1PVSA

3-methyladenine glcosylase ii(alka) hypoxanthine complex
Total Genus 89
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
89
sequence length
282
structure length
282
Chain Sequence
MYTLNWQPPYDWSWMLGFLAARAVSSVETVADSYYARSLAVGEYRGVVTAIPDIARHTLHINLSAGLEPVAAECLAKMSRLFDLQCNPQIVNGALGRLGAARPGLRLPGCVDAFEQGVRAILGQLVSVAMAAKLTARVAQLYGERLDDFPEYICFPTPQRLAAADPQALKALGMPLKRAEALIHLANAALEGTLPMTIPGDVEQAMKTLQTFPGIGRWTANYFALRGWQAKDVFLPDDYLIKQRFPGMTPAQIRRYAERWKPWRSYALLHIWYTEGWQPDEA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title 3-methyladenine-DNA glycosylase II: the crystal structure of an AlkA-hypoxanthine complex suggests the possibility of product inhibition.
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords DNA-3-methyladenine glycosylase II
total genus 89
structure length 282
sequence length 282
chains with identical sequence B
ec nomenclature ec 3.2.2.21: DNA-3-methyladenine glycosylase II.
pdb deposition date 2003-06-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
A PF06029 AlkA_N AlkA N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1pvsA02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1pvsA03
3.30.310.20 Alpha Beta 2-Layer Sandwich TATA-Binding Protein DNA-3-methyladenine glycosylase AlkA, N-terminal domain 1pvsA01
4E9GA 1KG6A 3KTUA 1ORPA 1KQJA 1RRSA 3CVTA 1LWWA 1N3AA 1LWVA 1KG3A 1FN7A 1YQRA 1ORNA 2ABKA 1M3HA 3I0WA 4OFEA 2I5WA 3CWTA 3CWAA 1HU0A 1RRQA 4B21A 3I0XA 3IH7A 1VRLA 1MUYA 4AI5A 1DIZA 2NOZA 3D4VA 1YQMA 3IHOA 4EW0A 4B23A 4YOQA 4AI4A 2H56A 1P59A 1N3CA 4EVVA 1WEGA 2OFKA 5CHZA 1KG2A 1NKUA 3N0UA 3CWUA 4DK9A 2NOLA 4EJYA 1PVSA 3CW7A 1YQKA 3CVSA 5KN9A 1LMZA 4E9EA 2NOBA 1XQPA 5DPKA 3FSPA 4PIIA 1PU6A 1NGNA 1WEFA 2OFIA 4E9HA 3CWSA 1PU7A 2JHNA 2NOHA 4OFAA 2YG8A 3F10A 1KO9A 1PU8A 4B24A 3G0QA 1N39A 2YG9A 4AIAA 4UOBA 1KG5A 1MUDA 2NOEA 3F0ZA 1MUNA 4EA5A 3N5NX 4B22A 1YQLA 1M3QA 4YPHA 3OH9A 2JG6A 1MPGA 1LWYA 3OGDA 1XQOA 4EJZA 4OFHA 2NOIA 4E9FA 3OH6A 4UNFA 1XG7A 3KNTA 1P7MA 1KG4A 1KG7A 3S6IA 1KEAA 5AN4A 4HSBA 4YPRA 4EA4A 3FHFA 2XHIA 4EW4A 1EBMA 5KN8A 2JHJA 3FHGA 2NOFA 1WEIA
chains in the Genus database with same CATH superfamily
