1PU8A

Crystal structure of h.pylori 3-methyladenine dna glycosylase (magiii) bound to 1,n6-ethenoadenine
Total Genus 85
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
85
sequence length
215
structure length
214
Chain Sequence
LDSFEILKALKSLDLLKNAPAWWWPNALKFEALLGAVLTQNTKFEAVLKSLENLKNAFILENDDEINLKKIAYIEFSKLAECVRPSGFYNQKAKRLIDLSGNILKDFQSFENFKQEVTREWLLDQKGIGKESADAILCYACAKEVMVVDKYSYLFLKKLGIEIEDYDELQHFFEKGVQENLNSALALYENTISLAQLYARFHGIVEFSKQKLEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords 3-METHYLADENINE DNA GLYCOSYLASE
publication title Crystal structures of 3-methyladenine DNA glycosylase MagIII and the recognition of alkylated bases
pubmed doi rcsb
source organism Helicobacter pylori
molecule tags Hydrolase
total genus 85
structure length 214
sequence length 215
chains with identical sequence B
ec nomenclature
pdb deposition date 2003-06-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00633 HHH Helix-hairpin-helix motif
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1pu8A02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1pu8A01
4UOBA 4YOQA 1XQPA 3FHFA 1ORPA 5KN8A 2I5WA 3CWTA 1PU8A 2YG9A 2JHNA 3D4VA 4HSBA 3CWUA 3CVSA 5DPKA 4OFEA 1KG5A 1LWWA 2NOBA 1KG4A 1KG2A 4OFHA 1RRSA 2ABKA 1MUYA 4YPRA 1RRQA 4AI4A 1PU6A 4E9GA 2H56A 5CHZA 3IHOA 4B21A 4OFAA 1FN7A 1KEAA 2NOEA 2JHJA 1VRLA 1NGNA 1DIZA 3CW7A 3FSPA 1MUDA 4B24A 3N0UA 3CWAA 2NOLA 1KG7A 3I0XA 3OH9A 4B23A 2JG6A 4AI5A 4E9FA 4EA4A 1XG7A 1WEFA 4UNFA 1N39A 1YQRA 1N3AA 3KNTA 1NKUA 1LWYA 2YG8A 2NOFA 1KQJA 4YPHA 4E9HA 4EW4A 2NOZA 3OGDA 3I0WA 3FHGA 3F10A 4EVVA 4AIAA 4PIIA 1HU0A 5KN9A 3IH7A 3KTUA 3G0QA 3S6IA 1KG6A 1PVSA 1WEIA 3CVTA 4DK9A 1M3QA 2XHIA 4EJYA 2NOIA 1P59A 2OFKA 4EJZA 1XQOA 1EBMA 1WEGA 1YQMA 4E9EA 3CWSA 1YQKA 4EW0A 1N3CA 1P7MA 4B22A 3OH6A 1ORNA 1PU7A 3N5NX 1M3HA 4EA5A 1LWVA 1KG3A 2OFIA 1YQLA 1MPGA 1MUNA 1LMZA 3F0ZA 5AN4A 2NOHA 1KO9A
chains in the Genus database with same CATH superfamily
