1PO24

Poliovirus (type 1, mahoney) in complex with r77975, an inhibitor of viral replication
Total Genus 5
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
68
structure length
62
Chain Sequence
GAQVSSQKVGAHENSSTINYTTINYYRDSASNAASKQDFSQDPSKFTEPIKDVLIKTAPMLN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Ligand-induced conformational changes in poliovirus-antiviral drug complexes.
pubmed doi rcsb
molecule tags Virus
molecule keywords POLIOVIRUS TYPE 1 MAHONEY
total genus 5
structure length 62
sequence length 68
ec nomenclature ec 2.7.7.48: RNA-directed RNA polymerase.
pdb deposition date 1997-01-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
4 PF02226 Pico_P1A Picornavirus coat protein (VP4)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.80.10 Few Secondary Structures Irregular Rhinovirus 14, subunit 4 Picornavirus coat protein VP4 1po2400
1HXS4 1PO14 1R094 1RHI4 3J8F4 2RM24 1NCQD 1EV14 1D4M4 1MQTD 1RUC4 2RS34 1VBE4 1VBA4 1COV4 1EAH4 1VBC4 1BEV4 1RUG4 1NA1D 1VBD4 2R064 2R044 2R074 2RS14 4Q4W4 3JD74 2RS54 1HRI4 1RUJ4 1AR64 1PIV4 1VRH4 1AR84 1ASJ4 2RMU4 3JBG4 1AR74 1RUI4 1RUD4 1HRV4 4Q4V4 1VBB4 1RUF4 1PVC4 2RR14 1PO24 1K5MD 4RHV4 2HWC4 1RUH4 2HWB4 4GB34 2X5ID 4PDWD 1Z7S4 4Q4X4 1POV0 1RUE4 2PLV4 4Q4Y4 1R084 1H8TD 1RVF4 1AL24 1RMU4 1AR94 1OOPD
chains in the Genus database with same CATH superfamily
4YSYA 3J8F4 4YT0A 1NCQD 3AE8A 3VR9A 3GQKA 1COV4 2H88A 2WDVA 2R074 3AE9A 2PZSA 1AR64 2PY5A 1AR84 1ASJ4 2R7FA 5C3JA 1NEKA 1HRV4 1PVC4 1PO24 1ZOYA 4KX6A 4Q4X4 2PLV4 1H8TD 2WP9A 4YTNA 1OOPD 1HXS4 1RHI4 1EV14 3GQHA 3AE6A 1MQTD 2RS34 2PYLA 1VBA4 3SFEA 1EAH4 1NENA 1YQ4A 1VBD4 2R064 2R044 3SUCA 5C2TA 1KFYA 3JD74 3P4QA 1RUJ4 1PIV4 1VRH4 2WS3A 2PYJA 3AE2A 1RUD4 1KF6A 2RR14 1XHXA 1K5MD 4RHV4 3AE4A 3AEGA 2WDQA 2X5ID 3AEFA 2WDRA 4PDWD 3VRAA 2WU5A 4YTMA 3VR8A 1RMU4 1RVF4 1PO14 1R094 2WQYA 3P4RA 1D4M4 2ACZA 2WU2A 1RUC4 3AE3A 3AEEA 1VBE4 1XHZA 1RUG4 4YTPA 2EX3A 3P4SA 2RS14 1XI1A 4Q4W4 2FBWA 2RS54 1AR74 4Q4V4 1VBB4 1RUF4 2H89A 2B76A 1RUH4 2HWB4 3SFDA 1RUE4 3ABVA 1R084 1L0VA 3AE1A 3JBG4 3CIRA 1ZP0A 3AEDA 2RM24 3VRBA 4YSXA 2PW9A 4YSZA 1VBC4 1BEV4 1NA1D 3FI7A 1HRI4 4YXDA 3AE5A 2RMU4 1RUI4 3P4PA 2HWC4 4GB34 3AEBA 1Z7S4 3AECA 1POV0 4Q4Y4 3AEAA 1AL24 1YQ3A 1AR94 3AE7A
chains in the Genus database with same CATH topology
1HXS4 1PO14 1R094 1RHI4 3J8F4 2RM24 1NCQD 1EV14 1D4M4 1MQTD 1RUC4 2RS34 1VBE4 1VBA4 1COV4 1EAH4 1VBC4 1BEV4 1RUG4 1NA1D 1VBD4 2R064 2R044 2R074 2RS14 4Q4W4 3JD74 2RS54 1HRI4 1RUJ4 1AR64 1PIV4 1VRH4 1AR84 1ASJ4 2RMU4 3JBG4 1AR74 1RUI4 1RUD4 1HRV4 4Q4V4 1VBB4 1RUF4 1PVC4 2RR14 1PO24 1K5MD 4RHV4 2HWC4 1RUH4 2HWB4 4GB34 2X5ID 4PDWD 1Z7S4 4Q4X4 1POV0 1RUE4 2PLV4 4Q4Y4 1R084 1H8TD 1RVF4 1AL24 1RMU4 1AR94 1OOPD
