1QQGA

Crystal structure of the ph-ptb targeting region of irs-1
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
251
structure length
207
Chain Sequence
DVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAPKRSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHAFKEVWQVILKPKGLGQTKNLIGIYRLCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQVDDSVVAQNMHETILEAMRAMSD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords INSULIN RECEPTOR SUBSTRATE 1
publication title Crystal structure of the pleckstrin homology-phosphotyrosine binding (PH-PTB) targeting region of insulin receptor substrate 1.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Signal transduction
total genus 51
structure length 207
sequence length 251
chains with identical sequence B
ec nomenclature
pdb deposition date 1999-06-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00169 PH PH domain
A PF02174 IRS PTB domain (IRS-1 type)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 1qqgA02
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 1qqgA01
3T06A 5KCVA 2RLOA 3P7ZA 4TYZA 2D9ZA 3SV1A 2EC1A 3CIKA 1GG3A 1WVHA 1UNPA 1MK7B 2RSGA 1ZC3B 2XQNM 3KZ1A 1MIXA 1J19A 3RCPA 2MWNB 1EAZA 2LOZA 1WJ1A 2DYQA 2Y8GA 2NZ8B 3F0WA 4HAWB 3TVVA 1V88A 1U5FA 5C16A 3A98B 2Z0OA 1U5GA 2FJLA 1I7AA 5KQ4A 3QBVB 4HDOA 4DX8A 1MPHA 2Z0QA 1FHXA 1EF1A 4DBBA 4GMXB 5LONB 3TFMA 3PSCA 5D3YA 1U27A 2I5FA 4KVGB 2YT1A 3ULCA 2LYDA 1H10A 2D11A 1GC7A 3ZVRA 2Y8FA 3ODOA 2QKLA 1V89A 2YSZA 2H7DA 1MKEA 3IVFA 2H7EA 3GYPA 4PNKA 3F5RA 1OQNA 2MFQA 2DFKA 2EJ8A 3ULBA 1FAOA 2CY4A 4MY6A 3KY9A 5J3YA 3FSSA 4Y94A 2UVMA 4F7UP 1BWNA 5L81A 3TW1A 1QC6A 2DHJA 2DHKA 1PMSA 3SYXA 3GYOA 2VKIA 2COFA 3PZDA 4F7GA 2UZRA 1Z87A 4KAXB 3O96A 1P5TA 4ZRJA 2GJYA 4TKNA 4KHAA 5KQ1A 1X11A 2D2QA 2GCLA 2W2WA 4K2PA 2DTCA 2L1CA 3BINA 1W1HA 1XKEA 2J0MA 3PVLA 2COCA 1P6SA 2DKPA 2G35A 2LOXA 5D27A 4IAPA 1MK9B 2R09A 2RVBB 3HW2B 1X1GA 4WVFB 2P0HA 2MKRA 2LG1A 3SNHA 2RNRB 3KRXA 3U7DA 1DDVA 1DDMA 2Y7BA 4MK0A 1XODA 1Q67A 4HB0B 1SGHA 4GMVA 4L6EA 3WYFB 3SUZA 3MPXA 2MDXA 4A6KA 3QWMA 2I5CA 2DLWA 1XD4A 4YONA 1V61A 3D8DA 1Y5OA 2AEHA 3VIAA 2I1KA 4YL8A 5JHGA 5DIFB 1UPQA 3KSYA 1SHCA 1X1FA 3KRWA 3D8EA 1BAKA 1V5UA 4HAUB 4A6FA 4HB3B 2DX1A 2N0YA 2P0DA 1NU2A 1WGUA 1TXDA 2DX5A 2AL6A 4H8SA 4HATB 1ZSQA 5HE2A 4GXBA 3SO6A 2RGNB 4XWXA 1P3RA 5DI9B 2VSZA 1XCGA 1M7RA 2GS0A 3BJIA 2DYNA 2HTHB 1X86A 5DH9B 1MAIA 1RRPB 4C0AA 4ZRIA 5DHAB 1WG7A 1OMWA 1M7EA 4EJNA 4MT7A 2M38A 5CLQB 1W1GA 4WJ7A 2OQBA 2ZPYA 3A8PA 2D9VA 2LKOA 1WI1A 1U2BA 2DA0A 4KHOA 3ML4A 5HE0A 1QQGA 2J59M 4A6FB 3ZDTA 1E5WA 1WJMA 2ROZB 4K2OA 3AJ4A 1N3HA 2YVCA 2ELAA 1V5MA 2DHIA 1UPRA 1PLSA 1DYNA 3QIJA 1FOEA 1K5DB 2R0DA 3CXBB 4B6HA 2ELBA 2CRFA 1FHOA 3OANA 1XX0A 5D3WA 3WA0A 2KCJA 4WSFA 3HK0A 4HAYB 1XR0B 1DROA 2Q13A 2YS1A 1RJ2A 2CODA 3VOQA 2V76A 3PVUA 5HE3A 3V5WA 4HAVB 5HE1A 4EKUA 3DXEA 1ZC4B 2OTXA 1BTNA 4ZRKA 5C79A 3A8QA 2I1JA 2ADZA 2N23A 5C5BA 1EGXA 2M14A 1J0WA 4IOYX 1ZVRA 2DN6A 2X18A 