1QQGA

Crystal structure of the ph-ptb targeting region of irs-1
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
251
structure length
207
Chain Sequence
DVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAPKRSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHAFKEVWQVILKPKGLGQTKNLIGIYRLCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQVDDSVVAQNMHETILEAMRAMSD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the pleckstrin homology-phosphotyrosine binding (PH-PTB) targeting region of insulin receptor substrate 1.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Signal transduction
molecule keywords INSULIN RECEPTOR SUBSTRATE 1
total genus 51
structure length 207
sequence length 251
chains with identical sequence B
ec nomenclature
pdb deposition date 1999-06-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00169 PH PH domain
A PF02174 IRS PTB domain (IRS-1 type)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 1qqgA02
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 1qqgA01
3PEGA 3QBVB 2HTHB 2ELBA 1UEFA 1AWEA 2W2XC 2RGNB 3TFMA 1BAKA 1SGHA 2LG1A 4CYEA 1Y5OA 2YRYA 5JHGA 2YT0A 4A5KA 1V5UA 3DXCA 2ROZB 1BTKA 3CXBB 3KRWA 3SNHA 4GMXB 3U7DA 4CHJA 1MPHA 1V89A 2DX1A 2DKQA 4GMVA 5HE0A 3G9WA 1V5MA 4KAXB 5D27A 5J3TA 3KSYA 1MKEA 1DDWA 5D3VA 1J19A 2YT1A 1M7EA 4HAXB 3P7ZA 1UPQA 5CLQB 1FOEA 5JLJB 2L1CA 2IFSA 2Q13A 2NZ8B 1V61A 3SV1A 4F7HA 2KGXB 3A8PA 3V5WA 2DHKA 2V76A 2Z0PA 2K2JA 2OQBA 4HAYB 1Q67A 2ROVA 2H7DA 5J3QA 4HDQA 4HB3B 5KCVA 3ODWA 4IFSA 3HQCA 5DHFB 4A6KA 4ZRKA 2D9ZA 1ZVRA 4KHOA 4D0NB 1U5EA 1EGXA 4TKNA 3AJ4A 2DYQA 2I5FA 4PQ0A 1EF1A 1P3RA 3FEHA 2QKMA 1DROA 2VKIA 1U27A 1WJMA 1I7AA 2QKLA 2DTCA 4DX8A 5D3YA 3ULCA 3KRXA 2LULA 1V5PA 1AQCA 1NI2A 3SUZA 4ZRJA 3TW1A 4C0AA 3AU4A 1WI1A 5C6RA 2GS0A 4IOYX 1DDMA 3PP2A 2P0FA 1KZGA 2DFKA 2AL6A 1P6SA 4GZUA 4HAUB 2YS5A 3PVLA 1Z87A 1XODA 2J0MA 2OTXA 1U5GA 1GC6A 4KVGB 4H8SA 4CHMA 5L81A 1X11A 3QIJA 3WA0A 1WGQA 3D8EA 4ZRIA 4HDOA 4NSWA 2D10A 1EVHA 1X1GA 3N7CA 2H7EA 3KZ1A 2DA0A 5GOWB 4B6HA 1KI1B 1U2BA 2LKOA 4XWXA 5KQ1A 1H4RA 1FAOA 3ZVRA 4GXBA 4DBBA 2RVBB 3CIKA 2M38A 2EJ8A 2I5CA 4EMOA 1FHXA 2DLWA 4HATB 3TCAA 3F0WA 2COCA 2K2UA 3QWMA 2MDXA 3ULBA 1BWNA 2ZPYA 3MPXA 2ELAA 3SO6A 3MDBC 4YL8A 2YS1A 5D3WA 4HB4B 3P6AA 2CAYA 1DBHA 5C79A 2Z0OA 3UZTA 5EFXA 1V88A 4A6HA 1XCGA 1K5GB 2ADZA 4Z2NA 2Y8FA 2Z0QA 1RJ2A 2M14A 3NSUA 2I1JA 1H10A 4BBKA 1DDVA 3F5RA 1FHOA 5DIFB 5FI1A 3GYOA 4HAZB 2D9YA 4IAPA 3PVUA 3T06A 4PNKA 3PZDA 2D9WA 4Y94A 1K5DB 5C5BB 1MIXA 2I1KA 2DHJA 1WG7A 2GCLA 2R0DA 5DI9B 2CRFA 1TQZA 1SHCA 5DH9B 2DX5A 4WJ7A 1UNRA 4EKUA 3FSSA 2LOZA 1N3HA 4K17A 2R09A 3A8QA 5JHHA 1EAZA 1M7RA 1ISNA 2N0YA 3BINA 3VIAA 5HE2A 4Z2MB 1W1HA 1ZC4B 1W1DA 2VRWB 2YVCA 1P5TA 1XX0A 1FB8A 2AEHA 2J0KA 2MWNB 3ZDTA 5C16A 3ML4A 4KHAA 4DX90 2YSZA 5HE1A 2MKRA 1FGYA 4HHVA 2JP2A 2K00A 3PG7A 4KHBB 1Y19B 1OY2A 2DKPA 2L2IA 2Y7BA 2KCJA 2NMBA 2PZ1A 4F7GA 2CY5A 3A98B 1NTVA 2RLOA 2LOXA 1U5FA 2D9XA 4HAVB 3DXEA 