1QUBA

Crystal structure of the glycosylated five-domain human beta2-glycoprotein i purified from blood plasma
Total Genus 53
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
319
structure length
319
Chain Sequence
GRTCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPRVCPFAGILENGAVRYTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTKLPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSAMPSCKASCKVPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTEDAQCIDGTIEVPKCFKEHTDASDVKPC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Adhesion mechanism of human beta(2)-glycoprotein I to phospholipids based on its crystal structure.
pubmed doi rcsb
molecule tags Membrane adhesion
molecule keywords PROTEIN (human beta2-Glycoprotein I)
total genus 53
structure length 319
sequence length 319
ec nomenclature
pdb deposition date 1999-07-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00084 Sushi Sushi repeat (SCR repeat)
A PF09014 Sushi_2 Beta-2-glycoprotein-1 fifth domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1qubA04
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1qubA02
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1qubA01
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1qubA03
2.10.70.10 Mainly Beta Ribbon Complement Module; domain 1 Complement Module, domain 1 1qubA05
1Q3XA 1UOTP 4YNXA 3R62A 1OK9A 3RJ3D 2RLPA 1H04P 1Z92B 1FBRA 2XWJI 2YBYA 3OXUD 3NFPI 5HZPB 4IGDA 4LOTA 2RKYA 3KXVA 3M7PA 2IZ4A 2XRDA 4F4OC 1VVCA 3T5OA 1OJWA 1CKLA 1MD7A 3IX0A 1ZJKA 4LOSA 4AYDA 2LOJA 2RKZA 1QUBA 1GKGA 1QGBA 1SS2A 1OJYA 1PPQA 1GHQB 4WJG2 2MCZA 1TPNA 1HCCA 4J38B 1MD8A 2RLQA 5HYUB 4ONTD 2JGWA 2YRAA 1HFIA 1E88A 2WIIC 3IU3I 1LY2A 4FXGG 2XQWC 2KMSA 4B2SA 3GXEA 3EJHA 2EC3A 2W80A 2QY0A 1O9AA 2UWNA 2MCYA 1C1ZA 3L89M 4AYIA 2EHFA 4ZH1D 1H2QP 1VVDA 2JRAA 4C16A 2RL0A 5JPMG 2G7IA 3INBC 5FO8C 4AYEA 2JGXA 2A55A 4JHSA 2XRBA 4AYMA 4PZ5A 3ZRZA 5HYTB 1TPMA 3OP8A 1OK2A 3ZD2A 1GPZA 2ERJA 2KRIA 3CALA 5I0QB 2BZMA 2O39C 2IZ3A 4MUCA 4KKDA 2CG6A 4B2RA 3GOVA 1U5MA 1OK3A 1H03P 1OK1A 3O8EB 1H2PP 1G4FA 1ELVA 5HYPA 1E8BA 1OJVA 1QO6A 2XWBF 4A5WB 3ERBA 2B5ID 3KZJA 4DJZA 1E5GA 1NWVA 3OEDC 4K12A 3ZD1A 1GKNA 2W81A 1TPGA 1G4GA 2CKUA 3TVJA 4CSYA 1SRZA 1HFHA 2V8EA 3SW0X 2CG7A 3MQLA