1PFJA 1AQCA 2P8VA 2K2JA 3M1IB 1ISNA 2E2XA 2EMSA 2KUPA 4CHJA 1IRSA 2W2XC 2UZSA 1FB8A 5FI0A 1ZM0A 3HQCA 2HE7A 2QKMA 1BTKA 2RUKB 4HAXB 4GZUA 4D0NB 2W2XD 2KGXB 2GCJA 1MIZB 5CLLB 3TCAA 2K00A 3ODXA 3NSUA 3U8ZA 4CYEA 1FHWA 1NTYA 2CY5A 4GPTB 1EVHA 1NI2A 2L2IA 3AU4A 1K5GB 3ODWA 2JP2A 1FGYA 2D10A 1U5DA 2NMBA 3FEHA 1V5PA 4HB2B 3D8FA 2P0FA 2D4QA 3FM8C 2EMTA 4P7IA 2YRYA 2D9YA 2J0KA 5C5BB 2YS5A 5DHFB 1LW3A 3PP2A 5J3TA 1B55A 3N7CA 2YF0A 1H4RA 1KZ7A 4PQ0A 4DX90 2K2UA 5FI1A 2IFSA 1U29A 2ROVA 4HB4B 4CHMA 5GOWB 1KI1B 1KZGA 4DXAB 1TJ6A 4A6HA 5JP4A 3DXDA 5C6RA 4GN1A 5D3XA 3TO1A 1WGQA 2PZ1A 2DKQA 4KHBB 2J0JA 1UNRA 4HDQA 4K17A 1OY2A 1FGZA 2YS3A 2COAA 2BCJA 2CAYA 5EFXA 5J3QA 1I2HA 1DBHA 1LB1A 2D9WA 4NY0A 2VRWB 5LOPB 1W1DA 2IYBA 1GC6A 3UZTA 4HHVA 4Z2NA 5JHHA 4A5KA 4EMOA 3X23A 3P6AA 4NSWA 1TQZA 4K81A 4BBKA 2YT0A 1UNQA 4HAZB 3MDBC 1UEFA 1DDWA 5JLJB 3DXCA 4F7HA 3PEGA 1AWEA 1Y19B 4Z2MB 1U5EA 2D9XA 2LULA 4IFSA 3PVWA 3G9WA 3PG7A 2Z0PA 1NTVA 1X05A 3LJUX 3AU5A 5D3VA
chains in the Genus database with same CATH superfamily
3T06A 5KCVA 2RLOA 3P7ZA 4TYZA 2D9ZA 3SV1A 2EC1A 3CIKA 1GG3A 1WVHA 3A58A 1UNPA 2KIGA 1MK7B 2RSGA 1ZC3B 2XQNM 3KZ1A 1MIXA 1J19A 3RCPA 2MWNB 2Z13A 1EAZA 2K8EA 2LOZA 1WJ1A 2DYQA 2Y8GA 2NZ8B 3F0WA 4HAWB 3TVVA 1V88A 1U5FA 2GUMA 5C16A 3A98B 2Z0OA 1U5GA 2FJLA 1I7AA 5KQ4A 3QBVB 4HDOA 4DX8A 1MPHA 2Z0QA 1FHXA 1EF1A 4DBBA 4GMXB 5LONB 3TFMA 3NW8A 3PSCA 5D3YA 1U27A 2I5FA 4KVGB 2YT1A 3ULCA 2LYDA 1H10A 2D11A 1GC7A 4GNKB 3ZVRA 2Y8FA 3ODOA 2QKLA 1V89A 2YSZA 2H7DA 1MKEA 3IVFA 2H7EA 4QXAB 3GYPA 4PNKA 3F5RA 1OQNA 2MFQA 2DFKA 2EJ8A 3ULBA 1FAOA 2CY4A 4MY6A 3KY9A 5J3YA 3FSSA 4Y94A 2UVMA 4F7UP 1BWNA 5L81A 4L1RA 3TW1A 1QC6A 2DHJA 2DHKA 1PMSA 3SYXA 3GYOA 2VKIA 2COFA 3B77A 3HSAA 3PZDA 4F7GA 2UZRA 1Z87A 4KAXB 3O96A 1P5TA 4ZRJA 4D6WA 2GJYA 4TKNA 4KHAA 5KQ1A 1X11A 2D2QA 2GCLA 2W2WA 4K2PA 2DTCA 2L1CA 3BINA 2Z4DA 1W1HA 1XKEA 2J0MA 3PVLA 2COCA 1P6SA 2DKPA 2G35A 2LOXA 5D27A 4IAPA 1MK9B 2R09A 2RVBB 3HW2B 1X1GA 4WVFB 4DIXA 2P0HA 2MKRA 2LG1A 3SNHA 2RNRB 3KRXA 3U7DA 1DDVA 1DDMA 2Y7BA 4MK0A 1XODA 1Q67A 4HB0B 1SGHA 4GMVA 5IRSA 4L6EA 3WYFB 3SUZA 4QJ4B 3MPXA 2MDXA 4A6KA 3QWMA 2I5CA 2DLWA 1XD4A 4YONA 1V61A 3D8DA 1Y5OA 2Z59A 2AEHA 3VIAA 2I1KA 4YL8A 5JHGA 5DIFB 1UPQA 3KSYA 1SHCA 1X1FA 3KRWA 3D8EA 1BAKA 1V5UA 4HAUB 4A6FA 4HB3B 2DX1A 2K49A 4QJ3B 1MI1A 2N0YA 2P0DA 1NU2A 1WGUA 1TXDA 4KHBA 2DX5A 2AL6A 4H8SA 4HATB 1ZSQA 5HE2A 4GXBA 3SO6A 2RGNB 4XWXA 1P3RA 5DI9B 2VSZA 1XCGA 1M7RA 2GS0A 3BJIA 2DYNA 2HTHB 1X86A 5DH9B 1MAIA 1RRPB 4GOUA 4ZRIA 4C0AA 5DHAB 1WG7A 1OMWA 1M7EA 4EJNA 4CSQA 4MT7A 4HSIA 2M38A 5CLQB 1W1GA 4WJ7A 2Z14A 2OQBA 2ZPYA 2KIEA 3A8PA 1ZYIA 2D9VA 2LKOA 1WI1A 5I2MA 5LG4B 1U2BA 2DA0A 4KHOA 3ML4A 5HE0A 1QQGA 2J59M 4A6FB 3ZDTA 1E5WA 1WJMA 2ROZB 4K2OA 3AJ4A 1N3HA 2YVCA 2ELAA 1V5MA 2DHIA 1UPRA 1PLSA 1DYNA 3QIJA 1FOEA 1K5DB 4QJ5B 2R0DA 3FVCA 3CXBB 4B6HA 2ELBA 2CRFA 1FHOA 3OANA 1XX0A 5D3WA 3WA0A 1T77A 2KCJA 4WSFA 4OSNA 3HK0A 4HAYB 1XR0B 1DROA 2Q13A 2YS1A 1RJ2A 2CODA 3HIEA 