1R1HA

Structural analysis of neprilysin with various specific and potent inhibitors
Total Genus 272
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
272
sequence length
696
structure length
696
Chain Sequence
GICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Neprilysin
publication title Structural analysis of neprilysin with various specific and potent inhibitors.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase
total genus 272
structure length 696
sequence length 696
ec nomenclature ec 3.4.24.11: Neprilysin.
pdb deposition date 2003-09-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01431 Peptidase_M13 Peptidase family M13
A PF05649 Peptidase_M13_N Peptidase family M13
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1380.10 Mainly Alpha Orthogonal Bundle Neutral endopeptidase; domain 2 Neutral endopeptidase , domain2 1r1hA02
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 1r1hA01
1JKYA 3SHIA 1D7XA 1XUDA 2I47A 2RJQA 1OMJA 4AYKA 3DL1A 4G9LA 3DNGA 4GR0A 1JH1A 4JP4A 5L7FA 2JIHA 4JIJA 4L6TA 1PWUA 3DSLA 2WOAA 2SRTA 3LGPA 2OXZA 2XS4A 1G05A 1SU3A 4H30A 1B8YA 3LJZA 1J7NA 4GUYA 5LABA 4IJOA 2OI0A 2Y6CA 2OXWA 1UEAA 1YP1A 1HFSA 4FVLA 1RM8A 1IACA 3ZUKA 4XBHA 1PWQA 3K7NA 4R3VA 1XFYA 1K7IA 2D1NA 3P1VA 1GE6A 3BA0A 2O3EA 4GQLA 1EUBA 1K7QA 3LKAA 1JANA 5I2ZA 4IN9A 1HV5A 2YB9A 3LK8A 1G9KA 1IAEA 3E8RA 1Y8JA 2MZHA 4I03A 1GE7A 1ZVXA 2Y6DA 3B92A 1BKCA 3LJGA 5D7WA 4DPEA 3WV1A 1R1JA 5BOYA 1SMPA 1USNA 3Q2GA 3F17A 1AF0A 3O64A 3MA2A 1IAAA 1MMQA 1GXDA 3AIGA 1JK3A 3O2XA 2OW2A 1R1HA 3EDIA 3LUNA 4GWNA 3DPEA 1Z3JA 2N8RA 2K9CA 2E3XA 4EFSA 1FM1A 4WKIA 3WV3A 3EDZA 1CXVA 1QIAA 1HOVA 4JPAA 1HY7A 1BSWA 2X3AA 1JAOA 2WO8A 3P24A 1KAPP 4WKEA 1YCMA 1MMBA 3VI1A 5B5OA 5H8XA 2MZEA 2W0DA 4PKQA 3HB2P 1CGLA 3F18A 1SATA 1YQYA 1R55A 3RTSA 1BUDA 1SLMA 3TSKA 5D2BA 4AUOA 2MZIA 2EROA 2AIGP 3OHLA 1XFVA 3HY7A 3KMEA 1BKCE 1OS9A 4GF1A 3V96B 3KWVC 1ATLA 1DMTA 2RJPA 4PKRA 3NX7A 2OZRA 1ZXCA 2XS3A 2W13A 3Q2HA 3AYUA 830CA 3L0TA 1R54A 1ZXVA 3LEAA 1SLNA 4PKSA 1B3DA 1H71P 2OW9A 2JT5A 2Z2DA 1OS2A 5I0LA 5CXAA 3TT4A 1KUKA 2FV5A 1JJ9A 4H1QA 1EAKA 2OVXA 1QJJA 5I43A 966CA 1G12A 1JIWP 5L79A 3ZXHA 1XFZA 2OVZA 4Q1LA 3VTGA 2CKIA 1DTHA 2JSDA 4IUWA 2OW1A 1SRPA 3ZVSA 1I73A 2W15A 1I1IP 1MMPA 1FBLA 2J83A 1KBCA 1BUVM 1PWWA 4JA1A 1PWVA 4J4MA 2D1OA 2J0TA 2QPJA 2A8HA 4H49A 1BM6A 1G49A 2OY2A 1HTDA 4DD8A 5D1SA 4ON1A 3F15A 5D1TA 4PKWA 3EHYA 1IADA 4FXQA 1MMRA 2ERPA 1KUFA 1AKLA 1C7KA 1D8MA 1A85A 4DV8A 2FV9A 4A7BA 1CGEA 4HMAA 2E2DA 2MLSA 4H84A 1FLSA 3HDAP 4DF9A 2HU6A 2CLTA 4PKVA 4L63A 3GBOA 4XM8A 4ZR5A 4JQGA 3B8ZA 1IABA 2W12A 3RTTA 3LQ0A 1A86A 3LMCA 3AYKA 4GWMA 1GKCA 1RMZA 3KMCA 2X7MA 2MLRA 2JT6A 1OO9A 2X3CA 2K2GA 3LUMA 4ILWD 1Y93A 3HBVP 1QUAA 5D3CA 3WV2A 4H82A 1R1IA 2USNA 2JNPA 3EDGA 1XFUA 2W14A 3LE9A 4XCTA 4GR8A 5CUHA 1KUIA 