1QQGA

Crystal structure of the ph-ptb targeting region of irs-1
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
251
structure length
207
Chain Sequence
DVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAPKRSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHAFKEVWQVILKPKGLGQTKNLIGIYRLCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQVDDSVVAQNMHETILEAMRAMSD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the pleckstrin homology-phosphotyrosine binding (PH-PTB) targeting region of insulin receptor substrate 1.
pubmed doi rcsb
molecule keywords INSULIN RECEPTOR SUBSTRATE 1
molecule tags Signal transduction
source organism Homo sapiens
total genus 51
structure length 207
sequence length 251
chains with identical sequence B
ec nomenclature
pdb deposition date 1999-06-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00169 PH PH domain
A PF02174 IRS PTB domain (IRS-1 type)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 1qqgA02
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 1qqgA01
4KHOA 4MK0A 4A6FB 4D0NB 1TXDA 1ISNA 2KCJA 1AWEA 1QC6A 3AJ4A 3SNHA 3T06A 5D3XA 2D9ZA 5HE2A 4DX90 3WYFB 2D4QA 1V61A 1DBHA 1LB1A 2Y8GA 2CY4A 4HAZB 1AQCA 3PP2A 1H10A 2VRWB 3M1IB 4A5KA 2HE7A 5JHGA 1X86A 2J0KA 3AU5A 3F0WA 1WJMA 5DI9B 4GPTB 3U8ZA 2OQBA 1UPRA 3BJIA 4C0AA 1M7EA 1K5GB 2L1CA 1Y5OA 1WG7A 5EFXA 1TJ6A 4HAUB 5D3YA 1X11A 2Z0OA 4B6HA 1ZC3B 1MK9B 1U5GA 3PEGA 4CHJA 2M14A 1K5DB 3LJUX 1NTYA 1TQZA 4A6FA 2EC1A 2MWNB 2I1JA 4P7IA 2DN6A 2I5CA 4XWXA 2MDXA 1J19A 4NY0A 4IOYX 1BTNA 1OQNA 5J3QA 2EMTA 4HB2B 1XKEA 4KHBB 1W1DA 1MAIA 3AU4A 1MPHA 5D3WA 4CHMA 4DX8A 4BBKA 3SV1A 4HAWB 3A98B 2YSZA 5CLLB 3A8PA 3KRXA 1EF1A 2YF0A 3DXDA 2YS1A 2AL6A 1DYNA 1FGYA 5LOPB 4WJ7A 2DYQA 2Y7BA 3PZDA 1U27A 3IVFA 3ODXA 2X18A 1KZ7A 4HHVA 1FOEA 1UEFA 5JHHA 2D9VA 4PQ0A 2COAA 2D9WA 2D2QA 3P7ZA 2RNRB 2VKIA 2H7DA 1ZVRA 3OANA 1XR0B 2D10A 4K81A 1FHOA 1DDVA 2DFKA 4IAPA 2I1KA 2ZPYA 1WVHA 4HB0B 2GCJA 2D11A 3D8EA 1GC7A 3ZVRA 5C6RA 2LULA 2J0MA 2D9XA 4K17A 4EMOA 5D27A 1X05A 5C79A 2R0DA 1UNQA 3RCPA 1WGUA 2G35A 5HE1A 3UZTA 3ODOA 1XCGA 2YVCA 1DDWA 5JP4A 2ADZA 1MK7B 2W2WA 3N7CA 1BAKA 3KSYA 3ODWA 3ZDTA 3CXBB 3ULCA 5FI1A 1X1FA 2IYBA 4HATB 2DYNA 4Z2MB 2JP2A 2GJYA 2COCA 2P0DA 1SHCA 1LW3A 1FAOA 4TYZA 2EJ8A 3PG7A 2RVBB 1WI1A 3SYXA 1P5TA 2BCJA 2I5FA 5C16A 4HB3B 1UNRA 3NSUA 2YT1A 1XD4A 4GMVA 1MKEA 2R09A 4A6KA 1FGZA 1V5UA 2PZ1A 1XX0A 4ZRKA 1GC6A 3SUZA 2ROVA 4NSWA 5HE0A 2DHIA 1H4RA 1FHWA 3X23A 4DBBA 5DIFB 1EGXA 4DXAB 2QKMA 2VSZA 3A8QA 1PLSA 4CYEA 2LYDA 2P0FA 2UZSA 2W2XC 2CRFA 1N3HA 3V5WA 3TVVA 3WA0A 3F5RA 5C5BB 4HAVB 3PSCA 1X1GA 1MIXA 1Q67A 5KQ1A 4PNKA 3DXEA 2N0YA 3HQCA 3BINA 2Q13A 3QIJA 3KY9A 3QWMA 1W1HA 2N23A 2ELAA 2IFSA 4KAXB 2YRYA 3PVLA 4HB4B 1DDMA 1J0WA 1ZC4B 2DKQA 2MKRA 2UZRA 3U7DA 4TKNA 5LONB 2AEHA 2DX5A 3CIKA 4WVFB 1M7RA 2K2JA 3GYOA 3DXCA 1KZGA 1V89A 5J3TA 2KUPA 1PFJA 2RLOA 2YT0A 2YS3A 1I2HA 1BWNA 4KHAA 3TCAA 2H7EA 3MDBC 2Y8FA 1KI1B 5C5BA 1OMWA 1E5WA 