1PTYA

Crystal structure of protein tyrosine phosphatase 1b complexed with two phosphotyrosine molecules
Total Genus 107
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
107
sequence length
298
structure length
298
Chain Sequence
EMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHSSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHEDL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Identification of a second aryl phosphate-binding site in protein-tyrosine phosphatase 1B: a paradigm for inhibitor design.
pubmed doi rcsb
molecule keywords PROTEIN TYROSINE PHOSPHATASE 1B
molecule tags Hydrolase
source organism Homo sapiens
total genus 107
structure length 298
sequence length 298
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 1997-01-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 1ptyA00
2OC3A 1PH0A 2H02A 4KYRA 1FPZA 5K22A 1NO6A 4QBWA 4ERCA 2VEWA 1WAXA 4NX8A 4WU3A 1ONZA 1QZ0A 2CNEA 3QCGA 1U25A 2HC1A 2HC2A 2I3RA 1OEUA 1Q1MA 1U26A 1XRIA 4QUNA 3N0AA 2CNFA 2HY3A 3H2XA 2C7SA 2F6TA 1T48A 1XBOA 2CNIA 2F46A 2F6VA 1G4WR 2BGDA 3SMEA 1C84A 4JNBA 2QCJA 5HDEA 2G59A 1P15A 3QCFA 1G1HA 5IBMA 2CFVA 2HB1A 1FQ1A 1OHEA 2ESBA 3D44A 2CM7A 3A5JA 2BGEA 4GWFA 2SHPA 4D3RA 1M3GA 1OEOX 1EENA 1J4XA 2I6IA 3EAXA 4GFUA 2GWOA 2VEUA 1NWLA 1YGRA 3AWGA 2B4PA 2I6MA 4D3QA 2HXPA 1ZZWA 3I36A 1YGUA 1RPMA 2M3VA 5BX1A 1NWEA 2PI7A 1BZCA 5I6VA 1Q6SA 1LARA 4Y2EA 5LXQB 1XXPA 1Q6JA 2NTAA 5K9VA 1PYNA 4GS0A 4WTYA 3MOZA 2A3KA 3MOWA 5KABA 3QCKA 4QAPA 2QBRA 3QCIA 4RKKA 2MBCA 3S3EA 1OESA 2AHSA 1G4US 4NWGA 1C85A 2AZRA 3U96A 2F71A 2R0BA 1QXKA 5AWXA 5KA8A 5KA4A 5KADA 1JLNA 1BZHA 2H03A 1NL9A 3MMJA 2NLKA 3I7ZA 2B07A 2QDMA 3S3KA 3RO1A 4B04A 2VEXA 2HCMA 2I6JA 1WCHA 1PA1A 3D1QA 1YPTA 4BPCA 2NZ6A 2ZN7A 3GXHA 2BV5A 3ZV2A 3BM8A 2IMGA 3ZMPA 2Q05A 4QBEA 5KA0A 2BIJA 1YTNA 2HVLA 5K24A 2OZ5A 4OHDA 4DGPA 2FJNA 4NYHA 3F99A 5EHPA 2CMBA 5BZXA 3V0HA 2I4GA 1PTYA 2FJMA 2PSZA 4OHLA 2PA5A 5KA9A 2JJDA 2I4EA 2B49A 1NNYA 2GJTA 1RXDA 3RZ2A 2ZMMA 1T4JA 1GFYA 2QBQA 2I1YA 2E0TA 4GE6A 4WU2A 5BZZA 2F6ZA 2NT2A 3PS5A 2NV5A 4Z6BA 3QCCA 1PTUA 3O4TA 2CM8A 1OETA 3QKQA 3V0DA 2CJZA 3V0EA 1KAKA 5KA3A 5EHRA 2I4HA 3QCNA 4AZ1A 3RGQA 3BLTA 4TVVA 1NZ7A 1YFOA 1Q6TA 5K9WA 3QKPA 4DGXA 2QDCA 3AWFA 2H04A 1ECVA 5KACA 2CMCA 3D1HA 3D9CA 4RDDA 1LQFA 4ZN5A 1C88A 2P6XA 1FPRA 3QCHA 2J16A 3ZM2A 3EMUA 3QCLA 1XM2A 4HJPA 1ZC0A 2C46A 2H4KA 4S0GA 1D5RA 3V0IA 4PYHA 1G7FA 4JBCA 4R0TA 2I6PA 4YR8B 2QBSA 1T49A 3LJ8A 4ICZA 3I80A 3S3HA 3CM3A 2Y96A 4H1OA 4HRFA 1YTWA 2QBPA 3CWEA 1BZJA 1PTVA 2NT7A 3S4OA 4ZRTA 3ZM3A 1VHRA 2PBNA 3D42A 1I9TA 4QAHA 3EZZA 3BRHA 3EB1A 3A5KA 4OHHA 5MMZB 2GP0A 2VEVA 3M4UA 4H34A 1OEVA 4Y14A 4RI4A 2I5XA 5KAAA 2G6ZA 1ZCKA 2YDUA 4KI9A 1YN9A 1U24A 5BUGA 1L8GA 3QCMA 2I42A 3O5XA 1JF7A 3OLRA 5J8RA 2CM2A 4R30A 3ZM1A 4RI5A 2P4DA 1Q6PA 2B3OA 2CNGA 2HNPA 3SR9A 1G7GA 5KA2A 1I57A 3QCJA 1Q6NA 2I3UA 1OHDA 5K23A 4NWFA 3S3FA 3ZM0A 4PVGA 