1R3FA

Crystal structure of trna pseudouridine synthase trub and its rna complex: rna-protein recognition through a combination of rigid docking and induced fit
Total Genus 79
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
79
sequence length
307
structure length
278
Chain Sequence
GRDINGVLLLDKPQGMSSNDALQKVKRIYNANRAGHTGALDPLATGMLPICLGEATKFSQYLLDSDKRYRVIARLGQRTDTSDADGQIVEERPVTFSAEQLAAALDTFRGDIEQIPITVYELLFIRHEGNELELEIHCSKGTYIRTIIDDLGEKLGCGAHVIYLRRLAVSKYPVERMVTLEHLRELVEQAEQQDIPAAELLDPLLMPMDSPASDYPVVNLPLTSSVYFKNGNPVRTSGAPLEGLVRVTEGENGKFIGMGEIDDEGRVAPRRLVVEYPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of tRNA Pseudouridine Synthase TruB and Its RNA Complex: RNA Recognition Through a Combination of Rigid Docking and Induced Fit
pubmed doi rcsb
molecule keywords tRNA pseudouridine synthase B
molecule tags Lyase
source organism Escherichia coli
total genus 79
structure length 278
sequence length 307
ec nomenclature ec 5.4.99.25: tRNA pseudouridine(55) synthase.
pdb deposition date 2003-10-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01509 TruB_N TruB family pseudouridylate synthase (N terminal domain)
A PF09157 TruB-C_2 Pseudouridine synthase II TruB, C-terminal
A PF16198 TruB_C_2 tRNA pseudouridylate synthase B C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.130.10 Mainly Beta Roll Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 PUA domain 1r3fA02
3.30.2350.10 Alpha Beta 2-Layer Sandwich Pseudouridine synthase Pseudouridine synthase 1r3fA01
1R3FA 3HAXA 3LWQA 4LABA 1WXXA 2APOA 2HVYA 2CX1A 1PRZA 3U28A 3MQKA 4Q1TA 1IQ8A 3UAIA 3D79A 1KSLA 2AS0A 2CWWA 3LWOA 3LDFA 2AB4A 3LWRA 4DMGA 1V9FA 1IT7A 2I82A 1SGVA 1ZE1A 1K8WA 3HJWA 1SQWA 1QYUA 2ISTA 2J5VA 3VSEA 1Q7HA 1KSVA 1KSKA 3LWVA 1ZL3A 1XPIA 1ZE2A 2CX0A 2AUSA 1V9KA 3DH3A 4LGTA 1WXWA 2B78A 1J2BA 2EY4A 1IT8A 1ZS7A 3C0KA 3HJYA 2P38A 1T5YA 2RFKA 2J5TA 1R3EA 3LWPA 2Q07A
chains in the Genus database with same CATH superfamily
2FRXA 3U28A 1S04A 1IQ8A 3D79A 2AS0A 2CWWA 2KKUA 4DMGA 1IT7A 1SGVA 1KSVA 1XPIA 2E5OA 3M4XA 2DP9A 1IT8A 1SI7A 1ZBOA 2RFKA 3M6WA 3HAXA 2HVYA 3M6XA 2CX1A 4Q1TA 1KSLA 1TE7A 1XNEA 3LWOA 1V9FA 1SZWA 3LWVA 1QYUA 2J5VA 2ISTA 1Q7HA 2AUSA 3DH3A 4CI3B 3LJCA 1Z2ZA 3C0KA 3LDFA 1KSKA 1R3FA 1UOYA 3LWQA 1PRZA 3MQKA 3M6VA 3UAIA 1WK2A 2AB4A 4TZ4C 2Z0TA 1SQWA 4CI2B 1ZE2A 2CX0A 4LGTA 1WXWA 2EY4A 4CI1B 1ZS7A 3HJYA 2J5TA 3LWPA 2Q07A 1SB7A 2ANEA 1WXXA 2APOA 3M6UA 3M65A 3LWRA 2I82A 1ZE1A 3IUWA 1K8WA 3VSEA 1ZL3A 1V9KA 3ZV0C 2B78A 1J2BA 2P38A 1T5YA 3HJWA 1R3EA 4LABA
chains in the Genus database with same CATH topology
