1PU8A

Crystal structure of h.pylori 3-methyladenine dna glycosylase (magiii) bound to 1,n6-ethenoadenine
Total Genus 85
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
85
sequence length
215
structure length
214
Chain Sequence
LDSFEILKALKSLDLLKNAPAWWWPNALKFEALLGAVLTQNTKFEAVLKSLENLKNAFILENDDEINLKKIAYIEFSKLAECVRPSGFYNQKAKRLIDLSGNILKDFQSFENFKQEVTREWLLDQKGIGKESADAILCYACAKEVMVVDKYSYLFLKKLGIEIEDYDELQHFFEKGVQENLNSALALYENTISLAQLYARFHGIVEFSKQKLEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of 3-methyladenine DNA glycosylase MagIII and the recognition of alkylated bases
pubmed doi rcsb
molecule keywords 3-METHYLADENINE DNA GLYCOSYLASE
molecule tags Hydrolase
source organism Helicobacter pylori
total genus 85
structure length 214
sequence length 215
chains with identical sequence B
ec nomenclature
pdb deposition date 2003-06-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00633 HHH Helix-hairpin-helix motif
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1pu8A02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1pu8A01
1KG3A 3I0XA 3CWSA 1KG2A 1RRQA 3IHOA 1RRSA 1NKUA 4OFHA 4AIAA 2NOBA 3I0WA 1YQKA 3OH6A 1WEFA 2NOEA 2NOIA 4EJZA 1ORNA 1HU0A 1XG7A 1LWYA 1NGNA 3N5NX 4OFEA 1KG7A 3OGDA 1MPGA 4EW4A 1YQLA 2JHNA 4DK9A 1KG4A 5DPKA 4EW0A 2ABKA 1KG6A 3D4VA 4EA5A 2XHIA 1M3QA 1LWVA 1P59A 1MUNA 4OFAA 1N39A 3CVTA 1FN7A 3FHGA 2I5WA 1LWWA 1PU6A 4B23A 4YOQA 1KQJA 2YG8A 1N3CA 3CW7A 2JG6A 1KG5A 1MUDA 2NOZA 2OFIA 1YQRA 4EA4A 3CWUA 1PVSA 3CWTA 1M3HA 1PU7A 3CVSA 3CWAA 1MUYA 4HSBA 1P7MA 1KO9A 1WEGA 4YPHA 4B21A 5CHZA 2H56A 4PIIA 4EVVA 2YG9A 1VRLA 4UNFA 3KNTA 2NOFA 1YQMA 4AI5A 3F0ZA 1N3AA 4AI4A 4E9HA 2NOLA 5KN9A 1LMZA 3OH9A 1PU8A 5KN8A 3FHFA 3N0UA 4E9GA 4YPRA 2OFKA 4E9FA 4EJYA 3G0QA 4B22A 1XQPA 1EBMA 1KEAA 2JHJA 3KTUA 4UOBA 1ORPA 3FSPA 4E9EA 5AN4A 3IH7A 3F10A 2NOHA 1WEIA 4B24A 1DIZA 3S6IA 1XQOA
chains in the Genus database with same CATH superfamily