3VOQA 2V76A 3PVUA 5HE3A 3V5WA 4HAVB 5HE1A 4EKUA 3DXEA 1ZC4B 2OTXA 1BTNA 4ZRKA 5C79A 2R2YA 3A8QA 2I1JA 2ADZA 2N23A 5C5BA 1EGXA 2M14A 1J0WA 4IOYX 1ZVRA 2DN6A 2X18A 1PFJA 1AQCA 2P8VA 2K2JA 3M1IB 1ISNA 2E2XA 2EMSA 2KUPA 4CHJA 1IRSA 2W2XC 2UZSA 1FB8A 5FI0A 1ZM0A 3HQCA 2HE7A 2QKMA 2KR0A 1BTKA 2RUKB 4HAXB 4GZUA 4D0NB 2W2XD 2KGXB 2GCJA 1MIZB 5CLLB 3TCAA 2K00A 3ODXA 3NSUA 3U8ZA 4CYEA 1FHWA 1NTYA 2CY5A 4GPTB 1EVHA 1NI2A 2L2IA 3AU4A 1K5GB 3ODWA 5I2SA 3DCXA 2JP2A 2NBVA 1FGYA 2D10A 1U5DA 2NMBA 3FEHA 3NWDA 1V5PA 4HB2B 3D8FA 2P0FA 5M4YB 2D4QA 3FM8C 2EMTA 4P7IA 2YRYA 2D9YA 2J0KA 5C5BB 2YS5A 5DHFB 1LW3A 3PP2A 5J3TA 1B55A 3N7CA 2FJUB 2YF0A 1H4RA 1KZ7A 4PQ0A 4DX90 2K2UA 5FI1A 2IFSA 3NWFA 1U29A 2ROVA 4HB4B 4CHMA 5GOWB 1KI1B 1KZGA 4DXAB 1TJ6A 2KUQA 3OHMB 4A6HA 5JP4A 3DXDA 5C6RA 4GN1A 5D3XA 3TO1A 1WGQA 2PZ1A 2DKQA 4KHBB 2J0JA 1UNRA 4HDQA 3NWAA 4K17A 1OY2A 1FGZA 2YS3A 2COAA 2BCJA 2CAYA 5EFXA 5J3QA 1I2HA 1DBHA 1LB1A 2D9WA 4NY0A 2VRWB 5LOPB 1W1DA 2IYBA 1GC6A 3UZTA 4HHVA 4Z2NA 5JHHA 4A5KA 4EMOA 3X23A 3P6AA 4NSWA 1TQZA 4K81A 4BBKA 2YT0A 1UNQA 2RRFA 4HAZB 3MDBC 1UEFA 1DDWA 5JLJB 3DXCA 4F7HA 3PEGA 1AWEA 1Y19B 4Z2MB 1U5EA 2YT2A 2D9XA 2LULA 3U12A 4IFSA 4OT1A 3PVWA 3G9WA 3PG7A 2ZKMX 2Z0PA 1NTVA 1X05A 3LJUX 3AU5A 5D3VA
chains in the Genus database with same CATH topology
3T06A 5KCVA 2RLOA 3P7ZA 4TYZA 2D9ZA 3SV1A 2EC1A 3CIKA 1GG3A 1WVHA 1UNPA 1MK7B 2RSGA 1ZC3B 2XQNM 3KZ1A 1MIXA 1J19A 3RCPA 2MWNB 1EAZA 2LOZA 1WJ1A 2DYQA 2Y8GA 2NZ8B 3F0WA 4HAWB 3TVVA 1V88A 1U5FA 5C16A 3A98B 2Z0OA 1U5GA 2FJLA 1I7AA 5KQ4A 3QBVB 4HDOA 4DX8A 1MPHA 2Z0QA 1FHXA 1EF1A 4DBBA 4GMXB 5LONB 3TFMA 3PSCA 5D3YA 1U27A 2I5FA 4KVGB 2YT1A 3ULCA 2LYDA 1H10A 2D11A 1GC7A 3ZVRA 2Y8FA 3ODOA 2QKLA 1V89A 2YSZA 2H7DA 1MKEA 3IVFA 2H7EA 3GYPA 4PNKA 3F5RA 1OQNA 2MFQA 2DFKA 2EJ8A 3ULBA 1FAOA 2CY4A 4MY6A 3KY9A 5J3YA 3FSSA 4Y94A 2UVMA 4F7UP 1BWNA 5L81A 3TW1A 1QC6A 2DHJA 2DHKA 1PMSA 3SYXA 3GYOA 2VKIA 2COFA 3PZDA 4F7GA 2UZRA 1Z87A 4KAXB 3O96A 1P5TA 4ZRJA 2GJYA 4TKNA 4KHAA 5KQ1A 1X11A 2D2QA 2GCLA 2W2WA 4K2PA 2DTCA 2L1CA 3BINA 1W1HA 1XKEA 2J0MA 3PVLA 2COCA 1P6SA 2DKPA 2G35A 2LOXA 5D27A 4IAPA 1MK9B 2R09A 2RVBB 3HW2B 1X1GA 4WVFB 2P0HA 2MKRA 2LG1A 3SNHA 2RNRB 3KRXA 3U7DA 1DDVA 1DDMA 2Y7BA 4MK0A 1XODA 1Q67A 4HB0B 1SGHA 4GMVA 4L6EA 3WYFB 3SUZA 3MPXA 2MDXA 4A6KA 3QWMA 2I5CA 2DLWA 1XD4A 4YONA 1V61A 3D8DA 1Y5OA 2AEHA 3VIAA 2I1KA 4YL8A 5JHGA 5DIFB 1UPQA 3KSYA 1SHCA 1X1FA 3KRWA 3D8EA 1BAKA 1V5UA 4HAUB 4A6FA 4HB3B 2DX1A 2N0YA 2P0DA 1NU2A 1WGUA 1TXDA 2DX5A 2AL6A 4H8SA 4HATB 1ZSQA 5HE2A 4GXBA 3SO6A 2RGNB 4XWXA 1P3RA 5DI9B 2VSZA 1XCGA 1M7RA 2GS0A 3BJIA 2DYNA 2HTHB 1X86A 5DH9B 1MAIA 1RRPB 4C0AA 4ZRIA 5DHAB 1WG7A 1OMWA 1M7EA 4EJNA 4MT7A 2M38A 5CLQB 1W1GA 4WJ7A 2OQBA 2ZPYA 3A8PA 2D9VA 2LKOA 1WI1A 1U2BA 2DA0A 4KHOA 3ML4A 5HE0A 1QQGA 2J59M 4A6FB 3ZDTA 1E5WA 1WJMA 2ROZB 4K2OA 3AJ4A 1N3HA 2YVCA 2ELAA 1V5MA 2DHIA 1UPRA 1PLSA 1DYNA 3QIJA 1FOEA 1K5DB 2R0DA 3CXBB 4B6HA 2ELBA 2CRFA 1FHOA 3OANA 1XX0A 5D3WA 3WA0A 2KCJA 