3B7OA 3QCDA 1YZ4A 1EEOA 2CM3A 1PXHA 2RF6A 2F6YA 3ZMQA 3V0GA 1Q6MA 4ZI4A 2OUDA 1G1GA 4OHEA 5GTJA 4JMJA 2H4GA 3F9BA 4RHGA 3GXGA 1YWFA 1LYVA 3S4EA 4BJOA 2CMAA 4RH9A 3F41A 3OMHA 3EU0A 2HNQA 2VEYA 2FH7A 3F9AA 4NNDA 1L8KA 3NMEA 2B4OA 2PQ5A 1OHCA 2A8BA 5K25A 2I75A 2F6FA 1C87A 1ONYA 4RH5A 2OOQA 3QCBA 2WGPA 2Y2FA 2QEPA 3QCEA 1XXVA 2F6WA 1OEMX 5KA7A 1PA9A 1WRMA 1GWZA 1ZCLA 1SUGA 3O4SA 4KYQA 2QCTA 2QDPA 1MKPA 2BZLA 4D3PA 1KAVA 3O3LA 2H4VA 5KA1A 2J17A 2CNHA 4R0SA 1R6HA 4WOHA 2B4SA 4MBBA 1I9SA 4IKCA 2F70A 5M43A 3D1OA 1AAXA 4YAAA 4JMKA 3RGOA 4GE5A 1V3AA 3F81A 2Q47A 1C83A 1A5YA 1G1FA 1X24A 3V0JA 1PTTA 4J51A 1YTSA 2J16B 3O4UA 4GRYA 2I6OA 4GE2A 4GFVA 3V0FA 3BLUA 4GRZA 5IBSA 2B4UA 1C86A 3AWEA 4HJQA 2DXPA 4QUMA 4I8NA 2PT0A 4OHIA
chains in the Genus database with same CATH superfamily
1JBVA 2UUOA 2OC3A 1PH0A 2H02A 4KYRA 1FPZA 5K22A 1NO6A 4QBWA 4ERCA 2VEWA 1WAXA 4NX8A 4WU3A 1ONZA 1QZ0A 5A5EA 2CNEA 3QCGA 1U25A 2HC1A 2HC2A 2I3RA 1OEUA 1Q1MA 1U26A 1XRIA 4QUNA 1P31A 3N0AA 2CNFA 2WJPA 2HY3A 3H2XA 2C7SA 2F6TA 1T48A 1XBOA 2JFFA 2CNIA 2F46A 2F6VA 1G4WR 2BGDA 3SMEA 1C84A 4JNBA 2QCJA 5HDEA 2G59A 1P15A 3QCFA 1G1HA 5IBMA 2CFVA 2HB1A 1FQ1A 1OHEA 3QCZA 1W78A 2ESBA 4QF5A 3D44A 2CM7A 3A5JA 2BGEA 4ZIYA 4GWFA 2SHPA 4D3RA 1M3GA 2VTDA 1E8CA 1OEOX 1EENA 1J4XA 2I6IA 3EAXA 4GFUA 2GWOA 2VEUA 1NWLA 2AM1A 2VORA 1YGRA 3AWGA 2B4PA 2I6MA 4D3QA 2HXPA 1ZZWA 3I36A 1YGUA 1RPMA 2M3VA 5BX1A 1NWEA 2PI7A 1BZCA 5I6VA 1Q6SA 1LARA 4Y2EA 5LXQB 1XXPA 1Q6JA 2NTAA 5K9VA 2JFHA 1PYNA 4GS0A 4WTYA 3NRSA 3MOZA 2A3KA 3MOWA 5KABA 3QCKA 4QAPA 2QBRA 3QCIA 4RKKA 2MBCA 3S3EA 1OESA 3UAGA 2VTEA 2AHSA 1G4US 4NWGA 1W7KA 1C85A 2AZRA 3U96A 2F71A 2R0BA 1QXKA 5AWXA 5KA8A 3HN7A 5KA4A 5KADA 1BZHA 1JLNA 2H03A 1NL9A 3MMJA 2NLKA 2Y66A 3I7ZA 4CVMA 2B07A 2QDMA 3S3KA 3RO1A 4B04A 2VEXA 2HCMA 2I6JA 1WCHA 1PA1A 3D1QA 1YPTA 4BPCA 4CVKA 2NZ6A 2ZN7A 1E0DA 3GXHA 2BV5A 3ZV2A 3BM8A 2GCAA 2IMGA 3ZMPA 2Q05A 3ZL8A 4QBEA 5KA0A 2BIJA 2Y67A 4C12A 1YTNA 2HVLA 4CVLA 3ZM6A 5K24A 2OZ5A 4OHDA 4DGPA 2FJNA 4NYHA 2JFGA 3F99A 5EHPA 2CMBA 5BZXA 3V0HA 2I4GA 1PTYA 2FJMA 2PSZA 4OHLA 2PA5A 5KA9A 1GG4A 4QDIA 2JJDA 3LK7A 2I4EA 2B49A 1NNYA 2GJTA 1RXDA 3RZ2A 2ZMMA 1T4JA 2AM2A 1GFYA 1GQQA 2I1YA 2QBQA 2E0TA 4GE6A 4WU2A 5BZZA 2F6ZA 2NT2A 3PS5A 2NV5A 4Z6BA 3QCCA 1PTUA 3O4TA 2CM8A 1OETA 3QKQA 3V0DA 2CJZA 2VOSA 3V0EA 2GCBA 4C13A 2Y68A 1KAKA 5KA3A 5EHRA 2I4HA 3QCNA 4AZ1A 3RGQA 1P3DA 3BLTA 4TVVA 1NZ7A 1YFOA 1Q6TA 5K9WA 3QKPA 4DGXA 2QDCA 3AWFA 4BUCA 2H04A 1ECVA 5KACA 2CMCA 3D1HA 2Y1OA 3D9CA 4RDDA 4BUBA 1LQFA 4ZN5A 1C88A 2P6XA 1FPRA 3QCHA 2J16A 3ZM2A 3EMUA 3QCLA 1XM2A 4HJPA 1ZC0A 2C46A 2H4KA 4S0GA 1D5RA 3V0IA 4PYHA 1G7FA 4JBCA 4R0TA 2I6PA 4YR8B 2QBSA 1T49A 2X5OA 3LJ8A 4ICZA 3I80A 3S3HA 3CM3A 2Y96A 4H1OA 4HRFA 1YTWA 2QBPA 3CWEA 4HV4A 1BZJA 1PTVA 2NT7A 3S4OA 4ZRTA 3ZM3A 1VHRA 2PBNA 3D42A 1I9TA 4QAHA 3EZZA 3BRHA 3EB1A 3A5KA 4OHHA 5MMZB 2GP0A 2VEVA 3M4UA 4H34A 1OEVA 4Y14A 4RI4A 2I5XA 