3TO1A 4YONA 3QBVB 1ZM0A 5CLQB 5J3YA 2RSGA 4A6HA 1V88A 2ELBA 2LOZA 3VIAA 2E2XA 4YL8A 5FI0A 2DTCA 3HK0A 4L6EA 1B55A 2UVMA 4F7HA 1NU2A 4Y94A 3FEHA 3ULBA 1V5PA 5D3VA 2Z0QA 2QKLA 1U2BA 2P0HA 1U5DA 2FJLA 3G9WA 2CY5A 4GN1A 4EKUA 2CODA 2J59M 1QQGA 3D8DA 1Y19B 1RRPB 3P6AA 2NZ8B 1NTVA 1FB8A 2DX1A 3VOQA 3PVUA 2DKPA 2CAYA 1ZSQA 2DLWA 3MPXA 5L81A 2GCLA 3GYPA 1EVHA 5DHFB 1MIZB 1SGHA 1RJ2A 4F7GA 3KZ1A 4EJNA 1BTKA 5JLJB 3PVWA 2RGNB 1WGQA 1UNPA 4IFSA 2D9YA 1XODA 2XQNM 5DH9B 2M38A 2DA0A 2YS5A 1P6SA 4F7UP 1I7AA 4MY6A 5KQ4A 5HE3A 2L2IA 4MT7A 2EMSA 1EAZA 3HW2B 1PMSA 4Z2NA 2P8VA 3FM8C 1U5EA 1OY2A 1P3RA 4GZUA 5GOWB 2J0JA 2LKOA 4K2OA 4HAXB 2GS0A 2DHKA 4HDOA 2K00A 4K2PA 1IRSA 2V76A 1WJ1A 3O96A 4KVGB 1U29A 1DROA 4H8SA 1U5FA 3KRWA 2DHJA 1GG3A 4HDQA 1NI2A 2OTXA 3TFMA 5DHAB 2RUKB 2COFA 2W2XD 5KCVA 2MFQA 2KGXB 4ZRIA 3TW1A 2K2UA 4GXBA 3ML4A 2HTHB 3SO6A 1UPQA 4HAYB 2LOXA 1V5MA 2Z0PA 4ZRJA 1Z87A 1W1GA 2ROZB 3D8FA 4WSFA 1FHXA 2LG1A 2NMBA 4GMXB 3FSSA
chains in the Genus database with same CATH superfamily
2KIGA 4KHOA 4MK0A 4OT1A 4A6FB 4D0NB 1TXDA 1ISNA 3OHMB 2KCJA 1AWEA 1QC6A 3AJ4A 3SNHA 3T06A 5D3XA 2D9ZA 5HE2A 4DX90 3WYFB 2D4QA 1V61A 1DBHA 1LB1A 2Y8GA 2CY4A 4HAZB 1AQCA 3PP2A 1H10A 2VRWB 3M1IB 4A5KA 2HE7A 5JHGA 5I2SA 1X86A 2J0KA 3AU5A 2RRFA 4CSQA 3F0WA 1WJMA 5DI9B 4GPTB 3U8ZA 2OQBA 1UPRA 3BJIA 4C0AA 1M7EA 1K5GB 2L1CA 1Y5OA 1WG7A 5EFXA 1TJ6A 3A58A 4HAUB 5D3YA 1X11A 2Z0OA 4B6HA 1ZC3B 1MK9B 1U5GA 3PEGA 4CHJA 2M14A 1K5DB 3LJUX 1NTYA 1TQZA 4A6FA 2EC1A 2MWNB 2I1JA 4QJ4B 4P7IA 2DN6A 2I5CA 4XWXA 1ZYIA 2MDXA 1J19A 4NY0A 4IOYX 1BTNA 4D6WA 1OQNA 5J3QA 2EMTA 4HB2B 1XKEA 4KHBB 1W1DA 1MAIA 3AU4A 1MPHA 5D3WA 4CHMA 4DX8A 4BBKA 2R2YA 3SV1A 3B77A 4HAWB 3A98B 2YSZA 5CLLB 3A8PA 3KRXA 1EF1A 5IRSA 2YF0A 3DXDA 3NW8A 2YS1A 2AL6A 1DYNA 1FGYA 5LOPB 4WJ7A 2DYQA 2Y7BA 3PZDA 1U27A 3IVFA 3ODXA 2X18A 1KZ7A 4HHVA 1FOEA 1UEFA 5JHHA 2D9VA 4PQ0A 2COAA 2D9WA 2D2QA 3P7ZA 2RNRB 2VKIA 2H7DA 1ZVRA 3OANA 1XR0B 2D10A 4K81A 1FHOA 1DDVA 2KIEA 2DFKA 4IAPA 2I1KA 2ZPYA 1WVHA 4HB0B 2GCJA 2D11A 3D8EA 1GC7A 3ZVRA 5C6RA 4QJ3B 4KHBA 2LULA 2J0MA 2D9XA 3HIEA 4K17A 4EMOA 5D27A 1X05A 5C79A 2R0DA 1UNQA 3RCPA 1WGUA 2G35A 5HE1A 3UZTA 3ODOA 1XCGA 2YVCA 1DDWA 5JP4A 2ADZA 1MK7B 2W2WA 3N7CA 1BAKA 3KSYA 3ODWA 3ZDTA 3CXBB 3ULCA 5FI1A 1X1FA 2IYBA 3U12A 2GUMA 4HATB 2FJUB 2DYNA 4Z2MB 2JP2A 5M4YB 2Z59A 2GJYA 2COCA 2P0DA 1SHCA 1LW3A 1FAOA 4TYZA 2EJ8A 3PG7A 2RVBB 1T77A 1WI1A 3SYXA 1P5TA 2Z13A 2BCJA 2I5FA 5C16A 4HB3B 1UNRA 3NSUA 3HSAA 2YT1A 1XD4A 4GMVA 1MKEA 2R09A 4A6KA 1FGZA 1V5UA 2PZ1A 1XX0A 4ZRKA 1GC6A 3SUZA 2ROVA 4NSWA 5HE0A 2DHIA 1H4RA 1FHWA 4L1RA 2ZKMX 3X23A 4DBBA 5DIFB 1EGXA 4DXAB 2QKMA 2VSZA 3A8QA 1PLSA 2K8EA 4CYEA 2LYDA 2P0FA 2UZSA 2W2XC 2CRFA 1N3HA 3V5WA 3TVVA 3WA0A 3F5RA 5C5BB 4HAVB 3PSCA 1X1GA 1MIXA 1Q67A 5KQ1A 4PNKA 3DXEA 2N0YA 3HQCA 3BINA 2Q13A 3QIJA 4GNKB 3KY9A 3QWMA 1W1HA 2N23A 2ELAA 2IFSA 4KAXB 2YRYA 3PVLA 4HB4B 1DDMA 1J0WA 1ZC4B 2DKQA 2MKRA 2UZRA 3U7DA 4TKNA 4HSIA 5LONB 2AEHA 2DX5A 3CIKA 