1QAGA

Actin binding region of the dystrophin homologue utrophin
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
226
structure length
226
Chain Sequence
DVQKKTFTKWINARFSKSGKPPINDMFTDLKDGRKLLDLLEGLTGTSLPKERGSTRVHALNNVNRVLQVLHQNNVELVNIGGTDIVDGNHKLTLGLLWSIILHWQVKDVMKDVMSDLQQTNSEKILLSWVRQTTRPYSQVNVLNFTTSWTDGLAFNAVLHRHKPDLFSWDKVVKMSPIERLEHAFSKAQTYLGIEKLLDPEDVAVRLPDKKSIIMYLTSLFEVLPQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the actin-binding region of utrophin reveals a head-to-tail dimer
pubmed doi rcsb
molecule tags Structural protein
source organism Homo sapiens
molecule keywords UTROPHIN ACTIN BINDING REGION
total genus 69
structure length 226
sequence length 226
chains with identical sequence B
ec nomenclature
pdb deposition date 1999-03-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00307 CH Calponin homology (CH) domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.418.10 Mainly Alpha Orthogonal Bundle Actin-binding Protein, T-fimbrin; domain 1 Calponin-like domain 1qagA02
1.10.418.10 Mainly Alpha Orthogonal Bundle Actin-binding Protein, T-fimbrin; domain 1 Calponin-like domain 1qagA01
1RT8A 1WKUA 2EE7A 4Q59A 2VZCA 2D85A 1PA7A 3HOCA 2QJZA 2EYIA 1SH5A 1MB8A 2VZIB 3JARM 1PXYA 1VKAA 1WYOA 3KY9A 1UJOA 5BVRA 1P2XA 2JV9A 3HORA 1WIXA 1H67A 2E9KA 4TXIA 2R8UA 3F7PA 1SH6A 1TJTA 5A4BA 4B7LA 1WYMA 2K3SA 4Q57B 1BKRA 3I6XA 1WYNA 1QAGA 1AOAA 3CO1A 1DXXA 1WYRA 2R0OA 2QJXA 2YRNA 4TXKA 2VZDA 3KMUB 4EDMA 2WA7A 2D88A 3REPB 1WYQA 3JALM 3KMWB 4Q58A 1BHDA 5A38A 5L0OA 1AA2A 3HOPA 2RR8A 4EDLA 2D86A 2DK9A 2D87A 2WFNA 1WYLA 4EDNA 5J8EA 2EYNA 2K2RA 2WA6A 1WJOA 3FERA 2WA5A 1V5KA 1WYPA 2VZGB 1P5SA 2L3GA 5A36A 2D89A 1UEGA 5A37A 3JAKM
chains in the Genus database with same CATH superfamily
1RT8A 1WKUA 2EE7A 4Q59A 2VE7A 2VZCA 2D85A 1PA7A 3HOCA 2QJZA 4LVRA 2EYIA 1SH5A 1MB8A 2VZIB 3JARM 1PXYA 1VKAA 1WYOA 3KY9A 1UJOA 5BVRA 1P2XA 2JV9A 3HORA 2WE6A 1WIXA 2HKPA 1H67A 2E9KA 3EAYA 4TXIA 2R8UA 2EQOA 3F7PA 1SH6A 1TJTA 5A4BA 4B7LA 1WYMA 2K3SA 4Q57B 1BKRA 3I6XA 1WYNA 5FMTA 1QAGA 1AOAA 1EUVA 3CO1A 2HL9A 1DXXA 1WYRA 2R0OA 2QJXA 2YRNA 2WDTA 4TXKA 2VZDA 3KMUB 4EDMA 2WA7A 2D88A 3REPB 4LVPA 2IGPA 1WYQA 3JALM 3KMWB 4Q58A 1BHDA 5A38A 4DDPA 3VP7A 5L0OA 1AA2A 3HOPA 2RR8A 4EDLA 2D86A 2DK9A 2D87A 2WFNA 1WYLA 4EDNA 5J8EA 2EYNA 2HL8A 2K2RA 2WA6A 1WJOA 2VE7C 3FERA 2WA5A 1V5KA 1WYPA 5FMUA 2VZGB 1P5SA 2L3GA 5A36A 2D89A 1UEGA 5A37A 3JAKM
chains in the Genus database with same CATH topology
1RT8A 1WKUA 2EE7A 4Q59A 2VZCA 2D85A 1PA7A 3HOCA 2QJZA 2EYIA 1SH5A 1MB8A 2VZIB 3JARM 1PXYA 1VKAA 1WYOA 3KY9A 1UJOA 5BVRA 1P2XA 2JV9A 3HORA 1WIXA 1H67A 2E9KA 4TXIA 2R8UA 3F7PA 1SH6A 1TJTA 5A4BA 4B7LA 1WYMA 2K3SA 4Q57B 1BKRA 3I6XA 1WYNA 1QAGA 1AOAA 3CO1A 1DXXA 1WYRA 2R0OA 2QJXA 2YRNA 4TXKA 2VZDA 3KMUB 4EDMA 2WA7A 2D88A 3REPB 1WYQA 3JALM 3KMWB 4Q58A 1BHDA 5A38A 5L0OA 1AA2A 3HOPA 2RR8A 4EDLA 2D86A 2DK9A 2D87A 2WFNA 1WYLA 4EDNA 5J8EA 2EYNA 2K2RA 2WA6A 1WJOA 3FERA 2WA5A 1V5KA 1WYPA 2VZGB 1P5SA 2L3GA 5A36A 2D89A 1UEGA 5A37A 3JAKM