5KAAA 2G6ZA 1ZCKA 2YDUA 4KI9A 1YN9A 2XPCA 1U24A 5BUGA 1L8GA 3QCMA 2I42A 3O5XA 1JF7A 3OLRA 5J8RA 2CM2A 4R30A 3ZM1A 4RI5A 2P4DA 1Q6PA 2B3OA 2CNGA 2HNPA 3SR9A 1G7GA 5KA2A 1I57A 3QCJA 1Q6NA 2I3UA 1OHDA 5K23A 4NWFA 3S3FA 3ZM0A 4PVGA 3B7OA 3QCDA 1YZ4A 1EEOA 2CM3A 1PXHA 2RF6A 2F6YA 3ZMQA 3MVNA 3V0GA 1Q6MA 4ZI4A 2OUDA 1G1GA 2UAGA 4OHEA 3ZM5A 5GTJA 4JMJA 2H4GA 2XJAA 3F9BA 4RHGA 3GXGA 1YWFA 1LYVA 3S4EA 4BJOA 2CMAA 4RH9A 3F41A 3OMHA 3EU0A 2HNQA 2VEYA 2FH7A 2GC6A 3F9AA 4NNDA 2WTZA 1J6UA 1L8KA 1FGSA 3NMEA 2B4OA 2PQ5A 1OHCA 2A8BA 5K25A 2I75A 2F6FA 1C87A 1ONYA 4RH5A 2OOQA 3QCBA 2WGPA 2Y2FA 2QEPA 3QCEA 1XXVA 2F6WA 1OEMX 5KA7A 1PA9A 1WRMA 1GWZA 1ZCLA 1SUGA 3O4SA 4KYQA 2F00A 3N2AA 2QCTA 2QDPA 1MKPA 2BZLA 4D3PA 1KAVA 2GC5A 3O3LA 2H4VA 5KA1A 2J17A 2CNHA 4R0SA 1R6HA 4WOHA 2B4SA 4MBBA 1I9SA 4IKCA 2F70A 5M43A 3D1OA 1AAXA 4YAAA 1EEHA 4JMKA 3RGOA 4GE5A 1V3AA 1GQYA 3F81A 2Q47A 1C83A 1A5YA 1G1FA 1X24A 3V0JA 1JBWA 1PTTA 4J51A 1YTSA 2J16B 3O4UA 4GRYA 2I6OA 2PT0A 4GE2A 4GFVA 1UAGA 3V0FA 3BLUA 4GRZA 4UAGA 5IBSA 2B4UA 1C86A 3AWEA 5A5FA 4HJQA 2DXPA 4QUMA 4I8NA 3PYZA 1O5ZA 2UUPA 4OHIA
chains in the Genus database with same CATH topology
2OC3A 1PH0A 2H02A 4KYRA 1FPZA 5K22A 1NO6A 4QBWA 4ERCA 2VEWA 1WAXA 4NX8A 4WU3A 1ONZA 1QZ0A 2CNEA 3QCGA 1U25A 2HC1A 2HC2A 2I3RA 1OEUA 1Q1MA 1U26A 1XRIA 4QUNA 3N0AA 2CNFA 2HY3A 3H2XA 2C7SA 2F6TA 1T48A 1XBOA 2CNIA 2F46A 2F6VA 1G4WR 2BGDA 3SMEA 1C84A 4JNBA 2QCJA 5HDEA 2G59A 1P15A 3QCFA 1G1HA 5IBMA 2CFVA 2HB1A 1FQ1A 1OHEA 2ESBA 3D44A 2CM7A 3A5JA 2BGEA 4GWFA 2SHPA 4D3RA 1M3GA 1OEOX 1EENA 1J4XA 2I6IA 3EAXA 4GFUA 2GWOA 2VEUA 1NWLA 1YGRA 3AWGA 2B4PA 2I6MA 4D3QA 2HXPA 1ZZWA 3I36A 1YGUA 1RPMA 2M3VA 5BX1A 1NWEA 2PI7A 1BZCA 5I6VA 1Q6SA 1LARA 4Y2EA 5LXQB 1XXPA 1Q6JA 2NTAA 5K9VA 1PYNA 4GS0A 4WTYA 3MOZA 2A3KA 3MOWA 5KABA 3QCKA 4QAPA 2QBRA 3QCIA 4RKKA 2MBCA 3S3EA 1OESA 2AHSA 1G4US 4NWGA 1C85A 2AZRA 3U96A 2F71A 2R0BA 1QXKA 5AWXA 5KA8A 5KA4A 5KADA 1JLNA 1BZHA 2H03A 1NL9A 3MMJA 2NLKA 3I7ZA 2B07A 2QDMA 3S3KA 3RO1A 4B04A 2VEXA 2HCMA 2I6JA 1WCHA 1PA1A 3D1QA 1YPTA 4BPCA 2NZ6A 2ZN7A 3GXHA 2BV5A 3ZV2A 3BM8A 2IMGA 3ZMPA 2Q05A 4QBEA 5KA0A 2BIJA 1YTNA 2HVLA 5K24A 2OZ5A 4OHDA 4DGPA 2FJNA 4NYHA 3F99A 5EHPA 2CMBA 5BZXA 3V0HA 2I4GA 1PTYA 2FJMA 2PSZA 4OHLA 2PA5A 5KA9A 2JJDA 2I4EA 2B49A 1NNYA 2GJTA 1RXDA 3RZ2A 2ZMMA 1T4JA 1GFYA 2QBQA 2I1YA 2E0TA 4GE6A 4WU2A 5BZZA 2F6ZA 2NT2A 3PS5A 2NV5A 4Z6BA 3QCCA 1PTUA 3O4TA 2CM8A 1OETA 3QKQA 3V0DA 2CJZA 3V0EA 1KAKA 5KA3A 5EHRA 2I4HA 3QCNA 4AZ1A 3RGQA 3BLTA 4TVVA 1NZ7A 1YFOA 1Q6TA 5K9WA 3QKPA 4DGXA 2QDCA 3AWFA 2H04A 1ECVA 5KACA 2CMCA 3D1HA 3D9CA 4RDDA 1LQFA 4ZN5A 1C88A 2P6XA 1FPRA 3QCHA 2J16A 3ZM2A 3EMUA 3QCLA 1XM2A 4HJPA 1ZC0A 2C46A 2H4KA 4S0GA 1D5RA 3V0IA 4PYHA 1G7FA 4JBCA 4R0TA 2I6PA 4YR8B 2QBSA 1T49A 3LJ8A 4ICZA 3I80A 3S3HA 3CM3A 2Y96A 4H1OA 4HRFA 1YTWA 2QBPA 3CWEA 1BZJA 1PTVA 2NT7A 3S4OA 4ZRTA 3ZM3A 1VHRA 2PBNA 3D42A 1I9TA 4QAHA 3EZZA 3BRHA 