chains in the Genus database with same CATH superfamily
1Q3XA 1UOTP 4YNXA 3R62A 1OK9A 3RJ3D 2RLPA 1H04P 1Z92B 1FBRA 2XWJI 2YBYA 3OXUD 3NFPI 5HZPB 4IGDA 4LOTA 2RKYA 3KXVA 3M7PA 3K3TA 2IZ4A 2XRDA 3WSXA 4F4OC 1VVCA 3NJAA 3T5OA 1OJWA 1CKLA 1MD7A 3IX0A 1ZJKA 4LOSA 4AYDA 2LOJA 4N7EA 2RKZA 1QUBA 1GKGA 1QGBA 1SS2A 1OJYA 1PPQA 1GHQB 4WJG2 2MCZA 3FGRA 1TPNA 1HCCA 4J38B 1MD8A 1RLHA 2RLQA 5HYUB 3FGTA 4ONTD 2JGWA 2YRAA 1HFIA 2ZYCA 1E88A 2WIIC 3IU3I 1LY2A 4FXGG 2XQWC 2KMSA 4B2SA 2Y8RA 3GXEA 3EJHA 2EC3A 2W80A 2QY0A 1O9AA 2UWNA 4APLA 2MCYA 1C1ZA 3L89M 4AYIA 2EHFA 4ZH1D 1H2QP 3ZLDA 1VVDA 4YIZA 5DN5A 2JRAA 3ZLEA 2RL0A 4C16A 5JPMG 2G7IA 3INBC 5DN4A 5FO8C 4AYEA 3F6KA 2JGXA 2A55A 4JHSA 2XRBA 4AYMA 4PZ5A 3ZRZA 5HYTB 1TPMA 3OP8A 1OK2A 3ZD2A 1GPZA 2ERJA 2KRIA 3CALA 5I0QB 2BZMA 2O39C 2IZ3A 4MUCA 4KKDA 3WSYA 2CG6A 4B2RA 3GOVA 1U5MA 3CI0J 3VWOA 1OK3A 2Y8TA 4MSLA 1H03P 1OK1A 3O8EB 1H2PP 2I2LA 1G4FA 1ELVA 5HYPA 1E8BA 2X2ZA 4BWCA 1OJVA 1QO6A 2XWBF 4A5WB 3ERBA 2B5ID 2Y8SA 3KZJA 4DJZA 1E5GA 1NWVA 3OEDC 4K12A 3ZD1A 1GKNA 2W81A 1TPGA 1G4GA 2CKUA 3TVJA 4CSYA 1SRZA 4PO7A 1HFHA 2V8EA 3SW0X 2CG7A 3MQLA
chains in the Genus database with same CATH topology
1Q3XA 1UOTP 4YNXA 3R62A 1OK9A 3RJ3D 2RLPA 1H04P 1Z92B 1FBRA 2XWJI 2YBYA 3OXUD 3NFPI 5HZPB 4IGDA 4LOTA 2RKYA 3KXVA 3M7PA 2IZ4A 2XRDA 4F4OC 1VVCA 3T5OA 1OJWA 1CKLA 1MD7A 3IX0A 1ZJKA 4LOSA 4AYDA 2LOJA 2RKZA 1QUBA 1GKGA 1QGBA 1SS2A 1OJYA 1PPQA 1GHQB 4WJG2 2MCZA 1TPNA 1HCCA 4J38B 1MD8A 2RLQA 5HYUB 4ONTD 2JGWA 2YRAA 1HFIA 1E88A 2WIIC 3IU3I 1LY2A 4FXGG 2XQWC 2KMSA 4B2SA 3GXEA 3EJHA 2EC3A 2W80A 2QY0A 1O9AA 2UWNA 2MCYA 1C1ZA 3L89M 4AYIA 2EHFA 4ZH1D 1H2QP 1VVDA 2JRAA 4C16A 2RL0A 5JPMG 2G7IA 3INBC 5FO8C 4AYEA 2JGXA 2A55A 4JHSA 2XRBA 4AYMA 4PZ5A 3ZRZA 5HYTB 1TPMA 3OP8A 1OK2A 3ZD2A 1GPZA 2ERJA 2KRIA 3CALA 5I0QB 2BZMA 2O39C 2IZ3A 4MUCA 4KKDA 2CG6A 4B2RA 3GOVA 1U5MA 1OK3A 1H03P 1OK1A 3O8EB 1H2PP 1G4FA 1ELVA 5HYPA 1E8BA 1OJVA 1QO6A 2XWBF 4A5WB 3ERBA 2B5ID 3KZJA 4DJZA 1E5GA 1NWVA 3OEDC 4K12A 3ZD1A 1GKNA 2W81A 1TPGA 1G4GA 2CKUA 3TVJA 4CSYA 1SRZA 1HFHA 2V8EA 3SW0X 2CG7A 3MQLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Q3X A;  1UOT P;  4YNX A;  3R62 A;  1OK9 A;  3RJ3 