3USNA 1XUCA 1ZP5A 1BQOA 2V4BA 3HYGA 1HFCA 3LIRA 1QICA 1O0QA 4PKUA 3DPFA 1CQRA 1QIBA 1G4KA 3I7IA 2DW1A 1YOUA 2X3BA 1Q3AA 2DDFA 1XURA 5I4OA 1KUHA 1AYKA 456CA 4HX3A 5B5PA 3LJTA 1JAQA 1GO8P 1C8TA 3I7GA 2TCLA 4XM7A 2YIGA 3G5CA 1BZSA 3LILA 3TS4A 1CGFA 1I76A 3LIKA 1CIZA 1IAGA 1EB6A 1CK7A 3G42A 4GR3A 1Y0VA 3KEJA 3TVCA 1UMSA 3N2UA 1ZS0A 2ERQA 4QKZA 2O36A 1GO7P 2WO9A 1BQQM 1OM6A 1PWPA 1O0TA 2OXUA 2DW2A 2POJA 3F1AA 5CZMA 3HBUP 2OY4A 1JAPA 3KECA 3L0VA 5D1UA 1XFWA 2AYKA 3DWBA 3F16A 1BIWA 4H76A 4G0DA 1ASTA 1KUGA 5BOTA 3EDHA 3EWJA 3KRYA 1UTTA 1QJIA 2KRJA 1BKCI 1WNIA 3ELMA 1ROSA 1UMTA 1D5JA 3HY9A 3U1RA 1XFXA 2L0RA 2PJTA 4FU4A 4L19A 4A3WA 3KEKA 1C3IA 4H3XA 1CAQA 4WF6A 1OM7A 3EHXA 1MNCA 1GE5A 2DDYA 4AXQA 2DW0A 3CKIA 1ND1A 3F19A 4H2EA 3B2ZA 4WZVA 5I3MA 5I12A 4FXYP 3UVCA 4AIGA 1ZTQA 4CTHA 1JIZA 3K7LA 3HDBA 4PKTA 1S4BP 3N2VA 2OW0A 1GKDA 4WK7A 4XM6A 3KHIA 1D8FA 1L6JA 1UTZA 5JMYA 3OHOA 1K7GA 5BPAA 1OM8A 3LQBA 4I35A
chains in the Genus database with same CATH superfamily
1JKYA 3SHIA 1D7XA 1XUDA 2I47A 2RJQA 1OMJA 4AYKA 3DL1A 4G9LA 3DNGA 4GR0A 1JH1A 4JP4A 5L7FA 2JIHA 4JIJA 4L6TA 1XAXA 1PWUA 3DSLA 2WOAA 2SRTA 3LGPA 2OXZA 2XS4A 1G05A 1SU3A 4H30A 1B8YA 3LJZA 1J7NA 4GUYA 5LABA 4IJOA 2OI0A 2Y6CA 2OXWA 1UEAA 1YP1A 1HFSA 4FVLA 1RM8A 1IACA 3ZUKA 4XBHA 1PWQA 3K7NA 4R3VA 1XFYA 1K7IA 3DTEA 2D1NA 3P1VA 1GE6A 3BA0A 2O3EA 4GQLA 1EUBA 1K7QA 3LKAA 1JANA 5I2ZA 4IN9A 1HV5A 2YB9A 3LK8A 1OZ9A 1G9KA 1IAEA 3E8RA 1Y8JA 2MZHA 4I03A 1GE7A 1ZVXA 2Y6DA 3B92A 1BKCA 3LJGA 5D7WA 4DPEA 3WV1A 1R1JA 5BOYA 1SMPA 1USNA 3Q2GA 3F17A 1AF0A 3O64A 3MA2A 1IAAA 1MMQA 1GXDA 1XM5A 3AIGA 1JK3A 3O2XA 2OW2A 1R1HA 3EDIA 3LUNA 4GWNA 3DPEA 1Z3JA 2N8RA 2K9CA 2E3XA 4EFSA 1FM1A 4WKIA 3WV3A 3EDZA 1CXVA 1QIAA 1HOVA 4JPAA 1HY7A 1BSWA 3DTKA 2X3AA 1JAOA 2WO8A 3P24A 1KAPP 4WKEA 1YCMA 1MMBA 3VI1A 5B5OA 5H8XA 2MZEA 2W0DA 4PKQA 3HB2P 1CGLA 3F18A 1SATA 1YQYA 1R55A 3RTSA 1BUDA 1SLMA 3TSKA 5D2BA 4AUOA 2MZIA 2EROA 2AIGP 3OHLA 1XFVA 3HY7A 3KMEA 1BKCE 1OS9A 4GF1A 3V96B 3KWVC 1ATLA 1DMTA 2RJPA 4PKRA 3NX7A 2OZRA 1ZXCA 2XS3A 2W13A 3Q2HA 3AYUA 830CA 3L0TA 1R54A 1ZXVA 3LEAA 1TVIA 1SLNA 4PKSA 1B3DA 1H71P 2OW9A 2JT5A 2Z2DA 1OS2A 5I0LA 5CXAA 3TT4A 1KUKA 2FV5A 1JJ9A 4H1QA 1EAKA 2OVXA 1QJJA 5I43A 966CA 1G12A 1JIWP 5L79A 3ZXHA 1XFZA 2OVZA 4Q1LA 3VTGA 2CKIA 1DTHA 2JSDA 4IUWA 2OW1A 1SRPA 3ZVSA 1I73A 2W15A 1I1IP 1MMPA 1FBLA 2J83A 1KBCA 1BUVM 1PWWA 4JA1A 3DTIA 1PWVA 4J4MA 2D1OA 2J0TA 2QPJA 2A8HA 4H49A 1BM6A 1G49A 2OY2A 1HTDA 4DD8A 5D1SA 4ON1A 3F15A 5D1TA 4PKWA 3EHYA 1IADA 4FXQA 1MMRA 2ERPA 1KUFA 1AKLA 1C7KA 1D8MA 1A85A 4DV8A 2FV9A 4A7BA 1CGEA 4HMAA 2E2DA 2MLSA 4H84A 1FLSA 3HDAP 4DF9A 2HU6A 2CLTA 4PKVA 4L63A 3GBOA 4XM8A 4ZR5A 4JQGA 3B8ZA 1IABA 2W12A 3RTTA 3LQ0A 1A86A 3LMCA 3AYKA 4GWMA 1GKCA 1RMZA 3KMCA 2X7MA 2MLRA 2JT6A 1OO9A 2X3CA 2K2GA 3LUMA 4ILWD 1Y93A 4L7AA 3HBVP 1QUAA 