3H1ZA 3KTUA 1KQJA 2MJ7A 1LWWA 1FN7A 4E7HA 3PDKA 2ZFDB 4OFEA 3ULXA 3CWTA 3OYNA 3CWAA 4B0AA 1MP9A 1NGMA 3UW2A 3BKQX 1YTBA 1J3MA 4ROCB 3OS0A 1QNAA 1R4XA 3T4NA 1YQMA 4WX8A 3N89A 4ROEB 3RPJA 4CFFA 1P59A 4QG5A 1VKLA 2V75A 2HL8A 5CHZA 1LXTA 2OOXA 1QNEA 1T6AA 2H5AX 3CVSA 5KN9A 1V5SA 2V8QA 2YH5A 1QN7A 1YTFA 4E7JA 2NOBA 5KL0A 4EALA 3RSMA 2JPIA 4E7KA 4OFAA 1KO9A 5JMVD 1N39A 1PCZA 1MUDA 2PWWA 4HJHA 1YQLA 1M3QA 2HL9A 2VJ0A 3OCIA 1XQOA 2W04A 4EAJA 3R2XC 3EAYA 3OLPA 4E9FA 2G30A 4UNFA 2FGTA 1KG4A 1PZDA 4PY5A 4HSBA 3OC3C 4EA4A 1EBMA 1C47A 3HS8A 2D0AA 3VW4A 3HS9A 1QTSA 1ORPA 5F9CA 1C9BB 5IYBP 1VOKA 2I5WA 5FROA 4NZGA 3DPUA 4WZSD 4BE0A 5FRMA 1KYFA 4AI5A 5IYDP 4EAIA 3LCNA 3IHOA 4EW0A 5BMNA 4B23A 4YOQA 1QN6A 5EPCA 3OSMA 4EVVA 2Y8QA 4ZTFA 3N0UA 1PCMX 4TPSA 1YQKA 2JPSA 4Q11A 1P5GX 4E9EA 3TDHA 4PIIA 1NGNA 1C4GA 2W03A 1P5DX 1PU7A 2QREA 2V9JA 2NOHA 3OYAA 4D7RA 3I3WA 2YG9A 4AIAA 1KG5A 4IKFA 2HZMA 3OYHA 3L2RA 2NOEA 2HKPA 2EHBD 3F0ZA 1EUVA 2NWVA 1KY6A 4YPHA 3OH9A 2JG6A 1LWYA 3OGDA 1QN9A 1VTOA 3OSTA 4OFHA 4BDZA 2NOIA 1KYDA 1VOLB 2D0BA 3OH6A 1XG7A 3S3OA 4D7QA 2FKFA 1KFIA 4BE2A 4EW4A 3FHGA 2NOFA 5IYCP 1AISA 4C7PA 3OYMA 1KG6A 1RRSA 3OYBA 3CVTA 1LWVA 1KG3A 1YQRA 1ORNA 2ABKA 2QR1A 3S3NA 2Z8UA 5FRNA 3DPTA 1NH2A 1JDYA 2O3OA 3VN5A 1VRLA 3ENCA 1DIZA 2NOZA 2H4LX 2IV8A 2FKMX 1TGHA 1N3CA 2H56A 4E7IA 2V92A 1WEGA 1B9KA 3KRMA 1KG2A 1NKUA 3SNSA 3CWUA 4EJYA 1U84A 3CW7A 1LMZA 1XQPA 1QN3A 3OYCA 5DPKA 3FSPA 3OYDA 1WEFA 4E9HA 2LAEA 1UT7A 2JHNA 2D0CA 1PU8A 3PMGA 3G0QA 4E7LA 4UOBA 4MRQA 3D7QA 3ENOC 2FUVA 2DKDA 1MUNA 4EA5A 3N5NX 4B22A 4EJZA 1M5Q1 1WQAA 4EAGA 5HSHA 2NVMA 4I8OA 1K35A 3S6IA 3OS2A 1KEAA 5AN4A 2HZSA 4BE1A 1NVPA 3FHFA 1KY7A 2XHIA 1UL7A 3L2UA 1UT4A 2QRDA 3OYLA 1E42A 4DULA 4E9GA 1QN8A 1RM1A 2IV9A 1K2YX 1N3AA 3L2QA 1M3HA 4IL8A 3I0WA 2JOIA 1CDWA 1HU0A 1RRQA 3TE5A 4B21A 3I0XA 3IH7A 1XSZA 2QLVA 1MUYA 2F7LA 3D4VA 3OYKA 3OSEA 3OS1A 4AI4A 2OFKA 2Y8LA 4DK9A 2NOLA 1PVSA 2R5XA 1TBPA 3OY9A 2NLVA 3OYEA 2MZ8A 2OOYA 1WJWA 5BMPA 3L2WA 4BACA 1Q9UA 2DKCA 3S3MA 5JN5A 4WXAA 4RODB 2DKAA 1PU6A 1KFQA 2OFIA 3CWSA 3NA5A 1D3UA 2YG8A 3F10A 1W80A 4ZTJA 4B24A 2Z0FA 1KYUA 3L2VA 1TUOA 4BDYA 1QN5A 1MPGA 3C04A 3EIKA 3OYGA 2QRCA 1QN4A 4BJUA 4EAKA 1QNCA 3NNQA 1TBAB 1QTPA 3KNTA 1P7MA 3OYFA 1PCJX 1JFIC 1KG7A 2YA3A 3OYJA 1QNBA 4YPRA 5KN8A 2JHJA 3OYIA 1WEIA 1VTLE 3ASMA
chains in the Genus database with same CATH topology
