1Q5NA

Crystal structure of beta-carboxy-cis,cis-muconate cycloisomerase (cmle) from acinetobacter calcoaceticus sp. adp1
Total Genus 169
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
169
sequence length
444
structure length
431
Chain Sequence
QLYASLFYQRDVTEIFSDRALVSYMVEAEVALAQAQAQVGVIPQSAATVIQRAAKTAIDKIDFDALATATGLAGNIAIPFVKQLTAIVKDADEDAARYVHWGATSQDILDTACILQCRDALAIVQNQVQQCYETALSQAQTYRHQVMMGRTWLQQALPITLGHKLARWASAFKRDLDRINAIKARVLVAQLGGAVGSLASLQDQGSIVVEAYAKQLKLGQTACTWHGERDRIVEIASVLGIITGNVGKMARDWSLMMQTEIAEVFEPTRNPVAAASVLAAANRVPALMSSIYQSMVQEHERSLGAWHAEWLSLPEIFQLTAGALERTLDVLKGMEVNAENMHQNIECTHGLIMAEAVMMALAPHMGRLNAHHVVEAACKTAVAEQKHLKDIISQVDEVKQYFNPSQLDEIFKPESYLGNIQDQIDAVLQEA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords 3-carboxy-cis,cis-muconate cycloisomerase
publication title The lactonizing enzymes of the beta-ketoadipate pathway: The use of fundamentally different structural and mechanistic motifs to catalyze essentially identical reactions in the catabolism of aromatics
rcsb
source organism Acinetobacter calcoaceticus
molecule tags Isomerase
total genus 169
structure length 431
sequence length 444
ec nomenclature ec 5.5.1.2: 3-carboxy-cis,cis-muconate cycloisomerase.
pdb deposition date 2003-08-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10397 ADSL_C Adenylosuccinate lyase C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 1q5nA03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 1q5nA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 1q5nA02
4FLCA 2O6YA 1Y2MA 1GK2A 1GK3A 1U16A 1RE5A 5F92A 1K62A 1I0AA 2QGAB 3NZ4A 3GTDA 4NLEA 4CQ5A 2VD6A 1U15A 3RRPA 5HW2A 2HVGA 3R6VA 4APBA 4ADMA 1TJVA 4C6GA 5F91A 1FUOA 2FUSA 2NYNA 1DOFA 2NYFA 3R6YA 1XWOA 1GKMA 2PTQA 1T6PA 1YFEA 2O7FA 3KDZA 4BABA 1FURA 1C3CA 4NSLA 1FUQA 2YIIA 2E9FA 2PTRA 1TJUA 1AUWA 1Q5NA 2PFMA 1HY1A 3CZOA 1HY0A 1YISA 2RJSA 4BAAA 1K7WA 3GZHA 4FFXA 5D6BA 4C5SA 1YFMA 4EFCA 1GKJA 4HGVA 3C8TA 2O7BA 1KQ7A 4C5UA 4MX2A 3RD8A 1B8FA 3QBPA 3E04A 3OCEA 3NO9A 2QVEA 1TJWA 3BHGA 1VDKA 2PTSA 2RJRA 2O7DA 4V2RA 1TJ7A 1EB4A 1C3UA 2O78A 2O7EA 5EYVA 1JSWA 4APAA 4EEIA 3KDYA 2J91A 1T6JA 3UNVA 1FUPA 4V2QA 3OCFA 4C5RA 1DCNA 5EYTA 1J3UA 4ADLA 3TV2A 3R6QA 1W27A 2OHYA 2X75A
chains in the Genus database with same CATH superfamily