5D3CA 3WV2A 4H82A 1R1IA 2USNA 2JNPA 3EDGA 1XFUA 2W14A 3LE9A 4XCTA 4GR8A 5CUHA 1KUIA 3USNA 1XUCA 1ZP5A 1BQOA 2V4BA 3HYGA 1HFCA 3LIRA 1QICA 1O0QA 4PKUA 3DPFA 1CQRA 1QIBA 1G4KA 3I7IA 2DW1A 1YOUA 2X3BA 1Q3AA 2DDFA 1XURA 5I4OA 1KUHA 1AYKA 456CA 4HX3A 5B5PA 3LJTA 1JAQA 1GO8P 1C8TA 3I7GA 2TCLA 4XM7A 2YIGA 3G5CA 1BZSA 3LILA 3TS4A 1CGFA 1I76A 3LIKA 1CIZA 1IAGA 1EB6A 1CK7A 3G42A 4GR3A 1Y0VA 3KEJA 3TVCA 1UMSA 3N2UA 1ZS0A 2ERQA 4QKZA 2O36A 1GO7P 2WO9A 1BQQM 1OM6A 1PWPA 1O0TA 2OXUA 2DW2A 2POJA 3F1AA 5CZMA 3HBUP 2OY4A 1JAPA 3KECA 3L0VA 5D1UA 1XFWA 2AYKA 3DWBA 3F16A 1BIWA 4H76A 4G0DA 1ASTA 1KUGA 5BOTA 3EDHA 3EWJA 3KRYA 1UTTA 1QJIA 2KRJA 1BKCI 1WNIA 3ELMA 1ROSA 1UMTA 1D5JA 3HY9A 2YUFA 3U1RA 1XFXA 2L0RA 2PJTA 4FU4A 4L19A 4A3WA 3KEKA 1C3IA 4H3XA 1CAQA 4WF6A 1OM7A 3EHXA 1MNCA 1GE5A 2DDYA 4AXQA 2DW0A 3CKIA 1ND1A 3F19A 4H2EA 3B2ZA 4WZVA 5I3MA 5I12A 4FXYP 3UVCA 4AIGA 1ZTQA 4CTHA 1JIZA 3K7LA 3HDBA 4PKTA 1S4BP 3N2VA 2OW0A 1GKDA 4WK7A 4XM6A 3KHIA 1D8FA 1L6JA 1UTZA 5JMYA 3OHOA 1K7GA 5BPAA 1OM8A 3LQBA 4I35A
chains in the Genus database with same CATH topology
1JKYA 3SHIA 1D7XA 1XUDA 2I47A 2RJQA 1OMJA 4AYKA 3DL1A 4G9LA 3DNGA 4GR0A 1JH1A 4JP4A 5L7FA 2JIHA 4JIJA 4L6TA 1PWUA 3DSLA 2WOAA 2SRTA 3LGPA 2OXZA 2XS4A 1G05A 1SU3A 4H30A 1B8YA 3LJZA 1J7NA 4GUYA 5LABA 4IJOA 2OI0A 2Y6CA 2OXWA 1UEAA 1YP1A 1HFSA 4FVLA 1RM8A 1IACA 3ZUKA 4XBHA 1PWQA 3K7NA 4R3VA 1XFYA 1K7IA 3DTEA 2D1NA 3P1VA 1GE6A 3BA0A 2O3EA 4GQLA 1EUBA 1K7QA 3LKAA 1JANA 5I2ZA 4IN9A 1HV5A 2YB9A 3LK8A 1G9KA 1IAEA 3E8RA 1Y8JA 2MZHA 4I03A 1GE7A 1ZVXA 2Y6DA 3B92A 1BKCA 3LJGA 5D7WA 4DPEA 3WV1A 1R1JA 5BOYA 1SMPA 1USNA 3Q2GA 3F17A 1AF0A 3O64A 3MA2A 1IAAA 1MMQA 1GXDA 3AIGA 1JK3A 3O2XA 2OW2A 1R1HA 3EDIA 3LUNA 4GWNA 3DPEA 1Z3JA 2N8RA 2K9CA 2E3XA 4EFSA 1FM1A 4WKIA 3WV3A 3EDZA 1CXVA 1QIAA 1HOVA 4JPAA 1HY7A 1BSWA 3DTKA 2X3AA 1JAOA 2WO8A 3P24A 1KAPP 4WKEA 1YCMA 1MMBA 3VI1A 5B5OA 5H8XA 2MZEA 2W0DA 4PKQA 3HB2P 1CGLA 3F18A 1SATA 1YQYA 1R55A 3RTSA 1BUDA 1SLMA 3TSKA 5D2BA 4AUOA 2MZIA 2EROA 2AIGP 3OHLA 1XFVA 3HY7A 3KMEA 1BKCE 1OS9A 4GF1A 3V96B 3KWVC 1ATLA 1DMTA 2RJPA 4PKRA 3NX7A 2OZRA 1ZXCA 2XS3A 2W13A 3Q2HA 3AYUA 830CA 3L0TA 1R54A 1ZXVA 3LEAA 1SLNA 4PKSA 1B3DA 1H71P 2OW9A 2JT5A 2Z2DA 1OS2A 5I0LA 5CXAA 3TT4A 1KUKA 2FV5A 1JJ9A 4H1QA 1EAKA 2OVXA 1QJJA 5I43A 966CA 1G12A 1JIWP 5L79A 3ZXHA 1XFZA 2OVZA 4Q1LA 3VTGA 2CKIA 1DTHA 2JSDA 4IUWA 2OW1A 1SRPA 3ZVSA 1I73A 2W15A 1I1IP 1MMPA 1FBLA 2J83A 1KBCA 1BUVM 1PWWA 4JA1A 3DTIA 1PWVA 4J4MA 2D1OA 2J0TA 2QPJA 2A8HA 4H49A 1BM6A 1G49A 2OY2A 1HTDA 4DD8A 5D1SA 4ON1A 3F15A 5D1TA 4PKWA 3EHYA 1IADA 4FXQA 1MMRA 2ERPA 1KUFA 1AKLA 1C7KA 1D8MA 1A85A 4DV8A 2FV9A 4A7BA 1CGEA 4HMAA 2E2DA 2MLSA 4H84A 1FLSA 3HDAP 4DF9A 2HU6A 2CLTA 4PKVA 4L63A 3GBOA 4XM8A 4ZR5A 4JQGA 3B8ZA 1IABA 2W12A 3RTTA 3LQ0A 1A86A 3LMCA 3AYKA 4GWMA 1GKCA 1RMZA 3KMCA 2X7MA 