4WVFB 1M7RA 2K2JA 3GYOA 1MI1A 3DXCA 1KZGA 1V89A 5J3TA 4DIXA 2KUPA 1PFJA 2RLOA 2YT0A 2YS3A 1I2HA 1BWNA 4KHAA 3TCAA 2H7EA 3DCXA 3MDBC 2Y8FA 1KI1B 5C5BA 1OMWA 1E5WA 3TO1A 4YONA 3QBVB 1ZM0A 5CLQB 5J3YA 2RSGA 4A6HA 1V88A 2ELBA 2LOZA 3FVCA 3VIAA 2E2XA 4YL8A 5FI0A 2DTCA 4OSNA 3HK0A 3NWAA 1B55A 2UVMA 4L6EA 4F7HA 1NU2A 4Y94A 3FEHA 3ULBA 1V5PA 5D3VA 2Z0QA 2QKLA 1U2BA 2P0HA 1U5DA 2Z14A 2FJLA 3G9WA 2CY5A 4GN1A 4EKUA 2CODA 2J59M 1QQGA 3D8DA 1Y19B 1RRPB 2K49A 3P6AA 2NZ8B 1NTVA 5I2MA 1FB8A 2DX1A 3VOQA 3PVUA 2DKPA 2CAYA 1ZSQA 2DLWA 3MPXA 5L81A 2GCLA 3GYPA 1EVHA 3NWFA 5DHFB 1MIZB 1SGHA 1RJ2A 4F7GA 3KZ1A 4EJNA 1BTKA 5JLJB 3PVWA 2RGNB 1WGQA 1UNPA 4IFSA 2D9YA 1XODA 2XQNM 5DH9B 2M38A 2DA0A 2YS5A 1P6SA 3NWDA 4F7UP 1I7AA 4MY6A 5KQ4A 5HE3A 2L2IA 4MT7A 2EMSA 1EAZA 3HW2B 1PMSA 2YT2A 4Z2NA 2P8VA 3FM8C 1U5EA 1OY2A 4QJ5B 1P3RA 4GZUA 5GOWB 2J0JA 2LKOA 4K2OA 2Z4DA 4HAXB 2GS0A 2DHKA 4HDOA 2K00A 4QXAB 4K2PA 1IRSA 2V76A 1WJ1A 3O96A 4KVGB 1U29A 1DROA 2KUQA 4H8SA 1U5FA 3KRWA 2DHJA 1GG3A 4HDQA 1NI2A 2OTXA 3TFMA 5DHAB 2RUKB 2COFA 2W2XD 5KCVA 2MFQA 2KGXB 4ZRIA 4GOUA 3TW1A 2K2UA 4GXBA 3ML4A 2HTHB 2KR0A 3SO6A 1UPQA 4HAYB 2LOXA 1V5MA 2Z0PA 4ZRJA 1Z87A 5LG4B 1W1GA 2ROZB 3D8FA 4WSFA 2NBVA 1FHXA 2LG1A 2NMBA 4GMXB 3FSSA
chains in the Genus database with same CATH topology
4KHOA 4MK0A 4A6FB 4D0NB 1TXDA 1ISNA 2KCJA 1AWEA 1QC6A 3AJ4A 3SNHA 3T06A 5D3XA 2D9ZA 5HE2A 4DX90 3WYFB 2D4QA 1V61A 1DBHA 1LB1A 2Y8GA 2CY4A 4HAZB 1AQCA 3PP2A 1H10A 2VRWB 3M1IB 4A5KA 2HE7A 5JHGA 1X86A 2J0KA 3AU5A 3F0WA 1WJMA 5DI9B 4GPTB 3U8ZA 2OQBA 1UPRA 3BJIA 4C0AA 1M7EA 1K5GB 2L1CA 1Y5OA 1WG7A 5EFXA 1TJ6A 4HAUB 5D3YA 1X11A 2Z0OA 4B6HA 1ZC3B 1MK9B 1U5GA 3PEGA 4CHJA 2M14A 1K5DB 3LJUX 1NTYA 1TQZA 4A6FA 2EC1A 2MWNB 2I1JA 4P7IA 2DN6A 2I5CA 4XWXA 2MDXA 1J19A 4NY0A 4IOYX 1BTNA 1OQNA 5J3QA 2EMTA 4HB2B 1XKEA 4KHBB 1W1DA 1MAIA 3AU4A 1MPHA 5D3WA 4CHMA 4DX8A 4BBKA 3SV1A 4HAWB 3A98B 2YSZA 5CLLB 3A8PA 3KRXA 1EF1A 2YF0A 3DXDA 2YS1A 2AL6A 1DYNA 1FGYA 5LOPB 4WJ7A 2DYQA 2Y7BA 3PZDA 1U27A 3IVFA 3ODXA 2X18A 1KZ7A 4HHVA 1FOEA 1UEFA 5JHHA 2D9VA 4PQ0A 2COAA 2D9WA 2D2QA 3P7ZA 2RNRB 2VKIA 2H7DA 1ZVRA 3OANA 1XR0B 2D10A 4K81A 1FHOA 1DDVA 2DFKA 4IAPA 2I1KA 2ZPYA 1WVHA 4HB0B 2GCJA 2D11A 3D8EA 1GC7A 3ZVRA 5C6RA 2LULA 2J0MA 2D9XA 4K17A 4EMOA 5D27A 1X05A 5C79A 2R0DA 1UNQA 3RCPA 1WGUA 2G35A 5HE1A 3UZTA 3ODOA 1XCGA 2YVCA 1DDWA 5JP4A 2ADZA 1MK7B 2W2WA 3N7CA 1BAKA 3KSYA 3ODWA 3ZDTA 3CXBB 3ULCA 5FI1A 1X1FA 2IYBA 4HATB 2DYNA 4Z2MB 2JP2A 2GJYA 2COCA 2P0DA 1SHCA 1LW3A 1FAOA 4TYZA 2EJ8A 3PG7A 2RVBB 1WI1A 3SYXA 1P5TA 2BCJA 2I5FA 5C16A 4HB3B 1UNRA 3NSUA 2YT1A 1XD4A 4GMVA 1MKEA 2R09A 4A6KA 1FGZA 1V5UA 2PZ1A 1XX0A 4ZRKA 1GC6A 3SUZA 2ROVA 4NSWA 5HE0A 2DHIA 1H4RA 1FHWA 3X23A 4DBBA 5DIFB 1EGXA 4DXAB 2QKMA 2VSZA 3A8QA 1PLSA 4CYEA 2LYDA 2P0FA 2UZSA 2W2XC 2CRFA 1N3HA 3V5WA 3TVVA 3WA0A 3F5RA 5C5BB 4HAVB 3PSCA 1X1GA 1MIXA 1Q67A 5KQ1A 4PNKA 3DXEA 2N0YA 3HQCA 3BINA 2Q13A 3QIJA 3KY9A 3QWMA 1W1HA 2N23A 2ELAA 2IFSA 4KAXB 2YRYA 3PVLA 