D;  2RLP A;  1H04 P;  1Z92 B;  1FBR A;  2XWJ I;  2YBY A;  3OXU D;  3NFP I;  5HZP B;  4IGD A;  4LOT A;  2RKY A;  3KXV A;  3M7P A;  2IZ4 A;  2XRD A;  4F4O C;  1VVC A;  3T5O A;  1OJW A;  1CKL A;  1MD7 A;  3IX0 A;  1ZJK A;  4LOS A;  4AYD A;  2LOJ A;  2RKZ A;  1QUB A;  1GKG A;  1QGB A;  1SS2 A;  1OJY A;  1PPQ A;  1GHQ B;  4WJG 2;  2MCZ A;  1TPN A;  1HCC A;  4J38 B;  1MD8 A;  2RLQ A;  5HYU B;  4ONT D;  2JGW A;  2YRA A;  1HFI A;  1E88 A;  2WII C;  3IU3 I;  1LY2 A;  4FXG G;  2XQW C;  2KMS A;  4B2S A;  3GXE A;  3EJH A;  2EC3 A;  2W80 A;  2QY0 A;  1O9A A;  2UWN A;  2MCY A;  1C1Z A;  3L89 M;  4AYI A;  2EHF A;  4ZH1 D;  1H2Q P;  1VVD A;  2JRA A;  4C16 A;  2RL0 A;  5JPM G;  2G7I A;  3INB C;  5FO8 C;  4AYE A;  2JGX A;  2A55 A;  4JHS A;  2XRB A;  4AYM A;  4PZ5 A;  3ZRZ A;  5HYT B;  1TPM A;  3OP8 A;  1OK2 A;  3ZD2 A;  1GPZ A;  2ERJ A;  2KRI A;  3CAL A;  5I0Q B;  2BZM A;  2O39 C;  2IZ3 A;  4MUC A;  4KKD A;  2CG6 A;  4B2R A;  3GOV A;  1U5M A;  1OK3 A;  1H03 P;  1OK1 A;  3O8E B;  1H2P P;  1G4F A;  1ELV A;  5HYP A;  1E8B A;  1OJV A;  1QO6 A;  2XWB F;  4A5W B;  3ERB A;  2B5I D;  3KZJ A;  4DJZ A;  1E5G A;  1NWV A;  3OED C;  4K12 A;  3ZD1 A;  1GKN A;  2W81 A;  1TPG A;  1G4G A;  2CKU A;  3TVJ A;  4CSY A;  1SRZ A;  1HFH A;  2V8E A;  3SW0 X;  2CG7 A;  3MQL A; 
#chains in the Genus database with same CATH topology
 1Q3X A;  1UOT P;  4YNX A;  3R62 A;  1OK9 A;  3RJ3 D;  2RLP A;  1H04 P;  1Z92 B;  1FBR A;  2XWJ I;  2YBY A;  3OXU D;  3NFP I;  5HZP B;  4IGD A;  4LOT A;  2RKY A;  3KXV A;  3M7P A;  3K3T A;  2IZ4 A;  2XRD A;  3WSX A;  4F4O C;  1VVC A;  3NJA A;  3T5O A;  1OJW A;  1CKL A;  1MD7 A;  3IX0 A;  1ZJK A;  4LOS A;  4AYD A;  2LOJ A;  4N7E A;  2RKZ A;  1QUB A;  1GKG A;  1QGB A;  1SS2 A;  1OJY A;  1PPQ A;  1GHQ B;  4WJG 2;  2MCZ A;  3FGR A;  1TPN A;  1HCC A;  4J38 B;  1MD8 A;  1RLH A;  2RLQ A;  5HYU B;  3FGT A;  4ONT D;  2JGW A;  2YRA A;  1HFI A;  2ZYC A;  1E88 A;  2WII C;  3IU3 I;  1LY2 A;  4FXG G;  2XQW C;  2KMS A;  4B2S A;  2Y8R A;  3GXE A;  3EJH A;  2EC3 A;  2W80 A;  2QY0 A;  1O9A A;  2UWN A;  4APL A;  2MCY A;  1C1Z A;  3L89 M;  4AYI A;  2EHF A;  4ZH1 D;  1H2Q P;  3ZLD A;  1VVD A;  4YIZ A;  5DN5 A;  2JRA A;  3ZLE A;  2RL0 A;  4C16 A;  5JPM G;  2G7I A;  3INB C;  5DN4 A;  5FO8 C;  4AYE A;  3F6K A;  2JGX A;  2A55 A;  4JHS A;  2XRB A;  4AYM A;  4PZ5 A;  3ZRZ A;  5HYT B;  1TPM A;  3OP8 A;  1OK2 A;  3ZD2 A;  1GPZ A;  2ERJ A;  2KRI A;  3CAL A;  5I0Q B;  2BZM A;  2O39 C;  2IZ3 A;  4MUC A;  4KKD A;  3WSY A;  2CG6 A;  4B2R A;  3GOV A;  1U5M A;  3CI0 J;  3VWO A;  1OK3 A;  2Y8T A;  4MSL A;  1H03 P;  1OK1 A;  3O8E B;  1H2P P;  2I2L A;  1G4F A;  1ELV A;  5HYP A;  1E8B A;  2X2Z A;  4BWC A;  1OJV A;  1QO6 A;  2XWB F;  4A5W B;  3ERB A;  2B5I D;  2Y8S A;  3KZJ A;  4DJZ A;  1E5G A;  1NWV A;  3OED C;  4K12 A;  3ZD1 A;  1GKN A;  2W81 A;  1TPG A;  1G4G A;  2CKU A;  3TVJ A;  4CSY A;  1SRZ A;  4PO7 A;  1HFH A;  2V8E A;  3SW0 X;  2CG7 A;  3MQL A; 
#chains in the Genus database with same CATH homology
 1Q3X A;  1UOT P;  4YNX A;  3R62 A;  1OK9 A;  3RJ3 D;  2RLP A;  1H04 P;  1Z92 B;  1FBR A;  2XWJ I;  2YBY A;  3OXU D;  3NFP I;  5HZP B;  4IGD A;  4LOT A;  2RKY A;  3KXV A;  3M7P A;  2IZ4 A;  2XRD A;  4F4O C;  1VVC A;  3T5O A;  1OJW A;  1CKL A;  1MD7 A;  3IX0 A;  1ZJK A;  4LOS A;  4AYD A;  2LOJ A;  2RKZ A;  1QUB A;  1GKG A;  1QGB A;  1SS2 A;  1OJY A;  1PPQ A;  1GHQ B;  4WJG 2;  2MCZ A;  1TPN A;  1HCC A;  4J38 B;  1MD8 A;  2RLQ A;  5HYU B;  4ONT D;  2JGW A;  2YRA A;  1HFI A;  1E88 A;  2WII C;  3IU3 I;  1LY2 A;  4FXG G;  2XQW C;  2KMS A;  4B2S A;  3GXE A;  3EJH A;  2EC3 A;  2W80 A;  2QY0 A;  1O9A A;  2UWN A;  2MCY A;  1C1Z A;  3L89 M;  4AYI A;  2EHF A;  4ZH1 D;  1H2Q P;  1VVD A;  2JRA A;  4C16 A;  2RL0 A;  5JPM G;  2G7I A;  3INB C;  5FO8 C;  4AYE A;  2JGX A;  2A55 A;  4JHS A;  2XRB A;  4AYM A;  4PZ5 A;  3ZRZ A;  5HYT B;  1TPM A;  3OP8 A;  1OK2 A;  3ZD2 A;  1GPZ A;  2ERJ A;  2KRI A;  3CAL A;  5I0Q B;  2BZM A;  2O39 C;  2IZ3 A;  4MUC A;  4KKD A;  2CG6 A;  4B2R A;  3GOV A;  1U5M A;  1OK3 A;  1H03 P;  1OK1 A;  3O8E B;  1H2P P;  1G4F A;  1ELV A;  5HYP A;  1E8B A;  1OJV A;  1QO6 A;  2XWB F;  4A5W B;  3ERB A;  2B5I D;  3KZJ A;  4DJZ A;  1E5G A;  1NWV A;  3OED C;  4K12 A;  3ZD1 A;  1GKN A;  2W81 A;  1TPG A;  1G4G A;  2CKU A;  3TVJ A;  4CSY A;  1SRZ A;  1HFH A;  2V8E A;  3SW0 X;  2CG7 A;  3MQL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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