4UOBA 4YOQA 4BE0A 1XQPA 3FHFA 1ORPA 4ZTJA 5KN8A 2I5WA 3CWTA 2W04A 1PU8A 2YG9A 2JHNA 3L2RA 3D4VA 4HSBA 2JPSA 3OYCA 3CWUA 3CVSA 5DPKA 4OFEA 1KG5A 3S3NA 3OYLA 1LWWA 2NOBA 1KG4A 1KG2A 4OFHA 1RRSA 2ABKA 1MUYA 3OS0A 4YPRA 1RRQA 4AI4A 1PU6A 4E9GA 3OS2A 3OYFA 2H56A 5CHZA 3IHOA 3OYNA 3OYJA 4B21A 4OFAA 1FN7A 1KEAA 2NOEA 2JHJA 4BACA 1VRLA 1NGNA 1DIZA 3CW7A 3FSPA 1MUDA 4B24A 3N0UA 3CWAA 2NOLA 4BE1A 1KG7A 3I0XA 3OH9A 4B23A 2JG6A 3OYBA 4AI5A 4E7KA 3R2XC 3S3OA 4E9FA 4EA4A 1XG7A 4ZTFA 1WEFA 3OS1A 4UNFA 4E7IA 3L2QA 1N39A 3OYKA 1YQRA 1N3AA 3OYHA 3KNTA 1NKUA 1LWYA 2YG8A 2V75A 3OY9A 2NOFA 1KQJA 4YPHA 4E7HA 4E9HA 4EW4A 3OGDA 3I0WA 3FHGA 3F10A 4E7JA 2NOZA 4BDYA 4EVVA 4AIAA 4PIIA 1HU0A 4IKFA 5KN9A 3VW4A 3NNQA 3IH7A 3KTUA 3G0QA 4E7LA 3S6IA 1KG6A 1PVSA 1WEIA 4NZGA 3CVTA 5FRNA 4DK9A 1M3QA 2XHIA 4EJYA 2NOIA 3OYGA 3L2WA 1P59A 2OFKA 4EJZA 1XQOA 3S3MA 1EBMA 3LCNA 1WEGA 1YQMA 4E9EA 3CWSA 1YQKA 4BE2A 3OYMA 2W03A 4BDZA 4EW0A 3L2UA 1N3CA 1P7MA 3L2VA 3OYDA 4B22A 3OYAA 3OH6A 5FROA 1ORNA 1PU7A 3N5NX 1M3HA 4EA5A 1LWVA 1KG3A 2OFIA 5FRMA 1YQLA 1MPGA 1MUNA 3OYIA 1LMZA 3F0ZA 5AN4A 1U84A 3OYEA 2NOHA 1KO9A
chains in the Genus database with same CATH topology
4UOBA 4YOQA 1XQPA 3FHFA 1ORPA 5KN8A 2I5WA 3CWTA 1PU8A 2YG9A 2JHNA 3D4VA 4HSBA 3CWUA 3CVSA 5DPKA 4OFEA 1KG5A 1LWWA 2NOBA 1KG4A 1KG2A 4OFHA 1RRSA 2ABKA 1MUYA 4YPRA 1RRQA 4AI4A 1PU6A 4E9GA 2H56A 5CHZA 3IHOA 4B21A 4OFAA 1FN7A 1KEAA 2NOEA 2JHJA 1VRLA 1NGNA 1DIZA 3CW7A 3FSPA 1MUDA 4B24A 3N0UA 3CWAA 2NOLA 1KG7A 3I0XA 3OH9A 4B23A 2JG6A 4AI5A 4E9FA 4EA4A 1XG7A 1WEFA 4UNFA 1N39A 1YQRA 1N3AA 3KNTA 1NKUA 1LWYA 2YG8A 2NOFA 1KQJA 4YPHA 4E9HA 4EW4A 2NOZA 3OGDA 3I0WA 3FHGA 3F10A 4EVVA 4AIAA 4PIIA 1HU0A 5KN9A 3IH7A 3KTUA 3G0QA 3S6IA 1KG6A 1PVSA 1WEIA 3CVTA 4DK9A 1M3QA 2XHIA 4EJYA 2NOIA 1P59A 2OFKA 4EJZA 1XQOA 1EBMA 1WEGA 1YQMA 4E9EA 3CWSA 1YQKA 4EW0A 1N3CA 1P7MA 4B22A 3OH6A 1ORNA 1PU7A 3N5NX 1M3HA 4EA5A 1LWVA 1KG3A 2OFIA 1YQLA 1MPGA 1MUNA 1LMZA 3F0ZA 5AN4A 2NOHA 1KO9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4UOB A;  4YOQ A;  1XQP A;  3FHF A;  1ORP A;  5KN8 A;  2I5W A;  3CWT A;  1PU8 A;  2YG9 A;  2JHN A;  3D4V A;  4HSB A;  3CWU A;  3CVS A;  5DPK