4E9GA 1KG6A 3KTUA 1ORPA 1KQJA 1RRSA 3CVTA 1LWWA 1N3AA 1LWVA 1KG3A 1FN7A 1YQRA 1ORNA 2ABKA 1M3HA 3I0WA 4OFEA 2I5WA 3CWTA 3CWAA 1HU0A 1RRQA 4B21A 3I0XA 3IH7A 1VRLA 1MUYA 4AI5A 1DIZA 2NOZA 3D4VA 1YQMA 3IHOA 4EW0A 4B23A 4YOQA 4AI4A 2H56A 1P59A 1N3CA 4EVVA 1WEGA 2OFKA 5CHZA 1KG2A 1NKUA 3N0UA 3CWUA 4DK9A 2NOLA 4EJYA 1PVSA 3CW7A 1YQKA 3CVSA 5KN9A 1LMZA 4E9EA 2NOBA 1XQPA 5DPKA 3FSPA 4PIIA 1PU6A 1NGNA 1WEFA 2OFIA 4E9HA 3CWSA 1PU7A 2JHNA 2NOHA 4OFAA 2YG8A 3F10A 1KO9A 1PU8A 4B24A 3G0QA 1N39A 2YG9A 4AIAA 4UOBA 1KG5A 1MUDA 2NOEA 3F0ZA 1MUNA 4EA5A 3N5NX 4B22A 1YQLA 1M3QA 4YPHA 3OH9A 2JG6A 1MPGA 1LWYA 3OGDA 1XQOA 4EJZA 4OFHA 2NOIA 4E9FA 3OH6A 4UNFA 1XG7A 3KNTA 1P7MA 1KG4A 1KG7A 3S6IA 1KEAA 5AN4A 4HSBA 4YPRA 4EA4A 3FHFA 2XHIA 4EW4A 1EBMA 5KN8A 2JHJA 3FHGA 2NOFA 1WEIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4E9G A;  1KG6 A;  3KTU A;  1ORP A;  1KQJ A;  1RRS A;  3CVT A;  1LWW A;  1N3A A;  1LWV A;  1KG3 A;  1FN7 A;  1YQR A;  1ORN A;  2ABK A;  1M3H A;  3I0W A;  4OFE A;  2I5W A;  3CWT A;  3CWA A;  1HU0 A;  1RRQ A;  4B21 A;  3I0X A;  3IH7 A;  1VRL A;  1MUY A;  4AI5 A;  1DIZ A;  2NOZ A;  3D4V A;  1YQM A;  3IHO A;  4EW0 A;  4B23 A;  4YOQ A;  4AI4 A;  2H56 A;  1P59 A;  1N3C A;  4EVV A;  1WEG A;  2OFK A;  5CHZ A;  1KG2 A;  1NKU A;  3N0U A;  3CWU A;  4DK9 A;  2NOL A;  4EJY A;  1PVS A;  3CW7 A;  1YQK A;  3CVS A;  5KN9 A;  1LMZ A;  4E9E A;  2NOB A;  1XQP A;  5DPK A;  3FSP A;  4PII A;  1PU6 A;  1NGN A;  1WEF A;  2OFI A;  4E9H A;  3CWS A;  1PU7 A;  2JHN A;  2NOH A;  4OFA A;  2YG8 A;  3F10 A;  1KO9 A;  1PU8 A;  4B24 A;  3G0Q A;  1N39 A;  2YG9 A;  4AIA A;  4UOB A;  1KG5 A;  1MUD A;  2NOE A;  3F0Z A;  1MUN A;  4EA5 A;  3N5N X;  4B22 A;  1YQL A;  1M3Q A;  4YPH A;  3OH9 A;  2JG6 A;  1MPG A;  1LWY A;  3OGD A;  1XQO A;  4EJZ A;  4OFH A;  2NOI A;  4E9F A;  3OH6 A;  4UNF A;  1XG7 A;  3KNT A;  1P7M A;  1KG4 A;  1KG7 A;  3S6I A;  1KEA A;  5AN4 A;  4HSB A;  4YPR A;  4EA4 A;  3FHF A;  2XHI A;  4EW4 A;  1EBM A;  5KN8 A;  2JHJ A;  3FHG A;  2NOF A;  1WEI A; 
#chains in the Genus database with same CATH topology
