1PN5A

Nmr structure of the nalp1 pyrin domain (pyd)
Total Genus 23
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
93
structure length
93
Chain Sequence
MAGGAWGRLACYLEFLKKEELKEFQLLLANKAHSRSSSGETPAQPEKTSGMEVASYLVAQYGEQRAWDLALHTWEQMGLRSLCAQAQEGAGHS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title NMR structure of the apoptosis- and inflammation-related NALP1 pyrin domain
pubmed doi rcsb
molecule tags Apoptosis
source organism Homo sapiens
molecule keywords NACHT-, LRR- and PYD-containing protein 2
total genus 23
structure length 93
sequence length 93
ec nomenclature
pdb deposition date 2003-06-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01378 IgG_binding_B B domain
A PF02758 PYRIN PAAD/DAPIN/Pyrin domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 1pn5A00
1E3YA 4D8OA 1A1ZA 1DGNA 2L6AA 1E41A 2N83A 1ICHA 1CWWA 2YGSA 2F1SA 2A9IA 4FH0A 4O9FA 2MB9A 2N97A 2BBRA 1D2ZA 2OF5H 3T6PA 2DBDA 4M9SA 3EZQA 4DWNA 2MS8A 4M9ZA 4EWIA 2DBHA 2LWEA 4LWDA 4A2QA 2MN4A 2O71A 4N1KA 2VGQA 3CRDA 4I16A 3KATA 3YGSP 2YQFA 2KN6A 2YVIA 2G7RA 4P4HA 1D2ZB 2NSNA 2A5YB 4A2WA 3EZQB 3J6JA 4ZBWA 2DBGA 4O7QA 4IZ7B 2B1WA 3LQQA 3YGSC 4JQWA 2LWDA 4JUPA 4N1LA 2IB1A 1WH4A 2MPCA 2N7ZA 4IZ5E 4N1JA 1C15A 1PN5A 2YU0A 3LQRA 4RHWA 2N1FA 4O9LA 4UZ0A 2LS7A 3MOPG 4F44A 4P4HI 1N3KA 2N80A 4QOBA 1DDFA 1WMGA 4M9XA 2L9MA 2DBFA 2GF5A 1Z6TA 2HM2Q 3CL3A 1UCPA 3MOPK 4E9MA 4F42A 3J63A 1WXPA 2BBZA 2DO9A 1CY5A 3QF2A 2KM6A 3MOPA 2P1HA 1YGOA 1NGRA 2MS7A 1A1WA 2D96A 2N00A 1FADA 4NQKA 2NZ7A 2NAQA 4IZAB 4RHWE 2M5VA 2OF5A 4O6XA
chains in the Genus database with same CATH superfamily
1E3YA 4D8OA 1A1ZA 1DGNA 2L6AA 1E41A 2N83A 1ICHA 1CWWA 2YGSA 2F1SA 2A9IA 4FH0A 4O9FA 2MB9A 2N97A 2BBRA 1D2ZA 2OF5H 3T6PA 2DBDA 4M9SA 2MJMA 3EZQA 4DWNA 2MS8A 4M9ZA 4EWIA 2DBHA 2LWEA 4LWDA 4A2QA 2MN4A 2O71A 4N1KA 2VGQA 3CRDA 4I16A 3KATA 3YGSP 2YQFA 2KN6A 2YVIA 2G7RA 4P4HA 1D2ZB 2NSNA 2A5YB 4A2WA 3EZQB 3J6JA 4ZBWA 2DBGA 4O7QA 4IZ7B 2B1WA 3LQQA 3YGSC 4JQWA 2LWDA 4JUPA 4N1LA 2IB1A 1WH4A 2MPCA 2N7ZA 4IZ5E 4N1JA 1C15A 1PN5A 2YU0A 3LQRA 4RHWA 2N1FA 4O9LA 4UZ0A 2LS7A 3MOPG 4F44A 4P4HI 1N3KA 2N80A 4QOBA 1DDFA 1WMGA 4M9XA 2L9MA 2DBFA 2GF5A 1Z6TA 2HM2Q 3CL3A 1UCPA 3MOPK 4E9MA 4F42A 3J63A 1WXPA 2BBZA 2DO9A 1CY5A 3QF2A 2KM6A 3MOPA 2P1HA 1YGOA 1NGRA 2MS7A 1A1WA 2D96A 2N00A 1FADA 2XV9A 4NQKA 2NZ7A 2NAQA 4IZAB 4RHWE 2M5VA 2OF5A 4O6XA