4HB4B 1DDMA 1J0WA 1ZC4B 2DKQA 2MKRA 2UZRA 3U7DA 4TKNA 5LONB 2AEHA 2DX5A 3CIKA 4WVFB 1M7RA 2K2JA 3GYOA 3DXCA 1KZGA 1V89A 5J3TA 2KUPA 1PFJA 2RLOA 2YT0A 2YS3A 1I2HA 1BWNA 4KHAA 3TCAA 2H7EA 3MDBC 2Y8FA 1KI1B 5C5BA 1OMWA 1E5WA 3TO1A 4YONA 3QBVB 1ZM0A 5CLQB 5J3YA 2RSGA 4A6HA 1V88A 2ELBA 2LOZA 3VIAA 2E2XA 4YL8A 5FI0A 2DTCA 3HK0A 4L6EA 1B55A 2UVMA 4F7HA 1NU2A 4Y94A 3FEHA 3ULBA 1V5PA 5D3VA 2Z0QA 2QKLA 1U2BA 2P0HA 1U5DA 2FJLA 3G9WA 2CY5A 4GN1A 4EKUA 2CODA 2J59M 1QQGA 3D8DA 1Y19B 1RRPB 3P6AA 2NZ8B 1NTVA 1FB8A 2DX1A 3VOQA 3PVUA 2DKPA 2CAYA 1ZSQA 2DLWA 3MPXA 5L81A 2GCLA 3GYPA 1EVHA 5DHFB 1MIZB 1SGHA 1RJ2A 4F7GA 3KZ1A 4EJNA 1BTKA 5JLJB 3PVWA 2RGNB 1WGQA 1UNPA 4IFSA 2D9YA 1XODA 2XQNM 5DH9B 2M38A 2DA0A 2YS5A 1P6SA 4F7UP 1I7AA 4MY6A 5KQ4A 5HE3A 2L2IA 4MT7A 2EMSA 1EAZA 3HW2B 1PMSA 4Z2NA 2P8VA 3FM8C 1U5EA 1OY2A 1P3RA 4GZUA 5GOWB 2J0JA 2LKOA 4K2OA 4HAXB 2GS0A 2DHKA 4HDOA 2K00A 4K2PA 1IRSA 2V76A 1WJ1A 3O96A 4KVGB 1U29A 1DROA 4H8SA 1U5FA 3KRWA 2DHJA 1GG3A 4HDQA 1NI2A 2OTXA 3TFMA 5DHAB 2RUKB 2COFA 2W2XD 5KCVA 2MFQA 2KGXB 4ZRIA 3TW1A 2K2UA 4GXBA 3ML4A 2HTHB 3SO6A 1UPQA 4HAYB 2LOXA 1V5MA 2Z0PA 4ZRJA 1Z87A 1W1GA 2ROZB 3D8FA 4WSFA 1FHXA 2LG1A 2NMBA 4GMXB 3FSSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4KHO A;  4MK0 A;  4A6F B;  4D0N B;  1TXD A;  1ISN A;  2KCJ A;  1AWE A;  1QC6 A;  3AJ4 A;  3SNH A;  3T06 A;  5D3X A;  2D9Z A;  5HE2 A;  4DX9 0;  3WYF B;  2D4Q A;  1V61 A;  1DBH A;  1LB1 A;  2Y8G A;  2CY4 A;  4HAZ B;  1AQC A;  3PP2 A;  1H10 A;  2VRW B;  3M1I B;  4A5K A;  2HE7 A;  5JHG A;  1X86 A;  2J0K A;  3AU5 A;  3F0W A;  1WJM A;  5DI9 B;  4GPT B;  3U8Z A;  2OQB A;  1UPR A;  3BJI A;  4C0A A;  1M7E A;  1K5G B;  2L1C A;  1Y5O A;  1WG7 A;  5EFX A;  1TJ6 A;  4HAU B;  5D3Y A;  1X11 A;  2Z0O A;  4B6H A;  1ZC3 B;  1MK9 B;  1U5G A;  3PEG A;  4CHJ A;  2M14 A;  1K5D B;  3LJU X;  1NTY A;  1TQZ A;  4A6F A;  2EC1 A;  2MWN B;  2I1J A;  4P7I A;  2DN6 A;  2I5C A;  4XWX A;  2MDX A;  1J19 A;  4NY0 A;  4IOY X;  1BTN A;  1OQN A;  5J3Q A;  2EMT A;  4HB2 B;  1XKE A;  4KHB B;  1W1D A;  1MAI A;  3AU4 A;  1MPH A;  5D3W A;  4CHM A;  4DX8 A;  4BBK A;  3SV1 A;  4HAW B;  3A98 B;  2YSZ A;  5CLL B;  3A8P A;  3KRX A;  1EF1 A;  2YF0 A;  3DXD A;  2YS1 A;  2AL6 A;  1DYN A;  1FGY A;  5LOP B;  4WJ7 A;  2DYQ A;  2Y7B A;  3PZD A;  1U27 A;  3IVF A;  3ODX A;  2X18 A;  1KZ7 A;  4HHV A;  1FOE A;  1UEF A;  5JHH A;  2D9V A;  4PQ0 A;  2COA A;  2D9W A;  2D2Q A;  3P7Z A;  2RNR B;  2VKI A;  2H7D A;  1ZVR A;  3OAN A;  1XR0 B;  2D10 A;  4K81 A;  1FHO A;  1DDV A;  2DFK A;  4IAP A;  2I1K A;  2ZPY A;  1WVH A;  4HB0 B;  2GCJ A;  2D11 A;  3D8E A;  1GC7 A;  3ZVR A;  5C6R A;  2LUL A;  2J0M A;  2D9X A;  4K17 A;  4EMO A;  5D27 A;  1X05 A;  5C79 A;  2R0D A;  1UNQ A;  3RCP A;  1WGU A;  2G35 A;  5HE1 A;  3UZT A;  3ODO A;  1XCG A;  2YVC A;  1DDW A;  5JP4 A;  2ADZ A;  1MK7 B;  2W2W A;  3N7C A;  1BAK A;  3KSY A;  3ODW A;  3ZDT A;  3CXB B;  3ULC A;  5FI1 A;  1X1F A;  2IYB A;  4HAT B;  2DYN