2IYBA 1W1GA 4MY6A 2D9VA 2GJYA 1MIZB 5LOPB 1X1FA 5KQ4A 2DN6A 2Y8GA 5CLLB 4EJNA 3PVWA 2W2XD 4K81A 2UZSA 1OMWA 2J59M 5FI0A 4YONA 1WVHA 2P8VA 1FGZA 3HW2B 1KZ7A 2EMSA 1UPRA 3IVFA 2GCJA 4MK0A 3WYFB 3HK0A 1GG3A 4A6FA 1B55A 2EC1A 2RUKB 1WGUA 4P7IA 2G35A 3U8ZA 1RRPB 5LONB 1IRSA 2MFQA 3ODXA 3AU5A 3O96A 2COFA 4HB2B 2XQNM 5C5BA 1DYNA 2D2QA 5D3XA 1ZM0A 3ODOA 4F7UP 1I2HA 1MAIA 1LB1A 2X18A 1WJ1A 1OQNA 3D8FA 1MK9B 1LW3A 5J3YA 2CY4A 4MT7A 2UZRA 2YS3A 2N23A 2E2XA 1QC6A 1XKEA 1PFJA 1UNPA 2P0HA 2HE7A 2BCJA 1X86A 3TO1A 2CODA 3KY9A 1MK7B 3VOQA 4DXAB 1PMSA 3LJUX 1UNQA 5DHAB 2COAA 4TYZA 4L6EA 5JP4A 3PSCA 1NTYA 3DXDA 1ZC3B 2P0DA 2RNRB 3SYXA 5HE3A 3BJIA 4WSFA 3TVVA 2VSZA 4HAWB 2RSGA 1XD4A 2DHIA 2D11A 4WVFB 2KUPA 1J0WA 3X23A 2EMTA 1ZSQA 3FM8C 2W2WA 1GC7A 1QQGA 1E5WA 1X05A 2UVMA 4K2OA 1U5DA 4NY0A 3GYPA 3D8DA 1BTNA 1U29A 4A6FB 3RCPA 3OANA 1XR0B 1TJ6A 2DYNA 1FHWA 4K2PA 1PLSA 4HB0B 2YF0A 2LYDA 2D4QA 2FJLA 3M1IB 4GPTB 1NU2A 1TXDA 2J0JA 4GN1A
chains in the Genus database with same CATH superfamily
3PEGA 3QBVB 2HTHB 2ELBA 1UEFA 1AWEA 2W2XC 2RGNB 3TFMA 1BAKA 1SGHA 2LG1A 4CYEA 1Y5OA 2YRYA 3NWDA 2Z13A 4OSNA 5JHGA 2YT0A 4A5KA 1V5UA 3DXCA 2ROZB 1BTKA 3CXBB 3KRWA 3SNHA 4GMXB 3U7DA 2KIEA 4CHJA 1MPHA 1V89A 2DX1A 2DKQA 4GMVA 5HE0A 3G9WA 1V5MA 4KAXB 5D27A 5J3TA 3KSYA 1MKEA 1DDWA 5D3VA 1J19A 2YT1A 1M7EA 4HAXB 3P7ZA 1UPQA 5CLQB 1FOEA 5JLJB 3FVCA 2L1CA 2IFSA 2Q13A 2NZ8B 1V61A 3SV1A 4F7HA 2KGXB 3A8PA 3V5WA 2DHKA 2V76A 2Z0PA 2K2JA 2OQBA 4HAYB 1Q67A 2ROVA 2H7DA 2Z14A 5J3QA 4HDQA 4HB3B 5KCVA 3ODWA 4IFSA 3B77A 3HQCA 5DHFB 4A6KA 4ZRKA 2D9ZA 1ZVRA 4KHOA 4D0NB 1U5EA 1EGXA 4TKNA 3AJ4A 2DYQA 2I5FA 4PQ0A 1EF1A 1P3RA 3FEHA 2QKMA 1DROA 4D6WA 2VKIA 1U27A 1WJMA 1I7AA 2QKLA 2DTCA 4DX8A 5D3YA 3ULCA 3KRXA 2LULA 4QJ5B 1V5PA 1AQCA 1NI2A 3SUZA 4ZRJA 3TW1A 4C0AA 3AU4A 1WI1A 5C6RA 2GS0A 4IOYX 1DDMA 5LG4B 3PP2A 2KIGA 2P0FA 1KZGA 2DFKA 2AL6A 1P6SA 4GZUA 4HAUB 2YS5A 3PVLA 1Z87A 1XODA 4GNKB 2J0MA 2OTXA 1U5GA 1GC6A 4KVGB 4H8SA 2KR0A 4CHMA 5L81A 3HSAA 1X11A 3QIJA 3WA0A 1WGQA 2ZKMX 3D8EA 4ZRIA 4HDOA 4NSWA 2D10A 1EVHA 5I2MA 1X1GA 3N7CA 2H7EA 3KZ1A 5IRSA 2DA0A 5GOWB 4B6HA 1KI1B 1U2BA 2LKOA 4XWXA 5KQ1A 1H4RA 1FAOA 3ZVRA 4GXBA 4DBBA 2RVBB 2KUQA 1T77A 2M38A 3CIKA 2EJ8A 2I5CA 4EMOA 1FHXA 2DLWA 4HATB 3TCAA 3F0WA 2COCA 4HSIA 2K2UA 3QWMA 2MDXA 3ULBA 1BWNA 1MI1A 2ZPYA 4KHBA 3MPXA 2ELAA 4DIXA 3SO6A 3MDBC 4YL8A 2YS1A 5D3WA 4HB4B 3P6AA 2CAYA 1DBHA 5C79A 2Z0OA 2K49A 3UZTA 5EFXA 1V88A 4L1RA 4A6HA 1XCGA 1K5GB 2ADZA 4Z2NA 2Y8FA 2Z0QA 1RJ2A 2M14A 3NSUA 2I1JA 1H10A 4BBKA 1DDVA 3F5RA 1FHOA 5DIFB 5FI1A 3GYOA 4HAZB 2D9YA 2FJUB 4IAPA 3PVUA 3T06A 4PNKA 3PZDA 2D9WA 4Y94A 1K5DB 5C5BB 1MIXA 2I1KA 2DHJA 1WG7A 2GCLA 2R0DA 5DI9B 2CRFA 1TQZA 1SHCA 2R2YA 5DH9B 2DX5A 4WJ7A 4GOUA 1UNRA 4EKUA 3FSSA 2LOZA 1N3HA 4K17A 2R09A 3A8QA 5JHHA 1EAZA 1M7RA 1ISNA 2N0YA 3NW8A 3BINA 5M4YB 3VIAA 3NWAA 5HE2A 4Z2MB 1W1HA 1ZC4B 1W1DA 2VRWB 2YVCA 1P5TA 1XX0A 1FB8A 2K8EA 2AEHA 2J0KA 2MWNB 3ZDTA 5C16A 3ML4A 4KHAA 4DX90 2YSZA 5HE1A 