1QAEA

The active site of serratia endonuclease contains a conserved magnesium-water cluster
Total Genus 76
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
76
sequence length
240
structure length
240
Chain Sequence
IDNCAVGCPTGGSSNVSIVRHAYTLNNNSTTKFANWVAYHITKDTPASGKTRNWKTDPALNPADTLAPADYTGANAALKVDRGHQAPLASLAGVSDWESLNYLSNITPQKSDLNQGAWARLEDQERKLIDRADISSVYTVTGPLYERDMGKLPGTQKAHTIPSAYWKVIFINNSPAVNHYAAFLFDQNTPKGADFCQFRVTVDEIEKRTGLIIWAGLPDDVQASLKSKPGVLPELMGCKN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The active site of Serratia endonuclease contains a conserved magnesium-water cluster.
pubmed doi rcsb
molecule tags Endonuclease
source organism Serratia marcescens
molecule keywords PROTEIN (EXTRACELLULAR ENDONUCLEASE)
total genus 76
structure length 240
sequence length 240
chains with identical sequence B
ec nomenclature ec 3.1.30.2: Serratia marcescens nuclease.
pdb deposition date 1999-03-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01223 Endonuclease_NS DNA/RNA non-specific endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.570.10 Alpha Beta 3-Layer(aba) Sandwich Extracellular Endonuclease; Chain A Extracellular Endonuclease, subunit A 1qaeA00
4GTXA 3WAYA 3ISMA 5GKPA 5LQQA 3NKPA 2XRGA 3WAVA 5L0BA 4E3YA 5HRTA 4A1NA 3NKRA 4QGOA 5IJSA 1QAEA 5KXAA 1QL0A 5DLVA 5L0KA 3NKMA 2XR9A 3NKNA 5DLTA 4ZG6A 1SMNA 2O3BA 4QH0A 4ZG9A 3NKOA 5DLWA 1G8TA 4GTYA 5GKCA 4QN0A 3WAWA 2XH3A 5L0EA 5INHA 2XGRA 4B56A 3OWVA 4GTWA 4ZGAA 5IJQA 1ZM8A 3NKQA 4GTZA 4ZG7A 3WAXA 5LIAA 3S5BA
chains in the Genus database with same CATH superfamily
4GTXA 3WAYA 3ISMA 5GKPA 5LQQA 3NKPA 2XRGA 3WAVA 5L0BA 4E3YA 5HRTA 4A1NA 3NKRA 4QGOA 5IJSA 1QAEA 5KXAA 1QL0A 5DLVA 5L0KA 3NKMA 2XR9A 3NKNA 5DLTA 4ZG6A 1SMNA 2O3BA 4QH0A 4ZG9A 3NKOA 5DLWA 1G8TA 4GTYA 5GKCA 4QN0A 3WAWA 2XH3A 5L0EA 5INHA 2XGRA 4B56A 3OWVA 4GTWA 4ZGAA 5IJQA 1ZM8A 3NKQA 4GTZA 4ZG7A 3WAXA 5LIAA 3S5BA
chains in the Genus database with same CATH topology
4GTXA 3WAYA 3ISMA 5GKPA 5LQQA 3NKPA 2XRGA 3WAVA 5L0BA 4E3YA 5HRTA 4A1NA 3NKRA 4QGOA 5IJSA 1QAEA 5KXAA 1QL0A 5DLVA 5L0KA 3NKMA 2XR9A 3NKNA 5DLTA 4ZG6A 1SMNA 2O3BA 4QH0A 4ZG9A 3NKOA 5DLWA 1G8TA 4GTYA 5GKCA 4QN0A 3WAWA 2XH3A 5L0EA 5INHA 2XGRA 4B56A 3OWVA 4GTWA 4ZGAA 5IJQA 1ZM8A 3NKQA 4GTZA 4ZG7A 3WAXA 5LIAA 3S5BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4GTX A;  3WAY A;  3ISM A;  5GKP A;  5LQQ A;  3NKP A;  2XRG A;  3WAV A;  5L0B A;  4E3Y A;  5HRT A;  4A1N A;  3NKR A;  4QGO A;  5IJS A;  1QAE A;  5KXA A;  1QL0 A;  5DLV A;  5L0K A;  3NKM A;  2XR9 A;  3NKN A;  5DLT A;  4ZG6 A;  1SMN A;  2O3B A;  4QH0 A;  4ZG9 A;  3NKO A;  5DLW A;  1G8T A;  4GTY A;  5GKC A;  4QN0 A;  3WAW A;  2XH3 A;  5L0E A;  5INH A;  2XGR A;  4B56 A;  3OWV A;  4GTW A;  4ZGA A;  5IJQ A;  1ZM8 A;  3NKQ A;  4GTZ A;  4ZG7 A;  3WAX A;  5LIA A;  3S5B A; 
#chains in the Genus database with same CATH topology
 4GTX A;  3WAY A;  3ISM A;  5GKP A;  5LQQ A;  3NKP A;  2XRG A;  3WAV A;  5L0B A;  4E3Y A;  5HRT A;  4A1N A;  3NKR A;  4QGO A;  5IJS A;  1QAE A;  5KXA A;  1QL0 A;  5DLV A;  5L0K A;  3NKM A;  2XR9 A;  3NKN A;  5DLT A;  4ZG6 A;  1SMN A;  2O3B A;  4QH0 A;  4ZG9 A;  3NKO A;  5DLW A;  1G8T A;  4GTY A;  5GKC A;  4QN0 A;  3WAW A;  2XH3 A;  5L0E A;  5INH A;  2XGR A;  4B56 A;  3OWV A;  4GTW A;  4ZGA A;  5IJQ A;  1ZM8 A;  3NKQ A;  4GTZ A;  4ZG7 A;  3WAX A;  5LIA A;  3S5B A; 
#chains in the Genus database with same CATH homology
 4GTX A;  3WAY A;  3ISM A;  5GKP A;  5LQQ A;  3NKP A;  2XRG A;  3WAV A;  5L0B A;  4E3Y A;  5HRT A;  4A1N A;  3NKR A;  4QGO A;  5IJS A;  1QAE A;  5KXA A;  1QL0 A;  5DLV A;  5L0K A;  3NKM A;  2XR9 A;  3NKN A;  5DLT A;  4ZG6 A;  1SMN A;  2O3B A;  4QH0 A;  4ZG9 A;  3NKO A;  5DLW A;  1G8T A;  4GTY A;  5GKC A;  4QN0 A;  3WAW A;  2XH3 A;  5L0E A;  5INH A;  2XGR A;  4B56 A;  3OWV A;  4GTW A;  4ZGA A;  5IJQ A;  1ZM8 A;  3NKQ A;  4GTZ A;  4ZG7 A;  3WAX A;  5LIA A;  3S5B A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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