2MLRA 2JT6A 1OO9A 2X3CA 2K2GA 3LUMA 4ILWD 1Y93A 4L7AA 3HBVP 1QUAA 5D3CA 3WV2A 4H82A 1R1IA 2USNA 2JNPA 3EDGA 1XFUA 2W14A 3LE9A 4XCTA 4GR8A 5CUHA 1KUIA 3USNA 1XUCA 1ZP5A 1BQOA 2V4BA 3HYGA 1HFCA 3LIRA 1QICA 1O0QA 4PKUA 3DPFA 1CQRA 1QIBA 1G4KA 3I7IA 2DW1A 1YOUA 2X3BA 1Q3AA 2DDFA 1XURA 5I4OA 1KUHA 1AYKA 456CA 4HX3A 5B5PA 3LJTA 1JAQA 1GO8P 1C8TA 3I7GA 2TCLA 4XM7A 2YIGA 3G5CA 1BZSA 3LILA 3TS4A 1CGFA 1I76A 3LIKA 1CIZA 1IAGA 1EB6A 1CK7A 3G42A 4GR3A 1Y0VA 3KEJA 3TVCA 1UMSA 3N2UA 1ZS0A 2ERQA 4QKZA 2O36A 1GO7P 2WO9A 1BQQM 1OM6A 1PWPA 1O0TA 2OXUA 2DW2A 2POJA 3F1AA 5CZMA 3HBUP 2OY4A 1JAPA 3KECA 3L0VA 5D1UA 1XFWA 2AYKA 3DWBA 3F16A 1BIWA 4H76A 4G0DA 1ASTA 1KUGA 5BOTA 3EDHA 3EWJA 3KRYA 1UTTA 1QJIA 2KRJA 1BKCI 1WNIA 3ELMA 1ROSA 1UMTA 1D5JA 3HY9A 2YUFA 3U1RA 1XFXA 2L0RA 2PJTA 4FU4A 4L19A 4A3WA 3KEKA 1C3IA 4H3XA 1CAQA 4WF6A 1OM7A 3EHXA 1MNCA 1GE5A 2DDYA 4AXQA 2DW0A 3CKIA 1ND1A 3F19A 4H2EA 3B2ZA 4WZVA 5I3MA 5I12A 4FXYP 3UVCA 4AIGA 1ZTQA 4CTHA 1JIZA 3K7LA 3HDBA 4PKTA 1S4BP 3N2VA 2OW0A 1GKDA 4WK7A 4XM6A 3KHIA 1D8FA 1L6JA 1UTZA 5JMYA 3OHOA 1K7GA 5BPAA 1OM8A 3LQBA 4I35A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JKY A;  3SHI A;  1D7X A;  1XUD A;  2I47 A;  2RJQ A;  1OMJ A;  4AYK A;  3DL1 A;  4G9L A;  3DNG A;  4GR0 A;  1JH1 A;  4JP4 A;  5L7F A;  2JIH A;  4JIJ A;  4L6T A;  1PWU A;  3DSL A;  2WOA A;  2SRT A;  3LGP A;  2OXZ A;  2XS4 A;  1G05 A;  1SU3 A;  4H30 A;  1B8Y A;  3LJZ A;  1J7N A;  4GUY A;  5LAB A;  4IJO A;  2OI0 A;  2Y6C A;  2OXW A;  1UEA A;  1YP1 A;  1HFS A;  4FVL A;  1RM8 A;  1IAC A;  3ZUK A;  4XBH A;  1PWQ A;  3K7N A;  4R3V A;  1XFY A;  1K7I A;  2D1N A;  3P1V A;  1GE6 A;  3BA0 A;  2O3E A;  4GQL A;  1EUB A;  1K7Q A;  3LKA A;  1JAN A;  5I2Z A;  4IN9 A;  1HV5 A;  2YB9 A;  3LK8 A;  1G9K A;  1IAE A;  3E8R A;  1Y8J A;  2MZH A;  4I03 A;  1GE7 A;  1ZVX A;  2Y6D A;  3B92 A;  1BKC A;  3LJG A;  5D7W A;  4DPE A;  3WV1 A;  1R1J A;  5BOY A;  1SMP A;  1USN A;  3Q2G A;  3F17 A;  1AF0 A;  3O64 A;  3MA2 A;  1IAA A;  1MMQ A;  1GXD A;  3AIG A;  1JK3 A;  3O2X A;  2OW2 A;  1R1H A;  3EDI A;  3LUN A;  4GWN A;  3DPE A;  1Z3J A;  2N8R A;  2K9C A;  2E3X A;  4EFS A;  1FM1 A;  4WKI A;  3WV3 A;  3EDZ A;  1CXV A;  1QIA A;  1HOV A;  4JPA A;  1HY7 A;  1BSW A;  2X3A A;  1JAO A;  2WO8 A;  3P24 A;  1KAP P;  4WKE A;  1YCM A;  1MMB A;  3VI1 A;  5B5O A;  5H8X A;  2MZE A;  2W0D A;  4PKQ A;  3HB2 P;  1CGL A;  3F18 A;  1SAT A;  1YQY A;  1R55 A;  3RTS A;  1BUD A;  1SLM A;  3TSK A;  5D2B A;  4AUO A;  2MZI A;  2ERO A;  2AIG P;  3OHL A;  1XFV A;  3HY7 A;  3KME A;  1BKC E;  1OS9 A;  4GF1 A;  3V96 B;  3KWV C;  1ATL A;  1DMT A;  2RJP A;  4PKR A;  3NX7 A;  2OZR A;  1ZXC A;  2XS3 A;  2W13 A;  3Q2H A;  3AYU A;  830C A;  3L0T A;  1R54 A;  1ZXV A;  3LEA A;  1SLN A;  4PKS A;  1B3D A;  1H71 P;  2OW9 A;  2JT5 A;  2Z2D A;  1OS2 A;  