2MKRA 1FGYA 4HHVA 2JP2A 2K00A 3PG7A 4KHBB 1Y19B 1OY2A 2DKPA 2L2IA 1ZYIA 2Y7BA 2KCJA 2NMBA 2PZ1A 4F7GA 2CY5A 3A98B 1NTVA 2RLOA 2LOXA 1U5FA 2D9XA 4HAVB 4GN1A 3DXEA 2IYBA 1W1GA 4MY6A 2D9VA 4QJ4B 2GJYA 1MIZB 5LOPB 1X1FA 4QXAB 5KQ4A 2DN6A 2Y8GA 5CLLB 4EJNA 3PVWA 2W2XD 4K81A 2UZSA 1OMWA 2J59M 5FI0A 4YONA 1WVHA 2P8VA 2GUMA 1FGZA 3HIEA 3HW2B 1KZ7A 2EMSA 1UPRA 3IVFA 2GCJA 4MK0A 3WYFB 3HK0A 1GG3A 4A6FA 1B55A 2EC1A 2RUKB 1WGUA 4P7IA 2G35A 3U8ZA 1RRPB 5LONB 1IRSA 2MFQA 3ODXA 3AU5A 3O96A 2RRFA 2COFA 4HB2B 4CSQA 2XQNM 5C5BA 3OHMB 1DYNA 2D2QA 5D3XA 1ZM0A 3ODOA 4F7UP 1I2HA 1MAIA 1LB1A 2X18A 1WJ1A 3NWFA 1OQNA 3D8FA 1MK9B 1LW3A 2NBVA 5J3YA 5I2SA 2CY4A 4MT7A 2UZRA 2YS3A 2N23A 2E2XA 1QC6A 1XKEA 1PFJA 1UNPA 2P0HA 2HE7A 2BCJA 1X86A 3TO1A 2CODA 3KY9A 1MK7B 3VOQA 4DXAB 1PMSA 3LJUX 1UNQA 5DHAB 2COAA 4TYZA 4L6EA 5JP4A 3PSCA 2Z59A 1NTYA 3DXDA 1ZC3B 2P0DA 2RNRB 3SYXA 5HE3A 3BJIA 4WSFA 3TVVA 2VSZA 4HAWB 2YT2A 2RSGA 1XD4A 2DHIA 2D11A 4QJ3B 4WVFB 2KUPA 1J0WA 3X23A 2EMTA 3FM8C 2W2WA 1GC7A 1QQGA 1E5WA 3DCXA 2Z4DA 1X05A 2UVMA 4K2OA 3A58A 1U5DA 4NY0A 3GYPA 3D8DA 1BTNA 1U29A 4A6FB 3RCPA 3OANA 1XR0B 1TJ6A 2DYNA 1FHWA 4K2PA 1PLSA 4HB0B 4OT1A 2YF0A 2LYDA 2D4QA 2FJLA 3M1IB 4GPTB 1NU2A 1TXDA 2J0JA 3U12A 1ZSQA
chains in the Genus database with same CATH topology
3PEGA 3QBVB 2HTHB 2ELBA 1UEFA 1AWEA 2W2XC 2RGNB 3TFMA 1BAKA 1SGHA 2LG1A 4CYEA 1Y5OA 2YRYA 5JHGA 2YT0A 4A5KA 1V5UA 3DXCA 2ROZB 1BTKA 3CXBB 3KRWA 3SNHA 4GMXB 3U7DA 4CHJA 1MPHA 1V89A 2DX1A 2DKQA 4GMVA 5HE0A 3G9WA 1V5MA 4KAXB 5D27A 5J3TA 3KSYA 1MKEA 1DDWA 5D3VA 1J19A 2YT1A 1M7EA 4HAXB 3P7ZA 1UPQA 5CLQB 1FOEA 5JLJB 2L1CA 2IFSA 2Q13A 2NZ8B 1V61A 3SV1A 4F7HA 2KGXB 3A8PA 3V5WA 2DHKA 2V76A 2Z0PA 2K2JA 2OQBA 4HAYB 1Q67A 2ROVA 2H7DA 5J3QA 4HDQA 4HB3B 5KCVA 3ODWA 4IFSA 3HQCA 5DHFB 4A6KA 4ZRKA 2D9ZA 1ZVRA 4KHOA 4D0NB 1U5EA 1EGXA 4TKNA 3AJ4A 2DYQA 2I5FA 4PQ0A 1EF1A 1P3RA 3FEHA 2QKMA 1DROA 2VKIA 1U27A 1WJMA 1I7AA 2QKLA 2DTCA 4DX8A 5D3YA 3ULCA 3KRXA 2LULA 1V5PA 1AQCA 1NI2A 3SUZA 4ZRJA 3TW1A 4C0AA 3AU4A 1WI1A 5C6RA 2GS0A 4IOYX 1DDMA 3PP2A 2P0FA 1KZGA 2DFKA 2AL6A 1P6SA 4GZUA 4HAUB 2YS5A 3PVLA 1Z87A 1XODA 2J0MA 2OTXA 1U5GA 1GC6A 4KVGB 4H8SA 4CHMA 5L81A 1X11A 3QIJA 3WA0A 1WGQA 3D8EA 4ZRIA 4HDOA 4NSWA 2D10A 1EVHA 1X1GA 3N7CA 2H7EA 3KZ1A 2DA0A 5GOWB 4B6HA 1KI1B 1U2BA 2LKOA 4XWXA 5KQ1A 1H4RA 1FAOA 3ZVRA 4GXBA 4DBBA 2RVBB 3CIKA 2M38A 2EJ8A 2I5CA 4EMOA 1FHXA 2DLWA 4HATB 3TCAA 3F0WA 2COCA 2K2UA 3QWMA 2MDXA 3ULBA 1BWNA 2ZPYA 3MPXA 2ELAA 3SO6A 3MDBC 4YL8A 2YS1A 5D3WA 4HB4B 3P6AA 2CAYA 1DBHA 5C79A 2Z0OA 3UZTA 5EFXA 1V88A 4A6HA 1XCGA 1K5GB 2ADZA 4Z2NA 2Y8FA 2Z0QA 1RJ2A 2M14A 3NSUA 2I1JA 1H10A 4BBKA 1DDVA 3F5RA 1FHOA 5DIFB 5FI1A 3GYOA 4HAZB 2D9YA 4IAPA 3PVUA 3T06A 4PNKA 3PZDA 2D9WA 4Y94A 1K5DB 5C5BB 1MIXA 2I1KA 2DHJA 1WG7A 2GCLA 2R0DA 5DI9B 2CRFA 1TQZA 1SHCA 5DH9B 2DX5A 4WJ7A 1UNRA 4EKUA 3FSSA 2LOZA 1N3HA 4K17A 2R09A 3A8QA 5JHHA 1EAZA 1M7RA 1ISNA 2N0YA 3BINA 3VIAA 5HE2A 4Z2MB 1W1HA 1ZC4B 1W1DA 2VRWB 2YVCA 1P5TA 