 3H1Z A;  3KTU A;  1KQJ A;  2MJ7 A;  1LWW A;  1FN7 A;  4E7H A;  3PDK A;  2ZFD B;  4OFE A;  3ULX A;  3CWT A;  3OYN A;  3CWA A;  4B0A A;  1MP9 A;  1NGM A;  3UW2 A;  3BKQ X;  1YTB A;  1J3M A;  4ROC B;  3OS0 A;  1QNA A;  1R4X A;  3T4N A;  1YQM A;  4WX8 A;  3N89 A;  4ROE B;  3RPJ A;  4CFF A;  1P59 A;  4QG5 A;  1VKL A;  2V75 A;  2HL8 A;  5CHZ A;  1LXT A;  2OOX A;  1QNE A;  1T6A A;  2H5A X;  3CVS A;  5KN9 A;  1V5S A;  2V8Q A;  2YH5 A;  1QN7 A;  1YTF A;  4E7J A;  2NOB A;  5KL0 A;  4EAL A;  3RSM A;  2JPI A;  4E7K A;  4OFA A;  1KO9 A;  5JMV D;  1N39 A;  1PCZ A;  1MUD A;  2PWW A;  4HJH A;  1YQL A;  1M3Q A;  2HL9 A;  2VJ0 A;  3OCI A;  1XQO A;  2W04 A;  4EAJ A;  3R2X C;  3EAY A;  3OLP A;  4E9F A;  2G30 A;  4UNF A;  2FGT A;  1KG4 A;  1PZD A;  4PY5 A;  4HSB A;  3OC3 C;  4EA4 A;  1EBM A;  1C47 A;  3HS8 A;  2D0A A;  3VW4 A;  3HS9 A;  1QTS A;  1ORP A;  5F9C A;  1C9B B;  5IYB P;  1VOK A;  2I5W A;  5FRO A;  4NZG A;  3DPU A;  4WZS D;  4BE0 A;  5FRM A;  1KYF A;  4AI5 A;  5IYD P;  4EAI A;  3LCN A;  3IHO A;  4EW0 A;  5BMN A;  4B23 A;  4YOQ A;  1QN6 A;  5EPC A;  3OSM A;  4EVV A;  2Y8Q A;  4ZTF A;  3N0U A;  1PCM X;  4TPS A;  1YQK A;  2JPS A;  4Q11 A;  1P5G X;  4E9E A;  3TDH A;  4PII A;  1NGN A;  1C4G A;  2W03 A;  1P5D X;  1PU7 A;  2QRE A;  2V9J A;  2NOH A;  3OYA A;  4D7R A;  3I3W A;  2YG9 A;  4AIA A;  1KG5 A;  4IKF A;  2HZM A;  3OYH A;  3L2R A;  2NOE A;  2HKP A;  2EHB D;  3F0Z A;  1EUV A;  2NWV A;  1KY6 A;  4YPH A;  3OH9 A;  2JG6 A;  1LWY A;  3OGD A;  1QN9 A;  1VTO A;  3OST A;  4OFH A;  4BDZ A;  2NOI A;  1KYD A;  1VOL B;  2D0B A;  3OH6 A;  1XG7 A;  3S3O A;  4D7Q A;  2FKF A;  1KFI A;  4BE2 A;  4EW4 A;  3FHG A;  2NOF A;  5IYC P;  1AIS A;  4C7P A;  3OYM A;  1KG6 A;  1RRS A;  3OYB A;  3CVT A;  1LWV A;  1KG3 A;  1YQR A;  1ORN A;  2ABK A;  2QR1 A;  3S3N A;  2Z8U A;  5FRN A;  3DPT A;  1NH2 A;  1JDY A;  2O3O A;  3VN5 A;  1VRL A;  3ENC A;  1DIZ A;  2NOZ A;  2H4L X;  2IV8 A;  2FKM X;  1TGH A;  1N3C A;  2H56 A;  4E7I A;  2V92 A;  1WEG A;  1B9K A;  3KRM A;  1KG2 A;  1NKU A;  3SNS A;  3CWU A;  4EJY A;  1U84 A;  3CW7 A;  1LMZ A;  1XQP A;  1QN3 A;  3OYC A;  5DPK A;  3FSP A;  3OYD A;  1WEF A;  4E9H A;  2LAE A;  1UT7 A;  2JHN A;  2D0C A;  1PU8 A;  3PMG A;  3G0Q A;  4E7L A;  4UOB A;  4MRQ A;  3D7Q A;  3ENO C;  2FUV A;  2DKD A;  1MUN A;  4EA5 A;  3N5N X;  4B22 A;  4EJZ A;  1M5Q 1;  1WQA A;  4EAG A;  5HSH A;  2NVM A;  4I8O A;  1K35 A;  3S6I A;  3OS2 A;  1KEA A;  5AN4 A;  2HZS A;  4BE1 A;  1NVP A;  3FHF A;  1KY7 A;  2XHI A;  1UL7 A;  3L2U