5I0L A;  5CXA A;  3TT4 A;  1KUK A;  2FV5 A;  1JJ9 A;  4H1Q A;  1EAK A;  2OVX A;  1QJJ A;  5I43 A;  966C A;  1G12 A;  1JIW P;  5L79 A;  3ZXH A;  1XFZ A;  2OVZ A;  4Q1L A;  3VTG A;  2CKI A;  1DTH A;  2JSD A;  4IUW A;  2OW1 A;  1SRP A;  3ZVS A;  1I73 A;  2W15 A;  1I1I P;  1MMP A;  1FBL A;  2J83 A;  1KBC A;  1BUV M;  1PWW A;  4JA1 A;  1PWV A;  4J4M A;  2D1O A;  2J0T A;  2QPJ A;  2A8H A;  4H49 A;  1BM6 A;  1G49 A;  2OY2 A;  1HTD A;  4DD8 A;  5D1S A;  4ON1 A;  3F15 A;  5D1T A;  4PKW A;  3EHY A;  1IAD A;  4FXQ A;  1MMR A;  2ERP A;  1KUF A;  1AKL A;  1C7K A;  1D8M A;  1A85 A;  4DV8 A;  2FV9 A;  4A7B A;  1CGE A;  4HMA A;  2E2D A;  2MLS A;  4H84 A;  1FLS A;  3HDA P;  4DF9 A;  2HU6 A;  2CLT A;  4PKV A;  4L63 A;  3GBO A;  4XM8 A;  4ZR5 A;  4JQG A;  3B8Z A;  1IAB A;  2W12 A;  3RTT A;  3LQ0 A;  1A86 A;  3LMC A;  3AYK A;  4GWM A;  1GKC A;  1RMZ A;  3KMC A;  2X7M A;  2MLR A;  2JT6 A;  1OO9 A;  2X3C A;  2K2G A;  3LUM A;  4ILW D;  1Y93 A;  3HBV P;  1QUA A;  5D3C A;  3WV2 A;  4H82 A;  1R1I A;  2USN A;  2JNP A;  3EDG A;  1XFU A;  2W14 A;  3LE9 A;  4XCT A;  4GR8 A;  5CUH A;  1KUI A;  3USN A;  1XUC A;  1ZP5 A;  1BQO A;  2V4B A;  3HYG A;  1HFC A;  3LIR A;  1QIC A;  1O0Q A;  4PKU A;  3DPF A;  1CQR A;  1QIB A;  1G4K A;  3I7I A;  2DW1 A;  1YOU A;  2X3B A;  1Q3A A;  2DDF A;  1XUR A;  5I4O A;  1KUH A;  1AYK A;  456C A;  4HX3 A;  5B5P A;  3LJT A;  1JAQ A;  1GO8 P;  1C8T A;  3I7G A;  2TCL A;  4XM7 A;  2YIG A;  3G5C A;  1BZS A;  3LIL A;  3TS4 A;  1CGF A;  1I76 A;  3LIK A;  1CIZ A;  1IAG A;  1EB6 A;  1CK7 A;  3G42 A;  4GR3 A;  1Y0V A;  3KEJ A;  3TVC A;  1UMS A;  3N2U A;  1ZS0 A;  2ERQ A;  4QKZ A;  2O36 A;  1GO7 P;  2WO9 A;  1BQQ M;  1OM6 A;  1PWP A;  1O0T A;  2OXU A;  2DW2 A;  2POJ A;  3F1A A;  5CZM A;  3HBU P;  2OY4 A;  1JAP A;  3KEC A;  3L0V A;  5D1U A;  1XFW A;  2AYK A;  3DWB A;  3F16 A;  1BIW A;  4H76 A;  4G0D A;  1AST A;  1KUG A;  5BOT A;  3EDH A;  3EWJ A;  3KRY A;  1UTT A;  1QJI A;  2KRJ A;  1BKC I;  1WNI A;  3ELM A;  1ROS A;  1UMT A;  1D5J A;  3HY9 A;  3U1R A;  1XFX A;  2L0R A;  2PJT A;  4FU4 A;  4L19 A;  4A3W A;  3KEK A;  1C3I A;  4H3X A;  1CAQ A;  4WF6 A;  1OM7 A;  3EHX A;  1MNC A;  1GE5 A;  2DDY A;  4AXQ A;  2DW0 A;  3CKI A;  1ND1 A;  3F19 A;  4H2E A;  3B2Z A;  4WZV A;  5I3M A;  5I12 A;  4FXY P;  3UVC A;  4AIG A;  1ZTQ A;  4CTH A;  1JIZ A;  3K7L A;  3HDB A;  4PKT A;  1S4B P;  3N2V A;  2OW0 A;  1GKD A;  4WK7 A;  4XM6 A;  3KHI A;  1D8F A;  1L6J A;  1UTZ A;  5JMY A;  3OHO A;  1K7G A;  5BPA A;  1OM8 A;  3LQB A;  4I35 A; 
#chains in the Genus database with same CATH topology