1XX0A 1FB8A 2AEHA 2J0KA 2MWNB 3ZDTA 5C16A 3ML4A 4KHAA 4DX90 2YSZA 5HE1A 2MKRA 1FGYA 4HHVA 2JP2A 2K00A 3PG7A 4KHBB 1Y19B 1OY2A 2DKPA 2L2IA 2Y7BA 2KCJA 2NMBA 2PZ1A 4F7GA 2CY5A 3A98B 1NTVA 2RLOA 2LOXA 1U5FA 2D9XA 4HAVB 3DXEA 2IYBA 1W1GA 4MY6A 2D9VA 2GJYA 1MIZB 5LOPB 1X1FA 5KQ4A 2DN6A 2Y8GA 5CLLB 4EJNA 3PVWA 2W2XD 4K81A 2UZSA 1OMWA 2J59M 5FI0A 4YONA 1WVHA 2P8VA 1FGZA 3HW2B 1KZ7A 2EMSA 1UPRA 3IVFA 2GCJA 4MK0A 3WYFB 3HK0A 1GG3A 4A6FA 1B55A 2EC1A 2RUKB 1WGUA 4P7IA 2G35A 3U8ZA 1RRPB 5LONB 1IRSA 2MFQA 3ODXA 3AU5A 3O96A 2COFA 4HB2B 2XQNM 5C5BA 1DYNA 2D2QA 5D3XA 1ZM0A 3ODOA 4F7UP 1I2HA 1MAIA 1LB1A 2X18A 1WJ1A 1OQNA 3D8FA 1MK9B 1LW3A 5J3YA 2CY4A 4MT7A 2UZRA 2YS3A 2N23A 2E2XA 1QC6A 1XKEA 1PFJA 1UNPA 2P0HA 2HE7A 2BCJA 1X86A 3TO1A 2CODA 3KY9A 1MK7B 3VOQA 4DXAB 1PMSA 3LJUX 1UNQA 5DHAB 2COAA 4TYZA 4L6EA 5JP4A 3PSCA 1NTYA 3DXDA 1ZC3B 2P0DA 2RNRB 3SYXA 5HE3A 3BJIA 4WSFA 3TVVA 2VSZA 4HAWB 2RSGA 1XD4A 2DHIA 2D11A 4WVFB 2KUPA 1J0WA 3X23A 2EMTA 1ZSQA 3FM8C 2W2WA 1GC7A 1QQGA 1E5WA 1X05A 2UVMA 4K2OA 1U5DA 4NY0A 3GYPA 3D8DA 1BTNA 1U29A 4A6FB 3RCPA 3OANA 1XR0B 1TJ6A 2DYNA 1FHWA 4K2PA 1PLSA 4HB0B 2YF0A 2LYDA 2D4QA 2FJLA 3M1IB 4GPTB 1NU2A 1TXDA 2J0JA 4GN1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PEG A;  3QBV B;  2HTH B;  2ELB A;  1UEF A;  1AWE A;  2W2X C;  2RGN B;  3TFM A;  1BAK A;  1SGH A;  2LG1 A;  4CYE A;  1Y5O A;  2YRY A;  5JHG A;  2YT0 A;  4A5K A;  1V5U A;  3DXC A;  2ROZ B;  1BTK A;  3CXB B;  3KRW A;  3SNH A;  4GMX B;  3U7D A;  4CHJ A;  1MPH A;  1V89 A;  2DX1 A;  2DKQ A;  4GMV A;  5HE0 A;  3G9W A;  1V5M A;  4KAX B;  5D27 A;  5J3T A;  3KSY A;  1MKE A;  1DDW A;  5D3V A;  1J19 A;  2YT1 A;  1M7E A;  4HAX B;  3P7Z A;  1UPQ A;  5CLQ B;  1FOE A;  5JLJ B;  2L1C A;  2IFS A;  2Q13 A;  2NZ8 B;  1V61 A;  3SV1 A;  4F7H A;  2KGX B;  3A8P A;  3V5W A;  2DHK A;  2V76 A;  2Z0P A;  2K2J A;  2OQB A;  4HAY B;  1Q67 A;  2ROV A;  2H7D A;  5J3Q A;  4HDQ A;  4HB3 B;  5KCV A;  3ODW A;  4IFS A;  3HQC A;  5DHF B;  4A6K A;  4ZRK A;  2D9Z A;  1ZVR A;  4KHO A;  4D0N B;  1U5E A;  1EGX A;  4TKN A;  3AJ4 A;  2DYQ A;  2I5F A;  4PQ0 A;  1EF1 A;  1P3R A;  3FEH A;  2QKM A;  1DRO A;  2VKI A;  1U27 A;  1WJM A;  1I7A A;  2QKL A;  2DTC A;  4DX8 A;  5D3Y A;  3ULC A;  3KRX A;  2LUL A;  1V5P A;  1AQC A;  1NI2 A;  3SUZ A;  4ZRJ A;  3TW1 A;  4C0A A;  3AU4 A;  1WI1 A;  5C6R A;  2GS0 A;  4IOY X;  1DDM A;  3PP2 A;  2P0F A;  1KZG A;  2DFK A;  2AL6 A;  1P6S A;  4GZU A;  4HAU B;  2YS5 A;  3PVL A;  1Z87 A;  1XOD A;  2J0M A;  2OTX A;  1U5G A;  1GC6 A;  4KVG B;  4H8S A;  4CHM A;  5L81 A;  1X11 A;  3QIJ A;  3WA0 A;  1WGQ A;  3D8E A;  4ZRI A;  4HDO A;  4NSW A;  2D10 A;  1EVH A;  1X1G A;  3N7C A;  2H7E A;  3KZ1 A;  2DA0 A;  5GOW B;  4B6H A;  1KI1 B;  1U2B A;  2LKO A;  4XWX A;  5KQ1 A;  1H4R A;  1FAO A;  3ZVR A;  4GXB A;  4DBB A;  2RVB B;  3CIK A;  2M38 A;  2EJ8 A;  2I5C A;  4EMO A;  1FHX A;  2DLW A;  4HAT B;  3TCA A;  3F0W A;  2COC A;  2K2U A;  3QWM A;  2MDX A;  3ULB A;  