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1HXS 4;  1PO1 4;  1R09 4;  1RHI 4;  3J8F 4;  2RM2 4;  1NCQ D;  1EV1 4;  1D4M 4;  1MQT D;  1RUC 4;  2RS3 4;  1VBE 4;  1VBA 4;  1COV 4;  1EAH 4;  1VBC 4;  1BEV 4;  1RUG 4;  1NA1 D;  1VBD 4;  2R06 4;  2R04 4;  2R07 4;  2RS1 4;  4Q4W 4;  3JD7 4;  2RS5 4;  1HRI 4;  1RUJ 4;  1AR6 4;  1PIV 4;  1VRH 4;  1AR8 4;  1ASJ 4;  2RMU 4;  3JBG 4;  1AR7 4;  1RUI 4;  1RUD 4;  1HRV 4;  4Q4V 4;  1VBB 4;  1RUF 4;  1PVC 4;  2RR1 4;  1PO2 4;  1K5M D;  4RHV 4;  2HWC 4;  1RUH 4;  2HWB 4;  4GB3 4;  2X5I D;  4PDW D;  1Z7S 4;  4Q4X 4;  1POV 0;  1RUE 4;  2PLV 4;  4Q4Y 4;  1R08 4;  1H8T D;  1RVF 4;  1AL2 4;  1RMU 4;  1AR9 4;  1OOP D; 
#chains in the Genus database with same CATH topology
 4YSY A;  3J8F 4;  4YT0 A;  1NCQ D;  3AE8 A;  3VR9 A;  3GQK A;  1COV 4;  2H88 A;  2WDV A;  2R07 4;  3AE9 A;  2PZS A;  1AR6 4;  2PY5 A;  1AR8 4;  1ASJ 4;  2R7F A;  5C3J A;  1NEK A;  1HRV 4;  1PVC 4;  1PO2 4;  1ZOY A;  4KX6 A;  4Q4X 4;  2PLV 4;  1H8T D;  2WP9 A;  4YTN A;  1OOP D;  1HXS 4;  1RHI 4;  1EV1 4;  3GQH A;  3AE6 A;  1MQT D;  2RS3 4;  2PYL A;  1VBA 4;  3SFE A;  1EAH 4;  1NEN A;  1YQ4 A;  1VBD 4;  2R06 4;  2R04 4;  3SUC A;  5C2T A;  1KFY A;  3JD7 4;  3P4Q A;  1RUJ 4;  1PIV 4;  1VRH 4;  2WS3 A;  2PYJ A;  3AE2 A;  1RUD 4;  1KF6 A;  2RR1 4;  1XHX A;  1K5M D;  4RHV 4;  3AE4 A;  3AEG A;  2WDQ A;  2X5I D;  3AEF A;  2WDR A;  4PDW D;  3VRA A;  2WU5 A;  4YTM A;  3VR8 A;  1RMU 4;  1RVF 4;  1PO1 4;  1R09 4;  2WQY A;  3P4R A;  1D4M 4;  2ACZ A;  2WU2 A;  1RUC 4;  3AE3 A;  3AEE A;  1VBE 4;  1XHZ A;  1RUG 4;  4YTP A;  2EX3 A;  3P4S A;  2RS1 4;  1XI1 A;  4Q4W 4;  2FBW A;  2RS5 4;  1AR7 4;  4Q4V 4;  1VBB 4;  1RUF 4;  2H89 A;  2B76 A;  1RUH 4;  2HWB 4;  3SFD A;  1RUE 4;  3ABV A;  1R08 4;  1L0V A;  3AE1 A;  3JBG 4;  3CIR A;  1ZP0 A;  3AED A;  2RM2 4;  3VRB A;  4YSX A;  2PW9 A;  4YSZ A;  1VBC 4;  1BEV 4;  1NA1 D;  3FI7 A;  1HRI 4;  4YXD A;  3AE5 A;  2RMU 4;  1RUI 4;  3P4P A;  2HWC 4;  4GB3 4;  3AEB A;  1Z7S 4;  3AEC A;  1POV 0;  4Q4Y 4;  3AEA A;  1AL2 4;  1YQ3 A;  1AR9 4;  3AE7 A; 
#chains in the Genus database with same CATH homology
 1HXS 4;  1PO1 4;  1R09 4;  1RHI 4;  3J8F 4;  2RM2 4;  1NCQ D;  1EV1 4;  1D4M 4;  1MQT D;  1RUC 4;  2RS3 4;  1VBE 4;  1VBA 4;  1COV 4;  1EAH 4;  1VBC 4;  1BEV 4;  1RUG 4;  1NA1 D;  1VBD 4;  2R06 4;  2R04 4;  2R07 4;  2RS1 4;  4Q4W 4;  3JD7 4;  2RS5 4;  1HRI 4;  1RUJ 4;  1AR6 4;  1PIV 4;  1VRH 4;  1AR8 4;  1ASJ 4;  2RMU 4;  3JBG 4;  1AR7 4;  1RUI 4;  1RUD 4;  1HRV 4;  4Q4V 4;  1VBB 4;  1RUF 4;  1PVC 4;  2RR1 4;  1PO2 4;  1K5M D;  4RHV 4;  2HWC 4;  1RUH 4;  2HWB 4;  4GB3 4;  2X5I D;  4PDW D;  1Z7S 4;  4Q4X 4;  1POV 0;  1RUE 4;  2PLV 4;  4Q4Y 4;  1R08 4;  1H8T D;  1RVF 4;  1AL2 4;  1RMU 4;  1AR9 4;  1OOP D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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