 1JKY A;  3SHI A;  1D7X A;  1XUD A;  2I47 A;  2RJQ A;  1OMJ A;  4AYK A;  3DL1 A;  4G9L A;  3DNG A;  4GR0 A;  1JH1 A;  4JP4 A;  5L7F A;  2JIH A;  4JIJ A;  4L6T A;  1XAX A;  1PWU A;  3DSL A;  2WOA A;  2SRT A;  3LGP A;  2OXZ A;  2XS4 A;  1G05 A;  1SU3 A;  4H30 A;  1B8Y A;  3LJZ A;  1J7N A;  4GUY A;  5LAB A;  4IJO A;  2OI0 A;  2Y6C A;  2OXW A;  1UEA A;  1YP1 A;  1HFS A;  4FVL A;  1RM8 A;  1IAC A;  3ZUK A;  4XBH A;  1PWQ A;  3K7N A;  4R3V A;  1XFY A;  1K7I A;  3DTE A;  2D1N A;  3P1V A;  1GE6 A;  3BA0 A;  2O3E A;  4GQL A;  1EUB A;  1K7Q A;  3LKA A;  1JAN A;  5I2Z A;  4IN9 A;  1HV5 A;  2YB9 A;  3LK8 A;  1OZ9 A;  1G9K A;  1IAE A;  3E8R A;  1Y8J A;  2MZH A;  4I03 A;  1GE7 A;  1ZVX A;  2Y6D A;  3B92 A;  1BKC A;  3LJG A;  5D7W A;  4DPE A;  3WV1 A;  1R1J A;  5BOY A;  1SMP A;  1USN A;  3Q2G A;  3F17 A;  1AF0 A;  3O64 A;  3MA2 A;  1IAA A;  1MMQ A;  1GXD A;  1XM5 A;  3AIG A;  1JK3 A;  3O2X A;  2OW2 A;  1R1H A;  3EDI A;  3LUN A;  4GWN A;  3DPE A;  1Z3J A;  2N8R A;  2K9C A;  2E3X A;  4EFS A;  1FM1 A;  4WKI A;  3WV3 A;  3EDZ A;  1CXV A;  1QIA A;  1HOV A;  4JPA A;  1HY7 A;  1BSW A;  3DTK A;  2X3A A;  1JAO A;  2WO8 A;  3P24 A;  1KAP P;  4WKE A;  1YCM A;  1MMB A;  3VI1 A;  5B5O A;  5H8X A;  2MZE A;  2W0D A;  4PKQ A;  3HB2 P;  1CGL A;  3F18 A;  1SAT A;  1YQY A;  1R55 A;  3RTS A;  1BUD A;  1SLM A;  3TSK A;  5D2B A;  4AUO A;  2MZI A;  2ERO A;  2AIG P;  3OHL A;  1XFV A;  3HY7 A;  3KME A;  1BKC E;  1OS9 A;  4GF1 A;  3V96 B;  3KWV C;  1ATL A;  1DMT A;  2RJP A;  4PKR A;  3NX7 A;  2OZR A;  1ZXC A;  2XS3 A;  2W13 A;  3Q2H A;  3AYU A;  830C A;  3L0T A;  1R54 A;  1ZXV A;  3LEA A;  1TVI A;  1SLN A;  4PKS A;  1B3D A;  1H71 P;  2OW9 A;  2JT5 A;  2Z2D A;  1OS2 A;  5I0L A;  5CXA A;  3TT4 A;  1KUK A;  2FV5 A;  1JJ9 A;  4H1Q A;  1EAK A;  2OVX A;  1QJJ A;  5I43 A;  966C A;  1G12 A;  1JIW P;  5L79 A;  3ZXH A;  1XFZ A;  2OVZ A;  4Q1L A;  3VTG A;  2CKI A;  1DTH A;  2JSD A;  4IUW A;  2OW1 A;  1SRP A;  3ZVS A;  1I73 A;  2W15 A;  1I1I P;  1MMP A;  1FBL A;  2J83 A;  1KBC A;  1BUV M;  1PWW A;  4JA1 A;  3DTI A;  1PWV A;  4J4M A;  2D1O A;  2J0T A;  2QPJ A;  2A8H A;  4H49 A;  1BM6 A;  1G49 A;  2OY2 A;  1HTD A;  4DD8 A;  5D1S A;  4ON1 A;  3F15 A;  5D1T A;  4PKW A;  3EHY A;  1IAD A;  4FXQ A;  1MMR A;  2ERP A;  1KUF A;  1AKL A;  1C7K A;  1D8M A;  1A85 A;  4DV8 A;  2FV9 A;  4A7B A;  1CGE A;  4HMA A;  2E2D A;  2MLS A;  4H84 A;  1FLS A;  3HDA P;  4DF9 A;  2HU6 A;  2CLT A;  4PKV A;  4L63 A;  3GBO A;  4XM8 A;  4ZR5 A;  4JQG A;  3B8Z A;  1IAB A;  2W12 A;  3RTT A;  3LQ0 A;  1A86 A;  3LMC A;  3AYK A;  4GWM A;  1GKC A;  1RMZ A;  3KMC A;  2X7M A;  2MLR A;  2JT6 A;  1OO9 A;  2X3C A;  2K2G A;  3LUM A;  4ILW D;  1Y93 A;  4L7A A;  3HBV P;  1QUA A;  5D3C A;  3WV2 A;  4H82 A;  1R1I A;  2USN A;  2JNP A;  3EDG A;  1XFU A;  2W14 A;  3LE9 A;  4XCT A;  4GR8 A;  5CUH A;  1KUI A;  3USN A;  1XUC A;  1ZP5 A;  1BQO A;  2V4B A;  3HYG A;  1HFC A;  3LIR A;  1QIC A;  1O0Q A;  4PKU A;  3DPF A;  1CQR A;  1QIB A;  1G4K A;  3I7I A;  2DW1 A;  1YOU A;  2X3B A;  1Q3A A;  