A;  4Z2M B;  2JP2 A;  2GJY A;  2COC A;  2P0D A;  1SHC A;  1LW3 A;  1FAO A;  4TYZ A;  2EJ8 A;  3PG7 A;  2RVB B;  1WI1 A;  3SYX A;  1P5T A;  2BCJ A;  2I5F A;  5C16 A;  4HB3 B;  1UNR A;  3NSU A;  2YT1 A;  1XD4 A;  4GMV A;  1MKE A;  2R09 A;  4A6K A;  1FGZ A;  1V5U A;  2PZ1 A;  1XX0 A;  4ZRK A;  1GC6 A;  3SUZ A;  2ROV A;  4NSW A;  5HE0 A;  2DHI A;  1H4R A;  1FHW A;  3X23 A;  4DBB A;  5DIF B;  1EGX A;  4DXA B;  2QKM A;  2VSZ A;  3A8Q A;  1PLS A;  4CYE A;  2LYD A;  2P0F A;  2UZS A;  2W2X C;  2CRF A;  1N3H A;  3V5W A;  3TVV A;  3WA0 A;  3F5R A;  5C5B B;  4HAV B;  3PSC A;  1X1G A;  1MIX A;  1Q67 A;  5KQ1 A;  4PNK A;  3DXE A;  2N0Y A;  3HQC A;  3BIN A;  2Q13 A;  3QIJ A;  3KY9 A;  3QWM A;  1W1H A;  2N23 A;  2ELA A;  2IFS A;  4KAX B;  2YRY A;  3PVL A;  4HB4 B;  1DDM A;  1J0W A;  1ZC4 B;  2DKQ A;  2MKR A;  2UZR A;  3U7D A;  4TKN A;  5LON B;  2AEH A;  2DX5 A;  3CIK A;  4WVF B;  1M7R A;  2K2J A;  3GYO A;  3DXC A;  1KZG A;  1V89 A;  5J3T A;  2KUP A;  1PFJ A;  2RLO A;  2YT0 A;  2YS3 A;  1I2H A;  1BWN A;  4KHA A;  3TCA A;  2H7E A;  3MDB C;  2Y8F A;  1KI1 B;  5C5B A;  1OMW A;  1E5W A;  3TO1 A;  4YON A;  3QBV B;  1ZM0 A;  5CLQ B;  5J3Y A;  2RSG A;  4A6H A;  1V88 A;  2ELB A;  2LOZ A;  3VIA A;  2E2X A;  4YL8 A;  5FI0 A;  2DTC A;  3HK0 A;  4L6E A;  1B55 A;  2UVM A;  4F7H A;  1NU2 A;  4Y94 A;  3FEH A;  3ULB A;  1V5P A;  5D3V A;  2Z0Q A;  2QKL A;  1U2B A;  2P0H A;  1U5D A;  2FJL A;  3G9W A;  2CY5 A;  4GN1 A;  4EKU A;  2COD A;  2J59 M;  1QQG A;  3D8D A;  1Y19 B;  1RRP B;  3P6A A;  2NZ8 B;  1NTV A;  1FB8 A;  2DX1 A;  3VOQ A;  3PVU A;  2DKP A;  2CAY A;  1ZSQ A;  2DLW A;  3MPX A;  5L81 A;  2GCL A;  3GYP A;  1EVH A;  5DHF B;  1MIZ B;  1SGH A;  1RJ2 A;  4F7G A;  3KZ1 A;  4EJN A;  1BTK A;  5JLJ B;  3PVW A;  2RGN B;  1WGQ A;  1UNP A;  4IFS A;  2D9Y A;  1XOD A;  2XQN M;  5DH9 B;  2M38 A;  2DA0 A;  2YS5 A;  1P6S A;  4F7U P;  1I7A A;  4MY6 A;  5KQ4 A;  5HE3 A;  2L2I A;  4MT7 A;  2EMS A;  1EAZ A;  3HW2 B;  1PMS A;  4Z2N A;  2P8V A;  3FM8 C;  1U5E A;  1OY2 A;  1P3R A;  4GZU A;  5GOW B;  2J0J A;  2LKO A;  4K2O A;  4HAX B;  2GS0 A;  2DHK A;  4HDO A;  2K00 A;  4K2P A;  1IRS A;  2V76 A;  1WJ1 A;  3O96 A;  4KVG B;  1U29 A;  1DRO A;  4H8S A;  1U5F A;  3KRW A;  2DHJ A;  1GG3 A;  4HDQ A;  1NI2 A;  2OTX A;  3TFM A;  5DHA B;  2RUK B;  2COF A;  2W2X D;  5KCV A;  2MFQ A;  2KGX B;  4ZRI A;  3TW1 A;  2K2U A;  4GXB A;  3ML4 A;  2HTH B;  3SO6 A;  1UPQ A;  4HAY B;  2LOX A;  1V5M A;  2Z0P A;  4ZRJ A;  1Z87 A;  1W1G A;  2ROZ B;  3D8F A;  4WSF A;  1FHX A;  2LG1 A;  2NMB A;  4GMX B;  3FSS A; 
#chains in the Genus database with same CATH topology