4WSFA 3HK0A 4HAYB 1XR0B 1DROA 2Q13A 2YS1A 1RJ2A 2CODA 3VOQA 2V76A 3PVUA 5HE3A 3V5WA 4HAVB 5HE1A 4EKUA 3DXEA 1ZC4B 2OTXA 1BTNA 4ZRKA 5C79A 3A8QA 2I1JA 2ADZA 2N23A 5C5BA 1EGXA 2M14A 1J0WA 4IOYX 1ZVRA 2DN6A 2X18A 1PFJA 1AQCA 2P8VA 2K2JA 3M1IB 1ISNA 2E2XA 2EMSA 2KUPA 4CHJA 1IRSA 2W2XC 2UZSA 1FB8A 5FI0A 1ZM0A 3HQCA 2HE7A 2QKMA 1BTKA 2RUKB 4HAXB 4GZUA 4D0NB 2W2XD 2KGXB 2GCJA 1MIZB 5CLLB 3TCAA 2K00A 3ODXA 3NSUA 3U8ZA 4CYEA 1FHWA 1NTYA 2CY5A 4GPTB 1EVHA 1NI2A 2L2IA 3AU4A 1K5GB 3ODWA 2JP2A 1FGYA 2D10A 1U5DA 2NMBA 3FEHA 1V5PA 4HB2B 3D8FA 2P0FA 2D4QA 3FM8C 2EMTA 4P7IA 2YRYA 2D9YA 2J0KA 5C5BB 2YS5A 5DHFB 1LW3A 3PP2A 5J3TA 1B55A 3N7CA 2YF0A 1H4RA 1KZ7A 4PQ0A 4DX90 2K2UA 5FI1A 2IFSA 1U29A 2ROVA 4HB4B 4CHMA 5GOWB 1KI1B 1KZGA 4DXAB 1TJ6A 4A6HA 5JP4A 3DXDA 5C6RA 4GN1A 5D3XA 3TO1A 1WGQA 2PZ1A 2DKQA 4KHBB 2J0JA 1UNRA 4HDQA 4K17A 1OY2A 1FGZA 2YS3A 2COAA 2BCJA 2CAYA 5EFXA 5J3QA 1I2HA 1DBHA 1LB1A 2D9WA 4NY0A 2VRWB 5LOPB 1W1DA 2IYBA 1GC6A 3UZTA 4HHVA 4Z2NA 5JHHA 4A5KA 4EMOA 3X23A 3P6AA 4NSWA 1TQZA 4K81A 4BBKA 2YT0A 1UNQA 4HAZB 3MDBC 1UEFA 1DDWA 5JLJB 3DXCA 4F7HA 3PEGA 1AWEA 1Y19B 4Z2MB 1U5EA 2D9XA 2LULA 4IFSA 3PVWA 3G9WA 3PG7A 2Z0PA 1NTVA 1X05A 3LJUX 3AU5A 5D3VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3T06 A;  5KCV A;  2RLO A;  3P7Z A;  4TYZ A;  2D9Z A;  3SV1 A;  2EC1 A;  3CIK A;  1GG3 A;  1WVH A;  1UNP A;  1MK7 B;  2RSG A;  1ZC3 B;  2XQN M;  3KZ1 A;  1MIX A;  1J19 A;  3RCP A;  2MWN B;  1EAZ A;  2LOZ A;  1WJ1 A;  2DYQ A;  2Y8G A;  2NZ8 B;  3F0W A;  4HAW B;  3TVV A;  1V88 A;  1U5F A;  5C16 A;  3A98 B;  2Z0O A;  1U5G A;  2FJL A;  1I7A A;  5KQ4 A;  3QBV B;  4HDO A;  4DX8 A;  1MPH A;  2Z0Q A;  1FHX A;  1EF1 A;  4DBB A;  4GMX B;  5LON B;  3TFM A;  3PSC A;  5D3Y A;  1U27 A;  2I5F A;  4KVG B;  2YT1 A;  3ULC A;  2LYD A;  1H10 A;  2D11 A;  1GC7 A;  3ZVR A;  2Y8F A;  3ODO A;  2QKL A;  1V89 A;  2YSZ A;  2H7D A;  1MKE A;  3IVF A;  2H7E A;  3GYP A;  4PNK A;  3F5R A;  1OQN A;  2MFQ A;  2DFK A;  2EJ8 A;  3ULB A;  1FAO A;  2CY4 A;  4MY6 A;  3KY9 A;  5J3Y A;  3FSS A;  4Y94 A;  2UVM A;  4F7U P;  1BWN A;  5L81 A;  3TW1 A;  1QC6 A;  2DHJ A;  2DHK A;  1PMS A;  3SYX A;  3GYO A;  2VKI A;  2COF A;  3PZD A;  4F7G A;  2UZR A;  1Z87 A;  4KAX B;  3O96 A;  1P5T A;  4ZRJ A;  2GJY A;  4TKN A;  4KHA A;  5KQ1 A;  1X11 A;  2D2Q A;  2GCL A;  2W2W A;  4K2P A;  2DTC A;  2L1C A;  3BIN A;  1W1H A;  1XKE A;  2J0M A;  3PVL A;  2COC A;  1P6S A;  2DKP A;  2G35 A;  2LOX A;  5D27 A;  4IAP A;  1MK9 B;  2R09 A;  2RVB B;  3HW2 B;  1X1G A;  4WVF B;  2P0H A;  2MKR A;  2LG1 A;  3SNH A;  2RNR B;  3KRX A;  3U7D A;  1DDV A;  1DDM A;  2Y7B A;  4MK0 A;  1XOD A;  1Q67 A;  4HB0 B;  1SGH A;  4GMV A;  4L6E A;  3WYF B;  3SUZ A;  3MPX A;  2MDX A;  4A6K A;  3QWM A;  2I5C A;  2DLW A;  1XD4 A;  4YON A;  1V61 A;  3D8D A;  1Y5O A;  2AEH A;  3VIA A;  2I1K A;  4YL8 A;  5JHG A;  5DIF B;  1UPQ A;  3KSY A;  1SHC A;  1X1F A;  3KRW A;  3D8E A;  1BAK A;  1V5U A;  4HAU B;  4A6F A;  4HB3 