3EB1A 3A5KA 4OHHA 5MMZB 2GP0A 2VEVA 3M4UA 4H34A 1OEVA 4Y14A 4RI4A 2I5XA 5KAAA 2G6ZA 1ZCKA 2YDUA 4KI9A 1YN9A 1U24A 5BUGA 1L8GA 3QCMA 2I42A 3O5XA 1JF7A 3OLRA 5J8RA 2CM2A 4R30A 3ZM1A 4RI5A 2P4DA 1Q6PA 2B3OA 2CNGA 2HNPA 3SR9A 1G7GA 5KA2A 1I57A 3QCJA 1Q6NA 2I3UA 1OHDA 5K23A 4NWFA 3S3FA 3ZM0A 4PVGA 3B7OA 3QCDA 1YZ4A 1EEOA 2CM3A 1PXHA 2RF6A 2F6YA 3ZMQA 3V0GA 1Q6MA 4ZI4A 2OUDA 1G1GA 4OHEA 5GTJA 4JMJA 2H4GA 3F9BA 4RHGA 3GXGA 1YWFA 1LYVA 3S4EA 4BJOA 2CMAA 4RH9A 3F41A 3OMHA 3EU0A 2HNQA 2VEYA 2FH7A 3F9AA 4NNDA 1L8KA 3NMEA 2B4OA 2PQ5A 1OHCA 2A8BA 5K25A 2I75A 2F6FA 1C87A 1ONYA 4RH5A 2OOQA 3QCBA 2WGPA 2Y2FA 2QEPA 3QCEA 1XXVA 2F6WA 1OEMX 5KA7A 1PA9A 1WRMA 1GWZA 1ZCLA 1SUGA 3O4SA 4KYQA 2QCTA 2QDPA 1MKPA 2BZLA 4D3PA 1KAVA 3O3LA 2H4VA 5KA1A 2J17A 2CNHA 4R0SA 1R6HA 4WOHA 2B4SA 4MBBA 1I9SA 4IKCA 2F70A 5M43A 3D1OA 1AAXA 4YAAA 4JMKA 3RGOA 4GE5A 1V3AA 3F81A 2Q47A 1C83A 1A5YA 1G1FA 1X24A 3V0JA 1PTTA 4J51A 1YTSA 2J16B 3O4UA 4GRYA 2I6OA 4GE2A 4GFVA 3V0FA 3BLUA 4GRZA 5IBSA 2B4UA 1C86A 3AWEA 4HJQA 2DXPA 4QUMA 4I8NA 2PT0A 4OHIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OC3 A;  1PH0 A;  2H02 A;  4KYR A;  1FPZ A;  5K22 A;  1NO6 A;  4QBW A;  4ERC A;  2VEW A;  1WAX A;  4NX8 A;  4WU3 A;  1ONZ A;  1QZ0 A;  2CNE A;  3QCG A;  1U25 A;  2HC1 A;  2HC2 A;  2I3R A;  1OEU A;  1Q1M A;  1U26 A;  1XRI A;  4QUN A;  3N0A A;  2CNF A;  2HY3 A;  3H2X A;  2C7S A;  2F6T A;  1T48 A;  1XBO A;  2CNI A;  2F46 A;  2F6V A;  1G4W R;  2BGD A;  3SME A;  1C84 A;  4JNB A;  2QCJ A;  5HDE A;  2G59 A;  1P15 A;  3QCF A;  1G1H A;  5IBM A;  2CFV A;  2HB1 A;  1FQ1 A;  1OHE A;  2ESB A;  3D44 A;  2CM7 A;  3A5J A;  2BGE A;  4GWF A;  2SHP A;  4D3R A;  1M3G A;  1OEO X;  1EEN A;  1J4X A;  2I6I A;  3EAX A;  4GFU A;  2GWO A;  2VEU A;  1NWL A;  1YGR A;  3AWG A;  2B4P A;  2I6M A;  4D3Q A;  2HXP A;  1ZZW A;  3I36 A;  1YGU A;  1RPM A;  2M3V A;  5BX1 A;  1NWE A;  2PI7 A;  1BZC A;  5I6V A;  1Q6S A;  1LAR A;  4Y2E A;  5LXQ B;  1XXP A;  1Q6J A;  2NTA A;  5K9V A;  1PYN A;  4GS0 A;  4WTY A;  3MOZ A;  2A3K A;  3MOW A;  5KAB A;  3QCK A;  4QAP A;  2QBR A;  3QCI A;  4RKK A;  2MBC A;  3S3E A;  1OES A;  2AHS A;  1G4U S;  4NWG A;  1C85 A;  2AZR A;  3U96 A;  2F71 A;  2R0B A;  1QXK A;  5AWX A;  5KA8 A;  5KA4 A;  5KAD A;  1JLN A;  1BZH A;  2H03 A;  1NL9 A;  3MMJ A;  2NLK A;  3I7Z A;  2B07 A;  2QDM A;  3S3K A;  3RO1 A;  4B04 A;  2VEX A;  2HCM A;  2I6J A;  1WCH A;  1PA1 A;  3D1Q A;  1YPT A;  4BPC A;  2NZ6 A;  2ZN7 A;  3GXH A;  2BV5 A;  3ZV2 A;  3BM8 A;  2IMG A;  3ZMP A;  2Q05 A;  4QBE A;  5KA0 A;  2BIJ A;  1YTN A;  2HVL A;  5K24 A;  2OZ5 A;  4OHD A;  4DGP A;  2FJN A;  4NYH A;  3F99 A;  5EHP A;  2CMB A;  5BZX A;  3V0H A;  2I4G A;  1PTY A;  2FJM A;  2PSZ A;  4OHL A;  2PA5 A;  5KA9 A;  2JJD A;  2I4E A;  2B49 A;  1NNY A;  2GJT A;  1RXD A;  3RZ2 A;  2ZMM A;  1T4J A;  1GFY A;  2QBQ A;  2I1Y A;  2E0T A;  4GE6 A;  4WU2 A;  5BZZ A;  2F6Z A;  