2DDF A;  1XUR A;  5I4O A;  1KUH A;  1AYK A;  456C A;  4HX3 A;  5B5P A;  3LJT A;  1JAQ A;  1GO8 P;  1C8T A;  3I7G A;  2TCL A;  4XM7 A;  2YIG A;  3G5C A;  1BZS A;  3LIL A;  3TS4 A;  1CGF A;  1I76 A;  3LIK A;  1CIZ A;  1IAG A;  1EB6 A;  1CK7 A;  3G42 A;  4GR3 A;  1Y0V A;  3KEJ A;  3TVC A;  1UMS A;  3N2U A;  1ZS0 A;  2ERQ A;  4QKZ A;  2O36 A;  1GO7 P;  2WO9 A;  1BQQ M;  1OM6 A;  1PWP A;  1O0T A;  2OXU A;  2DW2 A;  2POJ A;  3F1A A;  5CZM A;  3HBU P;  2OY4 A;  1JAP A;  3KEC A;  3L0V A;  5D1U A;  1XFW A;  2AYK A;  3DWB A;  3F16 A;  1BIW A;  4H76 A;  4G0D A;  1AST A;  1KUG A;  5BOT A;  3EDH A;  3EWJ A;  3KRY A;  1UTT A;  1QJI A;  2KRJ A;  1BKC I;  1WNI A;  3ELM A;  1ROS A;  1UMT A;  1D5J A;  3HY9 A;  2YUF A;  3U1R A;  1XFX A;  2L0R A;  2PJT A;  4FU4 A;  4L19 A;  4A3W A;  3KEK A;  1C3I A;  4H3X A;  1CAQ A;  4WF6 A;  1OM7 A;  3EHX A;  1MNC A;  1GE5 A;  2DDY A;  4AXQ A;  2DW0 A;  3CKI A;  1ND1 A;  3F19 A;  4H2E A;  3B2Z A;  4WZV A;  5I3M A;  5I12 A;  4FXY P;  3UVC A;  4AIG A;  1ZTQ A;  4CTH A;  1JIZ A;  3K7L A;  3HDB A;  4PKT A;  1S4B P;  3N2V A;  2OW0 A;  1GKD A;  4WK7 A;  4XM6 A;  3KHI A;  1D8F A;  1L6J A;  1UTZ A;  5JMY A;  3OHO A;  1K7G A;  5BPA A;  1OM8 A;  3LQB A;  4I35 A; 
#chains in the Genus database with same CATH homology
 1JKY A;  3SHI A;  1D7X A;  1XUD A;  2I47 A;  2RJQ A;  1OMJ A;  4AYK A;  3DL1 A;  4G9L A;  3DNG A;  4GR0 A;  1JH1 A;  4JP4 A;  5L7F A;  2JIH A;  4JIJ A;  4L6T A;  1PWU A;  3DSL A;  2WOA A;  2SRT A;  3LGP A;  2OXZ A;  2XS4 A;  1G05 A;  1SU3 A;  4H30 A;  1B8Y A;  3LJZ A;  1J7N A;  4GUY A;  5LAB A;  4IJO A;  2OI0 A;  2Y6C A;  2OXW A;  1UEA A;  1YP1 A;  1HFS A;  4FVL A;  1RM8 A;  1IAC A;  3ZUK A;  4XBH A;  1PWQ A;  3K7N A;  4R3V A;  1XFY A;  1K7I A;  3DTE A;  2D1N A;  3P1V A;  1GE6 A;  3BA0 A;  2O3E A;  4GQL A;  1EUB A;  1K7Q A;  3LKA A;  1JAN A;  5I2Z A;  4IN9 A;  1HV5 A;  2YB9 A;  3LK8 A;  1G9K A;  1IAE A;  3E8R A;  1Y8J A;  2MZH A;  4I03 A;  1GE7 A;  1ZVX A;  2Y6D A;  3B92 A;  1BKC A;  3LJG A;  5D7W A;  4DPE A;  3WV1 A;  1R1J A;  5BOY A;  1SMP A;  1USN A;  3Q2G A;  3F17 A;  1AF0 A;  3O64 A;  3MA2 A;  1IAA A;  1MMQ A;  1GXD A;  3AIG A;  1JK3 A;  3O2X A;  2OW2 A;  1R1H A;  3EDI A;  3LUN A;  4GWN A;  3DPE A;  1Z3J A;  2N8R A;  2K9C A;  2E3X A;  4EFS A;  1FM1 A;  4WKI A;  3WV3 A;  3EDZ A;  1CXV A;  1QIA A;  1HOV A;  4JPA A;  1HY7 A;  1BSW A;  3DTK A;  2X3A A;  1JAO A;  2WO8 A;  3P24 A;  1KAP P;  4WKE A;  1YCM A;  1MMB A;  3VI1 A;  5B5O A;  5H8X A;  2MZE A;  2W0D A;  4PKQ A;  3HB2 P;  1CGL A;  3F18 A;  1SAT A;  1YQY A;  1R55 A;  3RTS A;  1BUD A;  1SLM A;  3TSK A;  5D2B A;  4AUO A;  2MZI A;  2ERO A;  2AIG P;  3OHL A;  1XFV A;  3HY7 A;  3KME A;  1BKC E;  1OS9 A;  4GF1 A;  3V96 B;  3KWV C;  1ATL A;  1DMT A;  2RJP A;  4PKR A;  3NX7 A;  2OZR A;  1ZXC A;  2XS3 