1BWN A;  2ZPY A;  3MPX A;  2ELA A;  3SO6 A;  3MDB C;  4YL8 A;  2YS1 A;  5D3W A;  4HB4 B;  3P6A A;  2CAY A;  1DBH A;  5C79 A;  2Z0O A;  3UZT A;  5EFX A;  1V88 A;  4A6H A;  1XCG A;  1K5G B;  2ADZ A;  4Z2N A;  2Y8F A;  2Z0Q A;  1RJ2 A;  2M14 A;  3NSU A;  2I1J A;  1H10 A;  4BBK A;  1DDV A;  3F5R A;  1FHO A;  5DIF B;  5FI1 A;  3GYO A;  4HAZ B;  2D9Y A;  4IAP A;  3PVU A;  3T06 A;  4PNK A;  3PZD A;  2D9W A;  4Y94 A;  1K5D B;  5C5B B;  1MIX A;  2I1K A;  2DHJ A;  1WG7 A;  2GCL A;  2R0D A;  5DI9 B;  2CRF A;  1TQZ A;  1SHC A;  5DH9 B;  2DX5 A;  4WJ7 A;  1UNR A;  4EKU A;  3FSS A;  2LOZ A;  1N3H A;  4K17 A;  2R09 A;  3A8Q A;  5JHH A;  1EAZ A;  1M7R A;  1ISN A;  2N0Y A;  3BIN A;  3VIA A;  5HE2 A;  4Z2M B;  1W1H A;  1ZC4 B;  1W1D A;  2VRW B;  2YVC A;  1P5T A;  1XX0 A;  1FB8 A;  2AEH A;  2J0K A;  2MWN B;  3ZDT A;  5C16 A;  3ML4 A;  4KHA A;  4DX9 0;  2YSZ A;  5HE1 A;  2MKR A;  1FGY A;  4HHV A;  2JP2 A;  2K00 A;  3PG7 A;  4KHB B;  1Y19 B;  1OY2 A;  2DKP A;  2L2I A;  2Y7B A;  2KCJ A;  2NMB A;  2PZ1 A;  4F7G A;  2CY5 A;  3A98 B;  1NTV A;  2RLO A;  2LOX A;  1U5F A;  2D9X A;  4HAV B;  3DXE A;  2IYB A;  1W1G A;  4MY6 A;  2D9V A;  2GJY A;  1MIZ B;  5LOP B;  1X1F A;  5KQ4 A;  2DN6 A;  2Y8G A;  5CLL B;  4EJN A;  3PVW A;  2W2X D;  4K81 A;  2UZS A;  1OMW A;  2J59 M;  5FI0 A;  4YON A;  1WVH A;  2P8V A;  1FGZ A;  3HW2 B;  1KZ7 A;  2EMS A;  1UPR A;  3IVF A;  2GCJ A;  4MK0 A;  3WYF B;  3HK0 A;  1GG3 A;  4A6F A;  1B55 A;  2EC1 A;  2RUK B;  1WGU A;  4P7I A;  2G35 A;  3U8Z A;  1RRP B;  5LON B;  1IRS A;  2MFQ A;  3ODX A;  3AU5 A;  3O96 A;  2COF A;  4HB2 B;  2XQN M;  5C5B A;  1DYN A;  2D2Q A;  5D3X A;  1ZM0 A;  3ODO A;  4F7U P;  1I2H A;  1MAI A;  1LB1 A;  2X18 A;  1WJ1 A;  1OQN A;  3D8F A;  1MK9 B;  1LW3 A;  5J3Y A;  2CY4 A;  4MT7 A;  2UZR A;  2YS3 A;  2N23 A;  2E2X A;  1QC6 A;  1XKE A;  1PFJ A;  1UNP A;  2P0H A;  2HE7 A;  2BCJ A;  1X86 A;  3TO1 A;  2COD A;  3KY9 A;  1MK7 B;  3VOQ A;  4DXA B;  1PMS A;  3LJU X;  1UNQ A;  5DHA B;  2COA A;  4TYZ A;  4L6E A;  5JP4 A;  3PSC A;  1NTY A;  3DXD A;  1ZC3 B;  2P0D A;  2RNR B;  3SYX A;  5HE3 A;  3BJI A;  4WSF A;  3TVV A;  2VSZ A;  4HAW B;  2RSG A;  1XD4 A;  2DHI A;  2D11 A;  4WVF B;  2KUP A;  1J0W A;  3X23 A;  2EMT A;  1ZSQ A;  3FM8 C;  2W2W A;  1GC7 A;  1QQG A;  1E5W A;  1X05 A;  2UVM A;  4K2O A;  1U5D A;  4NY0 A;  3GYP A;  3D8D A;  1BTN A;  1U29 A;  4A6F B;  3RCP A;  3OAN A;  1XR0 B;  1TJ6 A;  2DYN A;  1FHW A;  4K2P A;  1PLS A;  4HB0 B;  2YF0 A;  2LYD A;  2D4Q A;  2FJL A;  3M1I B;  4GPT B;  1NU2 A;  1TXD A;  2J0J A;  4GN1 A; 
#chains in the Genus database with same CATH topology