2NT2 A;  3PS5 A;  2NV5 A;  4Z6B A;  3QCC A;  1PTU A;  3O4T A;  2CM8 A;  1OET A;  3QKQ A;  3V0D A;  2CJZ A;  3V0E A;  1KAK A;  5KA3 A;  5EHR A;  2I4H A;  3QCN A;  4AZ1 A;  3RGQ A;  3BLT A;  4TVV A;  1NZ7 A;  1YFO A;  1Q6T A;  5K9W A;  3QKP A;  4DGX A;  2QDC A;  3AWF A;  2H04 A;  1ECV A;  5KAC A;  2CMC A;  3D1H A;  3D9C A;  4RDD A;  1LQF A;  4ZN5 A;  1C88 A;  2P6X A;  1FPR A;  3QCH A;  2J16 A;  3ZM2 A;  3EMU A;  3QCL A;  1XM2 A;  4HJP A;  1ZC0 A;  2C46 A;  2H4K A;  4S0G A;  1D5R A;  3V0I A;  4PYH A;  1G7F A;  4JBC A;  4R0T A;  2I6P A;  4YR8 B;  2QBS A;  1T49 A;  3LJ8 A;  4ICZ A;  3I80 A;  3S3H A;  3CM3 A;  2Y96 A;  4H1O A;  4HRF A;  1YTW A;  2QBP A;  3CWE A;  1BZJ A;  1PTV A;  2NT7 A;  3S4O A;  4ZRT A;  3ZM3 A;  1VHR A;  2PBN A;  3D42 A;  1I9T A;  4QAH A;  3EZZ A;  3BRH A;  3EB1 A;  3A5K A;  4OHH A;  5MMZ B;  2GP0 A;  2VEV A;  3M4U A;  4H34 A;  1OEV A;  4Y14 A;  4RI4 A;  2I5X A;  5KAA A;  2G6Z A;  1ZCK A;  2YDU A;  4KI9 A;  1YN9 A;  1U24 A;  5BUG A;  1L8G A;  3QCM A;  2I42 A;  3O5X A;  1JF7 A;  3OLR A;  5J8R A;  2CM2 A;  4R30 A;  3ZM1 A;  4RI5 A;  2P4D A;  1Q6P A;  2B3O A;  2CNG A;  2HNP A;  3SR9 A;  1G7G A;  5KA2 A;  1I57 A;  3QCJ A;  1Q6N A;  2I3U A;  1OHD A;  5K23 A;  4NWF A;  3S3F A;  3ZM0 A;  4PVG A;  3B7O A;  3QCD A;  1YZ4 A;  1EEO A;  2CM3 A;  1PXH A;  2RF6 A;  2F6Y A;  3ZMQ A;  3V0G A;  1Q6M A;  4ZI4 A;  2OUD A;  1G1G A;  4OHE A;  5GTJ A;  4JMJ A;  2H4G A;  3F9B A;  4RHG A;  3GXG A;  1YWF A;  1LYV A;  3S4E A;  4BJO A;  2CMA A;  4RH9 A;  3F41 A;  3OMH A;  3EU0 A;  2HNQ A;  2VEY A;  2FH7 A;  3F9A A;  4NND A;  1L8K A;  3NME A;  2B4O A;  2PQ5 A;  1OHC A;  2A8B A;  5K25 A;  2I75 A;  2F6F A;  1C87 A;  1ONY A;  4RH5 A;  2OOQ A;  3QCB A;  2WGP A;  2Y2F A;  2QEP A;  3QCE A;  1XXV A;  2F6W A;  1OEM X;  5KA7 A;  1PA9 A;  1WRM A;  1GWZ A;  1ZCL A;  1SUG A;  3O4S A;  4KYQ A;  2QCT A;  2QDP A;  1MKP A;  2BZL A;  4D3P A;  1KAV A;  3O3L A;  2H4V A;  5KA1 A;  2J17 A;  2CNH A;  4R0S A;  1R6H A;  4WOH A;  2B4S A;  4MBB A;  1I9S A;  4IKC A;  2F70 A;  5M43 A;  3D1O A;  1AAX A;  4YAA A;  4JMK A;  3RGO A;  4GE5 A;  1V3A A;  3F81 A;  2Q47 A;  1C83 A;  1A5Y A;  1G1F A;  1X24 A;  3V0J A;  1PTT A;  4J51 A;  1YTS A;  2J16 B;  3O4U A;  4GRY A;  2I6O A;  4GE2 A;  4GFV A;  3V0F A;  3BLU A;  4GRZ A;  5IBS A;  2B4U A;  1C86 A;  3AWE A;  4HJQ A;  2DXP A;  4QUM A;  4I8N A;  2PT0 A;  4OHI A; 
#chains in the Genus database with same CATH topology
 1JBV A;  2UUO A;  2OC3 A;  1PH0 A;  2H02 A;  4KYR A;  1FPZ A;  5K22 A;  1NO6 A;  4QBW A;  4ERC A;  2VEW A;  1WAX A;  4NX8 A;  4WU3 A;  1ONZ A;  1QZ0 A;  5A5E A;  2CNE A;  3QCG A;  1U25 A;  2HC1 A;  2HC2 A;  2I3R A;  1OEU A;  1Q1M A;  1U26 A;  1XRI A;  4QUN A;  1P31 A;  3N0A A;  2CNF A;  2WJP A;  2HY3 A;  3H2X A;  2C7S A;  2F6T A;  1T48 A;  1XBO A;  2JFF A;  2CNI A;  2F46 A;  2F6V A;  1G4W R;  2BGD A;  3SME A;  1C84 A;  4JNB A;  2QCJ A;  5HDE A;  2G59 A;  1P15 A;  3QCF A;  1G1H A;  5IBM A;  2CFV A;  2HB1 A;  1FQ1 A;  1OHE A;  3QCZ A;  1W78 A;  2ESB A;  4QF5 A;  3D44 A;  2CM7 A;  3A5J A;  2BGE A;  4ZIY A;  4GWF A;  2SHP A;  4D3R A;  1M3G A;  2VTD A;  1E8C A;  1OEO X;  1EEN A;  1J4X A;  2I6I A;  3EAX A;  4GFU A;  2GWO A;  2VEU A;  1NWL A;  2AM1 A;  2VOR A;  1YGR A;  3AWG A;  2B4P A;  2I6M A;  4D3Q A;  2HXP A;  1ZZW A;  3I36 A;  1YGU A;  1RPM A;  2M3V A;  5BX1 A;  1NWE A;  2PI7 A;  1BZC A;  5I6V A;  1Q6S A;  1LAR A;  4Y2E A;  5LXQ B;  1XXP A;  1Q6J A;  2NTA A;  5K9V A;  2JFH A;  1PYN A;  4GS0 A;  4WTY A;  3NRS A;  3MOZ A;  2A3K A;  3MOW A;  5KAB A;  3QCK A;  4QAP A;  2QBR A;  3QCI A;  4RKK A;  2MBC A;  3S3E A;  1OES A;  3UAG A;  2VTE A;  2AHS A;  1G4U S;  4NWG A;  1W7K A;  1C85 A;  2AZR A;  3U96 A;  2F71 A;  2R0B A;  1QXK A;  5AWX A;  5KA8 A;  3HN7 A;  5KA4 A;  5KAD A;  1BZH A;  1JLN A;  2H03 A;  1NL9 A;  3MMJ A;  2NLK A;  2Y66 A;  3I7Z A;  4CVM A;  2B07 A;  2QDM A;  3S3K A;  3RO1 A;  4B04 A;  2VEX A;  2HCM A;  2I6J A;  1WCH A;  1PA1 A;  3D1Q A;  1YPT A;  4BPC A;  4CVK A;  2NZ6 A;  2ZN7 A;  1E0D A;  3GXH A;  2BV5 A;  3ZV2 A;  3BM8 A;  2GCA A;  2IMG A;  3ZMP A;  2Q05 A;  3ZL8 A;  4QBE A;  5KA0 A;  2BIJ A;  2Y67 A;  4C12 A;  1YTN A;  2HVL A;  4CVL A;  3ZM6 A;  5K24 A;  2OZ5 A;  4OHD A;  4DGP A;  2FJN A;  4NYH A;  2JFG A;  3F99 A;  5EHP A;  2CMB A;  5BZX A;  3V0H A;  2I4G A;  1PTY A;  2FJM A;  2PSZ A;  4OHL A;  2PA5 A;  5KA9 A;  1GG4 A;  4QDI A;  2JJD A;  3LK7 A;  2I4E A;  2B49 A;  1NNY A;  2GJT A;  1RXD A;  3RZ2 A;  2ZMM A;  1T4J A;  2AM2 A;  1GFY A;  1GQQ A;  2I1Y A;  2QBQ A;  2E0T A;  4GE6 A;  4WU2 A;  5BZZ A;  2F6Z A;  2NT2 A;  3PS5 A;  2NV5 A;  4Z6B A;  3QCC A;  1PTU A;  3O4T A;  2CM8 A;  1OET A;  3QKQ A;  3V0D A;  2CJZ A;  2VOS A;  3V0E A;  2GCB A;  4C13 A;  2Y68 A;  1KAK A;  5KA3 A;  5EHR A;  2I4H A;  3QCN A;  4AZ1 A;  3RGQ A;  1P3D A;  3BLT A;  4TVV A;  1NZ7 A;  1YFO A;  1Q6T A;  5K9W A;  3QKP A;  4DGX A;  2QDC A;  3AWF A;  4BUC A;  2H04 A;  1ECV A;  5KAC A;  2CMC A;  3D1H A;  2Y1O A;  3D9C A;  4RDD A;  4BUB A;  1LQF A;  4ZN5 A;  1C88 A;  2P6X A;  1FPR A;  3QCH A;  2J16 A;  3ZM2 A;  3EMU A;  3QCL A;  1XM2 A;  4HJP A;  1ZC0 A;  2C46 A;  2H4K A;  4S0G A;  1D5R A;  3V0I A;  4PYH A;  1G7F A;  4JBC A;  4R0T A;  2I6P A;  4YR8 B;  2QBS A;  1T49 A;  2X5O A;  3LJ8 A;  4ICZ A;  3I80 A;  3S3H A;  3CM3 A;  2Y96 A;  4H1O A;  4HRF A;  1YTW A;  2QBP A;  3CWE A;  4HV4 A;  1BZJ A;  1PTV A;  2NT7 A;  3S4O A;  4ZRT A;  3ZM3 A;  1VHR A;  2PBN A;  3D42 A;  1I9T A;  4QAH A;  3EZZ A;  3BRH A;  3EB1 A;  3A5K A;  4OHH A;  5MMZ B;  2GP0 A;  2VEV A;  3M4U A;  4H34 A;  1OEV A;  4Y14 A;  4RI4 A;  2I5X A;  5KAA A;  2G6Z A;  1ZCK A;  2YDU A;  4KI9 A;  1YN9 A;  2XPC A;  1U24 A;  5BUG A;  1L8G A;  3QCM A;  2I42 A;  3O5X A;  1JF7 A;  3OLR A;  5J8R A;  2CM2 A;  4R30 A;  3ZM1 A;  4RI5 A;  2P4D A;  1Q6P A;  