B;  2DX1 A;  2N0Y A;  2P0D A;  1NU2 A;  1WGU A;  1TXD A;  2DX5 A;  2AL6 A;  4H8S A;  4HAT B;  1ZSQ A;  5HE2 A;  4GXB A;  3SO6 A;  2RGN B;  4XWX A;  1P3R A;  5DI9 B;  2VSZ A;  1XCG A;  1M7R A;  2GS0 A;  3BJI A;  2DYN A;  2HTH B;  1X86 A;  5DH9 B;  1MAI A;  1RRP B;  4C0A A;  4ZRI A;  5DHA B;  1WG7 A;  1OMW A;  1M7E A;  4EJN A;  4MT7 A;  2M38 A;  5CLQ B;  1W1G A;  4WJ7 A;  2OQB A;  2ZPY A;  3A8P A;  2D9V A;  2LKO A;  1WI1 A;  1U2B A;  2DA0 A;  4KHO A;  3ML4 A;  5HE0 A;  1QQG A;  2J59 M;  4A6F B;  3ZDT A;  1E5W A;  1WJM A;  2ROZ B;  4K2O A;  3AJ4 A;  1N3H A;  2YVC A;  2ELA A;  1V5M A;  2DHI A;  1UPR A;  1PLS A;  1DYN A;  3QIJ A;  1FOE A;  1K5D B;  2R0D A;  3CXB B;  4B6H A;  2ELB A;  2CRF A;  1FHO A;  3OAN A;  1XX0 A;  5D3W A;  3WA0 A;  2KCJ A;  4WSF A;  3HK0 A;  4HAY B;  1XR0 B;  1DRO A;  2Q13 A;  2YS1 A;  1RJ2 A;  2COD A;  3VOQ A;  2V76 A;  3PVU A;  5HE3 A;  3V5W A;  4HAV B;  5HE1 A;  4EKU A;  3DXE A;  1ZC4 B;  2OTX A;  1BTN A;  4ZRK A;  5C79 A;  3A8Q A;  2I1J A;  2ADZ A;  2N23 A;  5C5B A;  1EGX A;  2M14 A;  1J0W A;  4IOY X;  1ZVR A;  2DN6 A;  2X18 A;  1PFJ A;  1AQC A;  2P8V A;  2K2J A;  3M1I B;  1ISN A;  2E2X A;  2EMS A;  2KUP A;  4CHJ A;  1IRS A;  2W2X C;  2UZS A;  1FB8 A;  5FI0 A;  1ZM0 A;  3HQC A;  2HE7 A;  2QKM A;  1BTK A;  2RUK B;  4HAX B;  4GZU A;  4D0N B;  2W2X D;  2KGX B;  2GCJ A;  1MIZ B;  5CLL B;  3TCA A;  2K00 A;  3ODX A;  3NSU A;  3U8Z A;  4CYE A;  1FHW A;  1NTY A;  2CY5 A;  4GPT B;  1EVH A;  1NI2 A;  2L2I A;  3AU4 A;  1K5G B;  3ODW A;  2JP2 A;  1FGY A;  2D10 A;  1U5D A;  2NMB A;  3FEH A;  1V5P A;  4HB2 B;  3D8F A;  2P0F A;  2D4Q A;  3FM8 C;  2EMT A;  4P7I A;  2YRY A;  2D9Y A;  2J0K A;  5C5B B;  2YS5 A;  5DHF B;  1LW3 A;  3PP2 A;  5J3T A;  1B55 A;  3N7C A;  2YF0 A;  1H4R A;  1KZ7 A;  4PQ0 A;  4DX9 0;  2K2U A;  5FI1 A;  2IFS A;  1U29 A;  2ROV A;  4HB4 B;  4CHM A;  5GOW B;  1KI1 B;  1KZG A;  4DXA B;  1TJ6 A;  4A6H A;  5JP4 A;  3DXD A;  5C6R A;  4GN1 A;  5D3X A;  3TO1 A;  1WGQ A;  2PZ1 A;  2DKQ A;  4KHB B;  2J0J A;  1UNR A;  4HDQ A;  4K17 A;  1OY2 A;  1FGZ A;  2YS3 A;  2COA A;  2BCJ A;  2CAY A;  5EFX A;  5J3Q A;  1I2H A;  1DBH A;  1LB1 A;  2D9W A;  4NY0 A;  2VRW B;  5LOP B;  1W1D A;  2IYB A;  1GC6 A;  3UZT A;  4HHV A;  4Z2N A;  5JHH A;  4A5K A;  4EMO A;  3X23 A;  3P6A A;  4NSW A;  1TQZ A;  4K81 A;  4BBK A;  2YT0 A;  1UNQ A;  4HAZ B;  3MDB C;  1UEF A;  1DDW A;  5JLJ B;  3DXC A;  4F7H A;  3PEG A;  1AWE A;  1Y19 B;  4Z2M B;  1U5E A;  2D9X A;  2LUL A;  4IFS A;  3PVW A;  3G9W A;  3PG7 A;  2Z0P A;  1NTV A;  1X05 A;  3LJU X;  3AU5 A;  5D3V A; 
#chains in the Genus database with same CATH topology