 3PEG A;  3QBV B;  2HTH B;  2ELB A;  1UEF A;  1AWE A;  2W2X C;  2RGN B;  3TFM A;  1BAK A;  1SGH A;  2LG1 A;  4CYE A;  1Y5O A;  2YRY A;  3NWD A;  2Z13 A;  4OSN A;  5JHG A;  2YT0 A;  4A5K A;  1V5U A;  3DXC A;  2ROZ B;  1BTK A;  3CXB B;  3KRW A;  3SNH A;  4GMX B;  3U7D A;  2KIE A;  4CHJ A;  1MPH A;  1V89 A;  2DX1 A;  2DKQ A;  4GMV A;  5HE0 A;  3G9W A;  1V5M A;  4KAX B;  5D27 A;  5J3T A;  3KSY A;  1MKE A;  1DDW A;  5D3V A;  1J19 A;  2YT1 A;  1M7E A;  4HAX B;  3P7Z A;  1UPQ A;  5CLQ B;  1FOE A;  5JLJ B;  3FVC A;  2L1C A;  2IFS A;  2Q13 A;  2NZ8 B;  1V61 A;  3SV1 A;  4F7H A;  2KGX B;  3A8P A;  3V5W A;  2DHK A;  2V76 A;  2Z0P A;  2K2J A;  2OQB A;  4HAY B;  1Q67 A;  2ROV A;  2H7D A;  2Z14 A;  5J3Q A;  4HDQ A;  4HB3 B;  5KCV A;  3ODW A;  4IFS A;  3B77 A;  3HQC A;  5DHF B;  4A6K A;  4ZRK A;  2D9Z A;  1ZVR A;  4KHO A;  4D0N B;  1U5E A;  1EGX A;  4TKN A;  3AJ4 A;  2DYQ A;  2I5F A;  4PQ0 A;  1EF1 A;  1P3R A;  3FEH A;  2QKM A;  1DRO A;  4D6W A;  2VKI A;  1U27 A;  1WJM A;  1I7A A;  2QKL A;  2DTC A;  4DX8 A;  5D3Y A;  3ULC A;  3KRX A;  2LUL A;  4QJ5 B;  1V5P A;  1AQC A;  1NI2 A;  3SUZ A;  4ZRJ A;  3TW1 A;  4C0A A;  3AU4 A;  1WI1 A;  5C6R A;  2GS0 A;  4IOY X;  1DDM A;  5LG4 B;  3PP2 A;  2KIG A;  2P0F A;  1KZG A;  2DFK A;  2AL6 A;  1P6S A;  4GZU A;  4HAU B;  2YS5 A;  3PVL A;  1Z87 A;  1XOD A;  4GNK B;  2J0M A;  2OTX A;  1U5G A;  1GC6 A;  4KVG B;  4H8S A;  2KR0 A;  4CHM A;  5L81 A;  3HSA A;  1X11 A;  3QIJ A;  3WA0 A;  1WGQ A;  2ZKM X;  3D8E A;  4ZRI A;  4HDO A;  4NSW A;  2D10 A;  1EVH A;  5I2M A;  1X1G A;  3N7C A;  2H7E A;  3KZ1 A;  5IRS A;  2DA0 A;  5GOW B;  4B6H A;  1KI1 B;  1U2B A;  2LKO A;  4XWX A;  5KQ1 A;  1H4R A;  1FAO A;  3ZVR A;  4GXB A;  4DBB A;  2RVB B;  2KUQ A;  1T77 A;  2M38 A;  3CIK A;  2EJ8 A;  2I5C A;  4EMO A;  1FHX A;  2DLW A;  4HAT B;  3TCA A;  3F0W A;  2COC A;  4HSI A;  2K2U A;  3QWM A;  2MDX A;  3ULB A;  1BWN A;  1MI1 A;  2ZPY A;  4KHB A;  3MPX A;  2ELA A;  4DIX A;  3SO6 A;  3MDB C;  4YL8 A;  2YS1 A;  5D3W A;  4HB4 B;  3P6A A;  2CAY A;  1DBH A;  5C79 A;  2Z0O A;  2K49 A;  3UZT A;  5EFX A;  1V88 A;  4L1R A;  4A6H A;  1XCG A;  1K5G B;  2ADZ A;  4Z2N A;  2Y8F A;  2Z0Q A;  1RJ2 A;  2M14 A;  3NSU A;  2I1J A;  1H10 A;  4BBK A;  1DDV A;  3F5R A;  1FHO A;  5DIF B;  5FI1 A;  3GYO A;  4HAZ B;  2D9Y A;  2FJU B;  4IAP A;  3PVU A;  3T06 A;  4PNK A;  3PZD A;  2D9W A;  4Y94 A;  1K5D B;  5C5B B;  1MIX A;  2I1K A;  2DHJ A;  1WG7 A;  2GCL A;  2R0D A;  5DI9 B;  2CRF A;  1TQZ A;  1SHC A;  2R2Y A;  5DH9 B;  2DX5 A;  4WJ7 A;  4GOU A;  1UNR A;  4EKU A;  3FSS A;  2LOZ A;  1N3H A;  4K17 A;  2R09 A;  3A8Q A;  5JHH A;  1EAZ A;  1M7R A;  1ISN A;  2N0Y A;  3NW8 A;  3BIN A;  5M4Y B;  3VIA A;  3NWA A;  5HE2 A;  4Z2M B;  1W1H A;  1ZC4 B;  1W1D A;  2VRW B;  2YVC A;  1P5T A;  1XX0 A;  1FB8 A;  2K8E A;  2AEH A;  2J0K A;  2MWN B;  3ZDT A;  5C16 A;  3ML4 A;  4KHA A;  4DX9 0;  2YSZ A;  5HE1 A;  2MKR A;  1FGY A;  4HHV A;  2JP2 A;  2K00 A;  3PG7 A;  4KHB B;  1Y19 B;  1OY2 A;  2DKP A;  2L2I A;  1ZYI A;  2Y7B A;  2KCJ A;  2NMB A;  2PZ1 A;  4F7G A;  2CY5 A;  3A98 B;  1NTV A;  2RLO A;  2LOX A;  1U5F A;  2D9X A;  4HAV B;  4GN1 A;  3DXE A;  2IYB A;  1W1G A;  4MY6 A;  2D9V A;  4QJ4 B;  2GJY A;  1MIZ B;  5LOP B;  1X1F A;  4QXA B;  5KQ4 A;  2DN6 A;  2Y8G A;  5CLL