4FLCA 1IW7D 2O6YA 1XL7A 1Y2MA 1GK2A 1U0LA 3F4RA 1GK3A 1U16A 1RE5A 4E88A 5F92A 1K62A 1I0AA 2QGAB 3NZ4A 3GTDA 4NLEA 4CQ5A 3CRVA 2VD6A 4L6AA 1U15A 1Z4JA 3RRPA 5HW2A 2HVGA 3R6VA 4APBA 4ADMA 2I7DA 1TJVA 3U13A 4C6GA 5F91A 1FUOA 2FUSA 2FENA 2NYNA 1DOFA 2FELA 2NYFA 3R6YA 3CI0K 1XWOA 1GKMA 2PTQA 1T6PA 1YFEA 2O7FA 3KDZA 1MH9A 4BABA 2JAOA 1FURA 1C3CA 4NSLA 4MUMA 2VL7A 1FUQA 1Q91A 2YIIA 2VSFA 2E9FA 2PTRA 1TJUA 1AUWA 1Q5NA 4YIKA 2PFMA 1HY1A 1XLYA 1XMDA 3CZOA 3U19A 3CRW1 1HY0A 1YISA 2RJSA 4BAAA 1K7WA 3GZHA 4FFXA 5D6BA 5H8WA 2RCNA 1Z4QA 2JAUA 4L57A 3F4SA 4C5SA 1YFMA 1Z4IA 1XMCA 4WNLA 4EFCA 1GKJA 4HGVA 3C8TA 1XL8A 2O7BA 1KQ7A 2D27A 2YV5A 4C5UA 4MX2A 1Z4MA 3RD8A 3QBPA 1B8FA 3E04A 3OCEA 4IQJM 2JAWA 3NO9A 2QVEA 1TJWA 4MWOA 3BHGA 1VDKA 2PTSA 3BWVA 2RJRA 2O7DA 5M0JA 4V2RA 1TJ7A 1EB4A 1C3UA 5M0IA 2O78A 2O7EA 5EYVA 1JSWA 4APAA 4EEIA 3KDYA 2J91A 4YIHA 1T6JA 3UNVA 1FUPA 1Z4PX 4V2QA 3OCFA 4C5RA 4L6CA 2JARA 4A15A 1DCNA 4NFLA 5EYTA 1J3UA 1Z4LA 4ADLA 3TV2A 3F4TA 3R6QA 1T9HA 1W27A 2OHYA 1Q92A 1Z4KA 2D28C 2X75A
chains in the Genus database with same CATH topology
4FLCA 2O6YA 1Y2MA 1GK2A 1GK3A 1U16A 1RE5A 5F92A 1K62A 1I0AA 2QGAB 3NZ4A 3GTDA 4NLEA 4CQ5A 2VD6A 1U15A 3RRPA 5HW2A 2HVGA 3R6VA 4APBA 4ADMA 1TJVA 4C6GA 5F91A 1FUOA 2FUSA 2NYNA 1DOFA 2NYFA 3R6YA 1XWOA 1GKMA 2PTQA 1T6PA 1YFEA 2O7FA 3KDZA 4BABA 1FURA 1C3CA 4NSLA 1FUQA 2YIIA 2E9FA 2PTRA 1TJUA 1AUWA 1Q5NA 2PFMA 1HY1A 3CZOA 1HY0A 1YISA 2RJSA 4BAAA 1K7WA 3GZHA 4FFXA 5D6BA 4C5SA 1YFMA 4EFCA 1GKJA 4HGVA 3C8TA 2O7BA 1KQ7A 4C5UA 4MX2A 3RD8A 1B8FA 3QBPA 3E04A 3OCEA 3NO9A 2QVEA 1TJWA 3BHGA 1VDKA 2PTSA 2RJRA 2O7DA 4V2RA 1TJ7A 1EB4A 1C3UA 2O78A 2O7EA 5EYVA 1JSWA 4APAA 4EEIA 3KDYA 2J91A 1T6JA 3UNVA 1FUPA 4V2QA 3OCFA 4C5RA 1DCNA 5EYTA 1J3UA 4ADLA 3TV2A 3R6QA 1W27A 2OHYA 2X75A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FLC A;  2O6Y A;  1Y2M A;  1GK2 A;  1GK3 A;  1U16 A;  1RE5 A;  5F92 A;  1K62 A;  1I0A A;  2QGA B;  3NZ4 A;  3GTD A;  4NLE A;  4CQ5 A;  2VD6 A;  1U15 A;  3RRP A;  5HW2 A;  2HVG A;  3R6V A;  4APB A;  4ADM A;  1TJV A;  4C6G A;  5F91 A;  1FUO A;  2FUS A;  2NYN A;  1DOF A;  2NYF A;  3R6Y A;  1XWO A;  1GKM A;  2PTQ A;  1T6P A;  1YFE A;  2O7F A;  3KDZ A;  4BAB A;  1FUR A;  1C3C A;  4NSL A;  1FUQ A;  2YII A;  2E9F A;  2PTR A;  1TJU A;  1AUW A;  1Q5N A;  2PFM A;  1HY1 A;  3CZO A;  1HY0 A;  1YIS A;  2RJS A;  4BAA A;  1K7W A;  3GZH A;  4FFX A;  5D6B A;  4C5S A;  1YFM A;  4EFC A;  1GKJ A;  4HGV A;  3C8T A;  2O7B A;  1KQ7 A;  4C5U A;  4MX2 A;  3RD8 A;  1B8F A;  3QBP A;  3E04 A;  3OCE A;  3NO9 A;  2QVE A;  1TJW A;  3BHG A;  1VDK A;  2PTS A;  2RJR A;  2O7D A;  4V2R A;  1TJ7 A;  1EB4 A;  1C3U A;  2O78 A;  2O7E A;  5EYV A;  1JSW A;  4APA A;  4EEI A;  3KDY A;  2J91 A;  1T6J A;  3UNV A;  1FUP A;  4V2Q A;  3OCF A;  4C5R A;  1DCN A;  5EYT A;  1J3U A;  4ADL A;  3TV2 A;  3R6Q A;  1W27 A;  2OHY A;  2X75 A; 
#chains in the Genus database with same CATH topology