1KG3A 3I0XA 3CWSA 1KG2A 3L2WA 4E7KA 1RRQA 3IHOA 4BE1A 1RRSA 1NKUA 4OFHA 4AIAA 2NOBA 3S3MA 3OY9A 3I0WA 1YQKA 3OH6A 2V75A 1WEFA 3L2UA 4ZTJA 2NOEA 2NOIA 4E7HA 4EJZA 4E7IA 1ORNA 1HU0A 1XG7A 3S3NA 1LWYA 1NGNA 3N5NX 4BE2A 4OFEA 1KG7A 3OGDA 1MPGA 4EW4A 1YQLA 2JHNA 4DK9A 1KG4A 3OYFA 5DPKA 5FRNA 4EW0A 2ABKA 3OYDA 1KG6A 3D4VA 4EA5A 3LCNA 2XHIA 3OYKA 1M3QA 1P59A 1LWVA 1MUNA 4OFAA 1N39A 3CVTA 1FN7A 3FHGA 3OYEA 3L2RA 2I5WA 1LWWA 1PU6A 4B23A 4YOQA 1KQJA 2YG8A 1N3CA 3CW7A 2JG6A 2JPSA 1KG5A 1MUDA 2NOZA 2OFIA 1YQRA 3OYCA 4EA4A 3CWUA 1PVSA 3OYMA 4BDYA 3CWTA 4NZGA 1M3HA 4BE0A 4BDZA 1PU7A 3CVSA 3CWAA 1MUYA 4HSBA 4E7LA 1P7MA 1KO9A 1WEGA 4YPHA 3VW4A 5FRMA 3OYBA 4B21A 5CHZA 3OYIA 2W03A 2H56A 3OYGA 4PIIA 4EVVA 2YG9A 1VRLA 4UNFA 3KNTA 3R2XC 1YQMA 2NOFA 4AI5A 3F0ZA 1N3AA 4AI4A 3OS0A 5FROA 3OYJA 4E9HA 3OYAA 5KN9A 1LMZA 2NOLA 3OH9A 1PU8A 3OYHA 4E7JA 5KN8A 3FHFA 3OYLA 3N0UA 4BACA 4E9GA 1U84A 4YPRA 2OFKA 4E9FA 4EJYA 3L2QA 3G0QA 4B22A 3OS1A 1XQPA 1EBMA 1KEAA 2JHJA 3KTUA 4UOBA 1ORPA 4ZTFA 3FSPA 4E9EA 5AN4A 3L2VA 3IH7A 3OS2A 3F10A 2NOHA 3NNQA 2W04A 1WEIA 3S3OA 3OYNA 4B24A 1DIZA 4IKFA 3S6IA 1XQOA
chains in the Genus database with same CATH topology
1KG3A 3I0XA 3CWSA 1KG2A 1RRQA 3IHOA 1RRSA 1NKUA 4OFHA 4AIAA 2NOBA 3I0WA 1YQKA 3OH6A 1WEFA 2NOEA 2NOIA 4EJZA 1ORNA 1HU0A 1XG7A 1LWYA 1NGNA 3N5NX 4OFEA 1KG7A 3OGDA 1MPGA 4EW4A 1YQLA 2JHNA 4DK9A 1KG4A 5DPKA 4EW0A 2ABKA 1KG6A 3D4VA 4EA5A 2XHIA 1M3QA 1LWVA 1P59A 1MUNA 4OFAA 1N39A 3CVTA 1FN7A 3FHGA 2I5WA 1LWWA 1PU6A 4B23A 4YOQA 1KQJA 2YG8A 1N3CA 3CW7A 2JG6A 1KG5A 1MUDA 2NOZA 2OFIA 1YQRA 4EA4A 3CWUA 1PVSA 3CWTA 1M3HA 1PU7A 3CVSA 3CWAA 1MUYA 4HSBA 1P7MA 1KO9A 1WEGA 4YPHA 4B21A 5CHZA 2H56A 4PIIA 4EVVA 2YG9A 1VRLA 4UNFA 3KNTA 2NOFA 1YQMA 4AI5A 3F0ZA 1N3AA 4AI4A 4E9HA 2NOLA 5KN9A 1LMZA 3OH9A 1PU8A 5KN8A 3FHFA 3N0UA 4E9GA 4YPRA 2OFKA 4E9FA 4EJYA 3G0QA 4B22A 1XQPA 1EBMA 1KEAA 2JHJA 3KTUA 4UOBA 1ORPA 3FSPA 4E9EA 5AN4A 3IH7A 3F10A 2NOHA 1WEIA 4B24A 1DIZA 3S6IA 1XQOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KG3 A;  3I0X A;  3CWS A;  1KG2 A;  1RRQ A;  3IHO A;  1RRS A;  1NKU A;  4OFH A;  4AIA A;  2NOB A;  3I0W A;  1YQK A;  3OH6 A;  1WEF A;  2NOE A;  2NOI A;  