1R3FA 1SB7A 3HAXA 3LWQA 4LABA 1WXXA 2APOA 2HVYA 2CX1A 1PRZA 3U28A 3MQKA 4Q1TA 1IQ8A 3UAIA 3D79A 1KSLA 2AS0A 2CWWA 3LWOA 3LDFA 2AB4A 3LWRA 4DMGA 1V9FA 1IT7A 2I82A 1SGVA 1SZWA 1ZE1A 1K8WA 3HJWA 1SQWA 1QYUA 2ISTA 2J5VA 3VSEA 1Q7HA 1KSVA 1KSKA 3LWVA 1ZL3A 1XPIA 1ZE2A 2CX0A 2AUSA 1V9KA 3DH3A 4LGTA 1WXWA 2B78A 1J2BA 2EY4A 1IT8A 1SI7A 1Z2ZA 1ZS7A 3C0KA 3HJYA 2P38A 1T5YA 2RFKA 2J5TA 1R3EA 3LWPA 2Q07A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1R3F A;  3HAX A;  3LWQ A;  4LAB A;  1WXX A;  2APO A;  2HVY A;  2CX1 A;  1PRZ A;  3U28 A;  3MQK A;  4Q1T A;  1IQ8 A;  3UAI A;  3D79 A;  1KSL A;  2AS0 A;  2CWW A;  3LWO A;  3LDF A;  2AB4 A;  3LWR A;  4DMG A;  1V9F A;  1IT7 A;  2I82 A;  1SGV A;  1ZE1 A;  1K8W A;  3HJW A;  1SQW A;  1QYU A;  2IST A;  2J5V A;  3VSE A;  1Q7H A;  1KSV A;  1KSK A;  3LWV A;  1ZL3 A;  1XPI A;  1ZE2 A;  2CX0 A;  2AUS A;  1V9K A;  3DH3 A;  4LGT A;  1WXW A;  2B78 A;  1J2B A;  2EY4 A;  1IT8 A;  1ZS7 A;  3C0K A;  3HJY A;  2P38 A;  1T5Y A;  2RFK A;  2J5T A;  1R3E A;  3LWP A;  2Q07 A; 
#chains in the Genus database with same CATH topology
 2FRX A;  3U28 A;  1S04 A;  1IQ8 A;  3D79 A;  2AS0 A;  2CWW A;  2KKU A;  4DMG A;  1IT7 A;  1SGV A;  1KSV A;  1XPI A;  2E5O A;  3M4X A;  2DP9 A;  1IT8 A;  1SI7 A;  1ZBO A;  2RFK A;  3M6W A;  3HAX A;  2HVY A;  3M6X A;  2CX1 A;  4Q1T A;  1KSL A;  1TE7 A;  1XNE A;  3LWO A;  1V9F A;  1SZW A;  3LWV A;  1QYU A;  2J5V A;  2IST A;  1Q7H A;  2AUS A;  3DH3 A;  4CI3 B;  3LJC A;  1Z2Z A;  3C0K A;  3LDF A;  1KSK A;  1R3F A;  1UOY A;  3LWQ A;  1PRZ A;  3MQK A;  3M6V A;  3UAI A;  1WK2 A;  2AB4 A;  4TZ4 C;  2Z0T A;  1SQW A;  4CI2 B;  1ZE2 A;  2CX0 A;  4LGT A;  1WXW A;  2EY4 A;  4CI1 B;  1ZS7 A;  3HJY A;  2J5T A;  3LWP A;  2Q07 A;  1SB7 A;  2ANE A;  1WXX A;  2APO A;  3M6U A;  3M65 A;  3LWR A;  2I82 A;  1ZE1 A;  3IUW A;  1K8W A;  3VSE A;  1ZL3 A;  1V9K A;  3ZV0 C;  2B78 A;  1J2B A;  2P38 A;  1T5Y A;  3HJW A;  1R3E A;  4LAB A; 
#chains in the Genus database with same CATH homology
 1R3F A;  1SB7 A;  3HAX A;  3LWQ A;  4LAB A;  1WXX A;  2APO A;  2HVY A;  2CX1 A;  1PRZ A;  3U28 A;  3MQK A;  4Q1T A;  1IQ8 A;  3UAI A;  3D79 A;  1KSL A;  2AS0 A;  2CWW A;  3LWO A;  3LDF A;  2AB4 A;  3LWR A;  4DMG A;  1V9F A;  1IT7 A;  2I82 A;  1SGV A;  1SZW A;  1ZE1 A;  1K8W A;  3HJW A;  1SQW A;  1QYU A;  2IST A;  2J5V A;  3VSE A;  1Q7H A;  1KSV A;  1KSK A;  3LWV A;  1ZL3 A;  1XPI A;  1ZE2 A;  2CX0 A;  2AUS A;  1V9K A;  3DH3 A;  4LGT A;  1WXW A;  2B78 A;  1J2B A;  2EY4 A;  1IT8 A;  1SI7 A;  1Z2Z A;  1ZS7 A;  3C0K A;  3HJY A;  2P38 A;  1T5Y A;  2RFK A;  2J5T A;  1R3E A;  3LWP A;  2Q07 A; 
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similar chains in the pdb database (?% sequence similarity)

 
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