2B3O A;  2CNG A;  2HNP A;  3SR9 A;  1G7G A;  5KA2 A;  1I57 A;  3QCJ A;  1Q6N A;  2I3U A;  1OHD A;  5K23 A;  4NWF A;  3S3F A;  3ZM0 A;  4PVG A;  3B7O A;  3QCD A;  1YZ4 A;  1EEO A;  2CM3 A;  1PXH A;  2RF6 A;  2F6Y A;  3ZMQ A;  3MVN A;  3V0G A;  1Q6M A;  4ZI4 A;  2OUD A;  1G1G A;  2UAG A;  4OHE A;  3ZM5 A;  5GTJ A;  4JMJ A;  2H4G A;  2XJA A;  3F9B A;  4RHG A;  3GXG A;  1YWF A;  1LYV A;  3S4E A;  4BJO A;  2CMA A;  4RH9 A;  3F41 A;  3OMH A;  3EU0 A;  2HNQ A;  2VEY A;  2FH7 A;  2GC6 A;  3F9A A;  4NND A;  2WTZ A;  1J6U A;  1L8K A;  1FGS A;  3NME A;  2B4O A;  2PQ5 A;  1OHC A;  2A8B A;  5K25 A;  2I75 A;  2F6F A;  1C87 A;  1ONY A;  4RH5 A;  2OOQ A;  3QCB A;  2WGP A;  2Y2F A;  2QEP A;  3QCE A;  1XXV A;  2F6W A;  1OEM X;  5KA7 A;  1PA9 A;  1WRM A;  1GWZ A;  1ZCL A;  1SUG A;  3O4S A;  4KYQ A;  2F00 A;  3N2A A;  2QCT A;  2QDP A;  1MKP A;  2BZL A;  4D3P A;  1KAV A;  2GC5 A;  3O3L A;  2H4V A;  5KA1 A;  2J17 A;  2CNH A;  4R0S A;  1R6H A;  4WOH A;  2B4S A;  4MBB A;  1I9S A;  4IKC A;  2F70 A;  5M43 A;  3D1O A;  1AAX A;  4YAA A;  1EEH A;  4JMK A;  3RGO A;  4GE5 A;  1V3A A;  1GQY A;  3F81 A;  2Q47 A;  1C83 A;  1A5Y A;  1G1F A;  1X24 A;  3V0J A;  1JBW A;  1PTT A;  4J51 A;  1YTS A;  2J16 B;  3O4U A;  4GRY A;  2I6O A;  2PT0 A;  4GE2 A;  4GFV A;  1UAG A;  3V0F A;  3BLU A;  4GRZ A;  4UAG A;  5IBS A;  2B4U A;  1C86 A;  3AWE A;  5A5F A;  4HJQ A;  2DXP A;  4QUM A;  4I8N A;  3PYZ A;  1O5Z A;  2UUP A;  4OHI A; 
#chains in the Genus database with same CATH homology
 2OC3 A;  1PH0 A;  2H02 A;  4KYR A;  1FPZ A;  5K22 A;  1NO6 A;  4QBW A;  4ERC A;  2VEW A;  1WAX A;  4NX8 A;  4WU3 A;  1ONZ A;  1QZ0 A;  2CNE A;  3QCG A;  1U25 A;  2HC1 A;  2HC2 A;  2I3R A;  1OEU A;  1Q1M A;  1U26 A;  1XRI A;  4QUN A;  3N0A A;  2CNF A;  2HY3 A;  3H2X A;  2C7S A;  2F6T A;  1T48 A;  1XBO A;  2CNI A;  2F46 A;  2F6V A;  1G4W R;  2BGD A;  3SME A;  1C84 A;  4JNB A;  2QCJ A;  5HDE A;  2G59 A;  1P15 A;  3QCF A;  1G1H A;  5IBM A;  2CFV A;  2HB1 A;  1FQ1 A;  1OHE A;  2ESB A;  3D44 A;  2CM7 A;  3A5J A;  2BGE A;  4GWF A;  2SHP A;  4D3R A;  1M3G A;  1OEO X;  1EEN A;  1J4X A;  2I6I A;  3EAX A;  4GFU A;  2GWO A;  2VEU A;  1NWL A;  1YGR A;  3AWG A;  2B4P A;  2I6M A;  4D3Q A;  2HXP A;  1ZZW A;  3I36 A;  1YGU A;  1RPM A;  2M3V A;  5BX1 A;  1NWE A;  2PI7 A;  1BZC A;  5I6V A;  1Q6S A;  1LAR A;  4Y2E A;  5LXQ B;  1XXP A;  1Q6J A;  2NTA A;  5K9V A;  1PYN A;  4GS0 A;  4WTY A;  3MOZ A;  2A3K A;  3MOW A;  5KAB A;  3QCK A;  4QAP A;  2QBR A;  3QCI A;  4RKK A;  2MBC A;  3S3E A;  1OES A;  2AHS A;  1G4U S;  4NWG A;  1C85 A;  2AZR A;  3U96 A;  2F71 A;  2R0B A;  1QXK A;  5AWX A;  5KA8 A;  5KA4 A;  5KAD A;  1JLN A;  1BZH A;  2H03 A;  1NL9 A;  3MMJ A;  2NLK A;  3I7Z A;  2B07 A;  2QDM A;  3S3K A;  3RO1 A;  4B04 A;  2VEX A;  2HCM A;  2I6J A;  1WCH A;  1PA1 A;  3D1Q A;  1YPT A;  4BPC A;  2NZ6 A;  2ZN7 A;  3GXH A;  2BV5 A;  3ZV2 A;  3BM8 