 3T06 A;  5KCV A;  2RLO A;  3P7Z A;  4TYZ A;  2D9Z A;  3SV1 A;  2EC1 A;  3CIK A;  1GG3 A;  1WVH A;  3A58 A;  1UNP A;  2KIG A;  1MK7 B;  2RSG A;  1ZC3 B;  2XQN M;  3KZ1 A;  1MIX A;  1J19 A;  3RCP A;  2MWN B;  2Z13 A;  1EAZ A;  2K8E A;  2LOZ A;  1WJ1 A;  2DYQ A;  2Y8G A;  2NZ8 B;  3F0W A;  4HAW B;  3TVV A;  1V88 A;  1U5F A;  2GUM A;  5C16 A;  3A98 B;  2Z0O A;  1U5G A;  2FJL A;  1I7A A;  5KQ4 A;  3QBV B;  4HDO A;  4DX8 A;  1MPH A;  2Z0Q A;  1FHX A;  1EF1 A;  4DBB A;  4GMX B;  5LON B;  3TFM A;  3NW8 A;  3PSC A;  5D3Y A;  1U27 A;  2I5F A;  4KVG B;  2YT1 A;  3ULC A;  2LYD A;  1H10 A;  2D11 A;  1GC7 A;  4GNK B;  3ZVR A;  2Y8F A;  3ODO A;  2QKL A;  1V89 A;  2YSZ A;  2H7D A;  1MKE A;  3IVF A;  2H7E A;  4QXA B;  3GYP A;  4PNK A;  3F5R A;  1OQN A;  2MFQ A;  2DFK A;  2EJ8 A;  3ULB A;  1FAO A;  2CY4 A;  4MY6 A;  3KY9 A;  5J3Y A;  3FSS A;  4Y94 A;  2UVM A;  4F7U P;  1BWN A;  5L81 A;  4L1R A;  3TW1 A;  1QC6 A;  2DHJ A;  2DHK A;  1PMS A;  3SYX A;  3GYO A;  2VKI A;  2COF A;  3B77 A;  3HSA A;  3PZD A;  4F7G A;  2UZR A;  1Z87 A;  4KAX B;  3O96 A;  1P5T A;  4ZRJ A;  4D6W A;  2GJY A;  4TKN A;  4KHA A;  5KQ1 A;  1X11 A;  2D2Q A;  2GCL A;  2W2W A;  4K2P A;  2DTC A;  2L1C A;  3BIN A;  2Z4D A;  1W1H A;  1XKE A;  2J0M A;  3PVL A;  2COC A;  1P6S A;  2DKP A;  2G35 A;  2LOX A;  5D27 A;  4IAP A;  1MK9 B;  2R09 A;  2RVB B;  3HW2 B;  1X1G A;  4WVF B;  4DIX A;  2P0H A;  2MKR A;  2LG1 A;  3SNH A;  2RNR B;  3KRX A;  3U7D A;  1DDV A;  1DDM A;  2Y7B A;  4MK0 A;  1XOD A;  1Q67 A;  4HB0 B;  1SGH A;  4GMV A;  5IRS A;  4L6E A;  3WYF B;  3SUZ A;  4QJ4 B;  3MPX A;  2MDX A;  4A6K A;  3QWM A;  2I5C A;  2DLW A;  1XD4 A;  4YON A;  1V61 A;  3D8D A;  1Y5O A;  2Z59 A;  2AEH A;  3VIA A;  2I1K A;  4YL8 A;  5JHG A;  5DIF B;  1UPQ A;  3KSY A;  1SHC A;  1X1F A;  3KRW A;  3D8E A;  1BAK A;  1V5U A;  4HAU B;  4A6F A;  4HB3 B;  2DX1 A;  2K49 A;  4QJ3 B;  1MI1 A;  2N0Y A;  2P0D A;  1NU2 A;  1WGU A;  1TXD A;  4KHB A;  2DX5 A;  2AL6 A;  4H8S A;  4HAT B;  1ZSQ A;  5HE2 A;  4GXB A;  3SO6 A;  2RGN B;  4XWX A;  1P3R A;  5DI9 B;  2VSZ A;  1XCG A;  1M7R A;  2GS0 A;  3BJI A;  2DYN A;  2HTH B;  1X86 A;  5DH9 B;  1MAI A;  1RRP B;  4GOU A;  4ZRI A;  4C0A A;  5DHA B;  1WG7 A;  1OMW A;  1M7E A;  4EJN A;  4CSQ A;  4MT7 A;  4HSI A;  2M38 A;  5CLQ B;  1W1G A;  4WJ7 A;  2Z14 A;  2OQB A;  2ZPY A;  2KIE A;  3A8P A;  1ZYI A;  2D9V A;  2LKO A;  1WI1 A;  5I2M A;  5LG4 B;  1U2B A;  2DA0 A;  4KHO A;  3ML4 A;  5HE0 A;  1QQG A;  2J59 M;  4A6F B;  3ZDT A;  1E5W A;  1WJM A;  2ROZ B;  4K2O A;  3AJ4 A;  1N3H A;  2YVC A;  2ELA A;  1V5M A;  2DHI A;  1UPR A;  1PLS A;  1DYN A;  3QIJ A;  1FOE A;  1K5D B;  4QJ5 B;  2R0D A;  3FVC A;  3CXB B;  4B6H A;  2ELB A;  2CRF A;  1FHO A;  3OAN A;  1XX0 A;  5D3W A;  3WA0 A;  1T77 A;  2KCJ A;  4WSF A;  4OSN A;  3HK0 A;  4HAY B;  1XR0 B;  1DRO A;  2Q13 A;  2YS1 A;  1RJ2 A;  2COD A;  3HIE A;  3VOQ A;  2V76 A;  3PVU A;  5HE3 A;  3V5W A;  4HAV B;  5HE1 A;  4EKU A;  3DXE A;  1ZC4 B;  2OTX A;  1BTN A;  4ZRK A;  5C79 A;  2R2Y A;  3A8Q A;  2I1J A;  2ADZ A;  2N23 A;  5C5B A;  1EGX A;  2M14 A;  1J0W A;  4IOY X;  1ZVR A;  2DN6 A;  2X18 A;  1PFJ A;  1AQC A;  2P8V A;  2K2J A;  3M1I B;  1ISN A;  2E2X A;  2EMS A;  2KUP A;  4CHJ A;  1IRS A;  2W2X C;  2UZS A;  1FB8 A;  5FI0 A;  1ZM0 A;  