 2KIG A;  4KHO A;  4MK0 A;  4OT1 A;  4A6F B;  4D0N B;  1TXD A;  1ISN A;  3OHM B;  2KCJ A;  1AWE A;  1QC6 A;  3AJ4 A;  3SNH A;  3T06 A;  5D3X A;  2D9Z A;  5HE2 A;  4DX9 0;  3WYF B;  2D4Q A;  1V61 A;  1DBH A;  1LB1 A;  2Y8G A;  2CY4 A;  4HAZ B;  1AQC A;  3PP2 A;  1H10 A;  2VRW B;  3M1I B;  4A5K A;  2HE7 A;  5JHG A;  5I2S A;  1X86 A;  2J0K A;  3AU5 A;  2RRF A;  4CSQ A;  3F0W A;  1WJM A;  5DI9 B;  4GPT B;  3U8Z A;  2OQB A;  1UPR A;  3BJI A;  4C0A A;  1M7E A;  1K5G B;  2L1C A;  1Y5O A;  1WG7 A;  5EFX A;  1TJ6 A;  3A58 A;  4HAU B;  5D3Y A;  1X11 A;  2Z0O A;  4B6H A;  1ZC3 B;  1MK9 B;  1U5G A;  3PEG A;  4CHJ A;  2M14 A;  1K5D B;  3LJU X;  1NTY A;  1TQZ A;  4A6F A;  2EC1 A;  2MWN B;  2I1J A;  4QJ4 B;  4P7I A;  2DN6 A;  2I5C A;  4XWX A;  1ZYI A;  2MDX A;  1J19 A;  4NY0 A;  4IOY X;  1BTN A;  4D6W A;  1OQN A;  5J3Q A;  2EMT A;  4HB2 B;  1XKE A;  4KHB B;  1W1D A;  1MAI A;  3AU4 A;  1MPH A;  5D3W A;  4CHM A;  4DX8 A;  4BBK A;  2R2Y A;  3SV1 A;  3B77 A;  4HAW B;  3A98 B;  2YSZ A;  5CLL B;  3A8P A;  3KRX A;  1EF1 A;  5IRS A;  2YF0 A;  3DXD A;  3NW8 A;  2YS1 A;  2AL6 A;  1DYN A;  1FGY A;  5LOP B;  4WJ7 A;  2DYQ A;  2Y7B A;  3PZD A;  1U27 A;  3IVF A;  3ODX A;  2X18 A;  1KZ7 A;  4HHV A;  1FOE A;  1UEF A;  5JHH A;  2D9V A;  4PQ0 A;  2COA A;  2D9W A;  2D2Q A;  3P7Z A;  2RNR B;  2VKI A;  2H7D A;  1ZVR A;  3OAN A;  1XR0 B;  2D10 A;  4K81 A;  1FHO A;  1DDV A;  2KIE A;  2DFK A;  4IAP A;  2I1K A;  2ZPY A;  1WVH A;  4HB0 B;  2GCJ A;  2D11 A;  3D8E A;  1GC7 A;  3ZVR A;  5C6R A;  4QJ3 B;  4KHB A;  2LUL A;  2J0M A;  2D9X A;  3HIE A;  4K17 A;  4EMO A;  5D27 A;  1X05 A;  5C79 A;  2R0D A;  1UNQ A;  3RCP A;  1WGU A;  2G35 A;  5HE1 A;  3UZT A;  3ODO A;  1XCG A;  2YVC A;  1DDW A;  5JP4 A;  2ADZ A;  1MK7 B;  2W2W A;  3N7C A;  1BAK A;  3KSY A;  3ODW A;  3ZDT A;  3CXB B;  3ULC A;  5FI1 A;  1X1F A;  2IYB A;  3U12 A;  2GUM A;  4HAT B;  2FJU B;  2DYN A;  4Z2M B;  2JP2 A;  5M4Y B;  2Z59 A;  2GJY A;  2COC A;  2P0D A;  1SHC A;  1LW3 A;  1FAO A;  4TYZ A;  2EJ8 A;  3PG7 A;  2RVB B;  1T77 A;  1WI1 A;  3SYX A;  1P5T A;  2Z13 A;  2BCJ A;  2I5F A;  5C16 A;  4HB3 B;  1UNR A;  3NSU A;  3HSA A;  2YT1 A;  1XD4 A;  4GMV A;  1MKE A;  2R09 A;  4A6K A;  1FGZ A;  1V5U A;  2PZ1 A;  1XX0 A;  4ZRK A;  1GC6 A;  3SUZ A;  2ROV A;  4NSW A;  5HE0 A;  2DHI A;  1H4R A;  1FHW A;  4L1R A;  2ZKM X;  3X23 A;  4DBB A;  5DIF B;  1EGX A;  4DXA B;  2QKM A;  2VSZ A;  3A8Q A;  1PLS A;  2K8E A;  4CYE A;  2LYD A;  2P0F A;  2UZS A;  2W2X C;  2CRF A;  1N3H A;  3V5W A;  3TVV A;  3WA0 A;  3F5R A;  5C5B B;  4HAV B;  3PSC A;  1X1G A;  1MIX A;  1Q67 A;  5KQ1 A;  4PNK A;  3DXE A;  2N0Y A;  3HQC A;  3BIN A;  2Q13 A;  3QIJ A;  4GNK B;  3KY9 A;  3QWM A;  1W1H A;  2N23 A;  2ELA A;  2IFS A;  4KAX B;  2YRY A;  3PVL A;  4HB4 B;  1DDM A;  1J0W A;  1ZC4 B;  2DKQ A;  2MKR A;  2UZR A;  3U7D A;  4TKN A;  4HSI A;  5LON B;  2AEH A;  2DX5 A;  3CIK A;  4WVF B;  1M7R A;  2K2J A;  3GYO A;  1MI1 A;  3DXC A;  1KZG A;  1V89 A;  5J3T A;  4DIX A;  2KUP A;  1PFJ A;  2RLO A;  2YT0 A;  2YS3 A;  1I2H A;  1BWN A;  4KHA A;  3TCA A;  2H7E A;  3DCX A;  3MDB C;  2Y8F A;  1KI1 B;  5C5B A;  1OMW A;  1E5W A;  3TO1 A;  4YON A;  3QBV B;  1ZM0 A;  5CLQ B;  5J3Y A;  2RSG A;  4A6H A;  1V88 A;  2ELB A;  2LOZ A;  3FVC A;  3VIA A;  2E2X A;  4YL8 