A;  2IMG A;  3ZMP A;  2Q05 A;  4QBE A;  5KA0 A;  2BIJ A;  1YTN A;  2HVL A;  5K24 A;  2OZ5 A;  4OHD A;  4DGP A;  2FJN A;  4NYH A;  3F99 A;  5EHP A;  2CMB A;  5BZX A;  3V0H A;  2I4G A;  1PTY A;  2FJM A;  2PSZ A;  4OHL A;  2PA5 A;  5KA9 A;  2JJD A;  2I4E A;  2B49 A;  1NNY A;  2GJT A;  1RXD A;  3RZ2 A;  2ZMM A;  1T4J A;  1GFY A;  2QBQ A;  2I1Y A;  2E0T A;  4GE6 A;  4WU2 A;  5BZZ A;  2F6Z A;  2NT2 A;  3PS5 A;  2NV5 A;  4Z6B A;  3QCC A;  1PTU A;  3O4T A;  2CM8 A;  1OET A;  3QKQ A;  3V0D A;  2CJZ A;  3V0E A;  1KAK A;  5KA3 A;  5EHR A;  2I4H A;  3QCN A;  4AZ1 A;  3RGQ A;  3BLT A;  4TVV A;  1NZ7 A;  1YFO A;  1Q6T A;  5K9W A;  3QKP A;  4DGX A;  2QDC A;  3AWF A;  2H04 A;  1ECV A;  5KAC A;  2CMC A;  3D1H A;  3D9C A;  4RDD A;  1LQF A;  4ZN5 A;  1C88 A;  2P6X A;  1FPR A;  3QCH A;  2J16 A;  3ZM2 A;  3EMU A;  3QCL A;  1XM2 A;  4HJP A;  1ZC0 A;  2C46 A;  2H4K A;  4S0G A;  1D5R A;  3V0I A;  4PYH A;  1G7F A;  4JBC A;  4R0T A;  2I6P A;  4YR8 B;  2QBS A;  1T49 A;  3LJ8 A;  4ICZ A;  3I80 A;  3S3H A;  3CM3 A;  2Y96 A;  4H1O A;  4HRF A;  1YTW A;  2QBP A;  3CWE A;  1BZJ A;  1PTV A;  2NT7 A;  3S4O A;  4ZRT A;  3ZM3 A;  1VHR A;  2PBN A;  3D42 A;  1I9T A;  4QAH A;  3EZZ A;  3BRH A;  3EB1 A;  3A5K A;  4OHH A;  5MMZ B;  2GP0 A;  2VEV A;  3M4U A;  4H34 A;  1OEV A;  4Y14 A;  4RI4 A;  2I5X A;  5KAA A;  2G6Z A;  1ZCK A;  2YDU A;  4KI9 A;  1YN9 A;  1U24 A;  5BUG A;  1L8G A;  3QCM A;  2I42 A;  3O5X A;  1JF7 A;  3OLR A;  5J8R A;  2CM2 A;  4R30 A;  3ZM1 A;  4RI5 A;  2P4D A;  1Q6P A;  2B3O A;  2CNG A;  2HNP A;  3SR9 A;  1G7G A;  5KA2 A;  1I57 A;  3QCJ A;  1Q6N A;  2I3U A;  1OHD A;  5K23 A;  4NWF A;  3S3F A;  3ZM0 A;  4PVG A;  3B7O A;  3QCD A;  1YZ4 A;  1EEO A;  2CM3 A;  1PXH A;  2RF6 A;  2F6Y A;  3ZMQ A;  3V0G A;  1Q6M A;  4ZI4 A;  2OUD A;  1G1G A;  4OHE A;  5GTJ A;  4JMJ A;  2H4G A;  3F9B A;  4RHG A;  3GXG A;  1YWF A;  1LYV A;  3S4E A;  4BJO A;  2CMA A;  4RH9 A;  3F41 A;  3OMH A;  3EU0 A;  2HNQ A;  2VEY A;  2FH7 A;  3F9A A;  4NND A;  1L8K A;  3NME A;  2B4O A;  2PQ5 A;  1OHC A;  2A8B A;  5K25 A;  2I75 A;  2F6F A;  1C87 A;  1ONY A;  4RH5 A;  2OOQ A;  3QCB A;  2WGP A;  2Y2F A;  2QEP A;  3QCE A;  1XXV A;  2F6W A;  1OEM X;  5KA7 A;  1PA9 A;  1WRM A;  1GWZ A;  1ZCL A;  1SUG A;  3O4S A;  4KYQ A;  2QCT A;  2QDP A;  1MKP A;  2BZL A;  4D3P A;  1KAV A;  3O3L A;  2H4V A;  5KA1 A;  2J17 A;  2CNH A;  4R0S A;  1R6H A;  4WOH A;  2B4S A;  4MBB A;  1I9S A;  4IKC A;  2F70 A;  5M43 A;  3D1O A;  1AAX A;  4YAA A;  4JMK A;  3RGO A;  4GE5 A;  1V3A A;  3F81 A;  2Q47 A;  1C83 A;  1A5Y A;  1G1F A;  1X24 A;  3V0J A;  1PTT A;  4J51 A;  1YTS A;  2J16 B;  3O4U A;  4GRY A;  2I6O A;  4GE2 A;  4GFV A;  3V0F A;  3BLU A;  4GRZ A;  5IBS A;  2B4U A;  1C86 A;  3AWE A;  4HJQ A;  2DXP A;  4QUM A;  4I8N A;  2PT0 A;  4OHI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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