3HQC A;  2HE7 A;  2QKM A;  2KR0 A;  1BTK A;  2RUK B;  4HAX B;  4GZU A;  4D0N B;  2W2X D;  2KGX B;  2GCJ A;  1MIZ B;  5CLL B;  3TCA A;  2K00 A;  3ODX A;  3NSU A;  3U8Z A;  4CYE A;  1FHW A;  1NTY A;  2CY5 A;  4GPT B;  1EVH A;  1NI2 A;  2L2I A;  3AU4 A;  1K5G B;  3ODW A;  5I2S A;  3DCX A;  2JP2 A;  2NBV A;  1FGY A;  2D10 A;  1U5D A;  2NMB A;  3FEH A;  3NWD A;  1V5P A;  4HB2 B;  3D8F A;  2P0F A;  5M4Y B;  2D4Q A;  3FM8 C;  2EMT A;  4P7I A;  2YRY A;  2D9Y A;  2J0K A;  5C5B B;  2YS5 A;  5DHF B;  1LW3 A;  3PP2 A;  5J3T A;  1B55 A;  3N7C A;  2FJU B;  2YF0 A;  1H4R A;  1KZ7 A;  4PQ0 A;  4DX9 0;  2K2U A;  5FI1 A;  2IFS A;  3NWF A;  1U29 A;  2ROV A;  4HB4 B;  4CHM A;  5GOW B;  1KI1 B;  1KZG A;  4DXA B;  1TJ6 A;  2KUQ A;  3OHM B;  4A6H A;  5JP4 A;  3DXD A;  5C6R A;  4GN1 A;  5D3X A;  3TO1 A;  1WGQ A;  2PZ1 A;  2DKQ A;  4KHB B;  2J0J A;  1UNR A;  4HDQ A;  3NWA A;  4K17 A;  1OY2 A;  1FGZ A;  2YS3 A;  2COA A;  2BCJ A;  2CAY A;  5EFX A;  5J3Q A;  1I2H A;  1DBH A;  1LB1 A;  2D9W A;  4NY0 A;  2VRW B;  5LOP B;  1W1D A;  2IYB A;  1GC6 A;  3UZT A;  4HHV A;  4Z2N A;  5JHH A;  4A5K A;  4EMO A;  3X23 A;  3P6A A;  4NSW A;  1TQZ A;  4K81 A;  4BBK A;  2YT0 A;  1UNQ A;  2RRF A;  4HAZ B;  3MDB C;  1UEF A;  1DDW A;  5JLJ B;  3DXC A;  4F7H A;  3PEG A;  1AWE A;  1Y19 B;  4Z2M B;  1U5E A;  2YT2 A;  2D9X A;  2LUL A;  3U12 A;  4IFS A;  4OT1 A;  3PVW A;  3G9W A;  3PG7 A;  2ZKM X;  2Z0P A;  1NTV A;  1X05 A;  3LJU X;  3AU5 A;  5D3V A; 
#chains in the Genus database with same CATH homology
 3T06 A;  5KCV A;  2RLO A;  3P7Z A;  4TYZ A;  2D9Z A;  3SV1 A;  2EC1 A;  3CIK A;  1GG3 A;  1WVH A;  1UNP A;  1MK7 B;  2RSG A;  1ZC3 B;  2XQN M;  3KZ1 A;  1MIX A;  1J19 A;  3RCP A;  2MWN B;  1EAZ A;  2LOZ A;  1WJ1 A;  2DYQ A;  2Y8G A;  2NZ8 B;  3F0W A;  4HAW B;  3TVV A;  1V88 A;  1U5F A;  5C16 A;  3A98 B;  2Z0O A;  1U5G A;  2FJL A;  1I7A A;  5KQ4 A;  3QBV B;  4HDO A;  4DX8 A;  1MPH A;  2Z0Q A;  1FHX A;  1EF1 A;  4DBB A;  4GMX B;  5LON B;  3TFM A;  3PSC A;  5D3Y A;  1U27 A;  2I5F A;  4KVG B;  2YT1 A;  3ULC A;  2LYD A;  1H10 A;  2D11 A;  1GC7 A;  3ZVR A;  2Y8F A;  3ODO A;  2QKL A;  1V89 A;  2YSZ A;  2H7D A;  1MKE A;  3IVF A;  2H7E A;  3GYP A;  4PNK A;  3F5R A;  1OQN A;  2MFQ A;  2DFK A;  2EJ8 A;  3ULB A;  1FAO A;  2CY4 A;  4MY6 A;  3KY9 A;  5J3Y A;  3FSS A;  4Y94 A;  2UVM A;  4F7U P;  1BWN A;  5L81 A;  3TW1 A;  1QC6 A;  2DHJ A;  2DHK A;  1PMS A;  3SYX A;  3GYO A;  2VKI A;  2COF A;  3PZD A;  4F7G A;  2UZR A;  1Z87 A;  4KAX B;  3O96 A;  1P5T A;  4ZRJ A;  2GJY A;  4TKN A;  4KHA A;  5KQ1 A;  1X11 A;  2D2Q A;  2GCL A;  2W2W A;  4K2P A;  2DTC A;  2L1C A;  3BIN A;  1W1H A;  1XKE A;  2J0M A;  3PVL A;  2COC A;  1P6S A;  2DKP A;  2G35 A;  2LOX A;  5D27 A;  4IAP A;  1MK9 B;  2R09 A;  2RVB B;  3HW2 B;  1X1G A;  4WVF B;  2P0H A;  2MKR A;  2LG1 A;  3SNH A;  2RNR B;  3KRX A;  3U7D A;  1DDV A;  1DDM A;  2Y7B A;  4MK0 A;  1XOD A;  1Q67 A;  4HB0 B;  1SGH A;  4GMV A;  4L6E A;  