A;  2W13 A;  3Q2H A;  3AYU A;  830C A;  3L0T A;  1R54 A;  1ZXV A;  3LEA A;  1SLN A;  4PKS A;  1B3D A;  1H71 P;  2OW9 A;  2JT5 A;  2Z2D A;  1OS2 A;  5I0L A;  5CXA A;  3TT4 A;  1KUK A;  2FV5 A;  1JJ9 A;  4H1Q A;  1EAK A;  2OVX A;  1QJJ A;  5I43 A;  966C A;  1G12 A;  1JIW P;  5L79 A;  3ZXH A;  1XFZ A;  2OVZ A;  4Q1L A;  3VTG A;  2CKI A;  1DTH A;  2JSD A;  4IUW A;  2OW1 A;  1SRP A;  3ZVS A;  1I73 A;  2W15 A;  1I1I P;  1MMP A;  1FBL A;  2J83 A;  1KBC A;  1BUV M;  1PWW A;  4JA1 A;  3DTI A;  1PWV A;  4J4M A;  2D1O A;  2J0T A;  2QPJ A;  2A8H A;  4H49 A;  1BM6 A;  1G49 A;  2OY2 A;  1HTD A;  4DD8 A;  5D1S A;  4ON1 A;  3F15 A;  5D1T A;  4PKW A;  3EHY A;  1IAD A;  4FXQ A;  1MMR A;  2ERP A;  1KUF A;  1AKL A;  1C7K A;  1D8M A;  1A85 A;  4DV8 A;  2FV9 A;  4A7B A;  1CGE A;  4HMA A;  2E2D A;  2MLS A;  4H84 A;  1FLS A;  3HDA P;  4DF9 A;  2HU6 A;  2CLT A;  4PKV A;  4L63 A;  3GBO A;  4XM8 A;  4ZR5 A;  4JQG A;  3B8Z A;  1IAB A;  2W12 A;  3RTT A;  3LQ0 A;  1A86 A;  3LMC A;  3AYK A;  4GWM A;  1GKC A;  1RMZ A;  3KMC A;  2X7M A;  2MLR A;  2JT6 A;  1OO9 A;  2X3C A;  2K2G A;  3LUM A;  4ILW D;  1Y93 A;  4L7A A;  3HBV P;  1QUA A;  5D3C A;  3WV2 A;  4H82 A;  1R1I A;  2USN A;  2JNP A;  3EDG A;  1XFU A;  2W14 A;  3LE9 A;  4XCT A;  4GR8 A;  5CUH A;  1KUI A;  3USN A;  1XUC A;  1ZP5 A;  1BQO A;  2V4B A;  3HYG A;  1HFC A;  3LIR A;  1QIC A;  1O0Q A;  4PKU A;  3DPF A;  1CQR A;  1QIB A;  1G4K A;  3I7I A;  2DW1 A;  1YOU A;  2X3B A;  1Q3A A;  2DDF A;  1XUR A;  5I4O A;  1KUH A;  1AYK A;  456C A;  4HX3 A;  5B5P A;  3LJT A;  1JAQ A;  1GO8 P;  1C8T A;  3I7G A;  2TCL A;  4XM7 A;  2YIG A;  3G5C A;  1BZS A;  3LIL A;  3TS4 A;  1CGF A;  1I76 A;  3LIK A;  1CIZ A;  1IAG A;  1EB6 A;  1CK7 A;  3G42 A;  4GR3 A;  1Y0V A;  3KEJ A;  3TVC A;  1UMS A;  3N2U A;  1ZS0 A;  2ERQ A;  4QKZ A;  2O36 A;  1GO7 P;  2WO9 A;  1BQQ M;  1OM6 A;  1PWP A;  1O0T A;  2OXU A;  2DW2 A;  2POJ A;  3F1A A;  5CZM A;  3HBU P;  2OY4 A;  1JAP A;  3KEC A;  3L0V A;  5D1U A;  1XFW A;  2AYK A;  3DWB A;  3F16 A;  1BIW A;  4H76 A;  4G0D A;  1AST A;  1KUG A;  5BOT A;  3EDH A;  3EWJ A;  3KRY A;  1UTT A;  1QJI A;  2KRJ A;  1BKC I;  1WNI A;  3ELM A;  1ROS A;  1UMT A;  1D5J A;  3HY9 A;  2YUF A;  3U1R A;  1XFX A;  2L0R A;  2PJT A;  4FU4 A;  4L19 A;  4A3W A;  3KEK A;  1C3I A;  4H3X A;  1CAQ A;  4WF6 A;  1OM7 A;  3EHX A;  1MNC A;  1GE5 A;  2DDY A;  4AXQ A;  2DW0 A;  3CKI A;  1ND1 A;  3F19 A;  4H2E A;  3B2Z A;  4WZV A;  5I3M A;  5I12 A;  4FXY P;  3UVC A;  4AIG A;  1ZTQ A;  4CTH A;  1JIZ A;  3K7L A;  3HDB A;  4PKT A;  1S4B P;  3N2V A;  2OW0 A;  1GKD A;  4WK7 A;  4XM6 A;  3KHI A;  1D8F A;  1L6J A;  1UTZ A;  5JMY A;  3OHO A;  1K7G A;  5BPA A;  1OM8 A;  3LQB A;  4I35 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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