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RT8 A;  1WKU A;  2EE7 A;  4Q59 A;  2VZC A;  2D85 A;  1PA7 A;  3HOC A;  2QJZ A;  2EYI A;  1SH5 A;  1MB8 A;  2VZI B;  3JAR M;  1PXY A;  1VKA A;  1WYO A;  3KY9 A;  1UJO A;  5BVR A;  1P2X A;  2JV9 A;  3HOR A;  1WIX A;  1H67 A;  2E9K A;  4TXI A;  2R8U A;  3F7P A;  1SH6 A;  1TJT A;  5A4B A;  4B7L A;  1WYM A;  2K3S A;  4Q57 B;  1BKR A;  3I6X A;  1WYN A;  1QAG A;  1AOA A;  3CO1 A;  1DXX A;  1WYR A;  2R0O A;  2QJX A;  2YRN A;  4TXK A;  2VZD A;  3KMU B;  4EDM A;  2WA7 A;  2D88 A;  3REP B;  1WYQ A;  3JAL M;  3KMW B;  4Q58 A;  1BHD A;  5A38 A;  5L0O A;  1AA2 A;  3HOP A;  2RR8 A;  4EDL A;  2D86 A;  2DK9 A;  2D87 A;  2WFN A;  1WYL A;  4EDN A;  5J8E A;  2EYN A;  2K2R A;  2WA6 A;  1WJO A;  3FER A;  2WA5 A;  1V5K A;  1WYP A;  2VZG B;  1P5S A;  2L3G A;  5A36 A;  2D89 A;  1UEG A;  5A37 A;  3JAK M; 
#chains in the Genus database with same CATH topology
 1RT8 A;  1WKU A;  2EE7 A;  4Q59 A;  2VE7 A;  2VZC A;  2D85 A;  1PA7 A;  3HOC A;  2QJZ A;  4LVR A;  2EYI A;  1SH5 A;  1MB8 A;  2VZI B;  3JAR M;  1PXY A;  1VKA A;  1WYO A;  3KY9 A;  1UJO A;  5BVR A;  1P2X A;  2JV9 A;  3HOR A;  2WE6 A;  1WIX A;  2HKP A;  1H67 A;  2E9K A;  3EAY A;  4TXI A;  2R8U A;  2EQO A;  3F7P A;  1SH6 A;  1TJT A;  5A4B A;  4B7L A;  1WYM A;  2K3S A;  4Q57 B;  1BKR A;  3I6X A;  1WYN A;  5FMT A;  1QAG A;  1AOA A;  1EUV A;  3CO1 A;  2HL9 A;  1DXX A;  1WYR A;  2R0O A;  2QJX A;  2YRN A;  2WDT A;  4TXK A;  2VZD A;  3KMU B;  4EDM A;  2WA7 A;  2D88 A;  3REP B;  4LVP A;  2IGP A;  1WYQ A;  3JAL M;  3KMW B;  4Q58 A;  1BHD A;  5A38 A;  4DDP A;  3VP7 A;  5L0O A;  1AA2 A;  3HOP A;  2RR8 A;  4EDL A;  2D86 A;  2DK9 A;  2D87 A;  2WFN A;  1WYL A;  4EDN A;  5J8E A;  2EYN A;  2HL8 A;  2K2R A;  2WA6 A;  1WJO A;  2VE7 C;  3FER A;  2WA5 A;  1V5K A;  1WYP A;  5FMU A;  2VZG B;  1P5S A;  2L3G A;  5A36 A;  2D89 A;  1UEG A;  5A37 A;  3JAK M; 
#chains in the Genus database with same CATH homology
 1RT8 A;  1WKU A;  2EE7 A;  4Q59 A;  2VZC A;  2D85 A;  1PA7 A;  3HOC A;  2QJZ A;  2EYI A;  1SH5 A;  1MB8 A;  2VZI B;  3JAR M;  1PXY A;  1VKA A;  1WYO A;  3KY9 A;  1UJO A;  5BVR A;  1P2X A;  2JV9 A;  3HOR A;  1WIX A;  1H67 A;  2E9K A;  4TXI A;  2R8U A;  3F7P A;  1SH6 A;  1TJT A;  5A4B A;  4B7L A;  1WYM A;  2K3S A;  4Q57 B;  1BKR A;  3I6X A;  1WYN A;  1QAG A;  1AOA A;  3CO1 A;  1DXX A;  1WYR A;  2R0O A;  2QJX A;  2YRN A;  4TXK A;  2VZD A;  3KMU B;  4EDM A;  2WA7 A;  2D88 A;  3REP B;  1WYQ A;  3JAL M;  3KMW B;  4Q58 A;  1BHD A;  5A38 A;  5L0O A;  1AA2 A;  3HOP A;  2RR8 A;  4EDL A;  2D86 A;  2DK9 A;  2D87 A;  2WFN A;  1WYL A;  4EDN A;  5J8E A;  2EYN A;  2K2R A;  2WA6 A;  1WJO A;  3FER A;  2WA5 A;  1V5K A;  1WYP A;  2VZG B;  1P5S A;  2L3G A;  5A36 A;  2D89 A;  1UEG A;  5A37 A;  3JAK M; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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