4EJZ A;  1ORN A;  1HU0 A;  1XG7 A;  1LWY A;  1NGN A;  3N5N X;  4OFE A;  1KG7 A;  3OGD A;  1MPG A;  4EW4 A;  1YQL A;  2JHN A;  4DK9 A;  1KG4 A;  5DPK A;  4EW0 A;  2ABK A;  1KG6 A;  3D4V A;  4EA5 A;  2XHI A;  1M3Q A;  1LWV A;  1P59 A;  1MUN A;  4OFA A;  1N39 A;  3CVT A;  1FN7 A;  3FHG A;  2I5W A;  1LWW A;  1PU6 A;  4B23 A;  4YOQ A;  1KQJ A;  2YG8 A;  1N3C A;  3CW7 A;  2JG6 A;  1KG5 A;  1MUD A;  2NOZ A;  2OFI A;  1YQR A;  4EA4 A;  3CWU A;  1PVS A;  3CWT A;  1M3H A;  1PU7 A;  3CVS A;  3CWA A;  1MUY A;  4HSB A;  1P7M A;  1KO9 A;  1WEG A;  4YPH A;  4B21 A;  5CHZ A;  2H56 A;  4PII A;  4EVV A;  2YG9 A;  1VRL A;  4UNF A;  3KNT A;  2NOF A;  1YQM A;  4AI5 A;  3F0Z A;  1N3A A;  4AI4 A;  4E9H A;  2NOL A;  5KN9 A;  1LMZ A;  3OH9 A;  1PU8 A;  5KN8 A;  3FHF A;  3N0U A;  4E9G A;  4YPR A;  2OFK A;  4E9F A;  4EJY A;  3G0Q A;  4B22 A;  1XQP A;  1EBM A;  1KEA A;  2JHJ A;  3KTU A;  4UOB A;  1ORP A;  3FSP A;  4E9E A;  5AN4 A;  3IH7 A;  3F10 A;  2NOH A;  1WEI A;  4B24 A;  1DIZ A;  3S6I A;  1XQO A; 
#chains in the Genus database with same CATH topology
 1KG3 A;  3I0X A;  3CWS A;  1KG2 A;  3L2W A;  4E7K A;  1RRQ A;  3IHO A;  4BE1 A;  1RRS A;  1NKU A;  4OFH A;  4AIA A;  2NOB A;  3S3M A;  3OY9 A;  3I0W A;  1YQK A;  3OH6 A;  2V75 A;  1WEF A;  3L2U A;  4ZTJ A;  2NOE A;  2NOI A;  4E7H A;  4EJZ A;  4E7I A;  1ORN A;  1HU0 A;  1XG7 A;  3S3N A;  1LWY A;  1NGN A;  3N5N X;  4BE2 A;  4OFE A;  1KG7 A;  3OGD A;  1MPG A;  4EW4 A;  1YQL A;  2JHN A;  4DK9 A;  1KG4 A;  3OYF A;  5DPK A;  5FRN A;  4EW0 A;  2ABK A;  3OYD A;  1KG6 A;  3D4V A;  4EA5 A;  3LCN A;  2XHI A;  3OYK A;  1M3Q A;  1P59 A;  1LWV A;  1MUN A;  4OFA A;  1N39 A;  3CVT A;  1FN7 A;  3FHG A;  3OYE A;  3L2R A;  2I5W A;  1LWW A;  1PU6 A;  4B23 A;  4YOQ A;  1KQJ A;  2YG8 A;  1N3C A;  3CW7 A;  2JG6 A;  2JPS A;  1KG5 A;  1MUD A;  2NOZ A;  2OFI A;  1YQR A;  3OYC A;  4EA4 A;  3CWU A;  1PVS A;  3OYM A;  4BDY A;  3CWT A;  4NZG A;  1M3H A;  4BE0 A;  4BDZ A;  1PU7 A;  3CVS A;  3CWA A;  1MUY A;  4HSB A;  4E7L A;  1P7M A;  1KO9 A;  1WEG A;  