B;  4EJN A;  3PVW A;  2W2X D;  4K81 A;  2UZS A;  1OMW A;  2J59 M;  5FI0 A;  4YON A;  1WVH A;  2P8V A;  2GUM A;  1FGZ A;  3HIE A;  3HW2 B;  1KZ7 A;  2EMS A;  1UPR A;  3IVF A;  2GCJ A;  4MK0 A;  3WYF B;  3HK0 A;  1GG3 A;  4A6F A;  1B55 A;  2EC1 A;  2RUK B;  1WGU A;  4P7I A;  2G35 A;  3U8Z A;  1RRP B;  5LON B;  1IRS A;  2MFQ A;  3ODX A;  3AU5 A;  3O96 A;  2RRF A;  2COF A;  4HB2 B;  4CSQ A;  2XQN M;  5C5B A;  3OHM B;  1DYN A;  2D2Q A;  5D3X A;  1ZM0 A;  3ODO A;  4F7U P;  1I2H A;  1MAI A;  1LB1 A;  2X18 A;  1WJ1 A;  3NWF A;  1OQN A;  3D8F A;  1MK9 B;  1LW3 A;  2NBV A;  5J3Y A;  5I2S A;  2CY4 A;  4MT7 A;  2UZR A;  2YS3 A;  2N23 A;  2E2X A;  1QC6 A;  1XKE A;  1PFJ A;  1UNP A;  2P0H A;  2HE7 A;  2BCJ A;  1X86 A;  3TO1 A;  2COD A;  3KY9 A;  1MK7 B;  3VOQ A;  4DXA B;  1PMS A;  3LJU X;  1UNQ A;  5DHA B;  2COA A;  4TYZ A;  4L6E A;  5JP4 A;  3PSC A;  2Z59 A;  1NTY A;  3DXD A;  1ZC3 B;  2P0D A;  2RNR B;  3SYX A;  5HE3 A;  3BJI A;  4WSF A;  3TVV A;  2VSZ A;  4HAW B;  2YT2 A;  2RSG A;  1XD4 A;  2DHI A;  2D11 A;  4QJ3 B;  4WVF B;  2KUP A;  1J0W A;  3X23 A;  2EMT A;  3FM8 C;  2W2W A;  1GC7 A;  1QQG A;  1E5W A;  3DCX A;  2Z4D A;  1X05 A;  2UVM A;  4K2O A;  3A58 A;  1U5D A;  4NY0 A;  3GYP A;  3D8D A;  1BTN A;  1U29 A;  4A6F B;  3RCP A;  3OAN A;  1XR0 B;  1TJ6 A;  2DYN A;  1FHW A;  4K2P A;  1PLS A;  4HB0 B;  4OT1 A;  2YF0 A;  2LYD A;  2D4Q A;  2FJL A;  3M1I B;  4GPT B;  1NU2 A;  1TXD A;  2J0J A;  3U12 A;  1ZSQ A; 
#chains in the Genus database with same CATH homology
 3PEG A;  3QBV B;  2HTH B;  2ELB A;  1UEF A;  1AWE A;  2W2X C;  2RGN B;  3TFM A;  1BAK A;  1SGH A;  2LG1 A;  4CYE A;  1Y5O A;  2YRY A;  5JHG A;  2YT0 A;  4A5K A;  1V5U A;  3DXC A;  2ROZ B;  1BTK A;  3CXB B;  3KRW A;  3SNH A;  4GMX B;  3U7D A;  4CHJ A;  1MPH A;  1V89 A;  2DX1 A;  2DKQ A;  4GMV A;  5HE0 A;  3G9W A;  1V5M A;  4KAX B;  5D27 A;  5J3T A;  3KSY A;  1MKE A;  1DDW A;  5D3V A;  1J19 A;  2YT1 A;  1M7E A;  4HAX B;  3P7Z A;  1UPQ A;  5CLQ B;  1FOE A;  5JLJ B;  2L1C A;  2IFS A;  2Q13 A;  2NZ8 B;  1V61 A;  3SV1 A;  4F7H A;  2KGX B;  3A8P A;  3V5W A;  2DHK A;  2V76 A;  2Z0P A;  2K2J A;  2OQB A;  4HAY B;  1Q67 A;  2ROV A;  2H7D A;  5J3Q A;  4HDQ A;  4HB3 B;  5KCV A;  3ODW A;  4IFS A;  3HQC A;  5DHF B;  4A6K A;  4ZRK A;  2D9Z A;  1ZVR A;  4KHO A;  4D0N B;  1U5E A;  1EGX A;  4TKN A;  3AJ4 A;  2DYQ A;  2I5F A;  4PQ0 A;  1EF1 A;  1P3R A;  3FEH A;  2QKM A;  1DRO A;  2VKI A;  1U27 A;  1WJM A;  1I7A A;  2QKL A;  2DTC A;  4DX8 A;  5D3Y A;  3ULC A;  3KRX A;  2LUL A;  1V5P A;  1AQC A;  1NI2 A;  3SUZ A;  4ZRJ A;  3TW1 A;  4C0A A;  3AU4 A;  1WI1 A;  5C6R A;  2GS0 A;  4IOY X;  1DDM A;  3PP2 A;  2P0F A;  1KZG A;  2DFK A;  2AL6 A;  1P6S A;  4GZU A;  4HAU B;  2YS5 A;  3PVL A;  1Z87 A;  1XOD A;  2J0M A;  2OTX A;  1U5G A;  1GC6 A;  4KVG B;  4H8S A;  4CHM A;  5L81 A;  1X11 A;  3QIJ A;  3WA0 A;  1WGQ A;  3D8E A;  4ZRI A;  4HDO A;  4NSW A;  2D10 A;  1EVH A;  1X1G A;  3N7C A;  2H7E