1PMXA

Insulin-like growth factor-i bound to a phage-derived peptide
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
70
structure length
70
Chain Sequence
GPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hormone/growth factor
molecule keywords Insulin-like growth factor IB
publication title Complex with a Phage Display-Derived Peptide Provides Insight into the Function of Insulin-like Growth Factor I
pubmed doi rcsb
source organism Homo sapiens
total genus 10
structure length 70
sequence length 70
ec nomenclature
pdb deposition date 2003-06-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00049 Insulin Insulin/IGF/Relaxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.10 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like 1pmxA00
1ZEIA 5L3NA 1H59A 2LWZA 2L29B 3KR3D 1B9GA 3LRIA 1BQTA 1H02B 1GZYB 2DSRI 1WQJI 2DSPI 1GZZB 1IGLA 1IMXA 5L3LA 2DSQC 5L3MA 2KJIA 1SJUA 1PMXA 1TGRA 2GF1A 2KQPA 1GZRB 1EFEA 3GF1A 2JZQA 4XSSB 6INSE
chains in the Genus database with same CATH superfamily
1ZEIA 5L3NA 1H59A 2LWZA 2L29B 3KR3D 1B9GA 3LRIA 3F2CA 1BQTA 1H02B 1GZYB 2DSRI 3F2BA 1WQJI 2DSPI 1GZZB 1IGLA 1IMXA 5L3LA 2L14B 2DSQC 5L3MA 2KJIA 1SJUA 1PMXA 1TGRA 2GF1A 2KQPA 1GZRB 1EFEA 3GF1A 2JZQA 4XSSB 6INSE 3F2DA
chains in the Genus database with same CATH topology
1ZEIA 5L3NA 1H59A 2LWZA 2L29B 3KR3D 1B9GA 3LRIA 1BQTA 1H02B 1GZYB 2DSRI 1WQJI 2DSPI 1GZZB 1IGLA 1IMXA 5L3LA 2DSQC 5L3MA 2KJIA 1SJUA 1PMXA 1TGRA 2GF1A 2KQPA 1GZRB 1EFEA 3GF1A 2JZQA 4XSSB 6INSE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ZEI A;  5L3N A;  1H59 A;  2LWZ A;  2L29 B;  3KR3 D;  1B9G A;  3LRI A;  1BQT A;  1H02 B;  1GZY B;  2DSR I;  1WQJ I;  2DSP I;  1GZZ B;  1IGL A;  1IMX A;  5L3L A;  2DSQ C;  5L3M A;  2KJI A;  1SJU A;  1PMX A;  1TGR A;  2GF1 A;  2KQP A;  1GZR B;  1EFE A;  3GF1 A;  2JZQ A;  4XSS B;  6INS E; 
#chains in the Genus database with same CATH topology
 1ZEI A;  5L3N A;  1H59 A;  2LWZ A;  2L29 B;  3KR3 D;  1B9G A;  3LRI A;  3F2C A;  1BQT A;  1H02 B;  1GZY B;  2DSR I;  3F2B A;  1WQJ I;  2DSP I;  1GZZ B;  1IGL A;  1IMX A;  5L3L A;  2L14 B;  2DSQ C;  5L3M A;  2KJI A;  1SJU A;  1PMX A;  1TGR A;  2GF1 A;  2KQP A;  1GZR B;  1EFE A;  3GF1 A;  2JZQ A;  4XSS B;  6INS E;  3F2D A; 
#chains in the Genus database with same CATH homology
 1ZEI A;  5L3N A;  1H59 A;  2LWZ A;  2L29 B;  3KR3 D;  1B9G A;  3LRI A;  1BQT A;  1H02 B;  1GZY B;  2DSR I;  1WQJ I;  2DSP I;  1GZZ B;  1IGL A;  1IMX A;  5L3L A;  2DSQ C;  5L3M A;  2KJI A;  1SJU A;  1PMX A;  1TGR A;  2GF1 A;  2KQP A;  1GZR B;  1EFE A;  3GF1 A;  2JZQ A;  4XSS B;  6INS E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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