A;  4OFE A;  1KG5 A;  1LWW A;  2NOB A;  1KG4 A;  1KG2 A;  4OFH A;  1RRS A;  2ABK A;  1MUY A;  4YPR A;  1RRQ A;  4AI4 A;  1PU6 A;  4E9G A;  2H56 A;  5CHZ A;  3IHO A;  4B21 A;  4OFA A;  1FN7 A;  1KEA A;  2NOE A;  2JHJ A;  1VRL A;  1NGN A;  1DIZ A;  3CW7 A;  3FSP A;  1MUD A;  4B24 A;  3N0U A;  3CWA A;  2NOL A;  1KG7 A;  3I0X A;  3OH9 A;  4B23 A;  2JG6 A;  4AI5 A;  4E9F A;  4EA4 A;  1XG7 A;  1WEF A;  4UNF A;  1N39 A;  1YQR A;  1N3A A;  3KNT A;  1NKU A;  1LWY A;  2YG8 A;  2NOF A;  1KQJ A;  4YPH A;  4E9H A;  4EW4 A;  2NOZ A;  3OGD A;  3I0W A;  3FHG A;  3F10 A;  4EVV A;  4AIA A;  4PII A;  1HU0 A;  5KN9 A;  3IH7 A;  3KTU A;  3G0Q A;  3S6I A;  1KG6 A;  1PVS A;  1WEI A;  3CVT A;  4DK9 A;  1M3Q A;  2XHI A;  4EJY A;  2NOI A;  1P59 A;  2OFK A;  4EJZ A;  1XQO A;  1EBM A;  1WEG A;  1YQM A;  4E9E A;  3CWS A;  1YQK A;  4EW0 A;  1N3C A;  1P7M A;  4B22 A;  3OH6 A;  1ORN A;  1PU7 A;  3N5N X;  1M3H A;  4EA5 A;  1LWV A;  1KG3 A;  2OFI A;  1YQL A;  1MPG A;  1MUN A;  1LMZ A;  3F0Z A;  5AN4 A;  2NOH A;  1KO9 A; 
#chains in the Genus database with same CATH topology
 4UOB A;  4YOQ A;  4BE0 A;  1XQP A;  3FHF A;  1ORP A;  4ZTJ A;  5KN8 A;  2I5W A;  3CWT A;  2W04 A;  1PU8 A;  2YG9 A;  2JHN A;  3L2R A;  3D4V A;  4HSB A;  2JPS A;  3OYC A;  3CWU A;  3CVS A;  5DPK A;  4OFE A;  1KG5 A;  3S3N A;  3OYL A;  1LWW A;  2NOB A;  1KG4 A;  1KG2 A;  4OFH A;  1RRS A;  2ABK A;  1MUY A;  3OS0 A;  4YPR A;  1RRQ A;  4AI4 A;  1PU6 A;  4E9G A;  3OS2 A;  3OYF A;  2H56 A;  5CHZ A;  3IHO A;  3OYN A;  3OYJ A;  4B21 A;  4OFA A;  1FN7 A;  1KEA A;  2NOE A;  2JHJ A;  4BAC A;  1VRL A;  1NGN A;  1DIZ A;  3CW7 A;  3FSP A;  1MUD A;  4B24 A;  3N0U A;  3CWA A;  2NOL A;  4BE1 A;  1KG7 A;  3I0X A;  3OH9 A;  4B23 A;  2JG6 A;  3OYB A;  4AI5 A;  4E7K A;  3R2X C;  3S3O A;  4E9F A;  4EA4 A;  1XG7 A;  4ZTF A;  1WEF A;  3OS1 A;  4UNF A;  4E7I A;  3L2Q A;  1N39 A;  3OYK A;  1YQR A;  1N3A A;  3OYH A;  3KNT A;  1NKU A;  1LWY A;  2YG8 A;  2V75 A;  3OY9 A;  2NOF A;  1KQJ A;  4YPH A;  4E7H A;  4E9H A;  4EW4 A;  3OGD A;  3I0W A;  3FHG