chains in the Genus database with same CATH topology
1E3YA 4D8OA 1A1ZA 1DGNA 2L6AA 1E41A 2N83A 1ICHA 1CWWA 2YGSA 2F1SA 2A9IA 4FH0A 4O9FA 2MB9A 2N97A 2BBRA 1D2ZA 2OF5H 3T6PA 2DBDA 4M9SA 2MJMA 3EZQA 4DWNA 2MS8A 4M9ZA 4EWIA 2DBHA 2LWEA 4LWDA 4A2QA 2MN4A 2O71A 4N1KA 2VGQA 3CRDA 4I16A 3KATA 3YGSP 2YQFA 2KN6A 2YVIA 2G7RA 4P4HA 1D2ZB 2NSNA 2A5YB 4A2WA 3EZQB 3J6JA 4ZBWA 2DBGA 4O7QA 4IZ7B 2B1WA 3LQQA 3YGSC 4JQWA 2LWDA 4JUPA 4N1LA 2IB1A 1WH4A 2MPCA 2N7ZA 4IZ5E 4N1JA 1C15A 1PN5A 2YU0A 3LQRA 4RHWA 2N1FA 4O9LA 4UZ0A 2LS7A 3MOPG 4F44A 4P4HI 1N3KA 2N80A 4QOBA 1DDFA 1WMGA 4M9XA 2L9MA 2DBFA 2GF5A 1Z6TA 2HM2Q 3CL3A 1UCPA 3MOPK 4E9MA 4F42A 3J63A 1WXPA 2BBZA 2DO9A 1CY5A 3QF2A 2KM6A 3MOPA 2P1HA 1YGOA 1NGRA 2MS7A 1A1WA 2D96A 2N00A 1FADA 2XV9A 4NQKA 2NZ7A 2NAQA 4IZAB 4RHWE 2M5VA 2OF5A 4O6XA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1E3Y A;  4D8O A;  1A1Z A;  1DGN A;  2L6A A;  1E41 A;  2N83 A;  1ICH A;  1CWW A;  2YGS A;  2F1S A;  2A9I A;  4FH0 A;  4O9F A;  2MB9 A;  2N97 A;  2BBR A;  1D2Z A;  2OF5 H;  3T6P A;  2DBD A;  4M9S A;  3EZQ A;  4DWN A;  2MS8 A;  4M9Z A;  4EWI A;  2DBH A;  2LWE A;  4LWD A;  4A2Q A;  2MN4 A;  2O71 A;  4N1K A;  2VGQ A;  3CRD A;  4I16 A;  3KAT A;  3YGS P;  2YQF A;  2KN6 A;  2YVI A;  2G7R A;  4P4H A;  1D2Z B;  2NSN A;  2A5Y B;  4A2W A;  3EZQ B;  3J6J A;  4ZBW A;  2DBG A;  4O7Q A;  4IZ7 B;  2B1W A;  3LQQ A;  3YGS C;  4JQW A;  2LWD A;  4JUP A;  4N1L A;  2IB1 A;  1WH4 A;  2MPC A;  2N7Z A;  4IZ5 E;  4N1J A;  1C15 A;  1PN5 A;  2YU0 A;  3LQR A;  4RHW A;  2N1F A;  4O9L A;  4UZ0 A;  2LS7 A;  3MOP G;  4F44 A;  4P4H I;  1N3K A;  2N80 A;  4QOB A;  1DDF A;  1WMG A;  4M9X A;  2L9M A;  2DBF A;  2GF5 A;  1Z6T A;  2HM2 Q;  3CL3 A;  1UCP A;  3MOP K;  4E9M A;  4F42 A;  3J63 A;  1WXP A;  2BBZ A;  2DO9 A;  1CY5 A;  3QF2 A;  2KM6 A;  3MOP A;  2P1H A;  1YGO A;  1NGR A;  2MS7 A;  1A1W A;  2D96 A;  2N00 A;  1FAD A;  4NQK A;  2NZ7 A;  2NAQ A;  4IZA B;  4RHW E;  2M5V A;  2OF5 A;  4O6X A; 
#chains in the Genus database with same CATH topology