A;  5FI0 A;  2DTC A;  4OSN A;  3HK0 A;  3NWA A;  1B55 A;  2UVM A;  4L6E A;  4F7H A;  1NU2 A;  4Y94 A;  3FEH A;  3ULB A;  1V5P A;  5D3V A;  2Z0Q A;  2QKL A;  1U2B A;  2P0H A;  1U5D A;  2Z14 A;  2FJL A;  3G9W A;  2CY5 A;  4GN1 A;  4EKU A;  2COD A;  2J59 M;  1QQG A;  3D8D A;  1Y19 B;  1RRP B;  2K49 A;  3P6A A;  2NZ8 B;  1NTV A;  5I2M A;  1FB8 A;  2DX1 A;  3VOQ A;  3PVU A;  2DKP A;  2CAY A;  1ZSQ A;  2DLW A;  3MPX A;  5L81 A;  2GCL A;  3GYP A;  1EVH A;  3NWF A;  5DHF B;  1MIZ B;  1SGH A;  1RJ2 A;  4F7G A;  3KZ1 A;  4EJN A;  1BTK A;  5JLJ B;  3PVW A;  2RGN B;  1WGQ A;  1UNP A;  4IFS A;  2D9Y A;  1XOD A;  2XQN M;  5DH9 B;  2M38 A;  2DA0 A;  2YS5 A;  1P6S A;  3NWD A;  4F7U P;  1I7A A;  4MY6 A;  5KQ4 A;  5HE3 A;  2L2I A;  4MT7 A;  2EMS A;  1EAZ A;  3HW2 B;  1PMS A;  2YT2 A;  4Z2N A;  2P8V A;  3FM8 C;  1U5E A;  1OY2 A;  4QJ5 B;  1P3R A;  4GZU A;  5GOW B;  2J0J A;  2LKO A;  4K2O A;  2Z4D A;  4HAX B;  2GS0 A;  2DHK A;  4HDO A;  2K00 A;  4QXA B;  4K2P A;  1IRS A;  2V76 A;  1WJ1 A;  3O96 A;  4KVG B;  1U29 A;  1DRO A;  2KUQ A;  4H8S A;  1U5F A;  3KRW A;  2DHJ A;  1GG3 A;  4HDQ A;  1NI2 A;  2OTX A;  3TFM A;  5DHA B;  2RUK B;  2COF A;  2W2X D;  5KCV A;  2MFQ A;  2KGX B;  4ZRI A;  4GOU A;  3TW1 A;  2K2U A;  4GXB A;  3ML4 A;  2HTH B;  2KR0 A;  3SO6 A;  1UPQ A;  4HAY B;  2LOX A;  1V5M A;  2Z0P A;  4ZRJ A;  1Z87 A;  5LG4 B;  1W1G A;  2ROZ B;  3D8F A;  4WSF A;  2NBV A;  1FHX A;  2LG1 A;  2NMB A;  4GMX B;  3FSS A; 
#chains in the Genus database with same CATH homology
 4KHO A;  4MK0 A;  4A6F B;  4D0N B;  1TXD A;  1ISN A;  2KCJ A;  1AWE A;  1QC6 A;  3AJ4 A;  3SNH A;  3T06 A;  5D3X A;  2D9Z A;  5HE2 A;  4DX9 0;  3WYF B;  2D4Q A;  1V61 A;  1DBH A;  1LB1 A;  2Y8G A;  2CY4 A;  4HAZ B;  1AQC A;  3PP2 A;  1H10 A;  2VRW B;  3M1I B;  4A5K A;  2HE7 A;  5JHG A;  1X86 A;  2J0K A;  3AU5 A;  3F0W A;  1WJM A;  5DI9 B;  4GPT B;  3U8Z A;  2OQB A;  1UPR A;  3BJI A;  4C0A A;  1M7E A;  1K5G B;  2L1C A;  1Y5O A;  1WG7 A;  5EFX A;  1TJ6 A;  4HAU B;  5D3Y A;  1X11 A;  2Z0O A;  4B6H A;  1ZC3 B;  1MK9 B;  1U5G A;  3PEG A;  4CHJ A;  2M14 A;  1K5D B;  3LJU X;  1NTY A;  1TQZ A;  4A6F A;  2EC1 A;  2MWN B;  2I1J A;  4P7I A;  2DN6 A;  2I5C A;  4XWX A;  2MDX A;  1J19 A;  4NY0 A;  4IOY X;  1BTN A;  1OQN A;  5J3Q A;  2EMT A;  4HB2 B;  1XKE A;  4KHB B;  1W1D A;  1MAI A;  3AU4 A;  1MPH A;  5D3W A;  4CHM A;  4DX8 A;  4BBK A;  3SV1 A;  4HAW B;  3A98 B;  2YSZ A;  5CLL B;  3A8P A;  3KRX A;  1EF1 A;  2YF0 A;  3DXD A;  2YS1 A;  2AL6 A;  1DYN A;  1FGY A;  5LOP B;  4WJ7 A;  2DYQ A;  2Y7B A;  3PZD A;  1U27 A;  3IVF A;  3ODX A;  2X18 A;  1KZ7 A;  4HHV A;  1FOE A;  1UEF A;  5JHH A;  2D9V A;  4PQ0 A;  2COA A;  2D9W A;  2D2Q A;  3P7Z A;  2RNR B;  2VKI A;  2H7D A;  1ZVR A;  3OAN A;  1XR0 B;  2D10 A;  4K81 A;  1FHO A;  1DDV A;  2DFK A;  4IAP A;  2I1K A;  2ZPY A;  1WVH A;  4HB0 B;  2GCJ A;  2D11 A;  3D8E A;  1GC7 A;  3ZVR A;  5C6R A;  2LUL A;  2J0M A;  2D9X A;  4K17 A;  