1R2AA

The molecular basis for protein kinase a anchoring revealed by solution nmr
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
46
structure length
46
Chain Sequence
HMGHIQIPPGLTELLQGYTVEVLRQQPPDLVDFAVEYFTRLREARR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords PROTEIN (CAMP-DEPENDENT PROTEIN KINASE TYPE II REGULATORY SU
publication title The molecular basis for protein kinase A anchoring revealed by solution NMR.
pubmed doi rcsb
source organism Mus musculus
total genus 12
structure length 46
sequence length 46
chains with identical sequence B
ec nomenclature ec 2.7.1.37: Transferred entry: 2.7.11.1, 2.7.11.8, 2.7.11.9, 2.7.11.10, 2.7.11.11,
pdb deposition date 1998-12-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02197 RIIa Regulatory subunit of type II PKA R-subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.890.10 Mainly Alpha Up-down Bundle cAMP-dependent Protein Kinase, Chain A cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain 1r2aA00
1R2AA 4RIQA 2DRNA 2KYGA 5HVZA 2EZWA 3IM3A 2H9RA 3IM4A 4RTAA 4F9KA 2IZYA 1L6EA 4RT4A 3G36A 4ZP3A
chains in the Genus database with same CATH superfamily
4RIQA 3QFYA 3QDEA 2I15A 2CB9A 2CQTA 3IM3A 3S4BA 2H9RA 1L6EA 2KNGA 3ACTA 2DRNA 3S4DA 3IM4A 4RTAA 3RSYA 2CBGA 4F9KA 2CQSA 3PMIA 3S4CA 3UFEA 3QFZA 2K9QA 2OUTA 3S4AA 2KYGA 3QG0A 5HVZA 2EZWA 2IZYA 1R2AA 3RRSA 3GWHA 3ACSA 2RQYA 4RT4A 3AFJA 3G36A 4ZP3A
chains in the Genus database with same CATH topology
1R2AA 4RIQA 2DRNA 2KYGA 5HVZA 2EZWA 3IM3A 2H9RA 3IM4A 4RTAA 4F9KA 2IZYA 1L6EA 4RT4A 3G36A 4ZP3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1R2A A;  4RIQ A;  2DRN A;  2KYG A;  5HVZ A;  2EZW A;  3IM3 A;  2H9R A;  3IM4 A;  4RTA A;  4F9K A;  2IZY A;  1L6E A;  4RT4 A;  3G36 A;  4ZP3 A; 
#chains in the Genus database with same CATH topology
 4RIQ A;  3QFY A;  3QDE A;  2I15 A;  2CB9 A;  2CQT A;  3IM3 A;  3S4B A;  2H9R A;  1L6E A;  2KNG A;  3ACT A;  2DRN A;  3S4D A;  3IM4 A;  4RTA A;  3RSY A;  2CBG A;  4F9K A;  2CQS A;  3PMI A;  3S4C A;  3UFE A;  3QFZ A;  2K9Q A;  2OUT A;  3S4A A;  2KYG A;  3QG0 A;  5HVZ A;  2EZW A;  2IZY A;  1R2A A;  3RRS A;  3GWH A;  3ACS A;  2RQY A;  4RT4 A;  3AFJ A;  3G36 A;  4ZP3 A; 
#chains in the Genus database with same CATH homology
 1R2A A;  4RIQ A;  2DRN A;  2KYG A;  5HVZ A;  2EZW A;  3IM3 A;  2H9R A;  3IM4 A;  4RTA A;  4F9K A;  2IZY A;  1L6E A;  4RT4 A;  3G36 A;  4ZP3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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