 1E3Y A;  4D8O A;  1A1Z A;  1DGN A;  2L6A A;  1E41 A;  2N83 A;  1ICH A;  1CWW A;  2YGS A;  2F1S A;  2A9I A;  4FH0 A;  4O9F A;  2MB9 A;  2N97 A;  2BBR A;  1D2Z A;  2OF5 H;  3T6P A;  2DBD A;  4M9S A;  2MJM A;  3EZQ A;  4DWN A;  2MS8 A;  4M9Z A;  4EWI A;  2DBH A;  2LWE A;  4LWD A;  4A2Q A;  2MN4 A;  2O71 A;  4N1K A;  2VGQ A;  3CRD A;  4I16 A;  3KAT A;  3YGS P;  2YQF A;  2KN6 A;  2YVI A;  2G7R A;  4P4H A;  1D2Z B;  2NSN A;  2A5Y B;  4A2W A;  3EZQ B;  3J6J A;  4ZBW A;  2DBG A;  4O7Q A;  4IZ7 B;  2B1W A;  3LQQ A;  3YGS C;  4JQW A;  2LWD A;  4JUP A;  4N1L A;  2IB1 A;  1WH4 A;  2MPC A;  2N7Z A;  4IZ5 E;  4N1J A;  1C15 A;  1PN5 A;  2YU0 A;  3LQR A;  4RHW A;  2N1F A;  4O9L A;  4UZ0 A;  2LS7 A;  3MOP G;  4F44 A;  4P4H I;  1N3K A;  2N80 A;  4QOB A;  1DDF A;  1WMG A;  4M9X A;  2L9M A;  2DBF A;  2GF5 A;  1Z6T A;  2HM2 Q;  3CL3 A;  1UCP A;  3MOP K;  4E9M A;  4F42 A;  3J63 A;  1WXP A;  2BBZ A;  2DO9 A;  1CY5 A;  3QF2 A;  2KM6 A;  3MOP A;  2P1H A;  1YGO A;  1NGR A;  2MS7 A;  1A1W A;  2D96 A;  2N00 A;  1FAD A;  2XV9 A;  4NQK A;  2NZ7 A;  2NAQ A;  4IZA B;  4RHW E;  2M5V A;  2OF5 A;  4O6X A; 
#chains in the Genus database with same CATH homology
 1E3Y A;  4D8O A;  1A1Z A;  1DGN A;  2L6A A;  1E41 A;  2N83 A;  1ICH A;  1CWW A;  2YGS A;  2F1S A;  2A9I A;  4FH0 A;  4O9F A;  2MB9 A;  2N97 A;  2BBR A;  1D2Z A;  2OF5 H;  3T6P A;  2DBD A;  4M9S A;  2MJM A;  3EZQ A;  4DWN A;  2MS8 A;  4M9Z A;  4EWI A;  2DBH A;  2LWE A;  4LWD A;  4A2Q A;  2MN4 A;  2O71 A;  4N1K A;  2VGQ A;  3CRD A;  4I16 A;  3KAT A;  3YGS P;  2YQF A;  2KN6 A;  2YVI A;  2G7R A;  4P4H A;  1D2Z B;  2NSN A;  2A5Y B;  4A2W A;  3EZQ B;  3J6J A;  4ZBW A;  2DBG A;  4O7Q A;  4IZ7 B;  2B1W A;  3LQQ A;  3YGS C;  4JQW A;  2LWD A;  4JUP A;  4N1L A;  2IB1 A;  1WH4 A;  2MPC A;  2N7Z A;  4IZ5 E;  4N1J A;  1C15 A;  1PN5 A;  2YU0 A;  3LQR A;  4RHW A;  2N1F A;  4O9L A;  4UZ0 A;  2LS7 A;  3MOP G;  4F44 A;  4P4H I;  1N3K A;  2N80 A;  4QOB A;  1DDF A;  1WMG A;  4M9X A;  2L9M A;  2DBF A;  2GF5 A;  1Z6T A;  2HM2 Q;  3CL3 A;  1UCP A;  3MOP K;  4E9M A;  4F42 A;  3J63 A;  1WXP A;  2BBZ A;  2DO9 A;  1CY5 A;  3QF2 A;  2KM6 A;  3MOP A;  2P1H A;  1YGO A;  1NGR A;  2MS7 A;  1A1W A;  2D96 A;  2N00 A;  1FAD A;  2XV9 A;  4NQK A;  2NZ7 A;  2NAQ A;  4IZA B;  4RHW E;  2M5V A;  2OF5 A;  4O6X A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...