4EMO A;  5D27 A;  1X05 A;  5C79 A;  2R0D A;  1UNQ A;  3RCP A;  1WGU A;  2G35 A;  5HE1 A;  3UZT A;  3ODO A;  1XCG A;  2YVC A;  1DDW A;  5JP4 A;  2ADZ A;  1MK7 B;  2W2W A;  3N7C A;  1BAK A;  3KSY A;  3ODW A;  3ZDT A;  3CXB B;  3ULC A;  5FI1 A;  1X1F A;  2IYB A;  4HAT B;  2DYN A;  4Z2M B;  2JP2 A;  2GJY A;  2COC A;  2P0D A;  1SHC A;  1LW3 A;  1FAO A;  4TYZ A;  2EJ8 A;  3PG7 A;  2RVB B;  1WI1 A;  3SYX A;  1P5T A;  2BCJ A;  2I5F A;  5C16 A;  4HB3 B;  1UNR A;  3NSU A;  2YT1 A;  1XD4 A;  4GMV A;  1MKE A;  2R09 A;  4A6K A;  1FGZ A;  1V5U A;  2PZ1 A;  1XX0 A;  4ZRK A;  1GC6 A;  3SUZ A;  2ROV A;  4NSW A;  5HE0 A;  2DHI A;  1H4R A;  1FHW A;  3X23 A;  4DBB A;  5DIF B;  1EGX A;  4DXA B;  2QKM A;  2VSZ A;  3A8Q A;  1PLS A;  4CYE A;  2LYD A;  2P0F A;  2UZS A;  2W2X C;  2CRF A;  1N3H A;  3V5W A;  3TVV A;  3WA0 A;  3F5R A;  5C5B B;  4HAV B;  3PSC A;  1X1G A;  1MIX A;  1Q67 A;  5KQ1 A;  4PNK A;  3DXE A;  2N0Y A;  3HQC A;  3BIN A;  2Q13 A;  3QIJ A;  3KY9 A;  3QWM A;  1W1H A;  2N23 A;  2ELA A;  2IFS A;  4KAX B;  2YRY A;  3PVL A;  4HB4 B;  1DDM A;  1J0W A;  1ZC4 B;  2DKQ A;  2MKR A;  2UZR A;  3U7D A;  4TKN A;  5LON B;  2AEH A;  2DX5 A;  3CIK A;  4WVF B;  1M7R A;  2K2J A;  3GYO A;  3DXC A;  1KZG A;  1V89 A;  5J3T A;  2KUP A;  1PFJ A;  2RLO A;  2YT0 A;  2YS3 A;  1I2H A;  1BWN A;  4KHA A;  3TCA A;  2H7E A;  3MDB C;  2Y8F A;  1KI1 B;  5C5B A;  1OMW A;  1E5W A;  3TO1 A;  4YON A;  3QBV B;  1ZM0 A;  5CLQ B;  5J3Y A;  2RSG A;  4A6H A;  1V88 A;  2ELB A;  2LOZ A;  3VIA A;  2E2X A;  4YL8 A;  5FI0 A;  2DTC A;  3HK0 A;  4L6E A;  1B55 A;  2UVM A;  4F7H A;  1NU2 A;  4Y94 A;  3FEH A;  3ULB A;  1V5P A;  5D3V A;  2Z0Q A;  2QKL A;  1U2B A;  2P0H A;  1U5D A;  2FJL A;  3G9W A;  2CY5 A;  4GN1 A;  4EKU A;  2COD A;  2J59 M;  1QQG A;  3D8D A;  1Y19 B;  1RRP B;  3P6A A;  2NZ8 B;  1NTV A;  1FB8 A;  2DX1 A;  3VOQ A;  3PVU A;  2DKP A;  2CAY A;  1ZSQ A;  2DLW A;  3MPX A;  5L81 A;  2GCL A;  3GYP A;  1EVH A;  5DHF B;  1MIZ B;  1SGH A;  1RJ2 A;  4F7G A;  3KZ1 A;  4EJN A;  1BTK A;  5JLJ B;  3PVW A;  2RGN B;  1WGQ A;  1UNP A;  4IFS A;  2D9Y A;  1XOD A;  2XQN M;  5DH9 B;  2M38 A;  2DA0 A;  2YS5 A;  1P6S A;  4F7U P;  1I7A A;  4MY6 A;  5KQ4 A;  5HE3 A;  2L2I A;  4MT7 A;  2EMS A;  1EAZ A;  3HW2 B;  1PMS A;  4Z2N A;  2P8V A;  3FM8 C;  1U5E A;  1OY2 A;  1P3R A;  4GZU A;  5GOW B;  2J0J A;  2LKO A;  4K2O A;  4HAX B;  2GS0 A;  2DHK A;  4HDO A;  2K00 A;  4K2P A;  1IRS A;  2V76 A;  1WJ1 A;  3O96 A;  4KVG B;  1U29 A;  1DRO A;  4H8S A;  1U5F A;  3KRW A;  2DHJ A;  1GG3 A;  4HDQ A;  1NI2 A;  2OTX A;  3TFM A;  5DHA B;  2RUK B;  2COF A;  2W2X D;  5KCV A;  2MFQ A;  2KGX B;  4ZRI A;  3TW1 A;  2K2U A;  4GXB A;  3ML4 A;  2HTH B;  3SO6 A;  1UPQ A;  4HAY B;  2LOX A;  1V5M A;  2Z0P A;  4ZRJ A;  1Z87 A;  1W1G A;  2ROZ B;  3D8F A;  4WSF A;  1FHX A;  2LG1 A;  2NMB A;  4GMX B;  3FSS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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