A;  1UT4 A;  2QRD A;  3OYL A;  1E42 A;  4DUL A;  4E9G A;  1QN8 A;  1RM1 A;  2IV9 A;  1K2Y X;  1N3A A;  3L2Q A;  1M3H A;  4IL8 A;  3I0W A;  2JOI A;  1CDW A;  1HU0 A;  1RRQ A;  3TE5 A;  4B21 A;  3I0X A;  3IH7 A;  1XSZ A;  2QLV A;  1MUY A;  2F7L A;  3D4V A;  3OYK A;  3OSE A;  3OS1 A;  4AI4 A;  2OFK A;  2Y8L A;  4DK9 A;  2NOL A;  1PVS A;  2R5X A;  1TBP A;  3OY9 A;  2NLV A;  3OYE A;  2MZ8 A;  2OOY A;  1WJW A;  5BMP A;  3L2W A;  4BAC A;  1Q9U A;  2DKC A;  3S3M A;  5JN5 A;  4WXA A;  4ROD B;  2DKA A;  1PU6 A;  1KFQ A;  2OFI A;  3CWS A;  3NA5 A;  1D3U A;  2YG8 A;  3F10 A;  1W80 A;  4ZTJ A;  4B24 A;  2Z0F A;  1KYU A;  3L2V A;  1TUO A;  4BDY A;  1QN5 A;  1MPG A;  3C04 A;  3EIK A;  3OYG A;  2QRC A;  1QN4 A;  4BJU A;  4EAK A;  1QNC A;  3NNQ A;  1TBA B;  1QTP A;  3KNT A;  1P7M A;  3OYF A;  1PCJ X;  1JFI C;  1KG7 A;  2YA3 A;  3OYJ A;  1QNB A;  4YPR A;  5KN8 A;  2JHJ A;  3OYI A;  1WEI A;  1VTL E;  3ASM A; 
#chains in the Genus database with same CATH homology
 4E9G A;  1KG6 A;  3KTU A;  1ORP A;  1KQJ A;  1RRS A;  3CVT A;  1LWW A;  1N3A A;  1LWV A;  1KG3 A;  1FN7 A;  1YQR A;  1ORN A;  2ABK A;  1M3H A;  3I0W A;  4OFE A;  2I5W A;  3CWT A;  3CWA A;  1HU0 A;  1RRQ A;  4B21 A;  3I0X A;  3IH7 A;  1VRL A;  1MUY A;  4AI5 A;  1DIZ A;  2NOZ A;  3D4V A;  1YQM A;  3IHO A;  4EW0 A;  4B23 A;  4YOQ A;  4AI4 A;  2H56 A;  1P59 A;  1N3C A;  4EVV A;  1WEG A;  2OFK A;  5CHZ A;  1KG2 A;  1NKU A;  3N0U A;  3CWU A;  4DK9 A;  2NOL A;  4EJY A;  1PVS A;  3CW7 A;  1YQK A;  3CVS A;  5KN9 A;  1LMZ A;  4E9E A;  2NOB A;  1XQP A;  5DPK A;  3FSP A;  4PII A;  1PU6 A;  1NGN A;  1WEF A;  2OFI A;  4E9H A;  3CWS A;  1PU7 A;  2JHN A;  2NOH A;  4OFA A;  2YG8 A;  3F10 A;  1KO9 A;  1PU8 A;  4B24 A;  3G0Q A;  1N39 A;  2YG9 A;  4AIA A;  4UOB A;  1KG5 A;  1MUD A;  2NOE A;  3F0Z A;  1MUN A;  4EA5 A;  3N5N X;  4B22 A;  1YQL A;  1M3Q A;  4YPH A;  3OH9 A;  2JG6 A;  1MPG A;  1LWY A;  3OGD A;  1XQO A;  4EJZ A;  4OFH A;  2NOI A;  4E9F A;  3OH6 A;  4UNF A;  1XG7 A;  3KNT A;  1P7M A;  1KG4 A;  1KG7 A;  3S6I A;  1KEA A;  5AN4 A;  4HSB A;  4YPR A;  4EA4 A;  3FHF A;  2XHI A;  4EW4 A;  1EBM A;  5KN8 A;  2JHJ A;  3FHG A;  2NOF A;  1WEI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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