1FSC A;  1KU6 B;  2FD6 U;  1NYU A;  1HAJ A;  1ERA A;  1JBD A;  1CHV S;  3BT1 U;  2I9B E;  2PJY C;  3KFD I;  1LXG A;  1IK8 A;  1IQ9 A;  2J8B A;  5DO6 A;  4RUD A;  5DZ5 A;  4BIK B;  1PLO A;  2ERA A;  4LFT A;  1COD A;  4FAO C;  4EY8 B;  1RGJ A;  2MHY A;  4FAO E;  3EBX A;  1XT3 A;  2MFA A;  1CRF A;  1L4W A;  2JQP A;  1B41 B;  3NDS A;  5IMY C;  2QC1 A;  3KFD E;  2LCR A;  1MR6 A;  5IMT D;  1NTN A;  3NH7 A;  1I02 A;  1IJC A;  2CCX A;  2HLR A;  1HAA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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