 4FLC A;  1IW7 D;  2O6Y A;  1XL7 A;  1Y2M A;  1GK2 A;  1U0L A;  3F4R A;  1GK3 A;  1U16 A;  1RE5 A;  4E88 A;  5F92 A;  1K62 A;  1I0A A;  2QGA B;  3NZ4 A;  3GTD A;  4NLE A;  4CQ5 A;  3CRV A;  2VD6 A;  4L6A A;  1U15 A;  1Z4J A;  3RRP A;  5HW2 A;  2HVG A;  3R6V A;  4APB A;  4ADM A;  2I7D A;  1TJV A;  3U13 A;  4C6G A;  5F91 A;  1FUO A;  2FUS A;  2FEN A;  2NYN A;  1DOF A;  2FEL A;  2NYF A;  3R6Y A;  3CI0 K;  1XWO A;  1GKM A;  2PTQ A;  1T6P A;  1YFE A;  2O7F A;  3KDZ A;  1MH9 A;  4BAB A;  2JAO A;  1FUR A;  1C3C A;  4NSL A;  4MUM A;  2VL7 A;  1FUQ A;  1Q91 A;  2YII A;  2VSF A;  2E9F A;  2PTR A;  1TJU A;  1AUW A;  1Q5N A;  4YIK A;  2PFM A;  1HY1 A;  1XLY A;  1XMD A;  3CZO A;  3U19 A;  3CRW 1;  1HY0 A;  1YIS A;  2RJS A;  4BAA A;  1K7W A;  3GZH A;  4FFX A;  5D6B A;  5H8W A;  2RCN A;  1Z4Q A;  2JAU A;  4L57 A;  3F4S A;  4C5S A;  1YFM A;  1Z4I A;  1XMC A;  4WNL A;  4EFC A;  1GKJ A;  4HGV A;  3C8T A;  1XL8 A;  2O7B A;  1KQ7 A;  2D27 A;  2YV5 A;  4C5U A;  4MX2 A;  1Z4M A;  3RD8 A;  3QBP A;  1B8F A;  3E04 A;  3OCE A;  4IQJ M;  2JAW A;  3NO9 A;  2QVE A;  1TJW A;  4MWO A;  3BHG A;  1VDK A;  2PTS A;  3BWV A;  2RJR A;  2O7D A;  5M0J A;  4V2R A;  1TJ7 A;  1EB4 A;  1C3U A;  5M0I A;  2O78 A;  2O7E A;  5EYV A;  1JSW A;  4APA A;  4EEI A;  3KDY A;  2J91 A;  4YIH A;  1T6J A;  3UNV A;  1FUP A;  1Z4P X;  4V2Q A;  3OCF A;  4C5R A;  4L6C A;  2JAR A;  4A15 A;  1DCN A;  4NFL A;  5EYT A;  1J3U A;  1Z4L A;  4ADL A;  3TV2 A;  3F4T A;  3R6Q A;  1T9H A;  1W27 A;  2OHY A;  1Q92 A;  1Z4K A;  2D28 C;  2X75 A; 
#chains in the Genus database with same CATH homology
 4FLC A;  2O6Y A;  1Y2M A;  1GK2 A;  1GK3 A;  1U16 A;  1RE5 A;  5F92 A;  1K62 A;  1I0A A;  2QGA B;  3NZ4 A;  3GTD A;  4NLE A;  4CQ5 A;  2VD6 A;  1U15 A;  3RRP A;  5HW2 A;  2HVG A;  3R6V A;  4APB A;  4ADM A;  1TJV A;  4C6G A;  5F91 A;  1FUO A;  2FUS A;  2NYN A;  1DOF A;  2NYF A;  3R6Y A;  1XWO A;  1GKM A;  2PTQ A;  1T6P A;  1YFE A;  2O7F A;  3KDZ A;  4BAB A;  1FUR A;  1C3C A;  4NSL A;  1FUQ A;  2YII A;  2E9F A;  2PTR A;  1TJU A;  1AUW A;  1Q5N A;  2PFM A;  1HY1 A;  3CZO A;  1HY0 A;  1YIS A;  2RJS A;  4BAA A;  1K7W A;  3GZH A;  4FFX A;  5D6B A;  4C5S A;  1YFM A;  4EFC A;  1GKJ A;  4HGV A;  3C8T A;  2O7B A;  1KQ7 A;  4C5U A;  4MX2 A;  3RD8 A;  1B8F A;  3QBP A;  3E04 A;  3OCE A;  3NO9 A;  2QVE A;  1TJW A;  3BHG A;  1VDK A;  2PTS A;  2RJR A;  2O7D A;  4V2R A;  1TJ7 A;  1EB4 A;  1C3U A;  2O78 A;  2O7E A;  5EYV A;  1JSW A;  4APA A;  4EEI A;  3KDY A;  2J91 A;  1T6J A;  3UNV A;  1FUP A;  4V2Q A;  3OCF A;  4C5R A;  1DCN A;  5EYT A;  1J3U A;  4ADL A;  3TV2 A;  3R6Q A;  1W27 A;  2OHY A;  2X75 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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