4YPH A;  3VW4 A;  5FRM A;  3OYB A;  4B21 A;  5CHZ A;  3OYI A;  2W03 A;  2H56 A;  3OYG A;  4PII A;  4EVV A;  2YG9 A;  1VRL A;  4UNF A;  3KNT A;  3R2X C;  1YQM A;  2NOF A;  4AI5 A;  3F0Z A;  1N3A A;  4AI4 A;  3OS0 A;  5FRO A;  3OYJ A;  4E9H A;  3OYA A;  5KN9 A;  1LMZ A;  2NOL A;  3OH9 A;  1PU8 A;  3OYH A;  4E7J A;  5KN8 A;  3FHF A;  3OYL A;  3N0U A;  4BAC A;  4E9G A;  1U84 A;  4YPR A;  2OFK A;  4E9F A;  4EJY A;  3L2Q A;  3G0Q A;  4B22 A;  3OS1 A;  1XQP A;  1EBM A;  1KEA A;  2JHJ A;  3KTU A;  4UOB A;  1ORP A;  4ZTF A;  3FSP A;  4E9E A;  5AN4 A;  3L2V A;  3IH7 A;  3OS2 A;  3F10 A;  2NOH A;  3NNQ A;  2W04 A;  1WEI A;  3S3O A;  3OYN A;  4B24 A;  1DIZ A;  4IKF A;  3S6I A;  1XQO A; 
#chains in the Genus database with same CATH homology
 1KG3 A;  3I0X A;  3CWS A;  1KG2 A;  1RRQ A;  3IHO A;  1RRS A;  1NKU A;  4OFH A;  4AIA A;  2NOB A;  3I0W A;  1YQK A;  3OH6 A;  1WEF A;  2NOE A;  2NOI A;  4EJZ A;  1ORN A;  1HU0 A;  1XG7 A;  1LWY A;  1NGN A;  3N5N X;  4OFE A;  1KG7 A;  3OGD A;  1MPG A;  4EW4 A;  1YQL A;  2JHN A;  4DK9 A;  1KG4 A;  5DPK A;  4EW0 A;  2ABK A;  1KG6 A;  3D4V A;  4EA5 A;  2XHI A;  1M3Q A;  1LWV A;  1P59 A;  1MUN A;  4OFA A;  1N39 A;  3CVT A;  1FN7 A;  3FHG A;  2I5W A;  1LWW A;  1PU6 A;  4B23 A;  4YOQ A;  1KQJ A;  2YG8 A;  1N3C A;  3CW7 A;  2JG6 A;  1KG5 A;  1MUD A;  2NOZ A;  2OFI A;  1YQR A;  4EA4 A;  3CWU A;  1PVS A;  3CWT A;  1M3H A;  1PU7 A;  3CVS A;  3CWA A;  1MUY A;  4HSB A;  1P7M A;  1KO9 A;  1WEG A;  4YPH A;  4B21 A;  5CHZ A;  2H56 A;  4PII A;  4EVV A;  2YG9 A;  1VRL A;  4UNF A;  3KNT A;  2NOF A;  1YQM A;  4AI5 A;  3F0Z A;  1N3A A;  4AI4 A;  4E9H A;  2NOL A;  5KN9 A;  1LMZ A;  3OH9 A;  1PU8 A;  5KN8 A;  3FHF A;  3N0U A;  4E9G A;  4YPR A;  2OFK A;  4E9F A;  4EJY A;  3G0Q A;  4B22 A;  1XQP A;  1EBM A;  1KEA A;  2JHJ A;  3KTU A;  4UOB A;  1ORP A;  3FSP A;  4E9E A;  5AN4 A;  3IH7 A;  3F10 A;  2NOH A;  1WEI A;  4B24 A;  1DIZ A;  3S6I A;  1XQO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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