3WYF B;  3SUZ A;  3MPX A;  2MDX A;  4A6K A;  3QWM A;  2I5C A;  2DLW A;  1XD4 A;  4YON A;  1V61 A;  3D8D A;  1Y5O A;  2AEH A;  3VIA A;  2I1K A;  4YL8 A;  5JHG A;  5DIF B;  1UPQ A;  3KSY A;  1SHC A;  1X1F A;  3KRW A;  3D8E A;  1BAK A;  1V5U A;  4HAU B;  4A6F A;  4HB3 B;  2DX1 A;  2N0Y A;  2P0D A;  1NU2 A;  1WGU A;  1TXD A;  2DX5 A;  2AL6 A;  4H8S A;  4HAT B;  1ZSQ A;  5HE2 A;  4GXB A;  3SO6 A;  2RGN B;  4XWX A;  1P3R A;  5DI9 B;  2VSZ A;  1XCG A;  1M7R A;  2GS0 A;  3BJI A;  2DYN A;  2HTH B;  1X86 A;  5DH9 B;  1MAI A;  1RRP B;  4C0A A;  4ZRI A;  5DHA B;  1WG7 A;  1OMW A;  1M7E A;  4EJN A;  4MT7 A;  2M38 A;  5CLQ B;  1W1G A;  4WJ7 A;  2OQB A;  2ZPY A;  3A8P A;  2D9V A;  2LKO A;  1WI1 A;  1U2B A;  2DA0 A;  4KHO A;  3ML4 A;  5HE0 A;  1QQG A;  2J59 M;  4A6F B;  3ZDT A;  1E5W A;  1WJM A;  2ROZ B;  4K2O A;  3AJ4 A;  1N3H A;  2YVC A;  2ELA A;  1V5M A;  2DHI A;  1UPR A;  1PLS A;  1DYN A;  3QIJ A;  1FOE A;  1K5D B;  2R0D A;  3CXB B;  4B6H A;  2ELB A;  2CRF A;  1FHO A;  3OAN A;  1XX0 A;  5D3W A;  3WA0 A;  2KCJ A;  4WSF A;  3HK0 A;  4HAY B;  1XR0 B;  1DRO A;  2Q13 A;  2YS1 A;  1RJ2 A;  2COD A;  3VOQ A;  2V76 A;  3PVU A;  5HE3 A;  3V5W A;  4HAV B;  5HE1 A;  4EKU A;  3DXE A;  1ZC4 B;  2OTX A;  1BTN A;  4ZRK A;  5C79 A;  3A8Q A;  2I1J A;  2ADZ A;  2N23 A;  5C5B A;  1EGX A;  2M14 A;  1J0W A;  4IOY X;  1ZVR A;  2DN6 A;  2X18 A;  1PFJ A;  1AQC A;  2P8V A;  2K2J A;  3M1I B;  1ISN A;  2E2X A;  2EMS A;  2KUP A;  4CHJ A;  1IRS A;  2W2X C;  2UZS A;  1FB8 A;  5FI0 A;  1ZM0 A;  3HQC A;  2HE7 A;  2QKM A;  1BTK A;  2RUK B;  4HAX B;  4GZU A;  4D0N B;  2W2X D;  2KGX B;  2GCJ A;  1MIZ B;  5CLL B;  3TCA A;  2K00 A;  3ODX A;  3NSU A;  3U8Z A;  4CYE A;  1FHW A;  1NTY A;  2CY5 A;  4GPT B;  1EVH A;  1NI2 A;  2L2I A;  3AU4 A;  1K5G B;  3ODW A;  2JP2 A;  1FGY A;  2D10 A;  1U5D A;  2NMB A;  3FEH A;  1V5P A;  4HB2 B;  3D8F A;  2P0F A;  2D4Q A;  3FM8 C;  2EMT A;  4P7I A;  2YRY A;  2D9Y A;  2J0K A;  5C5B B;  2YS5 A;  5DHF B;  1LW3 A;  3PP2 A;  5J3T A;  1B55 A;  3N7C A;  2YF0 A;  1H4R A;  1KZ7 A;  4PQ0 A;  4DX9 0;  2K2U A;  5FI1 A;  2IFS A;  1U29 A;  2ROV A;  4HB4 B;  4CHM A;  5GOW B;  1KI1 B;  1KZG A;  4DXA B;  1TJ6 A;  4A6H A;  5JP4 A;  3DXD A;  5C6R A;  4GN1 A;  5D3X A;  3TO1 A;  1WGQ A;  2PZ1 A;  2DKQ A;  4KHB B;  2J0J A;  1UNR A;  4HDQ A;  4K17 A;  1OY2 A;  1FGZ A;  2YS3 A;  2COA A;  2BCJ A;  2CAY A;  5EFX A;  5J3Q A;  1I2H A;  1DBH A;  1LB1 A;  2D9W A;  4NY0 A;  2VRW B;  5LOP B;  1W1D A;  2IYB A;  1GC6 A;  3UZT A;  4HHV A;  4Z2N A;  5JHH A;  4A5K A;  4EMO A;  3X23 A;  3P6A A;  4NSW A;  1TQZ A;  4K81 A;  4BBK A;  2YT0 A;  1UNQ A;  4HAZ B;  3MDB C;  1UEF A;  1DDW A;  5JLJ B;  3DXC A;  4F7H A;  3PEG A;  1AWE A;  1Y19 B;  4Z2M B;  1U5E A;  2D9X A;  2LUL A;  4IFS A;  3PVW A;  3G9W A;  3PG7 A;  2Z0P A;  1NTV A;  1X05 A;  3LJU X;  3AU5 A;  5D3V A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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