A;  3F10 A;  4E7J A;  2NOZ A;  4BDY A;  4EVV A;  4AIA A;  4PII A;  1HU0 A;  4IKF A;  5KN9 A;  3VW4 A;  3NNQ A;  3IH7 A;  3KTU A;  3G0Q A;  4E7L A;  3S6I A;  1KG6 A;  1PVS A;  1WEI A;  4NZG A;  3CVT A;  5FRN A;  4DK9 A;  1M3Q A;  2XHI A;  4EJY A;  2NOI A;  3OYG A;  3L2W A;  1P59 A;  2OFK A;  4EJZ A;  1XQO A;  3S3M A;  1EBM A;  3LCN A;  1WEG A;  1YQM A;  4E9E A;  3CWS A;  1YQK A;  4BE2 A;  3OYM A;  2W03 A;  4BDZ A;  4EW0 A;  3L2U A;  1N3C A;  1P7M A;  3L2V A;  3OYD A;  4B22 A;  3OYA A;  3OH6 A;  5FRO A;  1ORN A;  1PU7 A;  3N5N X;  1M3H A;  4EA5 A;  1LWV A;  1KG3 A;  2OFI A;  5FRM A;  1YQL A;  1MPG A;  1MUN A;  3OYI A;  1LMZ A;  3F0Z A;  5AN4 A;  1U84 A;  3OYE A;  2NOH A;  1KO9 A; 
#chains in the Genus database with same CATH homology
 4UOB A;  4YOQ A;  1XQP A;  3FHF A;  1ORP A;  5KN8 A;  2I5W A;  3CWT A;  1PU8 A;  2YG9 A;  2JHN A;  3D4V A;  4HSB A;  3CWU A;  3CVS A;  5DPK A;  4OFE A;  1KG5 A;  1LWW A;  2NOB A;  1KG4 A;  1KG2 A;  4OFH A;  1RRS A;  2ABK A;  1MUY A;  4YPR A;  1RRQ A;  4AI4 A;  1PU6 A;  4E9G A;  2H56 A;  5CHZ A;  3IHO A;  4B21 A;  4OFA A;  1FN7 A;  1KEA A;  2NOE A;  2JHJ A;  1VRL A;  1NGN A;  1DIZ A;  3CW7 A;  3FSP A;  1MUD A;  4B24 A;  3N0U A;  3CWA A;  2NOL A;  1KG7 A;  3I0X A;  3OH9 A;  4B23 A;  2JG6 A;  4AI5 A;  4E9F A;  4EA4 A;  1XG7 A;  1WEF A;  4UNF A;  1N39 A;  1YQR A;  1N3A A;  3KNT A;  1NKU A;  1LWY A;  2YG8 A;  2NOF A;  1KQJ A;  4YPH A;  4E9H A;  4EW4 A;  2NOZ A;  3OGD A;  3I0W A;  3FHG A;  3F10 A;  4EVV A;  4AIA A;  4PII A;  1HU0 A;  5KN9 A;  3IH7 A;  3KTU A;  3G0Q A;  3S6I A;  1KG6 A;  1PVS A;  1WEI A;  3CVT A;  4DK9 A;  1M3Q A;  2XHI A;  4EJY A;  2NOI A;  1P59 A;  2OFK A;  4EJZ A;  1XQO A;  1EBM A;  1WEG A;  1YQM A;  4E9E A;  3CWS A;  1YQK A;  4EW0 A;  1N3C A;  1P7M A;  4B22 A;  3OH6 A;  1ORN A;  1PU7 A;  3N5N X;  1M3H A;  4EA5 A;  1LWV A;  1KG3 A;  2OFI A;  1YQL A;  1MPG A;  1MUN A;  1LMZ A;  3F0Z A;  5AN4 A;  2NOH A;  1KO9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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