A;  3KZ1 A;  2DA0 A;  5GOW B;  4B6H A;  1KI1 B;  1U2B A;  2LKO A;  4XWX A;  5KQ1 A;  1H4R A;  1FAO A;  3ZVR A;  4GXB A;  4DBB A;  2RVB B;  3CIK A;  2M38 A;  2EJ8 A;  2I5C A;  4EMO A;  1FHX A;  2DLW A;  4HAT B;  3TCA A;  3F0W A;  2COC A;  2K2U A;  3QWM A;  2MDX A;  3ULB A;  1BWN A;  2ZPY A;  3MPX A;  2ELA A;  3SO6 A;  3MDB C;  4YL8 A;  2YS1 A;  5D3W A;  4HB4 B;  3P6A A;  2CAY A;  1DBH A;  5C79 A;  2Z0O A;  3UZT A;  5EFX A;  1V88 A;  4A6H A;  1XCG A;  1K5G B;  2ADZ A;  4Z2N A;  2Y8F A;  2Z0Q A;  1RJ2 A;  2M14 A;  3NSU A;  2I1J A;  1H10 A;  4BBK A;  1DDV A;  3F5R A;  1FHO A;  5DIF B;  5FI1 A;  3GYO A;  4HAZ B;  2D9Y A;  4IAP A;  3PVU A;  3T06 A;  4PNK A;  3PZD A;  2D9W A;  4Y94 A;  1K5D B;  5C5B B;  1MIX A;  2I1K A;  2DHJ A;  1WG7 A;  2GCL A;  2R0D A;  5DI9 B;  2CRF A;  1TQZ A;  1SHC A;  5DH9 B;  2DX5 A;  4WJ7 A;  1UNR A;  4EKU A;  3FSS A;  2LOZ A;  1N3H A;  4K17 A;  2R09 A;  3A8Q A;  5JHH A;  1EAZ A;  1M7R A;  1ISN A;  2N0Y A;  3BIN A;  3VIA A;  5HE2 A;  4Z2M B;  1W1H A;  1ZC4 B;  1W1D A;  2VRW B;  2YVC A;  1P5T A;  1XX0 A;  1FB8 A;  2AEH A;  2J0K A;  2MWN B;  3ZDT A;  5C16 A;  3ML4 A;  4KHA A;  4DX9 0;  2YSZ A;  5HE1 A;  2MKR A;  1FGY A;  4HHV A;  2JP2 A;  2K00 A;  3PG7 A;  4KHB B;  1Y19 B;  1OY2 A;  2DKP A;  2L2I A;  2Y7B A;  2KCJ A;  2NMB A;  2PZ1 A;  4F7G A;  2CY5 A;  3A98 B;  1NTV A;  2RLO A;  2LOX A;  1U5F A;  2D9X A;  4HAV B;  3DXE A;  2IYB A;  1W1G A;  4MY6 A;  2D9V A;  2GJY A;  1MIZ B;  5LOP B;  1X1F A;  5KQ4 A;  2DN6 A;  2Y8G A;  5CLL B;  4EJN A;  3PVW A;  2W2X D;  4K81 A;  2UZS A;  1OMW A;  2J59 M;  5FI0 A;  4YON A;  1WVH A;  2P8V A;  1FGZ A;  3HW2 B;  1KZ7 A;  2EMS A;  1UPR A;  3IVF A;  2GCJ A;  4MK0 A;  3WYF B;  3HK0 A;  1GG3 A;  4A6F A;  1B55 A;  2EC1 A;  2RUK B;  1WGU A;  4P7I A;  2G35 A;  3U8Z A;  1RRP B;  5LON B;  1IRS A;  2MFQ A;  3ODX A;  3AU5 A;  3O96 A;  2COF A;  4HB2 B;  2XQN M;  5C5B A;  1DYN A;  2D2Q A;  5D3X A;  1ZM0 A;  3ODO A;  4F7U P;  1I2H A;  1MAI A;  1LB1 A;  2X18 A;  1WJ1 A;  1OQN A;  3D8F A;  1MK9 B;  1LW3 A;  5J3Y A;  2CY4 A;  4MT7 A;  2UZR A;  2YS3 A;  2N23 A;  2E2X A;  1QC6 A;  1XKE A;  1PFJ A;  1UNP A;  2P0H A;  2HE7 A;  2BCJ A;  1X86 A;  3TO1 A;  2COD A;  3KY9 A;  1MK7 B;  3VOQ A;  4DXA B;  1PMS A;  3LJU X;  1UNQ A;  5DHA B;  2COA A;  4TYZ A;  4L6E A;  5JP4 A;  3PSC A;  1NTY A;  3DXD A;  1ZC3 B;  2P0D A;  2RNR B;  3SYX A;  5HE3 A;  3BJI A;  4WSF A;  3TVV A;  2VSZ A;  4HAW B;  2RSG A;  1XD4 A;  2DHI A;  2D11 A;  4WVF B;  2KUP A;  1J0W A;  3X23 A;  2EMT A;  1ZSQ A;  3FM8 C;  2W2W A;  1GC7 A;  1QQG A;  1E5W A;  1X05 A;  2UVM A;  4K2O A;  1U5D A;  4NY0 A;  3GYP A;  3D8D A;  1BTN A;  1U29 A;  4A6F B;  3RCP A;  3OAN A;  1XR0 B;  1TJ6 A;  2DYN A;  1FHW A;  4K2P A;  1PLS A;  4HB0 B;  2YF0 A;  2LYD A;  2D4Q A;  2FJL A;  3M1I B;  4GPT B;  1NU2 A;  1TXD A;  2J0J A;  4GN1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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